CLSA - ECOLI - GREMLIN Contacts

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CLSA - Cardiolipin synthase A

UniProt:	P0A6H8	Sequences: MTTVYTLVSWLAILGYWLLIAGVTLRILMKRRAVPSAMAWLLIIYILPLVGIIAYLAVGELHLGKRRAERARAMWPSTAKWLNDLKACKHIFAEENSSVAAPLFKLCERRQGIAGVKGNQLQLMTESDDVMQALIRDIQLARHNIEMVFYIWQPGGMADQVAESLMAAARRGIHCRLMLDSAGSVAFFRSPWPELMRNAGIEVVEALKVNLMRVFLRRMDLRQHRKMIMIDNYIAYTGSMNMVDPRYFKQDAGVGQWIDLMARMEGPIATAMGIIYSCDWEIETGKRILPPPPDVNIMPFEQASGHTIHTIASGPGFPEDLIHQALLTAAYSAREYLIMTTPYFVPSDDLLHAICTAAQRGVDVSIILPRKNDSMLVGWASRAFFTELLAAGVKIYQFEGGLLHTKSVLVDGELSLVGTVNLDMRSLWLNFEITLAIDDKGFGADLAAVQDDYISRSRLLDARLWLKRPLWQRVAERLFYFFSPLL	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG11608
Length:	486 (468)
Sequences:	3664 (2738)
Seq/√Len:	126.5

ECOLI - CLSA CLSC CLSB
BACSU - CLS1 CLSA CLSB

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
139_Q	167_A	6.320	1.00
168_A	171_R	6.023	1.00
394_K	459_L	5.890	1.00
137_D	236_Y	5.513	1.00
138_I	164_S	5.400	1.00
363_D	394_K	4.078	1.00
134_L	228_I	3.936	1.00
137_D	263_R	3.752	1.00
235_A	272_M	3.730	1.00
167_A	171_R	3.367	1.00
135_I	164_S	3.297	1.00
152_W	177_L	3.274	1.00
412_G	447_A	3.213	1.00
135_I	161_V	2.974	1.00
122_Q	133_A	2.827	1.00
118_G	267_P	2.773	1.00
120_Q	265_E	2.705	1.00
174_H	202_E	2.687	1.00
130_V	149_F	2.637	1.00
130_V	134_L	2.635	1.00
367_I	457_S	2.617	1.00
400_G	456_R	2.575	1.00
358_A	393_V	2.550	1.00
365_S	394_K	2.530	1.00
310_T	435_L	2.529	1.00
166_M	199_A	2.494	1.00
137_D	140_L	2.484	1.00
452_D	455_S	2.476	1.00
415_S	446_L	2.459	1.00
338_I	365_S	2.407	1.00
458_R	464_L	2.344	1.00
415_S	443_G	2.340	1.00
235_A	269_A	2.338	1.00
416_L	434_T	2.299	1.00
437_I	442_F	2.290	1.00
336_Y	447_A	2.275	1.00
137_D	234_I	2.269	1.00
136_R	140_L	2.256	1.00
162_A	195_L	2.225	1.00
138_I	145_I	2.180	1.00
164_S	168_A	2.153	1.00
236_Y	263_R	2.144	1.00
133_A	236_Y	2.115	1.00
468_R	476_E	2.096	1.00
399_E	458_R	2.093	1.00
336_Y	412_G	2.092	1.00
196_M	201_I	2.080	1.00
146_E	176_R	2.067	1.00
133_A	137_D	2.046	1.00
142_R	233_Y	2.041	1.00
365_S	454_I	2.039	1.00
162_A	166_M	2.031	1.00
329_A	410_V	2.025	1.00
396_Y	459_L	2.022	1.00
367_I	454_I	1.978	1.00
340_T	367_I	1.976	1.00
166_M	170_R	1.964	1.00
370_R	399_E	1.960	1.00
409_L	443_G	1.943	1.00
147_M	228_I	1.938	1.00
462_A	466_L	1.929	1.00
372_N	378_G	1.919	1.00
124_M	133_A	1.919	1.00
142_R	171_R	1.907	1.00
154_P	159_D	1.896	1.00
133_A	263_R	1.894	1.00
330_A	337_L	1.875	1.00
338_I	363_D	1.871	1.00
194_E	198_N	1.861	1.00
227_M	272_M	1.858	1.00
385_F	395_I	1.852	1.00
