DSDX - ECOLI - GREMLIN Contacts

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DSDX - DsdX permease

UniProt:	P08555	Sequences: MHSQIWVVSTLLISIVLIVLTIVKFKFHPFLALLLASFFVGTMMGMGPLDMVNAIESGIGGTLGFLAAVIGLGTILGKMMEVSGAAERIGLTLQRCRWLSVDVIMVLVGLICGITLFVEVGVVLLIPLAFSIAKKTNTSLLKLAIPLCTALMAVHCVVPPHPAALYVANKLGADIGSVIVYGLLVGLMASLIGGPLFLKFLGQRLPFKPVPTEFADLKVRDEKTLPSLGATLFTILLPIALMLVKTIAELNMARESGLYILVEFIGNPITAMFIAVFVAYYVLGIRQHMSMGTMLTHTENGFGSIANILLIIGAGGAFNAILKSSSLADTLAVILSNMHMHPILLAWLVALILHAAVGSATVAMMGATAIVAPMLPLYPDISPEIIAIAIGSGAIGCTIVTDSLFWLVKQYCGATLNETFKYYTTATFIASVVALAGTFLLSFII	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10250
Length:	445 (418)
Sequences:	5865 (3979)
Seq/√Len:	194.6

ECOLI - DSDX GNTU YJHF GNTP YGBN IDNT GNTT DCUD DCUC YFCC
BACSU - GNTP YOJA YXJC CITM CITN YRAO YCGA
HALSA - Q9HNR2 Q9HNF6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
92_T	95_R	3.627	1.00
300_N	303_G	3.477	1.00
290_S	293_T	3.419	1.00
268_P	272_M	3.404	1.00
234_T	238_P	2.829	1.00
320_A	324_S	2.809	1.00
14_S	318_F	2.807	1.00
329_D	333_V	2.742	1.00
201_L	205_L	2.733	1.00
415_T	418_E	2.715	1.00
268_P	271_A	2.713	1.00
82_V	297_H	2.710	1.00
17_L	39_F	2.672	1.00
200_F	204_R	2.666	1.00
14_S	40_V	2.634	1.00
338_M	341_H	2.586	1.00
228_L	232_L	2.575	1.00
205_L	209_P	2.476	1.00
237_L	278_V	2.451	1.00
202_G	205_L	2.444	1.00
53_N	57_S	2.386	1.00
428_F	432_V	2.372	1.00
238_P	242_M	2.318	1.00
204_R	208_K	2.287	1.00
231_T	234_T	2.284	1.00
192_I	433_V	2.260	1.00
82_V	293_T	2.253	1.00
54_A	324_S	2.253	1.00
347_W	431_S	2.247	1.00
201_L	204_R	2.246	1.00
333_V	336_S	2.225	1.00
114_I	117_F	2.190	1.00
16_V	20_L	2.190	1.00
20_L	24_K	2.187	1.00
92_T	228_L	2.185	1.00
229_G	233_F	2.179	1.00
436_A	440_L	2.141	1.00
344_L	435_L	2.125	1.00
50_D	53_N	2.106	1.00
184_L	188_M	2.083	1.00
47_G	50_D	2.080	1.00
203_Q	207_F	2.080	1.00
205_L	208_K	2.079	1.00
208_K	211_P	2.067	1.00
204_R	207_F	2.014	1.00
350_A	367_A	1.995	1.00
234_T	242_M	1.995	1.00
197_F	201_L	1.951	1.00
380_D	383_P	1.948	1.00
87_E	91_L	1.945	1.00
187_L	191_L	1.909	1.00
201_L	208_K	1.907	1.00
227_S	230_A	1.891	1.00
235_I	242_M	1.882	1.00
272_M	276_V	1.861	1.00
198_L	201_L	1.848	1.00
109_G	112_C	1.845	1.00
432_V	436_A	1.818	1.00
375_L	386_I	1.809	1.00
57_S	61_G	1.775	1.00
