GLPK - ECOLI - GREMLIN Contacts

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GLPK - Glycerol kinase

UniProt:	P0A6F3	Sequences: MTEKKYIVALDQGTTSSRAVVMDHDANIISVSQREFEQIYPKPGWVEHDPMEIWATQSSTLVEVLAKADISSDQIAAIGITNQRETTIVWEKETGKPIYNAIVWQCRRTAEICEHLKRDGLEDYIRSNTGLVIDPYFSGTKVKWILDHVEGSRERARRGELLFGTVDTWLIWKMTQGRVHVTDYTNASRTMLFNIHTLDWDDKMLEVLDIPREMLPEVRRSSEVYGQTNIGGKGGTRIPISGIAGDQQAALFGQLCVKEGMAKNTYGTGCFMLMNTGEKAVKSENGLLTTIACGPTGEVNYALEGAVFMAGASIQWLRDEMKLINDAYDSEYFATKVQNTNGVYVVPAFTGLGAPYWDPYARGAIFGLTRGVNANHIIRATLESIAYQTRDVLEAMQADSGIRLHALRVDGGAVANNFLMQFQSDILGTRVERPEVREVTALGAAYLAGLAVGFWQNLDELQEKAVIEREFRPGIETTERNYRYAGWKKAVKRAMAWEEHDE	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10398
Length:	502 (474)
Sequences:	12568 (8647)
Seq/√Len:	397.2

ECOLI - GLPK LYXK ARAB XYLB LSRK RHAB FUCK YGCE
BACSU - GLPK XYLB GNTK ARAB YOAC RHAB
HALSA - GLPK
SULSO - GLPK2 GLPK1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
202_D	212_R	4.040	1.00
112_I	147_D	3.791	1.00
23_D	27_N	3.480	1.00
19_A	60_T	3.289	1.00
115_H	147_D	3.262	1.00
194_N	197_T	2.887	1.00
390_R	484_Y	2.868	1.00
430_R	472_R	2.846	1.00
390_R	394_E	2.811	1.00
397_Q	429_T	2.767	1.00
128_N	201_D	2.764	1.00
34_R	59_S	2.709	1.00
457_N	460_E	2.691	1.00
417_N	469_R	2.656	1.00
421_Q	425_D	2.650	1.00
365_I	377_I	2.648	1.00
39_I	100_N	2.629	1.00
98_I	152_S	2.604	1.00
406_A	432_E	2.567	1.00
34_R	63_E	2.557	1.00
456_Q	460_E	2.549	1.00
193_F	218_V	2.547	1.00
220_R	223_E	2.544	1.00
32_S	63_E	2.543	1.00
21_V	64_V	2.490	1.00
99_Y	149_V	2.476	1.00
91_E	155_R	2.439	1.00
51_M	173_K	2.407	1.00
179_V	217_E	2.404	1.00
54_W	173_K	2.397	1.00
92_K	157_R	2.367	1.00
199_D	212_R	2.346	1.00
390_R	481_N	2.325	1.00
326_D	329_D	2.313	1.00
205_L	212_R	2.291	1.00
91_E	94_T	2.268	1.00
194_N	201_D	2.207	1.00
202_D	206_E	2.165	1.00
58_S	235_G	2.163	1.00
325_N	329_D	2.125	1.00
341_N	376_H	2.123	1.00
10_L	57_Q	2.123	1.00
244_A	249_A	2.091	1.00
171_I	243_I	2.087	1.00
20_V	441_A	2.084	1.00
474_G	477_T	2.002	1.00
313_S	381_T	1.992	1.00
16_S	33_Q	1.991	1.00
115_H	119_D	1.934	1.00
327_A	330_S	1.929	1.00
124_Y	127_S	1.911	1.00
229_N	232_G	1.905	1.00
51_M	96_K	1.897	1.00
63_E	67_K	1.895	1.00
37_E	52_E	1.892	1.00
270_C	310_A	1.890	1.00
