CH60 - ECOLI - GREMLIN Contacts

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CH60 - 60 kDa chaperonin

UniProt:	P0A6F5	Sequences: MAAKDVKFGNDARVKMLRGVNVLADAVKVTLGPKGRNVVLDKSFGAPTITKDGVSVAREIELEDKFENMGAQMVKEVASKANDAAGDGTTTATVLAQAIITEGLKAVAAGMNPMDLKRGIDKAVTAAVEELKALSVPCSDSKAIAQVGTISANSDETVGKLIAEAMDKVGKEGVITVEDGTGLQDELDVVEGMQFDRGYLSPYFINKPETGAVELESPFILLADKKISNIREMLPVLEAVAKAGKPLLIIAEDVEGEALATLVVNTMRGIVKVAAVKAPGFGDRRKAMLQDIATLTGGTVISEEIGMELEKATLEDLGQAKRVVINKDTTTIIDGVGEEAAIQGRVAQIRQQIEEATSDYDREKLQERVAKLAGGVAVIKVGAATEVEMKEKKARVEDALHATRAAVEEGVVAGGGVALIRVASKLADLRGQNEDQNVGIKVALRAMEAPLRQIVLNCGEEPSVVANTVKGGDGNYGYNAATEEYGNMIDMGILDPTKVTRSALQYAASVAGLMITTECMVTDLPKNDAADLGAAGGMGGMGGMGGMM	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10599
Length:	548 (533)
Sequences:	2882 (1077)
Seq/√Len:	46.7

ECOLI - CH60
BACSU - CH60
HALSA - THSA THSB
SULSO - THSB THSG

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
135_S	497_T	5.641	1.00
274_A	325_I	5.047	1.00
479_N	482_T	4.953	1.00
131_L	497_T	4.480	1.00
130_E	133_A	4.116	1.00
486_G	491_M	4.031	1.00
465_V	485_Y	3.956	1.00
460_E	478_Y	3.871	1.00
479_N	486_G	3.813	1.00
478_Y	483_E	3.790	1.00
487_N	490_D	3.622	1.00
451_L	469_V	3.559	1.00
468_T	471_G	3.415	1.00
338_E	341_A	3.384	1.00
120_I	508_A	3.312	1.00
121_D	512_G	3.145	1.00
21_N	25_D	3.096	1.00
51_K	56_V	3.087	1.00
124_V	508_A	2.886	1.00
287_A	290_Q	2.856	1.00
427_A	444_L	2.826	1.00
122_K	436_Q	2.766	1.00
18_R	67_E	2.735	1.00
426_L	440_I	2.734	1.00
339_E	343_Q	2.722	1.00
18_R	22_V	2.695	1.00
166_M	407_V	2.674	1.00
486_G	493_I	2.651	1.00
17_L	21_N	2.636	1.00
217_S	245_K	2.567	1.00
21_N	97_Q	2.519	1.00
326_N	329_T	2.515	1.00
145_A	160_K	2.493	1.00
460_E	483_E	2.491	1.00
250_I	292_I	2.467	1.00
213_V	274_A	2.435	1.00
115_D	436_Q	2.429	1.00
28_K	97_Q	2.416	1.00
131_L	418_A	2.409	1.00
222_L	298_G	2.399	1.00
215_L	248_L	2.378	1.00
15_K	18_R	2.357	1.00
127_A	447_M	2.354	1.00
475_N	487_N	2.349	1.00
394_A	397_E	2.309	1.00
419_L	500_T	2.308	1.00
99_I	120_I	2.305	1.00
156_E	160_K	2.277	1.00
10_N	14_V	2.225	1.00
100_I	514_M	2.222	1.00
359_D	362_R	2.190	1.00
46_A	387_V	2.176	1.00
102_E	445_R	2.149	1.00
72_Q	75_K	2.144	1.00
143_A	146_Q	2.135	1.00
6_V	519_C	2.130	1.00
299_T	316_D	2.119	1.00
488_M	493_I	2.110	1.00
448_E	470_K	2.091	1.00
431_G	440_I	2.078	1.00
532_L	535_A	2.064	1.00
479_N	493_I	2.053	1.00
420_I	451_L	2.049	1.00
313_T	316_D	2.045	0.99
117_K	121_D	2.044	0.99
455_V	462_P	2.038	0.99
40_L	521_V	2.002	0.99
