GREMLIN Database
T1RK - Type I restriction enzyme EcoKI R protein
UniProt: P08956 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG10459
Length: 1170 (903)
Sequences: 661 (482)
Seq/√Len: 16.1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
564_P569_D7.0351.00
286_T300_V4.9431.00
760_I763_I4.8541.00
759_A763_I4.7741.00
284_W302_F4.5381.00
759_A764_T4.3571.00
763_I769_K4.1511.00
764_T769_K4.0941.00
375_P380_T4.0351.00
185_L189_Q3.7871.00
377_C380_T3.7611.00
601_S604_R3.6381.00
759_A762_K3.6221.00
760_I764_T3.6011.00
376_F380_T3.5811.00
759_A769_K3.5080.99
189_Q192_T3.4910.99
760_I769_K3.4640.99
600_V603_Y3.4440.99
375_P381_N3.3060.99
600_V604_R3.3000.99
375_P379_S3.2730.99
762_K769_K3.2260.99
681_E684_N3.1560.99
418_E566_A3.0910.99
1059_K1063_E3.0020.98
185_L190_Q2.9820.98
190_Q193_E2.9610.98
373_K376_F2.9380.98
951_P954_S2.8870.98
376_F379_S2.8760.98
186_E190_Q2.8660.98
532_G535_D2.8450.98
705_P742_E2.8390.98
460_I484_M2.7350.97
380_T384_E2.7160.97
373_K380_T2.6760.96
466_E613_V2.6680.96
956_E962_P2.6400.96
962_P965_I2.6260.96
338_F341_E2.5980.96
727_T789_I2.5930.96
413_W422_M2.5890.96
1056_S1059_K2.5830.96
376_F381_N2.5790.96
206_Q209_E2.5710.96
183_A190_Q2.5490.95
380_T383_R2.5270.95
666_Y692_D2.5210.95
937_V941_G2.5190.95
185_L188_K2.5190.95
757_H760_I2.4910.95
958_F962_P2.4910.95
186_E189_Q2.4840.95
758_D763_I2.4630.94
373_K377_C2.4460.94
185_L191_E2.4420.94
214_L265_L2.4380.94
189_Q193_E2.4260.94
896_H907_I2.4200.94
377_C381_N2.3700.93
599_Y603_Y2.3380.93
926_R929_E2.3370.93
953_W958_F2.3200.92
338_F344_L2.3070.92
951_P955_A2.2880.92
942_F945_R2.2660.91
899_L906_I2.2620.91
913_N926_R2.2550.91
202_A279_K2.1920.90
484_M615_I2.1840.90
743_E746_A2.1720.89
376_F384_E2.1700.89
380_T394_G2.1700.89
362_S365_D2.1640.89
923_Q926_R2.1630.89
950_G955_A2.1420.89
598_D601_S2.1320.89
705_P743_E2.1230.88
188_K191_E2.1160.88
1059_K1064_T2.1020.88
592_Q595_S2.0840.87
899_L908_G2.0830.87
1012_D1016_Q2.0790.87
498_L547_A2.0780.87
961_L964_F2.0730.87
902_K905_R2.0580.87
207_L219_E2.0550.87
921_D925_R2.0520.86
904_Q907_I2.0500.86
485_M497_I2.0370.86
373_K378_Y2.0240.86
1060_A1063_E2.0090.85
741_V791_V2.0070.85
375_P378_Y1.9980.85
899_L907_I1.9800.84
598_D603_Y1.9770.84
183_A192_T1.9770.84
896_H906_I1.9740.84
903_L906_I1.9700.84
587_T590_E1.9670.84
940_N946_L1.9620.84
183_A191_E1.9520.84
340_R343_L1.9490.83
921_D924_V1.9240.83
945_R950_G1.9180.82
360_E413_W1.9100.82
1056_S1063_E1.8740.81
