T1MK - ECOLI - GREMLIN Contacts

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T1MK - Type I restriction enzyme EcoKI M protein

UniProt:	P08957	Sequences: MNNNDLVAKLWKLCDNLRDGGVSYQNYVNELASLLFLKMCKETGQEAEYLPEGYRWDDLKSRIGQEQLQFYRKMLVHLGEDDKKLVQAVFHNVSTTITEPKQITALVSNMDSLDWYNGAHGKSRDDFGDMYEGLLQKNANETKSGAGQYFTPRPLIKTIIHLLKPQPREVVQDPAAGTAGFLIEADRYVKSQTNDLDDLDGDTQDFQIHRAFIGLELVPGTRRLALMNCLLHDIEGNLDHGGAIRLGNTLGSDGENLPKAHIVATNPPFGSAAGTNITRTFVHPTSNKQLCFMQHIIETLHPGGRAAVVVPDNVLFEGGKGTDIRRDLMDKCHLHTILRLPTGIFYAQGVKTNVLFFTKGTVANPNQDKNCTDDVWVYDLRTNMPSFGKRTPFTDEHLQPFERVYGEDPHGLSPRTEGEWSFNAEETEVADSEENKNTDQHLATSRWRKFSREWIRTAKSDSLDISWLKDKDSIDADSLPEPDVLAAEAMGELVQALSELDALMRELGASDEADLQRQLLEEAFGGVKE	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10458
Length:	529 (441)
Sequences:	6086 (4039)
Seq/√Len:	192.3

ECOLI - T1MK
BACSU - YEEA YTXK
HALSA - Q9HSR9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
326_R	330_D	5.667	1.00
159_I	307_A	4.297	1.00
300_L	306_A	4.002	1.00
323_D	326_R	3.923	1.00
261_H	301_H	3.891	1.00
293_M	310_V	3.451	1.00
399_Q	403_R	3.347	1.00
394_T	397_H	3.284	1.00
53_G	58_D	3.261	1.00
296_I	306_A	3.192	1.00
161_H	188_Y	2.927	1.00
478_S	481_E	2.920	1.00
375_V	435_N	2.826	1.00
433_E	437_N	2.792	1.00
244_I	249_T	2.733	1.00
436_K	440_Q	2.687	1.00
159_I	264_A	2.630	1.00
327_D	331_K	2.604	1.00
75_L	79_G	2.591	1.00
296_I	308_V	2.512	1.00
433_E	436_K	2.424	1.00
307_A	354_V	2.395	1.00
12_K	15_D	2.394	1.00
171_V	185_A	2.371	1.00
459_K	463_L	2.370	1.00
244_I	250_L	2.342	1.00
431_D	434_E	2.278	1.00
76_V	79_G	2.266	1.00
176_A	225_A	2.117	1.00
157_K	184_E	2.098	1.00
335_H	358_T	2.096	1.00
461_D	464_D	2.095	1.00
172_Q	299_T	2.068	1.00
307_A	356_F	2.035	1.00
432_S	440_Q	1.973	1.00
157_K	395_D	1.968	1.00
244_I	248_N	1.938	1.00
322_T	326_R	1.923	1.00
297_I	332_C	1.915	1.00
175_A	265_T	1.908	1.00
176_A	214_G	1.899	1.00
161_H	402_E	1.897	1.00
69_Q	73_K	1.885	1.00
297_I	328_L	1.879	1.00
396_E	399_Q	1.871	1.00
472_D	475_D	1.867	1.00
179_A	225_A	1.844	1.00
38_K	42_E	1.832	1.00
300_L	304_G	1.814	1.00
480_P	484_V	1.812	1.00
265_T	296_I	1.806	1.00
470_D	474_I	1.794	1.00
8_A	12_K	1.784	1.00
312_D	339_R	1.778	1.00
411_G	415_R	1.768	1.00
432_S	436_K	1.757	1.00
315_L	337_I	1.747	1.00
467_W	471_K	1.738	1.00
329_M	375_V	1.725	1.00
175_A	292_F	1.724	1.00
480_P	483_D	1.722	1.00
400_P	404_V	1.720	1.00
471_K	475_D	1.711	1.00
