ENO - ECOLI - GREMLIN Contacts

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ENO - Enolase

UniProt:	P0A6P9	Sequences: MSKIVKIIGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKSRFLGKGVTKAVAAVNGPIAQALIGKDAKDQAGIDKIMIDLDGTENKSKFGANAILAVSLANAKAAAAAKGMPLYEHIAELNGTPGKYSMPVPMMNIINGGEHADNNVDIQEFMIQPVGAKTVKEAIRMGSEVFHHLAKVLKAKGMNTAVGDEGGYAPNLGSNAEALAVIAEAVKAAGYELGKDITLAMDCAASEFYKDGKYVLAGEGNKAFTSEEFTHFLEELTKQYPIVSIEDGLDESDWDGFAYQTKVLGDKIQLVGDDLFVTNTKILKEGIEKGIANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDRVAKYNQLIRIEEALGEKAPYNGRKEIKGQA	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10258
Length:	432 (416)
Sequences:	3438 (1540)
Seq/√Len:	75.5

ECOLI - ENO
BACSU - ENO
HALSA - ENO
SULSO - ENO

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
329_E	333_K	4.030	1.00
11_E	58_R	3.653	1.00
12_I	36_A	3.606	1.00
338_S	365_T	3.460	1.00
23_A	113_A	3.382	1.00
271_E	303_Y	3.190	1.00
101_E	325_K	3.183	1.00
86_D	89_G	3.076	1.00
278_E	307_V	3.057	1.00
172_Q	244_A	3.046	1.00
74_P	105_K	2.970	1.00
328_K	332_E	2.969	1.00
269_T	272_E	2.871	1.00
46_R	326_I	2.841	1.00
189_V	241_I	2.695	1.00
176_A	185_M	2.672	1.00
358_M	362_A	2.640	1.00
69_A	73_G	2.621	1.00
183_I	410_I	2.604	1.00
153_I	226_I	2.541	1.00
199_A	232_A	2.536	1.00
220_A	283_Q	2.536	1.00
382_D	408_Q	2.519	1.00
29_G	125_A	2.504	1.00
90_I	118_N	2.499	1.00
217_G	221_E	2.489	1.00
236_E	239_K	2.393	1.00
327_L	339_I	2.328	1.00
174_V	242_T	2.286	1.00
116_L	349_L	2.276	1.00
190_F	398_S	2.258	1.00
223_L	227_A	2.249	1.00
408_Q	411_R	2.246	1.00
302_A	306_K	2.235	1.00
179_V	183_I	2.232	1.00
88_A	354_A	2.198	1.00
200_K	228_E	2.195	1.00
231_K	236_E	2.156	1.00
353_L	387_T	2.134	1.00
45_S	296_S	2.112	1.00
82_K	93_I	2.071	1.00
320_F	336_A	2.067	1.00
46_R	296_S	2.067	1.00
368_I	389_A	2.064	1.00
313_Q	391_Q	2.046	1.00
92_K	96_D	2.030	1.00
73_G	77_Q	2.010	1.00
320_F	330_G	1.983	1.00
120_K	379_T	1.976	1.00
276_F	280_L	1.963	1.00
131_Y	415_A	1.961	1.00
275_H	307_V	1.946	1.00
27_L	84_A	1.906	1.00
10_R	414_E	1.903	1.00
75_I	97_L	1.896	1.00
227_A	237_L	1.873	1.00
151_M	186_G	1.867	1.00
224_A	284_Y	1.863	1.00
22_E	411_R	1.856	1.00
296_S	326_I	1.828	1.00
181_E	184_R	1.826	1.00
34_M	408_Q	1.800	1.00
274_T	293_L	1.799	1.00
274_T	303_Y	1.784	1.00
259_V	267_A	1.782	1.00
7_I	79_L	1.765	1.00
190_F	396_S	1.745	1.00
24_E	34_M	1.725	1.00
60_L	192_H	1.709	1.00
10_R	22_E	1.707	1.00
282_K	311_K	1.694	1.00
230_V	243_L	1.669	1.00
247_C	277_L	1.654	1.00
279_E	283_Q	1.654	1.00
190_F	397_M	1.649	1.00
185_M	241_I	1.647	1.00
200_K	225_V	1.625	1.00
292_G	304_Q	1.617	1.00
257_K	267_A	1.608	1.00
