UVRA - ECOLI - GREMLIN Contacts

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UVRA - UvrABC system protein A

UniProt:	P0A698	Sequences: MDKIEVRGARTHNLKNINLVIPRDKLIVVTGLSGSGKSSLAFDTLYAEGQRRYVESLSAYARQFLSLMEKPDVDHIEGLSPAISIEQKSTSHNPRSTVGTITEIHDYLRLLFARVGEPRCPDHDVPLAAQTVSQMVDNVLSQPEGKRLMLLAPIIKERKGEHTKTLENLASQGYIRARIDGEVCDLSDPPKLELQKKHTIEVVVDRFKVRDDLTQRLAESFETALELSGGTAVVADMDDPKAEELLFSANFACPICGYSMRELEPRLFSFNNPAGACPTCDGLGVQQYFDPDRVIQNPELSLAGGAIRGWDRRNFYYFQMLKSLADHYKFDVEAPWGSLSANVHKVVLYGSGKENIEFKYMNDRGDTSIRRHPFEGVLHNMERRYKETESSAVREELAKFISNRPCASCEGTRLRREARHVYVENTPLPAISDMSIGHAMEFFNNLKLAGQRAKIAEKILKEIGDRLKFLVNVGLNYLTLSRSAETLSGGEAQRIRLASQIGAGLVGVMYVLDEPSIGLHQRDNERLLGTLIHLRDLGNTVIVVEHDEDAIRAADHVIDIGPGAGVHGGEVVAEGPLEAIMAVPESLTGQYMSGKRKIEVPKKRVPANPEKVLKLTGARGNNLKDVTLTLPVGLFTCITGVSGSGKSTLINDTLFPIAQRQLNGATIAEPAPYRDIQGLEHFDKVIDIDQSPIGRTPRSNPATYTGVFTPVRELFAGVPESRARGYTPGRFSFNVRGGRCEACQGDGVIKVEMHFLPDIYVPCDQCKGKRYNRETLEIKYKGKTIHEVLDMTIEEAREFFDAVPALARKLQTLMDVGLTYIRLGQSATTLSGGEAQRVKLARELSKRGTGQTLYILDEPTTGLHFADIQQLLDVLHKLRDQGNTIVVIEHNLDVIKTADWIVDLGPEGGSGGGEILVSGTPETVAECEASHTARFLKPML	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG11061
Length:	940 (929)
Sequences:	3328 (1521)
Seq/√Len:	49.9

ECOLI - UVRA
BACSU - UVRA
HALSA - Q9HMA2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
21_I	27_I	5.610	1.00
619_R	674_R	4.945	1.00
590_Q	595_K	4.868	1.00
614_K	629_T	4.838	1.00
10_R	74_D	4.517	1.00
279_T	408_S	4.286	1.00
590_Q	596_R	4.210	1.00
166_L	179_I	4.189	1.00
794_E	814_M	4.185	1.00
267_L	418_A	3.764	1.00
635_F	887_V	3.664	1.00
784_T	787_E	3.635	1.00
3_K	20_V	3.626	1.00
525_E	935_F	3.588	1.00
7_R	20_V	3.584	1.00
340_S	343_V	3.535	1.00
336_W	344_H	3.496	1.00
21_I	558_I	3.496	1.00
560_I	571_V	3.486	1.00
917_V	927_C	3.479	1.00
866_A	869_Q	3.472	1.00
556_H	574_E	3.465	1.00
931_H	934_R	3.464	1.00
630_L	650_I	3.463	1.00
630_L	886_V	3.310	1.00
433_D	481_S	3.264	1.00
570_E	585_E	3.261	1.00
551_I	557_V	3.251	1.00
630_L	636_T	3.209	1.00
119_R	422_Y	3.122	1.00
811_Q	815_D	3.108	1.00
628_L	915_I	3.036	1.00
614_K	677_Q	3.033	1.00
105_H	432_S	2.963	1.00
548_E	552_R	2.958	1.00
297_N	300_L	2.951	1.00
904_L	915_I	2.947	1.00
612_V	629_T	2.923	1.00
19_L	558_I	2.896	1.00
917_V	924_V	2.878	1.00
604_R	922_E	2.851	1.00
341_A	345_K	2.830	1.00
117_E	452_R	2.827	1.00
637_C	898_A	2.820	1.00
576_P	579_A	2.805	1.00
6_V	19_L	2.800	1.00
567_H	794_E	2.789	1.00
125_V	255_I	2.776	1.00
522_R	907_E	2.773	1.00
303_A	333_E	2.765	1.00
449_A	452_R	2.754	1.00
662_L	665_A	2.741	1.00
786_H	790_D	2.714	1.00
5_E	20_V	2.708	1.00
27_I	540_T	2.655	1.00
152_A	228_S	2.644	1.00
853_L	886_V	2.634	1.00
299_E	337_G	2.621	1.00
221_F	232_A	2.600	1.00
615_L	630_L	2.581	1.00
573_A	580_I	2.580	1.00
566_V	822_R	2.552	1.00
525_E	549_D	2.537	1.00
120_C	123_H	2.536	1.00
557_V	577_L	2.517	1.00
178_R	201_E	2.512	1.00
438_H	910_S	2.497	1.00
325_A	330_F	2.475	1.00
798_E	801_D	2.468	1.00
45_L	542_I	2.462	1.00
557_V	580_I	2.451	1.00
783_K	791_M	2.441	1.00
29_V	558_I	2.410	1.00
718_V	721_S	2.401	1.00
632_V	682_F	2.373	1.00
616_T	675_D	2.334	1.00
616_T	627_T	2.315	1.00
202_V	227_L	2.302	1.00
573_A	583_V	2.282	1.00
608_N	634_L	2.279	1.00
120_C	256_C	2.277	1.00
658_A	853_L	2.257	1.00
577_L	581_M	2.238	1.00
614_K	627_T	2.212	1.00
6_V	9_A	2.164	1.00
779_K	784_T	2.156	1.00
431_I	439_A	2.151	1.00
468_K	472_N	2.146	1.00
289_F	397_L	2.141	1.00
123_H	256_C	2.140	1.00
807_A	811_Q	2.140	1.00
616_T	677_Q	2.137	1.00
177_A	184_C	2.127	1.00
624_K	914_E	2.123	1.00
914_E	929_A	2.117	1.00
532_I	535_R	2.115	1.00
797_R	811_Q	2.098	1.00
620_G	671_A	2.091	1.00
330_F	343_V	2.087	1.00
620_G	672_P	2.084	1.00
525_E	529_G	2.062	1.00
715_F	788_V	2.057	1.00
791_M	799_F	2.051	1.00
596_R	869_Q	2.049	1.00
652_D	656_P	2.047	1.00
682_F	853_L	2.046	1.00
900_W	923_T	2.036	1.00
638_I	650_I	2.032	1.00
122_D	256_C	2.009	1.00
121_P	260_M	1.996	1.00
150_L	234_V	1.995	1.00
143_P	146_K	1.993	1.00
169_L	202_V	1.988	1.00
431_I	443_F	1.981	1.00
783_K	799_F	1.977	0.99
292_D	298_P	1.969	0.99
412_T	429_P	1.957	0.99
139_V	221_F	1.951	0.99
615_L	673_Y	1.936	0.99
589_G	593_S	1.915	0.99
178_R	235_A	1.915	0.99
437_G	476_N	1.914	0.99
620_G	653_T	1.912	0.99
408_S	416_R	1.906	0.99
619_R	672_P	1.899	0.99
663_N	666_T	1.887	0.99
375_E	383_R	1.882	0.99
797_R	814_M	1.881	0.99
794_E	819_T	1.880	0.99
657_I	673_Y	1.879	0.99
10_R	72_D	1.876	0.99
178_R	244_E	1.867	0.99