183_A189_Q1.8720.81
940_N944_S1.8590.80
185_L192_T1.8530.80
936_G945_R1.8470.80
466_E615_I1.8450.80
204_E208_A1.8360.79
295_G767_A1.8340.79
901_A904_Q1.8150.79
731_C740_V1.8070.78
378_Y381_N1.8050.78
899_L903_L1.7920.78
375_P383_R1.7850.77
783_K786_L1.7820.77
451_D640_T1.7730.77
300_V307_P1.7670.77
301_L414_H1.7580.76
763_I768_D1.7510.76
303_V308_I1.7500.76
337_G341_E1.7430.76
184_I191_E1.7420.76
186_E191_E1.7410.76
295_G333_C1.7380.75
944_S947_R1.7360.75
666_Y669_K1.7340.75
895_S899_L1.7330.75
945_R949_K1.7310.75
960_K965_I1.7300.75
650_Q848_Y1.7280.75
712_C740_V1.7190.75
901_A907_I1.7180.75
184_I188_K1.7170.75
689_D845_V1.6970.74
740_V744_L1.6910.73
940_N945_R1.6900.73
924_V946_L1.6780.73
896_H899_L1.6750.73
184_I189_Q1.6730.73
888_G891_F1.6670.72
917_S924_V1.6650.72
588_E591_L1.6590.72
1060_A1064_T1.6510.72
378_Y382_G1.6480.71
915_D926_R1.6480.71
757_H762_K1.6460.71
901_A906_I1.6420.71
911_T915_D1.6390.71
184_I190_Q1.6350.71
1056_S1060_A1.6200.70
901_A905_R1.6170.70
962_P967_R1.6160.70
1115_D1119_Q1.6150.70
183_A186_E1.6130.70
954_S958_F1.6060.69
381_N384_E1.5960.69
587_T595_S1.5940.69
921_D926_R1.5930.69
946_L950_G1.5890.69
379_S384_E1.5890.69
680_G683_I1.5880.68
1097_L1101_K1.5870.68
421_E450_E1.5870.68
376_F382_G1.5780.68
942_F946_L1.5740.68
543_K552_L1.5720.68
341_E344_L1.5700.68
941_G945_R1.5690.68
914_R918_E1.5670.67
926_R945_R1.5670.67
1059_K1062_K1.5630.67
757_H764_T1.5530.67
719_L789_I1.5500.67
896_H905_R1.5450.66
379_S394_G1.5360.66
902_K907_I1.5270.65
1053_E1056_S1.5160.65
940_N947_R1.5140.65
952_H955_A1.5140.65
1089_F1093_V1.5120.65
944_S948_E1.5090.64
375_P394_G1.5090.64
648_I830_L1.5030.64
888_G899_L1.5030.64
898_Q901_A1.5030.64
707_F811_L1.5000.64
382_G394_G1.4940.64
340_R344_L1.4890.63
913_N936_G1.4870.63
604_R608_D1.4850.63
375_P382_G1.4840.63
957_V962_P1.4840.63
1039_G1053_E1.4820.63
1066_N1069_I1.4800.63
303_V423_L1.4780.63
954_S962_P1.4680.62
961_L965_I1.4620.62
721_P724_S1.4590.62
338_F343_L1.4500.61
924_V929_E1.4430.61
1037_R1040_L1.4410.61
913_N917_S1.4400.61
765_G768_D1.4400.61
924_V930_L1.4340.60
894_H899_L1.4340.60
659_R990_E1.4320.60
599_Y602_A1.4310.60
480_T818_I1.4300.60
761_I764_T1.4300.60
924_V928_D1.4210.60
899_L904_Q1.4200.60
953_W956_E1.4190.59
913_N928_D1.4190.59
857_M860_V1.4120.59
882_K888_G1.4090.59
1094_D1122_K1.3980.58
377_C384_E1.3980.58
709_R746_A1.3960.58
758_D764_T1.3960.58
377_C400_V1.3950.58
384_E394_G1.3930.58
941_G944_S1.3910.58
