GREMLIN Database
EFG - Elongation factor G
UniProt: P0A6M8 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG10360
Length: 704 (680)
Sequences: 5369 (2715)
Seq/√Len: 104.1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
377_V383_A5.7161.00
554_D558_Q4.0181.00
500_D521_D3.8921.00
502_E517_H3.7881.00
496_Q609_K3.6031.00
534_Y554_D3.5911.00
523_Y575_G3.4921.00
188_M215_A3.4881.00
236_K247_E3.4321.00
140_F269_A3.3071.00
522_M576_I3.2321.00
116_V146_R3.1811.00
265_T281_A3.1591.00
310_H315_E3.0081.00
623_T678_A2.9301.00
495_R689_E2.9231.00
559_E594_K2.9151.00
336_F385_A2.9131.00
344_N376_E2.8981.00
140_F267_G2.8851.00
249_K284_D2.8841.00
618_K683_E2.8381.00
114_C117_G2.8121.00
603_E607_K2.7931.00
50_M68_T2.7851.00
321_A334_T2.7511.00
169_L265_T2.6991.00
539_D577_R2.6841.00
523_Y577_R2.6601.00
27_T86_I2.6521.00
521_D579_H2.6411.00
113_Y123_S2.6111.00
212_V216_N2.5931.00
571_V605_F2.5931.00
434_A473_M2.5811.00
244_T247_E2.5801.00
497_K523_Y2.4981.00
214_L217_E2.4971.00
552_A590_E2.4901.00
189_K204_Y2.4891.00
445_F458_I2.4801.00
634_D666_Y2.4351.00
417_S459_A2.4101.00
500_D579_H2.4031.00
520_I600_A2.3881.00
528_G573_D2.3731.00
209_A212_V2.3531.00
338_V377_V2.3481.00
590_E594_K2.3411.00
647_S652_V2.3201.00
537_I575_G2.3191.00
187_K245_E2.3041.00
156_N160_T2.2981.00
690_A698_V2.2831.00
533_G573_D2.2471.00
332_N440_K2.2171.00
183_V211_M2.1511.00
423_K480_E2.1321.00
535_E575_G2.1281.00
526_E529_S2.1221.00
657_E686_K2.1061.00
230_S254_Q2.0691.00
235_E239_G2.0611.00
521_D577_R2.0601.00
153_K157_Q2.0561.00
115_A144_M2.0471.00
534_Y558_Q2.0391.00
73_S81_P2.0341.00
690_A694_V2.0301.00
296_N306_P2.0131.00
152_L214_L2.0121.00
352_S398_C2.0081.00
317_F349_V2.0061.00
519_V579_H1.9911.00
635_L640_G1.9841.00
517_H582_S1.9801.00
445_F469_I1.9701.00
423_K482_N1.9681.00
504_K515_Y1.9651.00
641_M688_D1.9641.00
474_K480_E1.9631.00
16_S111_M1.9591.00
300_D303_K1.9561.00
527_P573_D1.9541.00
528_G533_G1.9441.00
139_A158_I1.9411.00
621_V635_L1.9241.00
13_I84_I1.9031.00
309_R315_E1.9001.00
336_F383_A1.8941.00
214_L218_W1.8841.00
413_E446_R1.8501.00
521_D539_D1.8441.00
540_I544_V1.8361.00
342_V376_E1.8271.00
167_V261_I1.8121.00
338_V383_A1.8101.00
620_E653_K1.8071.00
194_N203_E1.8071.00
217_E221_N1.8051.00
171_L211_M1.7861.00
191_I277_A1.7771.00
189_K206_D1.7771.00
684_F687_Y1.7351.00
43_V48_A1.7301.00
557_I597_A1.7281.00
439_A445_F1.7181.00
243_L251_A1.7171.00
618_K655_H1.7121.00
154_V157_Q1.7051.00
561_L574_M1.6931.00
601_F605_F1.6881.00
159_K221_N1.6861.00
497_K521_D1.6801.00
223_I248_I1.6791.00
34_T70_A1.6711.00
520_I557_I1.6701.00