148_L	207_F	1.866	0.99
707_V	806_L	1.864	0.99
790_D	822_R	1.862	0.99
156_K	231_T	1.858	0.99
444_N	464_G	1.858	0.99
341_A	344_H	1.844	0.99
815_D	877_K	1.842	0.99
349_Y	378_L	1.830	0.99
573_A	579_A	1.826	0.99
875_L	887_V	1.826	0.99
615_L	650_I	1.822	0.99
120_C	253_C	1.810	0.99
606_P	609_P	1.810	0.99
193_E	196_K	1.807	0.99
295_I	336_W	1.801	0.99
302_L	332_V	1.796	0.99
552_R	581_M	1.783	0.99
615_L	618_A	1.783	0.99
135_M	221_F	1.782	0.99
166_L	177_A	1.775	0.99
615_L	653_T	1.767	0.99
412_T	427_P	1.758	0.99
476_N	911_G	1.757	0.99
636_T	884_T	1.754	0.99
288_Y	382_E	1.748	0.99
596_R	866_A	1.739	0.99
139_V	209_V	1.739	0.99
19_L	27_I	1.722	0.99
174_Y	204_V	1.719	0.99
157_E	274_A	1.715	0.99
796_A	823_L	1.701	0.98
108_L	112_F	1.700	0.98
869_Q	873_D	1.698	0.98
628_L	902_V	1.697	0.98
629_T	918_S	1.697	0.98
15_K	570_E	1.696	0.98
742_A	765_Q	1.695	0.98
289_F	294_V	1.694	0.98
117_E	126_P	1.679	0.98
235_A	244_E	1.676	0.98
606_P	610_E	1.672	0.98
673_Y	676_I	1.671	0.98
123_H	258_Y	1.669	0.98
151_L	203_V	1.662	0.98
17_I	29_V	1.655	0.98
177_A	186_L	1.650	0.98
334_A	338_S	1.643	0.98
233_V	244_E	1.637	0.98
630_L	638_I	1.634	0.98
324_L	330_F	1.629	0.98
608_N	611_K	1.627	0.98
306_A	336_W	1.617	0.98
201_E	233_V	1.615	0.98
900_W	918_S	1.608	0.98
708_F	785_I	1.606	0.98
115_V	448_L	1.603	0.98
706_G	709_T	1.599	0.98
23_R	506_V	1.596	0.98
207_F	217_L	1.580	0.97
552_R	577_L	1.580	0.97
658_A	679_L	1.580	0.97
140_L	214_T	1.573	0.97
657_I	676_I	1.560	0.97
412_T	430_A	1.556	0.97
683_D	849_T	1.554	0.97
17_I	571_V	1.554	0.97
336_W	347_V	1.553	0.97
110_L	459_I	1.552	0.97
876_H	897_T	1.548	0.97
506_V	511_V	1.544	0.97
579_A	583_V	1.540	0.97
578_E	584_P	1.534	0.97
381_M	397_L	1.532	0.97
655_F	659_Q	1.529	0.97
624_K	910_S	1.517	0.97
811_Q	814_M	1.517	0.97
347_V	377_V	1.510	0.97
139_V	234_V	1.510	0.97
335_P	338_S	1.509	0.97
441_E	445_N	1.507	0.97
549_D	552_R	1.507	0.97
298_P	344_H	1.503	0.97
427_P	430_A	1.498	0.97
626_V	915_I	1.498	0.97
412_T	419_R	1.492	0.96
123_H	253_C	1.491	0.96
142_Q	146_K	1.489	0.96
17_I	560_I	1.487	0.96
608_N	612_V	1.487	0.96
150_L	224_A	1.485	0.96
426_T	434_M	1.480	0.96
615_L	676_I	1.477	0.96
180_D	198_H	1.476	0.96
787_E	790_D	1.472	0.96
426_T	430_A	1.470	0.96
440_M	471_V	1.470	0.96
709_T	713_E	1.465	0.96
578_E	582_A	1.464	0.96
915_I	918_S	1.460	0.96
263_L	421_V	1.455	0.96
135_M	225_L	1.447	0.96
879_R	885_I	1.445	0.96
213_L	217_L	1.440	0.96
169_L	186_L	1.437	0.96
609_P	634_L	1.431	0.95
716_A	728_P	1.428	0.95
611_K	681_H	1.426	0.95
659_Q	665_A	1.423	0.95
174_Y	227_L	1.420	0.95
158_R	162_H	1.420	0.95
27_I	558_I	1.419	0.95
148_L	209_V	1.409	0.95
294_V	309_G	1.405	0.95
584_P	595_K	1.401	0.95
525_E	934_R	1.400	0.95
793_I	821_I	1.400	0.95
330_F	334_A	1.385	0.95
573_A	581_M	1.382	0.95
907_E	931_H	1.380	0.94
662_L	670_P	1.374	0.94
253_C	256_C	1.372	0.94
674_R	677_Q	1.366	0.94
930_S	933_A	1.365	0.94
157_E	199_T	1.364	0.94
324_L	343_V	1.362	0.94
708_F	771_Y	1.360	0.94
331_D	334_A	1.355	0.94
620_G	648_T	1.350	0.94
155_I	162_H	1.342	0.94
532_I	553_A	1.342	0.94
174_Y	223_T	1.338	0.93
443_F	463_I	1.336	0.93
435_S	438_H	1.327	0.93
124_D	422_Y	1.319	0.93
598_I	896_K	1.313	0.93
168_N	172_Q	1.312	0.93
656_P	670_P	1.311	0.93
112_F	431_I	1.309	0.93
779_K	787_E	1.305	0.93
668_A	671_A	1.301	0.93
655_F	685_V	1.299	0.92
154_I	165_T	1.292	0.92
750_K	760_Y	1.284	0.92
16_N	74_D	1.283	0.92
419_R	427_P	1.282	0.92
135_M	247_F	1.275	0.92
860_T	894_V	1.268	0.92
116_G	421_V	1.267	0.91
422_Y	427_P	1.267	0.91
176_R	206_R	1.267	0.91
184_C	190_P	1.266	0.91
328_Y	346_V	1.265	0.91
345_K	349_Y	1.258	0.91
325_A	332_V	1.255	0.91
710_P	713_E	1.255	0.91
146_K	236_D	1.253	0.91
170_A	187_S	1.251	0.91
295_I	306_A	1.249	0.91
279_T	407_A	1.245	0.91
632_V	636_T	1.244	0.91
150_L	217_L	1.238	0.91
331_D	343_V	1.233	0.90
660_R	670_P	1.231	0.90
440_M	444_N	1.229	0.90
578_E	581_M	1.228	0.90
136_V	221_F	1.220	0.90
27_I	542_I	1.220	0.90
112_F	430_A	1.219	0.90
601_P	604_R	1.219	0.90
591_Y	596_R	1.218	0.90
279_T	286_Q	1.214	0.90
662_L	666_T	1.213	0.90
112_F	427_P	1.207	0.89
730_R	775_T	1.203	0.89
357_E	371_R	1.197	0.89
295_I	344_H	1.194	0.89
148_L	234_V	1.192	0.89
138_N	141_S	1.191	0.89
619_R	625_D	1.191	0.89
6_V	542_I	1.190	0.89
662_L	671_A	1.185	0.88
236_D	245_L	1.183	0.88
872_L	897_T	1.181	0.88
780_Y	803_V	1.181	0.88
133_S	137_D	1.179	0.88
30_T	551_I	1.175	0.88
229_G	250_N	1.175	0.88
359_K	369_I	1.175	0.88
