SPPA - ECOLI - GREMLIN Contacts

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SPPA - Protease 4

UniProt:	P08395	Sequences: MRTLWRFIAGFFKWTWRLLNFVREMVLNLFFIFLVLVGVGIWMQVSGGDSKETASRGALLLDISGVIVDKPDSSQRFSKLSRQLLGASSDRLQENSLFDIVNTIRQAKDDRNITGIVMDLKNFAGGDQPSMQYIGKALKEFRDSGKPVYAVGENYSQGQYYLASFANKIWLSPQGVVDLHGFATNGLYYKSLLDKLKVSTHVFRVGTYKSAVEPFIRDDMSPAAREADSRWIGELWQNYLNTVAANRQIPAEQVFPGAQGLLEGLTKTGGDTAKYALENKLVDALASSAEIEKALTKEFGWSKTDKNYRAISYYDYALKTPADTGDSIGVVFANGAIMDGEETQGNVGGDTTAAQIRDARLDPKVKAIVLRVNSPGGSVTASEVIRAELAAARAAGKPVVVSMGGMAASGGYWISTPANYIVANPSTLTGSIGIFGVITTVENSLDSIGVHTDGVSTSPLADVSITRALPPEAQLMMQLSIENGYKRFITLVADARHSTPEQIDKIAQGHVWTGQDAKANGLVDSLGDFDDAVAKAAELAKVKQWHLEYYVDEPTFFDKVMDNMSGSVRAMLPDAFQAMLPAPLASVASTVKSESDKLAAFNDPQNRYAFCLTCANMR	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10968
Length:	618 (541)
Sequences:	1291 (972)
Seq/√Len:	41.8

ECOLI - SPPA

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
368_I	392_A	6.518	1.00
434_I	484_G	6.250	1.00
372_V	415_S	5.562	1.00
191_S	218_D	4.786	1.00
498_S	503_I	4.709	1.00
400_V	539_L	4.585	1.00
105_R	140_E	3.647	1.00
104_I	116_I	3.505	1.00
357_R	388_E	3.482	1.00
422_V	535_K	3.350	1.00
138_L	148_V	3.277	1.00
420_Y	535_K	3.203	1.00
289_A	387_A	3.182	1.00
492_V	503_I	2.933	1.00
108_K	140_E	2.901	1.00
367_A	536_A	2.900	1.00
425_P	526_L	2.888	1.00
127_D	405_G	2.846	1.00
190_K	194_D	2.845	1.00
331_V	359_A	2.818	1.00
489_I	500_P	2.782	1.00
401_V	418_A	2.767	1.00
356_I	389_L	2.745	1.00
100_I	134_I	2.673	1.00
420_Y	525_S	2.660	1.00
504_D	508_Q	2.617	1.00
385_I	414_I	2.576	1.00
116_I	141_F	2.569	1.00
356_I	392_A	2.542	1.00
229_S	233_G	2.537	1.00
340_G	348_G	2.529	1.00
416_T	495_A	2.516	1.00
234_E	513_T	2.513	1.00
230_R	516_D	2.504	1.00
499_T	502_Q	2.498	1.00
208_Y	226_E	2.484	1.00
349_G	353_A	2.478	1.00
207_T	508_Q	2.454	1.00
486_K	500_P	2.436	1.00
282_V	285_L	2.406	1.00
339_D	349_G	2.371	1.00
168_K	284_A	2.352	1.00
536_A	540_A	2.317	1.00
191_S	451_H	2.250	1.00
360_R	388_E	2.230	1.00
370_L	389_L	2.209	1.00
336_A	375_P	2.186	1.00
110_D	316_Y	2.184	1.00
202_V	216_I	2.174	1.00
334_N	373_N	2.168	1.00
502_Q	505_K	2.127	0.99
333_A	347_V	2.119	0.99
360_R	391_A	2.117	0.99
489_I	504_D	2.109	0.99
389_L	399_V	2.077	0.99
200_T	439_T	2.076	0.99
535_K	539_L	2.075	0.99
506_I	520_N	2.068	0.99
329_G	365_V	2.024	0.99
333_A	414_I	1.993	0.99
467_R	473_A	1.989	0.99
67_I	134_I	1.985	0.99
