GREMLIN Database
PT1 - Phosphoenolpyruvate-protein phosphotransferase
UniProt: P08839 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG10789
Length: 575 (521)
Sequences: 6070 (3545)
Seq/√Len: 155.3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
486_K490_D5.2281.00
400_R445_E5.1741.00
178_G220_L5.1571.00
493_H521_D3.6041.00
314_F383_F3.0731.00
436_A484_L3.0481.00
371_R408_I3.0201.00
318_K383_F2.9891.00
492_S499_T2.9031.00
324_C329_V2.8751.00
387_R425_E2.7971.00
357_W365_D2.7441.00
44_L90_I2.7261.00
321_A386_L2.6861.00
155_E177_L2.6651.00
501_M520_L2.5871.00
460_T484_L2.5621.00
232_T235_V2.5581.00
403_R445_E2.5341.00
439_A491_A2.5211.00
377_I386_L2.4551.00
318_K322_E2.4491.00
444_K495_E2.4081.00
437_T484_L2.3821.00
414_R420_F2.3781.00
371_R405_E2.3541.00
469_M473_L2.3501.00
414_R422_E2.3441.00
40_V94_K2.2901.00
390_F402_L2.2701.00
440_R494_A2.2641.00
541_N544_D2.2441.00
42_R101_D2.2271.00
360_I393_I2.1881.00
16_A218_L2.1771.00
143_G154_D2.1601.00
53_Q140_N2.1521.00
282_E286_R2.1391.00
488_V499_T2.1371.00
202_I222_A2.1061.00
390_F406_I2.0901.00
43_F89_I2.0781.00
360_I402_L2.0651.00
212_V229_V2.0471.00
264_L541_N2.0391.00
333_T390_F2.0341.00
374_L406_I2.0321.00
100_A265_D2.0191.00
284_A289_A2.0151.00
208_V212_V2.0121.00
483_N491_A2.0071.00
512_T533_I1.9901.00
269_V516_L1.9901.00
328_A387_R1.9781.00
309_T312_E1.9731.00
320_V329_V1.9451.00
470_I473_L1.9221.00
50_A140_N1.9071.00
285_E327_Q1.8941.00
213_K216_D1.8801.00
363_A370_L1.8551.00
51_S81_E1.8501.00
501_M515_L1.8461.00
157_I218_L1.8361.00
93_I100_A1.8361.00
304_R312_E1.8301.00
399_V446_V1.8241.00
267_H542_F1.8201.00
273_A289_A1.8181.00
394_I432_T1.8101.00
16_A212_V1.8091.00
331_V377_I1.7861.00
430_V435_A1.7841.00
292_V324_C1.7831.00
403_R407_E1.7801.00
401_A404_K1.7741.00
87_Q91_A1.7701.00
161_A183_A1.7631.00
440_R483_N1.7621.00
161_A182_D1.7441.00
487_Q491_A1.7441.00
180_I220_L1.7041.00
371_R412_E1.6991.00
438_I441_H1.6981.00
159_V218_L1.6951.00
520_L523_F1.6871.00
99_T102_A1.6791.00
273_A284_A1.6751.00
338_G354_F1.6721.00
259_L538_R1.6671.00
451_I485_I1.6661.00
217_Y236_I1.6631.00
105_H109_E1.6581.00
440_R491_A1.6571.00
35_Q38_Q1.6531.00
216_D230_N1.6461.00
108_I134_G1.6341.00
138_L212_V1.6311.00
430_V488_V1.6221.00
428_V442_L1.6091.00
513_L540_T1.6021.00
443_A449_F1.6001.00
500_G522_E1.5981.00
333_T363_A1.5971.00
441_H483_N1.5961.00
267_H521_D1.5921.00
489_I499_T1.5841.00
37_D94_K1.5831.00
390_F403_R1.5811.00
432_T459_Y1.5801.00
157_I178_G1.5761.00
507_G525_M1.5751.00
451_I520_L1.5531.00
513_L543_E1.5441.00
443_A497_K1.5431.00
180_I227_V1.5401.00
490_D494_A1.5361.00
405_E408_I1.5291.00
104_A137_L1.5241.00
438_I442_L1.5111.00
295_Y320_V1.5041.00
182_D209_T1.4831.00
261_A534_K1.4731.00