307_A404_I1.6671.00
188_M216_N1.6651.00
218_W221_N1.6651.00
421_E482_N1.6651.00
187_K204_Y1.6621.00
354_K392_T1.6441.00
294_A297_G1.6241.00
312_S315_E1.6191.00
692_S696_Q1.6061.00
495_R609_K1.5931.00
589_S592_A1.5851.00
232_E235_E1.5851.00
502_E519_V1.5841.00
525_L529_S1.5601.00
52_W64_T1.5591.00
500_D519_V1.5551.00
365_Q374_I1.5521.00
226_A229_A1.5461.00
356_A390_D1.5411.00
534_Y561_L1.5401.00
222_L226_A1.5371.00
16_S109_A1.5351.00
138_I286_L1.5311.00
557_I576_I1.5301.00
657_E685_L1.5281.00
344_N347_D1.5241.00
37_N49_T1.5241.00
504_K517_H1.5231.00
646_E655_H1.5171.00
152_L218_W1.5161.00
68_T367_H1.5151.00
619_V663_M1.5151.00
388_L391_V1.5131.00
618_K685_L1.5131.00
226_A255_R1.4991.00
207_I215_A1.4961.00
448_W459_A1.4811.00
363_I385_A1.4811.00
236_K244_T1.4741.00
522_M604_G1.4731.00
498_V608_A1.4731.00
192_N205_E1.4731.00
231_E235_E1.4701.00
236_K241_E1.4541.00
293_P297_G1.4451.00
350_L403_P1.4431.00
345_S375_K1.4381.00
301_D305_T1.4381.00
65_S87_I1.4361.00
648_E651_G1.4351.00
611_V689_E1.4331.00
126_V129_Q1.4301.00
114_C154_V1.4291.00
9_R82_H1.4271.00
319_A336_F1.4271.00
155_V168_P1.4241.00
571_V601_F1.4221.00
196_A200_V1.4211.00
250_G254_Q1.4171.00
190_A208_P1.4091.00
115_A141_V1.4031.00
561_L601_F1.4031.00
452_E491_R1.4021.00
300_D307_A1.4011.00
498_V501_V1.4001.00
194_N201_T1.4001.00
343_V360_F1.4001.00
374_I377_V1.3961.00
417_S457_I1.3931.00
188_M207_I1.3891.00
625_E652_V1.3861.00
503_G516_G1.3831.00
321_A391_V1.3811.00
231_E260_E1.3791.00
603_E606_K1.3751.00
490_Y661_S1.3701.00
70_A86_I1.3701.00
353_V395_D1.3661.00
152_L171_L1.3641.00
503_G599_I1.3621.00
527_P533_G1.3590.99
643_K657_E1.3590.99
113_Y158_I1.3550.99
131_N137_R1.3520.99
97_I444_S1.3510.99
50_M66_A1.3500.99
350_L355_A1.3490.99
206_D209_A1.3480.99
553_V578_L1.3440.99
254_Q258_N1.3380.99
495_R611_V1.3340.99
82_H283_I1.3340.99
12_N85_N1.3310.99
318_S406_L1.3310.99
470_V483_V1.3280.99
226_A233_L1.3240.99
15_I27_T1.3230.99
14_G106_L1.3230.99
424_T427_D1.3210.99
545_I578_L1.3160.99
537_I577_R1.3140.99
631_V674_T1.3120.99
124_E677_R1.3070.99
249_K285_Y1.3060.99
418_I483_V1.3000.99
695_A699_I1.2970.99
191_I204_Y1.2790.99
37_N40_I1.2780.99
342_V378_R1.2760.99
309_R404_I1.2740.99
26_T269_A1.2710.99
501_V603_E1.2700.99
471_D475_R1.2670.99
458_I469_I1.2630.99
113_Y139_A1.2590.99
645_Q652_V1.2570.99
9_R81_P1.2440.99
439_A458_I1.2440.99
194_N197_D1.2360.99
648_E653_K1.2290.99
216_N220_Q1.2280.99
628_T654_I1.2230.99
362_R373_E1.2230.99
123_S139_A1.2200.99
219_H223_I1.2170.99
431_M473_M1.2110.99
171_L218_W1.2100.99
114_C157_Q1.2100.99
171_L215_A1.2060.99