179_V	410_I	1.608	1.00
49_L	104_S	1.594	0.99
8_I	414_E	1.588	0.99
45_S	250_S	1.560	0.99
356_I	368_I	1.558	0.99
228_E	231_K	1.555	0.99
273_F	277_L	1.553	0.99
278_E	282_K	1.532	0.99
244_A	288_S	1.531	0.99
356_I	387_T	1.519	0.99
327_L	355_A	1.511	0.99
242_T	287_V	1.493	0.99
270_S	300_G	1.488	0.99
357_K	361_D	1.488	0.99
268_F	273_F	1.481	0.99
97_L	106_F	1.481	0.99
119_A	349_L	1.460	0.99
82_K	89_G	1.459	0.99
11_E	180_K	1.443	0.99
66_K	69_A	1.426	0.99
260_L	268_F	1.420	0.99
302_A	335_I	1.418	0.99
36_A	375_T	1.416	0.99
22_E	408_Q	1.408	0.99
88_A	350_T	1.405	0.99
184_R	188_E	1.385	0.99
134_I	386_G	1.383	0.99
195_K	198_K	1.382	0.98
376_E	404_A	1.379	0.98
368_I	384_A	1.372	0.98
357_K	360_K	1.363	0.98
24_E	411_R	1.359	0.98
379_T	383_L	1.350	0.98
194_A	212_Y	1.346	0.98
11_E	63_G	1.341	0.98
51_L	66_K	1.336	0.98
75_I	114_V	1.333	0.98
275_H	278_E	1.329	0.98
272_E	275_H	1.314	0.98
74_P	77_Q	1.312	0.98
292_G	314_L	1.310	0.98
230_V	237_L	1.309	0.98
89_G	93_I	1.307	0.98
134_I	353_L	1.295	0.98
304_Q	308_L	1.289	0.98
177_K	185_M	1.285	0.98
328_K	358_M	1.283	0.98
220_A	224_A	1.275	0.97
335_I	364_Y	1.266	0.97
111_I	348_S	1.257	0.97
37_A	113_A	1.253	0.97
25_V	118_N	1.248	0.97
343_F	349_L	1.245	0.97
169_F	222_A	1.244	0.97
3_K	28_E	1.241	0.97
150_M	172_Q	1.234	0.97
70_A	74_P	1.233	0.97
206_V	398_S	1.229	0.97
129_P	132_E	1.220	0.97
75_I	106_F	1.218	0.97
94_M	348_S	1.217	0.97
400_S	403_V	1.216	0.97
12_I	375_T	1.209	0.96
324_T	355_A	1.208	0.96
308_L	312_I	1.201	0.96
10_R	24_E	1.199	0.96
320_F	364_Y	1.194	0.96
341_I	356_I	1.193	0.96
26_H	32_V	1.192	0.96
297_D	300_G	1.187	0.96
34_M	411_R	1.169	0.96
88_A	144_Y	1.169	0.96
396_S	403_V	1.167	0.96
301_F	314_L	1.166	0.96
195_K	199_A	1.165	0.96
324_T	358_M	1.160	0.96
225_V	228_E	1.159	0.96
88_A	92_K	1.154	0.95
343_F	383_L	1.154	0.95
250_S	294_D	1.150	0.95
299_D	333_K	1.149	0.95
150_M	367_V	1.148	0.95
13_I	59_F	1.148	0.95
84_A	118_N	1.141	0.95
162_N	215_N	1.138	0.95
6_K	76_A	1.135	0.95
353_L	383_L	1.134	0.95
85_K	126_K	1.133	0.95
196_V	225_V	1.133	0.95
334_G	364_Y	1.133	0.95
27_L	31_F	1.128	0.95
119_A	134_I	1.123	0.95
79_L	82_K	1.123	0.95
260_L	264_G	1.122	0.95
273_F	293_L	1.107	0.94
304_Q	314_L	1.106	0.94
228_E	232_A	1.106	0.94
71_V	113_A	1.105	0.94
24_E	414_E	1.096	0.94
22_E	34_M	1.090	0.94
51_L	70_A	1.086	0.94
103_K	351_E	1.079	0.93
136_E	143_K	1.072	0.93
76_A	80_I	1.071	0.93
262_G	265_N	1.069	0.93
302_A	333_K	1.063	0.93
84_A	122_A	1.063	0.93
163_N	219_N	1.062	0.93
275_H	279_E	1.060	0.93
279_E	282_K	1.059	0.93
31_F	125_A	1.057	0.93
87_Q	133_H	1.054	0.93
166_I	247_C	1.054	0.93
265_N	268_F	1.053	0.93