141_S	167_D	1.995	0.99
321_K	334_D	1.972	0.99
125_T	129_E	1.964	0.99
411_V	494_L	1.953	0.99
106_A	438_V	1.949	0.99
126_A	129_E	1.944	0.99
301_I	312_A	1.933	0.99
320_A	332_I	1.932	0.99
222_L	292_I	1.915	0.99
455_V	460_E	1.905	0.99
356_A	362_R	1.872	0.99
48_T	394_A	1.859	0.99
472_G	476_Y	1.855	0.99
120_I	443_A	1.841	0.99
420_I	470_K	1.840	0.99
140_D	143_A	1.835	0.99
529_A	532_L	1.833	0.99
186_E	380_K	1.825	0.99
99_I	443_A	1.819	0.99
51_K	153_N	1.810	0.99
136_V	143_A	1.784	0.99
239_A	313_T	1.783	0.99
20_V	514_M	1.778	0.99
417_V	421_R	1.778	0.99
25_D	97_Q	1.775	0.99
349_I	369_V	1.773	0.99
160_K	164_E	1.773	0.99
101_T	449_A	1.762	0.98
245_K	319_Q	1.740	0.98
5_D	524_L	1.739	0.98
106_A	111_M	1.738	0.98
353_I	369_V	1.734	0.98
82_N	401_H	1.728	0.98
82_N	394_A	1.723	0.98
129_E	133_A	1.709	0.98
139_S	143_A	1.700	0.98
130_E	134_L	1.678	0.98
530_A	533_G	1.661	0.98
195_F	276_V	1.645	0.98
123_A	443_A	1.625	0.97
467_N	471_G	1.621	0.97
228_S	255_E	1.612	0.97
127_A	422_V	1.611	0.97
421_R	475_N	1.609	0.97
421_R	474_G	1.604	0.97
239_A	242_K	1.579	0.97
319_Q	336_V	1.567	0.97
448_E	452_R	1.563	0.97
219_F	319_Q	1.563	0.97
431_G	437_N	1.552	0.97
220_I	320_A	1.552	0.97
437_N	441_K	1.551	0.97
531_D	534_A	1.536	0.96
63_E	527_N	1.526	0.96
69_M	522_T	1.520	0.96
5_D	522_T	1.519	0.96
130_E	425_K	1.519	0.96
429_L	440_I	1.514	0.96
451_L	455_V	1.508	0.96
441_K	444_L	1.499	0.96
69_M	520_M	1.496	0.96
383_A	389_M	1.486	0.96
5_D	523_D	1.459	0.95
21_N	101_T	1.444	0.95
400_L	404_R	1.442	0.95
141_S	164_E	1.442	0.95
346_V	373_A	1.440	0.95
454_I	480_A	1.438	0.95
426_L	444_L	1.436	0.95
222_L	250_I	1.432	0.95
394_A	401_H	1.429	0.94
479_N	491_M	1.428	0.94
111_M	438_V	1.428	0.94
43_S	65_K	1.409	0.94
350_R	373_A	1.401	0.94
188_D	380_K	1.401	0.94
7_K	66_F	1.400	0.94
111_M	435_D	1.399	0.94
66_F	522_T	1.390	0.94
115_D	481_A	1.386	0.94
216_E	322_R	1.369	0.93
82_N	397_E	1.364	0.93
15_K	64_D	1.359	0.93
217_S	319_Q	1.351	0.93
408_E	498_K	1.348	0.93
136_V	489_I	1.342	0.92
248_L	325_I	1.333	0.92
127_A	426_L	1.331	0.92
353_I	359_D	1.331	0.92
340_A	343_Q	1.323	0.92
341_A	344_G	1.321	0.92
425_K	428_D	1.320	0.92
323_V	332_I	1.319	0.92
115_D	118_R	1.316	0.92
420_I	423_A	1.311	0.91
132_K	501_R	1.306	0.91
343_Q	347_A	1.306	0.91
17_L	104_L	1.300	0.91
199_Y	211_G	1.296	0.91
42_K	59_E	1.288	0.91
423_A	447_M	1.282	0.91
63_E	524_L	1.277	0.90
307_M	316_D	1.265	0.90
501_R	505_Q	1.265	0.90
126_A	429_L	1.264	0.90
445_R	449_A	1.262	0.90
115_D	433_N	1.258	0.90
218_P	320_A	1.258	0.90