19_L	29_V	1.174	0.88
321_L	347_V	1.171	0.88
685_V	855_I	1.170	0.88
440_M	464_G	1.169	0.88
137_D	773_R	1.169	0.88
579_A	582_A	1.169	0.88
419_R	429_P	1.168	0.88
907_E	911_G	1.167	0.88
295_I	348_L	1.164	0.88
415_R	418_A	1.161	0.87
453_A	457_E	1.161	0.87
142_Q	245_L	1.161	0.87
450_G	453_A	1.160	0.87
7_R	75_H	1.154	0.87
650_I	654_L	1.152	0.87
167_E	170_A	1.151	0.87
927_C	933_A	1.150	0.87
549_D	553_A	1.150	0.87
412_T	433_D	1.148	0.87
639_T	903_D	1.148	0.87
301_S	335_P	1.145	0.87
139_V	232_A	1.144	0.87
639_T	895_I	1.142	0.87
296_Q	308_R	1.142	0.87
303_A	332_V	1.141	0.87
600_V	604_R	1.141	0.87
614_K	675_D	1.139	0.86
710_P	805_A	1.138	0.86
626_V	904_L	1.137	0.86
155_I	158_R	1.135	0.86
249_A	736_R	1.133	0.86
670_P	673_Y	1.130	0.86
7_R	18_N	1.130	0.86
769_K	790_D	1.130	0.86
440_M	468_K	1.128	0.86
607_A	610_E	1.126	0.86
26_L	535_R	1.125	0.86
162_H	165_T	1.125	0.86
875_L	885_I	1.124	0.86
300_L	304_G	1.122	0.86
655_F	855_I	1.121	0.86
289_F	381_M	1.119	0.85
149_M	235_A	1.119	0.85
927_C	930_S	1.116	0.85
380_N	397_L	1.113	0.85
587_L	591_Y	1.109	0.85
673_Y	678_G	1.107	0.85
670_P	678_G	1.107	0.85
142_Q	236_D	1.104	0.85
321_L	332_V	1.102	0.85
528_L	550_A	1.100	0.84
29_V	41_A	1.100	0.84
720_E	723_A	1.099	0.84
334_A	343_V	1.096	0.84
657_I	661_Q	1.096	0.84
625_D	674_R	1.095	0.84
294_V	377_V	1.095	0.84
600_V	896_K	1.094	0.84
357_E	369_I	1.093	0.84
769_K	787_E	1.090	0.84
635_F	875_L	1.090	0.84
529_G	532_I	1.088	0.84
382_E	386_K	1.086	0.84
574_E	580_I	1.081	0.83
856_L	875_L	1.080	0.83
45_L	509_M	1.080	0.83
132_V	221_F	1.078	0.83
472_N	529_G	1.078	0.83
920_T	923_T	1.077	0.83
793_I	814_M	1.076	0.83
338_S	342_N	1.075	0.83
610_E	634_L	1.074	0.83
850_G	883_N	1.073	0.83
298_P	336_W	1.069	0.83
290_D	402_S	1.069	0.83
26_L	541_V	1.067	0.83
709_T	728_P	1.066	0.83
29_V	560_I	1.065	0.82
504_G	533_H	1.065	0.82
429_P	433_D	1.064	0.82
45_L	511_V	1.064	0.82
613_L	682_F	1.063	0.82
437_G	910_S	1.062	0.82
327_H	356_I	1.062	0.82
617_G	625_D	1.060	0.82
573_A	576_P	1.056	0.82
916_L	933_A	1.056	0.82
591_Y	866_A	1.054	0.82
876_H	880_D	1.053	0.82
162_H	195_Q	1.051	0.82
21_I	540_T	1.050	0.82
19_L	571_V	1.050	0.82
521_Q	524_N	1.049	0.81
797_R	807_A	1.048	0.81
131_T	742_A	1.044	0.81
238_D	242_A	1.039	0.81
925_A	933_A	1.036	0.81
654_L	657_I	1.032	0.80
338_S	341_A	1.032	0.80
343_V	346_V	1.030	0.80
272_N	418_A	1.030	0.80
724_R	777_E	1.029	0.80
901_I	924_V	1.026	0.80
528_L	532_I	1.025	0.80
676_I	679_L	1.024	0.80
163_T	191_K	1.023	0.80
683_D	851_Q	1.023	0.80
24_D	506_V	1.023	0.80
599_E	869_Q	1.023	0.80
438_H	441_E	1.022	0.80
8_G	16_N	1.022	0.80
154_I	202_V	1.021	0.80
615_L	656_P	1.020	0.80
426_T	431_I	1.020	0.80
471_V	476_N	1.019	0.80
439_A	467_L	1.018	0.79
398_A	401_I	1.018	0.79
580_I	589_G	1.017	0.79
814_M	819_T	1.017	0.79
638_I	884_T	1.012	0.79
656_P	668_A	1.011	0.79
383_R	387_E	1.007	0.79
454_K	457_E	1.006	0.79
648_T	653_T	1.005	0.79
714_L	806_L	1.003	0.78
656_P	671_A	1.000	0.78
264_E	767_K	0.994	0.78
125_V	258_Y	0.992	0.78
4_I	45_L	0.985	0.77
653_T	656_P	0.985	0.77
705_T	842_R	0.982	0.77
380_N	384_R	0.978	0.77
133_S	218_A	0.977	0.77
205_D	216_R	0.975	0.76
123_H	255_I	0.975	0.76
601_P	896_K	0.975	0.76
630_L	853_L	0.972	0.76
730_R	772_N	0.972	0.76
635_F	872_L	0.970	0.76
437_G	471_V	0.967	0.76
161_E	191_K	0.966	0.76
375_E	380_N	0.966	0.76
29_V	541_V	0.965	0.76
877_K	881_Q	0.964	0.76
424_E	447_K	0.962	0.75
328_Y	351_S	0.961	0.75
658_A	665_A	0.961	0.75
336_W	348_L	0.958	0.75
17_I	558_I	0.954	0.75
178_R	183_V	0.953	0.75
658_A	685_V	0.951	0.75
607_A	634_L	0.950	0.75
138_N	247_F	0.948	0.74
534_L	845_S	0.947	0.74
355_N	371_R	0.947	0.74
772_N	775_T	0.945	0.74
119_R	123_H	0.942	0.74
160_G	198_H	0.942	0.74
671_A	678_G	0.941	0.74
397_L	401_I	0.941	0.74
926_E	937_K	0.940	0.74
393_V	397_L	0.939	0.74
298_P	337_G	0.939	0.74
917_V	923_T	0.938	0.74
709_T	718_V	0.938	0.74
23_R	511_V	0.934	0.73
663_N	670_P	0.933	0.73
632_V	884_T	0.933	0.73
617_G	627_T	0.933	0.73
637_C	887_V	0.932	0.73
217_L	221_F	0.929	0.73
122_D	258_Y	0.927	0.73
653_T	673_Y	0.919	0.72
251_F	263_L	0.917	0.72
301_S	305_G	0.916	0.72
613_L	658_A	0.916	0.72
339_L	344_H	0.915	0.72
132_V	225_L	0.915	0.72
577_L	580_I	0.914	0.72
228_S	231_T	0.913	0.72
162_H	180_D	0.913	0.72
125_V	254_P	0.911	0.71
809_K	845_S	0.910	0.71
286_Q	407_A	0.909	0.71
658_A	662_L	0.908	0.71
101_I	484_A	0.907	0.71
92_H	484_A	0.907	0.71
660_R	665_A	0.906	0.71
654_L	658_A	0.906	0.71
