CREC - ECOLI - GREMLIN Contacts

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CREC - Sensor protein CreC

UniProt:	P08401	Sequences: MRIGMRLLLGYFLLVAVAAWFVLAIFVKEVKPGVRRATEGTLIDTATLLAELARPDLLSGDPTHGQLAQAFNQLQHRPFRANIGGINKVRNEYHVYMTDAQGKVLFDSANKAVGQDYSRWNDVWLTLRGQYGARSTLQNPADPESSVMYVAAPIMDGSRLIGVLSVGKPNAAMAPVIKRSERRILWASAILLGIALVIGAGMVWWINRSIARLTRYADSVTDNKPVPLPDLGSSELRKLAQALESMRVKLEGKNYIEQYVYALTHELKSPLAAIRGAAEILREGPPPEVVARFTDNILTQNARMQALVETLLRQARLENRQEVVLTAVDVAALFRRVSEARTVQLAEKKITLHVTPTEVNVAAEPALLEQALGNLLDNAIDFTPESGCITLSAEVDQEHVTLKVLDTGSGIPDYALSRIFERFYSLPRANGQKSSGLGLAFVSEVARLFNGEVTLRNVQEGGVLASLRLHRHFT	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10730
Length:	474 (438)
Sequences:	50388 (43896)
Seq/√Len:	2097.4

ECOLI - CREC BARA TORS GLRK CUSS PHOQ QSEC BAES YEDV CPXA ATOS ENVZ RCSC RCSD RSTB ZRAS DPIB DCUS ARCB EVGS NARX NARQ KDPD BASS PHOR YPDA NTRB UHPB
BACSU - YCLK YKOH YYCG YVRG CSSS RESE PHOR KIND DCTS CITS MALK YESM KINE YVCQ YRKQ KINB YXDK KINA YCBM BCES KINC LYTS COMP GLNK LIAS DEGS YBDK YWPD YHCY NATK
HALSA - Q9HQ15 Q9HQG5 Q9HQ16 Q9HQE9 Q9HRE4 Q9HR10 O51970 Q9HRG1 Q9HNM2 BAT Q9HNA6 Q9HQB9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
406_D	410_G	3.951	1.00
405_L	464_L	3.896	1.00
443_S	447_R	3.645	1.00
278_A	297_I	3.638	1.00
328_V	363_A	3.534	1.00
454_T	466_S	3.472	1.00
399_H	468_R	3.422	1.00
383_T	407_T	2.958	1.00
403_K	464_L	2.933	1.00
392_S	403_K	2.861	1.00
458_V	461_G	2.816	1.00
412_P	415_A	2.763	1.00
401_T	468_R	2.752	1.00
363_A	449_F	2.741	1.00
416_L	457_N	2.731	1.00
401_T	466_S	2.701	1.00
403_K	466_S	2.656	1.00
394_E	401_T	2.638	1.00
390_T	405_L	2.634	1.00
353_H	390_T	2.618	1.00
282_R	298_L	2.612	1.00
455_L	465_A	2.607	1.00
327_A	362_A	2.605	1.00
442_V	453_V	2.596	1.00
282_R	295_D	2.583	1.00
416_L	455_L	2.487	1.00
353_H	388_C	2.452	1.00
275_R	302_A	2.437	1.00
371_A	446_A	2.432	1.00
388_C	407_T	2.415	1.00
446_A	451_G	2.402	1.00
392_S	405_L	2.383	1.00
234_S	237_R	2.372	1.00
355_T	392_S	2.369	1.00
456_R	464_L	2.363	1.00
394_E	403_K	2.347	1.00
457_N	463_V	2.301	1.00
329_D	332_A	2.281	1.00
275_R	301_N	2.276	1.00
420_F	453_V	2.262	1.00
326_T	365_P	2.259	1.00
456_R	466_S	2.235	1.00
336_R	369_E	2.181	1.00
411_I	419_I	2.123	1.00
247_R	250_L	2.112	1.00
327_A	360_N	2.101	1.00
446_A	467_L	2.093	1.00
415_A	418_R	2.086	1.00
287_P	290_V	2.080	1.00
355_T	390_T	2.051	1.00
351_T	388_C	2.051	1.00
452_E	468_R	2.035	1.00