368_L	385_F	1.848	1.00
139_Q	164_S	1.836	1.00
179_L	205_E	1.810	1.00
447_A	451_D	1.799	1.00
338_I	451_D	1.783	1.00
139_Q	160_Q	1.779	1.00
202_E	286_K	1.778	1.00
382_R	397_Q	1.775	1.00
144_N	273_G	1.763	1.00
337_L	410_V	1.757	1.00
264_M	268_I	1.756	1.00
156_G	250_Q	1.727	1.00
268_I	308_I	1.724	1.00
355_C	387_E	1.708	1.00
126_E	129_D	1.701	1.00
135_I	160_Q	1.692	1.00
258_I	453_Y	1.682	1.00
454_I	457_S	1.674	1.00
204_V	284_T	1.661	1.00
116_V	271_A	1.619	1.00
163_E	166_M	1.617	1.00
144_N	232_N	1.596	1.00
322_I	420_V	1.594	1.00
119_N	264_M	1.578	1.00
162_A	192_W	1.570	1.00
227_M	433_I	1.561	1.00
122_Q	263_R	1.561	1.00
306_H	439_D	1.548	1.00
335_E	412_G	1.545	1.00
132_Q	160_Q	1.535	1.00
233_Y	265_E	1.526	1.00
155_G	158_A	1.526	1.00
126_E	256_Q	1.514	1.00
146_E	273_G	1.511	1.00
336_Y	363_D	1.502	1.00
128_D	132_Q	1.502	1.00
234_I	263_R	1.500	1.00
123_L	449_V	1.492	1.00
147_M	161_V	1.485	1.00
370_R	458_R	1.480	1.00
390_A	462_A	1.473	1.00
329_A	414_L	1.471	1.00
365_S	451_D	1.467	1.00
389_L	462_A	1.465	1.00
388_L	393_V	1.452	1.00
164_S	167_A	1.451	1.00
133_A	136_R	1.444	1.00
308_I	435_L	1.431	1.00
166_M	195_L	1.427	1.00
234_I	265_E	1.427	1.00
125_T	449_V	1.412	1.00
155_G	159_D	1.397	1.00
135_I	139_Q	1.396	1.00
178_M	283_E	1.396	1.00
465_W	468_R	1.391	1.00
47_L	50_V	1.389	1.00
385_F	397_Q	1.387	1.00
121_L	437_I	1.381	1.00
365_S	396_Y	1.380	1.00
340_T	403_L	1.374	1.00
134_L	161_V	1.368	1.00
181_S	205_E	1.353	1.00
122_Q	445_D	1.334	1.00
397_Q	460_L	1.333	1.00
156_G	244_D	1.333	1.00
237_T	272_M	1.326	1.00
338_I	447_A	1.323	1.00
264_M	435_L	1.317	1.00
137_D	230_I	1.311	1.00
157_M	244_D	1.306	1.00
232_N	273_G	1.305	1.00
275_I	312_A	1.305	1.00
175_C	201_I	1.297	1.00
150_Y	430_N	1.297	1.00
246_R	249_K	1.293	1.00
121_L	308_I	1.291	1.00
130_V	261_M	1.284	1.00
132_Q	136_R	1.269	1.00
268_I	310_T	1.266	1.00
384_F	480_Y	1.255	1.00
161_V	242_M	1.246	1.00
139_Q	171_R	1.245	1.00
340_T	407_S	1.227	0.99
243_V	246_R	1.225	0.99
325_A	436_A	1.221	0.99
164_S	171_R	1.202	0.99
115_G	307_T	1.199	0.99
461_D	464_L	1.198	0.99
323_H	347_S	1.196	0.99
136_R	139_Q	1.193	0.99
295_V	298_M	1.191	0.99
107_C	325_A	1.177	0.99
149_F	228_I	1.176	0.99
448_A	452_D	1.172	0.99
159_D	163_E	1.170	0.99
139_Q	168_A	1.169	0.99
382_R	472_Q	1.164	0.99
376_L	479_F	1.164	0.99
275_I	433_I	1.162	0.99
229_M	272_M	1.157	0.99
148_V	223_Q	1.148	0.99
143_H	233_Y	1.137	0.99
344_F	366_I	1.126	0.99
417_V	446_L	1.124	0.99
330_A	357_A	1.119	0.99
262_A	437_I	1.115	0.99
153_Q	246_R	1.112	0.99
162_A	201_I	1.109	0.99