397_Q	403_R	1.874	1.00
373_N	376_H	1.858	1.00
175_T	240_I	1.846	1.00
8_V	61_L	1.842	1.00
7_I	449_G	1.836	1.00
344_Y	486_G	1.834	1.00
409_V	420_M	1.813	1.00
158_R	180_H	1.809	1.00
6_Y	29_I	1.805	1.00
336_K	375_N	1.795	1.00
484_Y	488_K	1.786	1.00
230_I	236_T	1.781	1.00
345_V	365_I	1.779	1.00
12_Q	17_S	1.768	1.00
143_K	147_D	1.768	1.00
8_V	19_A	1.767	1.00
428_G	478_T	1.762	1.00
42_K	45_W	1.752	1.00
317_L	381_T	1.726	1.00
219_R	223_E	1.716	1.00
432_E	470_E	1.711	1.00
6_Y	21_V	1.711	1.00
128_N	203_K	1.700	1.00
241_S	451_A	1.700	1.00
124_Y	128_N	1.694	1.00
425_D	477_T	1.663	1.00
124_Y	203_K	1.662	1.00
114_E	118_R	1.661	1.00
425_D	474_G	1.661	1.00
430_R	470_E	1.650	1.00
95_G	172_W	1.633	1.00
261_M	406_A	1.625	1.00
89_V	145_I	1.620	1.00
224_V	227_Q	1.619	1.00
329_D	332_Y	1.610	1.00
315_Q	319_D	1.599	1.00
230_I	234_G	1.593	1.00
181_V	219_R	1.591	1.00
91_E	96_K	1.590	1.00
387_Y	483_R	1.580	1.00
88_I	166_V	1.553	1.00
89_V	214_M	1.543	1.00
117_K	122_E	1.541	1.00
224_V	241_S	1.539	1.00
111_E	115_H	1.537	1.00
259_E	277_G	1.533	1.00
362_R	369_T	1.514	1.00
151_G	154_E	1.503	1.00
7_I	454_F	1.489	1.00
394_E	488_K	1.474	1.00
32_S	60_T	1.435	1.00
39_I	52_E	1.435	1.00
478_T	481_N	1.430	1.00
435_E	468_E	1.425	1.00
394_E	397_Q	1.425	1.00
476_E	479_E	1.423	1.00
123_D	127_S	1.423	1.00
32_S	64_V	1.414	1.00
30_S	64_V	1.409	1.00
65_L	72_S	1.406	1.00
54_W	58_S	1.405	1.00
331_E	334_A	1.404	1.00
331_E	335_T	1.400	1.00
49_D	52_E	1.398	1.00
171_I	225_Y	1.390	1.00
333_F	337_V	1.387	1.00
333_F	336_K	1.386	1.00
227_Q	237_R	1.383	1.00
144_W	148_H	1.374	1.00
418_F	422_F	1.368	1.00
449_G	455_W	1.363	1.00
379_R	383_E	1.359	1.00
417_N	433_R	1.354	1.00
417_N	471_F	1.348	1.00
30_S	67_K	1.337	1.00
345_V	349_F	1.335	1.00
10_L	61_L	1.332	1.00
332_Y	335_T	1.332	1.00
77_A	448_A	1.325	1.00
386_A	422_F	1.318	1.00
224_V	239_P	1.317	1.00
51_M	55_A	1.313	1.00
169_W	173_K	1.311	1.00
175_T	226_G	1.301	1.00
90_W	164_G	1.297	1.00
337_V	376_H	1.291	1.00
307_V	388_Q	1.290	1.00
262_A	404_L	1.289	1.00
477_T	480_R	1.278	1.00
71_S	74_Q	1.276	1.00
266_Y	423_Q	1.272	1.00
184_Y	198_L	1.271	1.00
406_A	430_R	1.267	1.00
420_M	471_F	1.263	1.00
428_G	480_R	1.261	1.00
433_R	471_F	1.258	1.00
211_P	214_M	1.256	1.00
