GREMLIN Database
FLGH - Flagellar L-ring protein
UniProt: P0A6S0 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG20264
Length: 232 (216)
Sequences: 1377 (1021)
Seq/√Len: 69.5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
78_L184_V4.6611.00
160_N183_V3.6771.00
154_Q162_H3.4941.00
180_F200_V3.1881.00
95_N133_N2.9821.00
97_S131_T2.8041.00
152_V161_L2.7241.00
163_V200_V2.6721.00
185_N188_T2.6541.00
80_I200_V2.5801.00
78_L150_V2.5301.00
150_V163_V2.4221.00
78_L189_I2.4131.00
80_I163_V2.3811.00
74_I154_Q2.3221.00
95_N137_G2.3071.00
81_V194_T2.2201.00
94_A138_A2.2021.00
99_D131_T2.1991.00
94_A217_Q2.0741.00
101_K131_T2.0291.00
18_S21_G2.0151.00
34_A37_A1.9621.00
190_S194_T1.9621.00
140_A174_G1.9491.00
99_D129_G1.9251.00
146_G197_S1.8941.00
31_V34_A1.8331.00
95_N135_K1.8281.00
98_R223_Q1.8261.00
184_V195_V1.7801.00
156_L162_H1.7731.00
166_E179_R1.7631.00
93_S139_N1.7211.00
35_T38_Q1.7081.00
48_N53_Q1.7011.00
103_N125_E1.6811.00
99_D133_N1.6801.00
34_A38_Q1.6530.99
12_S16_V1.6080.99
84_E197_S1.6030.99
90_K144_F1.5480.99
80_I180_F1.5390.99
32_Q35_T1.5310.99
101_K129_G1.5290.99
212_Y219_M1.5260.99
32_Q36_S1.4950.99
97_S135_K1.4930.99
176_E207_Y1.4800.99
170_A208_V1.4720.99
29_P33_G1.4680.99
86_V176_E1.4490.99
107_D125_E1.4440.99
179_R206_E1.4440.99
90_K174_G1.4000.98
167_K176_E1.3990.98
36_S39_P1.3830.98
79_T149_T1.3790.98
29_P32_Q1.3780.98
83_Q196_P1.3750.98
74_I155_V1.3720.98
82_L146_G1.3480.98
172_N209_G1.3430.98
11_I16_V1.3210.97
218_N224_R1.3180.97
31_V35_T1.3180.97
93_S135_K1.3060.97
173_Q214_N1.2980.97
96_A216_A1.2820.97
31_V36_S1.2770.97
150_V165_G1.2740.97
69_R187_R1.2640.97
147_T198_T1.2620.96
90_K176_E1.2590.96
104_F107_D1.2520.96
162_H183_V1.2510.96
151_T202_D1.2460.96
88_A142_N1.2410.96
11_I15_L1.2380.96
31_V37_A1.2370.96
87_S141_S1.2280.96
64_P67_E1.2200.96
84_E169_I1.2160.96
147_T199_Q1.2020.95
91_S137_G1.1900.95
226_F230_S1.1690.95
35_T39_P1.1640.94
105_G127_S1.1620.94
75_G165_G1.1600.94
219_M227_L1.1430.94
16_V20_T1.1410.94
127_S131_T1.1060.93
173_Q218_N1.1010.93
49_G52_F1.0850.92
94_A134_G1.0840.92
30_L33_G1.0780.92
86_V146_G1.0770.92
134_G211_G1.0730.92
103_N129_G1.0720.92
148_L178_I1.0680.91
93_S137_G1.0650.91
136_G213_I1.0630.91
32_Q38_Q1.0620.91
144_F184_V1.0450.91
168_Q204_R1.0270.90
97_S133_N1.0270.90
91_S139_N1.0270.90
33_G37_A1.0240.90
142_N219_M1.0180.89
