GREMLIN Database
FLGI - Flagellar P-ring protein
UniProt: P0A6S3 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG20265
Length: 365 (356)
Sequences: 1254 (763)
Seq/√Len: 40.5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
82_K114_K5.3141.00
89_V124_T5.0221.00
26_T200_I3.8851.00
33_Q92_S3.6341.00
294_D298_G3.3581.00
99_Q174_E3.3151.00
203_T242_M3.2401.00
275_V282_V3.0511.00
290_V305_T3.0081.00
150_A286_R2.9651.00
27_S190_N2.9251.00
51_Q80_Q2.8111.00
208_R235_F2.7441.00
286_R308_T2.7301.00
223_V239_I2.7241.00
273_C352_M2.6981.00
22_I200_I2.6781.00
23_R193_D2.6241.00
253_V358_L2.6021.00
319_L335_L2.5921.00
289_N305_T2.5681.00
200_I221_I2.5431.00
189_L197_A2.4861.00
22_I239_I2.3901.00
83_N109_S2.2811.00
292_Q302_T2.2231.00
207_V238_D2.2201.00
151_G286_R2.2161.00
288_A307_Q2.2010.99
332_V349_L2.1790.99
195_S199_Q2.1620.99
271_D359_R2.1600.99
199_Q246_V2.1480.99
31_V194_F2.1420.99
51_Q112_N2.1410.99
291_S305_T2.1380.99
23_R240_Q2.1120.99
155_V312_L2.0600.99
105_V137_A2.0570.99
314_Q343_M2.0170.99
276_A319_L2.0090.99
217_D220_T1.9860.99
151_G308_T1.9810.99
98_R217_D1.9800.99
294_D297_F1.9710.99
157_V314_Q1.9550.99
28_V187_L1.9280.99
192_E219_R1.9030.99
19_A243_Q1.9000.98
141_I163_G1.8840.98
129_V136_L1.8820.98
292_Q300_G1.8810.98
93_L171_I1.8480.98
26_T187_L1.8210.98
329_N333_R1.8150.98
21_R193_D1.7980.98
51_Q54_Q1.7860.98
56_P112_N1.7470.97
92_S102_T1.7410.97
46_D160_L1.7310.97
21_R24_D1.7030.97
32_R172_E1.6900.97
205_N213_A1.6810.97
23_R248_P1.6750.97
319_L331_V1.6460.96
291_S303_V1.6430.96
62_L69_L1.6430.96
25_L200_I1.6390.96
291_S302_T1.6310.96
225_V232_Q1.6300.96
146_A312_L1.6250.96
289_N307_Q1.6110.96
80_Q112_N1.6050.96
21_R251_A1.6040.96
270_L331_V1.6020.96
41_L84_V1.5980.96
153_S308_T1.5830.95
20_E359_R1.5770.95
28_V236_L1.5690.95
98_R220_T1.5510.95
270_L357_C1.5430.95
253_V362_L1.5330.94
135_A169_A1.5330.94
200_I244_V1.5230.94
25_L246_V1.5150.94
320_Q338_L1.5100.94
37_I122_L1.5050.94
55_T81_L1.4960.94
252_K363_E1.4870.93
288_A306_P1.4680.93
90_T120_T1.4620.93
23_R251_A1.4560.93
226_P235_F1.4460.92
54_Q81_L1.4330.92
197_A201_A1.4120.91
186_N220_T1.4050.91
26_T240_Q1.3930.91
293_P302_T1.3900.91
127_K132_Q1.3780.90
215_A233_V1.3680.90
256_N259_T1.3390.89
147_G343_M1.3340.89
257_S346_M1.3300.89
51_Q82_K1.3210.88
93_L175_L1.3130.88
216_L222_Q1.3100.88
207_V242_M1.3080.88
328_L345_L1.3070.88
54_Q112_N1.3050.88
144_G347_S1.2990.88
282_V331_V1.2940.87
195_S240_Q1.2880.87
141_I313_R1.2880.87
184_T222_Q1.2860.87
254_V363_E1.2800.87
208_R239_I1.2740.87
179_F236_L1.2740.87
201_A215_A1.2730.87
286_R306_P1.2660.86
51_Q56_P1.2650.86
115_S143_V1.2260.84
298_G302_T1.2240.84
54_Q80_Q1.2120.84
255_I346_M1.1930.83
257_S343_M1.1900.83
195_S241_N1.1830.82
39_Y86_A1.1710.82
149_S310_I1.1620.81
290_V293_P1.1590.81
171_I175_L1.1590.81
198_Q202_D1.1590.81