428_E	434_E	1.689	1.00
309_V	354_V	1.688	1.00
438_T	441_H	1.684	1.00
471_K	474_I	1.675	1.00
330_D	436_K	1.667	1.00
402_E	405_Y	1.666	1.00
248_N	251_G	1.659	1.00
380_L	401_F	1.645	1.00
270_G	273_A	1.638	1.00
469_K	472_D	1.618	1.00
445_S	449_K	1.604	1.00
410_H	415_R	1.592	1.00
163_L	262_I	1.574	1.00
443_A	446_R	1.556	1.00
403_R	407_E	1.553	1.00
157_K	161_H	1.553	1.00
476_A	483_D	1.549	1.00
473_S	477_D	1.537	1.00
71_Y	78_L	1.535	1.00
305_R	358_T	1.528	1.00
460_S	464_D	1.517	1.00
45_Q	57_D	1.512	1.00
148_Q	218_V	1.508	1.00
477_D	481_E	1.507	1.00
164_K	188_Y	1.495	1.00
238_L	244_I	1.492	1.00
443_A	447_W	1.490	1.00
74_M	77_H	1.488	1.00
462_S	466_S	1.483	1.00
302_P	359_K	1.481	1.00
297_I	333_H	1.474	1.00
216_E	221_T	1.473	1.00
247_G	252_S	1.467	1.00
109_N	112_S	1.466	1.00
464_D	467_W	1.460	1.00
397_H	400_P	1.450	1.00
464_D	468_L	1.443	1.00
330_D	440_Q	1.438	1.00
466_S	470_D	1.437	1.00
160_I	188_Y	1.432	1.00
184_E	187_R	1.429	1.00
9_K	112_S	1.418	1.00
411_G	414_P	1.418	1.00
71_Y	75_L	1.418	1.00
374_D	431_D	1.415	1.00
458_A	461_D	1.402	1.00
474_I	478_S	1.394	1.00
434_E	437_N	1.391	1.00
71_Y	79_G	1.385	1.00
12_K	109_N	1.355	1.00
85_L	88_A	1.354	1.00
158_T	162_L	1.347	1.00
26_N	29_N	1.344	1.00
343_G	349_G	1.341	1.00
442_L	447_W	1.339	1.00
169_E	262_I	1.333	1.00
476_A	479_L	1.330	1.00
216_E	222_R	1.329	1.00
458_A	464_D	1.318	1.00
459_K	467_W	1.317	1.00
450_F	454_W	1.316	1.00
475_D	478_S	1.311	1.00
400_P	403_R	1.310	1.00
478_S	482_P	1.304	1.00
174_P	265_T	1.298	1.00
426_E	430_A	1.284	1.00
156_I	181_F	1.279	1.00
481_E	485_L	1.279	1.00
479_L	482_P	1.275	1.00
328_L	333_H	1.274	1.00
332_C	361_T	1.273	1.00
164_K	406_G	1.272	1.00
60_K	111_D	1.269	1.00
385_P	392_P	1.267	1.00
57_D	61_S	1.258	1.00
51_P	54_Y	1.251	1.00
163_L	307_A	1.242	1.00
160_I	264_A	1.242	1.00
398_L	402_E	1.242	1.00
444_T	447_W	1.242	1.00
334_L	357_F	1.229	1.00
312_D	351_K	1.220	1.00
462_S	465_I	1.220	1.00
337_I	355_L	1.217	1.00
434_E	438_T	1.211	1.00
408_D	411_G	1.209	1.00
85_L	89_V	1.207	1.00
247_G	251_G	1.202	1.00
463_L	467_W	1.197	1.00
395_D	399_Q	1.193	1.00
270_G	275_T	1.193	1.00
444_T	448_R	1.192	1.00
66_E	70_F	1.190	1.00
383_N	400_P	1.184	1.00
332_C	373_D	1.179	1.00
58_D	61_S	1.173	1.00
467_W	470_D	1.173	1.00
465_I	468_L	1.173	1.00
213_I	260_A	1.173	1.00
52_E	55_R	1.171	1.00
461_D	465_I	1.169	1.00
67_Q	70_F	1.167	1.00
461_D	469_K	1.167	1.00
