HSLU - ECOLI - GREMLIN Contacts

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HSLU - ATP-dependent protease ATPase subunit HslU

UniProt:	P0A6H5	Sequences: MSEMTPREIVSELDKHIIGQDNAKRSVAIALRNRWRRMQLNEELRHEVTPKNILMIGPTGVGKTEIARRLAKLANAPFIKVEATKFTEVGYVGKEVDSIIRDLTDAAVKMVRVQAIEKNRYRAEELAEERILDVLIPPAKNNWGQTEQQQEPSAARQAFRKKLREGQLDDKEIEIDLAAAPMGVEIMAPPGMEEMTSQLQSMFQNLGGQKQKARKLKIKDAMKLLIEEEAAKLVNPEELKQDAIDAVEQHGIVFIDEIDKICKRGESSGPDVSREGVQRDLLPLVEGCTVSTKHGMVKTDHILFIASGAFQIAKPSDLIPELQGRLPIRVELQALTTSDFERILTEPNASITVQYKALMATEGVNIEFTDSGIKRIAEAAWQVNESTENIGARRLHTVLERLMEEISYDASDLSGQNITIDADYVSKHLDALVADEDLSRFIL	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG11881
Length:	443 (436)
Sequences:	1509 (733)
Seq/√Len:	35.1

ECOLI - HSLU
BACSU - CLPY

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
375_R	426_S	6.144	1.00
40_L	48_V	5.586	1.00
216_L	224_L	5.403	1.00
337_T	378_E	4.962	1.00
114_Q	246_A	4.827	1.00
342_R	346_E	4.536	1.00
100_I	253_V	4.531	1.00
131_I	173_I	4.510	1.00
99_I	253_V	4.400	1.00
169_D	222_M	4.293	1.00
128_E	164_R	4.165	1.00
375_R	378_E	4.105	1.00
22_N	333_Q	4.058	1.00
336_T	339_D	4.051	1.00
341_E	374_K	3.974	1.00
161_K	165_E	3.848	1.00
365_N	417_N	3.839	1.00
162_K	167_Q	3.547	1.00
285_V	326_L	3.538	1.00
107_A	247_V	3.407	1.00
115_A	118_K	3.303	1.00
337_T	374_K	3.196	1.00
367_E	417_N	3.176	1.00
115_A	242_D	3.052	1.00
8_E	11_S	3.021	1.00
413_L	416_Q	3.004	1.00
360_A	365_N	2.982	1.00
217_K	220_D	2.927	1.00
117_E	120_R	2.924	1.00
134_V	173_I	2.757	1.00
289_T	296_M	2.753	1.00
357_A	360_A	2.753	1.00
12_E	15_K	2.744	1.00
75_N	114_Q	2.689	1.00
104_T	247_V	2.667	1.00
81_V	255_I	2.665	1.00
14_D	21_D	2.598	1.00
341_E	373_I	2.429	1.00
247_V	302_I	2.400	1.00
423_D	426_S	2.329	0.99
131_I	222_M	2.294	0.99
379_A	398_V	2.294	0.99
245_D	249_Q	2.265	0.99
104_T	244_I	2.200	0.99
247_V	297_V	2.121	0.99
124_E	226_I	2.002	0.98
35_W	39_Q	1.972	0.98
51_K	400_E	1.941	0.98
371_S	422_A	1.905	0.98
104_T	294_H	1.891	0.97
176_D	213_A	1.889	0.97
222_M	226_I	1.888	0.97
113_V	117_E	1.873	0.97
157_Q	165_E	1.871	0.97
386_S	436_E	1.866	0.97
40_L	43_E	1.848	0.97
104_T	297_V	1.847	0.97
366_I	420_I	1.842	0.97
131_I	134_V	1.816	0.97
129_E	160_R	1.813	0.97
246_A	250_H	1.812	0.97
352_T	372_G	1.810	0.97
341_E	370_D	1.807	0.97
367_E	419_T	1.794	0.97
421_D	427_K	1.781	0.96
43_E	348_N	1.779	0.96