367_I	450_Q	1.107	0.99
383_A	480_Y	1.107	0.99
336_Y	409_L	1.105	0.99
124_M	236_Y	1.105	0.99
340_T	450_Q	1.091	0.99
335_E	413_E	1.087	0.99
337_L	354_I	1.086	0.99
195_L	199_A	1.081	0.99
272_M	433_I	1.066	0.99
379_W	476_E	1.064	0.99
327_L	350_L	1.062	0.99
130_V	240_M	1.059	0.98
223_Q	279_D	1.058	0.98
139_Q	142_R	1.055	0.98
420_V	434_T	1.055	0.98
237_T	433_I	1.050	0.98
152_W	242_M	1.050	0.98
379_W	475_A	1.048	0.98
104_F	107_C	1.047	0.98
123_L	442_F	1.043	0.98
478_L	482_F	1.039	0.98
24_T	45_Y	1.030	0.98
452_D	456_R	1.029	0.98
386_T	466_L	1.025	0.98
389_L	465_W	1.022	0.98
337_L	357_A	1.019	0.98
336_Y	410_V	1.018	0.98
305_G	441_G	1.016	0.98
445_D	448_A	1.015	0.98
161_V	164_S	1.010	0.98
384_F	483_S	1.009	0.98
137_D	265_E	1.006	0.98
415_S	442_F	1.003	0.98
367_I	403_L	1.003	0.98
412_G	444_A	1.001	0.98
160_Q	163_E	0.999	0.98
179_L	192_W	0.998	0.98
294_D	298_M	0.989	0.98
153_Q	243_V	0.987	0.98
163_E	167_A	0.986	0.98
319_E	359_Q	0.985	0.98
310_T	433_I	0.983	0.98
294_D	297_I	0.982	0.98
129_D	132_Q	0.977	0.97
237_T	435_L	0.976	0.97
450_Q	454_I	0.975	0.97
334_R	413_E	0.974	0.97
119_N	267_P	0.974	0.97
350_L	427_L	0.973	0.97
192_W	196_M	0.971	0.97
365_S	459_L	0.969	0.97
169_A	199_A	0.967	0.97
422_L	427_L	0.963	0.97
355_C	359_Q	0.963	0.97
339_M	408_V	0.961	0.97
147_M	242_M	0.951	0.97
331_Y	353_A	0.945	0.97
368_L	381_S	0.942	0.97
169_A	201_I	0.941	0.97
320_D	428_W	0.936	0.97
262_A	435_L	0.932	0.97
451_D	454_I	0.932	0.97
407_S	450_Q	0.930	0.97
220_D	425_R	0.927	0.96
138_I	161_V	0.924	0.96
247_Y	257_W	0.921	0.96
124_M	263_R	0.920	0.96
121_L	306_H	0.919	0.96
39_A	43_I	0.915	0.96
306_H	437_I	0.914	0.96
471_W	475_A	0.912	0.96
256_Q	398_F	0.909	0.96
396_Y	454_I	0.908	0.96
145_I	230_I	0.905	0.96
370_R	397_Q	0.889	0.96
335_E	363_D	0.889	0.96
363_D	459_L	0.889	0.96
140_L	230_I	0.887	0.95
166_M	169_A	0.884	0.95
305_G	439_D	0.882	0.95
370_R	378_G	0.881	0.95
386_T	390_A	0.879	0.95
85_L	88_C	0.879	0.95
388_L	395_I	0.874	0.95
140_L	234_I	0.874	0.95
389_L	460_L	0.870	0.95
125_T	452_D	0.867	0.95
77_S	82_L	0.865	0.95
176_R	202_E	0.862	0.95
371_K	375_M	0.857	0.95
327_L	353_A	0.857	0.95
18_L	22_G	0.856	0.95
149_F	261_M	0.854	0.94
451_D	455_S	0.853	0.94
257_W	401_G	0.850	0.94
122_Q	265_E	0.848	0.94
382_R	385_F	0.847	0.94
382_R	476_E	0.847	0.94
326_L	416_L	0.846	0.94
416_L	436_A	0.843	0.94
182_A	185_V	0.843	0.94
413_E	440_K	0.841	0.94
150_Y	251_D	0.839	0.94
132_Q	135_I	0.839	0.94
389_L	459_L	0.837	0.94
409_L	447_A	0.836	0.94
423_D	430_N	0.836	0.94
146_E	174_H	0.834	0.94