504_D	507_A	1.958	0.99
115_G	147_P	1.946	0.99
406_M	428_L	1.941	0.99
213_E	221_S	1.937	0.99
356_I	368_I	1.928	0.99
333_A	352_T	1.886	0.99
388_E	391_A	1.881	0.99
434_I	481_I	1.875	0.99
23_R	28_N	1.850	0.98
16_W	20_N	1.837	0.98
456_S	462_D	1.827	0.98
17_R	20_N	1.820	0.98
419_N	539_L	1.817	0.98
170_W	286_A	1.801	0.98
58_A	117_V	1.780	0.98
197_K	447_S	1.775	0.98
135_G	165_F	1.771	0.98
170_W	284_A	1.759	0.98
326_D	366_K	1.747	0.98
219_D	222_P	1.745	0.98
234_E	516_D	1.745	0.98
535_K	538_E	1.744	0.98
25_M	28_N	1.742	0.98
212_V	435_F	1.737	0.98
188_Y	220_M	1.734	0.98
54_A	57_G	1.732	0.98
386_R	413_W	1.704	0.97
117_V	291_I	1.701	0.97
528_D	531_D	1.685	0.97
116_I	138_L	1.684	0.97
422_V	531_D	1.683	0.97
360_R	392_A	1.682	0.97
513_T	516_D	1.679	0.97
515_Q	518_K	1.672	0.97
489_I	493_A	1.665	0.97
150_A	166_A	1.658	0.97
371_R	402_S	1.650	0.97
490_T	494_D	1.625	0.96
523_V	526_L	1.612	0.96
487_R	491_L	1.610	0.96
516_D	519_A	1.608	0.96
416_T	492_V	1.604	0.96
274_K	278_E	1.602	0.96
369_V	536_A	1.602	0.96
203_F	474_Q	1.581	0.96
387_A	391_A	1.581	0.96
459_P	472_E	1.572	0.96
171_L	285_L	1.569	0.95
525_S	531_D	1.560	0.95
201_H	474_Q	1.553	0.95
18_L	23_R	1.548	0.95
130_S	373_N	1.537	0.95
14_W	20_N	1.536	0.95
135_G	246_N	1.536	0.95
331_V	356_I	1.523	0.95
368_I	397_K	1.522	0.95
369_V	529_F	1.515	0.95
164_S	246_N	1.505	0.94
481_I	484_G	1.498	0.94
182_F	232_I	1.488	0.94
21_F	25_M	1.484	0.94
108_K	144_S	1.481	0.94
153_E	288_S	1.469	0.94
210_S	220_M	1.440	0.93
525_S	535_K	1.413	0.92
348_G	351_T	1.407	0.92
347_V	352_T	1.384	0.91
53_T	311_I	1.380	0.91
537_A	545_W	1.369	0.91
244_A	249_I	1.364	0.91
138_L	165_F	1.359	0.91
555_T	558_D	1.355	0.90
353_A	388_E	1.354	0.90
493_A	498_S	1.353	0.90
20_N	24_E	1.331	0.90
152_G	155_Y	1.330	0.90
359_A	368_I	1.328	0.90
130_S	405_G	1.323	0.89
132_Q	238_N	1.321	0.89
139_K	165_F	1.308	0.89
367_A	540_A	1.307	0.89
416_T	489_I	1.307	0.89
400_V	536_A	1.303	0.89
253_Q	256_P	1.299	0.88
490_T	500_P	1.297	0.88
32_I	36_L	1.296	0.88
56_R	114_T	1.295	0.88
255_F	458_S	1.293	0.88
391_A	394_A	1.282	0.88
16_W	19_L	1.280	0.88
342_E	351_T	1.269	0.87
161_Y	242_T	1.268	0.87
277_L	282_V	1.266	0.87
28_N	31_F	1.264	0.87
400_V	532_A	1.260	0.87
189_Y	214_P	1.253	0.87
28_N	32_I	1.253	0.87
67_I	100_I	1.244	0.86
353_A	384_V	1.242	0.86
187_L	452_T	1.242	0.86
518_K	525_S	1.241	0.86
199_S	443_N	1.240	0.86
57_G	113_I	1.239	0.86
355_Q	359_A	1.236	0.86
347_V	414_I	1.224	0.85