66_F	520_M	1.256	0.90
363_E	366_Q	1.256	0.90
51_K	394_A	1.254	0.90
128_V	132_K	1.245	0.89
121_D	125_T	1.240	0.89
391_E	395_R	1.234	0.89
308_E	311_K	1.231	0.89
225_K	303_E	1.228	0.89
222_L	300_V	1.227	0.88
460_E	465_V	1.224	0.88
129_E	132_K	1.213	0.88
207_K	210_T	1.212	0.88
200_L	254_V	1.211	0.88
421_R	469_V	1.205	0.88
430_R	437_N	1.205	0.88
340_A	344_G	1.205	0.88
260_A	264_V	1.204	0.88
364_K	367_E	1.195	0.87
266_T	272_K	1.194	0.87
142_K	490_D	1.193	0.87
128_V	505_Q	1.188	0.87
266_T	269_G	1.184	0.87
301_I	316_D	1.179	0.86
434_E	437_N	1.175	0.86
292_I	332_I	1.173	0.86
207_K	214_E	1.170	0.86
165_A	187_L	1.169	0.86
134_L	137_P	1.161	0.86
172_E	350_R	1.155	0.85
214_E	322_R	1.151	0.85
533_G	536_G	1.151	0.85
514_M	520_M	1.147	0.85
468_T	472_G	1.136	0.84
424_S	427_A	1.129	0.84
524_L	529_A	1.121	0.83
312_A	316_D	1.120	0.83
215_L	274_A	1.120	0.83
149_T	156_E	1.117	0.83
168_K	191_E	1.116	0.83
126_A	425_K	1.114	0.83
229_N	232_E	1.108	0.83
523_D	526_K	1.107	0.83
17_L	101_T	1.103	0.82
81_A	506_Y	1.102	0.82
409_E	501_R	1.101	0.82
252_E	285_R	1.095	0.82
224_D	312_A	1.091	0.82
131_L	422_V	1.073	0.81
527_N	530_A	1.072	0.81
141_S	160_K	1.072	0.81
484_E	491_M	1.066	0.80
249_I	273_V	1.065	0.80
166_M	175_I	1.064	0.80
423_A	470_K	1.059	0.80
430_R	440_I	1.058	0.80
467_N	470_K	1.053	0.79
180_G	389_M	1.053	0.79
337_G	342_I	1.052	0.79
56_V	394_A	1.051	0.79
469_V	485_Y	1.041	0.79
50_T	391_E	1.034	0.78
219_F	245_K	1.029	0.78
230_I	261_T	1.028	0.78
126_A	428_D	1.027	0.78
435_D	438_V	1.026	0.78
290_Q	341_A	1.026	0.78
218_P	323_V	1.025	0.78
22_V	67_E	1.022	0.77
347_A	351_Q	1.017	0.77
302_S	305_I	1.016	0.77
248_L	274_A	1.016	0.77
301_I	307_M	1.011	0.77
7_K	15_K	1.005	0.76
433_N	440_I	1.003	0.76
28_K	453_Q	1.000	0.76
352_Q	355_E	0.996	0.75
50_T	394_A	0.987	0.75
525_P	529_A	0.986	0.75
193_M	295_L	0.986	0.75
145_A	148_G	0.983	0.75
213_V	325_I	0.980	0.74
280_G	288_M	0.979	0.74
307_M	312_A	0.978	0.74
346_V	350_R	0.971	0.74
11_D	15_K	0.967	0.73
23_L	74_V	0.962	0.73
320_A	323_V	0.958	0.73
469_V	476_Y	0.956	0.72
225_K	298_G	0.955	0.72
290_Q	305_I	0.954	0.72
219_F	243_A	0.952	0.72
118_R	121_D	0.945	0.72
147_V	411_V	0.944	0.71
78_A	93_T	0.939	0.71
433_N	436_Q	0.938	0.71
468_T	476_Y	0.937	0.71
161_L	187_L	0.937	0.71
437_N	440_I	0.936	0.71
253_D	277_K	0.930	0.70
284_R	361_D	0.929	0.70
290_Q	294_T	0.928	0.70
532_L	536_G	0.917	0.69
290_Q	352_Q	0.912	0.69
120_I	439_G	0.910	0.69
24_A	97_Q	0.908	0.68
244_G	272_K	0.907	0.68
126_A	133_A	0.905	0.68
