GREMLIN Database
PTW3C - PTS system N-acetylglucosamine-specific EIICBA component
UniProt: P09323 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG10635
Length: 648 (627)
Sequences: 557 (347)
Seq/√Len: 13.8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
585_L597_P7.3761.00
570_M599_L5.9911.00
605_Y609_N4.8921.00
587_E590_A4.8081.00
561_E591_Q4.7781.00
181_N233_F4.7601.00
506_T535_D4.5771.00
46_G50_D4.5531.00
250_F356_S4.5091.00
583_K600_E4.4071.00
523_K527_D4.3541.00
545_T591_Q4.3341.00
248_M264_L4.2201.00
243_G348_F4.1981.00
546_I558_L3.9491.00
547_V559_E3.8751.00
253_P371_D3.8321.00
601_M606_L3.7910.99
298_L354_V3.6980.99
508_D532_K3.6180.99
543_A594_A3.4590.99
512_L618_V3.4230.99
233_F315_F3.3600.99
356_S360_R3.3360.99
251_A360_R3.3180.99
183_L296_A3.2950.98
428_D441_K3.2870.98
542_A558_L3.2480.98
585_L600_E3.2090.98
181_N315_F3.1610.98
256_R372_K3.1500.98
365_K371_D3.0800.98
400_V462_M3.0190.97
605_Y610_A2.9240.97
515_V530_A2.8200.96
407_K421_A2.7990.96
593_S596_Q2.7710.95
619_C622_I2.7460.95
549_I584_R2.7380.95
261_G265_L2.6760.95
584_R599_L2.6760.95
251_A356_S2.6300.94
565_E621_N2.5950.94
293_L297_L2.5630.93
238_M272_F2.4940.92
518_E522_S2.4870.92
545_T559_E2.4610.92
146_A150_Y2.4510.91
597_P600_E2.4440.91
177_F292_Y2.4240.91
570_M601_M2.4050.91
606_L613_M2.3890.90
32_Q42_A2.3780.90
546_I549_I2.3540.90
543_A593_S2.3180.89
345_V349_A2.3040.89
537_I597_P2.3020.89
632_A640_Q2.2920.88
144_L148_F2.2760.88
218_R222_G2.2750.88
512_L523_K2.2600.88
250_F352_F2.2430.87
499_A562_K2.2400.87
546_I586_V2.2020.86
339_M342_V2.1420.85
107_V144_L2.1340.84
58_I77_A2.1330.84
549_I588_E2.1330.84
183_L236_I2.1230.84
529_V619_C2.1210.84
537_I600_E2.1190.84
179_F296_A2.0800.83
62_S106_L2.0660.82
341_L345_V2.0610.82
505_I538_V2.0360.81
194_N299_T2.0310.81
54_L80_Y2.0230.81
511_A514_Q2.0010.80
246_L250_F1.9510.78
422_D552_T1.9160.77
48_I78_V1.9130.77
512_L527_D1.9040.77
194_N233_F1.8690.75
212_F221_A1.8580.75
557_C620_S1.8220.73
79_G137_T1.8000.72
397_I466_V1.7990.72
592_V604_D1.7930.72
508_D635_H1.7930.72
329_N337_V1.7910.72
411_A455_A1.7810.71
294_L358_V1.7760.71
119_K454_K1.7760.71
622_I625_F1.7660.71
106_L110_A1.7580.70
206_N210_T1.7440.70
540_S558_L1.7340.69
516_P614_I1.7300.69
194_N315_F1.7040.68
506_T638_A1.6940.67
580_K609_N1.6830.67
525_V619_C1.6790.67
590_A596_Q1.6500.65
422_D425_R1.6490.65
8_Q11_G1.6390.65
566_I618_V1.6350.65
115_W280_L1.6210.64
325_A329_N1.6150.64