343_V	372_V	1.249	1.00
84_R	245_G	1.248	1.00
386_A	423_Q	1.247	1.00
110_A	114_E	1.247	1.00
24_H	454_F	1.242	1.00
112_I	143_K	1.242	1.00
368_L	372_V	1.242	1.00
386_A	426_I	1.238	1.00
17_S	57_Q	1.236	1.00
219_R	225_Y	1.228	1.00
415_A	437_R	1.227	1.00
55_A	59_S	1.226	1.00
205_L	215_L	1.222	1.00
21_V	70_I	1.216	1.00
264_N	423_Q	1.212	1.00
345_V	381_T	1.199	1.00
139_G	208_L	1.197	1.00
124_Y	207_V	1.192	1.00
119_D	207_V	1.188	1.00
125_I	133_I	1.184	1.00
95_G	180_H	1.182	1.00
146_L	153_R	1.182	1.00
171_I	181_V	1.173	1.00
422_F	426_I	1.171	1.00
244_A	447_L	1.167	1.00
49_D	100_N	1.162	1.00
479_E	482_Y	1.162	1.00
17_S	56_T	1.160	1.00
394_E	484_Y	1.148	1.00
203_K	206_E	1.140	1.00
278_E	298_E	1.139	1.00
428_G	481_N	1.139	1.00
332_Y	336_K	1.134	1.00
391_D	488_K	1.134	1.00
86_T	101_A	1.133	1.00
149_V	152_S	1.132	1.00
22_M	28_I	1.129	1.00
390_R	427_L	1.124	1.00
321_M	377_I	1.123	1.00
59_S	63_E	1.121	1.00
258_K	261_M	1.112	1.00
10_L	19_A	1.110	1.00
179_V	219_R	1.110	1.00
184_Y	218_V	1.101	1.00
57_Q	170_L	1.098	1.00
6_Y	74_Q	1.098	1.00
89_V	156_A	1.096	1.00
50_P	88_I	1.093	1.00
467_I	470_E	1.092	1.00
258_K	459_D	1.087	1.00
196_H	280_A	1.084	1.00
309_M	313_S	1.082	1.00
224_V	451_A	1.078	1.00
184_Y	193_F	1.077	1.00
70_I	74_Q	1.077	1.00
47_E	100_N	1.075	1.00
261_M	408_R	1.074	1.00
474_G	478_T	1.070	1.00
258_K	462_Q	1.070	1.00
121_L	207_V	1.065	1.00
481_N	485_A	1.065	1.00
156_A	214_M	1.054	1.00
63_E	66_A	1.050	1.00
77_A	452_V	1.048	1.00
113_C	133_I	1.048	1.00
366_F	490_A	1.046	1.00
164_G	180_H	1.046	1.00
446_Y	461_L	1.043	1.00
89_V	142_V	1.041	1.00
151_G	155_R	1.036	1.00
7_I	452_V	1.035	1.00
330_S	378_I	1.030	1.00
62_V	235_G	1.028	1.00
486_G	489_K	1.028	1.00
22_M	445_A	1.026	1.00
372_V	376_H	1.026	1.00
111_E	114_E	1.026	1.00
114_E	117_K	1.025	1.00
460_E	463_E	1.021	1.00
408_R	432_E	1.020	1.00
78_I	238_I	1.017	1.00
205_L	210_I	1.016	1.00
193_F	197_T	1.016	1.00
181_V	225_Y	1.015	1.00
53_I	166_V	1.013	1.00
435_E	466_V	1.012	1.00
38_Q	48_H	1.011	1.00
449_G	454_F	1.010	1.00
450_L	461_L	1.009	1.00
182_T	187_A	1.008	1.00
393_L	427_L	1.006	1.00
99_Y	152_S	1.004	1.00
108_R	144_W	1.003	1.00
112_I	148_H	1.002	1.00
260_G	405_H	1.000	1.00
231_G	235_G	1.000	1.00
6_Y	70_I	1.000	1.00