153_N	394_A	0.903	0.68
220_I	248_L	0.900	0.68
223_A	227_I	0.898	0.68
476_Y	486_G	0.896	0.67
451_L	466_A	0.893	0.67
15_K	67_E	0.893	0.67
111_M	434_E	0.890	0.67
347_A	350_R	0.889	0.67
134_L	422_V	0.884	0.66
194_Q	329_T	0.884	0.66
524_L	528_D	0.882	0.66
429_L	432_Q	0.880	0.66
157_T	185_D	0.878	0.66
434_E	438_V	0.875	0.66
307_M	311_K	0.875	0.66
40_L	59_E	0.874	0.65
284_R	367_E	0.871	0.65
153_N	389_M	0.870	0.65
351_Q	355_E	0.869	0.65
3_A	6_V	0.866	0.65
461_E	466_A	0.861	0.64
17_L	100_I	0.857	0.64
175_I	407_V	0.854	0.64
3_A	524_L	0.853	0.64
224_D	300_V	0.853	0.64
264_V	268_R	0.853	0.64
326_N	380_K	0.853	0.64
205_I	211_G	0.852	0.63
124_V	504_L	0.851	0.63
181_T	185_D	0.849	0.63
62_L	67_E	0.848	0.63
236_V	312_A	0.847	0.63
220_I	332_I	0.846	0.63
8_F	183_L	0.843	0.63
130_E	422_V	0.841	0.62
41_D	66_F	0.839	0.62
247_L	273_V	0.836	0.62
224_D	307_M	0.833	0.62
383_A	515_I	0.833	0.62
243_A	246_P	0.832	0.62
50_T	153_N	0.832	0.62
243_A	314_L	0.831	0.62
523_D	529_A	0.831	0.62
122_K	440_I	0.825	0.61
302_S	307_M	0.824	0.61
455_V	465_V	0.821	0.61
74_V	514_M	0.817	0.60
124_V	443_A	0.816	0.60
37_N	516_T	0.814	0.60
526_K	529_A	0.813	0.60
52_D	55_S	0.813	0.60
300_V	305_I	0.812	0.60
41_D	523_D	0.811	0.60
448_E	461_E	0.811	0.60
261_T	264_V	0.809	0.59
107_V	116_L	0.807	0.59
482_T	493_I	0.806	0.59
49_I	387_V	0.805	0.59
114_M	512_G	0.800	0.59
324_V	333_I	0.796	0.58
230_I	234_L	0.796	0.58
424_S	470_K	0.795	0.58
417_V	469_V	0.794	0.58
531_D	535_A	0.794	0.58
43_S	526_K	0.793	0.58
123_A	440_I	0.790	0.58
11_D	14_V	0.790	0.58
50_T	75_K	0.788	0.57
420_I	466_A	0.787	0.57
524_L	530_A	0.783	0.57
472_G	485_Y	0.783	0.57
290_Q	304_E	0.783	0.57
40_L	55_S	0.783	0.57
7_K	41_D	0.782	0.57
424_S	428_D	0.782	0.57
486_G	490_D	0.779	0.57
290_Q	348_Q	0.779	0.57
254_V	275_A	0.774	0.56
469_V	472_G	0.771	0.56
301_I	313_T	0.771	0.56
65_K	525_P	0.767	0.55
153_N	391_E	0.767	0.55
346_V	369_V	0.766	0.55
240_V	247_L	0.766	0.55
529_A	533_G	0.764	0.55
54_V	57_A	0.763	0.55
18_R	21_N	0.763	0.55
183_L	186_E	0.763	0.55
452_R	463_S	0.760	0.55
236_V	240_V	0.757	0.54
116_L	443_A	0.757	0.54
432_Q	440_I	0.757	0.54
20_V	74_V	0.756	0.54
48_T	397_E	0.756	0.54
5_D	15_K	0.756	0.54
7_K	520_M	0.756	0.54
293_A	300_V	0.749	0.54
134_L	413_A	0.745	0.53
263_V	404_R	0.744	0.53
180_G	230_I	0.743	0.53
55_S	59_E	0.743	0.53
137_P	140_D	0.742	0.53
21_N	24_A	0.742	0.53
423_A	448_E	0.741	0.53
82_N	502_S	0.740	0.53
56_V	204_F	0.739	0.53
161_L	185_D	0.739	0.53
65_K	177_V	0.738	0.53
164_E	168_K	0.737	0.52