461_L481_V1.4701.00
330_I387_R1.4541.00
40_V90_I1.4501.00
364_M401_A1.4481.00
90_I94_K1.4481.00
321_A377_I1.4471.00
370_L402_L1.4461.00
113_S116_E1.4391.00
270_E290_E1.4221.00
202_I227_V1.4191.00
375_R416_E1.4191.00
305_D308_P1.4151.00
514_L518_M1.4101.00
330_I500_G1.4091.00
425_E498_W1.4081.00
256_L538_R1.4081.00
311_E315_A1.4061.00
300_L316_A1.4061.00
396_V445_E1.3991.00
469_M472_H1.3981.00
485_I518_M1.3971.00
281_V285_E1.3961.00
271_V537_I1.3861.00
182_D205_T1.3701.00
271_V534_K1.3681.00
439_A449_F1.3671.00
512_T537_I1.3581.00
159_V180_I1.3571.00
180_I205_T1.3501.00
310_E379_R1.3461.00
404_K408_I1.3431.00
271_V530_I1.3391.00
116_E131_R1.3361.00
41_E45_S1.3301.00
486_K518_M1.3281.00
435_A442_L1.3251.00
217_Y231_P1.3211.00
314_F379_R1.3161.00
94_K258_D1.3121.00
290_E327_Q1.3101.00
39_E42_R1.3061.00
43_F47_R1.3021.00
378_L406_I1.2991.00
474_Y479_P1.2941.00
485_I520_L1.2871.00
16_A159_V1.2801.00
451_I488_V1.2761.00
483_N487_Q1.2741.00
92_L106_E1.2741.00
428_V446_V1.2731.00
330_I498_W1.2731.00
56_T60_K1.2681.00
112_A116_E1.2661.00
289_A530_I1.2651.00
39_E100_A1.2651.00
52_A55_E1.2591.00
53_Q56_T1.2351.00
222_A226_Q1.2351.00
157_I220_L1.2321.00
365_D469_M1.2281.00
179_F194_A1.2251.00
394_I434_A1.2221.00
400_R403_R1.2181.00
513_L517_G1.2171.00
6_L54_L1.2101.00
154_D175_K1.2031.00
414_R421_D1.2011.00
145_K214_N1.1791.00
132_D166_S1.1761.00
281_V323_A1.1731.00
489_I520_L1.1681.00
285_E323_A1.1621.00
440_R495_E1.1591.00
272_C291_G1.1581.00
380_A386_L1.1581.00
116_E120_D1.1541.00
326_S385_K1.1521.00
42_R45_S1.1501.00
413_L416_E1.1491.00
357_W469_M1.1491.00
52_A56_T1.1481.00
282_E323_A1.1481.00
48_A52_A1.1421.00
438_I483_N1.1411.00
278_V316_A1.1381.00
403_R447_D1.1361.00
432_T462_A1.1341.00
408_I412_E1.1321.00
491_A494_A1.1311.00
115_L118_L1.1281.00
483_N486_K1.1281.00
389_M450_S1.1231.00
216_D229_V1.1201.00
118_L123_L1.1161.00
406_I426_I1.1151.00
207_S211_Q1.1131.00
505_L511_A1.1131.00
396_V400_R1.1131.00
489_I523_F1.1121.00
306_A309_T1.1091.00
377_I388_I1.1070.99
390_F426_I1.1070.99
407_E426_I1.1040.99
319_A323_A1.1040.99
91_A95_D1.1020.99
234_E238_K1.0980.99
254_A257_K1.0940.99
461_L478_S1.0900.99
262_I268_Q1.0900.99
350_E467_N1.0890.99
281_V284_A1.0880.99
476_P479_P1.0870.99
460_T481_V1.0770.99
314_F318_K1.0740.99
273_A530_I1.0690.99
13_F219_I1.0680.99
283_G286_R1.0580.99
381_S421_D1.0570.99
261_A290_E1.0520.99
310_E372_D1.0520.99
98_M106_E1.0490.99
112_A131_R1.0460.99
221_D224_N1.0440.99
267_H290_E1.0440.99
516_L537_I1.0420.99
153_Q156_V1.0390.99
102_A106_E1.0360.99
15_K154_D1.0330.99
223_V226_Q1.0320.99
54_L58_K1.0310.99
148_D151_A1.0290.99
252_E255_K1.0270.99
434_A480_S1.0260.99
182_D210_S1.0240.99
271_V523_F1.0210.99
155_E175_K1.0150.99