617_G	673_Y	0.905	0.71
617_G	674_R	0.903	0.71
872_L	894_V	0.900	0.70
29_V	542_I	0.898	0.70
334_A	340_S	0.898	0.70
726_Y	775_T	0.896	0.70
876_H	879_R	0.892	0.70
601_P	922_E	0.891	0.70
308_R	400_F	0.890	0.70
437_G	911_G	0.888	0.69
336_W	339_L	0.884	0.69
303_A	322_K	0.884	0.69
917_V	925_A	0.884	0.69
177_A	189_P	0.883	0.69
648_T	652_D	0.883	0.69
339_L	343_V	0.881	0.69
566_V	795_E	0.881	0.69
895_I	901_I	0.881	0.69
737_G	741_E	0.878	0.69
566_V	794_E	0.874	0.68
615_L	654_L	0.874	0.68
658_A	682_F	0.873	0.68
150_L	232_A	0.872	0.68
56_S	507_G	0.871	0.68
567_H	792_T	0.871	0.68
636_T	879_R	0.871	0.68
88_K	99_G	0.870	0.68
590_Q	593_S	0.869	0.68
573_A	586_S	0.869	0.68
422_Y	430_A	0.867	0.68
657_I	660_R	0.866	0.68
664_G	670_P	0.866	0.68
278_P	417_E	0.865	0.67
233_V	246_L	0.864	0.67
278_P	415_R	0.863	0.67
439_A	443_F	0.863	0.67
600_V	939_M	0.863	0.67
522_R	931_H	0.863	0.67
634_L	900_W	0.861	0.67
525_E	552_R	0.860	0.67
309_G	400_F	0.860	0.67
416_R	420_H	0.859	0.67
6_V	45_L	0.859	0.67
868_I	872_L	0.858	0.67
653_T	671_A	0.856	0.67
287_Q	401_I	0.855	0.67
194_L	197_K	0.854	0.66
295_I	298_P	0.853	0.66
430_A	433_D	0.853	0.66
726_Y	774_E	0.853	0.66
6_V	73_V	0.851	0.66
119_R	125_V	0.848	0.66
585_E	590_Q	0.847	0.66
172_Q	227_L	0.844	0.66
648_T	656_P	0.844	0.66
533_H	537_L	0.843	0.65
532_I	536_D	0.843	0.65
902_V	915_I	0.841	0.65
653_T	672_P	0.840	0.65
637_C	901_I	0.840	0.65
155_I	159_K	0.840	0.65
162_H	194_L	0.839	0.65
801_D	807_A	0.838	0.65
866_A	870_Q	0.838	0.65
256_C	259_S	0.837	0.65
169_L	172_Q	0.837	0.65
658_A	661_Q	0.835	0.65
316_Y	320_M	0.835	0.65
385_Y	401_I	0.835	0.65
630_L	654_L	0.834	0.65
289_F	378_L	0.834	0.65
82_A	509_M	0.831	0.64
294_V	378_L	0.831	0.64
244_E	263_L	0.830	0.64
934_R	938_P	0.829	0.64
135_M	232_A	0.828	0.64
583_V	586_S	0.827	0.64
122_D	255_I	0.827	0.64
441_E	444_N	0.826	0.64
656_P	661_Q	0.824	0.64
322_K	326_D	0.824	0.64
556_H	576_P	0.824	0.64
231_T	246_L	0.823	0.64
853_L	884_T	0.823	0.64
609_P	632_V	0.822	0.63
164_K	688_I	0.821	0.63
136_V	218_A	0.821	0.63
516_S	550_A	0.819	0.63
150_L	207_F	0.818	0.63
923_T	926_E	0.817	0.63
710_P	809_K	0.816	0.63
309_G	377_V	0.816	0.63
924_V	933_A	0.816	0.63
225_L	249_A	0.815	0.63
119_R	126_P	0.814	0.63
579_A	585_E	0.814	0.63
321_L	374_F	0.813	0.63
557_V	581_M	0.813	0.63
929_A	934_R	0.813	0.63
351_S	373_P	0.812	0.62
9_A	73_V	0.812	0.62
325_A	329_K	0.811	0.62
584_P	589_G	0.810	0.62
600_V	922_E	0.810	0.62
26_L	543_V	0.809	0.62
872_L	887_V	0.806	0.62
551_I	592_M	0.806	0.62
217_L	220_S	0.804	0.62
615_L	657_I	0.804	0.62
179_I	189_P	0.804	0.62
795_E	798_E	0.801	0.61
346_V	351_S	0.800	0.61
914_E	918_S	0.798	0.61
598_I	601_P	0.798	0.61
720_E	726_Y	0.798	0.61
618_A	653_T	0.796	0.61
288_Y	404_R	0.793	0.61
328_Y	356_I	0.793	0.61
928_E	934_R	0.793	0.61
779_K	782_G	0.790	0.60
384_R	387_E	0.788	0.60
713_E	728_P	0.788	0.60
115_V	452_R	0.787	0.60
165_T	169_L	0.786	0.60
754_H	757_P	0.786	0.60
115_V	423_V	0.785	0.60
842_R	845_S	0.785	0.60
576_P	581_M	0.784	0.60
220_S	223_T	0.783	0.60
811_Q	877_K	0.780	0.59
499_S	504_G	0.780	0.59
385_Y	398_A	0.780	0.59
11_T	69_E	0.779	0.59
648_T	904_L	0.779	0.59
656_P	660_R	0.777	0.59
573_A	584_P	0.777	0.59
121_P	258_Y	0.776	0.59
368_S	372_H	0.776	0.59
901_I	904_L	0.775	0.59
378_L	381_M	0.775	0.59
343_V	347_V	0.775	0.59
572_V	587_L	0.775	0.59
448_L	460_L	0.774	0.59
306_A	321_L	0.774	0.59
843_E	854_Y	0.774	0.59
436_I	471_V	0.773	0.59
583_V	590_Q	0.772	0.59
162_H	200_I	0.772	0.59
416_R	419_R	0.772	0.59
579_A	584_P	0.772	0.59
331_D	340_S	0.771	0.58
119_R	420_H	0.771	0.58
626_V	916_L	0.771	0.58
460_L	464_G	0.768	0.58
761_V	874_V	0.767	0.58
351_S	356_I	0.767	0.58
849_T	852_T	0.767	0.58
548_E	939_M	0.767	0.58
396_E	400_F	0.766	0.58
504_G	534_L	0.764	0.58
604_R	896_K	0.764	0.58
324_L	346_V	0.764	0.58
656_P	659_Q	0.763	0.58
620_G	673_Y	0.762	0.58
659_Q	663_N	0.762	0.58
447_K	453_A	0.762	0.58
525_E	553_A	0.761	0.57
149_M	183_V	0.759	0.57
8_G	74_D	0.759	0.57
650_I	653_T	0.757	0.57
159_K	198_H	0.757	0.57
663_N	682_F	0.754	0.57
326_D	329_K	0.754	0.57
184_C	189_P	0.754	0.57
726_Y	730_R	0.754	0.57
707_V	710_P	0.754	0.57
237_M	242_A	0.754	0.57
185_D	188_D	0.754	0.57
587_L	596_R	0.753	0.57
665_A	670_P	0.753	0.57
635_F	884_T	0.753	0.57
301_S	304_G	0.753	0.57
365_G	368_S	0.752	0.57
405_P	410_E	0.751	0.56
587_L	866_A	0.750	0.56
613_L	853_L	0.750	0.56
479_T	884_T	0.747	0.56
144_E	210_R	0.747	0.56