503_G506_A1.2060.99
669_Q673_L1.2050.99
185_L188_M1.2050.99
169_L281_A1.1910.99
158_I264_V1.1910.99
612_L698_V1.1910.99
529_S535_E1.1890.99
26_T112_V1.1890.99
48_A57_Q1.1850.99
72_W280_D1.1830.99
463_E665_G1.1790.99
618_K657_E1.1740.99
180_T192_N1.1720.98
358_E391_V1.1720.98
574_M601_F1.1720.98
332_N444_S1.1720.98
674_T678_A1.1710.98
525_L535_E1.1690.98
173_I183_V1.1670.98
114_C146_R1.1640.98
26_T278_M1.1630.98
349_V360_F1.1560.98
52_W325_A1.1520.98
317_F343_V1.1480.98
450_D453_S1.1470.98
213_E216_N1.1460.98
635_L658_V1.1390.98
173_I190_A1.1350.98
27_T50_M1.1310.98
111_M139_A1.1310.98
663_M682_M1.1230.98
632_I636_S1.1220.98
620_E655_H1.1210.98
525_L573_D1.1180.98
11_R289_P1.1130.98
211_M214_L1.1120.98
142_N269_A1.1120.98
518_V545_I1.1110.98
317_F338_V1.1050.98
173_I211_M1.1040.98
186_V285_Y1.1010.98
494_I610_P1.0970.98
538_N541_K1.0940.98
546_P583_Y1.0930.98
108_G286_L1.0910.98
213_E217_E1.0890.98
227_A251_A1.0860.98
155_V264_V1.0850.98
71_F83_R1.0830.97
197_D201_T1.0800.97
536_F578_L1.0800.97
566_L699_I1.0800.97
117_G157_Q1.0770.97
55_Q471_D1.0770.97
501_V604_G1.0760.97
538_N547_G1.0750.97
377_V385_A1.0710.97
364_V373_E1.0670.97
525_L528_G1.0640.97
617_M660_L1.0620.97
17_A21_A1.0570.97
598_S602_K1.0560.97
231_E234_M1.0520.97
58_E475_R1.0520.97
670_L674_T1.0510.97
336_F343_V1.0500.97
508_Q513_G1.0480.97
187_K249_K1.0470.97
288_S291_D1.0460.97
399_D402_A1.0450.97
50_M62_T1.0420.97
296_N308_E1.0410.97
325_A335_F1.0410.97
538_N550_I1.0400.97
336_F377_V1.0400.97
540_I543_G1.0390.97
16_S103_M1.0380.97
245_E249_K1.0340.97
253_R291_D1.0330.97
512_R589_S1.0320.97
156_N159_K1.0300.97
243_L247_E1.0260.97
595_L598_S1.0220.96
529_S573_D1.0160.96
100_E132_K1.0130.96
639_R662_E1.0130.96
152_L156_N1.0090.96
525_L575_G1.0090.96
83_R365_Q1.0060.96
33_Y276_Q1.0050.96
318_S340_S1.0020.96
472_R476_E1.0020.96
614_E639_R0.9990.96
631_V670_L0.9990.96
282_V286_L0.9980.96
619_V656_A0.9970.96
539_D579_H0.9960.96
628_T645_Q0.9940.96
343_V349_V0.9900.96
351_N391_V0.9900.96
516_G582_S0.9900.96
144_M175_A0.9890.96
10_Y83_R0.9840.96
623_T631_V0.9820.96
111_M123_S0.9810.95
621_V658_V0.9800.95
503_G519_V0.9780.95
167_V222_L0.9780.95
522_M557_I0.9780.95
617_M682_M0.9770.95
130_A137_R0.9770.95
132_K410_E0.9760.95
151_F168_P0.9720.95
622_E653_K0.9680.95
494_I605_F0.9670.95
501_V607_K0.9650.95
505_H599_I0.9640.95
141_V154_V0.9620.95
157_Q161_R0.9620.95
228_E234_M0.9610.95
630_D645_Q0.9610.95
211_M215_A0.9600.95
612_L695_A0.9600.95
313_D342_V0.9570.95
421_E484_G0.9520.95
544_V580_F0.9490.95
73_S284_D0.9490.95
601_F610_P0.9480.95
30_I70_A0.9460.95
421_E455_Q0.9450.94