485_I488_V1.0150.99
68_E71_A1.0130.99
116_E119_D1.0120.99
218_L227_V1.0100.99
449_F492_S1.0100.99
221_D226_Q1.0070.99
182_D207_S1.0060.99
55_E77_I1.0050.99
403_R426_I1.0020.99
260_P268_Q0.9960.99
491_A495_E0.9950.99
202_I220_L0.9910.99
49_K140_N0.9900.99
10_G17_L0.9890.99
268_Q290_E0.9880.99
375_R412_E0.9880.99
475_Q478_S0.9850.99
333_T388_I0.9830.99
55_E59_T0.9830.99
379_R413_L0.9820.99
222_A225_N0.9810.99
58_K74_E0.9770.99
168_T197_L0.9750.99
487_Q490_D0.9640.99
453_T501_M0.9640.99
535_K539_N0.9640.99
152_I156_V0.9630.99
54_L77_I0.9610.99
305_D309_T0.9590.99
272_C522_E0.9570.99
374_L378_L0.9560.99
400_R404_K0.9500.98
104_A266_G0.9480.98
263_T267_H0.9460.98
219_I228_Y0.9450.98
310_E375_R0.9440.98
390_F399_V0.9420.98
525_M533_I0.9420.98
258_D288_G0.9410.98
507_G529_S0.9400.98
80_L137_L0.9400.98
153_Q175_K0.9370.98
388_I406_I0.9360.98
492_S497_K0.9340.98
127_A131_R0.9330.98
56_T59_T0.9320.98
385_K425_E0.9270.98
428_V435_A0.9250.98
101_D142_L0.9220.98
138_L142_L0.9180.98
367_R401_A0.9180.98
122_Y126_R0.9170.98
437_T487_Q0.9120.98
311_E379_R0.9120.98
119_D124_K0.9120.98
117_E120_D0.9100.98
212_V218_L0.9090.98
13_F217_Y0.9050.98
398_E473_L0.9030.98
357_W470_I0.9020.98
477_M511_A0.9010.98
14_G177_L0.9000.98
59_T62_G0.9000.98
99_T103_A0.8950.98
397_E400_R0.8940.98
401_A405_E0.8930.98
268_Q516_L0.8910.98
135_K138_L0.8900.98
307_L310_E0.8900.98
279_R303_D0.8860.98
421_D424_I0.8850.98
98_M102_A0.8840.98
441_H444_K0.8840.98
307_L345_M0.8830.97
439_A488_V0.8820.97
442_L449_F0.8820.97
437_T483_N0.8820.97
467_N470_I0.8790.97
415_D421_D0.8780.97
367_R408_I0.8760.97
355_L459_Y0.8740.97
290_E534_K0.8730.97
252_E535_K0.8720.97
88_E107_V0.8710.97
41_E44_L0.8650.97
264_L267_H0.8640.97
485_I515_L0.8630.97
107_V259_L0.8600.97
536_I539_N0.8600.97
486_K517_G0.8580.97
101_D266_G0.8580.97
457_T481_V0.8580.97
145_K149_L0.8560.97
378_L413_L0.8520.97
370_L405_E0.8480.97
89_I104_A0.8480.97
92_L97_H0.8460.97
307_L344_Y0.8430.97
61_A66_G0.8420.97
437_T460_T0.8420.97
207_S210_S0.8390.97
279_R319_A0.8350.96
333_T377_I0.8340.96
13_F236_I0.8340.96
285_E325_G0.8310.96
498_W522_E0.8290.96
357_W362_I0.8280.96
121_E125_E0.8280.96
120_D123_L0.8270.96
351_E466_G0.8260.96
336_I342_L0.8250.96
92_L110_G0.8230.96
474_Y477_M0.8210.96
15_K155_E0.8200.96
482_L514_L0.8180.96
414_R417_G0.8170.96
439_A443_A0.8160.96
272_C498_W0.8150.96
277_T280_D0.8130.96
436_A460_T0.8130.96
31_I97_H0.8120.96
261_A531_P0.8120.96
402_L426_I0.8100.96
40_V44_L0.8050.96
182_D208_V0.8040.96
43_F93_I0.8040.96
375_R379_R0.8030.96
360_I390_F0.8020.96
44_L48_A0.7990.95
60_K64_T0.7980.95
29_K99_T0.7950.95
200_P308_P0.7940.95
38_Q41_E0.7930.95
49_K52_A0.7920.95
513_L536_I0.7890.95
291_G328_A0.7870.95
55_E58_K0.7860.95
272_C387_R0.7850.95