327_L	331_Y	0.833	0.94
229_M	269_A	0.831	0.94
333_A	410_V	0.831	0.94
151_I	246_R	0.830	0.94
193_P	201_I	0.826	0.93
408_V	416_L	0.824	0.93
134_L	230_I	0.822	0.93
344_F	388_L	0.822	0.93
368_L	397_Q	0.820	0.93
386_T	462_A	0.816	0.93
320_D	323_H	0.815	0.93
308_I	437_I	0.815	0.93
315_P	431_F	0.814	0.93
121_L	442_F	0.812	0.93
470_L	473_R	0.811	0.93
155_G	244_D	0.808	0.93
192_W	195_L	0.808	0.93
188_F	192_W	0.808	0.93
358_A	391_A	0.807	0.93
166_M	201_I	0.806	0.93
311_I	325_A	0.803	0.92
228_I	242_M	0.803	0.92
140_L	143_H	0.802	0.92
366_I	395_I	0.801	0.92
104_F	115_G	0.801	0.92
71_A	75_W	0.801	0.92
389_L	395_I	0.800	0.92
260_L	405_T	0.798	0.92
386_T	468_R	0.798	0.92
146_E	232_N	0.797	0.92
323_H	349_D	0.796	0.92
24_T	41_L	0.791	0.92
103_L	106_L	0.790	0.92
131_M	157_M	0.786	0.92
409_L	415_S	0.786	0.92
419_T	433_I	0.785	0.92
309_H	313_S	0.781	0.91
398_F	456_R	0.780	0.91
344_F	351_L	0.779	0.91
459_L	462_A	0.779	0.91
158_A	162_A	0.776	0.91
251_D	255_G	0.768	0.91
116_V	119_N	0.768	0.91
330_A	354_I	0.766	0.91
20_I	24_T	0.765	0.90
474_V	478_L	0.765	0.90
251_D	254_V	0.763	0.90
386_T	465_W	0.763	0.90
398_F	401_G	0.762	0.90
152_W	162_A	0.761	0.90
181_S	207_L	0.761	0.90
42_L	45_Y	0.760	0.90
146_E	277_S	0.760	0.90
63_L	67_R	0.760	0.90
385_F	389_L	0.759	0.90
378_G	397_Q	0.754	0.90
448_A	451_D	0.753	0.90
21_A	25_L	0.753	0.90
472_Q	475_A	0.753	0.90
293_P	296_N	0.750	0.90
442_F	446_L	0.750	0.90
157_M	160_Q	0.747	0.89
344_F	395_I	0.745	0.89
179_L	203_V	0.744	0.89
127_S	131_M	0.742	0.89
131_M	242_M	0.741	0.89
89_K	92_F	0.741	0.89
102_P	334_R	0.738	0.89
264_M	308_I	0.737	0.89
407_S	446_L	0.737	0.89
152_W	161_V	0.735	0.89
260_L	407_S	0.734	0.89
127_S	239_S	0.734	0.89
139_Q	175_C	0.733	0.89
313_S	322_I	0.732	0.88
134_L	137_D	0.732	0.88
237_T	262_A	0.731	0.88
337_L	362_V	0.729	0.88
463_R	467_K	0.727	0.88
146_E	229_M	0.725	0.88
322_I	434_T	0.723	0.88
348_D	352_H	0.721	0.88
99_V	413_E	0.720	0.88
147_M	177_L	0.720	0.88
19_L	26_R	0.718	0.87
450_Q	453_Y	0.717	0.87
409_L	454_I	0.716	0.87
285_G	288_I	0.714	0.87
353_A	357_A	0.714	0.87
167_A	170_R	0.713	0.87
328_T	332_S	0.713	0.87
268_I	271_A	0.713	0.87
77_S	81_W	0.713	0.87
131_M	161_V	0.713	0.87
23_V	56_L	0.712	0.87
408_V	422_L	0.712	0.87
160_Q	164_S	0.711	0.87
324_Q	359_Q	0.709	0.87
90_H	93_A	0.709	0.87
259_D	369_P	0.709	0.87
385_F	460_L	0.708	0.87
16_Y	24_T	0.706	0.87
140_L	233_Y	0.706	0.87
125_T	129_D	0.705	0.87
87_A	90_H	0.705	0.87
243_V	248_F	0.703	0.86
281_E	284_T	0.702	0.86
148_V	242_M	0.701	0.86
193_P	197_R	0.700	0.86