242_M	246_T	1.717	1.00
171_L	390_I	1.710	1.00
330_T	334_I	1.708	1.00
204_R	209_P	1.703	1.00
199_K	203_Q	1.656	1.00
202_G	206_P	1.647	1.00
271_A	276_V	1.643	1.00
421_K	425_T	1.640	1.00
238_P	246_T	1.626	1.00
203_Q	206_P	1.622	1.00
47_G	51_M	1.621	1.00
201_L	209_P	1.612	1.00
246_T	250_L	1.600	1.00
206_P	209_P	1.591	1.00
10_T	43_M	1.578	1.00
103_V	195_P	1.575	1.00
351_L	396_G	1.564	1.00
196_L	200_F	1.549	1.00
206_P	210_V	1.545	1.00
174_D	177_S	1.542	1.00
78_K	82_V	1.532	1.00
186_G	189_A	1.530	1.00
144_A	412_C	1.523	1.00
97_R	100_S	1.513	1.00
229_G	234_T	1.508	1.00
346_A	390_I	1.504	1.00
268_P	273_F	1.500	1.00
200_F	203_Q	1.493	1.00
178_V	387_A	1.492	1.00
439_F	442_S	1.486	1.00
241_L	245_K	1.484	1.00
293_T	296_T	1.480	1.00
120_V	123_V	1.477	1.00
277_F	281_Y	1.468	1.00
355_A	397_C	1.466	1.00
235_I	238_P	1.464	1.00
167_V	364_M	1.457	1.00
197_F	200_F	1.453	1.00
228_L	231_T	1.443	1.00
54_A	320_A	1.436	1.00
202_G	209_P	1.428	1.00
74_T	298_T	1.424	1.00
296_T	300_N	1.424	1.00
17_L	36_A	1.401	1.00
246_T	249_E	1.399	1.00
59_I	67_A	1.392	1.00
18_I	36_A	1.391	1.00
199_K	202_G	1.379	1.00
231_T	238_P	1.373	1.00
108_V	112_C	1.373	1.00
105_M	108_V	1.371	1.00
203_Q	209_P	1.363	1.00
425_T	429_I	1.362	1.00
203_Q	208_K	1.358	1.00
241_L	274_I	1.355	1.00
88_R	92_T	1.349	1.00
108_V	111_I	1.344	1.00
198_L	202_G	1.335	1.00
196_L	199_K	1.332	1.00
194_G	198_L	1.330	1.00
194_G	197_F	1.330	1.00
27_F	32_A	1.328	1.00
243_L	246_T	1.319	1.00
114_I	118_V	1.311	1.00
376_P	383_P	1.308	1.00
230_A	234_T	1.307	1.00
202_G	208_K	1.285	1.00
239_I	242_M	1.281	1.00
156_C	395_I	1.281	1.00
245_K	249_E	1.276	1.00
248_A	252_M	1.274	1.00
204_R	211_P	1.270	1.00
107_L	111_I	1.267	1.00
55_I	317_A	1.266	1.00
234_T	250_L	1.260	1.00
226_P	231_T	1.258	1.00
263_E	266_G	1.257	1.00
275_A	279_A	1.248	1.00
409_K	419_T	1.244	1.00
78_K	297_H	1.242	1.00
186_G	190_S	1.239	1.00
118_V	121_G	1.223	1.00
416_L	420_F	1.215	1.00
319_N	323_K	1.215	1.00
230_A	233_F	1.214	1.00
185_V	441_L	1.213	1.00
117_F	120_V	1.213	1.00
409_K	416_L	1.208	1.00
205_L	210_V	1.204	1.00
197_F	204_R	1.203	1.00
39_F	43_M	1.203	1.00
231_T	250_L	1.202	1.00
53_N	56_E	1.200	1.00
198_L	205_L	1.197	1.00
82_V	300_N	1.187	1.00
134_K	140_L	1.186	1.00
270_T	274_I	1.185	1.00
183_L	187_L	1.175	1.00
17_L	21_T	1.173	1.00
