ARGB - ECOLI - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

ARGB - Acetylglutamate kinase

UniProt:	P0A6C8	Sequences: MMNPLIIKLGGVLLDSEEALERLFSALVNYRESHQRPLVIVHGGGCVVDELMKGLNLPVKKKNGLRVTPADQIDIITGALAGTANKTLLAWAKKHQIAAVGLFLGDGDSVKVTQLDEELGHVGLAQPGSPKLINSLLENGYLPVVSSIGVTDEGQLMNVNADQAATALAATLGADLILLSDVSGILDGKGQRIAEMTAAKAEQLIEQGIITDGMIVKVNAALDAARTLGRPVDIASWRHAEQLPALFNGMPMGTRILA	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10064
Length:	258 (251)
Sequences:	3503 (1986)
Seq/√Len:	125.3

ECOLI - ARGB ARGA
BACSU - ARGB
SULSO - ARGB

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
39_V	172_L	3.673	1.00
113_T	126_Q	3.638	1.00
69_P	72_Q	3.619	1.00
151_T	155_Q	3.454	1.00
113_T	124_L	3.146	1.00
110_V	164_A	3.117	1.00
183_S	236_S	2.981	1.00
202_E	226_R	2.891	1.00
70_A	121_H	2.879	1.00
198_A	222_L	2.609	1.00
4_P	36_R	2.583	1.00
3_N	175_D	2.570	1.00
145_V	168_L	2.508	1.00
111_K	127_P	2.414	1.00
114_Q	118_E	2.368	1.00
57_L	71_D	2.298	1.00
175_D	230_R	2.273	1.00
110_V	128_G	2.205	1.00
188_G	191_Q	2.164	1.00
203_Q	207_Q	2.111	1.00
231_P	255_R	2.110	1.00
92_A	144_V	2.097	1.00
53_K	58_P	2.062	1.00
149_G	159_V	2.049	1.00
202_E	206_E	2.018	1.00
51_L	55_L	2.006	1.00
201_A	222_L	2.004	1.00
112_V	149_G	1.947	1.00
5_L	35_Q	1.899	1.00
52_M	59_V	1.876	1.00
170_A	227_T	1.874	1.00
205_I	219_N	1.823	1.00
28_V	97_I	1.820	1.00
55_L	75_I	1.793	1.00
26_A	241_E	1.786	1.00
197_T	200_K	1.756	1.00
200_K	203_Q	1.752	1.00
114_Q	157_M	1.752	1.00
25_S	95_H	1.745	1.00
49_D	59_V	1.743	1.00
77_T	105_G	1.733	1.00
130_P	134_N	1.717	1.00
51_L	79_A	1.696	1.00
210_I	218_V	1.661	1.00
135_S	139_N	1.650	1.00
225_A	232_V	1.645	1.00
51_L	78_G	1.627	1.00
196_M	201_A	1.619	1.00
50_E	53_K	1.609	1.00
185_I	218_V	1.596	1.00
151_T	157_M	1.591	1.00
21_E	91_W	1.584	1.00
65_L	163_Q	1.542	1.00
187_D	191_Q	1.542	1.00
73_I	76_I	1.524	1.00
245_A	251_P	1.508	1.00
111_K	129_S	1.500	1.00
66_R	158_N	1.498	1.00
97_I	142_L	1.484	1.00
110_V	168_L	1.481	1.00
221_A	232_V	1.470	1.00
114_Q	117_E	1.458	1.00
248_N	251_P	1.432	1.00
183_S	186_L	1.427	1.00
186_L	192_R	1.394	1.00
76_I	148_I	1.392	1.00
115_L	124_L	1.388	1.00
62_K	67_V	1.388	1.00
60_K	67_V	1.345	1.00
133_I	168_L	1.339	1.00
55_L	78_G	1.330	1.00
50_E	54_G	1.312	1.00
81_A	103_F	1.305	1.00
29_N	33_S	1.300	1.00
4_P	134_N	1.292	1.00
112_V	157_M	1.286	1.00
60_K	69_P	1.285	1.00
20_L	87_T	1.270	1.00
73_I	148_I	1.267	1.00
