GREMLIN Database
DTD - D-aminoacyl-tRNA deacylase
UniProt: P0A6M4 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG11852
Length: 145 (144)
Sequences: 3497 (2390)
Seq/√Len: 199.1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
4_L142_W2.6601.00
10_R132_S2.5891.00
43_N112_R2.5331.00
110_V122_T2.3701.00
15_V20_T2.3051.00
39_E108_Y2.2611.00
42_A108_Y2.2121.00
27_L54_I2.1591.00
112_R115_Q2.1361.00
51_G89_M2.0561.00
103_E107_D2.0321.00
75_V110_V1.9291.00
18_E124_R1.9131.00
65_N68_Q1.9061.00
20_T124_R1.8651.00
10_R134_V1.8281.00
21_G121_Q1.7781.00
38_D41_K1.7561.00
3_A29_V1.7501.00
28_L133_L1.7361.00
101_R104_A1.7151.00
9_T130_Q1.7121.00
8_V28_L1.6931.00
62_M139_V1.6911.00
73_V113_C1.6901.00
34_E82_A1.6831.00
11_A28_L1.6231.00
12_S132_S1.6221.00
75_V109_F1.6011.00
13_V131_V1.5551.00
47_E51_G1.5481.00
46_C113_C1.5151.00
14_T132_S1.4971.00
61_K93_F1.4131.00
57_D63_N1.4091.00
27_L66_V1.3871.00
3_A31_L1.3671.00
14_T19_V1.3651.00
19_V22_E1.3591.00
3_A49_V1.3381.00
43_N108_Y1.3331.00
111_E115_Q1.3291.00
35_K95_K1.3231.00
72_S119_N1.3191.00
30_L133_L1.3101.00
2_I144_Q1.2951.00
130_Q134_V1.2851.00
66_V71_G1.2721.00
130_Q136_D1.2631.00
25_A69_A1.2471.00
2_I142_W1.2451.00
66_V73_V1.2271.00
29_V49_V1.2161.00
111_E114_R1.2131.00
66_V118_M1.2121.00
84_D95_K1.2091.00
35_K98_S1.1981.00
75_V113_C1.1861.00
24_G72_S1.1711.00
41_K44_R1.1681.00
58_A64_L1.1641.00
83_A141_F1.1601.00
56_S93_F1.1581.00
77_S106_Y1.1471.00
85_T143_L1.1421.00
35_K97_A1.1291.00
107_D111_E1.1261.00
9_T134_V1.1241.00
2_I82_A1.1221.00
47_E116_Q1.1211.00
40_Q43_N1.1191.00
108_Y112_R1.1161.00
46_C112_R1.1151.00
75_V106_Y1.1101.00
51_G67_Q1.0991.00
114_R122_T1.0761.00
11_A133_L1.0751.00
12_S22_E1.0741.00
31_L109_F1.0691.00
50_L118_M1.0681.00
56_S60_G1.0641.00
21_G74_L1.0381.00
46_C116_Q1.0331.00
39_E43_N1.0311.00
42_A105_L1.0131.00
49_V109_F1.0111.00
97_A101_R1.0071.00
103_E124_R1.0021.00
34_E95_K0.9881.00
6_Q133_L0.9851.00
72_S121_Q0.9720.99
39_E104_A0.9720.99
9_T136_D0.9710.99
67_Q116_Q0.9580.99
42_A112_R0.9500.99
56_S61_K0.9470.99
36_D101_R0.9300.99
29_V75_V0.9270.99
47_E89_M0.9260.99
100_D103_E0.9100.99
50_L113_C0.9040.99
33_V42_A0.9010.99
98_S101_R0.8960.99
35_K101_R0.8930.99
14_T130_Q0.8810.99
110_V114_R0.8800.99
42_A45_L0.8800.99
64_L67_Q0.8690.99
3_A45_L0.8440.99
101_R105_L0.8420.99
31_L75_V0.8380.98
50_L73_V0.8380.98
32_G82_A0.8370.98
28_L76_V0.8350.98
