XYLB - ECOLI - GREMLIN Contacts

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XYLB - Xylulose kinase

UniProt:	P09099	Sequences: MYIGIDLGTSGVKVILLNEQGEVVAAQTEKLTVSRPHPLWSEQDPEQWWQATDRAMKALGDQHSLQDVKALGIAGQMHGATLLDAQQRVLRPAILWNDGRCAQECTLLEARVPQSRVITGNLMMPGFTAPKLLWVQRHEPEIFRQIDKVLLPKDYLRLRMTGEFASDMSDAAGTMWLDVAKRDWSDVMLQACDLSRDQMPALYEGSEITGALLPEVAKAWGMATVPVVAGGGDNAAGAVGVGMVDANQAMLSLGTSGVYFAVSEGFLSKPESAVHSFCHALPQRWHLMSVMLSAASCLDWAAKLTGLSNVPALIAAAQQADESAEPVWFLPYLSGERTPHNNPQAKGVFFGLTHQHGPNELARAVLEGVGYALADGMDVVHACGIKPQSVTLIGGGARSEYWRQMLADISGQQLDYRTGGDVGPALGAARLAQIAANPEKSLIELLPQLPLEQSHLPDAQRYAAYQPRRETFRRLYQQLLPLMA	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG11075
Length:	484 (469)
Sequences:	12486 (8510)
Seq/√Len:	392.9

ECOLI - XYLB LYXK ARAB LSRK GLPK RHAB FUCK YGCE
BACSU - GNTK XYLB ARAB GLPK YOAC RHAB
HALSA - GLPK
SULSO - GLPK1 GLPK2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
186_D	196_R	4.316	1.00
104_E	137_R	3.933	1.00
18_N	22_E	3.537	1.00
14_V	55_A	3.404	1.00
107_L	137_R	3.336	1.00
374_A	469_R	2.947	1.00
404_Q	408_D	2.935	1.00
178_D	181_K	2.924	1.00
374_A	378_D	2.868	1.00
381_H	412_Q	2.860	1.00
118_I	185_S	2.856	1.00
413_Q	456_L	2.789	1.00
90_L	142_I	2.761	1.00
34_S	92_P	2.761	1.00
29_E	54_R	2.754	1.00
349_F	361_L	2.731	1.00
177_L	202_L	2.710	1.00
441_S	444_E	2.697	1.00
27_Q	58_A	2.633	1.00
389_S	415_D	2.623	1.00
29_E	58_A	2.619	1.00
440_K	444_E	2.609	1.00
91_R	139_E	2.551	1.00
204_E	207_E	2.548	1.00
49_W	159_R	2.523	1.00
85_A	147_D	2.469	1.00
400_E	453_Q	2.460	1.00
46_E	159_R	2.452	1.00
84_D	145_Q	2.428	1.00
16_L	59_L	2.419	1.00
183_D	196_R	2.391	1.00
189_L	196_R	2.379	1.00
374_A	466_Q	2.341	1.00
178_D	185_S	2.269	1.00
186_D	190_Q	2.221	1.00
231_G	236_A	2.185	1.00
163_E	201_A	2.172	1.00
157_R	230_G	2.149	1.00
15_I	425_A	2.144	1.00
5_I	52_T	2.116	1.00
325_E	360_E	2.109	1.00
148_K	164_F	2.079	1.00
11_G	28_T	2.067	1.00
213_L	216_V	2.044	1.00
458_D	461_R	2.038	1.00
297_C	365_V	2.026	1.00
107_L	111_R	1.983	1.00
320_A	360_E	1.974	1.00
411_G	462_Y	1.967	1.00
46_E	88_R	1.947	1.00
161_T	227_V	1.936	1.00
32_T	47_Q	1.934	1.00
58_A	62_Q	1.925	1.00
357_G	360_E	1.923	1.00
329_F	349_F	1.916	1.00
328_W	471_T	1.915	1.00