271_A	279_A	1.169	1.00
62_T	316_G	1.162	1.00
181_Y	185_V	1.159	1.00
200_F	208_K	1.158	1.00
204_R	210_V	1.155	1.00
106_V	190_S	1.155	1.00
137_N	208_K	1.153	1.00
98_W	135_K	1.152	1.00
180_V	183_L	1.149	1.00
245_K	250_L	1.146	1.00
240_A	244_V	1.146	1.00
426_A	430_A	1.144	1.00
197_F	205_L	1.142	1.00
180_V	184_L	1.128	1.00
119_E	403_S	1.122	1.00
266_G	271_A	1.113	1.00
280_Y	283_L	1.105	1.00
392_S	438_T	1.093	1.00
207_F	211_P	1.091	1.00
182_G	185_V	1.091	1.00
270_T	276_V	1.090	1.00
278_V	282_V	1.090	1.00
181_Y	388_I	1.087	1.00
195_P	202_G	1.081	1.00
229_G	232_L	1.079	1.00
249_E	252_M	1.077	1.00
185_V	188_M	1.077	1.00
389_A	393_G	1.076	1.00
105_M	111_I	1.076	1.00
97_R	101_V	1.073	1.00
181_Y	184_L	1.067	1.00
269_I	273_F	1.065	1.00
359_S	362_V	1.056	1.00
233_F	237_L	1.051	1.00
396_G	431_S	1.051	1.00
196_L	204_R	1.050	1.00
213_E	216_D	1.047	1.00
378_Y	381_I	1.038	1.00
168_A	172_G	1.035	1.00
192_I	196_L	1.031	1.00
86_A	90_G	1.031	1.00
195_P	198_L	1.029	1.00
197_F	202_G	1.027	1.00
87_E	223_K	1.026	1.00
69_V	312_I	1.025	1.00
85_A	231_T	1.023	1.00
272_M	275_A	1.020	1.00
347_W	435_L	1.017	1.00
32_A	36_A	1.014	1.00
269_I	272_M	1.011	1.00
280_Y	284_G	1.009	1.00
246_T	251_N	1.005	1.00
105_M	109_G	1.003	1.00
14_S	39_F	1.003	1.00
119_E	312_I	1.001	1.00
58_G	320_A	1.001	1.00
382_S	385_I	1.001	1.00
244_V	248_A	0.997	1.00
222_E	225_L	0.994	1.00
271_A	282_V	0.992	1.00
326_S	329_D	0.987	0.99
36_A	39_F	0.987	0.99
437_G	441_L	0.984	0.99
228_L	234_T	0.982	0.99
417_N	421_K	0.981	0.99
91_L	135_K	0.980	0.99
192_I	429_I	0.980	0.99
201_L	211_P	0.978	0.99
214_F	218_K	0.973	0.99
247_I	251_N	0.972	0.99
197_F	429_I	0.971	0.99
201_L	206_P	0.968	0.99
214_F	217_L	0.966	0.99
203_Q	211_P	0.966	0.99
289_M	294_M	0.966	0.99
398_T	402_D	0.965	0.99
231_T	235_I	0.956	0.99
292_G	296_T	0.956	0.99
49_L	53_N	0.945	0.99
149_T	194_G	0.942	0.99
226_P	230_A	0.937	0.99
76_L	275_A	0.937	0.99
196_L	203_Q	0.937	0.99
97_R	104_I	0.936	0.99
396_G	428_F	0.935	0.99
170_K	368_T	0.934	0.99
392_S	434_A	0.934	0.99
185_V	437_G	0.933	0.99
276_V	280_Y	0.933	0.99
272_M	280_Y	0.930	0.99
191_L	196_L	0.928	0.99
118_V	404_L	0.928	0.99
227_S	231_T	0.923	0.99
225_L	229_G	0.920	0.99
170_K	173_A	0.919	0.99
433_V	437_G	0.917	0.99
268_P	276_V	0.913	0.99
40_V	43_M	0.909	0.99