417_G	420_A	1.053	0.93
260_L	273_F	1.050	0.92
303_Y	306_K	1.044	0.92
182_A	422_Y	1.041	0.92
177_K	181_E	1.036	0.92
298_W	335_I	1.035	0.92
58_R	63_G	1.025	0.92
185_M	235_Y	1.019	0.91
306_K	334_G	1.018	0.91
231_K	237_L	1.018	0.91
78_A	97_L	1.015	0.91
288_S	313_Q	1.013	0.91
93_I	96_D	1.013	0.91
192_H	195_K	1.010	0.91
10_R	411_R	1.005	0.91
356_I	360_K	1.003	0.91
195_K	232_A	1.003	0.91
260_L	263_E	1.000	0.91
94_M	111_I	1.000	0.91
281_T	308_L	0.999	0.90
128_M	133_H	0.999	0.90
128_M	136_E	0.998	0.90
192_H	232_A	0.997	0.90
293_L	300_G	0.992	0.90
305_T	364_Y	0.984	0.90
326_I	335_I	0.983	0.90
68_V	72_N	0.982	0.90
166_I	280_L	0.981	0.90
324_T	354_A	0.980	0.90
145_S	423_N	0.977	0.89
8_I	26_H	0.974	0.89
135_A	143_K	0.970	0.89
200_K	221_E	0.969	0.89
35_A	116_L	0.964	0.89
366_A	389_A	0.963	0.89
326_I	329_E	0.961	0.89
79_L	118_N	0.959	0.89
327_L	364_Y	0.958	0.89
411_R	414_E	0.956	0.88
55_D	58_R	0.952	0.88
154_I	164_V	0.951	0.88
172_Q	367_V	0.950	0.88
360_K	366_A	0.944	0.88
397_M	403_V	0.943	0.88
303_Y	307_V	0.936	0.87
27_L	30_G	0.932	0.87
120_K	378_A	0.930	0.87
100_T	105_K	0.925	0.87
31_F	124_A	0.923	0.87
356_I	366_A	0.922	0.87
9_G	71_V	0.919	0.86
163_N	216_L	0.919	0.86
126_K	136_E	0.918	0.86
49_L	102_N	0.917	0.86
129_P	415_A	0.916	0.86
220_A	279_E	0.915	0.86
188_E	235_Y	0.913	0.86
10_R	34_M	0.911	0.86
116_L	353_L	0.911	0.86
219_N	280_L	0.908	0.86
336_A	364_Y	0.907	0.86
376_E	400_S	0.904	0.86
255_D	267_A	0.902	0.85
74_P	78_A	0.899	0.85
23_A	71_V	0.892	0.85
185_M	240_D	0.890	0.85
281_T	312_I	0.887	0.84
330_G	336_A	0.882	0.84
164_V	219_N	0.880	0.84
92_K	354_A	0.878	0.84
176_A	240_D	0.876	0.84
249_A	252_F	0.871	0.83
196_V	228_E	0.870	0.83
166_I	276_F	0.868	0.83
25_V	33_G	0.868	0.83
65_T	180_K	0.864	0.83
182_A	186_G	0.862	0.83
257_K	269_T	0.861	0.83
134_I	137_L	0.859	0.82
134_I	379_T	0.858	0.82
331_I	362_A	0.858	0.82
161_D	198_K	0.857	0.82
319_L	326_I	0.856	0.82
46_R	329_E	0.855	0.82
271_E	274_T	0.853	0.82
163_N	215_N	0.852	0.82
254_K	259_V	0.851	0.82
144_Y	388_A	0.851	0.82
6_K	26_H	0.845	0.81
78_A	93_I	0.844	0.81
280_L	286_I	0.842	0.81
288_S	391_Q	0.841	0.81
161_D	194_A	0.833	0.80
327_L	359_A	0.832	0.80
277_L	289_I	0.829	0.80
258_Y	262_G	0.827	0.80
172_Q	242_T	0.826	0.80
5_V	28_E	0.822	0.80
339_I	359_A	0.816	0.79
24_E	32_V	0.816	0.79
218_S	221_E	0.814	0.79
178_T	413_E	0.814	0.79
10_R	408_Q	0.814	0.79
55_D	65_T	0.813	0.79
178_T	181_E	0.812	0.79
271_E	275_H	0.810	0.79
293_L	304_Q	0.809	0.79
254_K	257_K	0.802	0.78
85_K	125_A	0.801	0.78
255_D	259_V	0.799	0.78
196_V	232_A	0.798	0.78
202_M	205_A	0.798	0.78
378_A	400_S	0.795	0.77