392_L	403_R	1.914	1.00
257_G	294_A	1.903	1.00
418_T	450_P	1.903	1.00
3_I	56_M	1.902	1.00
37_H	40_W	1.894	1.00
381_H	386_K	1.892	1.00
469_R	473_R	1.858	1.00
3_I	14_V	1.846	1.00
7_L	12_V	1.824	1.00
301_A	365_V	1.790	1.00
118_I	187_V	1.776	1.00
133_L	137_R	1.771	1.00
203_Y	207_E	1.763	1.00
415_D	454_S	1.740	1.00
82_L	135_V	1.731	1.00
165_A	203_Y	1.715	1.00
87_Q	158_L	1.703	1.00
84_D	88_R	1.693	1.00
106_T	110_A	1.672	1.00
315_A	319_Q	1.660	1.00
408_D	461_R	1.657	1.00
208_I	211_A	1.652	1.00
228_V	435_A	1.648	1.00
248_Q	389_S	1.642	1.00
408_D	458_D	1.634	1.00
208_I	228_V	1.611	1.00
413_Q	454_S	1.598	1.00
371_Y	468_R	1.591	1.00
103_Q	107_L	1.580	1.00
299_D	303_K	1.576	1.00
462_Y	466_Q	1.574	1.00
16_L	63_H	1.568	1.00
81_T	152_P	1.556	1.00
82_L	198_Q	1.551	1.00
378_D	473_R	1.530	1.00
460_Q	463_A	1.518	1.00
34_S	47_Q	1.518	1.00
246_A	264_E	1.512	1.00
346_K	353_T	1.510	1.00
141_E	144_R	1.507	1.00
180_A	266_F	1.491	1.00
44_D	47_Q	1.473	1.00
320_A	359_N	1.470	1.00
378_D	381_H	1.469	1.00
25_A	62_Q	1.449	1.00
27_Q	59_L	1.448	1.00
157_R	209_T	1.438	1.00
433_Q	439_E	1.437	1.00
27_Q	55_A	1.429	1.00
310_V	313_L	1.429	1.00
59_L	63_H	1.429	1.00
363_R	367_E	1.426	1.00
2_Y	433_Q	1.416	1.00
25_A	59_L	1.413	1.00
46_E	50_Q	1.406	1.00
134_W	138_H	1.400	1.00
2_Y	438_P	1.386	1.00
418_T	452_E	1.382	1.00
400_E	416_Y	1.375	1.00
401_Y	405_M	1.374	1.00
83_L	150_L	1.372	1.00
49_W	53_D	1.371	1.00
400_E	455_H	1.369	1.00
70_A	432_A	1.368	1.00
195_S	198_Q	1.364	1.00
161_T	210_G	1.363	1.00
316_A	319_Q	1.356	1.00
211_A	224_T	1.356	1.00
155_Y	159_R	1.355	1.00
253_L	406_L	1.344	1.00
389_S	413_Q	1.340	1.00
25_A	63_H	1.339	1.00
77_M	232_G	1.334	1.00
109_E	114_Q	1.334	1.00
168_M	182_R	1.334	1.00
5_I	56_M	1.333	1.00
370_G	405_M	1.328	1.00
329_F	333_L	1.307	1.00
370_G	409_I	1.306	1.00
251_L	406_L	1.305	1.00
102_A	106_T	1.301	1.00
189_L	199_M	1.295	1.00
12_V	52_T	1.288	1.00
249_A	387_P	1.288	1.00
329_F	365_V	1.271	1.00
312_A	315_A	1.268	1.00
157_R	165_A	1.264	1.00
291_M	372_A	1.260	1.00
317_A	401_Y	1.259	1.00
104_E	133_L	1.251	1.00
370_G	406_L	1.249	1.00
19_E	438_P	1.248	1.00
129_A	192_C	1.246	1.00
139_E	142_I	1.233	1.00
463_A	467_P	1.231	1.00
203_Y	209_T	1.225	1.00