218_V	222_L	1.264	1.00
100_V	136_L	1.262	1.00
188_G	209_I	1.250	1.00
121_H	155_Q	1.241	1.00
202_E	222_L	1.230	0.99
36_R	138_E	1.229	0.99
17_E	20_L	1.227	0.99
136_L	141_Y	1.222	0.99
134_N	138_E	1.220	0.99
202_E	219_N	1.218	0.99
85_N	89_L	1.204	0.99
185_I	196_M	1.202	0.99
111_K	152_D	1.200	0.99
74_D	83_T	1.193	0.99
168_L	172_L	1.189	0.99
49_D	61_K	1.184	0.99
148_I	156_L	1.182	0.99
167_A	170_A	1.177	0.99
133_I	145_V	1.166	0.99
105_G	156_L	1.159	0.99
132_L	135_S	1.158	0.99
36_R	137_L	1.156	0.99
178_L	220_A	1.149	0.99
12_V	46_C	1.147	0.99
21_E	94_K	1.146	0.99
21_E	95_H	1.146	0.99
92_A	97_I	1.131	0.99
54_G	74_D	1.125	0.99
195_E	255_R	1.121	0.99
9_L	20_L	1.116	0.99
47_V	83_T	1.108	0.99
77_T	156_L	1.105	0.99
184_G	192_R	1.098	0.99
31_R	36_R	1.091	0.99
24_F	40_I	1.089	0.99
7_I	27_L	1.088	0.99
176_L	232_V	1.085	0.99
109_S	132_L	1.068	0.99
52_M	57_L	1.065	0.98
12_V	15_D	1.053	0.98
233_D	252_M	1.051	0.98
85_N	101_G	1.048	0.98
245_A	248_N	1.046	0.98
214_M	217_K	1.041	0.98
167_A	223_D	1.027	0.98
89_L	101_G	1.023	0.98
179_L	235_A	1.020	0.98
6_I	174_A	1.018	0.98
170_A	225_A	1.012	0.98
57_L	75_I	1.000	0.98
4_P	39_V	0.998	0.98
87_T	91_W	0.993	0.98
203_Q	206_E	0.990	0.98
63_N	118_E	0.979	0.97
93_K	108_D	0.977	0.97
81_A	86_K	0.974	0.97
82_G	101_G	0.960	0.97
98_A	129_S	0.956	0.97
48_V	76_I	0.955	0.97
132_L	141_Y	0.943	0.97
112_V	159_V	0.941	0.97
30_Y	35_Q	0.939	0.97
30_Y	247_F	0.938	0.97
219_N	223_D	0.938	0.97
110_V	159_V	0.935	0.97
59_V	72_Q	0.930	0.96
71_D	74_D	0.926	0.96
73_I	121_H	0.926	0.96
251_P	255_R	0.915	0.96
213_G	217_K	0.912	0.96
49_D	53_K	0.908	0.96
130_P	171_T	0.905	0.96
51_L	54_G	0.903	0.96
116_D	119_L	0.898	0.96
24_F	91_W	0.890	0.95
183_S	239_H	0.887	0.95
166_T	170_A	0.886	0.95
65_L	119_L	0.882	0.95
4_P	137_L	0.872	0.95
107_G	141_Y	0.870	0.95
49_D	52_M	0.863	0.95
19_A	23_L	0.858	0.94
120_G	213_G	0.854	0.94
24_F	92_A	0.847	0.94
198_A	226_R	0.843	0.94
89_L	99_A	0.841	0.94
86_K	103_F	0.840	0.94
88_L	147_S	0.838	0.94
68_T	158_N	0.837	0.94
77_T	87_T	0.833	0.94
132_L	136_L	0.829	0.93
86_K	106_D	0.828	0.93
26_A	30_Y	0.828	0.93
252_M	255_R	0.826	0.93
12_V	47_V	0.820	0.93
57_L	69_P	0.819	0.93
204_L	209_I	0.817	0.93
109_S	133_I	0.817	0.93
28_V	142_L	0.813	0.93
20_L	91_W	0.810	0.93
6_I	168_L	0.809	0.93
39_V	137_L	0.808	0.92
160_N	213_G	0.807	0.92
125_A	149_G	0.806	0.92
111_K	126_Q	0.804	0.92
65_L	115_L	0.799	0.92