107_D337_R0.9440.94
191_I202_F0.9410.94
139_A262_I0.9400.94
144_M149_A0.9360.94
634_D673_L0.9360.94
185_L219_H0.9360.94
658_V666_Y0.9350.94
144_M179_F0.9330.94
100_E129_Q0.9330.94
550_I578_L0.9300.94
226_A248_I0.9290.94
438_L473_M0.9290.94
558_Q562_K0.9280.94
224_E228_E0.9280.94
641_M657_E0.9240.94
292_V297_G0.9230.94
165_N225_S0.9220.94
504_K582_S0.9210.94
243_L248_I0.9200.94
455_Q484_G0.9180.94
292_V295_I0.9150.93
59_R471_D0.9140.93
196_A202_F0.9140.93
518_V597_A0.9130.93
83_R381_D0.9130.93
111_M126_V0.9110.93
119_V123_S0.9110.93
42_E45_D0.9100.93
591_L595_L0.9090.93
503_G507_K0.9090.93
232_E236_K0.9080.93
246_A250_G0.9050.93
519_V580_F0.9020.93
253_R257_L0.9010.93
335_F366_M0.8970.93
228_E233_L0.8960.93
227_A243_L0.8960.93
505_H512_R0.8960.93
297_G309_R0.8950.93
634_D638_R0.8950.93
364_V386_I0.8940.93
552_A594_K0.8880.92
581_G584_H0.8870.92
186_V248_I0.8840.92
180_T210_D0.8830.92
193_W202_F0.8820.92
25_T43_V0.8800.92
53_M64_T0.8790.92
571_V574_M0.8790.92
300_D305_T0.8770.92
97_I411_F0.8760.92
513_G587_D0.8750.92
635_L654_I0.8750.92
560_Q601_F0.8700.92
374_I383_A0.8700.92
545_I550_I0.8680.92
584_H587_D0.8670.92
185_L215_A0.8660.91
52_W369_N0.8640.91
455_Q486_P0.8640.91
622_E648_E0.8640.91
529_S533_G0.8610.91
313_D378_R0.8600.91
105_V322_F0.8590.91
518_V600_A0.8590.91
300_D304_D0.8580.91
17_A20_D0.8570.91
333_L384_A0.8570.91
13_I282_V0.8570.91
503_G517_H0.8560.91
87_I106_L0.8540.91
197_D200_V0.8540.91
360_F385_A0.8530.91
322_F382_I0.8520.91
520_I576_I0.8480.91
526_E533_G0.8480.91
225_S228_E0.8460.90
365_Q372_E0.8440.90
588_S593_F0.8430.90
520_I578_L0.8420.90
54_E57_Q0.8410.90
169_L252_L0.8390.90
209_A213_E0.8390.90
498_V604_G0.8390.90
63_I468_I0.8380.90
522_M605_F0.8370.90
508_Q542_G0.8340.90
44_H48_A0.8330.90
324_I334_T0.8320.90
192_N203_E0.8320.90
377_V381_D0.8290.90
259_N262_I0.8280.90
223_I237_Y0.8270.89
193_W196_A0.8230.89
31_L49_T0.8220.89
186_V245_E0.8220.89
71_F81_P0.8220.89
634_D669_Q0.8210.89
470_V474_K0.8190.89
349_V397_L0.8180.89
416_I664_F0.8150.89
357_R400_P0.8140.89
227_A237_Y0.8120.89
41_G45_D0.8100.88
434_A438_L0.8060.88
447_V456_T0.8030.88
365_Q377_V0.8030.88
33_Y272_N0.8010.88
223_I226_A0.7990.88
224_E227_A0.7980.88
507_K511_G0.7980.88
540_I550_I0.7980.88
559_E590_E0.7980.88
110_V278_M0.7970.88
229_A255_R0.7960.88
352_S405_I0.7960.88
227_A231_E0.7960.88
526_E573_D0.7960.88
309_R318_S0.7940.87
388_L397_L0.7900.87
541_K547_G0.7890.87
366_M384_A0.7870.87
315_E340_S0.7870.87
229_A251_A0.7860.87
496_Q524_P0.7840.87
170_Q266_C0.7790.86
252_L261_I0.7780.86
606_K610_P0.7770.86
127_W137_R0.7730.86