397_I409_I1.6010.63
506_T637_V1.5910.62
147_I151_V1.5820.62
592_V606_L1.5800.62
236_I299_T1.5780.62
181_N194_N1.5750.62
143_V147_I1.5650.61
392_L454_K1.5510.60
400_V449_V1.5420.60
350_I354_V1.5370.60
96_M159_I1.5310.59
516_P612_S1.5220.59
396_Y451_V1.5220.59
111_A140_F1.5020.58
249_Y257_R1.4980.58
50_D280_L1.4790.57
181_N299_T1.4790.57
118_I132_F1.4770.56
55_I315_F1.4700.56
250_F360_R1.4570.55
203_E207_A1.4560.55
506_T534_T1.4550.55
55_I183_L1.4550.55
411_A434_L1.4490.55
174_S228_M1.4450.55
179_F183_L1.4360.54
342_V346_I1.4330.54
304_F315_F1.4330.54
181_N236_I1.4250.54
243_G345_V1.4240.54
175_G179_F1.4220.54
549_I586_V1.4220.54
256_R259_M1.4130.53
604_D607_N1.4030.53
176_I236_I1.3890.52
537_I585_L1.3880.52
84_T93_E1.3860.52
54_L77_A1.3830.51
499_A560_T1.3810.51
181_N292_Y1.3780.51
580_K605_Y1.3760.51
49_F276_V1.3640.50
409_I466_V1.3540.50
181_N306_A1.3410.49
233_F299_T1.3270.48
62_S258_P1.3250.48
180_I193_L1.3250.48
413_I455_A1.3190.48
125_S276_V1.3160.48
111_A136_A1.3160.48
513_D523_K1.3130.48
156_Q229_F1.3060.47
15_Q191_Q1.3010.47
63_S197_A1.3000.47
305_V309_L1.3000.47
306_A311_I1.2990.47
331_P337_V1.2980.47
233_F306_A1.2950.47
139_F143_V1.2890.46
510_V532_K1.2880.46
525_V620_S1.2870.46
253_P365_K1.2800.46
112_Y227_G1.2780.46
233_F292_Y1.2770.46
26_L55_I1.2720.45
254_K257_R1.2630.45
26_L30_F1.2500.44
28_L49_F1.2350.44
542_A560_T1.2260.43
570_M584_R1.2240.43
404_D425_R1.2210.43
570_M615_S1.2210.43
78_V104_T1.2190.43
80_Y545_T1.2190.43
174_S307_T1.2140.42
332_A337_V1.2070.42
544_G558_L1.2020.42
551_N567_V1.1990.42
239_F344_G1.1970.41
521_A643_L1.1950.41
84_T94_I1.1900.41
516_P610_A1.1830.41
220_Y316_S1.1810.41
543_A561_E1.1740.40
524_A557_C1.1710.40
114_R117_D1.1670.40
248_M283_L1.1640.40
451_V459_G1.1630.40
503_S636_I1.1620.40
181_N298_L1.1460.39
270_T273_L1.1450.39
3_I371_D1.1420.39
257_R361_M1.1380.38
235_P306_A1.1370.38
151_V254_K1.1280.38
606_L644_Y1.1270.38
183_L299_T1.1240.38
505_I531_V1.1210.38
48_I290_L1.1190.37
183_L194_N1.1130.37
222_G337_V1.1130.37
215_D227_G1.1000.37
328_Y337_V1.0980.36
21_L61_A1.0980.36
58_I292_Y1.0970.36
230_M306_A1.0960.36
55_I233_F1.0950.36
510_V614_I1.0950.36
306_A315_F1.0940.36
25_A49_F1.0910.36
276_V306_A1.0890.36
570_M628_L1.0850.36
529_V643_L1.0830.36
235_P292_Y1.0810.36
97_G156_Q1.0810.36
210_T213_H1.0800.36
235_P302_S1.0780.35
218_R337_V1.0760.35
495_A618_V1.0760.35
174_S288_A1.0750.35
176_I183_L1.0740.35
558_L598_I1.0740.35
512_L625_F1.0660.35