294_A	298_E	1.224	0.85
65_G	123_F	1.222	0.85
443_N	447_S	1.220	0.85
486_K	504_D	1.220	0.85
383_E	491_L	1.213	0.85
218_D	451_H	1.208	0.85
286_A	294_A	1.206	0.84
131_M	162_L	1.203	0.84
498_S	502_Q	1.203	0.84
231_W	511_V	1.202	0.84
222_P	229_S	1.195	0.84
356_I	399_V	1.194	0.84
205_V	482_E	1.192	0.84
53_T	57_G	1.192	0.84
365_V	397_K	1.190	0.84
327_S	362_D	1.182	0.83
441_V	465_I	1.176	0.83
55_S	112_N	1.175	0.83
359_A	392_A	1.173	0.83
60_L	310_A	1.172	0.83
111_R	363_P	1.170	0.83
236_W	458_S	1.167	0.82
471_P	474_Q	1.167	0.82
339_D	378_S	1.165	0.82
220_M	453_D	1.165	0.82
199_S	440_T	1.164	0.82
168_K	294_A	1.163	0.82
250_P	253_Q	1.161	0.82
202_V	212_V	1.161	0.82
373_N	405_G	1.159	0.82
173_P	285_L	1.157	0.82
372_V	385_I	1.155	0.82
267_K	459_P	1.154	0.82
400_V	535_K	1.153	0.82
34_L	38_G	1.147	0.81
286_A	290_E	1.142	0.81
420_Y	539_L	1.140	0.81
220_M	225_R	1.140	0.81
499_T	504_D	1.138	0.81
228_D	231_W	1.130	0.80
182_F	239_Y	1.124	0.80
461_A	468_A	1.123	0.80
403_M	427_T	1.113	0.79
329_G	551_V	1.112	0.79
169_I	283_D	1.109	0.79
500_P	504_D	1.109	0.79
369_V	537_A	1.105	0.79
198_V	444_S	1.104	0.79
217_R	221_S	1.102	0.79
372_V	406_M	1.090	0.78
531_D	534_A	1.087	0.78
240_L	254_V	1.082	0.77
224_A	227_A	1.081	0.77
157_Q	180_H	1.078	0.77
13_K	16_W	1.076	0.77
506_I	512_W	1.068	0.76
20_N	23_R	1.068	0.76
141_F	144_S	1.067	0.76
501_E	505_K	1.061	0.76
370_L	401_V	1.054	0.75
501_E	504_D	1.054	0.75
393_R	495_A	1.048	0.75
400_V	540_A	1.043	0.75
75_Q	78_S	1.041	0.75
423_A	523_V	1.039	0.74
352_T	370_L	1.039	0.74
445_L	452_T	1.037	0.74
416_T	503_I	1.037	0.74
20_N	28_N	1.035	0.74
137_A	140_E	1.033	0.74
286_A	291_I	1.029	0.74
139_K	245_A	1.023	0.73
330_V	529_F	1.020	0.73
205_V	434_I	1.016	0.73
390_A	394_A	1.011	0.72
393_R	419_N	1.008	0.72
147_P	167_N	1.006	0.72
529_F	533_V	1.006	0.72
295_L	299_F	1.006	0.72
443_N	446_D	1.005	0.72
217_R	223_A	1.004	0.72
556_F	560_V	1.002	0.72
289_A	391_A	1.000	0.71
165_F	246_N	0.999	0.71
554_P	558_D	0.995	0.71
183_A	456_S	0.993	0.71
290_E	387_A	0.992	0.71
240_L	255_F	0.983	0.70
284_A	290_E	0.981	0.70
212_V	216_I	0.979	0.70
104_I	138_L	0.978	0.70
196_L	444_S	0.972	0.69
227_A	510_H	0.971	0.69
192_L	196_L	0.970	0.69
532_A	536_A	0.967	0.69
182_F	235_L	0.966	0.69
357_R	361_L	0.965	0.69
205_V	478_Q	0.964	0.69
332_F	549_Y	0.958	0.68
132_Q	242_T	0.956	0.68
193_L	200_T	0.955	0.68
33_F	37_V	0.951	0.68
552_D	558_D	0.949	0.67
390_A	417_P	0.949	0.67