81_V147_T1.0130.89
168_Q208_V0.9960.88
146_G176_E0.9890.88
94_A172_N0.9880.88
142_N174_G0.9820.88
89_S141_S0.9810.88
11_I14_L0.9720.87
173_Q217_Q0.9680.87
86_V226_F0.9590.86
15_L19_L0.9400.85
142_N172_N0.9350.85
30_L34_A0.9340.85
102_T126_A0.9300.85
170_A175_T0.9250.84
82_L174_G0.9180.84
66_F183_V0.9150.84
188_T211_G0.9140.84
136_G211_G0.9070.83
142_N176_E0.9050.83
147_T197_S0.8990.83
81_V190_S0.8840.82
95_N139_N0.8830.81
77_T168_Q0.8820.81
113_L180_F0.8800.81
171_I174_G0.8740.81
172_N217_Q0.8670.80
139_N143_T0.8660.80
160_N186_P0.8640.80
140_A176_E0.8640.80
181_S204_R0.8550.79
109_V124_V0.8530.79
72_R225_F0.8510.79
33_G39_P0.8460.79
86_V142_N0.8410.78
142_N166_E0.8400.78
77_T135_K0.8360.78
90_K167_K0.8310.77
196_P199_Q0.8310.77
73_N155_V0.8290.77
51_I151_T0.8290.77
164_V181_S0.8270.77
150_V180_F0.8250.77
140_A185_N0.8250.77
212_Y215_E0.8240.77
88_A152_V0.8210.77
173_Q212_Y0.8200.76
142_N177_F0.8140.76
14_L19_L0.8120.76
101_K127_S0.8080.75
16_V23_A0.8080.75
11_I27_S0.8070.75
84_E146_G0.8030.75
171_I176_E0.8000.75
18_S43_P0.7930.74
12_S18_S0.7900.74
106_F126_A0.7870.73
27_S31_V0.7870.73
146_G174_G0.7800.73
82_L140_A0.7770.72
70_R97_S0.7720.72
154_Q161_L0.7720.72
140_A171_I0.7720.72
165_G207_Y0.7710.72
96_A136_G0.7710.72
219_M223_Q0.7640.71
130_N214_N0.7630.71
84_E167_K0.7630.71
41_P72_R0.7570.71
22_C75_G0.7480.70
70_R230_S0.7480.70
52_F56_Q0.7470.69
140_A207_Y0.7420.69
90_K207_Y0.7410.69
16_V24_W0.7390.69
103_N127_S0.7380.69
165_G203_A0.7370.68
52_F197_S0.7360.68
209_G214_N0.7240.67
10_A16_V0.7220.67
25_I28_T0.7220.67
142_N207_Y0.7180.66
96_A227_L0.7130.66
42_G129_G0.7080.65
126_A132_F0.7030.65
226_F229_L0.7010.65
85_N143_T0.6990.64
104_F128_G0.6970.64
92_S217_Q0.6960.64
15_L18_S0.6940.64
67_E72_R0.6880.63
88_A200_V0.6850.63
72_R186_P0.6820.62
174_G207_Y0.6780.62
13_S17_L0.6760.62
78_L230_S0.6690.61
90_K142_N0.6670.61
94_A199_Q0.6640.60
82_L150_V0.6580.60
138_A217_Q0.6550.59
44_T131_T0.6520.59
35_T164_V0.6510.59
168_Q175_T0.6420.58
142_N167_K0.6420.58
138_A173_Q0.6410.58
49_G167_K0.6410.58
140_A214_N0.6390.57
151_T201_A0.6390.57
50_S53_Q0.6380.57
89_S137_G0.6380.57
205_I232_M0.6350.57
94_A213_I0.6340.57
70_R176_E0.6330.57
229_L232_M0.6320.57
180_F205_I0.6290.56
62_Y93_S0.6270.56
204_R208_V0.6250.56
173_Q220_G0.6220.55
55_A62_Y0.6200.55
171_I217_Q0.6180.55
25_I145_S0.6140.54
50_S56_Q0.6090.54