412_E415_D0.7850.95
152_I155_E0.7840.95
281_V324_C0.7840.95
22_D46_G0.7820.95
137_L140_N0.7820.95
430_V442_L0.7820.95
162_D190_T0.7820.95
396_V442_L0.7810.95
88_E92_L0.7810.95
48_A51_S0.7810.95
489_I493_H0.7810.95
282_E319_A0.7800.95
53_Q136_R0.7800.95
285_E324_C0.7790.95
11_I219_I0.7790.95
441_H479_P0.7790.95
136_R140_N0.7780.95
399_V428_V0.7770.95
370_L374_L0.7770.95
42_R141_I0.7760.95
109_E113_S0.7760.95
133_I186_R0.7750.95
447_D497_K0.7740.95
276_G280_D0.7640.94
87_Q255_K0.7630.94
126_R129_D0.7620.94
525_M530_I0.7610.94
474_Y478_S0.7600.94
100_A266_G0.7590.94
457_T505_L0.7590.94
50_A136_R0.7570.94
305_D310_E0.7570.94
315_A319_A0.7570.94
180_I202_I0.7540.94
306_A310_E0.7540.94
50_A58_K0.7530.94
350_E353_P0.7520.94
130_V205_T0.7500.94
365_D472_H0.7490.94
110_G113_S0.7490.94
212_V216_D0.7480.94
395_S461_L0.7450.93
396_V438_I0.7430.93
432_T435_A0.7430.93
182_D206_G0.7410.93
88_E110_G0.7410.93
399_V406_I0.7390.93
397_E478_S0.7390.93
87_Q90_I0.7380.93
163_L179_F0.7380.93
331_V386_L0.7370.93
85_L108_I0.7340.93
121_E124_K0.7310.93
66_G70_E0.7300.93
179_F201_A0.7300.93
101_D141_I0.7290.93
381_S424_I0.7280.93
433_P462_A0.7270.93
71_A74_E0.7260.93
536_I540_T0.7260.93
397_E401_A0.7260.93
501_M523_F0.7240.92
163_L168_T0.7240.92
428_V449_F0.7230.92
53_Q57_I0.7220.92
129_D138_L0.7210.92
404_K407_E0.7210.92
430_V436_A0.7210.92
436_A439_A0.7200.92
51_S55_E0.7190.92
390_F393_I0.7190.92
488_V491_A0.7190.92
491_A497_K0.7170.92
288_G534_K0.7160.92
50_A54_L0.7140.92
459_Y462_A0.7110.92
407_E445_E0.7100.92
446_V497_K0.7090.92
132_D136_R0.7090.92
394_I463_V0.7090.92
403_R446_V0.7090.92
45_S48_A0.7090.92
479_P482_L0.7070.92
321_A331_V0.7070.92
261_A537_I0.7060.92
446_V449_F0.7030.91
284_A324_C0.7000.91
218_L229_V0.6990.91
301_F313_Q0.6990.91
378_L424_I0.6980.91
126_R136_R0.6970.91
533_I536_I0.6960.91
476_P505_L0.6950.91
235_V238_K0.6940.91
233_N237_D0.6930.91
104_A138_L0.6930.91
278_V281_V0.6920.91
334_M369_I0.6920.91
382_A421_D0.6920.91
451_I499_T0.6920.91
17_L156_V0.6900.91
50_A57_I0.6890.91
321_A329_V0.6890.91
67_E72_I0.6870.90
168_T201_A0.6840.90
122_Y125_E0.6830.90
490_D518_M0.6810.90
51_S77_I0.6810.90
413_L417_G0.6810.90
266_G541_N0.6790.90
498_W521_D0.6780.90
348_P469_M0.6780.90
328_A425_E0.6770.90
70_E73_F0.6770.90
393_I428_V0.6770.90
414_R419_A0.6760.90
359_A393_I0.6750.90
84_E87_Q0.6740.90
395_S478_S0.6710.89
139_R142_L0.6710.89
271_V525_M0.6710.89
7_A190_T0.6680.89
507_G533_I0.6670.89
302_M307_L0.6650.89
92_L98_M0.6650.89
37_D41_E0.6640.89
378_L388_I0.6630.89
54_L62_G0.6630.89
181_T201_A0.6630.89
141_I231_P0.6620.89
57_I61_A0.6600.89
284_A288_G0.6570.88
420_F424_I0.6570.88
443_A491_A0.6550.88
394_I399_V0.6550.88
512_T536_I0.6530.88
47_R137_L0.6520.88