156_G	160_Q	0.699	0.86
306_H	442_F	0.699	0.86
241_N	247_Y	0.698	0.86
157_M	248_F	0.696	0.86
78_T	81_W	0.695	0.86
193_P	203_V	0.694	0.86
249_K	255_G	0.694	0.86
43_I	47_L	0.689	0.85
86_K	90_H	0.688	0.85
357_A	360_R	0.687	0.85
336_Y	365_S	0.687	0.85
101_A	105_K	0.684	0.85
79_A	82_L	0.681	0.85
354_I	393_V	0.681	0.85
188_F	191_P	0.680	0.85
230_I	236_Y	0.679	0.84
351_L	355_C	0.679	0.84
301_E	448_A	0.678	0.84
380_A	479_F	0.676	0.84
265_E	303_A	0.674	0.84
169_A	175_C	0.668	0.83
419_T	430_N	0.666	0.83
166_M	196_M	0.666	0.83
220_D	239_S	0.666	0.83
152_W	192_W	0.665	0.83
159_D	195_L	0.664	0.83
169_A	174_H	0.662	0.83
27_I	37_A	0.661	0.83
42_L	46_I	0.660	0.83
343_Y	373_D	0.660	0.83
277_S	288_I	0.660	0.83
190_S	194_E	0.659	0.83
240_M	261_M	0.656	0.82
188_F	193_P	0.656	0.82
367_I	453_Y	0.655	0.82
344_F	422_L	0.655	0.82
257_W	373_D	0.654	0.82
144_N	277_S	0.654	0.82
458_R	461_D	0.654	0.82
397_Q	458_R	0.653	0.82
324_Q	356_T	0.653	0.82
134_L	419_T	0.652	0.82
442_F	445_D	0.650	0.82
98_S	101_A	0.650	0.82
195_L	198_N	0.648	0.82
355_C	391_A	0.647	0.81
381_S	384_F	0.646	0.81
468_R	473_R	0.646	0.81
187_F	193_P	0.645	0.81
444_A	448_A	0.644	0.81
47_L	54_A	0.644	0.81
66_R	70_R	0.644	0.81
470_L	474_V	0.643	0.81
413_E	439_D	0.642	0.81
440_K	444_A	0.642	0.81
38_M	42_L	0.639	0.81
158_A	242_M	0.637	0.80
88_C	91_I	0.635	0.80
179_L	184_S	0.635	0.80
157_M	242_M	0.633	0.80
135_I	157_M	0.632	0.80
115_G	438_D	0.632	0.80
124_M	130_V	0.632	0.80
246_R	254_V	0.632	0.80
44_I	52_I	0.631	0.80
204_V	283_E	0.630	0.80
449_V	453_Y	0.630	0.80
102_P	360_R	0.628	0.80
154_P	191_P	0.625	0.79
244_D	250_Q	0.624	0.79
73_A	77_S	0.623	0.79
176_R	280_W	0.623	0.79
260_L	453_Y	0.622	0.79
319_E	391_A	0.621	0.79
416_L	420_V	0.618	0.78
16_Y	20_I	0.617	0.78
290_P	293_P	0.616	0.78
68_A	71_A	0.616	0.78
152_W	179_L	0.616	0.78
124_M	129_D	0.614	0.78
20_I	52_I	0.614	0.78
377_V	381_S	0.611	0.78
166_M	173_I	0.611	0.78
244_D	248_F	0.611	0.78
323_H	350_L	0.611	0.78
306_H	440_K	0.611	0.78
221_L	429_L	0.610	0.78
33_A	36_S	0.609	0.77
329_A	336_Y	0.609	0.77
461_D	465_W	0.608	0.77
363_D	451_D	0.607	0.77
239_S	450_Q	0.607	0.77
317_F	321_L	0.606	0.77
221_L	315_P	0.606	0.77
206_A	220_D	0.606	0.77
468_R	472_Q	0.604	0.77
369_P	374_S	0.604	0.77
409_L	412_G	0.603	0.77
15_G	90_H	0.602	0.77
170_R	200_G	0.602	0.77
327_L	330_A	0.602	0.77
326_L	341_T	0.601	0.77
379_W	468_R	0.598	0.76
120_Q	305_G	0.598	0.76
61_L	64_G	0.597	0.76
38_M	41_L	0.597	0.76
243_V	251_D	0.596	0.76
342_P	402_L	0.596	0.76
155_G	241_N	0.596	0.76