136_Q	143_F	1.223	1.00
79_G	93_A	1.220	1.00
12_V	51_A	1.211	1.00
416_Y	455_H	1.207	1.00
208_I	226_P	1.204	1.00
309_N	313_L	1.204	1.00
111_R	191_A	1.201	1.00
309_N	312_A	1.191	1.00
50_Q	54_R	1.190	1.00
405_M	409_I	1.181	1.00
378_D	469_R	1.181	1.00
350_F	475_L	1.180	1.00
87_Q	164_F	1.178	1.00
231_G	431_L	1.173	1.00
403_R	455_H	1.165	1.00
323_S	326_P	1.165	1.00
375_D	473_R	1.164	1.00
411_G	466_Q	1.156	1.00
5_I	14_V	1.156	1.00
17_L	23_V	1.156	1.00
2_Y	436_A	1.155	1.00
105_C	123_M	1.154	1.00
305_T	361_L	1.153	1.00
60_G	65_L	1.151	1.00
245_D	446_L	1.151	1.00
42_E	92_P	1.150	1.00
44_D	92_P	1.149	1.00
335_G	338_T	1.148	1.00
143_F	146_I	1.148	1.00
60_G	63_H	1.144	1.00
187_V	190_Q	1.143	1.00
327_V	356_H	1.143	1.00
54_R	58_A	1.139	1.00
150_L	164_F	1.137	1.00
165_A	209_T	1.136	1.00
312_A	316_A	1.136	1.00
82_L	146_I	1.135	1.00
374_A	410_S	1.133	1.00
248_Q	391_T	1.126	1.00
208_I	435_A	1.123	1.00
466_Q	470_E	1.119	1.00
245_D	248_Q	1.119	1.00
461_R	464_A	1.114	1.00
451_L	454_S	1.114	1.00
311_P	314_I	1.105	1.00
356_H	360_E	1.104	1.00
48_W	152_P	1.102	1.00
293_S	297_C	1.100	1.00
168_M	202_L	1.095	1.00
141_E	145_Q	1.095	1.00
52_T	156_L	1.091	1.00
352_L	356_H	1.082	1.00
112_V	115_S	1.081	1.00
146_I	198_Q	1.078	1.00
391_T	415_D	1.075	1.00
103_Q	106_T	1.074	1.00
245_D	443_I	1.073	1.00
168_M	177_L	1.071	1.00
117_V	268_S	1.067	1.00
45_P	81_T	1.065	1.00
33_V	43_Q	1.065	1.00
70_A	436_A	1.065	1.00
293_S	296_S	1.061	1.00
82_L	132_L	1.060	1.00
17_L	429_A	1.055	1.00
73_I	157_R	1.052	1.00
247_N	388_Q	1.052	1.00
471_T	474_R	1.049	1.00
106_T	109_E	1.046	1.00
316_A	358_P	1.041	1.00
47_Q	50_Q	1.037	1.00
430_R	445_L	1.036	1.00
104_E	138_H	1.032	1.00
100_R	134_W	1.031	1.00
245_D	388_Q	1.028	1.00
314_I	399_S	1.028	1.00
91_R	142_I	1.027	1.00
41_S	97_N	1.026	1.00
377_M	410_S	1.025	1.00
27_Q	62_Q	1.025	1.00
434_I	445_L	1.024	1.00
189_L	194_L	1.018	1.00
31_L	51_A	1.017	1.00
371_Y	409_I	1.017	1.00
369_V	396_G	1.014	1.00
308_S	312_A	1.011	1.00
52_T	56_M	1.011	1.00
433_Q	438_P	1.005	1.00
129_A	175_M	1.003	1.00
70_A	228_V	1.001	1.00
313_L	317_A	0.998	1.00
347_G	352_L	0.996	1.00
398_R	420_G	0.995	1.00
249_A	261_A	0.993	1.00
53_D	57_K	0.991	1.00
107_L	110_A	0.990	1.00
