GREMLIN Database
FABA - 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase
UniProt: P0A6Q3 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG10273
Length: 172 (162)
Sequences: 962 (519)
Seq/√Len: 40.8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
9_T12_D4.5491.00
39_R60_D4.1741.00
15_A20_E3.8421.00
122_A150_V3.3391.00
39_R58_E3.2421.00
31_A73_I2.7741.00
126_T152_G2.7451.00
132_K145_D2.6681.00
149_L154_L2.4921.00
128_R147_E2.4221.00
56_E128_R2.3661.00
147_E154_L2.3251.00
126_T149_L2.2821.00
14_L18_R2.1590.99
17_G31_A2.1300.99
54_Y128_R1.9660.99
111_E159_S1.9640.99
87_M146_G1.9560.99
98_L136_N1.9300.99
50_F145_D1.9220.99
18_R73_I1.9200.99
42_K56_E1.9190.99
56_E126_T1.9090.99
100_G136_N1.8980.99
14_L32_P1.8760.98
10_K14_L1.8550.98
128_R149_L1.8390.98
149_L152_G1.8170.98
118_V148_V1.7320.97
150_V153_R1.6870.97
7_S11_E1.6870.97
119_L122_A1.6820.97
94_Y98_L1.6500.96
15_A18_R1.5380.95
107_L164_G1.5330.95
135_V141_M1.5280.94
123_K151_D1.5070.94
87_M129_I1.4510.93
148_V156_Y1.4450.93
36_M90_L1.4340.92
58_E124_K1.4240.92
27_P101_E1.4100.92
95_L142_G1.3990.91
158_A161_L1.3930.91
54_Y130_H1.3900.91
28_Q74_G1.3840.91
130_H145_D1.3800.91
109_V112_V1.3390.89
83_G156_Y1.3190.89
18_R31_A1.2780.87
98_L131_F1.2730.87
125_V148_V1.2540.86
154_L157_T1.2350.85
49_N130_H1.2350.85
75_D105_R1.1960.83
87_M158_A1.1900.83
115_T157_T1.1890.83
32_P39_R1.1820.82
27_P33_N1.1620.81
41_V58_E1.1550.81
21_L93_F1.1510.81
41_V56_E1.1460.80
45_E98_L1.1230.79
71_H77_V1.1220.79
55_V131_F1.0880.77
83_G112_V1.0780.76
130_H147_E1.0610.75
26_G96_G1.0590.75
40_V93_F1.0550.75
116_G153_R1.0410.74
113_K159_S1.0280.73
10_K38_D1.0220.72
33_N37_M1.0170.72
28_Q73_I1.0150.72
43_M97_W1.0010.71
71_H80_G0.9940.70
70_C127_Y0.9840.69
88_W92_G0.9840.69
88_W163_V0.9780.69
59_L65_L0.9640.68
8_Y93_F0.9610.67
100_G140_I0.9570.67
16_S21_L0.9550.67
88_W110_G0.9320.65
84_L88_W0.9300.65
14_L20_E0.9270.65
100_G134_I0.9250.64
69_G73_I0.9160.64
10_K13_L0.9140.63
8_Y21_L0.9100.63
71_H75_D0.9070.63
131_F149_L0.8990.62
10_K32_P0.8930.62
58_E126_T0.8910.61
91_V144_A0.8900.61
147_E157_T0.8800.60
20_E24_A0.8770.60
47_G54_Y0.8720.60
96_G142_G0.8710.60
42_K54_Y0.8610.59
10_K62_N0.8600.59
57_A92_G0.8600.59
122_A153_R0.8580.59
77_V117_Q0.8560.58
131_F144_A0.8430.57
44_T54_Y0.8380.57
70_C77_V0.8220.55
27_P168_D0.8180.55
119_L150_V0.8100.54
132_K143_L0.8100.54
27_P100_G0.8050.54
10_K17_G0.8030.54
47_G51_D0.8020.53
16_S96_G0.7840.52
30_P125_V0.7840.52
91_V94_Y0.7690.50
84_L158_A0.7660.50
84_L156_Y0.7660.50
27_P96_G0.7630.50
34_M82_L0.7580.49
133_R143_L0.7580.49
10_K37_M0.7570.49
75_D114_F0.7560.49
30_P92_G0.7560.49
85_D164_G0.7520.49
126_T141_M0.7490.49
85_D88_W0.7470.48