204_E220_Q1.3890.58
200_L204_E1.3870.58
757_H769_K1.3840.58
589_G595_S1.3750.57
205_A213_E1.3740.57
186_E192_T1.3700.57
285_P296_F1.3680.57
381_N394_G1.3620.56
455_A634_Y1.3620.56
587_T591_L1.3590.56
1100_I1106_W1.3560.56
899_L905_R1.3470.55
421_E425_S1.3460.55
1042_E1046_W1.3430.55
1037_R1041_V1.3420.55
709_R743_E1.3400.55
926_R936_G1.3400.55
896_H904_Q1.3390.55
416_P1114_L1.3360.55
1090_E1122_K1.3350.55
758_D762_K1.3350.55
337_G344_L1.3270.54
365_D372_F1.3240.54
1047_F1056_S1.3140.53
956_E964_F1.3130.53
1043_L1047_F1.3110.53
759_A768_D1.3110.53
923_Q929_E1.3090.53
926_R946_L1.3080.53
905_R908_G1.3080.53
378_Y394_G1.3050.53
714_E717_N1.3030.53
372_F375_P1.3000.53
739_M742_E1.2980.53
224_A1015_V1.2980.53
373_K381_N1.2970.53
925_R929_E1.2900.52
954_S961_L1.2890.52
910_A913_N1.2890.52
590_E595_S1.2870.52
967_R970_K1.2870.52
1061_W1064_T1.2860.52
708_N743_E1.2820.52
327_S344_L1.2820.52
185_L193_E1.2780.51
1053_E1065_R1.2770.51
658_T711_V1.2750.51
915_D924_V1.2740.51
958_F961_L1.2710.51
760_I765_G1.2710.51
764_T767_A1.2700.51
705_P709_R1.2660.51
767_A781_F1.2660.51
648_I832_P1.2650.51
907_I913_N1.2650.51
740_V811_L1.2630.51
895_S906_I1.2630.51
946_L949_K1.2630.51
757_H763_I1.2620.50
731_C737_A1.2610.50
760_I768_D1.2590.50
375_P384_E1.2580.50
955_A962_P1.2580.50
423_L914_R1.2570.50
935_A945_R1.2560.50
585_E588_E1.2540.50
758_D769_K1.2480.50
600_V605_R1.2470.50
598_D602_A1.2470.50
1083_G1086_L1.2460.50
1039_G1042_E1.2460.50
443_L638_Y1.2440.49
898_Q905_R1.2440.49
895_S898_Q1.2360.49
941_G946_L1.2350.49
242_E246_R1.2330.49
597_L600_V1.2320.49
763_I767_A1.2310.49
923_Q946_L1.2300.49
935_A942_F1.2280.48
508_E775_Q1.2280.48
899_L902_K1.2260.48
939_F943_A1.2240.48
1070_A1120_A1.2230.48
374_I377_C1.2230.48
915_D918_E1.2200.48
913_N945_R1.2200.48
920_I924_V1.2190.48
759_A765_G1.2170.48
187_G191_E1.2140.48
376_F394_G1.2110.48
725_Q806_C1.2100.47
917_S926_R1.2100.47
534_T561_E1.2100.47
861_V864_P1.2090.47
903_L908_G1.2070.47
950_G953_W1.2060.47
763_I766_D1.2040.47
1042_E1045_E1.1990.47
376_F383_R1.1980.47
896_H908_G1.1970.47
614_K1064_T1.1950.47
434_F437_N1.1950.47
1108_S1120_A1.1940.47
975_I978_L1.1920.46
1051_H1059_K1.1840.46
473_T825_G1.1830.46
447_Y646_F1.1830.46
684_N1015_V1.1790.46
914_R924_V1.1730.45
781_F805_I1.1720.45
841_I1055_S1.1700.45
186_E193_E1.1660.45
764_T768_D1.1620.45
378_Y384_E1.1590.45
501_V507_G1.1560.44
898_Q906_I1.1560.44
914_R921_D1.1540.44
587_T596_Q1.1520.44
1101_K1121_L1.1520.44