478_Q	482_E	0.948	0.67
133_Y	424_N	0.947	0.67
338_M	346_N	0.947	0.67
194_D	218_D	0.940	0.67
357_R	391_A	0.939	0.67
142_R	167_N	0.939	0.67
197_K	444_S	0.938	0.67
368_I	399_V	0.937	0.66
342_E	348_G	0.937	0.66
206_G	213_E	0.936	0.66
172_S	384_V	0.932	0.66
190_K	218_D	0.932	0.66
105_R	137_A	0.928	0.66
240_L	251_A	0.928	0.66
530_D	534_A	0.920	0.65
104_I	141_F	0.919	0.65
403_M	423_A	0.919	0.65
370_L	414_I	0.919	0.65
489_I	492_V	0.919	0.65
331_V	389_L	0.918	0.65
62_D	119_D	0.917	0.65
67_I	97_L	0.917	0.65
149_Y	291_I	0.917	0.65
379_V	413_W	0.916	0.65
244_A	254_V	0.916	0.65
337_I	382_S	0.915	0.65
206_G	508_Q	0.914	0.64
207_T	223_A	0.913	0.64
202_V	437_V	0.912	0.64
225_R	229_S	0.911	0.64
533_V	547_L	0.908	0.64
383_E	487_R	0.908	0.64
460_L	473_A	0.907	0.64
422_V	526_L	0.905	0.64
436_G	477_M	0.904	0.64
331_V	355_Q	0.901	0.63
118_M	166_A	0.901	0.63
275_Y	279_N	0.900	0.63
215_F	437_V	0.898	0.63
379_V	484_G	0.893	0.63
148_V	166_A	0.892	0.63
441_V	444_S	0.891	0.62
276_A	348_G	0.891	0.62
518_K	526_L	0.890	0.62
102_N	106_Q	0.888	0.62
386_R	491_L	0.883	0.62
489_I	503_I	0.881	0.62
59_L	107_A	0.878	0.61
372_V	375_P	0.875	0.61
352_T	355_Q	0.869	0.61
58_A	115_G	0.869	0.61
28_N	36_L	0.868	0.60
277_L	284_A	0.867	0.60
554_P	562_D	0.867	0.60
225_R	453_D	0.866	0.60
293_K	303_K	0.866	0.60
59_L	316_Y	0.865	0.60
240_L	244_A	0.865	0.60
97_L	101_V	0.865	0.60
171_L	175_G	0.862	0.60
502_Q	506_I	0.861	0.60
253_Q	280_K	0.861	0.60
333_A	370_L	0.859	0.60
413_W	491_L	0.858	0.60
338_M	381_A	0.858	0.60
13_K	17_R	0.858	0.60
127_D	182_F	0.857	0.59
388_E	392_A	0.856	0.59
136_K	424_N	0.855	0.59
518_K	523_V	0.855	0.59
98_F	549_Y	0.854	0.59
280_K	541_K	0.851	0.59
231_W	428_L	0.849	0.59
60_L	308_Y	0.849	0.59
140_E	143_D	0.849	0.59
212_V	482_E	0.842	0.58
224_A	228_D	0.838	0.58
21_F	24_E	0.835	0.57
188_Y	224_A	0.835	0.57
136_K	531_D	0.834	0.57
489_I	508_Q	0.833	0.57
19_L	28_N	0.831	0.57
372_V	404_G	0.830	0.57
445_L	466_T	0.829	0.57
211_A	375_P	0.827	0.57
393_R	418_A	0.827	0.57
497_H	541_K	0.825	0.57
328_I	547_L	0.825	0.57
130_S	404_G	0.825	0.57
30_F	35_V	0.824	0.56
139_K	143_D	0.821	0.56
110_D	359_A	0.821	0.56
177_V	282_V	0.820	0.56
148_V	167_N	0.820	0.56
390_A	494_D	0.819	0.56
118_M	162_L	0.819	0.56
340_G	351_T	0.818	0.56
197_K	200_T	0.817	0.56
211_A	435_F	0.816	0.56
372_V	414_I	0.816	0.56
22_V	26_V	0.815	0.56
244_A	252_E	0.815	0.56
297_K	541_K	0.808	0.55
171_L	282_V	0.808	0.55