262_A	274_M	0.999	1.00
313_S	345_V	0.997	1.00
57_Q	61_L	0.997	1.00
385_I	413_A	0.996	1.00
121_L	124_Y	0.995	1.00
112_I	115_H	0.992	1.00
387_Y	426_I	0.989	1.00
80_I	171_I	0.985	1.00
227_Q	239_P	0.982	1.00
52_E	55_A	0.981	1.00
7_I	77_A	0.978	1.00
363_G	368_L	0.975	1.00
77_A	241_S	0.974	1.00
152_S	155_R	0.974	1.00
62_V	66_A	0.971	1.00
139_G	191_M	0.967	1.00
309_M	312_A	0.967	1.00
345_V	380_A	0.965	1.00
36_F	56_T	0.964	1.00
32_S	67_K	0.964	1.00
153_R	156_A	0.963	1.00
58_S	62_V	0.961	1.00
379_R	418_F	0.960	1.00
115_H	118_R	0.958	1.00
8_V	21_V	0.952	1.00
198_L	220_R	0.949	1.00
258_K	463_E	0.949	1.00
142_V	163_F	0.949	1.00
390_R	426_I	0.947	1.00
125_I	191_M	0.944	1.00
46_V	105_Q	0.943	1.00
277_G	300_N	0.937	1.00
76_A	452_V	0.935	1.00
331_E	417_N	0.932	1.00
406_A	470_E	0.931	1.00
150_E	154_E	0.931	1.00
19_A	64_V	0.929	1.00
81_T	440_T	0.928	1.00
475_I	480_R	0.926	1.00
65_L	75_I	0.924	1.00
80_I	170_L	0.924	1.00
96_K	173_K	0.923	1.00
455_W	461_L	0.922	1.00
258_K	405_H	0.921	1.00
413_A	419_L	0.919	1.00
241_S	452_V	0.915	1.00
263_K	410_D	0.909	1.00
145_I	152_S	0.905	1.00
22_M	442_L	0.905	1.00
127_S	196_H	0.902	1.00
339_N	342_G	0.900	1.00
23_D	29_I	0.899	1.00
8_V	75_I	0.898	1.00
475_I	478_T	0.896	1.00
334_A	418_F	0.896	1.00
427_L	430_R	0.894	1.00
334_A	337_V	0.893	1.00
89_V	163_F	0.893	1.00
272_M	393_L	0.887	1.00
168_T	182_T	0.887	1.00
87_T	163_F	0.878	1.00
199_D	217_E	0.877	1.00
407_L	427_L	0.877	1.00
446_Y	465_A	0.876	1.00
228_T	233_K	0.875	1.00
387_Y	484_Y	0.874	1.00
198_L	299_V	0.873	1.00
75_I	238_I	0.872	1.00
21_V	75_I	0.870	1.00
184_Y	220_R	0.869	1.00
394_E	398_A	0.866	1.00
127_S	282_K	0.864	1.00
270_C	389_T	0.864	1.00
275_N	300_N	0.863	1.00
157_R	213_E	0.862	1.00
362_R	366_F	0.861	1.00
352_L	355_P	0.860	1.00
99_Y	145_I	0.859	1.00
325_N	330_S	0.852	1.00
176_Q	229_N	0.848	1.00
333_F	375_N	0.848	1.00
115_H	143_K	0.847	1.00
358_D	361_A	0.843	1.00
143_K	146_L	0.842	1.00
324_I	330_S	0.842	1.00
79_G	241_S	0.841	1.00
181_V	217_E	0.838	1.00
156_A	163_F	0.837	1.00
12_Q	170_L	0.836	1.00
34_R	60_T	0.836	1.00
368_L	377_I	0.834	1.00
230_I	237_R	0.829	1.00
475_I	479_E	0.825	1.00
450_L	458_L	0.817	1.00
250_A	410_D	0.817	1.00
228_T	238_I	0.814	1.00
113_C	135_P	0.813	1.00
85_E	189_R	0.813	1.00