341_R	373_G	2.015	1.00
219_S	224_K	2.004	1.00
411_I	415_A	1.999	1.00
383_T	387_G	1.992	1.00
371_A	445_V	1.986	1.00
99_D	103_K	1.979	1.00
413_D	416_L	1.953	1.00
246_M	250_L	1.873	1.00
371_A	442_V	1.865	1.00
345_L	380_I	1.864	1.00
286_P	290_V	1.860	1.00
236_L	240_A	1.838	1.00
387_G	407_T	1.813	1.00
372_L	402_L	1.811	1.00
279_E	298_L	1.802	1.00
305_Q	309_E	1.790	1.00
447_R	452_E	1.790	1.00
363_A	368_L	1.789	1.00
331_A	393_A	1.769	1.00
445_V	449_F	1.769	1.00
418_R	424_Y	1.756	1.00
396_D	401_T	1.749	1.00
244_E	247_R	1.733	1.00
254_N	258_Q	1.722	1.00
233_S	237_R	1.717	1.00
325_L	362_A	1.714	1.00
418_R	421_E	1.709	1.00
232_G	237_R	1.705	1.00
454_T	468_R	1.691	1.00
402_L	467_L	1.681	1.00
282_R	291_A	1.668	1.00
258_Q	262_A	1.654	1.00
278_A	298_L	1.650	1.00
415_A	424_Y	1.648	1.00
256_I	260_V	1.633	1.00
457_N	461_G	1.622	1.00
275_R	305_Q	1.619	1.00
247_R	251_E	1.619	1.00
277_A	293_F	1.609	1.00
383_T	389_I	1.599	1.00
281_L	294_T	1.589	1.00
377_D	381_D	1.568	1.00
364_E	367_L	1.565	1.00
412_P	459_Q	1.540	1.00
411_I	463_V	1.531	1.00
286_P	289_V	1.522	1.00
390_T	407_T	1.495	1.00
96_Y	165_S	1.492	1.00
382_F	425_S	1.490	1.00
367_L	370_Q	1.481	1.00
371_A	467_L	1.461	1.00
329_D	358_E	1.454	1.00
24_A	28_K	1.453	1.00
406_D	462_G	1.453	1.00
331_A	335_R	1.436	1.00
374_N	442_V	1.430	1.00
342_T	346_A	1.424	1.00
274_I	301_N	1.421	1.00
233_S	236_L	1.413	1.00
240_A	244_E	1.412	1.00
415_A	426_L	1.405	1.00
298_L	302_A	1.394	1.00
421_E	424_Y	1.391	1.00
457_N	460_E	1.391	1.00
446_A	453_V	1.379	1.00
329_D	360_N	1.367	1.00
336_R	365_P	1.357	1.00
281_L	290_V	1.356	1.00
275_R	298_L	1.354	1.00
229_P	232_G	1.338	1.00
236_L	239_L	1.333	1.00
237_R	240_A	1.331	1.00
416_L	420_F	1.327	1.00
214_T	218_D	1.317	1.00
211_A	214_T	1.307	1.00
399_H	452_E	1.304	1.00
323_V	364_E	1.279	1.00
243_L	246_M	1.270	1.00
273_A	300_Q	1.268	1.00
419_I	455_L	1.266	1.00
274_I	297_I	1.259	1.00
278_A	282_R	1.250	1.00
94_H	167_G	1.244	1.00
420_F	455_L	1.240	1.00
344_Q	347_E	1.234	1.00
93_Y	168_K	1.231	1.00
365_P	369_E	1.227	1.00
273_A	277_A	1.220	1.00
98_T	104_V	1.218	1.00
451_G	469_L	1.217	1.00
220_V	247_R	1.214	1.00
199_G	203_V	1.212	1.00
367_L	448_L	1.210	1.00
340_A	369_E	1.208	1.00
284_G	290_V	1.187	1.00
444_E	447_R	1.176	1.00
334_F	393_A	1.172	1.00
277_A	296_N	1.171	1.00
295_D	299_T	1.165	1.00
420_F	465_A	1.163	1.00
338_S	354_V	1.156	1.00
259_Y	263_L	1.153	1.00
252_G	255_Y	1.147	1.00
367_L	445_V	1.136	1.00