126_A	440_I	0.735	0.52
29_V	519_C	0.735	0.52
155_D	392_K	0.733	0.52
142_K	392_K	0.733	0.52
72_Q	404_R	0.732	0.52
14_V	17_L	0.732	0.52
251_A	254_V	0.731	0.52
99_I	514_M	0.729	0.52
162_I	379_I	0.729	0.52
141_S	163_A	0.728	0.52
413_A	417_V	0.727	0.51
321_K	336_V	0.725	0.51
424_S	473_D	0.725	0.51
218_P	245_K	0.722	0.51
527_N	533_G	0.722	0.51
479_N	488_M	0.720	0.51
122_K	126_A	0.719	0.51
449_A	452_R	0.718	0.51
356_A	369_V	0.717	0.50
237_L	243_A	0.716	0.50
412_V	418_A	0.715	0.50
215_L	323_V	0.715	0.50
445_R	448_E	0.714	0.50
428_D	431_G	0.713	0.50
26_A	519_C	0.713	0.50
228_S	254_V	0.709	0.50
473_D	476_Y	0.708	0.50
5_D	65_K	0.707	0.49
293_A	298_G	0.707	0.49
114_M	117_K	0.707	0.49
180_G	183_L	0.707	0.49
420_I	448_E	0.704	0.49
219_F	240_V	0.704	0.49
82_N	148_G	0.703	0.49
127_A	427_A	0.702	0.49
351_Q	354_E	0.701	0.49
298_G	316_D	0.700	0.49
148_G	250_I	0.700	0.49
39_V	56_V	0.699	0.49
479_N	484_E	0.699	0.49
223_A	252_E	0.697	0.48
418_A	497_T	0.696	0.48
58_R	225_K	0.692	0.48
531_D	536_G	0.692	0.48
432_Q	437_N	0.691	0.48
34_K	483_E	0.687	0.47
430_R	444_L	0.687	0.47
417_V	476_Y	0.687	0.47
16_M	100_I	0.684	0.47
443_A	447_M	0.683	0.47
241_A	270_I	0.683	0.47
157_T	164_E	0.681	0.47
440_I	444_L	0.681	0.47
482_T	486_G	0.681	0.47
22_V	63_E	0.681	0.47
276_V	325_I	0.680	0.47
41_D	242_K	0.679	0.47
248_L	276_V	0.679	0.47
94_V	449_A	0.679	0.47
333_I	518_E	0.678	0.47
224_D	302_S	0.678	0.47
426_L	431_G	0.676	0.46
418_A	422_V	0.676	0.46
506_Y	515_I	0.676	0.46
7_K	11_D	0.673	0.46
502_S	505_Q	0.671	0.46
183_L	384_A	0.671	0.46
443_A	493_I	0.671	0.46
278_A	289_L	0.669	0.46
422_V	447_M	0.669	0.46
19_G	70_G	0.668	0.46
125_T	505_Q	0.667	0.46
144_I	407_V	0.665	0.45
84_A	502_S	0.664	0.45
16_M	22_V	0.661	0.45
118_R	436_Q	0.660	0.45
466_A	469_V	0.659	0.45
233_M	236_V	0.658	0.45
343_Q	346_V	0.658	0.45
529_A	535_A	0.658	0.45
100_I	224_D	0.657	0.45
267_M	482_T	0.657	0.45
221_L	247_L	0.656	0.44
135_S	336_V	0.653	0.44
214_E	324_V	0.653	0.44
215_L	246_P	0.653	0.44
443_A	511_A	0.652	0.44
530_A	535_A	0.651	0.44
465_V	480_A	0.651	0.44
500_T	519_C	0.651	0.44
7_K	99_I	0.650	0.44
238_E	242_K	0.650	0.44
13_R	518_E	0.650	0.44
161_L	446_A	0.650	0.44
234_L	241_A	0.649	0.44
200_L	253_D	0.649	0.44
527_N	531_D	0.649	0.44
132_K	497_T	0.648	0.44
463_S	467_N	0.648	0.44
5_D	14_V	0.648	0.44
8_F	22_V	0.647	0.44
180_G	186_E	0.647	0.44
436_Q	440_I	0.647	0.44
423_A	444_L	0.645	0.43
525_P	530_A	0.645	0.43
68_N	72_Q	0.644	0.43
441_K	445_R	0.643	0.43
182_G	321_K	0.641	0.43