665_A	721_S	0.747	0.56
398_A	751_V	0.746	0.56
465_D	504_G	0.746	0.56
17_I	295_I	0.744	0.56
803_V	807_A	0.744	0.56
630_L	884_T	0.744	0.56
571_V	574_E	0.744	0.56
127_L	258_Y	0.743	0.56
123_H	127_L	0.743	0.56
661_Q	670_P	0.743	0.56
119_R	416_R	0.741	0.55
827_A	838_V	0.741	0.55
599_E	602_K	0.739	0.55
663_N	846_K	0.738	0.55
927_C	934_R	0.737	0.55
665_A	671_A	0.737	0.55
573_A	648_T	0.737	0.55
626_V	653_T	0.736	0.55
257_G	260_M	0.735	0.55
472_N	533_H	0.734	0.55
660_R	663_N	0.734	0.55
925_A	939_M	0.731	0.54
613_L	632_V	0.731	0.54
327_H	351_S	0.731	0.54
452_R	455_I	0.730	0.54
306_A	344_H	0.729	0.54
783_K	795_E	0.729	0.54
39_S	651_N	0.728	0.54
590_Q	866_A	0.727	0.54
788_V	791_M	0.727	0.54
429_P	432_S	0.727	0.54
126_P	422_Y	0.726	0.54
11_T	72_D	0.726	0.54
324_L	328_Y	0.725	0.54
301_S	333_E	0.724	0.54
716_A	727_T	0.724	0.54
395_E	398_A	0.723	0.54
355_N	373_P	0.723	0.54
45_L	558_I	0.722	0.54
613_L	630_L	0.722	0.54
552_R	556_H	0.722	0.54
650_I	855_I	0.721	0.53
145_G	150_L	0.720	0.53
208_K	219_E	0.719	0.53
317_Y	320_M	0.717	0.53
655_F	658_A	0.715	0.53
720_E	724_R	0.715	0.53
426_T	438_H	0.714	0.53
742_A	749_I	0.714	0.53
179_I	200_I	0.714	0.53
149_M	237_M	0.713	0.53
865_F	872_L	0.713	0.53
549_D	877_K	0.712	0.53
426_T	442_F	0.712	0.53
838_V	841_A	0.712	0.53
655_F	687_D	0.711	0.52
628_L	916_L	0.710	0.52
650_I	656_P	0.710	0.52
627_T	677_Q	0.709	0.52
450_G	454_K	0.708	0.52
896_K	936_L	0.706	0.52
425_N	430_A	0.706	0.52
748_V	762_P	0.706	0.52
159_K	162_H	0.704	0.52
117_E	868_I	0.703	0.52
5_E	77_E	0.703	0.52
358_F	394_R	0.702	0.51
132_V	135_M	0.702	0.51
686_I	880_D	0.701	0.51
287_Q	398_A	0.701	0.51
598_I	897_T	0.701	0.51
461_K	465_D	0.701	0.51
607_A	611_K	0.700	0.51
192_L	198_H	0.700	0.51
722_R	778_I	0.699	0.51
828_T	854_Y	0.699	0.51
616_T	674_R	0.699	0.51
156_K	199_T	0.699	0.51
138_N	245_L	0.698	0.51
407_A	410_E	0.697	0.51
161_E	195_Q	0.697	0.51
119_R	425_N	0.697	0.51
99_G	439_A	0.696	0.51
224_A	232_A	0.696	0.51
797_R	815_D	0.695	0.51
719_P	723_A	0.694	0.51
581_M	589_G	0.694	0.51
304_G	333_E	0.693	0.51
212_D	217_L	0.693	0.51
53_Y	290_D	0.689	0.50
609_P	612_V	0.689	0.50
155_I	160_G	0.689	0.50
630_L	682_F	0.688	0.50
316_Y	319_Q	0.688	0.50
323_S	327_H	0.687	0.50
720_E	778_I	0.687	0.50
602_K	926_E	0.687	0.50
122_D	125_V	0.687	0.50
920_T	924_V	0.685	0.50
118_P	421_V	0.685	0.50
710_P	778_I	0.683	0.50
258_Y	422_Y	0.682	0.49
200_I	688_I	0.682	0.49
235_A	238_D	0.682	0.49
314_N	318_F	0.681	0.49
787_E	916_L	0.680	0.49
29_V	187_S	0.680	0.49
115_V	449_A	0.680	0.49
551_I	577_L	0.677	0.49
204_V	448_L	0.677	0.49
256_C	442_F	0.675	0.49
178_R	233_V	0.675	0.49
303_A	334_A	0.674	0.49
390_S	394_R	0.673	0.49
25_K	46_Y	0.672	0.48
145_G	208_K	0.671	0.48
636_T	886_V	0.670	0.48
353_K	373_P	0.670	0.48
74_D	186_L	0.670	0.48
342_N	345_K	0.670	0.48
89_S	855_I	0.669	0.48
653_T	657_I	0.668	0.48
660_R	668_A	0.668	0.48
842_R	846_K	0.668	0.48
327_H	358_F	0.668	0.48
660_R	669_E	0.667	0.48
151_L	201_E	0.667	0.48
310_W	321_L	0.667	0.48
657_I	671_A	0.667	0.48
325_A	331_D	0.666	0.48
135_M	855_I	0.665	0.48
236_D	242_A	0.665	0.48
184_C	188_D	0.664	0.48
552_R	578_E	0.663	0.48
872_L	876_H	0.663	0.48
66_S	560_I	0.663	0.48
606_P	879_R	0.663	0.48
291_P	349_Y	0.663	0.48
183_V	201_E	0.662	0.47
179_I	192_L	0.661	0.47
130_Q	252_A	0.661	0.47
848_G	881_Q	0.661	0.47
796_A	810_L	0.660	0.47
322_K	332_V	0.659	0.47
25_K	600_V	0.659	0.47
89_S	492_A	0.658	0.47
808_R	848_G	0.658	0.47
609_P	681_H	0.657	0.47
449_A	453_A	0.656	0.47
112_F	263_L	0.656	0.47
797_R	801_D	0.655	0.47
465_D	533_H	0.654	0.47
658_A	671_A	0.654	0.47
613_L	628_L	0.653	0.46
638_I	902_V	0.652	0.46
162_H	198_H	0.652	0.46
819_T	870_Q	0.651	0.46
92_H	485_E	0.651	0.46
724_R	774_E	0.650	0.46
444_N	468_K	0.650	0.46
10_R	16_N	0.650	0.46
598_I	872_L	0.650	0.46
629_T	677_Q	0.649	0.46
456_A	721_S	0.648	0.46
541_V	653_T	0.648	0.46
281_D	310_W	0.648	0.46
56_S	70_K	0.647	0.46
746_D	749_I	0.646	0.46
359_K	367_T	0.644	0.46
132_V	218_A	0.644	0.46
608_N	681_H	0.644	0.46
123_H	133_S	0.644	0.46
594_G	597_K	0.644	0.46
917_V	926_E	0.644	0.46
325_A	343_V	0.644	0.46
710_P	806_L	0.643	0.45
29_V	83_I	0.643	0.45
458_K	506_V	0.643	0.45
59_A	63_Q	0.642	0.45
309_G	317_Y	0.642	0.45
582_A	585_E	0.641	0.45
307_I	310_W	0.641	0.45
435_S	439_A	0.641	0.45
442_F	559_D	0.640	0.45
865_F	883_N	0.640	0.45
583_V	589_G	0.640	0.45
318_F	321_L	0.640	0.45
145_G	210_R	0.639	0.45
773_R	777_E	0.639	0.45