185_E	188_A	1.778	0.96
364_V	415_G	1.769	0.96
130_R	228_E	1.749	0.96
25_R	401_R	1.715	0.95
177_L	224_L	1.715	0.95
159_F	162_K	1.702	0.95
7_R	412_D	1.702	0.95
155_A	159_F	1.697	0.95
242_D	245_D	1.687	0.95
11_S	121_Y	1.679	0.95
235_N	238_E	1.676	0.95
155_A	158_A	1.634	0.94
158_A	162_K	1.632	0.94
371_S	421_D	1.604	0.93
115_A	238_E	1.598	0.93
100_I	247_V	1.580	0.93
405_E	409_D	1.574	0.93
46_H	72_K	1.570	0.93
111_V	246_A	1.562	0.93
236_P	239_L	1.562	0.93
108_V	294_H	1.551	0.92
25_R	404_E	1.522	0.92
120_R	124_E	1.511	0.91
79_I	247_V	1.472	0.90
284_L	288_C	1.462	0.90
160_R	164_R	1.458	0.90
116_I	231_A	1.456	0.90
132_L	160_R	1.452	0.89
382_Q	386_S	1.433	0.89
94_K	311_Q	1.430	0.89
383_V	387_T	1.429	0.89
120_R	226_I	1.419	0.88
128_E	160_R	1.415	0.88
353_V	356_K	1.413	0.88
383_V	398_V	1.410	0.88
366_I	403_M	1.407	0.88
352_T	373_I	1.406	0.88
111_V	114_Q	1.391	0.87
133_D	156_R	1.350	0.86
219_K	222_M	1.350	0.86
128_E	163_L	1.343	0.85
16_H	349_A	1.342	0.85
42_E	45_R	1.333	0.85
163_L	168_L	1.330	0.85
79_I	106_A	1.324	0.85
345_T	370_D	1.324	0.85
369_T	419_T	1.322	0.84
131_I	218_I	1.314	0.84
258_I	261_I	1.304	0.84
347_P	442_I	1.302	0.84
35_W	281_L	1.298	0.83
43_E	48_V	1.288	0.83
123_A	127_A	1.287	0.83
263_K	270_P	1.256	0.81
372_G	421_D	1.246	0.81
409_D	416_Q	1.242	0.81
376_I	402_L	1.241	0.80
131_I	221_A	1.234	0.80
184_V	187_M	1.230	0.80
127_A	226_I	1.222	0.79
423_D	427_K	1.219	0.79
163_L	169_D	1.219	0.79
347_P	396_H	1.218	0.79
421_D	424_Y	1.218	0.79
198_Q	201_S	1.215	0.79
163_L	222_M	1.199	0.78
400_E	410_A	1.191	0.78
197_S	200_Q	1.174	0.77
399_L	402_L	1.173	0.77
178_A	228_E	1.169	0.76
226_I	230_A	1.161	0.76
360_A	363_G	1.156	0.76
362_E	415_G	1.155	0.75
105_D	294_H	1.146	0.75
405_E	428_H	1.142	0.75
130_R	229_E	1.138	0.74
422_A	426_S	1.138	0.74
136_I	159_F	1.132	0.74
183_G	187_M	1.129	0.74
369_T	421_D	1.124	0.73
162_K	171_K	1.106	0.72
338_S	374_K	1.098	0.72
336_T	340_F	1.093	0.71
26_S	404_E	1.089	0.71
157_Q	160_R	1.085	0.71
48_V	361_T	1.085	0.71
4_M	11_S	1.083	0.71
109_K	281_L	1.079	0.70
119_N	123_A	1.076	0.70
362_E	412_D	1.074	0.70
356_K	367_E	1.073	0.70
179_A	210_K	1.070	0.70
112_R	236_P	1.069	0.70
187_M	191_G	1.069	0.70
229_E	232_K	1.068	0.69
86_F	99_I	1.067	0.69
159_F	171_K	1.054	0.68
134_V	175_I	1.053	0.68
407_S	410_A	1.052	0.68
192_M	195_M	1.049	0.68
178_A	211_Q	1.045	0.68