599_L611_R1.0660.35
246_L356_S1.0650.35
374_D566_I1.0640.35
315_F319_A1.0630.35
629_I633_Q1.0630.35
636_I640_Q1.0620.35
209_G214_G1.0620.35
553_N584_R1.0610.35
516_P616_P1.0580.34
538_V601_M1.0580.34
576_A611_R1.0540.34
581_G609_N1.0530.34
525_V622_I1.0490.34
179_F293_L1.0490.34
148_F212_F1.0440.34
552_T615_S1.0430.34
181_N296_A1.0400.34
545_T594_A1.0360.33
9_R508_D1.0330.33
9_R113_N1.0330.33
12_R410_D1.0240.33
434_L455_A1.0180.33
218_R226_A1.0150.32
414_T533_P1.0150.32
354_V358_V1.0140.32
294_L298_L1.0130.32
230_M235_P1.0130.32
233_F285_M1.0100.32
309_L343_M1.0070.32
525_V568_V1.0040.32
155_V321_A1.0040.32
104_T148_F1.0030.32
170_G173_G1.0020.32
531_V560_T1.0000.32
163_G203_E0.9990.32
202_G226_A0.9970.32
252_A366_T0.9950.31
512_L524_A0.9880.31
313_A328_Y0.9880.31
221_A269_V0.9840.31
198_W237_M0.9780.31
559_E598_I0.9750.31
181_N285_M0.9750.31
233_F236_I0.9730.30
607_N637_V0.9720.30
409_I418_L0.9710.30
525_V557_C0.9710.30
218_R328_Y0.9710.30
14_L112_Y0.9690.30
183_L315_F0.9680.30
235_P295_H0.9680.30
512_L584_R0.9650.30
604_D608_A0.9650.30
619_C625_F0.9630.30
136_A139_F0.9600.30
158_A346_I0.9600.30
14_L215_D0.9600.30
25_A316_S0.9580.30
194_N236_I0.9580.30
532_K606_L0.9570.30
233_F298_L0.9570.30
601_M615_S0.9520.29
177_F312_H0.9520.29
215_D230_M0.9520.29
11_G63_S0.9510.29
324_Y337_V0.9460.29
155_V160_H0.9450.29
529_V630_I0.9390.29
80_Y437_S0.9390.29
358_V362_F0.9380.29
290_L294_L0.9320.29
236_I315_F0.9310.29
18_I264_L0.9300.29
618_V643_L0.9300.29
208_A280_L0.9290.28
488_K493_P0.9280.28
454_K458_I0.9240.28
631_K645_E0.9140.28
527_D622_I0.9140.28
420_V426_V0.9130.28
176_I315_F0.9090.28
290_L346_I0.9040.27
449_V455_A0.9040.27
43_Q86_A0.9030.27
568_V616_P0.9010.27
445_Q521_A0.9000.27
519_A553_N0.9000.27
299_T315_F0.8980.27
599_L610_A0.8960.27
194_N285_M0.8950.27
18_I197_A0.8930.27
400_V418_L0.8920.27
49_F100_A0.8910.27
29_R203_E0.8910.27
110_A115_W0.8910.27
138_G292_Y0.8900.27
115_W617_V0.8900.27
77_A292_Y0.8870.27
253_P373_E0.8860.27
249_Y261_G0.8830.26
429_T521_A0.8820.26
599_L605_Y0.8800.26
353_V357_L0.8780.26
55_I181_N0.8780.26
62_S251_A0.8780.26
178_G303_L0.8760.26
16_L62_S0.8750.26
456_E462_M0.8750.26
510_V530_A0.8740.26
576_A613_M0.8730.26
27_L41_I0.8720.26
532_K605_Y0.8690.26
406_L466_V0.8690.26
546_I572_I0.8690.26
549_I590_A0.8690.26
233_F296_A0.8670.26
391_Q521_A0.8670.26
581_G605_Y0.8640.26
536_K606_L0.8640.26
222_G328_Y0.8630.26
486_V493_P0.8630.26
362_F508_D0.8620.26