227_A233_L0.7720.86
37_N43_V0.7700.86
513_G542_G0.7700.86
556_G560_Q0.7700.86
660_L682_M0.7700.86
152_L211_M0.7690.86
514_Q589_S0.7680.86
489_A687_Y0.7660.86
637_R669_Q0.7650.85
171_L214_L0.7630.85
41_G46_G0.7620.85
551_P555_K0.7620.85
344_N375_K0.7620.85
338_V378_R0.7600.85
112_V142_N0.7600.85
622_E679_S0.7590.85
255_R261_I0.7570.85
511_G514_Q0.7560.85
44_H270_F0.7560.85
33_Y199_G0.7550.85
559_E598_S0.7540.85
439_A447_V0.7530.85
525_L533_G0.7530.85
159_K166_P0.7510.84
89_T99_V0.7500.84
139_A264_V0.7480.84
50_M367_H0.7480.84
110_V282_V0.7470.84
596_A600_A0.7470.84
150_N153_K0.7440.84
522_M574_M0.7430.84
223_I227_A0.7400.84
167_V252_L0.7390.83
317_F342_V0.7390.83
179_F182_V0.7390.83
100_E126_V0.7380.83
139_A154_V0.7350.83
565_P571_V0.7340.83
658_V663_M0.7330.83
293_P296_N0.7320.83
525_L534_Y0.7320.83
167_V225_S0.7320.83
463_E668_T0.7310.83
506_A517_H0.7300.83
107_D136_P0.7300.83
54_E58_E0.7300.83
695_A698_V0.7270.82
15_I110_V0.7260.82
363_I374_I0.7250.82
57_Q369_N0.7230.82
30_I34_T0.7210.82
518_V553_V0.7200.82
538_N545_I0.7200.82
70_A84_I0.7190.82
327_D371_R0.7170.82
153_K156_N0.7170.82
159_K165_N0.7150.81
163_G650_T0.7150.81
567_A699_I0.7130.81
281_A285_Y0.7130.81
518_V578_L0.7130.81
41_G47_A0.7130.81
545_I553_V0.7120.81
432_G456_T0.7090.81
319_A397_L0.7090.81
494_I608_A0.7080.81
73_S280_D0.7070.81
665_G669_Q0.7060.81
301_D304_D0.7050.80
506_A513_G0.7050.80
503_G603_E0.7040.80
224_E237_Y0.7040.80
228_E237_Y0.7010.80
117_G154_V0.7010.80
104_R409_M0.7000.80
657_E688_D0.7000.80
17_A62_T0.6990.80
223_I228_E0.6990.80
594_K598_S0.6990.80
448_W457_I0.6970.80
565_P605_F0.6970.80
25_T40_I0.6970.80
538_N554_D0.6970.80
69_T83_R0.6960.80
16_S409_M0.6960.80
36_V68_T0.6960.80
248_I255_R0.6950.80
542_G580_F0.6940.79
212_V215_A0.6930.79
309_R340_S0.6920.79
515_Y582_S0.6910.79
301_D403_P0.6910.79
232_E247_E0.6900.79
169_L186_V0.6900.79
188_M212_V0.6890.79
591_L594_K0.6890.79
552_A555_K0.6880.79
319_A343_V0.6880.79
508_Q586_V0.6870.79
595_L599_I0.6870.79
41_G48_A0.6870.79
229_A260_E0.6860.79
597_A601_F0.6860.79
345_S373_E0.6850.79
109_A135_V0.6850.79
442_D465_H0.6840.78
510_G513_G0.6820.78
141_V155_V0.6820.78
576_I601_F0.6810.78
600_A604_G0.6810.78
502_E506_A0.6800.78
513_G543_G0.6800.78
581_G587_D0.6800.78
509_S513_G0.6790.78
67_A382_I0.6790.78
493_T613_L0.6770.78
199_G276_Q0.6760.78
557_I601_F0.6750.78
174_G179_F0.6750.78
27_T68_T0.6740.77
378_R381_D0.6740.77
540_I545_I0.6740.77
233_L243_L0.6720.77
85_N381_D0.6720.77
267_G278_M0.6720.77
502_E603_E0.6710.77
628_T632_I0.6710.77
330_V364_V0.6710.77
268_S271_K0.6690.77