125_V	256_C	0.638	0.45
726_Y	777_E	0.638	0.45
274_A	381_M	0.638	0.45
388_T	393_V	0.638	0.45
127_L	252_A	0.637	0.45
424_E	442_F	0.637	0.45
289_F	560_I	0.637	0.45
45_L	541_V	0.637	0.45
293_R	296_Q	0.637	0.45
412_T	771_Y	0.636	0.45
661_Q	679_L	0.634	0.45
660_R	671_A	0.634	0.45
330_F	346_V	0.634	0.45
657_I	665_A	0.634	0.45
612_V	900_W	0.633	0.44
89_S	865_F	0.632	0.44
529_G	533_H	0.632	0.44
558_I	574_E	0.632	0.44
522_R	526_R	0.632	0.44
12_H	829_T	0.630	0.44
165_T	202_V	0.630	0.44
718_V	780_Y	0.629	0.44
23_R	80_S	0.629	0.44
213_L	220_S	0.628	0.44
174_Y	226_E	0.628	0.44
29_V	571_V	0.628	0.44
626_V	676_I	0.628	0.44
522_R	911_G	0.628	0.44
652_D	868_I	0.627	0.44
559_D	865_F	0.626	0.44
123_H	420_H	0.626	0.44
56_S	93_N	0.626	0.44
29_V	276_A	0.626	0.44
119_R	258_Y	0.625	0.44
348_L	378_L	0.625	0.44
822_R	827_A	0.625	0.44
174_Y	187_S	0.624	0.44
615_L	620_G	0.624	0.44
358_F	372_H	0.623	0.43
324_L	356_I	0.623	0.43
684_K	849_T	0.622	0.43
166_L	190_P	0.622	0.43
443_F	467_L	0.621	0.43
929_A	933_A	0.621	0.43
162_H	415_R	0.620	0.43
628_L	649_L	0.620	0.43
718_V	815_D	0.620	0.43
142_Q	145_G	0.619	0.43
923_T	927_C	0.619	0.43
190_P	779_K	0.618	0.43
447_K	450_G	0.617	0.43
214_T	218_A	0.617	0.43
911_G	914_E	0.616	0.43
607_A	612_V	0.616	0.43
69_E	504_G	0.616	0.43
528_L	778_I	0.615	0.43
666_T	670_P	0.615	0.43
396_E	399_K	0.615	0.43
160_G	192_L	0.615	0.43
360_Y	372_H	0.614	0.43
599_E	896_K	0.614	0.43
175_I	492_A	0.614	0.43
654_L	886_V	0.614	0.43
469_F	473_V	0.613	0.42
723_A	778_I	0.613	0.42
218_A	774_E	0.613	0.42
528_L	571_V	0.612	0.42
112_F	228_S	0.611	0.42
627_T	630_L	0.611	0.42
451_Q	455_I	0.611	0.42
440_M	613_L	0.610	0.42
332_V	343_V	0.609	0.42
28_V	554_A	0.609	0.42
147_R	719_P	0.609	0.42
526_R	916_L	0.609	0.42
301_S	334_A	0.609	0.42
445_N	916_L	0.608	0.42
648_T	886_V	0.608	0.42
82_A	163_T	0.608	0.42
626_V	902_V	0.606	0.42
419_R	428_L	0.606	0.42
608_N	632_V	0.606	0.42
351_S	358_F	0.606	0.42
476_N	526_R	0.605	0.42
878_L	883_N	0.605	0.42
812_T	845_S	0.605	0.42
278_P	408_S	0.604	0.42
721_S	744_Q	0.604	0.42
215_Q	777_E	0.603	0.41
303_A	331_D	0.603	0.41
792_T	795_E	0.602	0.41
293_R	620_G	0.602	0.41
296_Q	299_E	0.602	0.41
788_V	795_E	0.601	0.41
124_D	255_I	0.601	0.41
151_L	233_V	0.600	0.41
552_R	938_P	0.599	0.41
177_A	203_V	0.599	0.41
131_T	137_D	0.598	0.41
293_R	402_S	0.598	0.41
484_A	492_A	0.598	0.41
598_I	868_I	0.597	0.41
296_Q	306_A	0.597	0.41
587_L	590_Q	0.597	0.41
79_L	109_R	0.596	0.41
918_S	923_T	0.596	0.41
328_Y	336_W	0.595	0.41
511_V	827_A	0.595	0.41
23_R	689_D	0.595	0.41
726_Y	729_G	0.594	0.41
167_E	171_S	0.594	0.41
849_T	883_N	0.594	0.41
794_E	798_E	0.594	0.41
928_E	937_K	0.594	0.41
130_Q	134_Q	0.593	0.40
769_K	786_H	0.593	0.40
674_R	678_G	0.593	0.40
86_E	541_V	0.593	0.40
267_L	415_R	0.592	0.40
803_V	883_N	0.592	0.40
285_V	403_N	0.591	0.40
144_E	211_D	0.591	0.40
263_L	418_A	0.590	0.40
162_H	166_L	0.590	0.40
678_G	681_H	0.589	0.40
84_S	714_L	0.588	0.40
615_L	886_V	0.588	0.40
900_W	920_T	0.588	0.40
306_A	310_W	0.588	0.40
313_R	318_F	0.588	0.40
183_V	203_V	0.588	0.40
875_L	879_R	0.587	0.40
25_K	923_T	0.587	0.40
576_P	589_G	0.587	0.40
684_K	850_G	0.586	0.40
599_E	926_E	0.586	0.40
683_D	850_G	0.585	0.40
285_V	884_T	0.585	0.40
186_L	190_P	0.585	0.40
5_E	75_H	0.585	0.40
296_Q	304_G	0.584	0.40
511_V	542_I	0.584	0.40
117_E	449_A	0.584	0.40
50_Q	55_E	0.583	0.39
410_E	767_K	0.583	0.39
665_A	673_Y	0.583	0.39
633_G	884_T	0.583	0.39
440_M	467_L	0.582	0.39
136_V	225_L	0.582	0.39
358_F	402_S	0.582	0.39
558_I	681_H	0.581	0.39
160_G	200_I	0.581	0.39
793_I	797_R	0.580	0.39
456_A	460_L	0.580	0.39
195_Q	754_H	0.580	0.39
317_Y	377_V	0.579	0.39
350_G	376_G	0.579	0.39
364_R	368_S	0.579	0.39
742_A	764_D	0.579	0.39
714_L	883_N	0.578	0.39
337_G	344_H	0.578	0.39
798_E	802_A	0.578	0.39
291_P	378_L	0.578	0.39
342_N	928_E	0.577	0.39
630_L	902_V	0.577	0.39
296_Q	307_I	0.577	0.39
255_I	258_Y	0.576	0.39
32_L	870_Q	0.575	0.39
222_E	730_R	0.575	0.39
75_H	458_K	0.575	0.39
348_L	377_V	0.574	0.39
135_M	249_A	0.574	0.39
118_P	251_F	0.574	0.39
580_I	593_S	0.574	0.39
551_I	580_I	0.574	0.39
310_W	377_V	0.573	0.38
917_V	933_A	0.573	0.38
528_L	707_V	0.573	0.38
358_F	368_S	0.573	0.38
281_D	396_E	0.573	0.38
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651_N	687_D	0.572	0.38
19_L	540_T	0.572	0.38
325_A	534_L	0.571	0.38
158_R	161_E	0.571	0.38
69_E	172_Q	0.571	0.38