58_I639_G0.8620.26
556_F598_I0.8610.26
138_G234_F0.8600.26
236_I285_M0.8570.25
560_T572_I0.8560.25
512_L619_C0.8540.25
123_F169_A0.8530.25
411_A449_V0.8520.25
547_V596_Q0.8510.25
498_I643_L0.8500.25
611_R622_I0.8480.25
114_R562_K0.8470.25
14_L23_V0.8470.25
148_F257_R0.8460.25
232_G320_G0.8430.25
136_A140_F0.8430.25
151_V429_T0.8430.25
561_E640_Q0.8420.25
179_F236_I0.8410.25
564_A625_F0.8380.25
486_V491_A0.8380.25
420_V636_I0.8360.25
116_S340_L0.8360.25
539_V596_Q0.8340.24
576_A610_A0.8330.24
462_M465_V0.8300.24
67_D170_G0.8280.24
107_V248_M0.8270.24
183_L233_F0.8260.24
531_V630_I0.8230.24
177_F180_I0.8230.24
198_W320_G0.8230.24
157_H161_A0.8220.24
313_A340_L0.8220.24
485_P489_P0.8220.24
233_F304_F0.8210.24
207_A211_V0.8100.24
257_R583_K0.8100.24
536_K601_M0.8090.23
215_D295_H0.8080.23
276_V299_T0.8050.23
158_A540_S0.8020.23
229_F295_H0.8010.23
585_L615_S0.8000.23
581_G612_S0.8000.23
28_L100_A0.7990.23
324_Y340_L0.7980.23
603_L610_A0.7950.23
485_P488_K0.7950.23
587_E607_N0.7940.23
198_W318_S0.7920.23
420_V525_V0.7920.23
179_F299_T0.7890.23
155_V221_A0.7880.23
391_Q588_E0.7880.23
174_S263_M0.7870.23
421_A495_A0.7860.23
304_F308_L0.7850.23
345_V348_F0.7840.23
112_Y130_K0.7840.23
613_M632_A0.7840.23
594_A598_I0.7820.22
254_K352_F0.7800.22
9_R400_V0.7790.22
585_L596_Q0.7790.22
216_I222_G0.7790.22
547_V618_V0.7780.22
244_A351_Y0.7760.22
585_L599_L0.7740.22
570_M598_I0.7720.22
566_I619_C0.7690.22
84_T177_F0.7680.22
283_L305_V0.7670.22
233_F313_A0.7670.22
540_S543_A0.7670.22
139_F142_L0.7670.22
229_F273_L0.7660.22
162_G180_I0.7650.22
18_I162_G0.7650.22
214_G218_R0.7630.22
406_L475_S0.7630.22
508_D634_G0.7610.22
81_F137_T0.7610.22
19_A232_G0.7610.22
451_V455_A0.7600.22
489_P580_K0.7590.22
298_L301_I0.7580.22
237_M318_S0.7580.22
599_L609_N0.7560.21
124_L280_L0.7540.21
60_V219_F0.7540.21
9_R199_F0.7530.21
155_V643_L0.7520.21
183_L304_F0.7520.21
518_E594_A0.7520.21
165_W169_A0.7510.21
564_A643_L0.7510.21
492_V561_E0.7500.21
144_L363_N0.7490.21
48_I478_A0.7490.21
505_I568_V0.7480.21
27_L81_F0.7480.21
450_I618_V0.7470.21
285_M299_T0.7470.21
521_A597_P0.7470.21
55_I83_L0.7460.21
80_Y93_E0.7420.21
67_D112_Y0.7400.21
282_F581_G0.7400.21
181_N311_I0.7390.21
280_L626_S0.7390.21
394_T462_M0.7380.21
296_A301_I0.7360.21
560_T564_A0.7350.21
466_V469_G0.7330.21
512_L615_S0.7330.21
246_L251_A0.7330.21
244_A289_P0.7330.21
360_R365_K0.7330.21
125_S451_V0.7310.21
596_Q618_V0.7310.21
181_N283_L0.7310.21