458_A	462_S	1.163	1.00
407_E	411_G	1.161	1.00
313_N	317_E	1.160	1.00
461_D	472_D	1.160	1.00
342_T	349_G	1.159	1.00
343_G	351_K	1.157	1.00
64_G	70_F	1.149	1.00
64_G	67_Q	1.144	1.00
336_T	356_F	1.140	1.00
246_L	249_T	1.131	1.00
312_D	316_F	1.127	1.00
90_F	93_V	1.127	1.00
189_V	210_R	1.122	1.00
444_T	449_K	1.121	1.00
342_T	351_K	1.110	1.00
383_N	397_H	1.107	1.00
455_I	458_A	1.106	1.00
338_L	356_F	1.105	1.00
270_G	288_K	1.105	1.00
440_Q	446_R	1.104	1.00
74_M	79_G	1.104	1.00
446_R	449_K	1.103	1.00
270_G	274_G	1.095	1.00
464_D	472_D	1.093	1.00
75_L	78_L	1.092	1.00
442_L	445_S	1.092	1.00
174_P	296_I	1.087	1.00
72_R	76_V	1.086	1.00
58_D	62_R	1.075	1.00
274_G	278_T	1.073	1.00
424_A	427_T	1.070	1.00
338_L	354_V	1.067	1.00
159_I	354_V	1.065	1.00
470_D	473_S	1.062	1.00
310_V	355_L	1.060	1.00
50_L	56_W	1.060	1.00
303_G	360_G	1.056	1.00
427_T	430_A	1.055	1.00
172_Q	249_T	1.053	1.00
442_L	448_R	1.053	1.00
39_M	43_T	1.051	1.00
52_E	58_D	1.050	1.00
160_I	185_A	1.049	1.00
247_G	250_L	1.048	1.00
464_D	471_K	1.045	1.00
404_V	411_G	1.040	1.00
460_S	463_L	1.038	1.00
164_K	192_Q	1.030	1.00
348_Q	351_K	1.028	1.00
66_E	69_Q	1.028	1.00
477_D	480_P	1.027	1.00
432_S	435_N	1.025	1.00
310_V	314_V	1.022	1.00
341_P	352_T	1.021	1.00
170_V	258_P	1.016	1.00
475_D	479_L	1.012	1.00
67_Q	75_L	1.012	1.00
313_N	351_K	1.008	1.00
461_D	468_L	1.007	1.00
468_L	472_D	1.001	1.00
447_W	455_I	1.001	1.00
305_R	335_H	0.999	1.00
262_I	305_R	0.997	1.00
171_V	189_V	0.996	1.00
86_V	90_F	0.994	0.99
310_V	353_N	0.991	0.99
458_A	472_D	0.991	0.99
443_A	448_R	0.991	0.99
49_Y	52_E	0.988	0.99
374_D	429_V	0.986	0.99
246_L	251_G	0.985	0.99
34_L	37_L	0.982	0.99
259_K	302_P	0.982	0.99
472_D	476_A	0.979	0.99
172_Q	260_A	0.979	0.99
446_R	453_E	0.975	0.99
156_I	180_G	0.969	0.99
455_I	459_K	0.968	0.99
60_K	107_V	0.967	0.99
458_A	469_K	0.962	0.99
461_D	471_K	0.962	0.99
476_A	480_P	0.959	0.99
271_S	278_T	0.959	0.99
172_Q	263_V	0.958	0.99
157_K	187_R	0.941	0.99
56_W	60_K	0.941	0.99
289_Q	311_P	0.939	0.99
479_L	483_D	0.938	0.99
11_W	14_C	0.937	0.99
104_T	108_S	0.935	0.99
443_A	454_W	0.934	0.99
474_I	477_D	0.931	0.99
169_E	261_H	0.929	0.99
376_W	380_L	0.927	0.99
428_E	431_D	0.926	0.99
404_V	414_P	0.925	0.99
271_S	275_T	0.923	0.99
23_S	28_V	0.922	0.99
454_W	461_D	0.921	0.99
275_T	278_T	0.916	0.99
5_D	9_K	0.913	0.99
29_N	220_G	0.913	0.99
464_D	475_D	0.907	0.99
376_W	379_D	0.903	0.99