341_I	352_T	0.795	0.77
72_N	77_Q	0.795	0.77
148_V	422_Y	0.794	0.77
180_K	413_E	0.793	0.77
254_K	258_Y	0.791	0.77
349_L	379_T	0.788	0.77
116_L	120_K	0.788	0.77
216_L	222_A	0.787	0.77
138_N	354_A	0.787	0.77
384_A	392_I	0.785	0.76
227_A	230_V	0.784	0.76
116_L	379_T	0.782	0.76
133_H	136_E	0.782	0.76
170_M	315_V	0.780	0.76
378_A	403_V	0.779	0.76
8_I	72_N	0.779	0.76
101_E	104_S	0.779	0.76
18_N	191_H	0.778	0.76
177_K	184_R	0.778	0.76
223_L	245_M	0.774	0.75
13_I	183_I	0.771	0.75
224_A	227_A	0.766	0.75
138_N	144_Y	0.766	0.75
70_A	106_F	0.765	0.75
163_N	166_I	0.764	0.74
202_M	217_G	0.762	0.74
323_N	346_I	0.760	0.74
353_L	389_A	0.758	0.74
274_T	304_Q	0.754	0.73
166_I	219_N	0.753	0.73
158_E	251_E	0.749	0.73
132_E	415_A	0.748	0.73
135_A	144_Y	0.745	0.73
329_E	332_E	0.744	0.72
216_L	225_V	0.743	0.72
137_L	353_L	0.743	0.72
82_K	90_I	0.740	0.72
278_E	281_T	0.739	0.72
58_R	184_R	0.737	0.72
108_A	112_L	0.734	0.71
236_E	240_D	0.733	0.71
93_I	97_L	0.732	0.71
221_E	224_A	0.731	0.71
339_I	355_A	0.727	0.71
49_L	95_I	0.727	0.71
274_T	307_V	0.727	0.71
247_C	289_I	0.726	0.71
153_I	189_V	0.726	0.71
163_N	218_S	0.724	0.70
408_Q	414_E	0.723	0.70
349_L	383_L	0.723	0.70
164_V	215_N	0.723	0.70
95_I	348_S	0.723	0.70
7_I	76_A	0.721	0.70
144_Y	354_A	0.720	0.70
293_L	308_L	0.718	0.70
360_K	388_A	0.718	0.70
27_L	32_V	0.717	0.70
148_V	424_G	0.717	0.70
190_F	206_V	0.716	0.70
163_N	217_G	0.716	0.70
180_K	414_E	0.714	0.69
24_E	408_Q	0.714	0.69
120_K	124_A	0.711	0.69
262_G	280_L	0.710	0.69
158_E	247_C	0.708	0.69
247_C	252_F	0.707	0.69
79_L	90_I	0.707	0.69
278_E	311_K	0.707	0.69
187_S	397_M	0.707	0.69
161_D	164_V	0.704	0.68
252_F	277_L	0.703	0.68
166_I	245_M	0.703	0.68
183_I	187_S	0.702	0.68
145_S	388_A	0.699	0.68
158_E	198_K	0.698	0.68
270_S	293_L	0.698	0.68
24_E	36_A	0.697	0.68
7_I	25_V	0.696	0.67
13_I	184_R	0.695	0.67
247_C	294_D	0.695	0.67
366_A	387_T	0.693	0.67
27_L	125_A	0.689	0.67
226_I	243_L	0.687	0.66
21_V	71_V	0.686	0.66
37_A	112_L	0.686	0.66
11_E	65_T	0.685	0.66
171_I	189_V	0.681	0.66
355_A	366_A	0.677	0.65
154_I	226_I	0.677	0.65
134_I	368_I	0.674	0.65
276_F	279_E	0.674	0.65
220_A	284_Y	0.673	0.65
237_L	243_L	0.673	0.65
161_D	203_N	0.673	0.65
171_I	241_I	0.673	0.65
277_L	304_Q	0.672	0.65
343_F	352_T	0.671	0.65
227_A	284_Y	0.670	0.64
33_G	124_A	0.670	0.64
189_V	192_H	0.669	0.64
79_L	93_I	0.669	0.64
45_S	326_I	0.667	0.64
180_K	183_I	0.667	0.64
45_S	294_D	0.666	0.64
60_L	187_S	0.665	0.64
270_S	274_T	0.664	0.64
136_E	388_A	0.662	0.64
281_T	304_Q	0.662	0.64
292_G	301_F	0.661	0.63
338_S	367_V	0.661	0.63
249_A	294_D	0.661	0.63
274_T	308_L	0.659	0.63