22_P134_P0.7280.20
174_S315_F0.7270.20
346_I427_N0.7260.20
566_I598_I0.7260.20
82_V181_N0.7250.20
214_G226_A0.7230.20
27_L59_G0.7230.20
248_M287_L0.7230.20
514_Q613_M0.7230.20
556_F559_E0.7230.20
475_S604_D0.7220.20
197_A287_L0.7210.20
28_L118_I0.7200.20
218_R224_G0.7200.20
392_L434_L0.7190.20
19_A22_P0.7170.20
511_A521_A0.7170.20
82_V114_R0.7160.20
512_L547_V0.7160.20
534_T578_E0.7150.20
607_N613_M0.7150.20
60_V292_Y0.7140.20
9_R634_G0.7130.20
557_C567_V0.7130.20
398_A568_V0.7120.20
572_I613_M0.7110.20
504_P616_P0.7110.20
112_Y215_D0.7100.20
556_F568_V0.7100.20
229_F260_V0.7090.20
305_V342_V0.7090.20
174_S298_L0.7090.20
192_V226_A0.7080.20
419_T423_S0.7070.20
194_N216_I0.7070.20
503_S622_I0.7070.20
305_V308_L0.7070.20
50_D321_A0.7060.20
270_T306_A0.7060.20
48_I183_L0.7050.20
229_F283_L0.7050.20
242_P351_Y0.7050.20
175_G303_L0.7040.20
475_S496_V0.7010.20
163_G193_L0.7000.20
216_I219_F0.7000.20
516_P581_G0.6990.19
82_V212_F0.6990.19
99_L196_I0.6980.19
551_N565_E0.6970.19
290_L362_F0.6960.19
525_V598_I0.6960.19
30_F157_H0.6960.19
558_L565_E0.6940.19
519_A643_L0.6930.19
228_M312_H0.6930.19
508_D558_L0.6920.19
28_L32_Q0.6910.19
40_F50_D0.6900.19
501_L529_V0.6900.19
524_A531_V0.6890.19
37_N324_Y0.6890.19
619_C643_L0.6880.19
23_V343_M0.6880.19
31_G45_G0.6880.19
512_L551_N0.6870.19
159_I165_W0.6860.19
434_L451_V0.6850.19
181_N304_F0.6850.19
297_L564_A0.6830.19
147_I561_E0.6830.19
29_R32_Q0.6820.19
467_A618_V0.6820.19
534_T637_V0.6810.19
308_L325_A0.6790.19
198_W319_A0.6750.19
477_E493_P0.6750.19
196_I316_S0.6740.19
13_A64_W0.6740.19
130_K215_D0.6730.19
19_A219_F0.6730.19
245_A280_L0.6720.19
178_G198_W0.6720.19
179_F194_N0.6710.19
311_I339_M0.6710.19
123_F265_L0.6700.19
71_A285_M0.6700.19
478_A638_A0.6690.18
115_W221_A0.6690.18
489_P546_I0.6680.18
343_M346_I0.6680.18
260_V616_P0.6670.18
55_I142_L0.6660.18
83_L285_M0.6650.18
58_I73_A0.6650.18
7_F10_L0.6650.18
49_F220_Y0.6640.18
18_I192_V0.6630.18
237_M241_L0.6630.18
20_V47_A0.6630.18
114_R171_A0.6630.18
262_G443_N0.6620.18
167_V177_F0.6610.18
48_I82_V0.6600.18
543_A596_Q0.6600.18
295_H315_F0.6600.18
455_A462_M0.6590.18
115_W353_V0.6590.18
126_F131_R0.6580.18
50_D390_T0.6580.18
457_S460_D0.6580.18
60_V581_G0.6580.18
296_A299_T0.6570.18
407_K419_T0.6560.18
532_K607_N0.6560.18
16_L49_F0.6540.18
494_N618_V0.6540.18
513_D618_V0.6520.18
521_A608_A0.6520.18
254_K349_A0.6520.18
568_V615_S0.6500.18
230_M234_F0.6490.18
581_G585_L0.6470.18
553_N620_S0.6460.18