386_R	495_A	0.808	0.55
331_V	368_I	0.807	0.55
275_Y	278_E	0.807	0.55
210_S	224_A	0.807	0.55
325_G	546_H	0.798	0.54
249_I	254_V	0.798	0.54
248_Q	497_H	0.796	0.54
422_V	525_S	0.796	0.54
384_V	388_E	0.795	0.54
198_V	331_V	0.795	0.54
331_V	392_A	0.795	0.54
417_P	495_A	0.789	0.53
135_G	161_Y	0.788	0.53
198_V	542_V	0.788	0.53
211_A	215_F	0.788	0.53
16_W	21_F	0.787	0.53
155_Y	175_G	0.786	0.53
149_Y	298_E	0.785	0.53
237_Q	515_Q	0.783	0.53
77_F	81_S	0.782	0.53
392_A	396_G	0.781	0.52
249_I	552_D	0.779	0.52
149_Y	446_D	0.779	0.52
103_T	317_A	0.778	0.52
529_F	547_L	0.778	0.52
205_V	484_G	0.778	0.52
470_P	473_A	0.776	0.52
341_E	354_A	0.776	0.52
279_N	477_M	0.774	0.52
204_R	212_V	0.774	0.52
498_S	521_G	0.774	0.52
327_S	546_H	0.770	0.51
213_E	217_R	0.769	0.51
289_A	388_E	0.767	0.51
359_A	397_K	0.764	0.51
503_I	506_I	0.764	0.51
17_R	24_E	0.764	0.51
492_V	506_I	0.763	0.51
534_A	538_E	0.762	0.51
185_N	456_S	0.759	0.50
100_I	313_Y	0.758	0.50
191_S	194_D	0.757	0.50
213_E	224_A	0.756	0.50
101_V	137_A	0.756	0.50
37_V	144_S	0.756	0.50
446_D	451_H	0.754	0.50
285_L	291_I	0.752	0.50
189_Y	192_L	0.751	0.50
22_V	27_L	0.751	0.50
416_T	491_L	0.750	0.50
560_V	574_D	0.749	0.49
53_T	113_I	0.749	0.49
36_L	243_V	0.749	0.49
503_I	508_Q	0.748	0.49
196_L	448_I	0.748	0.49
138_L	166_A	0.748	0.49
311_I	316_Y	0.747	0.49
400_V	547_L	0.744	0.49
244_A	470_P	0.742	0.49
406_M	415_S	0.742	0.49
68_V	345_G	0.739	0.48
59_L	110_D	0.738	0.48
34_L	37_V	0.735	0.48
312_S	400_V	0.735	0.48
16_W	32_I	0.733	0.48
25_M	29_L	0.730	0.48
270_G	275_Y	0.730	0.48
356_I	361_L	0.730	0.48
234_E	515_Q	0.729	0.48
153_E	384_V	0.728	0.47
35_V	38_G	0.728	0.47
131_M	243_V	0.727	0.47
174_Q	487_R	0.726	0.47
172_S	379_V	0.726	0.47
362_D	397_K	0.724	0.47
23_R	31_F	0.724	0.47
532_A	540_A	0.722	0.47
294_A	297_K	0.720	0.47
19_L	25_M	0.718	0.47
341_E	348_G	0.716	0.46
378_S	411_G	0.715	0.46
18_L	28_N	0.715	0.46
32_I	35_V	0.715	0.46
330_V	549_Y	0.713	0.46
230_R	513_T	0.712	0.46
486_K	489_I	0.711	0.46
208_Y	385_I	0.710	0.46
274_K	277_L	0.706	0.45
489_I	499_T	0.700	0.45
486_K	490_T	0.700	0.45
108_K	143_D	0.699	0.45
245_A	297_K	0.698	0.45
244_A	472_E	0.698	0.45
352_T	414_I	0.697	0.45
58_A	299_F	0.697	0.45
100_I	328_I	0.696	0.44
203_F	469_L	0.696	0.44
357_R	360_R	0.694	0.44
61_L	104_I	0.693	0.44
75_Q	81_S	0.693	0.44
380_T	384_V	0.693	0.44
353_A	357_R	0.692	0.44
163_A	169_I	0.691	0.44
16_W	29_L	0.691	0.44