239_A	243_A	0.641	0.43
476_Y	485_Y	0.641	0.43
20_V	100_I	0.641	0.43
126_A	130_E	0.641	0.43
42_K	48_T	0.639	0.43
419_L	423_A	0.639	0.43
248_L	255_E	0.638	0.43
66_F	69_M	0.637	0.43
422_V	425_K	0.637	0.43
177_V	396_V	0.637	0.43
529_A	534_A	0.636	0.43
378_V	510_V	0.632	0.42
56_V	401_H	0.632	0.42
16_M	520_M	0.631	0.42
420_I	513_L	0.631	0.42
14_V	389_M	0.630	0.42
190_V	400_L	0.630	0.42
31_L	91_T	0.626	0.42
290_Q	302_S	0.625	0.41
146_Q	187_L	0.625	0.41
134_L	474_G	0.625	0.41
449_A	453_Q	0.624	0.41
129_E	240_V	0.623	0.41
127_A	444_L	0.623	0.41
56_V	153_N	0.621	0.41
383_A	392_K	0.621	0.41
431_G	434_E	0.621	0.41
122_K	487_N	0.620	0.41
184_Q	204_F	0.619	0.41
348_Q	355_E	0.619	0.41
219_F	314_L	0.616	0.41
452_R	456_L	0.615	0.40
60_I	521_V	0.615	0.40
69_M	400_L	0.614	0.40
217_S	321_K	0.614	0.40
209_E	390_K	0.614	0.40
217_S	428_D	0.614	0.40
528_D	531_D	0.613	0.40
100_I	440_I	0.612	0.40
286_K	304_E	0.612	0.40
82_N	150_I	0.612	0.40
210_T	494_L	0.611	0.40
368_R	410_G	0.610	0.40
443_A	508_A	0.609	0.40
181_T	184_Q	0.609	0.40
50_T	90_T	0.609	0.40
248_L	323_V	0.608	0.40
148_G	407_V	0.608	0.40
132_K	135_S	0.607	0.40
193_M	371_K	0.605	0.40
223_A	233_M	0.605	0.40
99_I	508_A	0.604	0.39
43_S	510_V	0.604	0.39
294_T	326_N	0.604	0.39
69_M	72_Q	0.603	0.39
8_F	18_R	0.603	0.39
239_A	314_L	0.602	0.39
477_G	488_M	0.602	0.39
50_T	56_V	0.602	0.39
220_I	323_V	0.600	0.39
326_N	331_T	0.600	0.39
39_V	514_M	0.600	0.39
224_D	360_Y	0.600	0.39
246_P	513_L	0.599	0.39
262_L	273_V	0.598	0.39
390_K	397_E	0.597	0.39
119_G	439_G	0.596	0.39
349_I	365_L	0.596	0.39
161_L	379_I	0.596	0.39
426_L	429_L	0.594	0.38
436_Q	449_A	0.594	0.38
264_V	302_S	0.593	0.38
299_T	307_M	0.592	0.38
40_L	60_I	0.592	0.38
115_D	435_D	0.592	0.38
304_E	311_K	0.591	0.38
294_T	338_E	0.591	0.38
141_S	184_Q	0.591	0.38
417_V	451_L	0.590	0.38
346_V	424_S	0.589	0.38
179_D	389_M	0.589	0.38
6_V	26_A	0.588	0.38
318_G	410_G	0.588	0.38
299_T	312_A	0.587	0.38
40_L	260_A	0.587	0.38
106_A	109_A	0.585	0.38
99_I	442_V	0.585	0.38
421_R	424_S	0.584	0.38
166_M	403_T	0.584	0.38
131_L	448_E	0.583	0.37
391_E	394_A	0.583	0.37
474_G	487_N	0.581	0.37
283_D	286_K	0.581	0.37
290_Q	299_T	0.581	0.37
9_G	63_E	0.580	0.37
7_K	10_N	0.578	0.37
224_D	304_E	0.578	0.37
166_M	400_L	0.578	0.37
427_A	431_G	0.578	0.37
468_T	484_E	0.577	0.37
51_K	100_I	0.577	0.37
237_L	241_A	0.576	0.37
7_K	524_L	0.575	0.37
144_I	408_E	0.575	0.37
291_D	368_R	0.574	0.37
153_N	274_A	0.574	0.37
105_K	295_L	0.573	0.37
98_A	449_A	0.573	0.37