128_D136_D0.8350.98
64_L68_Q0.8270.98
43_N46_C0.8240.98
34_E144_Q0.8170.98
108_Y111_E0.8160.98
107_D122_T0.8140.98
74_L121_Q0.8130.98
33_V97_A0.8120.98
50_L116_Q0.7990.98
25_A56_S0.7950.98
41_K144_Q0.7940.98
112_R116_Q0.7870.98
43_N47_E0.7840.98
21_G76_V0.7740.97
36_D41_K0.7730.97
33_V45_L0.7720.97
114_R119_N0.7560.97
124_R127_A0.7540.97
45_L109_F0.7440.97
25_A136_D0.7440.97
30_L140_T0.7270.96
78_Q81_L0.7170.96
42_A46_C0.7150.96
131_V135_N0.7130.96
39_E112_R0.7000.95
82_A144_Q0.6830.95
36_D97_A0.6740.94
8_V24_G0.6720.94
53_R63_N0.6700.94
44_R83_A0.6680.94
16_E124_R0.6650.94
15_V124_R0.6600.94
84_D94_S0.6590.94
67_Q70_G0.6550.93
53_R90_R0.6540.93
109_F113_C0.6510.93
13_V20_T0.6470.93
52_Y141_F0.6410.93
5_I49_V0.6380.93
12_S19_V0.6370.92
98_S104_A0.6360.92
41_K45_L0.6280.92
52_Y85_T0.6270.92
55_F71_G0.6270.92
84_D92_S0.6260.92
45_L143_L0.6260.92
7_R139_V0.6250.92
113_C120_T0.6250.92
44_R47_E0.6230.92
29_V73_V0.6150.91
9_T25_A0.6150.91
66_V69_A0.6130.91
16_E19_V0.6120.91
42_A109_F0.6120.91
16_E127_A0.6110.91
4_L30_L0.6100.91
23_I121_Q0.6040.90
103_E126_A0.6030.90
49_V75_V0.6010.90
36_D82_A0.6000.90
46_C50_L0.6000.90
72_S118_M0.5980.90
48_R52_Y0.5820.89
97_A102_A0.5800.89
130_Q133_L0.5730.88
15_V21_G0.5730.88
31_L106_Y0.5720.88
10_R130_Q0.5700.88
82_A96_G0.5690.88
13_V76_V0.5670.87
8_V23_I0.5630.87
141_F144_Q0.5590.87
106_Y109_F0.5570.86
22_E121_Q0.5540.86
7_R136_D0.5530.86
38_D42_A0.5510.86
47_E112_R0.5470.86
102_A125_F0.5450.85
64_L69_A0.5430.85
52_Y143_L0.5430.85
3_A109_F0.5420.85
104_A108_Y0.5380.85
92_S95_K0.5370.84
63_N92_S0.5360.84
5_I143_L0.5340.84
44_R48_R0.5290.84
40_Q44_R0.5280.83
32_G96_G0.5250.83
27_L73_V0.5230.83
32_G142_W0.5220.83
38_D105_L0.5220.83
65_N69_A0.5190.82
63_N90_R0.5180.82
86_E144_Q0.5150.82
99_P126_A0.5110.81
27_L93_F0.5040.81
28_L134_V0.5040.81
93_F99_P0.5020.80
60_G64_L0.5010.80
12_S134_V0.5010.80
15_V127_A0.5000.80
70_G118_M0.5000.80
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1jkeA 5 1 100 0.025 Contact Map
2dboA 2 1 100 0.025 Contact Map
1j7gA 2 0.9931 100 0.032 Contact Map
2okvA 2 0.9931 100 0.045 Contact Map
4nbiA 2 1 100 0.046 Contact Map
1tc5A 2 0.9862 100 0.12 Contact Map
4rriA 2 0.8345 74.4 0.932 Contact Map
4rrfA 2 0.8345 71.5 0.933 Contact Map
4rrqA 2 0.8345 70 0.934 Contact Map
2g5xA 1 0.3586 41.4 0.945 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0064 seconds.