233_S	240_A	1.130	1.00
333_L	337_V	1.129	1.00
455_L	463_V	1.126	1.00
177_I	181_E	1.121	1.00
411_I	416_L	1.117	1.00
178_K	182_R	1.116	1.00
217_A	221_T	1.115	1.00
325_L	449_F	1.113	1.00
262_A	422_R	1.112	1.00
80_R	84_G	1.103	1.00
155_M	160_L	1.103	1.00
306_A	366_A	1.103	1.00
278_A	294_T	1.101	1.00
278_A	301_N	1.097	1.00
359_V	395_V	1.096	1.00
214_T	238_K	1.091	1.00
227_P	248_V	1.090	1.00
94_H	107_D	1.087	1.00
359_V	400_V	1.076	1.00
266_E	370_Q	1.075	1.00
240_A	243_L	1.074	1.00
287_P	291_A	1.071	1.00
337_V	376_L	1.069	1.00
368_L	449_F	1.065	1.00
427_P	432_Q	1.058	1.00
406_D	463_V	1.058	1.00
335_R	354_V	1.055	1.00
300_Q	303_R	1.051	1.00
213_L	217_A	1.049	1.00
312_L	315_A	1.046	1.00
411_I	455_L	1.041	1.00
219_S	226_V	1.040	1.00
203_V	207_N	1.036	1.00
285_P	290_V	1.032	1.00
25_I	29_E	1.028	1.00
184_I	188_S	1.026	1.00
292_R	296_N	1.025	1.00
237_R	241_Q	1.019	1.00
276_G	280_I	1.018	1.00
375_L	465_A	1.018	1.00
379_A	389_I	1.002	1.00
217_A	220_V	1.000	1.00
245_S	249_K	0.994	1.00
239_L	243_L	0.990	1.00
323_V	367_L	0.987	1.00
96_Y	104_V	0.983	1.00
266_E	374_N	0.980	1.00
174_A	177_I	0.979	1.00
291_A	295_D	0.976	1.00
341_R	376_L	0.976	1.00
372_L	404_V	0.976	1.00
242_A	245_S	0.973	1.00
372_L	376_L	0.969	1.00
375_L	453_V	0.969	1.00
225_P	251_E	0.968	1.00
332_A	336_R	0.967	1.00
309_E	313_R	0.967	1.00
173_M	177_I	0.964	1.00
422_R	444_E	0.957	1.00
296_N	300_Q	0.957	1.00
396_D	399_H	0.956	1.00
197_V	201_G	0.951	1.00
337_V	369_E	0.948	1.00
170_N	174_A	0.947	1.00
151_A	163_V	0.946	1.00
340_A	373_G	0.945	1.00
374_N	377_D	0.942	1.00
446_A	469_L	0.939	1.00
246_M	249_K	0.938	1.00
46_A	49_L	0.937	1.00
328_V	333_L	0.936	1.00
341_R	377_D	0.935	1.00
411_I	417_S	0.933	1.00
331_A	358_E	0.932	1.00
337_V	373_G	0.931	1.00
243_L	247_R	0.929	1.00
46_A	50_A	0.929	1.00
338_S	342_T	0.926	1.00
39_E	43_I	0.925	1.00
244_E	248_V	0.924	1.00
275_R	279_E	0.923	1.00
429_A	432_Q	0.919	1.00
369_E	373_G	0.918	1.00
330_V	402_L	0.915	1.00
221_T	224_K	0.914	1.00
43_I	47_T	0.910	1.00
227_P	251_E	0.909	1.00
98_T	165_S	0.908	1.00
345_L	389_I	0.907	1.00
238_K	242_A	0.903	1.00
149_Y	167_G	0.902	1.00
107_D	111_K	0.898	1.00
310_T	367_L	0.898	1.00
370_Q	445_V	0.897	1.00
437_L	441_F	0.897	1.00
210_I	214_T	0.895	1.00
288_E	291_A	0.894	1.00
333_L	363_A	0.894	1.00
196_L	200_A	0.893	1.00
31_K	35_R	0.892	1.00
330_V	400_V	0.892	1.00
178_K	181_E	0.888	1.00
123_V	127_L	0.887	1.00
337_V	341_R	0.887	1.00