467_A498_I0.6450.18
532_K614_I0.6450.18
141_C338_W0.6440.18
138_G230_M0.6440.18
477_E490_Q0.6430.18
215_D338_W0.6430.18
409_I440_V0.6420.18
418_L449_V0.6410.18
527_D610_A0.6400.18
399_A434_L0.6380.18
488_K491_A0.6380.18
193_L285_M0.6380.18
147_I407_K0.6380.18
174_S194_N0.6380.18
151_V489_P0.6380.18
602_D605_Y0.6380.18
81_F118_I0.6370.17
319_A340_L0.6360.17
487_A490_Q0.6360.17
49_F270_T0.6360.17
298_L353_V0.6350.17
360_R591_Q0.6340.17
362_F596_Q0.6330.17
413_I434_L0.6330.17
374_D433_R0.6330.17
233_F311_I0.6330.17
598_I639_G0.6320.17
536_K603_L0.6310.17
521_A559_E0.6310.17
181_N216_I0.6310.17
509_V529_V0.6310.17
162_G176_I0.6310.17
170_G298_L0.6300.17
613_M616_P0.6290.17
299_T340_L0.6290.17
479_T493_P0.6290.17
377_V425_R0.6280.17
80_Y88_V0.6270.17
165_W321_A0.6270.17
612_S615_S0.6270.17
500_E619_C0.6250.17
518_E572_I0.6250.17
384_N474_A0.6250.17
173_G177_F0.6240.17
312_H335_Q0.6230.17
546_I645_E0.6230.17
511_A568_V0.6210.17
558_L572_I0.6210.17
522_S591_Q0.6210.17
498_I645_E0.6200.17
231_S312_H0.6200.17
350_I466_V0.6190.17
394_T398_A0.6170.17
19_A180_I0.6170.17
238_M313_A0.6160.17
497_S643_L0.6150.17
352_F356_S0.6150.17
440_V503_S0.6150.17
358_V539_V0.6140.17
566_I608_A0.6140.17
530_A614_I0.6140.17
476_A485_P0.6140.17
372_K547_V0.6130.17
458_I462_M0.6120.17
521_A537_I0.6120.17
174_S179_F0.6120.17
611_R619_C0.6110.17
97_G226_A0.6110.17
14_L31_G0.6100.17
168_S257_R0.6080.17
479_T489_P0.6080.17
107_V456_E0.6070.17
321_A396_Y0.6060.17
125_S203_E0.6060.17
531_V536_K0.6050.17
280_L467_A0.6040.16
312_H315_F0.6040.16
100_A270_T0.6040.16
506_T536_K0.6030.16
264_L288_A0.6030.16
497_S509_V0.6030.16
559_E591_Q0.6020.16
615_S639_G0.6010.16
62_S142_L0.6010.16
177_F309_L0.6010.16
22_P266_S0.6000.16
522_S618_V0.6000.16
604_D609_N0.6000.16
612_S622_I0.6000.16
546_I566_I0.6000.16
19_A327_M0.5990.16
506_T568_V0.5980.16
123_F128_G0.5970.16
73_A248_M0.5970.16
280_L506_T0.5960.16
630_I633_Q0.5960.16
415_R448_Q0.5950.16
525_V610_A0.5940.16
292_Y350_I0.5930.16
55_I160_H0.5920.16
404_D591_Q0.5910.16
83_L94_I0.5910.16
477_E491_A0.5910.16
43_Q46_G0.5900.16
313_A327_M0.5900.16
39_A42_A0.5900.16
125_S265_L0.5900.16
4_L8_Q0.5900.16
48_I217_N0.5890.16
9_R104_T0.5860.16
218_R223_D0.5860.16
477_E501_L0.5860.16
558_L621_N0.5860.16
236_I302_S0.5860.16
518_E539_V0.5850.16
548_K588_E0.5840.16
427_N540_S0.5840.16
535_D540_S0.5840.16
58_I617_V0.5830.16
413_I451_V0.5830.16
508_D534_T0.5820.16
46_G85_K0.5820.16