460_S	468_L	0.901	0.99
62_R	70_F	0.895	0.99
445_S	448_R	0.894	0.99
83_K	86_V	0.893	0.99
410_H	428_E	0.892	0.99
399_Q	402_E	0.889	0.99
442_L	451_S	0.887	0.99
423_N	427_T	0.887	0.99
430_A	435_N	0.886	0.99
312_D	341_P	0.884	0.99
465_I	479_L	0.884	0.99
423_N	426_E	0.879	0.99
410_H	413_S	0.879	0.99
445_S	450_F	0.878	0.99
446_R	451_S	0.876	0.99
284_P	291_C	0.873	0.99
89_V	93_V	0.872	0.99
334_L	355_L	0.872	0.99
441_H	444_T	0.872	0.99
332_C	359_K	0.871	0.99
440_Q	447_W	0.871	0.99
334_L	337_I	0.871	0.99
312_D	348_Q	0.866	0.99
441_H	446_R	0.865	0.99
246_L	250_L	0.865	0.99
16_N	105_A	0.865	0.99
54_Y	77_H	0.864	0.99
229_C	238_L	0.860	0.99
84_K	90_F	0.859	0.99
407_E	410_H	0.856	0.98
77_H	80_E	0.854	0.98
269_F	352_T	0.852	0.98
265_T	308_V	0.851	0.98
266_N	345_F	0.849	0.98
447_W	451_S	0.849	0.98
438_T	447_W	0.848	0.98
37_L	41_K	0.847	0.98
16_N	109_N	0.846	0.98
375_V	378_Y	0.845	0.98
317_E	320_K	0.843	0.98
425_E	428_E	0.843	0.98
340_L	350_V	0.840	0.98
450_F	455_I	0.839	0.98
73_K	77_H	0.838	0.98
244_I	247_G	0.838	0.98
169_E	305_R	0.837	0.98
273_A	276_N	0.836	0.98
36_F	227_M	0.836	0.98
465_I	469_K	0.834	0.98
328_L	334_L	0.833	0.98
458_A	471_K	0.833	0.98
72_R	94_S	0.832	0.98
468_L	471_K	0.832	0.98
430_A	434_E	0.829	0.98
446_R	455_I	0.821	0.98
272_A	286_S	0.821	0.98
68_L	72_R	0.818	0.98
447_W	454_W	0.817	0.98
424_A	430_A	0.810	0.98
73_K	76_V	0.809	0.98
289_Q	310_V	0.808	0.98
472_D	482_P	0.807	0.98
448_R	453_E	0.807	0.98
440_Q	444_T	0.806	0.98
442_L	449_K	0.803	0.98
448_R	455_I	0.802	0.98
311_P	350_V	0.801	0.98
295_H	298_E	0.801	0.98
389_K	393_F	0.800	0.98
297_I	357_F	0.799	0.98
63_I	70_F	0.796	0.98
456_R	459_K	0.795	0.98
271_S	288_K	0.793	0.98
468_L	475_D	0.792	0.98
179_A	182_L	0.790	0.97
395_D	402_E	0.788	0.97
185_A	264_A	0.785	0.97
437_N	441_H	0.784	0.97
408_D	429_V	0.784	0.97
442_L	446_R	0.783	0.97
380_L	386_S	0.783	0.97
244_I	251_G	0.781	0.97
308_V	357_F	0.779	0.97
23_S	218_V	0.778	0.97
385_P	394_T	0.777	0.97
55_R	58_D	0.775	0.97
306_A	357_F	0.775	0.97
293_M	355_L	0.775	0.97
269_F	350_V	0.773	0.97
451_S	454_W	0.772	0.97
446_R	450_F	0.770	0.97
408_D	414_P	0.769	0.97
342_T	348_Q	0.769	0.97
340_L	344_I	0.769	0.97
187_R	232_H	0.765	0.97
57_D	60_K	0.764	0.97
426_E	429_V	0.761	0.97
448_R	452_R	0.760	0.97
435_N	438_T	0.759	0.97
387_F	392_P	0.758	0.97
388_G	392_P	0.758	0.97
96_T	99_E	0.757	0.97
322_T	439_D	0.757	0.97