361_A	364_A	0.813	1.00
219_R	242_G	0.812	1.00
460_E	464_K	0.810	1.00
80_I	174_M	0.806	1.00
200_W	215_L	0.802	1.00
274_M	396_M	0.802	1.00
365_I	381_T	0.799	1.00
316_W	319_D	0.799	1.00
35_E	315_Q	0.799	1.00
107_R	134_D	0.797	1.00
76_A	454_F	0.797	1.00
421_Q	474_G	0.796	1.00
165_T	190_T	0.796	1.00
409_V	433_R	0.795	1.00
227_Q	236_T	0.794	1.00
113_C	140_T	0.793	1.00
333_F	378_I	0.790	1.00
92_K	155_R	0.790	1.00
271_F	306_A	0.789	1.00
117_K	133_I	0.787	1.00
199_D	202_D	0.787	1.00
22_M	436_V	0.786	1.00
382_L	422_F	0.784	1.00
111_E	147_D	0.782	1.00
331_E	337_V	0.782	1.00
247_Q	271_F	0.781	1.00
172_W	180_H	0.780	1.00
342_G	483_R	0.779	1.00
52_E	56_T	0.778	1.00
479_E	483_R	0.777	1.00
182_T	216_P	0.774	1.00
111_E	148_H	0.774	1.00
61_L	65_L	0.774	1.00
35_E	318_R	0.773	1.00
393_L	397_Q	0.773	1.00
432_E	467_I	0.772	1.00
77_A	239_P	0.770	1.00
414_V	437_R	0.770	1.00
72_S	75_I	0.770	1.00
90_W	95_G	0.769	1.00
489_K	492_K	0.768	1.00
262_A	407_L	0.766	1.00
317_L	378_I	0.765	1.00
28_I	31_V	0.763	1.00
187_A	200_W	0.762	1.00
337_V	340_T	0.762	1.00
382_L	416_N	0.761	1.00
326_D	330_S	0.761	1.00
344_Y	366_F	0.759	1.00
395_A	398_A	0.758	1.00
84_R	304_E	0.756	1.00
193_F	198_L	0.755	1.00
482_Y	485_A	0.755	1.00
482_Y	486_G	0.754	1.00
233_K	237_R	0.754	1.00
194_N	199_D	0.752	1.00
139_G	192_L	0.751	1.00
12_Q	57_Q	0.745	1.00
128_N	194_N	0.745	1.00
90_W	180_H	0.742	1.00
167_D	243_I	0.741	1.00
409_V	423_Q	0.739	1.00
264_N	270_C	0.734	1.00
65_L	70_I	0.734	1.00
36_F	48_H	0.732	1.00
264_N	389_T	0.731	1.00
206_E	212_R	0.730	1.00
34_R	56_T	0.729	1.00
50_P	100_N	0.728	1.00
91_E	157_R	0.727	1.00
328_Y	331_E	0.727	1.00
391_D	484_Y	0.726	1.00
203_K	207_V	0.725	1.00
78_I	228_T	0.723	1.00
331_E	416_N	0.723	1.00
154_E	158_R	0.721	1.00
317_L	377_I	0.718	1.00
41_P	45_W	0.718	1.00
254_Q	410_D	0.717	1.00
9_A	79_G	0.716	1.00
17_S	36_F	0.715	1.00
55_A	58_S	0.715	1.00
98_I	155_R	0.715	1.00
143_K	209_D	0.712	1.00
236_T	239_P	0.712	1.00
31_V	438_E	0.712	1.00
142_V	192_L	0.711	1.00
276_T	303_L	0.710	1.00
84_R	186_N	0.710	1.00
322_K	374_A	0.709	1.00
310_A	385_I	0.708	1.00
483_R	486_G	0.708	1.00
390_R	488_K	0.708	1.00
329_D	333_F	0.708	1.00
327_A	331_E	0.708	1.00
254_Q	263_K	0.707	1.00