110_M	258_I	1.037	0.67
401_R	432_L	1.028	0.67
40_L	366_I	1.026	0.66
44_L	349_A	1.026	0.66
91_Y	272_V	1.020	0.66
379_A	433_V	1.016	0.66
70_L	301_H	1.014	0.65
420_I	424_Y	1.013	0.65
21_D	25_R	1.004	0.65
174_E	213_A	1.002	0.64
264_R	267_S	1.000	0.64
44_L	357_A	0.996	0.64
288_C	396_H	0.995	0.64
25_R	169_D	0.995	0.64
38_M	250_H	0.992	0.64
54_L	84_T	0.992	0.64
170_D	217_K	0.979	0.63
122_R	126_L	0.975	0.62
107_A	244_I	0.974	0.62
91_Y	274_R	0.962	0.61
76_A	79_I	0.958	0.61
40_L	360_A	0.952	0.60
337_T	381_W	0.951	0.60
127_A	222_M	0.951	0.60
43_E	46_H	0.951	0.60
128_E	222_M	0.948	0.60
243_A	301_H	0.941	0.60
176_D	211_Q	0.937	0.59
406_I	418_I	0.937	0.59
104_T	108_V	0.933	0.59
29_I	404_E	0.931	0.59
26_S	328_I	0.927	0.58
262_C	312_I	0.924	0.58
400_E	407_S	0.921	0.58
375_R	422_A	0.918	0.58
379_A	383_V	0.913	0.57
15_K	348_N	0.910	0.57
372_G	406_I	0.910	0.57
291_S	352_T	0.910	0.57
436_E	440_R	0.907	0.57
51_K	410_A	0.904	0.56
18_I	334_A	0.903	0.56
21_D	333_Q	0.897	0.56
111_V	115_A	0.896	0.56
56_I	439_S	0.893	0.56
352_T	366_I	0.891	0.55
110_M	288_C	0.888	0.55
121_Y	124_E	0.885	0.55
111_V	242_D	0.884	0.55
155_A	171_K	0.884	0.55
184_V	188_A	0.883	0.55
108_V	203_F	0.880	0.54
185_E	191_G	0.876	0.54
350_S	353_V	0.876	0.54
350_S	411_S	0.875	0.54
187_M	190_P	0.870	0.54
136_I	155_A	0.869	0.53
85_K	94_K	0.869	0.53
29_I	33_N	0.867	0.53
382_Q	434_A	0.866	0.53
387_T	440_R	0.865	0.53
119_N	230_A	0.863	0.53
174_E	215_K	0.862	0.53
252_I	305_I	0.862	0.53
27_V	66_I	0.861	0.53
239_L	350_S	0.859	0.53
54_L	326_L	0.855	0.52
284_L	326_L	0.855	0.52
297_V	348_N	0.852	0.52
372_G	424_Y	0.852	0.52
136_I	352_T	0.847	0.52
112_R	231_A	0.847	0.52
114_Q	118_K	0.846	0.52
8_E	412_D	0.841	0.51
169_D	219_K	0.841	0.51
125_E	129_E	0.841	0.51
236_P	284_L	0.839	0.51
357_A	405_E	0.836	0.51
409_D	412_D	0.836	0.51
108_V	239_L	0.835	0.51
404_E	424_Y	0.835	0.51
157_Q	161_K	0.833	0.50
406_I	420_I	0.833	0.50
15_K	48_V	0.832	0.50
58_P	84_T	0.830	0.50
162_K	165_E	0.824	0.50
97_D	403_M	0.821	0.49
51_K	407_S	0.817	0.49
374_K	422_A	0.816	0.49
249_Q	340_F	0.816	0.49
56_I	383_V	0.812	0.49
288_C	319_I	0.809	0.48
275_E	350_S	0.806	0.48
86_F	231_A	0.802	0.48
362_E	410_A	0.802	0.48
11_S	16_H	0.797	0.47
262_C	281_L	0.795	0.47
75_N	111_V	0.794	0.47
119_N	127_A	0.793	0.47
382_Q	385_E	0.793	0.47
84_T	138_P	0.792	0.47
218_I	223_K	0.790	0.47