419_I	465_A	0.885	1.00
299_T	336_R	0.885	1.00
375_L	442_V	0.885	1.00
376_L	391_L	0.881	1.00
204_W	208_R	0.880	1.00
258_Q	422_R	0.877	1.00
396_D	468_R	0.877	1.00
297_I	301_N	0.875	1.00
254_N	257_E	0.875	1.00
350_I	383_T	0.873	1.00
79_F	83_I	0.870	1.00
382_F	409_S	0.869	1.00
214_T	217_A	0.869	1.00
124_W	128_R	0.869	1.00
411_I	457_N	0.869	1.00
420_F	443_S	0.868	1.00
273_A	276_G	0.868	1.00
153_P	160_L	0.864	1.00
306_A	310_T	0.860	1.00
56_D	60_G	0.858	1.00
412_P	426_L	0.854	1.00
334_F	391_L	0.854	1.00
266_E	270_P	0.853	1.00
42_L	46_A	0.852	1.00
323_V	448_L	0.851	1.00
121_N	125_L	0.851	1.00
325_L	363_A	0.850	1.00
301_N	305_Q	0.848	1.00
183_R	186_W	0.848	1.00
232_G	240_A	0.846	1.00
442_V	446_A	0.845	1.00
206_I	209_S	0.845	1.00
344_Q	377_D	0.844	1.00
267_L	304_M	0.843	1.00
144_E	148_M	0.840	1.00
265_H	374_N	0.839	1.00
125_L	129_G	0.838	1.00
227_P	247_R	0.835	1.00
210_I	213_L	0.834	1.00
217_A	243_L	0.834	1.00
413_D	458_V	0.829	1.00
410_G	463_V	0.825	1.00
329_D	359_V	0.825	1.00
314_Q	440_A	0.822	1.00
268_K	305_Q	0.819	1.00
335_R	339_E	0.818	1.00
201_G	205_W	0.817	1.00
334_F	372_L	0.814	1.00
277_A	297_I	0.812	1.00
241_Q	244_E	0.812	1.00
253_K	256_I	0.812	1.00
184_I	187_A	0.810	1.00
220_V	246_M	0.810	1.00
292_R	295_D	0.808	1.00
203_V	206_I	0.805	1.00
376_L	389_I	0.804	1.00
28_K	31_K	0.803	1.00
182_R	186_W	0.803	1.00
405_L	458_V	0.802	1.00
216_Y	228_L	0.799	1.00
371_A	449_F	0.796	1.00
375_L	467_L	0.794	1.00
39_E	42_L	0.792	1.00
239_L	242_A	0.792	1.00
104_V	107_D	0.791	1.00
413_D	457_N	0.790	1.00
413_D	417_S	0.790	1.00
179_R	182_R	0.789	1.00
269_S	273_A	0.786	1.00
139_N	143_P	0.785	1.00
454_T	467_L	0.785	1.00
263_L	311_L	0.779	1.00
268_K	309_E	0.777	1.00
79_F	82_N	0.775	1.00
209_S	214_T	0.774	1.00
227_P	244_E	0.773	1.00
325_L	450_N	0.772	1.00
217_A	242_A	0.771	1.00
147_V	151_A	0.771	1.00
339_E	342_T	0.769	1.00
271_L	308_V	0.767	1.00
373_G	377_D	0.763	1.00
238_K	241_Q	0.762	1.00
108_S	111_K	0.758	1.00
140_P	143_P	0.756	1.00
391_L	404_V	0.754	1.00
142_D	145_S	0.753	1.00
174_A	178_K	0.752	1.00
259_Y	266_E	0.747	1.00
406_D	409_S	0.745	1.00
335_R	338_S	0.745	1.00
350_I	354_V	0.745	1.00
366_A	369_E	0.744	1.00
83_I	87_N	0.744	1.00
356_P	359_V	0.742	1.00
99_D	105_L	0.742	1.00
195_A	199_G	0.741	1.00
107_D	110_N	0.741	1.00
345_L	352_L	0.740	1.00
282_R	294_T	0.735	1.00
350_I	380_I	0.735	1.00
383_T	386_S	0.735	1.00
313_R	367_L	0.734	1.00
338_S	352_L	0.734	1.00