432_Q435_A1.1510.44
889_R893_E1.1500.44
1013_S1017_R1.1460.44
549_V1007_F1.1430.44
936_G946_L1.1420.44
303_V419_L1.1350.43
915_D925_R1.1330.43
379_S383_R1.1310.43
737_A793_V1.1280.43
285_P294_Q1.1270.43
926_R942_F1.1240.43
308_I423_L1.1200.42
929_E936_G1.1200.42
949_K955_A1.1190.42
909_L912_F1.1180.42
916_R920_I1.1170.42
318_I322_A1.1170.42
762_K765_G1.1170.42
776_T779_T1.1130.42
465_Q633_V1.1120.42
945_R948_E1.1110.42
924_V927_L1.1080.42
378_Y414_H1.1070.42
1056_S1061_W1.1050.41
564_P696_A1.1040.41
898_Q904_Q1.1040.41
1056_S1064_T1.1030.41
960_K964_F1.1010.41
377_C383_R1.0970.41
916_R927_L1.0960.41
309_A334_F1.0920.41
378_Y383_R1.0900.41
372_F377_C1.0890.41
894_H906_I1.0880.40
587_T592_Q1.0880.40
1112_S1115_D1.0860.40
962_P968_L1.0860.40
473_T821_E1.0840.40
588_E595_S1.0820.40
1100_I1104_N1.0770.40
762_K768_D1.0770.40
915_D935_A1.0760.40
789_I806_C1.0760.40
1058_R1064_T1.0700.39
488_L645_G1.0690.39
914_R926_R1.0680.39
218_T986_D1.0670.39
374_I379_S1.0670.39
738_D742_E1.0650.39
921_D945_R1.0640.39
944_S950_G1.0630.39
705_P739_M1.0620.39
243_E544_I1.0620.39
761_I767_A1.0580.39
374_I380_T1.0580.39
1086_L1093_V1.0560.39
927_L1114_L1.0550.39
966_A970_K1.0550.39
334_F880_T1.0540.39
188_K192_T1.0530.39
892_A899_L1.0530.39
958_F964_F1.0530.39
238_L248_L1.0520.38
888_G903_L1.0510.38
913_N921_D1.0470.38
551_S824_K1.0460.38
408_K465_Q1.0460.38
1051_H1056_S1.0450.38
280_A301_L1.0400.38
373_K379_S1.0360.38
478_T510_A1.0360.38
337_G343_L1.0360.38
915_D945_R1.0350.38
948_E954_S1.0320.37
964_F969_E1.0320.37
490_Q500_L1.0320.37
915_D946_L1.0260.37
511_L546_V1.0230.37
372_F376_F1.0210.37
936_G942_F1.0210.37
603_Y607_L1.0210.37
1057_L1062_K1.0150.36
912_F926_R1.0140.36
1089_F1118_A1.0140.36
926_R930_L1.0130.36
745_R757_H1.0120.36
1059_K1066_N1.0070.36
257_G419_L1.0060.36
260_A301_L1.0030.36
929_E945_R1.0020.36
779_T1097_L1.0010.36
303_V420_L1.0000.36
484_M488_L0.9990.36
588_E592_Q0.9990.36
379_S382_G0.9970.36
635_R1001_Y0.9970.36
400_V733_T0.9960.35
572_V649_D0.9950.35
1048_D1051_H0.9950.35
695_V793_V0.9950.35
452_A480_T0.9930.35
221_E713_N0.9900.35
1068_D1072_R0.9880.35
756_E759_A0.9880.35
1007_F1015_V0.9880.35
898_Q907_I0.9810.35
308_I419_L0.9760.34
198_A306_K0.9750.34
450_E454_R0.9730.34
253_L727_T0.9730.34
982_P988_D0.9720.34
280_A299_Y0.9710.34
871_L879_E0.9710.34
413_W444_G0.9710.34
598_D604_R0.9700.34
274_E279_K0.9690.34
596_Q599_Y0.9680.34
870_T874_E0.9680.34
215_A253_L0.9670.34