188_Y	191_S	0.755	0.97
452_R	456_R	0.755	0.97
70_F	73_K	0.752	0.97
472_D	479_L	0.750	0.97
182_L	214_G	0.749	0.97
187_R	190_K	0.748	0.96
439_D	446_R	0.748	0.96
101_K	105_A	0.747	0.96
159_I	181_F	0.747	0.96
162_L	356_F	0.745	0.96
465_I	472_D	0.744	0.96
293_M	308_V	0.743	0.96
124_R	129_D	0.742	0.96
125_D	228_N	0.742	0.96
459_K	465_I	0.741	0.96
343_G	348_Q	0.740	0.96
186_D	212_F	0.738	0.96
408_D	413_S	0.734	0.96
70_F	74_M	0.732	0.96
271_S	274_G	0.731	0.96
314_V	355_L	0.731	0.96
436_K	439_D	0.730	0.96
105_A	109_N	0.729	0.96
425_E	430_A	0.728	0.96
458_A	465_I	0.727	0.96
430_A	433_E	0.726	0.96
473_S	476_A	0.724	0.96
314_V	353_N	0.723	0.96
427_T	431_D	0.723	0.96
344_I	348_Q	0.722	0.96
444_T	451_S	0.721	0.96
133_G	137_K	0.721	0.96
15_D	18_R	0.720	0.96
453_E	456_R	0.720	0.96
337_I	353_N	0.717	0.96
469_K	483_D	0.715	0.95
30_E	33_S	0.714	0.95
70_F	75_L	0.713	0.95
23_S	29_N	0.711	0.95
156_I	184_E	0.711	0.95
434_E	447_W	0.710	0.95
68_L	71_Y	0.709	0.95
294_Q	327_D	0.708	0.95
449_K	452_R	0.708	0.95
53_G	56_W	0.707	0.95
29_N	33_S	0.706	0.95
49_Y	53_G	0.705	0.95
55_R	60_K	0.705	0.95
153_R	180_G	0.705	0.95
170_V	211_A	0.704	0.95
452_R	455_I	0.703	0.95
162_L	338_L	0.702	0.95
28_V	32_A	0.702	0.95
336_T	405_Y	0.701	0.95
273_A	278_T	0.699	0.95
465_I	471_K	0.698	0.95
86_V	89_V	0.698	0.95
181_F	264_A	0.695	0.95
462_S	472_D	0.693	0.95
441_H	447_W	0.692	0.95
340_L	345_F	0.692	0.95
12_K	16_N	0.690	0.95
375_V	379_D	0.689	0.94
42_E	45_Q	0.688	0.94
261_H	303_G	0.688	0.94
294_Q	324_I	0.687	0.94
150_F	221_T	0.687	0.94
447_W	450_F	0.687	0.94
372_T	378_Y	0.687	0.94
441_H	445_S	0.685	0.94
339_R	351_K	0.684	0.94
437_N	440_Q	0.683	0.94
445_S	452_R	0.677	0.94
320_K	323_D	0.676	0.94
458_A	475_D	0.676	0.94
170_V	213_I	0.675	0.94
289_Q	313_N	0.675	0.94
170_V	261_H	0.674	0.94
154_P	392_P	0.673	0.94
23_S	144_S	0.673	0.94
469_K	480_P	0.672	0.94
460_S	478_S	0.672	0.94
448_R	454_W	0.671	0.94
334_L	375_V	0.669	0.94
161_H	399_Q	0.669	0.94
309_V	349_G	0.669	0.94
263_V	300_L	0.668	0.94
172_Q	215_L	0.665	0.93
423_N	429_V	0.665	0.93
415_R	427_T	0.664	0.93
176_A	179_A	0.663	0.93
444_T	455_I	0.660	0.93
41_K	44_G	0.657	0.93
312_D	342_T	0.656	0.93
443_A	453_E	0.656	0.93
397_H	404_V	0.655	0.93
79_G	82_D	0.654	0.93
50_L	54_Y	0.654	0.93
446_R	454_W	0.653	0.93
462_S	483_D	0.653	0.93
303_G	358_T	0.652	0.93
344_I	350_V	0.652	0.93
466_S	480_P	0.651	0.93
158_T	402_E	0.651	0.93