362_E	413_L	0.789	0.47
91_Y	320_P	0.789	0.47
379_A	430_D	0.784	0.46
334_A	389_N	0.780	0.46
127_A	230_A	0.779	0.46
172_E	215_K	0.778	0.46
26_S	203_F	0.777	0.46
92_V	272_V	0.774	0.45
86_F	136_I	0.774	0.45
253_V	284_L	0.773	0.45
201_S	207_G	0.768	0.45
359_M	403_M	0.768	0.45
439_S	442_I	0.766	0.45
185_E	194_E	0.764	0.44
347_P	439_S	0.763	0.44
193_E	196_T	0.753	0.44
118_K	122_R	0.753	0.44
307_S	373_I	0.752	0.43
185_E	189_P	0.750	0.43
188_A	196_T	0.747	0.43
274_R	320_P	0.745	0.43
356_K	359_M	0.744	0.43
378_E	382_Q	0.744	0.43
315_P	329_R	0.744	0.43
130_R	135_L	0.742	0.43
7_R	43_E	0.742	0.43
126_L	232_K	0.740	0.42
108_V	240_K	0.739	0.42
166_G	169_D	0.738	0.42
409_D	413_L	0.738	0.42
18_I	21_D	0.737	0.42
132_L	159_F	0.737	0.42
100_I	121_Y	0.734	0.42
379_A	402_L	0.733	0.42
97_D	215_K	0.733	0.42
204_Q	337_T	0.729	0.42
190_P	281_L	0.728	0.41
17_I	27_V	0.728	0.41
193_E	200_Q	0.727	0.41
150_Q	154_A	0.725	0.41
334_A	342_R	0.723	0.41
190_P	198_Q	0.723	0.41
126_L	215_K	0.722	0.41
173_I	225_L	0.722	0.41
123_A	233_L	0.722	0.41
328_I	439_S	0.721	0.41
29_I	372_G	0.721	0.41
132_L	163_L	0.720	0.41
8_E	117_E	0.719	0.41
92_V	274_R	0.719	0.41
284_L	307_S	0.718	0.41
31_L	74_A	0.716	0.40
212_K	237_E	0.716	0.40
112_R	234_V	0.713	0.40
401_R	404_E	0.711	0.40
158_A	171_K	0.711	0.40
356_K	360_A	0.711	0.40
75_N	246_A	0.710	0.40
190_P	297_V	0.710	0.40
179_A	211_Q	0.710	0.40
9_I	61_V	0.709	0.40
359_M	415_G	0.708	0.40
29_I	318_L	0.707	0.40
38_M	255_I	0.706	0.40
7_R	409_D	0.706	0.40
79_I	253_V	0.705	0.40
194_E	261_I	0.705	0.40
132_L	136_I	0.704	0.39
356_K	374_K	0.703	0.39
240_K	294_H	0.703	0.39
136_I	441_F	0.702	0.39
312_I	385_E	0.700	0.39
175_I	216_L	0.699	0.39
356_K	365_N	0.698	0.39
347_P	398_V	0.698	0.39
167_Q	372_G	0.697	0.39
18_I	182_M	0.696	0.39
187_M	192_M	0.694	0.39
290_V	420_I	0.694	0.39
188_A	194_E	0.692	0.38
104_T	118_K	0.692	0.38
95_E	311_Q	0.690	0.38
127_A	218_I	0.682	0.38
26_S	131_I	0.680	0.38
173_I	217_K	0.680	0.38
54_L	175_I	0.679	0.37
157_Q	337_T	0.678	0.37
202_M	369_T	0.678	0.37
154_A	158_A	0.676	0.37
265_G	270_P	0.675	0.37
161_K	167_Q	0.675	0.37
9_I	433_V	0.675	0.37
237_E	360_A	0.674	0.37
177_L	363_G	0.672	0.37
341_E	356_K	0.671	0.37
51_K	424_Y	0.671	0.37
227_E	250_H	0.670	0.37
47_E	361_T	0.670	0.37
39_Q	281_L	0.669	0.37
54_L	230_A	0.668	0.37
198_Q	207_G	0.667	0.36
91_Y	156_R	0.667	0.36