201_L	207_F	0.909	0.99
237_L	240_A	0.905	0.99
83_S	283_L	0.905	0.99
222_E	227_S	0.905	0.99
145_I	149_T	0.903	0.99
244_V	250_L	0.899	0.99
320_A	323_K	0.896	0.99
231_T	242_M	0.895	0.99
238_P	241_L	0.894	0.99
246_T	252_M	0.893	0.99
245_K	248_A	0.891	0.99
228_L	242_M	0.890	0.99
424_T	428_F	0.886	0.99
239_I	243_L	0.884	0.99
107_L	110_L	0.882	0.99
312_I	403_S	0.879	0.99
220_R	224_T	0.878	0.99
268_P	279_A	0.876	0.99
355_A	396_G	0.875	0.99
279_A	283_L	0.875	0.99
266_G	279_A	0.875	0.99
154_V	161_H	0.866	0.99
200_F	206_P	0.865	0.99
264_F	267_N	0.863	0.99
122_V	411_Y	0.863	0.99
271_A	275_A	0.862	0.99
279_A	282_V	0.862	0.99
169_N	172_G	0.860	0.99
434_A	438_T	0.860	0.99
372_A	376_P	0.856	0.99
106_V	110_L	0.853	0.99
247_I	250_L	0.852	0.99
119_E	123_V	0.847	0.98
418_E	421_K	0.846	0.98
427_T	430_A	0.846	0.98
263_E	267_N	0.845	0.98
188_M	192_I	0.845	0.98
106_V	112_C	0.844	0.98
105_M	110_L	0.842	0.98
205_L	211_P	0.839	0.98
220_R	223_K	0.838	0.98
199_K	207_F	0.838	0.98
243_L	247_I	0.837	0.98
229_G	238_P	0.836	0.98
79_M	279_A	0.836	0.98
238_P	243_L	0.834	0.98
289_M	293_T	0.833	0.98
37_S	41_G	0.830	0.98
227_S	233_F	0.829	0.98
113_G	117_F	0.828	0.98
242_M	250_L	0.827	0.98
228_L	236_L	0.826	0.98
199_K	205_L	0.825	0.98
233_F	282_V	0.824	0.98
99_L	103_V	0.823	0.98
106_V	109_G	0.823	0.98
57_S	324_S	0.823	0.98
224_T	228_L	0.820	0.98
224_T	227_S	0.820	0.98
364_M	394_A	0.818	0.98
104_I	110_L	0.818	0.98
188_M	191_L	0.816	0.98
229_G	251_N	0.815	0.98
242_M	245_K	0.814	0.98
272_M	279_A	0.814	0.98
198_L	204_R	0.813	0.98
268_P	275_A	0.812	0.98
222_E	226_P	0.812	0.98
40_V	318_F	0.809	0.98
244_V	249_E	0.809	0.98
228_L	235_I	0.808	0.98
344_L	439_F	0.808	0.98
388_I	438_T	0.805	0.98
225_L	228_L	0.803	0.98
54_A	57_S	0.797	0.98
398_T	423_Y	0.790	0.98
397_C	424_T	0.789	0.98
305_I	309_L	0.787	0.98
91_L	94_Q	0.787	0.98
145_I	422_Y	0.786	0.97
354_H	402_D	0.785	0.97
234_T	282_V	0.784	0.97
178_V	384_E	0.784	0.97
360_A	398_T	0.784	0.97
30_F	310_L	0.784	0.97
351_L	431_S	0.779	0.97
435_L	439_F	0.779	0.97
200_F	205_L	0.778	0.97
290_S	294_M	0.775	0.97
354_H	360_A	0.772	0.97
40_V	321_I	0.771	0.97
202_G	207_F	0.768	0.97
293_T	297_H	0.762	0.97
105_M	112_C	0.761	0.97
76_L	276_V	0.760	0.97
277_F	282_V	0.759	0.97
57_S	60_G	0.759	0.97