253_Y	294_D	0.658	0.63
171_I	226_I	0.657	0.63
6_K	80_I	0.656	0.63
59_F	191_H	0.652	0.62
45_S	295_E	0.651	0.62
247_C	273_F	0.646	0.62
153_I	171_I	0.646	0.62
243_L	247_C	0.642	0.61
325_K	329_E	0.641	0.61
145_S	421_P	0.638	0.61
302_A	334_G	0.638	0.61
299_D	302_A	0.637	0.61
33_G	121_A	0.635	0.60
105_K	348_S	0.634	0.60
85_K	122_A	0.634	0.60
324_T	328_K	0.634	0.60
128_M	132_E	0.634	0.60
28_E	84_A	0.634	0.60
166_I	222_A	0.633	0.60
331_I	358_M	0.632	0.60
314_L	335_I	0.630	0.60
119_A	379_T	0.628	0.59
85_K	118_N	0.628	0.59
202_M	221_E	0.627	0.59
251_E	394_T	0.627	0.59
249_A	277_L	0.626	0.59
275_H	303_Y	0.625	0.59
21_V	113_A	0.625	0.59
8_I	24_E	0.624	0.59
90_I	95_I	0.624	0.59
58_R	180_K	0.624	0.59
29_G	84_A	0.623	0.59
168_E	370_H	0.623	0.59
368_I	383_L	0.623	0.59
122_A	133_H	0.622	0.59
186_G	241_I	0.622	0.59
227_A	243_L	0.621	0.59
95_I	103_K	0.619	0.58
161_D	197_L	0.619	0.58
165_D	259_V	0.619	0.58
118_N	122_A	0.616	0.58
207_G	370_H	0.614	0.58
305_T	334_G	0.613	0.58
89_G	92_K	0.613	0.58
11_E	187_S	0.611	0.57
151_M	397_M	0.611	0.57
354_A	357_K	0.609	0.57
29_G	32_V	0.609	0.57
368_I	387_T	0.608	0.57
84_A	90_I	0.606	0.57
12_I	34_M	0.606	0.57
31_F	84_A	0.603	0.56
9_G	21_V	0.603	0.56
144_Y	357_K	0.603	0.56
92_K	350_T	0.602	0.56
103_K	111_I	0.601	0.56
46_R	294_D	0.601	0.56
332_E	358_M	0.600	0.56
313_Q	390_G	0.600	0.56
268_F	272_E	0.600	0.56
170_M	244_A	0.599	0.56
83_D	122_A	0.598	0.56
68_V	71_V	0.597	0.56
313_Q	367_V	0.594	0.55
216_L	219_N	0.594	0.55
158_E	294_D	0.594	0.55
184_R	235_Y	0.592	0.55
27_L	121_A	0.591	0.55
252_F	260_L	0.591	0.55
25_V	117_A	0.590	0.55
78_A	82_K	0.589	0.55
12_I	21_V	0.589	0.55
319_L	335_I	0.588	0.55
271_E	299_D	0.587	0.54
320_F	335_I	0.587	0.54
40_G	44_G	0.585	0.54
22_E	414_E	0.579	0.53
29_G	127_G	0.578	0.53
278_E	308_L	0.578	0.53
333_K	364_Y	0.576	0.53
169_F	216_L	0.576	0.53
70_A	110_A	0.575	0.53
144_Y	421_P	0.574	0.53
176_A	182_A	0.574	0.53
197_L	225_V	0.573	0.53
150_M	244_A	0.573	0.53
296_S	329_E	0.573	0.53
3_K	127_G	0.572	0.53
13_I	397_M	0.570	0.52
154_I	225_V	0.569	0.52
72_N	76_A	0.569	0.52
176_A	183_I	0.569	0.52
180_K	410_I	0.569	0.52
162_N	212_Y	0.567	0.52
298_W	329_E	0.567	0.52
36_A	414_E	0.566	0.52
172_Q	186_G	0.565	0.52
128_M	137_L	0.565	0.52
136_E	144_Y	0.565	0.52
124_A	127_G	0.564	0.52
263_E	268_F	0.563	0.51
376_E	392_I	0.562	0.51
65_T	69_A	0.562	0.51
152_N	155_N	0.562	0.51
164_V	182_A	0.559	0.51
143_K	388_A	0.558	0.51
35_A	117_A	0.557	0.51
219_N	260_L	0.557	0.51
154_I	166_I	0.555	0.50
138_N	388_A	0.555	0.50
301_F	336_A	0.554	0.50
84_A	125_A	0.553	0.50
356_I	389_A	0.553	0.50
58_R	65_T	0.552	0.50