555_K558_Q0.6690.77
73_S283_I0.6690.77
227_A230_S0.6690.77
338_V342_V0.6690.77
500_D607_K0.6680.77
298_I303_K0.6680.77
170_Q265_T0.6670.77
619_V682_M0.6670.77
693_N696_Q0.6660.77
494_I604_G0.6660.77
65_S102_S0.6640.76
55_Q59_R0.6640.76
193_W277_A0.6630.76
120_Q622_E0.6630.76
104_R129_Q0.6630.76
553_V556_G0.6630.76
513_G586_V0.6620.76
624_P677_R0.6610.76
227_A234_M0.6610.76
438_L469_I0.6610.76
516_G583_Y0.6600.76
573_D576_I0.6600.76
36_V367_H0.6600.76
493_T573_D0.6590.76
628_T652_V0.6590.76
67_A87_I0.6590.76
116_V153_K0.6580.76
587_D593_F0.6570.76
348_T357_R0.6570.76
117_G146_R0.6570.76
468_I471_D0.6570.76
324_I393_T0.6560.76
567_A612_L0.6560.76
638_R669_Q0.6560.76
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51_D56_E0.6510.75
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469_I473_M0.6490.75
498_V522_M0.6490.75
247_E250_G0.6470.75
223_I233_L0.6470.75
48_A68_T0.6460.74
52_W368_A0.6450.74
513_G584_H0.6450.74
400_P403_P0.6440.74
508_Q543_G0.6440.74
40_I272_N0.6440.74
292_V311_A0.6430.74
667_A680_Y0.6430.74
326_T437_R0.6420.74
10_Y381_D0.6420.74
665_G668_T0.6410.74
114_C143_K0.6400.74
146_R270_F0.6390.74
190_A205_E0.6390.74
151_F266_C0.6390.74
227_A236_K0.6390.74
235_E238_L0.6380.74
605_F610_P0.6380.74
581_G588_S0.6370.73
97_I408_R0.6370.73
552_A556_G0.6360.73
501_V608_A0.6360.73
252_L285_Y0.6350.73
542_G587_D0.6350.73
502_E582_S0.6330.73
293_P311_A0.6320.73
560_Q571_V0.6310.73
145_D268_S0.6310.73
309_R402_A0.6300.73
93_V125_T0.6290.72
28_E48_A0.6290.72
104_R320_L0.6280.72
508_Q584_H0.6280.72
506_A509_S0.6280.72
186_V252_L0.6280.72
460_G466_L0.6270.72
221_N225_S0.6260.72
317_F336_F0.6240.72
542_G584_H0.6240.72
536_F546_P0.6220.72
316_P399_D0.6220.72
549_Y592_A0.6220.72
183_V215_A0.6220.72
230_S248_I0.6220.72
646_E653_K0.6210.72
226_A251_A0.6210.72
193_W276_Q0.6210.72
553_V597_A0.6200.71
170_Q277_A0.6200.71
185_L222_L0.6200.71
241_E251_A0.6200.71
516_G596_A0.6190.71
280_D283_I0.6190.71
222_L227_A0.6190.71
620_E681_T0.6180.71
640_G658_V0.6170.71
170_Q186_V0.6160.71
429_E433_L0.6160.71
236_K243_L0.6160.71
560_Q598_S0.6150.71
108_G287_P0.6150.71
617_M663_M0.6150.71
158_I166_P0.6150.71
584_H588_S0.6140.71
220_Q240_G0.6140.71
486_P664_F0.6140.71
334_T391_V0.6140.71
581_G586_V0.6120.70
534_Y574_M0.6120.70
690_A695_A0.6110.70
539_D575_G0.6100.70
126_V130_A0.6090.70
294_A308_E0.6090.70
351_N358_E0.6080.70
173_I192_N0.6070.70
512_R596_A0.6070.70
114_C120_Q0.6070.70
319_A385_A0.6030.69
541_K544_V0.6030.69
42_E48_A0.6020.69
639_R691_P0.6020.69
495_R610_P0.6010.69
510_G584_H0.6010.69
188_M219_H0.6010.69
438_L477_F0.6010.69