18_I	382_Q	0.666	0.36
426_S	430_D	0.661	0.36
11_S	14_D	0.660	0.36
94_K	101_R	0.659	0.36
99_I	284_L	0.656	0.36
217_K	222_M	0.656	0.36
188_A	275_E	0.655	0.36
84_T	307_S	0.655	0.36
429_L	433_V	0.654	0.35
129_E	265_G	0.653	0.35
202_M	360_A	0.653	0.35
111_V	429_L	0.652	0.35
236_P	240_K	0.652	0.35
173_I	218_I	0.649	0.35
380_A	398_V	0.648	0.35
97_D	428_H	0.648	0.35
347_P	399_L	0.647	0.35
356_K	441_F	0.647	0.35
424_Y	428_H	0.645	0.35
47_E	73_L	0.645	0.35
366_I	406_I	0.644	0.35
186_I	193_E	0.644	0.35
15_K	313_A	0.644	0.35
211_Q	297_V	0.643	0.35
125_E	405_E	0.643	0.35
127_A	229_E	0.642	0.35
265_G	297_V	0.642	0.35
188_A	193_E	0.642	0.35
110_M	347_P	0.641	0.34
200_Q	429_L	0.641	0.34
338_S	341_E	0.640	0.34
151_E	430_D	0.640	0.34
221_A	224_L	0.635	0.34
350_S	355_Y	0.634	0.34
97_D	355_Y	0.634	0.34
76_A	200_Q	0.634	0.34
352_T	399_L	0.633	0.34
231_A	234_V	0.633	0.34
359_M	371_S	0.633	0.34
351_I	399_L	0.632	0.34
275_E	412_D	0.632	0.34
56_I	432_L	0.630	0.34
255_I	431_A	0.628	0.33
176_D	378_E	0.627	0.33
362_E	372_G	0.626	0.33
371_S	406_I	0.625	0.33
265_G	441_F	0.624	0.33
328_I	331_E	0.624	0.33
125_E	161_K	0.623	0.33
131_I	169_D	0.623	0.33
376_I	399_L	0.622	0.33
16_H	350_S	0.622	0.33
223_K	238_E	0.622	0.33
432_L	439_S	0.621	0.33
3_E	39_Q	0.621	0.33
248_E	340_F	0.620	0.33
100_I	104_T	0.620	0.33
133_D	138_P	0.620	0.33
8_E	164_R	0.619	0.33
371_S	423_D	0.618	0.33
56_I	315_P	0.617	0.33
412_D	416_Q	0.615	0.32
40_L	271_D	0.615	0.32
342_R	347_P	0.614	0.32
383_V	432_L	0.613	0.32
15_K	18_I	0.611	0.32
7_R	426_S	0.611	0.32
4_M	8_E	0.611	0.32
347_P	412_D	0.610	0.32
124_E	128_E	0.610	0.32
326_L	334_A	0.609	0.32
406_I	416_Q	0.609	0.32
364_V	414_S	0.608	0.32
29_I	212_K	0.608	0.32
352_T	428_H	0.608	0.32
174_E	289_T	0.607	0.32
47_E	99_I	0.607	0.32
35_W	74_A	0.606	0.32
129_E	408_Y	0.606	0.32
379_A	429_L	0.605	0.32
390_I	397_T	0.605	0.32
162_K	262_C	0.605	0.32
95_E	101_R	0.605	0.32
244_I	328_I	0.604	0.32
374_K	421_D	0.604	0.32
15_K	297_V	0.604	0.32
171_K	341_E	0.603	0.32
94_K	108_V	0.602	0.31
100_I	396_H	0.601	0.31
76_A	84_T	0.599	0.31
267_S	270_P	0.599	0.31
15_K	174_E	0.599	0.31
72_K	441_F	0.598	0.31
100_I	302_I	0.597	0.31
130_R	232_K	0.597	0.31
38_M	48_V	0.596	0.31
337_T	375_R	0.596	0.31
5_T	137_P	0.596	0.31
271_D	307_S	0.596	0.31
122_R	125_E	0.595	0.31
429_L	432_L	0.595	0.31
111_V	250_H	0.594	0.31