14_T	103_V	0.706	1.00
386_A	419_L	0.705	1.00
201_D	204_M	0.705	1.00
361_A	365_I	0.704	1.00
104_W	269_G	0.704	1.00
305_G	392_V	0.702	1.00
341_N	372_V	0.700	1.00
264_N	407_L	0.699	1.00
477_T	481_N	0.698	1.00
25_D	464_K	0.697	1.00
95_G	157_R	0.692	1.00
51_M	97_P	0.692	1.00
125_I	204_M	0.690	1.00
250_A	440_T	0.689	1.00
387_Y	480_R	0.686	0.99
340_T	376_H	0.686	0.99
51_M	169_W	0.685	0.99
61_L	64_V	0.680	0.99
171_I	175_T	0.679	0.99
89_V	98_I	0.679	0.99
426_I	480_R	0.678	0.99
129_T	204_M	0.678	0.99
185_T	244_A	0.676	0.99
414_V	420_M	0.675	0.99
58_S	173_K	0.674	0.99
123_D	126_R	0.673	0.99
232_G	235_G	0.673	0.99
285_N	398_A	0.670	0.99
90_W	158_R	0.669	0.99
169_W	172_W	0.669	0.99
91_E	98_I	0.669	0.99
342_G	379_R	0.668	0.99
488_K	492_K	0.668	0.99
59_S	62_V	0.667	0.99
407_L	431_V	0.667	0.99
322_K	325_N	0.667	0.99
455_W	464_K	0.666	0.99
57_Q	60_T	0.666	0.99
47_E	108_R	0.665	0.99
231_G	234_G	0.664	0.99
12_Q	56_T	0.664	0.99
449_G	453_G	0.663	0.99
88_I	101_A	0.663	0.99
175_T	179_V	0.662	0.99
450_L	457_N	0.661	0.99
225_Y	242_G	0.661	0.99
446_Y	464_K	0.660	0.99
284_E	288_L	0.659	0.99
340_T	383_E	0.657	0.99
430_R	473_P	0.655	0.99
472_R	475_I	0.655	0.99
409_V	431_V	0.654	0.99
363_G	366_F	0.654	0.99
143_K	153_R	0.653	0.99
459_D	462_Q	0.653	0.99
433_R	468_E	0.652	0.99
256_C	261_M	0.652	0.99
20_V	28_I	0.651	0.99
114_E	360_Y	0.650	0.99
221_S	243_I	0.650	0.99
287_L	290_T	0.649	0.99
233_K	236_T	0.648	0.99
133_I	191_M	0.647	0.99
90_W	169_W	0.647	0.99
417_N	421_Q	0.645	0.99
206_E	211_P	0.644	0.99
22_M	441_A	0.644	0.99
246_D	268_T	0.643	0.99
51_M	100_N	0.643	0.99
467_I	473_P	0.643	0.99
307_V	392_V	0.642	0.99
50_P	101_A	0.642	0.99
317_L	321_M	0.642	0.99
405_H	429_T	0.639	0.99
24_H	76_A	0.639	0.99
7_I	76_A	0.638	0.99
346_V	364_A	0.637	0.99
383_E	422_F	0.636	0.99
182_T	218_V	0.636	0.99
351_G	355_P	0.635	0.99
340_T	344_Y	0.631	0.99
58_S	232_G	0.629	0.99
102_I	108_R	0.628	0.99
336_K	376_H	0.627	0.99
90_W	172_W	0.626	0.99
481_N	484_Y	0.626	0.99
286_G	303_L	0.625	0.99
407_L	429_T	0.625	0.99
82_N	186_N	0.624	0.99
224_V	452_V	0.622	0.99
435_E	467_I	0.621	0.99
116_L	208_L	0.620	0.99
143_K	208_L	0.620	0.99
421_Q	471_F	0.617	0.99
345_V	384_S	0.617	0.99
55_A	235_G	0.617	0.99
330_S	416_N	0.615	0.99