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603_K	926_E	0.571	0.38
218_A	773_R	0.571	0.38
563_G	570_E	0.571	0.38
573_A	577_L	0.570	0.38
563_G	866_A	0.570	0.38
424_E	430_A	0.570	0.38
352_G	373_P	0.569	0.38
710_P	845_S	0.569	0.38
825_Q	829_T	0.569	0.38
658_A	670_P	0.569	0.38
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415_R	420_H	0.568	0.38
16_N	25_K	0.567	0.38
625_D	650_I	0.567	0.38
713_E	717_G	0.566	0.38
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901_I	928_E	0.566	0.38
658_A	886_V	0.565	0.38
226_E	249_A	0.565	0.38
46_Y	771_Y	0.565	0.38
380_N	385_Y	0.564	0.38
483_S	721_S	0.564	0.38
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258_Y	420_H	0.564	0.38
652_D	872_L	0.564	0.38
586_S	589_G	0.563	0.38
228_S	404_R	0.562	0.37
221_F	393_V	0.562	0.37
317_Y	380_N	0.562	0.37
6_V	331_D	0.561	0.37
220_S	718_V	0.561	0.37
451_Q	751_V	0.561	0.37
392_A	397_L	0.560	0.37
626_V	650_I	0.560	0.37
448_L	458_K	0.560	0.37
169_L	177_A	0.559	0.37
431_I	444_N	0.559	0.37
639_T	931_H	0.559	0.37
933_A	936_L	0.558	0.37
32_L	533_H	0.558	0.37
638_I	929_A	0.558	0.37
556_H	579_A	0.558	0.37
99_G	435_S	0.558	0.37
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679_L	685_V	0.557	0.37
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324_L	340_S	0.556	0.37
896_K	922_E	0.556	0.37
666_T	671_A	0.556	0.37
330_F	534_L	0.555	0.37
431_I	440_M	0.555	0.37
158_R	195_Q	0.555	0.37
139_V	630_L	0.555	0.37
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556_H	572_V	0.554	0.37
76_I	564_A	0.554	0.37
289_F	403_N	0.554	0.37
521_Q	935_F	0.553	0.37
139_V	150_L	0.553	0.37
718_V	784_T	0.553	0.37
662_L	682_F	0.552	0.36
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687_D	855_I	0.552	0.36
638_I	855_I	0.552	0.36
924_V	927_C	0.552	0.36
338_S	937_K	0.551	0.36
762_P	767_K	0.551	0.36
542_I	560_I	0.551	0.36
590_Q	869_Q	0.551	0.36
786_H	822_R	0.550	0.36
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55_E	62_R	0.549	0.36
159_K	781_K	0.549	0.36
695_R	828_T	0.549	0.36
320_M	358_F	0.548	0.36
120_C	442_F	0.548	0.36
629_T	674_R	0.548	0.36
294_V	348_L	0.548	0.36
635_F	879_R	0.548	0.36
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278_P	716_A	0.547	0.36
145_G	209_V	0.547	0.36
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43_D	50_Q	0.547	0.36
10_R	250_N	0.546	0.36
576_P	920_T	0.546	0.36
310_W	325_A	0.546	0.36
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191_K	615_L	0.545	0.36
26_L	841_A	0.545	0.36
54_V	82_A	0.545	0.36
127_L	485_E	0.545	0.36
134_Q	137_D	0.544	0.36
422_Y	425_N	0.544	0.36
932_T	936_L	0.544	0.36
161_E	197_K	0.543	0.36
251_F	260_M	0.543	0.36
651_N	754_H	0.543	0.36
525_E	532_I	0.542	0.36
298_P	341_A	0.542	0.36
70_K	436_I	0.541	0.35
110_L	264_E	0.541	0.35
684_K	852_T	0.541	0.35
393_V	396_E	0.540	0.35
137_D	218_A	0.540	0.35
309_G	381_M	0.540	0.35
315_F	319_Q	0.540	0.35
442_F	652_D	0.540	0.35
375_E	379_H	0.540	0.35
171_S	624_K	0.540	0.35
194_L	765_Q	0.540	0.35
390_S	401_I	0.540	0.35
320_M	400_F	0.539	0.35
263_L	267_L	0.539	0.35
601_P	921_P	0.539	0.35
916_L	927_C	0.539	0.35
521_Q	651_N	0.539	0.35
260_M	418_A	0.539	0.35
495_I	517_I	0.538	0.35
556_H	900_W	0.538	0.35
619_R	626_V	0.538	0.35
291_P	344_H	0.538	0.35
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42_F	516_S	0.537	0.35
663_N	671_A	0.537	0.35
551_I	868_I	0.536	0.35
648_T	651_N	0.536	0.35
237_M	243_E	0.536	0.35
438_H	796_A	0.536	0.35
293_R	309_G	0.535	0.35
39_S	44_T	0.535	0.35
125_V	245_L	0.535	0.35
499_S	653_T	0.534	0.35
534_L	865_F	0.534	0.35
360_Y	365_G	0.534	0.35
441_E	629_T	0.534	0.35
210_R	213_L	0.534	0.35
23_R	26_L	0.533	0.35
296_Q	309_G	0.533	0.35
620_G	652_D	0.533	0.35
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534_L	728_P	0.532	0.35
57_L	421_V	0.532	0.35
457_E	461_K	0.532	0.35
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599_E	873_D	0.531	0.35
503_A	870_Q	0.531	0.35
671_A	676_I	0.531	0.35
727_T	826_S	0.530	0.34
794_E	811_Q	0.530	0.34
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287_Q	403_N	0.530	0.34
851_Q	883_N	0.530	0.34
89_S	868_I	0.530	0.34
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264_E	267_L	0.529	0.34
19_L	585_E	0.529	0.34
560_I	935_F	0.529	0.34
308_R	868_I	0.529	0.34
683_D	852_T	0.529	0.34
388_T	401_I	0.528	0.34
748_V	826_S	0.528	0.34
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323_S	356_I	0.527	0.34
115_V	422_Y	0.527	0.34