960_K963_G0.9670.34
589_G592_Q0.9660.34
258_W569_D0.9640.34
941_G948_E0.9640.34
206_Q211_N0.9620.34
915_D921_D0.9570.33
1047_F1052_F0.9560.33
761_I765_G0.9540.33
921_D946_L0.9540.33
941_G947_R0.9500.33
225_Y310_V0.9480.33
900_V904_Q0.9480.33
656_I714_E0.9480.33
271_A274_E0.9460.33
954_S957_V0.9440.33
1036_T1039_G0.9440.33
616_A730_F0.9430.33
183_A193_E0.9410.33
214_L219_E0.9400.33
521_G524_F0.9400.33
948_E952_H0.9370.32
680_G691_Q0.9360.32
221_E225_Y0.9360.32
915_D942_F0.9350.32
278_N699_N0.9340.32
549_V572_V0.9340.32
1107_S1120_A0.9330.32
911_T926_R0.9330.32
932_Q936_G0.9320.32
364_Q808_I0.9310.32
435_A842_F0.9300.32
466_E484_M0.9280.32
680_G684_N0.9270.32
251_A255_K0.9250.32
338_F342_T0.9250.32
807_N840_K0.9230.32
695_V732_V0.9220.32
545_H568_Y0.9220.32
479_R483_A0.9210.32
1024_A1027_A0.9200.32
867_E871_L0.9190.31
902_K906_I0.9180.31
500_L974_D0.9160.31
383_R394_G0.9160.31
458_K462_K0.9150.31
586_Q591_L0.9110.31
1106_W1126_V0.9110.31
956_E965_I0.9100.31
932_Q945_R0.9090.31
219_E222_R0.9090.31
673_V679_Q0.9040.31
720_D748_F0.9010.31
904_Q908_G0.9000.31
729_V789_I0.8980.30
1093_V1118_A0.8980.30
948_E951_P0.8960.30
1107_S1124_K0.8960.30
1053_E1061_W0.8950.30
939_F945_R0.8950.30
306_K498_L0.8940.30
183_A187_G0.8920.30
184_I192_T0.8900.30
931_C934_A0.8900.30
447_Y505_S0.8900.30
1057_L1060_A0.8880.30
190_Q202_A0.8860.30
464_Q467_I0.8840.30
890_S898_Q0.8840.30
702_L711_V0.8780.29
355_A740_V0.8770.29
915_D944_S0.8760.29
1090_E1106_W0.8760.29
1052_F1060_A0.8760.29
204_E219_E0.8750.29
511_L515_E0.8730.29
933_D943_A0.8730.29
949_K953_W0.8730.29
425_S490_Q0.8720.29
872_V876_T0.8720.29
802_I805_I0.8710.29
1070_A1121_L0.8710.29
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514_F517_T0.5710.17
397_Y731_C0.5700.17
1098_T1102_G0.5700.17
544_I1029_I0.5690.17
500_L1035_L0.5690.17
292_G497_I0.5690.17
439_G1100_I0.5680.17
455_A633_V0.5680.17
343_L413_W0.5680.17
937_V940_N0.5680.17
947_R969_E0.5670.17
481_A844_C0.5670.17
335_D530_I0.5670.17
272_R423_L0.5660.17
410_L535_D0.5660.17
802_I934_A0.5650.17
804_S990_E0.5650.17
995_K999_G0.5640.17
352_V591_L0.5640.17
720_D723_G0.5640.17
585_E591_L0.5640.17
378_Y446_R0.5630.17
700_R778_I0.5630.17
301_L416_P0.5630.17
931_C937_V0.5630.17
266_R594_R0.5620.17
847_I851_L0.5620.17
535_D589_G0.5620.17
718_Y854_V0.5620.17
1085_A1117_L0.5610.17
483_A580_Y0.5610.17
899_L1077_I0.5600.17
309_A342_T0.5590.17
914_R946_L0.5590.17
930_L939_F0.5580.17
1086_L1121_L0.5580.17