237_L	241_L	0.758	0.97
89_I	231_T	0.757	0.97
52_V	56_E	0.756	0.97
404_L	408_V	0.755	0.97
35_L	39_F	0.753	0.97
73_G	301_G	0.750	0.97
226_P	238_P	0.748	0.97
194_G	201_L	0.746	0.97
194_G	200_F	0.745	0.97
181_Y	384_E	0.744	0.96
133_A	143_L	0.744	0.96
104_I	111_I	0.743	0.96
338_M	342_P	0.743	0.96
357_V	366_G	0.741	0.96
119_E	122_V	0.741	0.96
268_P	274_I	0.739	0.96
11_L	15_I	0.739	0.96
269_I	279_A	0.739	0.96
232_L	235_I	0.738	0.96
207_F	210_V	0.738	0.96
299_E	303_G	0.737	0.96
21_T	32_A	0.737	0.96
152_M	427_T	0.735	0.96
168_A	171_L	0.735	0.96
120_V	163_A	0.733	0.96
373_P	378_Y	0.731	0.96
220_R	227_S	0.731	0.96
78_K	81_E	0.731	0.96
54_A	58_G	0.729	0.96
31_L	276_V	0.729	0.96
85_A	88_R	0.728	0.96
277_F	283_L	0.728	0.96
21_T	27_F	0.726	0.96
276_V	282_V	0.722	0.96
30_F	34_L	0.722	0.96
10_T	13_I	0.719	0.96
103_V	107_L	0.719	0.96
269_I	276_V	0.718	0.96
115_T	118_V	0.717	0.96
234_T	237_L	0.715	0.96
46_M	50_D	0.715	0.96
102_D	105_M	0.714	0.96
354_H	363_A	0.714	0.96
237_L	275_A	0.714	0.96
236_L	242_M	0.713	0.96
17_L	20_L	0.712	0.96
363_A	402_D	0.707	0.95
138_T	142_K	0.707	0.95
177_S	180_V	0.706	0.95
189_A	437_G	0.705	0.95
267_N	271_A	0.701	0.95
184_L	191_L	0.701	0.95
113_G	118_V	0.699	0.95
148_C	405_F	0.698	0.95
38_F	270_T	0.696	0.95
202_G	210_V	0.695	0.95
150_A	154_V	0.694	0.95
248_A	251_N	0.693	0.95
44_M	47_G	0.693	0.95
226_P	242_M	0.691	0.95
88_R	228_L	0.690	0.95
28_H	31_L	0.690	0.95
154_V	158_V	0.688	0.95
346_A	371_V	0.688	0.95
335_L	349_V	0.686	0.95
225_L	232_L	0.686	0.95
12_L	16_V	0.684	0.94
68_A	72_L	0.684	0.94
311_I	365_M	0.683	0.94
215_A	218_K	0.683	0.94
230_A	238_P	0.681	0.94
350_A	363_A	0.680	0.94
423_Y	427_T	0.679	0.94
357_V	362_V	0.677	0.94
188_M	437_G	0.677	0.94
197_F	425_T	0.675	0.94
97_R	102_D	0.674	0.94
116_L	119_E	0.674	0.94
380_D	384_E	0.673	0.94
78_K	300_N	0.672	0.94
133_A	138_T	0.670	0.94
235_I	246_T	0.668	0.94
177_S	384_E	0.664	0.94
233_F	250_L	0.663	0.93
360_A	394_A	0.663	0.93
46_M	54_A	0.662	0.93
249_E	263_E	0.662	0.93
166_Y	365_M	0.660	0.93
280_Y	298_T	0.658	0.93
218_K	221_D	0.656	0.93
214_F	220_R	0.656	0.93
226_P	234_T	0.656	0.93
228_L	238_P	0.655	0.93
110_L	114_I	0.655	0.93
213_E	217_L	0.653	0.93
98_W	101_V	0.652	0.93
121_G	151_L	0.651	0.93
232_L	238_P	0.650	0.93
97_R	112_C	0.645	0.93