151_V	172_S	0.690	0.44
18_L	22_V	0.689	0.44
353_A	356_I	0.688	0.44
564_M	567_S	0.687	0.44
438_I	469_L	0.687	0.44
18_L	24_E	0.687	0.44
14_W	18_L	0.686	0.44
219_D	453_D	0.686	0.44
171_L	284_A	0.684	0.43
199_S	442_E	0.684	0.43
378_S	381_A	0.684	0.43
14_W	17_R	0.682	0.43
16_W	28_N	0.681	0.43
271_D	274_K	0.680	0.43
287_S	387_A	0.680	0.43
369_V	547_L	0.679	0.43
220_M	228_D	0.678	0.43
127_D	158_G	0.675	0.43
174_Q	413_W	0.674	0.42
233_G	280_K	0.674	0.42
203_F	478_Q	0.673	0.42
515_Q	519_A	0.673	0.42
338_M	348_G	0.671	0.42
236_W	457_T	0.671	0.42
215_F	336_A	0.670	0.42
132_Q	425_P	0.670	0.42
241_N	251_A	0.669	0.42
128_Q	235_L	0.669	0.42
69_D	371_R	0.669	0.42
348_G	381_A	0.668	0.42
327_S	548_E	0.668	0.42
19_L	31_F	0.667	0.42
559_K	563_N	0.667	0.42
211_A	216_I	0.664	0.42
333_A	411_G	0.663	0.41
188_Y	251_A	0.663	0.41
220_M	224_A	0.662	0.41
168_K	283_D	0.662	0.41
413_W	487_R	0.662	0.41
67_I	130_S	0.662	0.41
386_R	417_P	0.659	0.41
435_F	457_T	0.657	0.41
444_S	448_I	0.656	0.41
141_F	161_Y	0.654	0.41
268_T	275_Y	0.654	0.41
148_V	359_A	0.654	0.41
20_N	32_I	0.654	0.41
300_G	544_Q	0.654	0.41
280_K	497_H	0.653	0.41
333_A	389_L	0.652	0.40
349_G	381_A	0.651	0.40
123_F	510_H	0.651	0.40
161_Y	239_Y	0.650	0.40
403_M	526_L	0.646	0.40
13_K	21_F	0.646	0.40
558_D	561_M	0.644	0.40
244_A	250_P	0.644	0.40
557_F	560_V	0.644	0.40
311_I	314_Y	0.643	0.40
143_D	248_Q	0.642	0.40
125_G	130_S	0.640	0.39
331_V	348_G	0.640	0.39
347_V	375_P	0.639	0.39
380_T	383_E	0.639	0.39
203_F	482_E	0.637	0.39
275_Y	476_M	0.636	0.39
239_Y	243_V	0.635	0.39
557_F	561_M	0.635	0.39
98_F	134_I	0.635	0.39
242_T	246_N	0.634	0.39
347_V	351_T	0.634	0.39
361_L	513_T	0.633	0.39
242_T	393_R	0.632	0.39
142_R	165_F	0.632	0.39
454_G	462_D	0.631	0.39
233_G	457_T	0.631	0.39
379_V	417_P	0.631	0.39
367_A	400_V	0.630	0.38
62_D	404_G	0.630	0.38
14_W	23_R	0.628	0.38
16_W	23_R	0.628	0.38
129_P	133_Y	0.627	0.38
243_V	352_T	0.627	0.38
238_N	242_T	0.627	0.38
80_L	365_V	0.627	0.38
441_V	445_L	0.626	0.38
121_K	439_T	0.626	0.38
370_L	385_I	0.626	0.38
232_I	457_T	0.626	0.38
360_R	396_G	0.625	0.38
143_D	541_K	0.625	0.38
115_G	149_Y	0.625	0.38
372_V	401_V	0.624	0.38
328_I	506_I	0.622	0.38
241_N	245_A	0.622	0.38
151_V	197_K	0.622	0.38
284_A	294_A	0.621	0.38
192_L	328_I	0.620	0.38
352_T	356_I	0.619	0.38
338_M	342_E	0.619	0.38
134_I	138_L	0.618	0.37
133_Y	528_D	0.617	0.37
37_V	250_P	0.614	0.37
493_A	499_T	0.613	0.37