123_M331_V1.1560.81
288_A305_T1.1550.81
88_M122_L1.1520.80
22_I26_T1.1510.80
193_D240_Q1.1390.80
156_Q160_L1.1390.80
201_A221_I1.1340.79
142_L364_I1.1270.79
107_V141_I1.1230.79
150_A308_T1.1190.78
303_V307_Q1.1140.78
159_Q286_R1.0910.77
81_L112_N1.0910.77
11_L19_A1.0860.76
156_Q284_V1.0800.76
46_D161_N1.0770.76
130_D134_Y1.0760.76
293_P300_G1.0640.75
197_A221_I1.0570.74
35_S170_V1.0550.74
300_G339_G1.0470.74
290_V303_V1.0430.73
164_R350_Q1.0430.73
16_A19_A1.0400.73
57_F81_L1.0390.73
22_I201_A1.0270.72
33_Q102_T1.0260.72
61_T65_M1.0230.72
159_Q162_G1.0170.71
117_R143_V1.0060.71
35_S136_L1.0060.71
322_V338_L1.0050.71
235_F239_I1.0000.70
23_R196_M1.0000.70
291_S300_G0.9980.70
320_Q335_L0.9960.70
31_V96_F0.9940.70
106_V162_G0.9900.69
69_L335_L0.9900.69
152_G341_T0.9890.69
250_D361_K0.9880.69
104_D193_D0.9850.69
304_V307_Q0.9820.69
39_Y61_T0.9730.68
61_T86_A0.9670.68
214_T222_Q0.9580.67
12_L19_A0.9580.67
195_S237_A0.9570.67
290_V302_T0.9570.67
97_G171_I0.9530.66
50_D125_P0.9510.66
15_T18_Q0.9470.66
122_L133_V0.9390.65
21_R248_P0.9370.65
281_S364_I0.9350.65
98_R174_E0.9340.65
21_R240_Q0.9320.65
25_L244_V0.9320.65
336_N342_P0.9310.65
272_S352_M0.9280.64
285_N311_D0.9280.64
61_T66_L0.9180.63
13_V18_Q0.9160.63
54_Q256_N0.9150.63
66_L86_A0.9150.63
204_I242_M0.9140.63
202_D206_R0.9140.63
231_S234_R0.9110.63
270_L352_M0.9110.63
259_T277_Q0.9090.63
127_K241_N0.9020.62
88_M124_T0.9010.62
123_M136_L0.8920.61
103_I171_I0.8910.61
354_S363_E0.8870.61
91_A103_I0.8860.61
188_Q219_R0.8860.61
41_L284_V0.8800.60
201_A230_S0.8780.60
290_V304_V0.8760.60
149_S154_S0.8660.59
128_G132_Q0.8570.58
37_I71_I0.8560.58
12_L15_T0.8530.58
197_A233_V0.8520.58
142_L257_S0.8510.58
96_F199_Q0.8490.57
130_D173_R0.8460.57
67_S273_C0.8400.57
277_Q347_S0.8400.57
215_A340_A0.8380.56
129_V199_Q0.8340.56
291_S298_G0.8320.56
8_L204_I0.8270.55
148_A155_V0.8260.55
188_Q220_T0.8250.55
21_R217_D0.8220.55
225_V229_N0.8220.55
117_R257_S0.8220.55
322_V335_L0.8190.55
339_G342_P0.8160.54
98_R219_R0.8150.54
192_E197_A0.8150.54
212_S235_F0.8120.54
193_D251_A0.8110.54
215_A226_P0.8090.54
113_A185_L0.8070.54
93_L162_G0.7990.53
10_L17_A0.7960.53
330_N333_R0.7870.52
157_V257_S0.7850.52
179_F194_F0.7830.51
285_N289_N0.7820.51
148_A310_I0.7820.51
79_M363_E0.7780.51
39_Y58_T0.7780.51
264_M282_V0.7750.51
319_L322_V0.7710.50
61_T109_S0.7690.50
105_V214_T0.7690.50
66_L71_I0.7680.50
144_G259_T0.7670.50
112_N161_N0.7650.50
222_Q252_K0.7640.50
159_Q277_Q0.7630.50
65_M342_P0.7620.49
50_D360_A0.7600.49
58_T109_S0.7580.49
361_K364_I0.7570.49
136_L170_V0.7560.49
192_E265_N0.7550.49
69_L277_Q0.7540.49
196_M248_P0.7530.49
99_Q171_I0.7530.49
215_A236_L0.7530.49
89_V105_V0.7530.49
144_G344_D0.7530.49
68_Q101_Q0.7520.49
67_S262_V0.7510.48
56_P81_L0.7500.48
196_M246_V0.7470.48
183_N224_R0.7450.48