270_T	273_F	0.644	0.92
267_N	276_V	0.644	0.92
179_I	182_G	0.644	0.92
373_P	377_L	0.643	0.92
112_C	125_L	0.643	0.92
354_H	398_T	0.642	0.92
182_G	186_G	0.638	0.92
343_I	381_I	0.638	0.92
281_Y	284_G	0.638	0.92
103_V	110_L	0.637	0.92
245_K	251_N	0.636	0.92
291_M	294_M	0.634	0.92
185_V	388_I	0.634	0.92
330_T	333_V	0.634	0.92
179_I	183_L	0.632	0.92
100_S	104_I	0.631	0.92
271_A	283_L	0.631	0.92
387_A	430_A	0.631	0.92
363_A	367_A	0.629	0.92
299_E	302_F	0.628	0.92
13_I	17_L	0.627	0.91
234_T	241_L	0.626	0.91
271_A	274_I	0.626	0.91
194_G	204_R	0.625	0.91
114_I	154_V	0.625	0.91
288_H	294_M	0.622	0.91
114_I	119_E	0.621	0.91
10_T	14_S	0.620	0.91
224_T	229_G	0.619	0.91
198_L	209_P	0.619	0.91
354_H	394_A	0.619	0.91
360_A	403_S	0.616	0.91
153_A	430_A	0.614	0.91
245_K	252_M	0.614	0.91
44_M	325_S	0.614	0.91
345_L	375_L	0.612	0.90
399_I	427_T	0.612	0.90
217_L	220_R	0.612	0.90
9_S	13_I	0.611	0.90
424_T	431_S	0.610	0.90
374_M	378_Y	0.608	0.90
231_T	246_T	0.607	0.90
351_L	397_C	0.606	0.90
350_A	394_A	0.603	0.90
422_Y	425_T	0.603	0.90
129_A	133_A	0.603	0.90
419_T	423_Y	0.602	0.90
195_P	199_K	0.601	0.90
388_I	392_S	0.601	0.90
41_G	51_M	0.601	0.90
272_M	283_L	0.600	0.90
341_H	344_L	0.600	0.90
232_L	236_L	0.600	0.90
195_P	204_R	0.598	0.89
113_G	119_E	0.597	0.89
231_T	249_E	0.592	0.89
10_T	36_A	0.589	0.89
170_K	369_A	0.588	0.89
200_F	211_P	0.587	0.89
68_A	71_G	0.586	0.88
199_K	204_R	0.585	0.88
269_I	277_F	0.584	0.88
195_P	200_F	0.584	0.88
115_T	119_E	0.582	0.88
268_P	283_L	0.581	0.88
99_L	104_I	0.581	0.88
238_P	250_L	0.578	0.88
113_G	120_V	0.578	0.88
173_A	178_V	0.577	0.88
142_K	202_G	0.575	0.88
129_A	147_L	0.573	0.87
194_G	199_K	0.571	0.87
200_F	207_F	0.569	0.87
181_Y	188_M	0.569	0.87
10_T	39_F	0.568	0.87
187_L	190_S	0.568	0.87
340_M	344_L	0.568	0.87
353_L	357_V	0.567	0.87
155_H	159_P	0.567	0.87
113_G	154_V	0.565	0.87
362_V	366_G	0.565	0.87
233_F	236_L	0.565	0.87
283_L	294_M	0.565	0.87
88_R	227_S	0.564	0.87
21_T	35_L	0.562	0.86
284_G	288_H	0.562	0.86
152_M	395_I	0.562	0.86
385_I	438_T	0.562	0.86
14_S	18_I	0.562	0.86
332_A	366_G	0.561	0.86
225_L	231_T	0.560	0.86
333_V	337_N	0.560	0.86
104_I	107_L	0.559	0.86
400_V	420_F	0.559	0.86
273_F	276_V	0.558	0.86
10_T	44_M	0.558	0.86
265_I	269_I	0.555	0.86
433_V	436_A	0.554	0.86
236_L	243_L	0.553	0.85