25_S	28_V	0.794	0.92
183_S	238_R	0.792	0.92
187_D	193_I	0.791	0.92
70_A	155_Q	0.787	0.91
245_A	255_R	0.787	0.91
9_L	14_L	0.786	0.91
128_G	168_L	0.780	0.91
53_K	56_N	0.779	0.91
162_D	217_K	0.775	0.91
112_V	125_A	0.775	0.91
196_M	204_L	0.775	0.91
5_L	246_L	0.774	0.91
75_I	79_A	0.765	0.90
27_L	142_L	0.763	0.90
34_H	37_P	0.760	0.90
166_T	220_A	0.758	0.90
149_G	157_M	0.751	0.89
161_A	217_K	0.750	0.89
85_N	146_S	0.750	0.89
160_N	216_V	0.748	0.89
28_V	95_H	0.746	0.89
149_G	164_A	0.743	0.89
185_I	222_L	0.739	0.89
12_V	181_D	0.736	0.88
10_G	42_H	0.735	0.88
167_A	171_T	0.734	0.88
201_A	218_V	0.733	0.88
57_L	72_Q	0.729	0.88
108_D	111_K	0.727	0.88
52_M	72_Q	0.726	0.88
20_L	88_L	0.724	0.88
115_L	119_L	0.723	0.88
8_K	162_D	0.716	0.87
122_V	160_N	0.714	0.87
129_S	132_L	0.713	0.87
188_G	207_Q	0.713	0.87
5_L	177_I	0.713	0.87
239_H	244_P	0.712	0.87
109_S	145_V	0.711	0.87
202_E	205_I	0.711	0.87
109_S	129_S	0.708	0.87
8_K	161_A	0.707	0.86
78_G	83_T	0.705	0.86
198_A	221_A	0.704	0.86
159_V	164_A	0.704	0.86
100_V	141_Y	0.703	0.86
199_A	203_Q	0.703	0.86
108_D	150_V	0.702	0.86
220_A	232_V	0.702	0.86
247_F	251_P	0.701	0.86
170_A	223_D	0.698	0.86
78_G	106_D	0.697	0.86
127_P	152_D	0.696	0.86
31_R	37_P	0.695	0.85
72_Q	75_I	0.694	0.85
78_G	104_L	0.692	0.85
35_Q	247_F	0.690	0.85
81_A	148_I	0.687	0.85
73_I	156_L	0.684	0.85
10_G	217_K	0.684	0.85
78_G	82_G	0.684	0.85
198_A	225_A	0.683	0.84
15_D	50_E	0.673	0.84
185_I	193_I	0.670	0.83
244_P	252_M	0.667	0.83
187_D	190_G	0.661	0.83
126_Q	152_D	0.660	0.82
223_D	227_T	0.659	0.82
128_G	164_A	0.658	0.82
103_F	106_D	0.656	0.82
45_G	64_G	0.655	0.82
31_R	97_I	0.653	0.82
176_L	224_A	0.647	0.81
211_T	218_V	0.643	0.81
197_T	201_A	0.643	0.81
133_I	137_L	0.642	0.81
222_L	226_R	0.641	0.81
88_L	191_Q	0.639	0.80
170_A	229_G	0.638	0.80
195_E	231_P	0.638	0.80
23_L	47_V	0.637	0.80
163_Q	219_N	0.637	0.80
233_D	245_A	0.636	0.80
82_G	106_D	0.635	0.80
113_T	152_D	0.635	0.80
83_T	87_T	0.630	0.79
31_R	149_G	0.630	0.79
223_D	226_R	0.630	0.79
81_A	146_S	0.629	0.79
19_A	22_R	0.628	0.79
107_G	132_L	0.627	0.79
213_G	216_V	0.627	0.79
7_I	40_I	0.624	0.79
8_K	217_K	0.622	0.79
110_V	149_G	0.619	0.78
135_S	140_G	0.617	0.78
127_P	171_T	0.616	0.78
64_G	216_V	0.614	0.78
24_F	47_V	0.612	0.77
180_S	214_M	0.610	0.77
160_N	217_K	0.609	0.77
104_L	144_V	0.608	0.77
9_L	13_L	0.604	0.77
119_L	122_V	0.600	0.76
16_S	238_R	0.593	0.75
5_L	30_Y	0.587	0.74
