GREMLIN Database
YJAB - Uncharacterized N-acetyltransferase YjaB
UniProt: P09163 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG11207
Length: 147 (128)
Sequences: 6708 (5364)
Seq/√Len: 474.1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
22_R79_D3.2561.00
6_R56_V3.2561.00
89_R120_V3.2401.00
96_L122_F2.6901.00
53_W94_H2.5731.00
66_M95_A2.5731.00
55_A87_V2.3981.00
114_V118_K2.3401.00
6_R12_E2.2581.00
64_G78_I2.2231.00
63_V82_V2.1091.00
54_V62_P1.9981.00
57_N82_V1.9501.00
92_V120_V1.8841.00
66_M73_M1.8791.00
94_H97_S1.7441.00
124_V127_R1.7151.00
18_A22_R1.7021.00
93_E120_V1.6811.00
19_I62_P1.6801.00
57_N63_V1.6471.00
115_G118_K1.6301.00
8_S16_L1.6101.00
83_R112_Q1.5921.00
114_V124_V1.5671.00
118_K124_V1.5401.00
26_A80_P1.5281.00
15_E18_A1.5071.00
82_V85_C1.5041.00
94_H98_M1.4861.00
35_Y39_L1.4301.00
21_C25_D1.4131.00
19_I23_S1.3991.00
56_V60_D1.3881.00
71_Q99_A1.3781.00
22_R80_P1.3661.00
57_N85_C1.3391.00
69_S74_D1.3181.00
108_E127_R1.3101.00
63_V87_V1.2901.00
5_I53_W1.2741.00
61_Q79_D1.2481.00
68_L99_A1.2481.00
68_L95_A1.2461.00
8_S54_V1.2291.00
56_V62_P1.2231.00
72_H103_T1.2231.00
89_R93_E1.2161.00
55_A63_V1.1941.00
8_S13_G1.1881.00
104_T117_Y1.1781.00
52_L67_L1.1731.00
61_Q82_V1.1411.00
33_A37_T1.1401.00
15_E62_P1.1311.00
57_N61_Q1.1111.00
98_M101_E1.0971.00
79_D82_V1.0731.00
40_E44_R1.0731.00
7_R98_M1.0641.00
67_L75_A1.0601.00
102_L122_F1.0401.00
23_S77_F1.0371.00
36_R40_E1.0311.00
20_W65_F1.0281.00
61_Q81_D1.0211.00
96_L102_L1.0201.00
15_E19_I1.0171.00
22_R81_D1.0131.00
35_Y38_E1.0091.00
15_E61_Q1.0011.00
89_R119_K0.9981.00
23_S83_R0.9831.00
93_E97_S0.9801.00
19_I79_D0.9541.00
26_A83_R0.9531.00
77_F116_F0.9511.00
16_L65_F0.9491.00
14_E18_A0.9421.00
68_L98_M0.9251.00
7_R53_W0.9231.00
28_H33_A0.9041.00
113_A117_Y0.8991.00
29_D32_S0.8901.00
47_L50_A0.8891.00
104_T113_A0.8821.00
17_V21_C0.8771.00
30_F34_E0.8681.00
73_M92_V0.8651.00
13_G17_V0.8531.00
78_I87_V0.8411.00
96_L120_V0.8351.00
116_F119_K0.8331.00
36_R39_L0.8301.00
18_A79_D0.8301.00
8_S12_E0.8291.00
27_T83_R0.8261.00
84_G119_K0.8221.00
82_V87_V0.8041.00
20_W75_A0.7821.00
111_E115_G0.7751.00
4_S56_V0.7711.00
53_W98_M0.7651.00
97_S101_E0.7621.00
20_W23_S0.7561.00
14_E44_R0.7471.00
39_L42_L0.7431.00
66_M91_L0.7391.00
6_R54_V0.7391.00
110_N113_A0.7331.00
76_L92_V0.7311.00
93_E96_L0.7311.00
20_W24_V0.7221.00
5_I94_H0.7181.00
75_A107_N0.7161.00
106_V110_N0.7131.00
32_S36_R0.7111.00
105_N128_S0.7091.00
32_S35_Y0.7051.00
20_W77_F0.7001.00
116_F120_V0.6931.00
78_I91_L0.6891.00
40_E43_V0.6851.00
84_G112_Q0.6831.00
41_D45_S0.6791.00
24_V77_F0.6771.00
29_D33_A0.6701.00
110_N117_Y0.6701.00
99_A102_L0.6621.00
73_M122_F0.6581.00
20_W43_V0.6571.00
22_R25_D0.6551.00
106_V114_V0.6511.00
64_G91_L0.6491.00
106_V113_A0.6431.00
96_L100_P0.6421.00
31_L34_E0.6391.00
12_E56_V0.6371.00
17_V20_W0.6351.00
16_L62_P0.6351.00
92_V116_F0.6331.00
109_Q114_V0.6321.00
52_L56_V0.6260.99
21_C40_E0.6190.99
70_G103_T0.6110.99
43_V46_F0.6060.99
5_I91_L0.6060.99
31_L36_R0.6060.99
55_A91_L0.6040.99
30_F109_Q0.6030.99
53_W66_M0.6030.99
118_K123_K0.6000.99
51_P99_A0.5990.99
80_P83_R0.5950.99
47_L51_P0.5920.99
87_V90_V0.5920.99
55_A64_G0.5900.99
9_R12_E0.5860.99
77_F107_N0.5840.99
7_R51_P0.5810.99
73_M76_L0.5790.99
104_T110_N0.5770.99
4_S7_R0.5760.99
17_V40_E0.5760.99
10_H13_G0.5730.99
24_V27_T0.5630.99
76_L117_Y0.5620.99
90_V97_S0.5610.99
92_V117_Y0.5600.99
64_G87_V0.5590.99
72_H75_A0.5470.99
24_V75_A0.5450.99
92_V122_F0.5440.99
43_V47_L0.5390.98
90_V93_E0.5380.98
63_V79_D0.5330.98
8_S52_L0.5290.98
42_L45_S0.5290.98
111_E114_V0.5240.98
46_F51_P0.5230.98
34_E37_T0.5210.98
87_V91_L0.5200.98
18_A61_Q0.5190.98
14_E40_E0.5190.98
30_F35_Y0.5170.98
13_G43_V0.5130.98
72_H105_N0.5120.98
31_L35_Y0.5110.98
25_D37_T0.5070.98
73_M117_Y0.5050.98
25_D36_R0.5020.98
84_G115_G0.5000.98
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2kcwA 1 1 99.9 0.267 Contact Map
3fncA 2 0.9864 99.8 0.325 Contact Map
2j8mA 2 0.9932 99.8 0.347 Contact Map
2cy2A 1 0.9864 99.8 0.359 Contact Map
2qecA 2 0.9864 99.8 0.36 Contact Map
1tiqA 1 0.9728 99.8 0.361 Contact Map
3i9sA 4 0.966 99.8 0.364 Contact Map
3dr6A 2 0.9864 99.8 0.365 Contact Map
3kkwA 1 0.966 99.8 0.376 Contact Map
2fiwA 2 0.9864 99.8 0.378 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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