57_L	61_D	0.734	1.00
50_A	54_R	0.734	1.00
219_S	223_N	0.733	1.00
346_A	349_K	0.733	1.00
401_T	454_T	0.732	1.00
87_N	106_F	0.732	1.00
425_S	434_S	0.732	1.00
77_R	81_A	0.731	1.00
23_L	27_V	0.729	1.00
141_A	145_S	0.728	1.00
153_P	163_V	0.727	1.00
343_V	347_E	0.727	1.00
313_R	370_Q	0.725	1.00
77_R	80_R	0.725	1.00
357_T	395_V	0.724	1.00
257_E	318_E	0.723	1.00
251_E	254_N	0.723	1.00
393_A	402_L	0.723	1.00
273_A	296_N	0.722	1.00
451_G	467_L	0.722	1.00
293_F	297_I	0.721	1.00
289_V	293_F	0.721	1.00
295_D	298_L	0.720	1.00
183_R	187_A	0.716	1.00
444_E	448_L	0.716	1.00
215_R	219_S	0.716	1.00
416_L	456_R	0.714	1.00
379_A	404_V	0.707	1.00
296_N	299_T	0.706	1.00
341_R	380_I	0.706	1.00
60_G	64_H	0.706	1.00
266_E	269_S	0.705	1.00
345_L	348_K	0.705	1.00
211_A	215_R	0.705	1.00
116_D	119_R	0.704	1.00
150_V	153_P	0.704	1.00
233_S	239_L	0.703	1.00
45_T	48_L	0.701	1.00
37_A	41_T	0.701	1.00
229_P	244_E	0.699	1.00
209_S	213_L	0.699	1.00
324_V	364_E	0.693	1.00
173_M	176_V	0.692	1.00
235_E	238_K	0.688	1.00
359_V	393_A	0.687	1.00
93_Y	96_Y	0.686	1.00
451_G	470_H	0.686	1.00
355_T	394_E	0.685	1.00
265_H	269_S	0.685	1.00
367_L	449_F	0.685	1.00
153_P	162_G	0.683	1.00
28_K	32_P	0.683	1.00
54_R	58_L	0.683	1.00
223_N	226_V	0.681	1.00
403_K	456_R	0.680	1.00
303_R	369_E	0.680	1.00
208_R	212_R	0.678	1.00
272_A	276_G	0.677	1.00
39_E	148_M	0.676	1.00
234_S	238_K	0.674	1.00
151_A	165_S	0.674	1.00
122_D	125_L	0.673	1.00
57_L	60_G	0.673	1.00
280_I	293_F	0.672	1.00
310_T	370_Q	0.672	1.00
277_A	300_Q	0.670	1.00
381_D	425_S	0.670	1.00
147_V	167_G	0.668	1.00
349_K	386_S	0.667	1.00
56_D	59_S	0.666	1.00
214_T	242_A	0.664	1.00
188_S	192_L	0.664	1.00
212_R	215_R	0.663	1.00
349_K	385_E	0.661	1.00
230_D	234_S	0.660	1.00
219_S	222_D	0.657	1.00
20_W	24_A	0.656	1.00
40_G	43_I	0.655	1.00
35_R	39_E	0.653	1.00
359_V	362_A	0.653	1.00
262_A	266_E	0.653	1.00
419_I	440_A	0.653	1.00
228_L	240_A	0.652	1.00
345_L	350_I	0.651	1.00
218_D	238_K	0.650	1.00
367_L	371_A	0.649	1.00
27_V	181_E	0.649	1.00
241_Q	245_S	0.648	1.00
172_A	175_P	0.648	1.00
200_A	204_W	0.648	1.00
149_Y	152_A	0.647	1.00
290_V	293_F	0.646	1.00
260_V	264_T	0.645	1.00
416_L	465_A	0.645	1.00
266_E	307_L	0.645	1.00
234_S	240_A	0.644	1.00
393_A	400_V	0.643	1.00
130_Q	134_R	0.642	1.00
38_T	41_T	0.641	1.00
58_L	61_D	0.640	1.00
269_S	276_G	0.639	1.00
205_W	208_R	0.639	1.00
119_R	122_D	0.638	1.00
218_D	222_D	0.638	1.00
230_D	241_Q	0.638	1.00