54_W	232_G	0.615	0.99
51_M	54_W	0.613	0.99
40_Y	46_V	0.610	0.99
146_L	209_D	0.610	0.99
270_C	423_Q	0.608	0.99
339_N	376_H	0.607	0.99
239_P	452_V	0.606	0.99
457_N	463_E	0.606	0.99
446_Y	450_L	0.605	0.99
461_L	465_A	0.605	0.99
416_N	419_L	0.604	0.99
273_L	302_A	0.604	0.99
342_G	383_E	0.604	0.99
227_Q	230_I	0.604	0.99
285_N	289_T	0.602	0.99
461_L	464_K	0.602	0.99
331_E	336_K	0.601	0.99
356_Y	391_D	0.598	0.99
379_R	422_F	0.598	0.99
355_P	358_D	0.598	0.99
196_H	199_D	0.597	0.99
406_A	429_T	0.595	0.99
420_M	433_R	0.595	0.99
102_I	145_I	0.592	0.99
168_T	180_H	0.591	0.99
82_N	166_V	0.591	0.99
155_R	158_R	0.590	0.98
131_L	137_F	0.589	0.98
398_A	488_K	0.589	0.98
87_T	138_S	0.589	0.98
436_V	442_L	0.589	0.98
342_G	376_H	0.588	0.98
450_L	455_W	0.587	0.98
196_H	279_K	0.586	0.98
422_F	480_R	0.586	0.98
428_G	475_I	0.585	0.98
58_S	61_L	0.585	0.98
83_Q	104_W	0.584	0.98
245_G	248_Q	0.581	0.98
110_A	135_P	0.579	0.98
450_L	453_G	0.578	0.98
343_V	380_A	0.577	0.98
28_I	436_V	0.575	0.98
86_T	103_V	0.575	0.98
340_T	379_R	0.574	0.98
404_L	429_T	0.573	0.98
328_Y	332_Y	0.572	0.98
116_L	140_T	0.572	0.98
270_C	307_V	0.572	0.98
247_Q	265_T	0.571	0.98
335_T	418_F	0.570	0.98
346_V	352_L	0.569	0.98
230_I	233_K	0.568	0.98
327_A	334_A	0.568	0.98
206_E	209_D	0.567	0.98
337_V	341_N	0.567	0.98
350_T	370_R	0.566	0.98
232_G	237_R	0.564	0.98
176_Q	231_G	0.563	0.98
210_I	215_L	0.563	0.98
339_N	379_R	0.562	0.98
346_V	490_A	0.562	0.98
284_E	287_L	0.561	0.98
346_V	491_V	0.561	0.98
108_R	148_H	0.561	0.98
142_V	214_M	0.561	0.98
264_N	272_M	0.561	0.98
356_Y	491_V	0.560	0.98
485_A	488_K	0.560	0.98
40_Y	43_P	0.560	0.98
137_F	189_R	0.558	0.98
323_L	329_D	0.558	0.98
458_L	462_Q	0.557	0.98
385_I	419_L	0.556	0.98
356_Y	488_K	0.556	0.98
290_T	302_A	0.554	0.98
185_T	221_S	0.553	0.98
348_A	352_L	0.553	0.98
266_Y	409_V	0.552	0.98
47_E	99_Y	0.552	0.98
341_N	371_G	0.552	0.98
78_I	240_I	0.551	0.98
251_L	273_L	0.551	0.98
432_E	468_E	0.551	0.98
255_L	465_A	0.550	0.98
109_T	140_T	0.550	0.98
253_G	439_V	0.550	0.98
88_I	97_P	0.547	0.98
325_N	328_Y	0.547	0.98
229_N	237_R	0.546	0.98
192_L	215_L	0.546	0.98
383_E	387_Y	0.546	0.98
322_K	329_D	0.544	0.97
7_I	455_W	0.543	0.97
421_Q	424_S	0.543	0.97
190_T	200_W	0.543	0.97