270_G	278_T	0.651	0.93
53_G	73_K	0.648	0.92
372_T	376_W	0.648	0.92
398_L	405_Y	0.648	0.92
444_T	454_W	0.647	0.92
447_W	453_E	0.646	0.92
313_N	348_Q	0.646	0.92
151_T	266_N	0.646	0.92
74_M	78_L	0.646	0.92
11_W	137_K	0.645	0.92
463_L	466_S	0.645	0.92
464_D	469_K	0.644	0.92
41_K	45_Q	0.643	0.92
312_D	350_V	0.642	0.92
33_S	36_F	0.642	0.92
460_S	466_S	0.641	0.92
466_S	469_K	0.641	0.92
456_R	460_S	0.641	0.92
284_P	294_Q	0.640	0.92
463_L	468_L	0.638	0.92
84_K	87_Q	0.638	0.92
33_S	44_G	0.636	0.92
406_G	410_H	0.636	0.92
85_L	90_F	0.631	0.91
430_A	440_Q	0.630	0.91
439_D	442_L	0.630	0.91
6_L	130_M	0.630	0.91
439_D	447_W	0.628	0.91
400_P	411_G	0.628	0.91
319_G	426_E	0.627	0.91
311_P	348_Q	0.626	0.91
425_E	429_V	0.626	0.91
68_L	74_M	0.625	0.91
382_T	386_S	0.621	0.91
383_N	387_F	0.621	0.91
377_V	380_L	0.620	0.91
36_F	41_K	0.620	0.91
170_V	301_H	0.620	0.91
29_N	32_A	0.619	0.91
311_P	351_K	0.618	0.91
78_L	82_D	0.617	0.91
272_A	291_C	0.617	0.91
155_L	344_I	0.617	0.91
444_T	450_F	0.615	0.90
221_T	224_L	0.615	0.90
53_G	57_D	0.613	0.90
297_I	359_K	0.612	0.90
478_S	483_D	0.610	0.90
435_N	441_H	0.609	0.90
10_L	130_M	0.609	0.90
445_S	455_I	0.608	0.90
294_Q	298_E	0.606	0.90
371_C	376_W	0.606	0.90
67_Q	78_L	0.605	0.90
59_L	62_R	0.604	0.90
11_W	18_R	0.604	0.90
63_I	66_E	0.599	0.89
340_L	352_T	0.595	0.89
5_D	8_A	0.593	0.89
90_F	94_S	0.592	0.89
443_A	449_K	0.592	0.89
25_Q	29_N	0.592	0.89
473_S	481_E	0.589	0.88
435_N	440_Q	0.589	0.88
380_L	389_K	0.589	0.88
340_L	348_Q	0.588	0.88
476_A	482_P	0.587	0.88
471_K	476_A	0.587	0.88
183_I	229_C	0.585	0.88
228_N	232_H	0.584	0.88
270_G	312_D	0.583	0.88
313_N	350_V	0.582	0.88
462_S	476_A	0.582	0.88
346_Y	350_V	0.582	0.88
449_K	453_E	0.582	0.88
395_D	398_L	0.581	0.88
469_K	478_S	0.581	0.88
259_K	301_H	0.579	0.88
153_R	184_E	0.578	0.87
13_L	106_L	0.577	0.87
273_A	286_S	0.576	0.87
478_S	485_L	0.575	0.87
342_T	350_V	0.574	0.87
59_L	107_V	0.573	0.87
443_A	458_A	0.572	0.87
33_S	41_K	0.571	0.87
70_F	78_L	0.569	0.87
481_E	484_V	0.568	0.87
311_P	352_T	0.568	0.87
448_R	451_S	0.568	0.87
26_N	96_T	0.567	0.86
435_N	439_D	0.567	0.86
65_Q	71_Y	0.566	0.86
451_S	455_I	0.566	0.86
455_I	463_L	0.566	0.86
335_H	356_F	0.564	0.86
439_D	444_T	0.563	0.86
56_W	71_Y	0.563	0.86
263_V	296_I	0.563	0.86
385_P	388_G	0.562	0.86
475_D	482_P	0.561	0.86
273_A	288_K	0.560	0.86
297_I	306_A	0.560	0.86
375_V	380_L	0.559	0.86