151_E	154_A	0.593	0.31
128_E	157_Q	0.592	0.31
182_M	217_K	0.591	0.31
46_H	298_K	0.591	0.31
48_V	212_K	0.591	0.31
49_T	244_I	0.590	0.31
134_V	307_S	0.589	0.31
25_R	127_A	0.589	0.31
109_K	296_M	0.588	0.30
107_A	110_M	0.588	0.30
107_A	161_K	0.587	0.30
341_E	345_T	0.586	0.30
17_I	255_I	0.585	0.30
26_S	220_D	0.585	0.30
362_E	416_Q	0.583	0.30
386_S	433_V	0.583	0.30
137_P	319_I	0.582	0.30
12_E	229_E	0.581	0.30
75_N	184_V	0.579	0.30
234_V	288_C	0.579	0.30
411_S	424_Y	0.578	0.30
211_Q	396_H	0.576	0.30
386_S	440_R	0.575	0.30
359_M	416_Q	0.573	0.29
44_L	135_L	0.573	0.29
177_L	423_D	0.573	0.29
54_L	315_P	0.573	0.29
55_M	66_I	0.572	0.29
383_V	439_S	0.572	0.29
186_I	199_L	0.568	0.29
195_M	261_I	0.567	0.29
255_I	306_A	0.567	0.29
132_L	155_A	0.566	0.29
179_A	202_M	0.565	0.29
58_P	389_N	0.565	0.29
396_H	399_L	0.564	0.29
213_A	293_K	0.563	0.29
238_E	398_V	0.563	0.29
415_G	421_D	0.563	0.29
40_L	399_L	0.563	0.29
187_M	195_M	0.562	0.29
364_V	413_L	0.560	0.28
21_D	369_T	0.560	0.28
138_P	398_V	0.559	0.28
185_E	192_M	0.559	0.28
181_P	220_D	0.559	0.28
274_R	293_K	0.559	0.28
369_T	418_I	0.558	0.28
21_D	427_K	0.558	0.28
84_T	400_E	0.557	0.28
132_L	156_R	0.557	0.28
155_A	162_K	0.556	0.28
240_K	244_I	0.556	0.28
107_A	246_A	0.555	0.28
252_I	376_I	0.555	0.28
15_K	229_E	0.555	0.28
301_H	415_G	0.554	0.28
133_D	155_A	0.554	0.28
92_V	320_P	0.554	0.28
137_P	140_K	0.553	0.28
3_E	38_M	0.552	0.28
189_P	195_M	0.551	0.28
149_Q	152_P	0.551	0.28
27_V	123_A	0.550	0.28
110_M	368_F	0.549	0.28
419_T	432_L	0.548	0.28
106_A	302_I	0.548	0.28
124_E	222_M	0.547	0.28
38_M	348_N	0.546	0.27
28_A	423_D	0.546	0.27
334_A	436_E	0.546	0.27
334_A	337_T	0.545	0.27
16_H	438_L	0.545	0.27
154_A	367_E	0.545	0.27
179_A	352_T	0.544	0.27
48_V	366_I	0.544	0.27
110_M	247_V	0.543	0.27
16_H	233_L	0.542	0.27
174_E	232_K	0.542	0.27
244_I	298_K	0.542	0.27
280_D	283_P	0.542	0.27
25_R	409_D	0.542	0.27
21_D	225_L	0.541	0.27
150_Q	227_E	0.540	0.27
111_V	285_V	0.540	0.27
61_V	355_Y	0.540	0.27
92_V	388_E	0.539	0.27
340_F	381_W	0.538	0.27
38_M	288_C	0.538	0.27
194_E	198_Q	0.537	0.27
35_W	159_F	0.537	0.27
106_A	158_A	0.537	0.27
313_A	417_N	0.537	0.27
402_L	427_K	0.537	0.27
234_V	434_A	0.537	0.27
328_I	377_A	0.537	0.27
348_N	353_V	0.535	0.27
155_A	281_L	0.535	0.27
11_S	107_A	0.535	0.27
202_M	205_N	0.535	0.27
58_P	152_P	0.534	0.27
29_I	442_I	0.533	0.27