336_E	339_P	0.989	1.00
458_D	462_Y	0.988	1.00
245_D	447_P	0.988	1.00
317_A	320_A	0.984	1.00
104_E	107_L	0.980	1.00
74_A	424_P	0.979	1.00
58_A	61_D	0.978	1.00
14_V	59_L	0.976	1.00
132_L	149_V	0.976	1.00
430_R	449_L	0.976	1.00
57_K	61_D	0.975	1.00
71_L	225_V	0.970	1.00
297_C	329_F	0.967	1.00
352_L	361_L	0.966	1.00
18_N	24_V	0.965	1.00
315_A	318_Q	0.962	1.00
396_G	402_W	0.959	1.00
306_G	358_P	0.957	1.00
16_L	68_V	0.956	1.00
168_M	280_A	0.953	1.00
314_I	362_A	0.952	1.00
182_R	204_E	0.946	1.00
3_I	16_L	0.941	1.00
113_P	191_A	0.939	1.00
88_R	159_R	0.938	1.00
316_A	359_N	0.938	1.00
146_I	149_V	0.937	1.00
332_Y	335_G	0.935	1.00
69_K	436_A	0.931	1.00
271_E	382_A	0.930	1.00
374_A	409_I	0.930	1.00
82_L	149_V	0.929	1.00
166_S	171_A	0.929	1.00
158_L	164_F	0.928	1.00
250_M	393_I	0.927	1.00
211_A	226_P	0.926	1.00
444_E	447_P	0.924	1.00
259_Y	377_M	0.923	1.00
411_G	464_A	0.923	1.00
317_A	359_N	0.921	1.00
117_V	180_A	0.920	1.00
140_P	144_R	0.920	1.00
177_L	181_K	0.918	1.00
17_L	426_L	0.918	1.00
142_I	145_Q	0.917	1.00
265_G	284_R	0.916	1.00
363_R	401_Y	0.914	1.00
228_V	436_A	0.912	1.00
3_I	68_V	0.909	1.00
107_L	133_L	0.908	1.00
371_Y	469_R	0.906	1.00
60_G	68_V	0.906	1.00
439_E	445_L	0.906	1.00
329_F	364_A	0.905	1.00
459_A	462_Y	0.901	1.00
317_A	362_A	0.900	1.00
319_Q	359_N	0.897	1.00
147_D	197_D	0.894	1.00
389_S	454_S	0.893	1.00
410_S	413_Q	0.893	1.00
459_A	464_A	0.892	1.00
257_G	373_L	0.892	1.00
72_G	228_V	0.883	1.00
378_D	382_A	0.883	1.00
154_D	166_S	0.882	1.00
64_S	67_D	0.881	1.00
133_L	136_Q	0.878	1.00
390_V	410_S	0.876	1.00
91_R	135_V	0.875	1.00
68_V	225_V	0.874	1.00
129_A	176_W	0.874	1.00
168_M	204_E	0.874	1.00
180_A	268_S	0.871	1.00
7_L	156_L	0.870	1.00
308_S	314_I	0.868	1.00
162_G	213_L	0.864	1.00
315_A	400_E	0.864	1.00
135_V	142_I	0.863	1.00
80_A	149_V	0.858	1.00
328_W	350_F	0.858	1.00
459_A	463_A	0.855	1.00
73_I	156_L	0.854	1.00
29_E	55_A	0.849	1.00
316_A	320_A	0.848	1.00
203_Y	229_A	0.845	1.00
184_W	199_M	0.841	1.00
166_S	200_P	0.840	1.00
78_H	173_G	0.839	1.00
105_C	125_P	0.834	1.00
165_A	201_A	0.833	1.00
237_G	393_I	0.832	1.00
169_S	279_H	0.831	1.00
171_A	184_W	0.828	1.00
99_G	124_M	0.825	1.00
404_Q	458_D	0.824	1.00
318_Q	401_Y	0.820	1.00