546_P551_P0.6010.69
234_M238_L0.6010.69
536_F540_I0.6000.69
571_V576_I0.5980.69
542_G586_V0.5980.69
99_V126_V0.5970.69
14_G103_M0.5970.69
543_G587_D0.5970.69
367_H372_E0.5970.69
288_S311_A0.5960.68
174_G180_T0.5950.68
44_H50_M0.5950.68
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318_S398_C0.5850.67
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567_A698_V0.5820.67
566_L610_P0.5820.67
94_D99_V0.5820.67
292_V296_N0.5820.67
311_A340_S0.5810.66
103_M109_A0.5800.66
501_V521_D0.5800.66
30_I275_V0.5780.66
229_A232_E0.5780.66
543_G586_V0.5770.66
141_V146_R0.5760.66
506_A515_Y0.5760.66
318_S404_I0.5760.66
174_G181_G0.5740.66
418_I481_A0.5740.66
523_Y537_I0.5740.66
646_E652_V0.5740.66
326_T332_N0.5720.65
171_L182_V0.5720.65
509_S586_V0.5720.65
644_G652_V0.5710.65
514_Q592_A0.5700.65
205_E209_A0.5690.65
119_V162_L0.5680.65
139_A166_P0.5680.65
636_S645_Q0.5680.65
523_Y535_E0.5670.65
584_H593_F0.5670.65
540_I578_L0.5670.65
42_E47_A0.5670.65
555_K594_K0.5660.64
549_Y593_F0.5660.64
522_M597_A0.5660.64
240_G243_L0.5650.64
497_K608_A0.5640.64
185_L218_W0.5630.64
28_E41_G0.5630.64
36_V372_E0.5630.64
503_G512_R0.5630.64
251_A254_Q0.5620.64
100_E133_Y0.5620.64
150_N156_N0.5610.64
32_F37_N0.5610.64
137_R259_N0.5600.64
95_F468_I0.5600.64
516_G519_V0.5600.64
362_R386_I0.5590.63
297_G301_D0.5590.63
406_L463_E0.5570.63
511_G586_V0.5570.63
612_L699_I0.5560.63
512_R544_V0.5550.63
168_P218_W0.5540.63
146_R153_K0.5530.63
358_E389_K0.5530.63
187_K191_I0.5530.63
312_S342_V0.5520.63
556_G597_A0.5510.62
434_A479_V0.5510.62
230_S233_L0.5510.62
96_T129_Q0.5500.62
101_R106_L0.5500.62
565_P604_G0.5500.62
504_K516_G0.5500.62
307_A311_A0.5490.62
560_Q578_L0.5490.62
326_T440_K0.5490.62
398_C404_I0.5480.62
354_K405_I0.5480.62
26_T270_F0.5470.62
298_I304_D0.5470.62
514_Q587_D0.5470.62
242_E245_E0.5460.62
301_D307_A0.5460.62
347_D399_D0.5460.62
540_I553_V0.5460.62
17_A27_T0.5450.62
506_A512_R0.5450.62
44_H60_G0.5450.62
104_R339_Y0.5430.61
525_L537_I0.5430.61
622_E681_T0.5430.61
435_L458_I0.5430.61
385_A388_L0.5420.61
186_V223_I0.5420.61
545_I581_G0.5410.61
266_C465_H0.5410.61
503_G518_V0.5410.61
419_A455_Q0.5410.61
224_E230_S0.5410.61
354_K395_D0.5400.61
140_F265_T0.5400.61
10_Y85_N0.5400.61
99_V104_R0.5400.61
427_D431_M0.5400.61
96_T100_E0.5390.61
122_Q126_V0.5390.61
117_G120_Q0.5380.61
513_G588_S0.5380.61
307_A402_A0.5370.60
474_K481_A0.5370.60
29_R33_Y0.5360.60
588_S592_A0.5360.60
625_E647_S0.5360.60
507_K543_G0.5360.60
339_Y406_L0.5350.60
317_F383_A0.5350.60
551_P554_D0.5350.60
49_T370_K0.5350.60
566_L612_L0.5350.60
16_S130_A0.5340.60