163_G262_V0.7450.48
199_Q248_P0.7440.48
51_Q161_N0.7390.47
237_A241_N0.7370.47
208_R238_D0.7350.47
196_M357_C0.7330.47
28_V60_Q0.7320.47
288_A304_V0.7270.46
328_L336_N0.7260.46
92_S170_V0.7260.46
35_S92_S0.7250.46
185_L220_T0.7240.46
261_S265_N0.7230.46
58_T84_V0.7220.46
29_Q186_N0.7200.46
69_L354_S0.7190.45
50_D112_N0.7180.45
89_V102_T0.7160.45
221_I244_V0.7140.45
144_G329_N0.7140.45
74_P78_N0.7130.45
290_V300_G0.7080.44
22_I212_S0.7070.44
331_V335_L0.7070.44
43_V187_L0.7060.44
202_D234_R0.7050.44
327_S331_V0.7020.44
46_D125_P0.7010.44
58_T86_A0.7010.44
64_N72_T0.7000.44
59_T62_L0.6990.44
326_A330_N0.6990.44
201_A251_A0.6990.44
9_I12_L0.6960.43
274_A336_N0.6960.43
34_N172_E0.6930.43
57_F73_V0.6920.43
120_T362_L0.6910.43
347_S350_Q0.6890.43
224_R239_I0.6860.42
202_D311_D0.6860.42
29_Q262_V0.6850.42
52_T80_Q0.6850.42
232_Q256_N0.6830.42
50_D64_N0.6820.42
272_S324_S0.6820.42
199_Q240_Q0.6810.42
270_L273_C0.6810.42
233_V270_L0.6810.42
25_L307_Q0.6800.42
66_L285_N0.6790.42
120_T132_Q0.6770.42
108_S185_L0.6740.41
63_N75_T0.6720.41
186_N222_Q0.6710.41
33_Q170_V0.6700.41
136_L281_S0.6690.41
264_M327_S0.6680.41
223_V347_S0.6670.41
79_M88_M0.6650.41
8_L254_V0.6650.41
287_Q309_Q0.6640.41
6_S113_A0.6640.41
77_T154_S0.6630.40
56_P158_N0.6620.40
165_I263_V0.6620.40
26_T109_S0.6610.40
190_N361_K0.6610.40
12_L17_A0.6600.40
179_F218_A0.6600.40
192_E218_A0.6600.40
265_N306_P0.6600.40
321_S326_A0.6590.40
54_Q59_T0.6580.40
8_L12_L0.6570.40
135_A189_L0.6570.40
152_G286_R0.6560.40
9_I13_V0.6550.40
107_V355_A0.6540.40
219_R261_S0.6540.40
185_L239_I0.6540.40
186_N275_V0.6540.40
279_N315_S0.6530.40
215_A232_Q0.6520.39
43_V109_S0.6500.39
60_Q235_F0.6490.39
94_P103_I0.6490.39
81_L84_V0.6490.39
177_S256_N0.6450.39
226_P277_Q0.6450.39
263_V297_F0.6440.39
74_P282_V0.6430.39
156_Q159_Q0.6430.39
298_G351_S0.6430.39
71_I340_A0.6420.39
330_N343_M0.6390.38
156_Q281_S0.6370.38
353_Q360_A0.6360.38
102_T170_V0.6360.38
294_D323_R0.6350.38
208_R212_S0.6340.38
234_R237_A0.6340.38
14_T17_A0.6330.38
39_Y57_F0.6320.38
41_L57_F0.6320.38
14_T18_Q0.6290.37
185_L236_L0.6280.37
109_S236_L0.6260.37
298_G308_T0.6260.37
252_K315_S0.6260.37
33_Q296_P0.6240.37
57_F86_A0.6220.37
62_L78_N0.6220.37
55_T80_Q0.6220.37
209_G223_V0.6210.37
69_L243_Q0.6200.37
275_V315_S0.6180.36
287_Q307_Q0.6140.36
152_G306_P0.6130.36
270_L285_N0.6110.36
48_T225_V0.6110.36
264_M276_A0.6100.36
55_T59_T0.6100.36
48_T141_I0.6090.36
103_I316_G0.6090.36
226_P233_V0.6060.35
57_F71_I0.6060.35
214_T227_S0.6050.35
146_A308_T0.6050.35
340_A345_L0.6040.35
43_V122_L0.6030.35
51_Q114_K0.6020.35
109_S112_N0.6010.35
8_L16_A0.6000.35
346_M359_R0.6000.35
39_Y66_L0.6000.35
208_R231_S0.5980.35
18_Q245_N0.5980.35
128_G134_Y0.5980.35
294_D299_G0.5970.35
258_R351_S0.5960.35
149_S153_S0.5950.35
10_L214_T0.5940.34
232_Q244_V0.5940.34