51_K	204_F	0.572	0.36
72_Q	520_M	0.572	0.36
74_V	77_V	0.572	0.36
342_I	357_T	0.571	0.36
207_K	212_A	0.571	0.36
340_A	456_L	0.571	0.36
202_P	392_K	0.570	0.36
127_A	130_E	0.569	0.36
434_E	440_I	0.568	0.36
176_T	378_V	0.568	0.36
149_T	177_V	0.566	0.36
451_L	467_N	0.566	0.36
124_V	128_V	0.566	0.36
344_G	356_A	0.566	0.36
48_T	240_V	0.566	0.36
55_S	216_E	0.565	0.36
131_L	419_L	0.565	0.36
127_A	425_K	0.565	0.36
23_L	92_A	0.564	0.36
183_L	380_K	0.563	0.36
150_I	493_I	0.563	0.36
430_R	441_K	0.563	0.36
167_D	519_C	0.563	0.36
69_M	182_G	0.562	0.36
187_L	248_L	0.561	0.35
176_T	349_I	0.560	0.35
116_L	426_L	0.559	0.35
65_K	526_K	0.559	0.35
202_P	304_E	0.558	0.35
90_T	398_D	0.556	0.35
214_E	273_V	0.556	0.35
130_E	424_S	0.555	0.35
133_A	338_E	0.555	0.35
157_T	465_V	0.555	0.35
182_G	435_D	0.554	0.35
231_R	283_D	0.554	0.35
417_V	478_Y	0.554	0.35
448_E	463_S	0.554	0.35
111_M	520_M	0.553	0.35
148_G	467_N	0.553	0.35
156_E	533_G	0.552	0.35
105_K	108_A	0.552	0.35
529_A	536_G	0.551	0.35
115_D	521_V	0.551	0.35
63_E	526_K	0.550	0.34
445_R	452_R	0.550	0.34
303_E	311_K	0.550	0.34
222_L	326_N	0.550	0.34
73_M	510_V	0.550	0.34
232_E	270_I	0.549	0.34
484_E	490_D	0.549	0.34
248_L	350_R	0.549	0.34
188_D	530_A	0.548	0.34
53_G	89_T	0.547	0.34
57_A	89_T	0.547	0.34
475_N	489_I	0.547	0.34
156_E	481_A	0.546	0.34
204_F	262_L	0.546	0.34
107_V	481_A	0.546	0.34
16_M	321_K	0.545	0.34
94_V	98_A	0.545	0.34
80_K	84_A	0.544	0.34
449_A	456_L	0.544	0.34
469_V	527_N	0.544	0.34
145_A	156_E	0.544	0.34
71_A	92_A	0.544	0.34
338_E	437_N	0.543	0.34
451_L	485_Y	0.543	0.34
272_K	426_L	0.543	0.34
260_A	365_L	0.542	0.34
353_I	366_Q	0.542	0.34
81_A	411_V	0.542	0.34
161_L	216_E	0.542	0.34
421_R	476_Y	0.541	0.34
60_I	74_V	0.540	0.34
300_V	312_A	0.539	0.33
149_T	324_V	0.539	0.33
173_G	450_P	0.538	0.33
468_T	485_Y	0.537	0.33
42_K	361_D	0.537	0.33
17_L	514_M	0.537	0.33
115_D	197_R	0.536	0.33
98_A	446_A	0.536	0.33
14_V	18_R	0.536	0.33
298_G	349_I	0.535	0.33
140_D	422_V	0.535	0.33
162_I	166_M	0.534	0.33
202_P	260_A	0.533	0.33
134_L	418_A	0.533	0.33
230_I	350_R	0.533	0.33
180_G	209_E	0.532	0.33
144_I	166_M	0.532	0.33
72_Q	234_L	0.532	0.33
57_A	391_E	0.532	0.33
291_D	410_G	0.531	0.33
100_I	274_A	0.530	0.33
455_V	458_C	0.530	0.33
138_C	143_A	0.529	0.33
22_V	473_D	0.529	0.33
241_A	271_V	0.528	0.33
503_A	510_V	0.527	0.32
391_E	422_V	0.527	0.32
140_D	493_I	0.527	0.32
257_E	261_T	0.527	0.32
203_Y	327_K	0.527	0.32
137_P	143_A	0.527	0.32
304_E	308_E	0.526	0.32
22_V	220_I	0.526	0.32