229_P	233_S	0.637	1.00
156_D	161_I	0.636	1.00
304_M	308_V	0.635	1.00
37_A	40_G	0.633	1.00
185_L	189_A	0.633	1.00
331_A	359_V	0.633	1.00
175_P	179_R	0.633	1.00
81_A	85_G	0.633	1.00
260_V	263_L	0.633	1.00
94_H	108_S	0.632	1.00
216_Y	226_V	0.631	1.00
395_V	400_V	0.631	1.00
425_S	433_K	0.628	1.00
117_Y	123_V	0.628	1.00
81_A	84_G	0.626	1.00
145_S	148_M	0.626	1.00
221_T	245_S	0.626	1.00
348_K	380_I	0.625	1.00
328_V	362_A	0.623	1.00
429_A	433_K	0.623	1.00
302_A	305_Q	0.622	1.00
328_V	368_L	0.621	1.00
146_S	149_Y	0.620	1.00
409_S	463_V	0.620	1.00
14_L	18_A	0.619	1.00
139_N	142_D	0.619	1.00
186_W	190_I	0.618	1.00
441_F	445_V	0.617	1.00
96_Y	167_G	0.617	1.00
267_L	270_P	0.616	1.00
312_L	316_R	0.615	1.00
281_L	293_F	0.614	1.00
338_S	391_L	0.613	1.00
232_G	236_L	0.613	1.00
443_S	452_E	0.613	1.00
281_L	297_I	0.613	1.00
91_N	94_H	0.612	1.00
351_T	354_V	0.611	1.00
332_A	335_R	0.610	1.00
97_M	105_L	0.609	1.00
230_D	240_A	0.608	1.00
97_M	162_G	0.607	1.00
328_V	365_P	0.605	1.00
129_G	132_G	0.605	1.00
126_T	129_G	0.604	1.00
38_T	42_L	0.604	1.00
249_K	252_G	0.604	1.00
358_E	361_V	0.602	1.00
323_V	449_F	0.602	1.00
244_E	250_L	0.599	1.00
163_V	167_G	0.599	1.00
399_H	470_H	0.598	1.00
84_G	87_N	0.597	1.00
148_M	168_K	0.595	1.00
304_M	312_L	0.595	1.00
120_W	123_V	0.594	1.00
333_L	368_L	0.593	1.00
255_Y	258_Q	0.593	1.00
125_L	128_R	0.592	1.00
410_G	462_G	0.590	1.00
370_Q	373_G	0.588	1.00
389_I	404_V	0.588	1.00
311_L	423_F	0.587	1.00
162_G	166_V	0.585	1.00
361_V	400_V	0.584	1.00
83_I	86_I	0.583	1.00
280_I	284_G	0.583	1.00
415_A	428_R	0.583	1.00
100_A	160_L	0.582	1.00
344_Q	348_K	0.581	1.00
381_D	433_K	0.580	1.00
141_A	144_E	0.580	1.00
139_N	145_S	0.579	1.00
82_N	87_N	0.578	1.00
384_P	387_G	0.577	1.00
36_R	39_E	0.577	1.00
266_E	441_F	0.576	1.00
343_V	346_A	0.575	1.00
90_R	93_Y	0.574	1.00
375_L	446_A	0.574	1.00
331_A	357_T	0.573	1.00
140_P	144_E	0.573	1.00
284_G	293_F	0.573	1.00
189_A	193_G	0.572	1.00
60_G	63_T	0.572	1.00
105_L	162_G	0.570	1.00
279_E	282_R	0.570	1.00
35_R	38_T	0.570	1.00
27_V	31_K	0.568	1.00
218_D	221_T	0.566	1.00
140_P	147_V	0.564	1.00
332_A	365_P	0.563	1.00
99_D	102_G	0.563	1.00
130_Q	133_A	0.562	1.00
314_Q	444_E	0.562	1.00
333_L	369_E	0.561	1.00
259_Y	264_T	0.561	1.00
208_R	211_A	0.560	1.00
131_Y	135_S	0.558	1.00
120_W	124_W	0.558	1.00
381_D	434_S	0.557	1.00
41_T	44_D	0.557	1.00
213_L	216_Y	0.556	1.00
96_Y	111_K	0.555	1.00
294_T	298_L	0.555	1.00