911_T921_D0.5580.17
954_S959_N0.5580.17
923_Q936_G0.5570.17
896_H940_N0.5570.17
323_R563_M0.5570.17
622_A1073_L0.5570.17
989_D1035_L0.5560.16
638_Y649_D0.5560.16
595_S599_Y0.5560.16
593_F597_L0.5560.16
327_S808_I0.5560.16
210_K213_E0.5550.16
915_D920_I0.5550.16
1095_H1099_R0.5540.16
273_P664_G0.5540.16
460_I615_I0.5540.16
1073_L1093_V0.5540.16
467_I505_S0.5540.16
489_I522_D0.5530.16
421_E487_R0.5520.16
800_V847_I0.5520.16
668_S673_V0.5520.16
922_K938_N0.5510.16
663_E742_E0.5490.16
245_S248_L0.5490.16
706_A710_A0.5490.16
913_N924_V0.5480.16
216_K713_N0.5480.16
490_Q1077_I0.5480.16
414_H644_D0.5470.16
394_G423_L0.5470.16
864_P871_L0.5470.16
201_A205_A0.5460.16
675_R681_E0.5460.16
590_E593_F0.5460.16
1078_R1092_R0.5460.16
295_G737_A0.5450.16
255_K591_L0.5450.16
535_D906_I0.5450.16
1098_T1105_D0.5450.16
1033_R1051_H0.5450.16
761_I766_D0.5440.16
248_L1115_D0.5440.16
253_L737_A0.5440.16
505_S830_L0.5440.16
924_V933_D0.5440.16
729_V740_V0.5430.16
1073_L1113_W0.5430.16
955_A958_F0.5430.16
1035_L1048_D0.5430.16
417_E729_V0.5430.16
821_E1124_K0.5420.16
846_D854_V0.5420.16
231_D235_K0.5420.16
615_I879_E0.5410.16
311_V1078_R0.5410.16
815_R937_V0.5410.16
762_K766_D0.5400.16
916_R929_E0.5400.16
317_N323_R0.5400.16
207_L210_K0.5400.16
615_I1112_S0.5390.16
684_N855_D0.5380.16
1078_R1096_A0.5370.16
446_R1083_G0.5370.16
192_T195_Q0.5370.16
952_H956_E0.5360.16
741_V745_R0.5360.16
587_T600_V0.5350.16
1037_R1046_W0.5350.16
981_A991_V0.5350.16
351_E409_A0.5350.16
442_E566_A0.5340.16
972_K979_N0.5340.16
665_V668_S0.5340.16
895_S901_A0.5340.16
983_I991_V0.5340.16
548_T726_K0.5340.16
718_Y751_K0.5340.16
953_W959_N0.5340.16
644_D855_D0.5330.16
933_D939_F0.5330.16
1072_R1103_E0.5330.16
1035_L1040_L0.5330.16
198_A711_V0.5320.16
711_V980_D0.5320.16
418_E451_D0.5310.16
986_D1098_T0.5310.16
1069_I1076_H0.5310.16
573_V1071_A0.5300.16
258_W664_G0.5300.16
984_F988_D0.5300.16
684_N754_Q0.5290.16
361_T365_D0.5290.16
871_L877_D0.5290.16
266_R308_I0.5280.16
246_R250_D0.5280.16
1027_A1031_R0.5270.16
966_A972_K0.5270.16
203_L467_I0.5270.16
1020_N1028_V0.5270.16
785_R788_N0.5260.16
555_R664_G0.5250.16
865_K1017_R0.5250.16
490_Q493_R0.5250.16
969_E1038_K0.5240.15
988_D991_V0.5240.15
547_A1077_I0.5240.15
1085_A1118_A0.5230.15
1033_R1039_G0.5220.15
587_T599_Y0.5210.15
266_R271_A0.5210.15
702_L738_D0.5200.15
841_I1047_F0.5200.15
909_L915_D0.5200.15
1051_H1064_T0.5200.15
857_M994_V0.5190.15
207_L226_H0.5190.15
640_T677_S0.5190.15