197_S	204_Q	0.533	0.27
35_W	38_M	0.530	0.26
191_G	195_M	0.530	0.26
111_V	261_I	0.530	0.26
84_T	326_L	0.530	0.26
337_T	418_I	0.529	0.26
230_A	244_I	0.529	0.26
235_N	326_L	0.529	0.26
297_V	302_I	0.529	0.26
135_L	218_I	0.528	0.26
197_S	201_S	0.528	0.26
92_V	355_Y	0.528	0.26
184_V	373_I	0.528	0.26
374_K	378_E	0.527	0.26
132_L	157_Q	0.527	0.26
134_V	218_I	0.527	0.26
232_K	314_K	0.527	0.26
289_T	300_D	0.527	0.26
167_Q	173_I	0.527	0.26
79_I	288_C	0.527	0.26
128_E	132_L	0.526	0.26
54_L	284_L	0.526	0.26
27_V	70_L	0.526	0.26
119_N	234_V	0.525	0.26
281_L	284_L	0.525	0.26
242_D	386_S	0.524	0.26
51_K	84_T	0.524	0.26
196_T	349_A	0.524	0.26
86_F	97_D	0.524	0.26
316_S	346_E	0.524	0.26
91_Y	201_S	0.524	0.26
75_N	250_H	0.524	0.26
11_S	124_E	0.523	0.26
269_G	272_V	0.523	0.26
193_E	319_I	0.523	0.26
289_T	298_K	0.521	0.26
22_N	418_I	0.521	0.26
118_K	223_K	0.520	0.26
98_S	158_A	0.520	0.26
161_K	170_D	0.520	0.26
212_K	272_V	0.518	0.26
385_E	388_E	0.516	0.25
237_E	420_I	0.514	0.25
376_I	398_V	0.514	0.25
206_L	214_R	0.514	0.25
9_I	225_L	0.513	0.25
126_L	129_E	0.513	0.25
174_E	269_G	0.513	0.25
364_V	416_Q	0.512	0.25
137_P	285_V	0.512	0.25
17_I	47_E	0.510	0.25
136_I	158_A	0.510	0.25
49_T	240_K	0.509	0.25
91_Y	123_A	0.509	0.25
336_T	430_D	0.509	0.25
5_T	381_W	0.509	0.25
67_A	222_M	0.509	0.25
49_T	199_L	0.508	0.25
337_T	341_E	0.508	0.25
288_C	398_V	0.507	0.25
41_N	360_A	0.507	0.25
409_D	428_H	0.506	0.25
181_P	232_K	0.506	0.25
178_A	208_G	0.506	0.25
108_V	363_G	0.506	0.25
45_R	249_Q	0.506	0.25
138_P	255_I	0.504	0.25
121_Y	178_A	0.504	0.25
106_A	401_R	0.504	0.25
40_L	400_E	0.504	0.25
285_V	334_A	0.503	0.25
123_A	272_V	0.502	0.25
336_T	364_V	0.502	0.25
245_D	421_D	0.501	0.25
56_I	307_S	0.501	0.25
375_R	433_V	0.501	0.25
261_I	326_L	0.501	0.25
174_E	359_M	0.500	0.24
263_K	271_D	0.500	0.24

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1g41A	3	0.754	100	0.616	Contact Map
1ofhA	3	0.6975	100	0.742	Contact Map
1um8A	1	0.614	100	0.811	Contact Map
1r6bX	1	0.6321	100	0.827	Contact Map
3hwsA	3	0.6637	100	0.829	Contact Map
3pxiA	3	0.5688	100	0.84	Contact Map
1qvrA	3	0.5801	100	0.85	Contact Map
4d2uA	3	0.8962	100	0.852	Contact Map
4ciuA	1	0.5959	100	0.858	Contact Map
4lj9A	1	0.6163	99.9	0.872	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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