143_K	146_M	0.551	0.50
161_D	205_A	0.551	0.50
341_I	368_I	0.549	0.50
339_I	364_Y	0.548	0.50
23_A	114_V	0.548	0.50
163_N	202_M	0.548	0.50
292_G	335_I	0.547	0.49
7_I	24_E	0.547	0.49
196_V	200_K	0.546	0.49
406_Y	409_L	0.546	0.49
32_V	124_A	0.545	0.49
42_S	47_E	0.545	0.49
159_H	370_H	0.545	0.49
353_L	357_K	0.544	0.49
277_L	280_L	0.544	0.49
12_I	376_E	0.543	0.49
202_M	225_V	0.543	0.49
418_E	421_P	0.541	0.49
243_L	286_I	0.541	0.49
22_E	36_A	0.541	0.49
251_E	321_V	0.541	0.49
193_L	207_G	0.540	0.49
83_D	86_D	0.540	0.49
5_V	26_H	0.539	0.48
94_M	106_F	0.539	0.48
162_N	221_E	0.537	0.48
88_A	419_K	0.537	0.48
11_E	59_F	0.533	0.48
155_N	168_E	0.533	0.48
132_E	136_E	0.533	0.48
163_N	205_A	0.532	0.47
196_V	229_A	0.532	0.47
83_D	125_A	0.531	0.47
119_A	386_G	0.531	0.47
175_G	185_M	0.531	0.47
163_N	262_G	0.530	0.47
23_A	118_N	0.530	0.47
21_V	376_E	0.529	0.47
275_H	282_K	0.529	0.47
132_E	419_K	0.528	0.47
380_I	383_L	0.528	0.47
221_E	225_V	0.527	0.47
3_K	83_D	0.527	0.47
219_N	247_C	0.527	0.47
172_Q	247_C	0.526	0.47
137_L	361_D	0.525	0.47
88_A	138_N	0.524	0.46
163_N	225_V	0.522	0.46
199_A	228_E	0.522	0.46
13_I	187_S	0.521	0.46
281_T	311_K	0.521	0.46
327_L	341_I	0.521	0.46
88_A	357_K	0.519	0.46
416_L	420_A	0.519	0.46
251_E	383_L	0.518	0.46
383_L	389_A	0.518	0.46
74_P	106_F	0.518	0.46
324_T	327_L	0.517	0.46
159_H	209_E	0.516	0.45
28_E	83_D	0.515	0.45
162_N	262_G	0.514	0.45
144_Y	350_T	0.512	0.45
261_A	265_N	0.512	0.45
215_N	219_N	0.512	0.45
305_T	309_G	0.512	0.45
149_P	182_A	0.511	0.45
162_N	204_T	0.511	0.45
28_E	80_I	0.511	0.45
132_E	145_S	0.511	0.45
343_F	368_I	0.511	0.45
155_N	207_G	0.509	0.45
155_N	370_H	0.509	0.45
168_E	207_G	0.509	0.45
189_V	242_T	0.508	0.44
301_F	304_Q	0.508	0.44
34_M	414_E	0.508	0.44
5_V	9_G	0.507	0.44
176_A	181_E	0.507	0.44
219_N	252_F	0.507	0.44
252_F	262_G	0.506	0.44
67_A	110_A	0.505	0.44
137_L	386_G	0.505	0.44
26_H	31_F	0.505	0.44
300_G	308_L	0.502	0.44
158_E	252_F	0.502	0.44
150_M	243_L	0.502	0.44
126_K	137_L	0.501	0.44
277_L	293_L	0.501	0.44
203_N	215_N	0.500	0.44
172_Q	287_V	0.500	0.44
7_I	94_M	0.500	0.44

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4mksA	3	0.919	100	0.284	Contact Map
1w6tA	3	0.9815	100	0.309	Contact Map
3tqpA	2	0.9653	100	0.321	Contact Map
3otrA	2	0.9931	100	0.324	Contact Map
2akzA	2	0.9815	100	0.326	Contact Map
4ywsA	2	0.9491	100	0.346	Contact Map
2fymA	3	0.9977	100	0.349	Contact Map
4ropA	3	0.9792	100	0.35	Contact Map
2pa6A	5	0.9676	100	0.352	Contact Map
3uj2A	3	0.9722	100	0.353	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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