124_M	137_D	0.595	0.76
178_M	204_V	0.595	0.76
326_L	420_V	0.595	0.76
128_D	250_Q	0.595	0.76
131_M	135_I	0.595	0.76
177_L	203_V	0.595	0.76
116_V	268_I	0.594	0.76
407_S	417_V	0.593	0.76
119_N	308_I	0.593	0.76
311_I	436_A	0.593	0.76
170_R	198_N	0.591	0.75
246_R	250_Q	0.591	0.75
466_L	469_P	0.590	0.75
469_P	474_V	0.590	0.75
135_I	168_A	0.587	0.75
176_R	276_Y	0.587	0.75
374_S	378_G	0.586	0.75
414_L	436_A	0.586	0.75
380_A	430_N	0.586	0.75
401_G	431_F	0.583	0.74
47_L	80_K	0.583	0.74
53_I	101_A	0.582	0.74
126_E	395_I	0.582	0.74
236_Y	261_M	0.581	0.74
184_S	187_F	0.581	0.74
127_S	157_M	0.581	0.74
462_A	469_P	0.580	0.74
28_L	54_A	0.579	0.74
225_R	279_D	0.576	0.73
281_E	287_R	0.576	0.73
126_E	132_Q	0.576	0.73
369_P	402_L	0.575	0.73
329_A	337_L	0.575	0.73
377_V	380_A	0.573	0.73
89_K	93_A	0.572	0.73
135_I	145_I	0.572	0.73
326_L	434_T	0.571	0.73
130_V	228_I	0.571	0.73
135_I	152_W	0.571	0.73
127_S	259_D	0.570	0.73
156_G	159_D	0.570	0.73
99_V	334_R	0.568	0.72
324_Q	355_C	0.567	0.72
384_F	387_E	0.567	0.72
84_D	98_S	0.567	0.72
197_R	203_V	0.566	0.72
103_L	107_C	0.564	0.72
88_C	92_F	0.564	0.72
60_E	63_L	0.564	0.72
46_I	85_L	0.564	0.72
52_I	56_L	0.563	0.72
279_D	314_G	0.563	0.72
148_V	225_R	0.562	0.72
170_R	199_A	0.562	0.72
20_I	26_R	0.562	0.72
265_E	441_G	0.562	0.72
381_S	385_F	0.561	0.72
154_P	162_A	0.561	0.72
239_S	453_Y	0.560	0.71
443_G	446_L	0.560	0.71
387_E	390_A	0.560	0.71
64_G	68_A	0.559	0.71
91_I	117_K	0.559	0.71
143_H	455_S	0.559	0.71
23_V	52_I	0.558	0.71
78_T	82_L	0.558	0.71
369_P	431_F	0.557	0.71
424_M	428_W	0.556	0.71
48_P	51_G	0.556	0.71
17_W	21_A	0.556	0.71
350_L	422_L	0.555	0.71
409_L	450_Q	0.555	0.71
246_R	374_S	0.554	0.71
349_D	352_H	0.553	0.70
153_Q	242_M	0.552	0.70
96_N	99_V	0.551	0.70
313_S	317_F	0.551	0.70
79_A	83_N	0.550	0.70
117_K	267_P	0.549	0.70
129_D	256_Q	0.548	0.70
338_I	454_I	0.548	0.70
364_V	393_V	0.548	0.70
351_L	387_E	0.546	0.70
347_S	427_L	0.545	0.69
264_M	272_M	0.544	0.69
87_A	95_E	0.544	0.69
338_I	409_L	0.544	0.69
127_S	130_V	0.543	0.69
106_L	110_R	0.543	0.69
78_T	85_L	0.543	0.69
31_R	34_V	0.543	0.69
127_S	261_M	0.542	0.69
369_P	381_S	0.541	0.69
79_A	88_C	0.541	0.69
31_R	477_R	0.540	0.69
454_I	459_L	0.539	0.69
439_D	442_F	0.539	0.69
33_A	38_M	0.539	0.69
375_M	475_A	0.538	0.68
383_A	476_E	0.538	0.68
317_F	322_I	0.537	0.68
92_F	96_N	0.536	0.68
154_P	188_F	0.535	0.68
136_R	142_R	0.535	0.68
16_Y	30_K	0.535	0.68
161_V	470_L	0.534	0.68
126_E	240_M	0.534	0.68
330_A	350_L	0.534	0.68
248_F	402_L	0.534	0.68
158_A	192_W	0.534	0.68