122_L194_F0.5920.34
105_V113_A0.5900.34
246_V359_R0.5900.34
62_L322_V0.5890.34
203_T206_R0.5840.34
28_V185_L0.5820.33
107_V285_N0.5820.33
51_Q64_N0.5820.33
13_V17_A0.5810.33
187_L200_I0.5780.33
232_Q257_S0.5750.33
127_K133_V0.5740.33
84_V284_V0.5740.33
72_T81_L0.5740.33
131_S332_V0.5730.33
95_P316_G0.5730.33
120_T162_G0.5710.33
180_G262_V0.5710.33
35_S350_Q0.5700.32
153_S286_R0.5690.32
282_V347_S0.5690.32
195_S322_V0.5680.32
28_V179_F0.5680.32
136_L262_V0.5670.32
7_A16_A0.5670.32
96_F217_D0.5660.32
20_E362_L0.5660.32
130_D217_D0.5660.32
23_R195_S0.5650.32
64_N74_P0.5650.32
352_M357_C0.5640.32
145_G258_R0.5630.32
255_I362_L0.5620.32
92_S361_K0.5600.32
88_M329_N0.5600.32
330_N361_K0.5590.32
31_V39_Y0.5570.31
182_G256_N0.5570.31
282_V307_Q0.5550.31
277_Q345_L0.5540.31
201_A218_A0.5540.31
297_F308_T0.5520.31
265_N327_S0.5520.31
8_L227_S0.5510.31
41_L129_V0.5510.31
284_V310_I0.5510.31
288_A310_I0.5510.31
8_L11_L0.5500.31
293_P304_V0.5490.31
22_I242_M0.5490.31
262_V265_N0.5480.31
273_C284_V0.5480.31
309_Q312_L0.5460.31
275_V354_S0.5460.31
51_Q81_L0.5450.31
117_R343_M0.5450.31
114_K154_S0.5430.30
93_L284_V0.5430.30
123_M221_I0.5430.30
74_P77_T0.5420.30
343_M346_M0.5410.30
27_S241_N0.5410.30
318_S326_A0.5400.30
186_N284_V0.5400.30
64_N112_N0.5400.30
200_I242_M0.5390.30
17_A95_P0.5370.30
72_T288_A0.5360.30
242_M250_D0.5350.30
92_S95_P0.5330.30
327_S357_C0.5320.29
225_V228_G0.5320.29
101_Q334_A0.5310.29
37_I200_I0.5310.29
120_T156_Q0.5310.29
101_Q188_Q0.5300.29
10_L14_T0.5290.29
105_V169_A0.5280.29
140_N162_G0.5280.29
275_V340_A0.5260.29
88_M110_M0.5260.29
13_V224_R0.5250.29
261_S363_E0.5240.29
31_V93_L0.5220.29
163_G227_S0.5220.29
6_S10_L0.5210.29
179_F232_Q0.5210.29
317_G324_S0.5200.29
68_Q331_V0.5200.29
353_Q361_K0.5170.28
255_I325_S0.5170.28
144_G255_I0.5160.28
319_L342_P0.5160.28
25_L61_T0.5160.28
262_V269_T0.5150.28
123_M130_D0.5150.28
28_V91_A0.5150.28
220_T231_S0.5150.28
41_L65_M0.5150.28
328_L332_V0.5140.28
146_A157_V0.5130.28
109_S258_R0.5130.28
214_T224_R0.5110.28
93_L96_F0.5090.28
127_K352_M0.5090.28
211_G214_T0.5080.28
35_S221_I0.5070.28
340_A362_L0.5070.28
193_D217_D0.5060.28
37_I65_M0.5050.27
238_D276_A0.5040.27
277_Q333_R0.5020.27
296_P322_V0.5020.27
64_N331_V0.5020.27
140_N327_S0.5010.27
193_D241_N0.5010.27
37_I175_L0.5000.27
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4p8nA 1 0.3589 30.5 0.977 Contact Map
3smaA 2 0.1315 24.6 0.978 Contact Map
2kueA 1 0.3507 13.1 0.981 Contact Map
1a62A 1 0.1397 8.7 0.982 Contact Map
1g6uA 3 0.1151 8.5 0.983 Contact Map
2pn6A 5 0.1397 7.6 0.983 Contact Map
4g08A 1 0.3726 7.1 0.983 Contact Map
2kufA 1 0.3397 7.1 0.983 Contact Map
2ma3A 1 0.2274 7 0.983 Contact Map
4un2B 1 0.1123 6.8 0.983 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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