116_S169_A0.5810.16
539_V597_P0.5810.16
174_S233_F0.5810.16
200_Q455_A0.5780.16
238_M326_L0.5770.16
138_G295_H0.5770.16
586_V598_I0.5770.16
176_I364_L0.5760.16
561_E635_H0.5760.16
629_I643_L0.5750.16
32_Q94_I0.5750.16
524_A529_V0.5740.16
529_V564_A0.5740.16
236_I293_L0.5730.16
296_A403_T0.5730.16
619_C644_Y0.5730.16
474_A478_A0.5720.16
288_A394_T0.5720.16
371_D566_I0.5710.16
61_A135_I0.5710.16
451_V462_M0.5710.16
479_T617_V0.5700.15
86_A192_V0.5700.15
525_V567_V0.5690.15
216_I315_F0.5690.15
113_N462_M0.5680.15
584_R611_R0.5680.15
126_F134_P0.5680.15
477_E578_E0.5680.15
447_I598_I0.5670.15
25_A96_M0.5670.15
194_N296_A0.5660.15
503_S531_V0.5650.15
194_N340_L0.5650.15
271_A521_A0.5650.15
136_A624_D0.5650.15
231_S307_T0.5650.15
138_G235_P0.5650.15
293_L350_I0.5640.15
478_A608_A0.5640.15
14_L227_G0.5640.15
610_A622_I0.5640.15
585_L593_S0.5630.15
512_L559_E0.5630.15
537_I630_I0.5620.15
266_S459_G0.5620.15
476_A491_A0.5620.15
125_S434_L0.5610.15
58_I283_L0.5610.15
551_N606_L0.5600.15
80_Y258_P0.5580.15
422_D565_E0.5580.15
76_G459_G0.5580.15
295_H351_Y0.5580.15
594_A607_N0.5580.15
609_N612_S0.5570.15
522_S535_D0.5570.15
14_L207_A0.5570.15
230_M295_H0.5570.15
293_L304_F0.5560.15
200_Q203_E0.5550.15
542_A566_I0.5550.15
187_T453_A0.5550.15
177_F215_D0.5550.15
578_E598_I0.5540.15
529_V644_Y0.5540.15
166_I263_M0.5540.15
222_G329_N0.5530.15
611_R625_F0.5530.15
64_W125_S0.5530.15
130_K227_G0.5520.15
50_D501_L0.5520.15
16_L118_I0.5520.15
522_S576_A0.5510.15
16_L328_Y0.5500.15
13_A79_G0.5500.15
262_G612_S0.5490.15
248_M260_V0.5490.15
77_A558_L0.5480.15
80_Y512_L0.5480.15
264_L366_T0.5480.15
58_I305_V0.5480.15
29_R342_V0.5470.15
267_V288_A0.5460.15
447_I473_A0.5460.15
505_I616_P0.5460.15
546_I578_E0.5460.15
433_R624_D0.5460.15
429_T488_K0.5460.15
395_N433_R0.5440.15
216_I335_Q0.5440.15
503_S521_A0.5430.15
19_A280_L0.5420.15
604_D629_I0.5400.15
155_V386_E0.5400.15
384_N477_E0.5390.15
395_N430_M0.5390.15
489_P492_V0.5380.15
216_I340_L0.5380.15
69_A112_Y0.5380.15
8_Q410_D0.5370.15
59_G226_A0.5370.15
82_V233_F0.5360.15
411_A458_I0.5350.15
408_A419_T0.5330.14
71_A340_L0.5330.14
176_I181_N0.5330.14
488_K495_A0.5320.14
562_K587_E0.5320.14
65_S539_V0.5320.14
253_P547_V0.5310.14
220_Y234_F0.5310.14
486_V489_P0.5310.14
521_A532_K0.5310.14
599_L616_P0.5310.14
512_L643_L0.5310.14
269_V453_A0.5300.14
10_L166_I0.5300.14
195_T199_F0.5300.14
582_F598_I0.5300.14
499_A629_I0.5300.14
28_L31_G0.5300.14