214_P	224_T	0.818	1.00
377_M	381_H	0.817	1.00
77_M	170_D	0.817	1.00
264_E	284_R	0.817	1.00
83_L	87_Q	0.813	1.00
66_Q	223_A	0.812	1.00
30_K	299_D	0.812	1.00
467_P	470_E	0.812	1.00
105_C	130_P	0.810	1.00
151_L	174_T	0.807	1.00
434_I	442_L	0.806	1.00
73_I	160_M	0.805	1.00
324_A	328_W	0.804	1.00
109_E	123_M	0.800	1.00
349_F	365_V	0.799	1.00
56_M	60_G	0.798	1.00
183_D	201_A	0.798	1.00
7_L	52_T	0.797	1.00
397_A	420_G	0.795	1.00
321_D	324_A	0.794	1.00
212_L	225_V	0.791	1.00
332_Y	336_E	0.790	1.00
90_L	145_Q	0.789	1.00
392_L	416_Y	0.788	1.00
301_A	362_A	0.784	1.00
415_D	451_L	0.784	1.00
234_N	258_V	0.783	1.00
77_M	288_M	0.782	1.00
261_A	380_V	0.781	1.00
313_L	316_A	0.780	1.00
69_K	438_P	0.778	1.00
366_L	405_M	0.778	1.00
133_L	193_D	0.777	1.00
366_L	399_S	0.775	1.00
249_A	390_V	0.773	1.00
23_V	26_A	0.772	1.00
31_L	43_Q	0.772	1.00
313_L	362_A	0.772	1.00
439_E	448_Q	0.772	1.00
132_L	176_W	0.771	1.00
300_W	303_K	0.771	1.00
335_G	339_P	0.771	1.00
45_P	92_P	0.770	1.00
322_E	363_R	0.769	1.00
153_K	230_G	0.768	1.00
258_V	290_V	0.768	1.00
26_A	421_D	0.767	1.00
103_Q	138_H	0.765	1.00
30_K	302_A	0.762	1.00
392_L	406_L	0.760	1.00
311_P	315_A	0.758	1.00
96_W	256_S	0.758	1.00
444_E	448_Q	0.756	1.00
451_L	457_P	0.754	1.00
42_E	100_R	0.752	1.00
29_E	51_A	0.752	1.00
375_D	469_R	0.749	1.00
468_R	471_T	0.748	1.00
84_D	90_L	0.748	1.00
251_L	373_L	0.747	1.00
310_V	317_A	0.747	1.00
251_L	257_G	0.742	1.00
83_L	164_F	0.742	1.00
294_A	369_V	0.741	1.00
177_L	182_R	0.737	1.00
187_V	191_A	0.736	1.00
50_Q	53_D	0.735	1.00
103_Q	137_R	0.735	1.00
47_Q	51_A	0.734	1.00
370_G	402_W	0.734	1.00
53_D	216_V	0.732	1.00
4_G	72_G	0.731	1.00
379_V	382_A	0.731	1.00
298_L	314_I	0.730	1.00
20_Q	448_Q	0.729	1.00
183_D	186_D	0.729	1.00
321_D	325_E	0.729	1.00
70_A	226_P	0.728	1.00
46_E	155_Y	0.728	1.00
82_L	90_L	0.727	1.00
467_P	471_T	0.727	1.00
17_L	419_G	0.726	1.00
166_S	202_L	0.724	1.00
463_A	468_R	0.723	1.00
9_T	95_L	0.723	1.00
326_P	468_R	0.720	1.00
314_I	401_Y	0.719	1.00
53_D	159_R	0.719	1.00
71_L	212_L	0.718	1.00
374_A	473_R	0.718	1.00
46_E	89_V	0.717	1.00
237_G	424_P	0.717	1.00
241_V	250_M	0.716	1.00
301_A	361_L	0.714	1.00
241_V	393_I	0.711	1.00
118_I	178_D	0.709	1.00