10_Y332_N0.5340.60
503_G582_S0.5340.60
227_A235_E0.5340.60
233_L251_A0.5330.60
510_G586_V0.5330.60
48_A62_T0.5320.60
505_H514_Q0.5320.60
159_K225_S0.5310.60
352_S403_P0.5300.59
396_T406_L0.5300.59
104_R133_Y0.5290.59
493_T574_M0.5280.59
307_A310_H0.5270.59
64_T472_R0.5270.59
180_T205_E0.5270.59
53_M472_R0.5260.59
26_T30_I0.5260.59
170_Q184_D0.5250.59
364_V374_I0.5250.59
639_R687_Y0.5250.59
127_W131_N0.5250.59
248_I252_L0.5240.59
19_I92_H0.5240.59
520_I577_R0.5230.58
696_Q699_I0.5230.58
320_L409_M0.5230.58
689_E695_A0.5220.58
227_A240_G0.5220.58
663_M680_Y0.5220.58
691_P694_V0.5210.58
116_V139_A0.5200.58
350_L357_R0.5200.58
509_S584_H0.5200.58
31_L68_T0.5200.58
418_I458_I0.5200.58
146_R157_Q0.5190.58
364_V371_R0.5190.58
151_F155_V0.5190.58
186_V284_D0.5190.58
269_A275_V0.5190.58
182_V277_A0.5190.58
313_D379_A0.5190.58
170_Q182_V0.5190.58
84_I282_V0.5180.58
171_L222_L0.5180.58
226_A243_L0.5180.58
473_M481_A0.5170.58
60_G99_V0.5160.57
347_D391_V0.5160.57
173_I181_G0.5160.57
666_Y673_L0.5160.57
549_Y587_D0.5150.57
625_E650_T0.5140.57
157_Q160_T0.5140.57
536_F554_D0.5140.57
416_I665_G0.5140.57
365_Q381_D0.5140.57
507_K584_H0.5140.57
219_H222_L0.5140.57
32_F198_Q0.5140.57
557_I560_Q0.5140.57
621_V656_A0.5130.57
512_R598_S0.5130.57
246_A249_K0.5130.57
625_E636_S0.5130.57
58_E471_D0.5130.57
14_G101_R0.5120.57
445_F663_M0.5120.57
391_V395_D0.5120.57
335_F384_A0.5110.57
229_A248_I0.5110.57
364_V675_K0.5110.57
233_L244_T0.5100.57
506_A584_H0.5100.57
522_M601_F0.5100.57
635_L656_A0.5090.56
7_I10_Y0.5090.56
43_V46_G0.5090.56
114_C153_K0.5080.56
627_N630_D0.5080.56
599_I602_K0.5070.56
20_D122_Q0.5070.56
632_I654_I0.5060.56
461_M465_H0.5050.56
297_G404_I0.5050.56
54_E475_R0.5050.56
18_H123_S0.5050.56
611_V695_A0.5050.56
166_P264_V0.5040.56
511_G542_G0.5040.56
34_T86_I0.5040.56
56_E60_G0.5040.56
138_I281_A0.5030.56
52_W66_A0.5030.56
516_G546_P0.5030.56
328_P672_S0.5020.55
224_E234_M0.5010.55
47_A57_Q0.5010.55
12_N15_I0.5010.55
309_R312_S0.5010.55
117_G123_S0.5000.55
527_P572_V0.5000.55
513_G580_F0.5000.55
692_S695_A0.5000.55
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4kiyV 1 0.9787 100 0.208 Contact Map
1darA 1 0.8693 100 0.216 Contact Map
2xexA 1 0.9616 100 0.22 Contact Map
4fn5A 1 0.9432 100 0.239 Contact Map
2dy1A 1 0.9318 100 0.266 Contact Map
4w224 1 0.9787 100 0.272 Contact Map
1n0uA 1 0.9446 100 0.285 Contact Map
3j25A 1 0.8892 100 0.309 Contact Map
2yweA 1 0.652 100 0.51 Contact Map
3cb4D 1 0.6392 100 0.516 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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