181_S200_V0.6070.54
65_L144_F0.6030.53
92_S138_A0.6010.53
149_T212_Y0.6000.53
23_A26_P0.6000.53
129_G133_N0.6000.53
90_K138_A0.5990.53
86_V169_I0.5980.53
10_A38_Q0.5920.52
81_V192_S0.5910.52
68_D94_A0.5900.52
211_G220_G0.5890.51
32_Q37_A0.5880.51
124_V226_F0.5880.51
11_I103_N0.5850.51
52_F146_G0.5830.51
171_I227_L0.5820.51
37_A40_V0.5820.51
64_P181_S0.5810.51
52_F122_A0.5810.51
17_L23_A0.5800.50
80_I188_T0.5750.50
33_G36_S0.5750.50
112_Y124_V0.5740.50
81_V191_G0.5740.50
99_D103_N0.5730.50
93_S101_K0.5720.49
56_Q163_V0.5720.49
73_N127_S0.5700.49
46_V135_K0.5700.49
167_K197_S0.5690.49
222_L226_F0.5690.49
83_Q198_T0.5680.49
85_N197_S0.5670.49
89_S139_N0.5660.49
157_V160_N0.5650.49
38_Q162_H0.5630.48
106_F205_I0.5630.48
17_L21_G0.5600.48
88_A155_V0.5580.48
64_P145_S0.5560.47
100_G223_Q0.5550.47
148_L166_E0.5540.47
161_L200_V0.5540.47
100_G104_F0.5530.47
92_S209_G0.5520.47
168_Q195_V0.5520.47
186_P206_E0.5510.47
88_A208_V0.5500.47
142_N146_G0.5500.47
146_G179_R0.5480.47
70_R207_Y0.5480.47
40_V55_A0.5480.47
104_F126_A0.5470.46
64_P70_R0.5470.46
38_Q154_Q0.5460.46
67_E160_N0.5450.46
98_R130_N0.5390.45
54_S152_V0.5390.45
108_T122_A0.5390.45
29_P38_Q0.5390.45
180_F214_N0.5390.45
25_I162_H0.5390.45
107_D122_A0.5370.45
88_A136_G0.5370.45
47_A99_D0.5360.45
15_L54_S0.5360.45
10_A105_G0.5350.45
12_S20_T0.5350.45
11_I116_L0.5330.45
41_P154_Q0.5320.45
68_D71_P0.5290.44
66_F168_Q0.5280.44
100_G128_G0.5260.44
28_T215_E0.5260.44
113_L120_A0.5230.44
154_Q158_N0.5220.43
160_N202_D0.5220.43
146_G220_G0.5190.43
164_V179_R0.5180.43
147_T194_T0.5170.43
112_Y121_R0.5160.43
185_N211_G0.5130.42
90_K177_F0.5130.42
52_F62_Y0.5120.42
90_K178_I0.5120.42
100_G127_S0.5110.42
48_N229_L0.5110.42
166_E177_F0.5110.42
219_M224_R0.5090.42
63_Q67_E0.5070.42
49_G197_S0.5060.42
164_V225_F0.5040.41
11_I20_T0.5000.41
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3zbiC 1 0.1164 79.3 0.938 Contact Map
3bdlA 2 0.3276 26 0.957 Contact Map
3ucpA 1 0.6207 25.8 0.957 Contact Map
4w65A 1 0.4397 15.7 0.961 Contact Map
3pmqA 1 0.5172 15.6 0.961 Contact Map
4n4rB 1 0.5948 15.3 0.961 Contact Map
1yr2A 1 0.7241 13.5 0.962 Contact Map
3k6vA 1 0.4784 10.9 0.964 Contact Map
3b55A 1 0.4353 10.2 0.964 Contact Map
2dgyA 1 0.3664 8.5 0.965 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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