136_N140_I0.7350.47
59_L125_V0.7350.47
78_M110_G0.7300.47
64_D94_Y0.7290.47
16_S93_F0.7290.47
66_W79_P0.7270.46
28_Q92_G0.7170.46
77_V80_G0.7170.46
62_N65_L0.7160.45
110_G134_I0.7140.45
90_L129_I0.7100.45
31_A146_G0.7090.45
108_G164_G0.7010.44
76_P120_P0.6990.44
105_R166_F0.6980.44
17_G89_Q0.6970.44
88_W108_G0.6930.43
79_P84_L0.6890.43
50_F132_K0.6790.42
39_R141_M0.6770.42
71_H117_Q0.6740.42
138_R152_G0.6720.41
11_E15_A0.6710.41
49_N157_T0.6590.40
48_G63_P0.6580.40
35_L95_L0.6560.40
91_V131_F0.6550.40
30_P161_L0.6490.39
116_G151_D0.6490.39
11_E14_L0.6470.39
77_V86_A0.6420.39
23_G26_G0.6400.39
10_K33_N0.6390.39
128_R154_L0.6350.38
139_L164_G0.6340.38
40_V102_G0.6300.38
40_V124_K0.6300.38
49_N145_D0.6270.37
107_L166_F0.6200.37
10_K157_T0.6200.37
13_L116_G0.6190.37
64_D123_K0.6180.37
115_T166_F0.6140.36
75_D80_G0.6140.36
100_G142_G0.6130.36
95_L106_A0.6110.36
113_K158_A0.6110.36
37_M129_I0.6100.36
68_F120_P0.6090.36
94_Y100_G0.6090.36
62_N69_G0.6060.36
12_D56_E0.6060.36
20_E47_G0.6020.35
45_E94_Y0.5990.35
129_I144_A0.5940.35
80_G83_G0.5920.35
16_S26_G0.5910.34
132_K160_D0.5910.34
8_Y137_R0.5910.34
114_F127_Y0.5900.34
121_T126_T0.5840.34
101_E167_Q0.5820.34
75_D116_G0.5820.34
104_G150_V0.5800.34
49_N124_K0.5800.34
52_K134_I0.5780.33
82_L116_G0.5770.33
38_D66_W0.5760.33
116_G155_I0.5760.33
86_A99_G0.5750.33
64_D99_G0.5750.33
61_I84_L0.5740.33
10_K16_S0.5730.33
121_T153_R0.5690.33
10_K24_A0.5660.32
36_M120_P0.5610.32
143_L162_K0.5600.32
41_V124_K0.5600.32
28_Q100_G0.5590.32
109_V168_D0.5580.32
42_K64_D0.5570.32
60_D88_W0.5540.31
77_V112_V0.5520.31
71_H76_P0.5510.31
52_K118_V0.5500.31
40_V111_E0.5450.31
81_C156_Y0.5420.30
107_L163_V0.5410.30
37_M55_V0.5410.30
36_M129_I0.5360.30
100_G138_R0.5360.30
72_F83_G0.5330.30
153_R168_D0.5330.30
62_N98_L0.5300.30
45_E125_V0.5280.29
104_G163_V0.5270.29
71_H82_L0.5270.29
25_K28_Q0.5250.29
24_A46_T0.5220.29
86_A125_V0.5220.29
67_F156_Y0.5210.29
33_N36_M0.5190.29
72_F80_G0.5170.29
30_P34_M0.5170.29
74_G163_V0.5130.28
17_G91_V0.5110.28
50_F143_L0.5100.28
48_G80_G0.5090.28
65_L78_M0.5070.28
44_T145_D0.5030.27
94_Y132_K0.5020.27
135_V139_L0.5020.27
81_C114_F0.5020.27
7_S12_D0.5010.27
30_P85_D0.5010.27
47_G116_G0.5000.27
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2cf2C 2 0.9942 100 0.401 Contact Map
3q62A 2 0.9826 100 0.446 Contact Map
4b0bA 2 0.9884 100 0.46 Contact Map
2gllA 3 0.8314 99.8 0.624 Contact Map
1u1zA 3 0.8081 99.8 0.64 Contact Map
1z6bA 3 0.8023 99.7 0.67 Contact Map
3d6xA 3 0.7965 99.6 0.7 Contact Map
4h4gA 3 0.8081 99.6 0.708 Contact Map
4i83A 3 0.8081 99.5 0.718 Contact Map
3esiA 4 0.7093 99.2 0.762 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0072 seconds.