91_N	95_V	0.554	1.00
148_M	151_A	0.554	1.00
116_D	120_W	0.554	1.00
155_M	158_S	0.554	1.00
155_M	162_G	0.553	1.00
330_V	361_V	0.552	1.00
104_V	108_S	0.552	1.00
428_R	432_Q	0.551	1.00
82_N	85_G	0.551	1.00
417_S	421_E	0.550	1.00
305_Q	308_V	0.549	1.00
272_A	275_R	0.549	1.00
440_A	444_E	0.549	1.00
212_R	216_Y	0.547	1.00
334_F	354_V	0.547	1.00
142_D	146_S	0.547	1.00
348_K	383_T	0.547	1.00
15_V	18_A	0.547	1.00
41_T	45_T	0.546	1.00
412_P	416_L	0.546	1.00
245_S	248_V	0.546	1.00
314_Q	318_E	0.545	1.00
388_C	405_L	0.543	1.00
405_L	460_E	0.542	1.00
148_M	173_M	0.542	1.00
300_Q	340_A	0.542	1.00
300_Q	304_M	0.540	1.00
411_I	465_A	0.540	1.00
216_Y	219_S	0.539	1.00
162_G	165_S	0.538	1.00
98_T	151_A	0.537	1.00
274_I	278_A	0.536	1.00
40_G	44_D	0.535	1.00
149_Y	165_S	0.535	1.00
82_N	86_I	0.534	1.00
11_Y	199_G	0.534	1.00
230_D	233_S	0.533	1.00
228_L	244_E	0.533	1.00
117_Y	120_W	0.533	1.00
59_S	62_P	0.531	1.00
266_E	300_Q	0.531	1.00
292_R	339_E	0.530	1.00
151_A	154_I	0.530	1.00
147_V	150_V	0.529	1.00
202_M	206_I	0.529	1.00
264_T	270_P	0.528	1.00
345_L	349_K	0.528	1.00
302_A	306_A	0.528	1.00
161_I	165_S	0.527	1.00
181_E	185_L	0.524	1.00
261_Y	264_T	0.524	1.00
97_M	164_L	0.524	1.00
51_E	55_P	0.524	1.00
446_A	452_E	0.522	1.00
24_A	27_V	0.522	1.00
126_T	130_Q	0.521	1.00
259_Y	312_L	0.520	1.00
368_L	372_L	0.517	1.00
36_R	40_G	0.516	1.00
264_T	268_K	0.514	1.00
215_R	218_D	0.513	1.00
121_N	124_W	0.512	1.00
177_I	180_S	0.512	1.00
230_D	237_R	0.511	1.00
395_V	399_H	0.510	1.00
390_T	393_A	0.510	1.00
49_L	52_L	0.509	1.00
331_A	354_V	0.509	1.00
384_P	407_T	0.507	1.00
94_H	111_K	0.507	1.00
268_K	312_L	0.507	1.00
381_D	427_P	0.506	1.00
453_V	465_A	0.505	1.00
267_L	308_V	0.505	1.00
299_T	302_A	0.505	1.00
78_P	82_N	0.503	1.00
376_L	380_I	0.503	1.00
112_A	116_D	0.501	1.00
179_R	183_R	0.501	1.00
33_G	37_A	0.501	1.00
268_K	304_M	0.500	1.00
210_I	236_L	0.500	1.00
259_Y	423_F	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4i5sA	2	0.5654	100	0.382	Contact Map
4bixA	2	0.4768	100	0.419	Contact Map
4ctiA	2	0.4768	100	0.435	Contact Map
4gczA	2	0.7384	100	0.461	Contact Map
3a0rA	2	0.692	100	0.464	Contact Map
4q20A	2	0.4789	100	0.485	Contact Map
4mpcA	2	0.616	100	0.487	Contact Map
3d36A	2	0.4641	100	0.491	Contact Map
3jz3A	2	0.3333	100	0.492	Contact Map
2q8gA	2	0.6245	100	0.495	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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