200_Q243_G0.5300.14
218_R313_A0.5300.14
177_F231_S0.5290.14
132_F136_A0.5290.14
393_A446_T0.5290.14
39_A115_W0.5290.14
73_A183_L0.5280.14
503_S506_T0.5280.14
547_V588_E0.5280.14
203_E228_M0.5280.14
80_Y213_H0.5280.14
510_V633_Q0.5270.14
382_N386_E0.5270.14
612_S616_P0.5260.14
512_L628_L0.5260.14
630_I634_G0.5260.14
6_F60_V0.5250.14
113_N552_T0.5240.14
163_G173_G0.5230.14
162_G174_S0.5230.14
50_D534_T0.5230.14
545_T588_E0.5230.14
149_G292_Y0.5230.14
234_F344_G0.5230.14
583_K599_L0.5220.14
119_K276_V0.5220.14
233_F295_H0.5220.14
76_G292_Y0.5220.14
88_V260_V0.5220.14
474_A600_E0.5220.14
547_V584_R0.5220.14
48_I55_I0.5210.14
198_W232_G0.5210.14
605_Y611_R0.5200.14
384_N608_A0.5200.14
101_G105_G0.5200.14
64_W107_V0.5190.14
159_I162_G0.5190.14
385_T503_S0.5180.14
105_G126_F0.5180.14
235_P616_P0.5180.14
178_G232_G0.5180.14
509_V540_S0.5170.14
349_A353_V0.5160.14
253_P549_I0.5160.14
566_I591_Q0.5160.14
552_T572_I0.5160.14
29_R331_P0.5150.14
568_V617_V0.5140.14
327_M337_V0.5140.14
362_F613_M0.5140.14
71_A459_G0.5140.14
306_A322_I0.5130.14
174_S312_H0.5130.14
197_A264_L0.5130.14
195_T298_L0.5120.14
462_M598_I0.5110.14
577_L605_Y0.5110.14
134_P214_G0.5110.14
477_E593_S0.5100.14
342_V357_L0.5100.14
419_T538_V0.5090.14
242_P344_G0.5090.14
321_A501_L0.5090.14
537_I638_A0.5090.14
141_C451_V0.5090.14
9_R140_F0.5080.14
545_T567_V0.5080.14
162_G165_W0.5080.14
4_L11_G0.5080.14
9_R456_E0.5070.14
54_L81_F0.5070.14
490_Q608_A0.5070.14
549_I598_I0.5070.14
48_I122_D0.5060.14
406_L472_A0.5060.14
38_V222_G0.5060.14
506_T580_K0.5060.14
200_Q204_F0.5050.14
292_Y354_V0.5050.14
519_A621_N0.5040.14
181_N295_H0.5040.14
59_G370_E0.5040.14
511_A518_E0.5030.14
502_V594_A0.5030.14
400_V508_D0.5030.14
627_G645_E0.5020.14
522_S593_S0.5020.14
510_V587_E0.5010.14
177_F342_V0.5010.14
488_K498_I0.5010.14
29_R218_R0.5010.14
104_T144_L0.5010.14
27_L47_A0.5010.14
144_L634_G0.5000.14
196_I267_V0.5000.14
187_T319_A0.5000.14
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3ourB 1 0.2315 100 0.806 Contact Map
1f3zA 2 0.2315 100 0.806 Contact Map
2gprA 1 0.2377 100 0.806 Contact Map
1ax3A 1 0.25 100 0.811 Contact Map
3qnqA 2 0.5617 100 0.813 Contact Map
1ibaA 1 0.1204 99.9 0.912 Contact Map
3bp3A 1 0.125 99.9 0.913 Contact Map
3ipjA 1 0.1435 99.9 0.918 Contact Map
1dczA 1 0.1188 98.6 0.963 Contact Map
2d5dA 1 0.108 98.5 0.963 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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