76_R	226_E	0.613	0.37
15_T	20_N	0.613	0.37
104_I	161_Y	0.612	0.37
265_L	268_T	0.612	0.37
403_M	429_T	0.611	0.37
355_Q	392_A	0.611	0.37
17_R	28_N	0.611	0.37
201_H	440_T	0.611	0.37
171_L	215_F	0.610	0.37
207_T	504_D	0.610	0.37
135_G	460_L	0.609	0.37
36_L	245_A	0.609	0.37
17_R	21_F	0.608	0.37
277_L	285_L	0.608	0.37
192_L	450_V	0.608	0.37
289_A	392_A	0.607	0.36
493_A	503_I	0.606	0.36
184_T	228_D	0.605	0.36
61_L	118_M	0.605	0.36
187_L	244_A	0.604	0.36
42_W	45_V	0.604	0.36
14_W	19_L	0.603	0.36
157_Q	457_T	0.601	0.36
16_W	25_M	0.601	0.36
160_Y	247_R	0.601	0.36
27_L	103_T	0.600	0.36
356_I	370_L	0.600	0.36
434_I	480_S	0.598	0.36
386_R	416_T	0.598	0.36
17_R	23_R	0.598	0.36
58_A	308_Y	0.598	0.36
187_L	192_L	0.598	0.36
237_Q	372_V	0.598	0.36
330_V	533_V	0.598	0.36
327_S	533_V	0.597	0.36
175_G	453_D	0.597	0.36
29_L	32_I	0.596	0.36
340_G	350_D	0.595	0.35
168_K	298_E	0.595	0.35
375_P	411_G	0.595	0.35
197_K	443_N	0.594	0.35
383_E	413_W	0.592	0.35
26_V	30_F	0.592	0.35
386_R	390_A	0.592	0.35
572_L	575_A	0.592	0.35
330_V	547_L	0.592	0.35
191_S	198_V	0.591	0.35
132_Q	424_N	0.590	0.35
133_Y	479_L	0.590	0.35
206_G	221_S	0.590	0.35
349_G	384_V	0.589	0.35
77_F	80_L	0.588	0.35
206_G	478_Q	0.587	0.35
32_I	39_V	0.586	0.35
427_T	523_V	0.585	0.35
14_W	24_E	0.585	0.35
47_G	75_Q	0.583	0.34
113_I	321_P	0.583	0.34
197_K	446_D	0.581	0.34
157_Q	236_W	0.580	0.34
307_N	502_Q	0.579	0.34
189_Y	215_F	0.579	0.34
413_W	416_T	0.578	0.34
62_D	65_G	0.578	0.34
235_L	239_Y	0.577	0.34
158_G	192_L	0.577	0.34
378_S	382_S	0.577	0.34
204_R	216_I	0.577	0.34
132_Q	161_Y	0.575	0.34
254_V	281_L	0.575	0.34
375_P	406_M	0.574	0.34
172_S	206_G	0.574	0.34
22_V	34_L	0.573	0.34
389_L	495_A	0.573	0.34
299_F	308_Y	0.573	0.34
497_H	543_K	0.573	0.34
559_K	566_G	0.573	0.34
170_W	294_A	0.572	0.33
471_P	525_S	0.571	0.33
353_A	389_L	0.571	0.33
227_A	373_N	0.570	0.33
68_V	94_E	0.569	0.33
516_D	520_N	0.568	0.33
570_A	573_P	0.568	0.33
383_E	492_V	0.567	0.33
186_G	224_A	0.567	0.33
214_P	478_Q	0.566	0.33
103_T	313_Y	0.566	0.33
347_V	379_V	0.566	0.33
127_D	406_M	0.566	0.33
143_D	225_R	0.566	0.33
230_R	233_G	0.565	0.33
464_S	516_D	0.565	0.33
363_P	394_A	0.565	0.33
291_I	295_L	0.564	0.33
292_E	357_R	0.564	0.33
436_G	481_I	0.563	0.33
350_D	353_A	0.562	0.33
325_G	364_K	0.562	0.33
276_A	340_G	0.561	0.33
200_T	507_A	0.560	0.32
210_S	454_G	0.560	0.32
143_D	519_A	0.560	0.32
327_S	364_K	0.559	0.32
375_P	401_V	0.559	0.32