457_T476_P0.6520.88
54_L57_I0.6510.88
171_L176_V0.6500.88
128_A228_Y0.6490.88
85_L89_I0.6490.88
346_N349_K0.6470.88
147_I151_A0.6470.88
168_T190_T0.6450.87
443_A495_E0.6420.87
58_K62_G0.6420.87
92_L107_V0.6410.87
117_E121_E0.6410.87
159_V212_V0.6390.87
263_T516_L0.6390.87
118_L126_R0.6390.87
38_Q42_R0.6390.87
116_E121_E0.6380.87
93_I262_I0.6360.87
394_I461_L0.6330.86
256_L260_P0.6320.86
171_L179_F0.6310.86
323_A326_S0.6280.86
317_Y373_Q0.6270.86
382_A420_F0.6270.86
3_S226_Q0.6260.86
399_V403_R0.6260.86
260_P263_T0.6220.85
449_F497_K0.6220.85
36_V97_H0.6210.85
402_L405_E0.6200.85
125_E185_G0.6180.85
108_I130_V0.6180.85
73_F76_H0.6180.85
501_M506_A0.6170.85
163_L181_T0.6170.85
481_V485_I0.6170.85
195_R507_G0.6170.85
18_L58_K0.6170.85
121_E229_V0.6160.85
489_I518_M0.6160.85
88_E91_A0.6160.85
102_A105_H0.6150.85
420_F423_S0.6150.85
61_A73_F0.6150.85
264_L534_K0.6140.85
317_Y377_I0.6140.85
159_V227_V0.6120.85
514_L517_G0.6110.84
219_I231_P0.6110.84
287_N531_P0.6110.84
419_A422_E0.6110.84
162_D183_A0.6090.84
399_V445_E0.6080.84
6_L222_A0.6070.84
67_E70_E0.6060.84
366_R369_I0.6050.84
17_L214_N0.6050.84
362_I366_R0.6050.84
395_S463_V0.6040.84
313_Q317_Y0.6030.84
93_I103_A0.6030.84
220_L227_V0.6020.84
399_V402_L0.6020.84
49_K53_Q0.6010.84
107_V110_G0.6010.84
484_L488_V0.6010.84
395_S438_I0.6010.84
367_R371_R0.6000.83
261_A271_V0.6000.83
262_I538_R0.5990.83
471_S479_P0.5990.83
275_I284_A0.5980.83
129_D136_R0.5970.83
479_P483_N0.5970.83
470_I479_P0.5960.83
205_T227_V0.5960.83
176_V199_L0.5960.83
269_V523_F0.5950.83
129_D133_I0.5940.83
412_E416_E0.5930.83
168_T179_F0.5930.83
123_L126_R0.5930.83
385_K421_D0.5910.82
322_E383_F0.5910.82
133_I137_L0.5910.82
531_P534_K0.5900.82
516_L542_F0.5890.82
534_K538_R0.5880.82
272_C330_I0.5880.82
118_L122_Y0.5880.82
181_T203_V0.5870.82
438_I480_S0.5860.82
116_E127_A0.5830.82
508_D512_T0.5830.82
168_T181_T0.5810.81
149_L154_D0.5800.81
341_E349_K0.5800.81
427_G448_F0.5800.81
501_M511_A0.5790.81
278_V319_A0.5780.81
67_E71_A0.5780.81
31_I35_Q0.5780.81
395_S473_L0.5780.81
504_E526_S0.5770.81
353_P458_Q0.5760.81
276_G295_Y0.5750.81
432_T461_L0.5750.81
451_I489_I0.5740.81
417_G420_F0.5740.81
86_E89_I0.5730.81
311_E314_F0.5730.81
149_L152_I0.5720.80
263_T537_I0.5720.80
374_L402_L0.5690.80
118_L121_E0.5690.80
65_F69_K0.5680.80
438_I478_S0.5680.80
137_L142_L0.5660.80
406_I424_I0.5660.80
57_I72_I0.5660.80
44_L52_A0.5660.80
120_D124_K0.5640.79
202_I225_N0.5640.79
457_T475_Q0.5630.79
382_A422_E0.5630.79
22_D42_R0.5630.79
62_G74_E0.5630.79
270_E425_E0.5630.79
307_L372_D0.5630.79
62_G67_E0.5630.79
46_G50_A0.5630.79
333_T402_L0.5620.79
283_G287_N0.5610.79
317_Y388_I0.5610.79
479_P517_G0.5600.79
256_L259_L0.5590.79
475_Q479_P0.5590.79