26_N	31_L	0.557	0.86
313_N	341_P	0.555	0.85
38_K	41_K	0.553	0.85
105_A	108_S	0.552	0.85
67_Q	71_Y	0.551	0.85
9_K	12_K	0.550	0.85
423_N	428_E	0.549	0.85
14_C	17_L	0.548	0.85
312_D	349_G	0.547	0.84
458_A	467_W	0.547	0.84
341_P	351_K	0.546	0.84
225_A	238_L	0.546	0.84
384_M	387_F	0.545	0.84
317_E	321_G	0.544	0.84
14_C	27_Y	0.544	0.84
342_T	352_T	0.544	0.84
7_V	346_Y	0.544	0.84
469_K	476_A	0.543	0.84
335_H	408_D	0.543	0.84
463_L	470_D	0.543	0.84
135_L	224_L	0.543	0.84
469_K	473_S	0.541	0.84
76_V	80_E	0.538	0.84
83_K	87_Q	0.538	0.84
272_A	275_T	0.538	0.84
313_N	329_M	0.537	0.83
461_D	475_D	0.535	0.83
409_P	415_R	0.534	0.83
91_H	94_S	0.533	0.83
294_Q	297_I	0.533	0.83
410_H	414_P	0.533	0.83
456_R	463_L	0.532	0.83
389_K	392_P	0.531	0.83
50_L	53_G	0.530	0.83
439_D	448_R	0.528	0.82
450_F	453_E	0.528	0.82
460_S	472_D	0.528	0.82
56_W	59_L	0.528	0.82
471_K	478_S	0.527	0.82
51_P	55_R	0.527	0.82
315_L	353_N	0.527	0.82
313_N	316_F	0.526	0.82
376_W	383_N	0.526	0.82
272_A	276_N	0.526	0.82
459_K	462_S	0.525	0.82
95_T	99_E	0.524	0.82
67_Q	74_M	0.523	0.82
406_G	409_P	0.522	0.82
406_G	439_D	0.521	0.82
136_Q	146_A	0.519	0.81
17_L	22_V	0.519	0.81
449_K	454_W	0.518	0.81
423_N	431_D	0.518	0.81
174_P	295_H	0.518	0.81
346_Y	349_G	0.518	0.81
339_R	353_N	0.517	0.81
343_G	352_T	0.516	0.81
71_Y	76_V	0.515	0.81
60_K	108_S	0.514	0.81
97_I	100_P	0.513	0.81
146_A	218_V	0.513	0.81
182_L	229_C	0.511	0.80
14_C	137_K	0.509	0.80
340_L	343_G	0.509	0.80
386_S	391_T	0.509	0.80
319_G	322_T	0.509	0.80
161_H	191_S	0.508	0.80
189_V	194_N	0.508	0.80
87_Q	93_V	0.507	0.80
387_F	390_R	0.507	0.80
14_C	18_R	0.506	0.80
465_I	480_P	0.506	0.80
287_N	314_V	0.506	0.80
344_I	349_G	0.504	0.79
441_H	449_K	0.504	0.79
294_Q	308_V	0.503	0.79
289_Q	314_V	0.503	0.79
16_N	38_K	0.503	0.79
438_T	444_T	0.503	0.79
460_S	471_K	0.502	0.79
400_P	405_Y	0.500	0.79

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2ar0A	1	0.8771	100	0.299	Contact Map
3lkdA	1	0.7618	100	0.354	Contact Map
3ufbA	1	0.7902	100	0.362	Contact Map
3khkA	1	0.7958	100	0.375	Contact Map
2okcA	1	0.7921	100	0.375	Contact Map
3s1sA	1	0.8904	100	0.564	Contact Map
2f8lA	1	0.5917	100	0.582	Contact Map
2ih2A	1	0.6068	100	0.695	Contact Map
3v97A	1	0.8185	99.9	0.774	Contact Map
3lduA	1	0.5879	99.8	0.802	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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