52_T	55_A	0.706	1.00
317_A	321_D	0.705	1.00
216_V	224_T	0.704	1.00
19_E	69_K	0.703	1.00
243_M	250_M	0.702	1.00
81_T	93_A	0.701	1.00
169_S	231_G	0.699	1.00
157_R	161_T	0.698	1.00
212_L	222_M	0.698	1.00
266_F	275_H	0.696	1.00
392_L	414_L	0.696	1.00
433_Q	437_N	0.696	1.00
434_I	441_S	0.696	1.00
397_A	403_R	0.695	1.00
301_A	305_T	0.694	1.00
178_D	183_D	0.692	1.00
85_A	145_Q	0.690	0.99
310_V	314_I	0.689	0.99
185_S	188_M	0.689	0.99
233_D	255_T	0.689	0.99
209_T	229_A	0.688	0.99
83_L	155_Y	0.687	0.99
7_L	51_A	0.687	0.99
190_Q	196_R	0.685	0.99
243_M	248_Q	0.685	0.99
12_V	31_L	0.685	0.99
87_Q	147_D	0.685	0.99
390_V	412_Q	0.685	0.99
289_S	376_G	0.685	0.99
456_L	459_A	0.683	0.99
84_D	147_D	0.683	0.99
216_V	221_G	0.682	0.99
388_Q	412_Q	0.682	0.99
106_T	344_Q	0.682	0.99
83_L	158_L	0.679	0.99
56_M	59_L	0.678	0.99
461_R	466_Q	0.677	0.99
345_A	348_V	0.677	0.99
94_I	100_R	0.675	0.99
211_A	214_P	0.674	0.99
308_S	311_P	0.672	0.99
326_P	367_E	0.671	0.99
155_Y	158_L	0.671	0.99
324_A	360_E	0.670	0.99
263_S	267_L	0.670	0.99
144_R	148_K	0.667	0.99
466_Q	469_R	0.664	0.99
404_Q	455_H	0.664	0.99
222_M	225_V	0.664	0.99
36_P	40_W	0.663	0.99
205_G	230_G	0.661	0.99
251_L	390_V	0.659	0.99
15_I	23_V	0.658	0.99
367_E	405_M	0.657	0.99
182_R	280_A	0.655	0.99
49_W	216_V	0.654	0.99
83_L	148_K	0.651	0.99
322_E	464_A	0.650	0.99
75_G	170_D	0.648	0.99
123_M	175_M	0.647	0.99
390_V	414_L	0.646	0.99
399_S	402_W	0.646	0.99
272_S	288_M	0.646	0.99
54_R	57_K	0.646	0.99
46_E	92_P	0.644	0.99
340_H	473_R	0.642	0.99
443_I	446_L	0.641	0.99
389_S	412_Q	0.639	0.99
133_L	143_F	0.639	0.99
80_A	128_T	0.636	0.99
430_R	434_I	0.636	0.99
430_R	448_Q	0.632	0.99
190_Q	195_S	0.632	0.99
464_A	468_R	0.631	0.99
108_L	192_C	0.630	0.99
314_I	317_A	0.629	0.99
119_T	188_M	0.627	0.99
445_L	449_L	0.627	0.99
17_L	425_A	0.624	0.99
257_G	406_L	0.620	0.99
403_R	416_Y	0.620	0.99
334_S	354_H	0.619	0.99
387_P	412_Q	0.619	0.99
76_Q	96_W	0.617	0.99
340_H	375_D	0.617	0.99
154_D	164_F	0.616	0.99
323_S	363_R	0.616	0.99
101_C	130_P	0.615	0.99
75_G	152_P	0.615	0.99
132_L	198_Q	0.615	0.99
325_E	355_Q	0.614	0.99
153_K	170_D	0.614	0.99
416_Y	452_E	0.613	0.99
188_M	192_C	0.613	0.99
176_W	199_M	0.613	0.99
332_Y	338_T	0.612	0.99