127_A130_V0.5590.79
525_M529_S0.5580.79
253_L256_L0.5570.79
38_Q46_G0.5570.79
79_L130_V0.5560.79
477_M510_R0.5560.79
179_F190_T0.5530.78
120_D126_R0.5530.78
330_I448_F0.5530.78
319_A322_E0.5530.78
368_E372_D0.5530.78
268_Q541_N0.5530.78
346_N362_I0.5520.78
89_I137_L0.5520.78
42_R46_G0.5510.78
195_R504_E0.5510.78
257_K286_R0.5500.78
20_K214_N0.5500.78
197_L277_T0.5500.78
396_V444_K0.5500.78
7_A203_V0.5500.78
500_G521_D0.5490.78
158_L179_F0.5480.78
321_A382_A0.5480.78
36_V40_V0.5470.77
310_E314_F0.5470.77
334_M362_I0.5450.77
57_I60_K0.5450.77
76_H80_L0.5450.77
133_I138_L0.5440.77
388_I424_I0.5420.77
259_L262_I0.5410.77
281_V329_V0.5410.77
15_K217_Y0.5400.77
488_V497_K0.5390.76
123_L127_A0.5360.76
325_G329_V0.5360.76
167_E181_T0.5350.76
270_E498_W0.5340.76
157_I177_L0.5340.76
163_L190_T0.5340.76
63_E67_E0.5330.76
430_V492_S0.5330.76
407_E424_I0.5330.76
89_I107_V0.5330.76
439_A511_A0.5330.76
16_A216_D0.5320.75
352_N458_Q0.5310.75
336_I344_Y0.5310.75
328_A385_K0.5310.75
145_K148_D0.5310.75
387_R498_W0.5310.75
159_V209_T0.5310.75
64_T70_E0.5310.75
58_K61_A0.5300.75
449_F488_V0.5290.75
64_T67_E0.5290.75
37_D40_V0.5260.75
506_A523_F0.5260.75
280_D284_A0.5250.75
228_Y235_V0.5240.74
466_G501_M0.5240.74
333_T370_L0.5230.74
126_R138_L0.5220.74
321_A385_K0.5220.74
195_R292_V0.5220.74
441_H445_E0.5210.74
28_R102_A0.5200.74
351_E468_D0.5200.74
273_A281_V0.5200.74
191_S201_A0.5200.74
119_D126_R0.5190.74
363_A402_L0.5180.74
359_A457_T0.5180.74
367_R405_E0.5170.73
482_L511_A0.5170.73
20_K23_E0.5160.73
486_K489_I0.5160.73
525_M537_I0.5160.73
511_A515_L0.5160.73
509_E533_I0.5160.73
436_A488_V0.5140.73
496_G499_T0.5130.73
516_L523_F0.5120.73
28_R98_M0.5120.73
425_E447_D0.5110.73
395_S399_V0.5110.73
502_C524_S0.5110.73
65_F70_E0.5110.73
361_R427_G0.5100.72
461_L480_S0.5100.72
146_I153_Q0.5100.72
402_L406_I0.5090.72
257_K261_A0.5090.72
505_L515_L0.5090.72
116_E124_K0.5070.72
396_V399_V0.5060.72
521_D542_F0.5060.72
94_K97_H0.5050.72
150_S155_E0.5050.72
382_A414_R0.5050.72
381_S414_R0.5040.72
23_E26_I0.5030.71
58_K70_E0.5030.71
459_Y463_V0.5030.71
234_E237_D0.5020.71
201_A222_A0.5020.71
256_L531_P0.5010.71
307_L342_L0.5010.71
443_A492_S0.5010.71
18_L214_N0.5000.71
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2hwgA 2 0.9948 100 0.179 Contact Map
2wqdA 2 0.9878 100 0.19 Contact Map
1kblA 2 0.8957 100 0.337 Contact Map
1vbgA 2 0.8922 100 0.344 Contact Map
2x0sA 2 0.9252 100 0.352 Contact Map
2olsA 2 0.7443 100 0.43 Contact Map
2xz9A 2 0.5513 100 0.547 Contact Map
1zymA 2 0.4313 100 0.679 Contact Map
4l9zA 5 0.4835 100 0.783 Contact Map
3qqwA 3 0.4887 100 0.784 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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