140_T	191_M	0.543	0.97
31_V	67_K	0.541	0.97
333_F	338_Q	0.541	0.97
95_G	158_R	0.541	0.97
27_N	435_E	0.540	0.97
343_V	368_L	0.539	0.97
6_Y	73_D	0.538	0.97
442_L	446_Y	0.537	0.97
272_M	392_V	0.537	0.97
329_D	337_V	0.536	0.97
221_S	244_A	0.536	0.97
153_R	211_P	0.535	0.97
462_Q	466_V	0.535	0.97
49_D	55_A	0.535	0.97
81_T	444_A	0.535	0.97
125_I	208_L	0.535	0.97
119_D	143_K	0.532	0.97
164_G	172_W	0.532	0.97
480_R	483_R	0.531	0.97
222_S	451_A	0.529	0.97
424_S	431_V	0.529	0.97
84_R	189_R	0.527	0.97
459_D	463_E	0.527	0.97
343_V	377_I	0.526	0.97
414_V	433_R	0.526	0.97
97_P	100_N	0.526	0.97
176_Q	179_V	0.526	0.97
252_F	446_Y	0.526	0.97
153_R	209_D	0.526	0.97
356_Y	361_A	0.525	0.97
274_M	404_L	0.525	0.97
320_E	373_N	0.524	0.97
45_W	102_I	0.524	0.97
15_T	18_R	0.523	0.97
196_H	282_K	0.522	0.97
261_M	405_H	0.522	0.97
422_F	483_R	0.522	0.97
276_T	280_A	0.521	0.97
261_M	462_Q	0.521	0.97
14_T	104_W	0.521	0.97
85_E	104_W	0.520	0.97
330_S	334_A	0.519	0.97
344_Y	387_Y	0.518	0.97
324_I	329_D	0.518	0.97
265_T	410_D	0.517	0.97
192_L	200_W	0.517	0.97
255_L	462_Q	0.517	0.97
423_Q	427_L	0.517	0.97
89_V	99_Y	0.516	0.97
314_I	330_S	0.514	0.96
325_N	374_A	0.513	0.96
242_G	249_A	0.512	0.96
462_Q	465_A	0.512	0.96
358_D	365_I	0.510	0.96
85_E	269_G	0.510	0.96
457_N	461_L	0.509	0.96
222_S	450_L	0.508	0.96
405_H	430_R	0.508	0.96
347_P	384_S	0.507	0.96
153_R	157_R	0.507	0.96
265_T	271_F	0.506	0.96
147_D	209_D	0.506	0.96
389_T	423_Q	0.505	0.96
279_K	301_Y	0.505	0.96
397_Q	404_L	0.505	0.96
289_T	292_A	0.504	0.96
193_F	200_W	0.504	0.96
165_T	186_N	0.502	0.96
204_M	208_L	0.501	0.96
46_V	103_V	0.501	0.96
315_Q	318_R	0.500	0.96
84_R	166_V	0.500	0.96
171_I	240_I	0.500	0.96
263_K	273_L	0.500	0.96

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3h3nX	3	0.998	100	0.133	Contact Map
3ezwA	3	0.994	100	0.133	Contact Map
3g25A	3	0.992	100	0.138	Contact Map
2d4wA	2	0.99	100	0.142	Contact Map
3ll3A	2	0.9661	100	0.144	Contact Map
3wxlA	2	0.988	100	0.145	Contact Map
2zf5O	3	0.9801	100	0.146	Contact Map
2dpnA	2	0.9801	100	0.149	Contact Map
2w40A	3	0.9801	100	0.156	Contact Map
2itmA	2	0.9382	100	0.161	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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