133_L	192_C	0.612	0.99
382_A	473_R	0.611	0.99
68_V	222_M	0.610	0.99
321_D	360_E	0.609	0.99
340_H	476_Y	0.608	0.99
81_T	89_V	0.607	0.99
307_L	312_A	0.607	0.99
470_E	473_R	0.603	0.99
291_M	376_G	0.603	0.99
169_S	205_G	0.603	0.99
441_S	447_P	0.602	0.99
94_I	135_V	0.601	0.99
329_F	368_G	0.599	0.99
363_R	405_M	0.599	0.99
434_I	439_E	0.596	0.99
208_I	436_A	0.596	0.99
260_F	286_H	0.595	0.99
204_E	280_A	0.595	0.99
330_L	476_Y	0.594	0.98
326_P	363_R	0.594	0.98
253_L	392_L	0.594	0.98
325_E	356_H	0.594	0.98
226_P	436_A	0.591	0.98
323_S	360_E	0.591	0.98
53_D	56_M	0.589	0.98
145_Q	148_K	0.588	0.98
23_V	419_G	0.588	0.98
242_G	446_L	0.588	0.98
346_K	350_F	0.587	0.98
190_Q	193_D	0.587	0.98
112_V	188_M	0.587	0.98
26_A	62_Q	0.587	0.98
240_G	423_G	0.582	0.98
463_A	466_Q	0.582	0.98
232_G	235_A	0.581	0.98
108_L	130_P	0.580	0.98
143_F	195_S	0.580	0.98
234_N	252_S	0.579	0.98
326_P	360_E	0.578	0.98
320_A	325_E	0.578	0.98
42_E	91_R	0.578	0.98
276_S	286_H	0.577	0.98
413_Q	457_P	0.577	0.98
46_E	49_W	0.575	0.98
434_I	437_N	0.575	0.98
143_F	193_D	0.575	0.98
320_A	363_R	0.574	0.98
411_G	459_A	0.573	0.98
323_S	327_V	0.573	0.98
174_T	184_W	0.573	0.98
127_F	173_G	0.572	0.98
143_F	147_D	0.571	0.98
320_A	324_A	0.571	0.98
71_L	227_V	0.569	0.98
367_E	371_Y	0.568	0.98
130_P	175_M	0.568	0.98
45_P	93_A	0.567	0.98
172_A	278_C	0.566	0.98
400_E	404_Q	0.565	0.98
369_V	402_W	0.565	0.98
452_E	457_P	0.564	0.98
216_V	222_M	0.564	0.98
206_S	435_A	0.564	0.98
330_L	348_V	0.563	0.98
194_L	199_M	0.562	0.98
136_Q	193_D	0.559	0.98
44_D	50_Q	0.558	0.98
290_V	337_R	0.557	0.98
205_G	231_G	0.557	0.98
121_N	127_F	0.557	0.98
16_L	65_L	0.557	0.98
88_R	145_Q	0.556	0.98
77_M	173_G	0.556	0.98
40_W	94_I	0.556	0.98
162_G	215_E	0.553	0.98
188_M	191_A	0.553	0.98
324_A	363_R	0.552	0.98
304_L	357_G	0.551	0.98
226_P	229_A	0.551	0.98
89_V	92_P	0.549	0.98
111_R	133_L	0.548	0.97
87_Q	148_K	0.547	0.97
102_A	125_P	0.547	0.97
79_G	95_L	0.546	0.97
299_D	310_V	0.546	0.97
248_Q	446_L	0.546	0.97
333_L	336_E	0.545	0.97
100_R	138_H	0.545	0.97
238_A	260_F	0.544	0.97
445_L	448_Q	0.543	0.97
279_H	282_P	0.543	0.97
314_I	366_L	0.542	0.97
201_A	207_E	0.542	0.97
336_E	342_N	0.542	0.97
331_P	335_G	0.541	0.97