780_Y	894_V	0.527	0.34
298_P	483_S	0.526	0.34
615_L	628_L	0.526	0.34
714_L	718_V	0.526	0.34
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301_S	325_A	0.526	0.34
436_I	440_M	0.526	0.34
628_L	673_Y	0.525	0.34
617_G	653_T	0.525	0.34
914_E	917_V	0.525	0.34
291_P	341_A	0.525	0.34
161_E	336_W	0.525	0.34
179_I	199_T	0.525	0.34
104_I	443_F	0.525	0.34
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586_S	592_M	0.524	0.34
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586_S	695_R	0.523	0.34
434_M	439_A	0.523	0.34
606_P	611_K	0.523	0.34
266_R	274_A	0.522	0.34
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300_L	349_Y	0.521	0.34
372_H	762_P	0.521	0.34
147_R	208_K	0.521	0.34
266_R	530_T	0.521	0.34
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557_V	574_E	0.520	0.33
363_D	366_D	0.520	0.33
648_T	671_A	0.519	0.33
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171_S	492_A	0.519	0.33
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83_I	708_F	0.518	0.33
595_K	675_D	0.518	0.33
150_L	180_D	0.518	0.33
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472_N	526_R	0.518	0.33
379_H	382_E	0.518	0.33
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516_S	746_D	0.518	0.33
652_D	887_V	0.518	0.33
407_A	787_E	0.517	0.33
584_P	590_Q	0.517	0.33
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352_G	355_N	0.515	0.33
99_G	436_I	0.515	0.33
567_H	570_E	0.515	0.33
334_A	337_G	0.515	0.33
325_A	335_P	0.515	0.33
748_V	793_I	0.515	0.33
290_D	293_R	0.514	0.33
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567_H	814_M	0.514	0.33
329_K	334_A	0.514	0.33
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810_L	823_L	0.514	0.33
498_A	507_G	0.514	0.33
541_V	637_C	0.514	0.33
784_T	788_V	0.514	0.33
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57_L	507_G	0.513	0.33
11_T	59_A	0.513	0.33
458_K	492_A	0.513	0.33
172_Q	190_P	0.513	0.33
249_A	751_V	0.513	0.33
47_A	55_E	0.513	0.33
603_K	607_A	0.512	0.33
299_E	661_Q	0.512	0.33
423_V	430_A	0.512	0.33
665_A	668_A	0.512	0.33
662_L	668_A	0.512	0.33
557_V	866_A	0.512	0.33
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324_L	339_L	0.512	0.33
611_K	634_L	0.512	0.33
17_I	806_L	0.512	0.33
262_E	266_R	0.511	0.33
319_Q	399_K	0.511	0.33
66_S	709_T	0.511	0.33
228_S	322_K	0.511	0.33
651_N	886_V	0.511	0.33
39_S	223_T	0.510	0.33
317_Y	374_F	0.510	0.33
416_R	422_Y	0.510	0.33
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926_E	929_A	0.510	0.33
459_I	752_E	0.510	0.33
618_A	673_Y	0.510	0.33
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423_V	553_A	0.509	0.33
292_D	672_P	0.509	0.33
618_A	648_T	0.509	0.33
448_L	455_I	0.509	0.33
485_E	509_M	0.509	0.33
186_L	297_N	0.509	0.33
6_V	233_V	0.509	0.33
32_L	564_A	0.508	0.32
86_E	718_V	0.508	0.32
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434_M	438_H	0.508	0.32
139_V	207_F	0.508	0.32
735_V	835_A	0.508	0.32
120_C	492_A	0.507	0.32
175_I	203_V	0.507	0.32
303_A	377_V	0.507	0.32
219_E	310_W	0.506	0.32
688_I	795_E	0.506	0.32
402_S	669_E	0.506	0.32
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162_H	178_R	0.506	0.32
511_V	802_A	0.506	0.32
657_I	886_V	0.506	0.32
169_L	227_L	0.505	0.32
526_R	671_A	0.505	0.32
117_E	254_P	0.505	0.32
511_V	659_Q	0.505	0.32
281_D	458_K	0.505	0.32
26_L	536_D	0.505	0.32
130_Q	838_V	0.505	0.32
581_M	584_P	0.504	0.32
140_L	213_L	0.504	0.32
294_V	310_W	0.504	0.32
171_S	511_V	0.504	0.32
541_V	754_H	0.504	0.32
564_A	840_L	0.504	0.32
69_E	760_Y	0.503	0.32
541_V	744_Q	0.503	0.32
272_N	786_H	0.502	0.32
123_H	257_G	0.502	0.32
551_I	744_Q	0.502	0.32
139_V	228_S	0.502	0.32
754_H	778_I	0.502	0.32
659_Q	662_L	0.502	0.32
123_H	826_S	0.501	0.32
580_I	586_S	0.501	0.32
150_L	220_S	0.501	0.32
551_I	573_A	0.501	0.32
635_F	876_H	0.501	0.32
452_R	464_G	0.501	0.32
606_P	612_V	0.501	0.32
440_M	579_A	0.500	0.32

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2r6fA	2	0.9447	100	0.28	Contact Map
3zqjA	1	0.9926	100	0.294	Contact Map
3pihA	2	0.883	100	0.296	Contact Map
2vf7A	2	0.8415	100	0.435	Contact Map
3ux8A	2	0.584	100	0.717	Contact Map
2iw3A	2	0.5287	100	0.886	Contact Map
4q9hA	1	0.5138	100	0.888	Contact Map
4f4cA	1	0.4947	100	0.89	Contact Map
3bk7A	1	0.5404	100	0.893	Contact Map
3ozxA	1	0.4702	100	0.894	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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