178_V	181_Y	0.553	0.85
91_L	225_L	0.552	0.85
438_T	442_S	0.550	0.85
103_V	111_I	0.546	0.85
238_P	251_N	0.545	0.85
158_V	161_H	0.542	0.84
17_L	24_K	0.541	0.84
228_L	233_F	0.541	0.84
131_S	331_L	0.540	0.84
238_P	249_E	0.539	0.84
270_T	283_L	0.539	0.84
226_P	240_A	0.539	0.84
347_W	351_L	0.538	0.84
197_F	208_K	0.537	0.84
60_G	64_G	0.537	0.84
11_L	14_S	0.537	0.84
221_D	224_T	0.536	0.84
225_L	238_P	0.535	0.84
113_G	116_L	0.535	0.84
142_K	146_P	0.535	0.84
277_F	284_G	0.535	0.84
118_V	122_V	0.534	0.83
198_L	206_P	0.533	0.83
342_P	378_Y	0.532	0.83
417_N	420_F	0.531	0.83
88_R	231_T	0.531	0.83
199_K	209_P	0.529	0.83
15_I	18_I	0.528	0.83
216_D	221_D	0.528	0.83
148_C	406_W	0.527	0.83
117_F	163_A	0.527	0.83
11_L	327_L	0.527	0.83
57_S	320_A	0.526	0.83
182_G	190_S	0.525	0.82
134_K	137_N	0.525	0.82
217_L	221_D	0.525	0.82
244_V	251_N	0.524	0.82
437_G	440_L	0.523	0.82
114_I	120_V	0.523	0.82
157_V	392_S	0.522	0.82
198_L	208_K	0.521	0.82
175_I	184_L	0.521	0.82
269_I	283_L	0.520	0.82
267_N	272_M	0.520	0.82
153_A	186_G	0.519	0.82
264_F	268_P	0.519	0.82
175_I	179_I	0.518	0.82
234_T	246_T	0.518	0.82
267_N	270_T	0.516	0.81
314_A	318_F	0.516	0.81
346_A	350_A	0.516	0.81
242_M	249_E	0.515	0.81
57_S	329_D	0.513	0.81
51_M	56_E	0.512	0.81
398_T	401_T	0.512	0.81
397_C	428_F	0.512	0.81
422_Y	426_A	0.512	0.81
121_G	161_H	0.511	0.81
106_V	146_P	0.509	0.80
78_K	304_S	0.508	0.80
242_M	248_A	0.508	0.80
178_V	182_G	0.508	0.80
184_L	189_A	0.506	0.80
182_G	188_M	0.506	0.80
346_A	386_I	0.506	0.80
231_T	251_N	0.504	0.80
397_C	420_F	0.504	0.80
284_G	294_M	0.504	0.80
13_I	16_V	0.503	0.80
198_L	203_Q	0.502	0.80
221_D	337_N	0.501	0.79
280_Y	294_M	0.501	0.79
139_S	205_L	0.501	0.79
36_A	128_L	0.500	0.79
328_A	332_A	0.500	0.79

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4r1iA	2	0.973	100	0.571	Contact Map
4r0cA	3	0.964	100	0.585	Contact Map
4f35D	2	0.8921	100	0.634	Contact Map
4pd6A	3	0.7573	63.3	0.949	Contact Map
4dx5A	3	0.3843	52.2	0.952	Contact Map
2nwlA	3	0.7326	52	0.952	Contact Map
3aqpA	1	0.3371	48	0.954	Contact Map
2cfqA	1	0.8157	46.5	0.954	Contact Map
3qe7A	2	0.4494	40.6	0.956	Contact Map
4k0jA	3	0.3236	37.8	0.956	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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