51_A	54_R	0.541	0.97
324_A	367_E	0.540	0.97
35_R	41_S	0.539	0.97
163_E	203_Y	0.539	0.97
157_R	229_A	0.539	0.97
125_P	343_P	0.539	0.97
48_W	93_A	0.538	0.97
10_S	13_K	0.537	0.97
82_L	91_R	0.537	0.97
163_E	211_A	0.536	0.97
406_L	410_S	0.536	0.97
404_Q	407_A	0.535	0.97
397_A	416_Y	0.535	0.97
419_G	426_L	0.535	0.97
74_A	428_A	0.535	0.97
22_E	450_P	0.533	0.97
261_A	387_P	0.533	0.97
255_T	296_S	0.532	0.97
41_S	95_L	0.532	0.97
206_S	282_P	0.532	0.97
407_A	414_L	0.531	0.97
2_Y	69_K	0.531	0.97
239_V	430_R	0.530	0.97
326_P	471_T	0.530	0.97
425_A	428_A	0.530	0.97
342_N	345_A	0.530	0.97
40_W	100_R	0.526	0.97
327_V	361_L	0.525	0.97
238_A	278_C	0.525	0.97
28_T	421_D	0.525	0.97
466_Q	473_R	0.525	0.97
259_Y	376_G	0.523	0.97
57_K	60_G	0.522	0.97
331_P	368_G	0.521	0.97
154_D	200_P	0.520	0.97
248_Q	388_Q	0.519	0.97
206_S	434_I	0.519	0.97
168_M	205_G	0.518	0.96
251_L	259_Y	0.517	0.96
263_S	287_L	0.516	0.96
9_T	96_W	0.516	0.96
442_L	446_L	0.516	0.96
15_I	426_L	0.515	0.96
328_W	371_Y	0.514	0.96
249_A	377_M	0.514	0.96
78_H	256_S	0.514	0.96
418_T	451_L	0.514	0.96
443_I	447_P	0.511	0.96
150_L	158_L	0.511	0.96
22_E	418_T	0.510	0.96
233_D	395_G	0.510	0.96
169_S	235_A	0.509	0.96
144_R	147_D	0.508	0.96
151_L	170_D	0.506	0.96
239_V	279_H	0.506	0.96
80_A	135_V	0.506	0.96
405_M	468_R	0.506	0.96
252_S	393_I	0.505	0.96
302_A	310_V	0.505	0.96
411_G	461_R	0.505	0.96
242_G	449_L	0.505	0.96
257_G	291_M	0.504	0.96
175_M	192_C	0.504	0.96
119_T	185_S	0.504	0.96
180_A	183_D	0.504	0.96
371_Y	471_T	0.504	0.96
266_F	285_W	0.503	0.96
76_Q	232_G	0.503	0.96
250_M	260_F	0.502	0.96
373_L	406_L	0.502	0.96
323_S	468_R	0.500	0.96
213_L	224_T	0.500	0.96
318_Q	400_E	0.500	0.96

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2itmA	2	0.9814	100	0.099	Contact Map
3ll3A	2	0.9917	100	0.109	Contact Map
3ifrA	2	0.9855	100	0.129	Contact Map
3hz6A	1	0.9793	100	0.132	Contact Map
3qdkA	2	0.9959	100	0.141	Contact Map
3wxlA	2	0.9917	100	0.147	Contact Map
3g25A	3	0.9876	100	0.148	Contact Map
3h3nX	3	0.9876	100	0.149	Contact Map
3ezwA	3	0.9876	100	0.149	Contact Map
2d4wA	2	0.9855	100	0.15	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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