399_E	456_R	0.534	0.68
143_H	174_H	0.532	0.68
368_L	382_R	0.532	0.68
85_L	90_H	0.532	0.68
375_M	379_W	0.532	0.68
298_M	301_E	0.532	0.68
144_N	176_R	0.530	0.67
145_I	165_L	0.530	0.67
138_I	147_M	0.530	0.67
19_L	22_G	0.530	0.67
437_I	443_G	0.530	0.67
26_R	60_E	0.529	0.67
191_P	195_L	0.527	0.67
412_G	443_G	0.527	0.67
130_V	236_Y	0.527	0.67
23_V	26_R	0.527	0.67
268_I	435_L	0.526	0.67
315_P	425_R	0.525	0.67
180_D	225_R	0.525	0.67
29_M	474_V	0.524	0.66
180_D	222_R	0.524	0.66
145_I	175_C	0.524	0.66
23_V	45_Y	0.523	0.66
247_Y	251_D	0.523	0.66
444_A	447_A	0.523	0.66
256_Q	400_G	0.522	0.66
119_N	268_I	0.521	0.66
359_Q	391_A	0.521	0.66
187_F	419_T	0.521	0.66
115_G	309_H	0.520	0.66
276_Y	419_T	0.520	0.66
331_Y	422_L	0.519	0.66
281_E	285_G	0.519	0.66
236_Y	269_A	0.518	0.65
159_D	162_A	0.518	0.65
331_Y	356_T	0.518	0.65
479_F	482_F	0.518	0.65
227_M	310_T	0.516	0.65
356_T	360_R	0.516	0.65
323_H	329_A	0.515	0.65
127_S	220_D	0.515	0.65
131_M	239_S	0.515	0.65
239_S	259_D	0.514	0.65
137_D	233_Y	0.514	0.65
426_S	432_E	0.513	0.65
161_V	228_I	0.513	0.65
379_W	479_F	0.513	0.65
76_P	285_G	0.512	0.65
306_H	441_G	0.512	0.65
19_L	23_V	0.511	0.64
20_I	31_R	0.511	0.64
191_P	194_E	0.511	0.64
60_E	64_G	0.511	0.64
89_K	94_E	0.511	0.64
458_R	469_P	0.511	0.64
370_R	375_M	0.510	0.64
118_G	304_S	0.510	0.64
139_Q	143_H	0.509	0.64
25_L	29_M	0.509	0.64
176_R	273_G	0.509	0.64
99_V	102_P	0.508	0.64
88_C	95_E	0.508	0.64
50_V	54_A	0.508	0.64
41_L	45_Y	0.508	0.64
180_D	342_P	0.507	0.64
164_S	230_I	0.507	0.64
159_D	244_D	0.507	0.64
152_W	158_A	0.507	0.64
191_P	362_V	0.507	0.64
366_I	459_L	0.506	0.64
229_M	277_S	0.506	0.64
37_A	42_L	0.505	0.64
82_L	85_L	0.505	0.64
206_A	431_F	0.505	0.64
234_I	302_Q	0.505	0.64
390_A	466_L	0.505	0.64
128_D	256_Q	0.505	0.64
18_L	21_A	0.503	0.63
145_I	161_V	0.502	0.63
345_V	424_M	0.502	0.63
75_W	90_H	0.502	0.63
84_D	88_C	0.502	0.63
65_K	69_E	0.501	0.63
206_A	239_S	0.501	0.63
62_H	67_R	0.500	0.63
221_L	269_A	0.500	0.63
33_A	41_L	0.500	0.63

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1v0wA	1	0.7798	100	0.494	Contact Map
3hsiA	2	0.784	100	0.502	Contact Map
2o8rA	2	0.7963	100	0.617	Contact Map
1xdpA	4	0.7449	100	0.619	Contact Map
4urjA	1	0.3374	100	0.794	Contact Map
2c1lA	2	0.3683	100	0.806	Contact Map
1byrA	2	0.3086	100	0.809	Contact Map
4gelA	2	0.358	100	0.811	Contact Map
4ggjA	2	0.3374	99.9	0.82	Contact Map
4rctA	2	0.3601	99.4	0.893	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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