300_V	307_M	0.526	0.32
100_I	513_L	0.525	0.32
82_N	402_A	0.525	0.32
246_P	274_A	0.524	0.32
240_V	244_G	0.524	0.32
389_M	392_K	0.524	0.32
141_S	161_L	0.523	0.32
210_T	230_I	0.523	0.32
456_L	462_P	0.523	0.32
129_E	428_D	0.523	0.32
530_A	534_A	0.523	0.32
528_D	533_G	0.523	0.32
246_P	325_I	0.523	0.32
385_T	510_V	0.522	0.32
118_R	512_G	0.522	0.32
303_E	309_L	0.522	0.32
39_V	326_N	0.522	0.32
134_L	421_R	0.522	0.32
212_A	326_N	0.520	0.32
58_R	203_Y	0.519	0.32
9_G	514_M	0.518	0.32
292_I	298_G	0.518	0.32
329_T	527_N	0.518	0.32
208_P	267_M	0.518	0.32
41_D	65_K	0.517	0.32
417_V	474_G	0.516	0.31
7_K	522_T	0.516	0.31
328_D	351_Q	0.515	0.31
386_E	393_K	0.515	0.31
277_K	283_D	0.515	0.31
357_T	361_D	0.515	0.31
297_G	336_V	0.513	0.31
16_M	69_M	0.513	0.31
32_G	88_G	0.513	0.31
361_D	364_K	0.512	0.31
127_A	441_K	0.512	0.31
350_R	369_V	0.512	0.31
218_P	319_Q	0.512	0.31
119_G	492_G	0.512	0.31
96_A	155_D	0.511	0.31
178_E	284_R	0.511	0.31
38_V	519_C	0.511	0.31
112_N	407_V	0.511	0.31
143_A	401_H	0.510	0.31
170_G	419_L	0.510	0.31
413_A	475_N	0.509	0.31
187_L	194_Q	0.509	0.31
37_N	153_N	0.509	0.31
186_E	233_M	0.509	0.31
122_K	216_E	0.509	0.31
185_D	392_K	0.508	0.31
55_S	82_N	0.508	0.31
101_T	505_Q	0.508	0.31
194_Q	205_I	0.507	0.31
217_S	317_L	0.507	0.31
70_G	477_G	0.507	0.31
298_G	341_A	0.507	0.31
379_I	520_M	0.507	0.31
25_D	29_V	0.507	0.31
453_Q	456_L	0.507	0.31
338_E	428_D	0.506	0.31
426_L	471_G	0.505	0.31
93_T	498_K	0.505	0.31
77_V	92_A	0.504	0.30
233_M	249_I	0.504	0.30
465_V	478_Y	0.504	0.30
285_R	361_D	0.504	0.30
130_E	270_I	0.504	0.30
472_G	475_N	0.504	0.30
231_R	360_Y	0.504	0.30
116_L	125_T	0.504	0.30
233_M	240_V	0.503	0.30
242_K	271_V	0.502	0.30
53_G	57_A	0.502	0.30
169_V	173_G	0.502	0.30
58_R	79_S	0.502	0.30
111_M	138_C	0.501	0.30
231_R	264_V	0.501	0.30
383_A	408_E	0.501	0.30
106_A	515_I	0.501	0.30
466_A	470_K	0.501	0.30
220_I	298_G	0.501	0.30
82_N	420_I	0.501	0.30
284_R	363_E	0.500	0.30
43_S	527_N	0.500	0.30

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1kp8A	5	0.958	100	0.156	Contact Map
1iokA	5	0.8777	100	0.158	Contact Map
3rtkA	2	0.8193	100	0.174	Contact Map
1we3A	5	0.9562	100	0.184	Contact Map
4pj1A	6	0.958	100	0.2	Contact Map
3ruvA	6	0.8431	100	0.322	Contact Map
1q3qA	4	0.8449	100	0.334	Contact Map
1a6dA	2	0.8285	100	0.339	Contact Map
3p9dC	1	0.8376	100	0.342	Contact Map
3j1bA	4	0.8358	100	0.345	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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