482_I616_A0.5190.15
279_K991_V0.5190.15
258_W273_P0.5180.15
582_L600_V0.5180.15
898_Q903_L0.5180.15
413_W975_I0.5180.15
654_I994_V0.5180.15
320_V416_P0.5180.15
572_V668_S0.5180.15
192_T309_A0.5180.15
591_L849_S0.5180.15
984_F1073_L0.5180.15
752_Y875_I0.5170.15
915_D928_D0.5170.15
254_R1028_V0.5170.15
933_D938_N0.5170.15
258_W498_L0.5170.15
1101_K1109_E0.5160.15
266_R274_E0.5160.15
1023_P1086_L0.5160.15
812_R824_K0.5160.15
737_A802_I0.5160.15
921_D934_A0.5150.15
272_R594_R0.5150.15
755_L781_F0.5140.15
208_A417_E0.5140.15
774_V844_C0.5140.15
676_I737_A0.5140.15
931_C945_R0.5130.15
1007_F1011_F0.5130.15
934_A1119_Q0.5130.15
188_K193_E0.5130.15
291_T410_L0.5130.15
1038_K1051_H0.5130.15
332_K742_E0.5130.15
1014_L1018_S0.5120.15
472_A797_T0.5120.15
1035_L1047_F0.5120.15
479_R576_A0.5110.15
359_Y407_S0.5110.15
973_T1002_D0.5110.15
465_Q975_I0.5110.15
579_G616_A0.5110.15
1089_F1101_K0.5110.15
720_D1062_K0.5110.15
241_S480_T0.5110.15
995_K1001_Y0.5100.15
889_R902_K0.5100.15
337_G488_L0.5100.15
592_Q597_L0.5100.15
821_E825_G0.5100.15
714_E718_Y0.5090.15
589_G594_R0.5090.15
550_Q860_V0.5090.15
416_P721_P0.5090.15
196_T210_K0.5090.15
254_R300_V0.5080.15
308_I500_L0.5080.15
309_A340_R0.5070.15
526_S533_L0.5070.15
246_R273_P0.5070.15
383_R579_G0.5070.15
996_S1001_Y0.5060.15
286_T295_G0.5060.15
497_I901_A0.5060.15
690_D694_E0.5060.15
705_P732_V0.5060.15
330_Y625_T0.5050.15
359_Y465_Q0.5050.15
731_C1072_R0.5050.15
1103_E1120_A0.5050.15
470_A797_T0.5040.15
319_D538_P0.5040.15
534_T715_L0.5040.15
363_W413_W0.5040.15
1078_R1081_A0.5030.15
516_D1115_D0.5030.15
913_N918_E0.5030.15
924_V943_A0.5030.15
249_I737_A0.5020.15
964_F968_L0.5020.15
927_L947_R0.5020.15
691_Q790_V0.5020.15
512_G515_E0.5020.15
222_R228_E0.5020.15
589_G950_G0.5020.15
589_G598_D0.5020.15
566_A842_F0.5010.15
715_L729_V0.5010.15
454_R663_E0.5010.15
647_L828_T0.5010.15
758_D768_D0.5010.15
889_R899_L0.5000.15
524_F528_F0.5000.15
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2w00A 1 0.6436 100 0.708 Contact Map
3h1tA 1 0.4188 100 0.759 Contact Map
2ocaA 1 0.4085 100 0.879 Contact Map
2fwrA 1 0.3496 100 0.891 Contact Map
4zcfC 1 0.4043 100 0.892 Contact Map
1z63A 1 0.3393 100 0.9 Contact Map
1z3iX 4 0.4462 100 0.903 Contact Map
1wp9A 1 0.3248 100 0.904 Contact Map
3oiyA 1 0.3162 100 0.905 Contact Map
1fuuA 2 0.3171 100 0.905 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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