98_A	141_Y	0.587	0.74
168_L	171_T	0.585	0.74
193_I	204_L	0.585	0.74
65_L	124_L	0.584	0.74
39_V	133_I	0.584	0.74
196_M	256_I	0.584	0.74
27_L	37_P	0.583	0.74
27_L	40_I	0.582	0.74
77_T	81_A	0.581	0.74
45_G	122_V	0.580	0.74
224_A	229_G	0.580	0.74
93_K	98_A	0.578	0.73
91_W	94_K	0.577	0.73
10_G	214_M	0.574	0.73
11_G	43_G	0.574	0.73
177_I	233_D	0.573	0.73
57_L	76_I	0.571	0.72
47_V	50_E	0.570	0.72
10_G	161_A	0.569	0.72
31_R	142_L	0.567	0.72
26_A	245_A	0.566	0.72
68_T	73_I	0.563	0.71
210_I	214_M	0.560	0.71
45_G	162_D	0.558	0.71
222_L	225_A	0.555	0.70
45_G	160_N	0.552	0.70
163_Q	167_A	0.550	0.70
7_I	203_Q	0.550	0.70
9_L	12_V	0.547	0.69
10_G	158_N	0.546	0.69
64_G	213_G	0.546	0.69
153_E	157_M	0.545	0.69
55_L	71_D	0.545	0.69
68_T	213_G	0.545	0.69
10_G	162_D	0.545	0.69
186_L	190_G	0.544	0.69
163_Q	220_A	0.543	0.69
4_P	172_L	0.542	0.69
147_S	156_L	0.540	0.68
152_D	200_K	0.540	0.68
33_S	248_N	0.540	0.68
78_G	86_K	0.540	0.68
175_D	231_P	0.538	0.68
183_S	189_K	0.538	0.68
180_S	234_I	0.537	0.68
150_V	153_E	0.533	0.67
33_S	251_P	0.530	0.67
29_N	245_A	0.530	0.67
198_A	202_E	0.530	0.67
90_A	94_K	0.530	0.67
67_V	117_E	0.529	0.67
10_G	213_G	0.526	0.66
55_L	74_D	0.525	0.66
122_V	216_V	0.525	0.66
85_N	106_D	0.523	0.66
122_V	213_G	0.520	0.65
84_A	88_L	0.519	0.65
218_V	256_I	0.518	0.65
176_L	229_G	0.517	0.65
8_K	42_H	0.517	0.65
186_L	189_K	0.517	0.65
115_L	163_Q	0.516	0.65
94_K	152_D	0.514	0.65
81_A	90_A	0.514	0.65
120_G	160_N	0.512	0.64
211_T	215_I	0.510	0.64
165_A	176_L	0.510	0.64
9_L	23_L	0.510	0.64
218_V	227_T	0.510	0.64
89_L	144_V	0.509	0.64
91_W	138_E	0.509	0.64
47_V	51_L	0.509	0.64
13_L	23_L	0.508	0.64
130_P	168_L	0.508	0.64
65_L	120_G	0.508	0.64
67_V	119_L	0.506	0.63
241_E	245_A	0.505	0.63
72_Q	79_A	0.504	0.63
121_H	157_M	0.504	0.63
69_P	74_D	0.503	0.63
26_A	251_P	0.503	0.63
185_I	225_A	0.503	0.63
197_T	222_L	0.502	0.63
160_N	214_M	0.501	0.63
163_Q	166_T	0.500	0.62

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1gs5A	2	0.9961	100	0.294	Contact Map
2bufA	3	0.9961	100	0.3	Contact Map
2ap9A	3	0.9884	100	0.302	Contact Map
2v5hA	3	0.9961	100	0.306	Contact Map
2btyA	3	0.9922	100	0.311	Contact Map
2rd5A	3	0.9961	100	0.314	Contact Map
3l86A	1	0.9341	100	0.342	Contact Map
3wwnA	2	0.938	100	0.35	Contact Map
3s6kA	3	0.969	100	0.363	Contact Map
3d2mA	5	0.9612	100	0.364	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0086 seconds.