95_N	100_I	0.558	0.32
29_L	33_F	0.557	0.32
133_Y	371_R	0.557	0.32
172_S	205_V	0.557	0.32
193_L	196_L	0.556	0.32
213_E	457_T	0.556	0.32
214_P	435_F	0.556	0.32
44_Q	441_V	0.554	0.32
400_V	419_N	0.554	0.32
532_A	539_L	0.554	0.32
139_K	382_S	0.554	0.32
22_V	25_M	0.553	0.32
396_G	399_V	0.553	0.32
249_I	256_P	0.553	0.32
313_Y	404_G	0.552	0.32
463_V	477_M	0.552	0.32
133_Y	530_D	0.552	0.32
240_L	458_S	0.551	0.32
136_K	139_K	0.551	0.32
323_D	450_V	0.551	0.32
79_K	100_I	0.550	0.32
174_Q	383_E	0.550	0.32
271_D	386_R	0.550	0.32
322_A	533_V	0.548	0.32
280_K	461_A	0.548	0.32
128_Q	405_G	0.548	0.32
139_K	142_R	0.547	0.31
400_V	463_V	0.547	0.31
27_L	36_L	0.547	0.31
18_L	27_L	0.546	0.31
278_E	538_E	0.546	0.31
21_F	28_N	0.545	0.31
177_V	276_A	0.545	0.31
163_A	386_R	0.544	0.31
501_E	519_A	0.544	0.31
352_T	385_I	0.544	0.31
35_V	148_V	0.544	0.31
301_W	306_K	0.544	0.31
300_G	543_K	0.543	0.31
222_P	448_I	0.543	0.31
307_N	310_A	0.542	0.31
341_E	350_D	0.542	0.31
196_L	445_L	0.542	0.31
277_L	406_M	0.542	0.31
135_G	242_T	0.541	0.31
220_M	454_G	0.541	0.31
216_I	482_E	0.538	0.31
26_V	282_V	0.538	0.31
129_P	491_L	0.538	0.31
179_L	269_G	0.537	0.31
254_V	545_W	0.536	0.31
185_N	428_L	0.536	0.31
213_E	537_A	0.535	0.30
212_V	457_T	0.535	0.30
71_P	96_S	0.534	0.30
252_E	560_V	0.533	0.30
147_P	413_W	0.532	0.30
462_D	467_R	0.531	0.30
13_K	24_E	0.531	0.30
248_Q	538_E	0.531	0.30
445_L	465_I	0.530	0.30
230_R	510_H	0.529	0.30
242_T	245_A	0.529	0.30
287_S	456_S	0.529	0.30
22_V	290_E	0.528	0.30
217_R	224_A	0.528	0.30
226_E	230_R	0.528	0.30
153_E	380_T	0.527	0.30
160_Y	403_M	0.525	0.30
53_T	112_N	0.525	0.30
16_W	24_E	0.525	0.30
287_S	413_W	0.525	0.30
30_F	572_L	0.525	0.30
132_Q	136_K	0.524	0.30
359_A	365_V	0.524	0.30
26_V	31_F	0.523	0.30
517_A	522_L	0.523	0.30
534_A	541_K	0.523	0.30
149_Y	284_A	0.522	0.29
191_S	195_K	0.522	0.29
413_W	435_F	0.520	0.29
203_F	477_M	0.519	0.29
69_D	404_G	0.519	0.29
136_K	528_D	0.518	0.29
241_N	544_Q	0.518	0.29
421_I	495_A	0.518	0.29
13_K	20_N	0.517	0.29
223_A	226_E	0.517	0.29
22_V	31_F	0.516	0.29
92_L	232_I	0.516	0.29
20_N	39_V	0.515	0.29
248_Q	542_V	0.515	0.29
568_V	571_M	0.515	0.29
527_G	532_A	0.514	0.29
178_D	375_P	0.514	0.29
156_S	241_N	0.514	0.29
554_P	561_M	0.513	0.29
397_K	418_A	0.513	0.29
436_G	483_N	0.513	0.29
131_M	158_G	0.512	0.29
469_L	474_Q	0.511	0.29
252_E	256_P	0.511	0.29
393_R	436_G	0.511	0.29
373_N	401_V	0.510	0.29
45_V	55_S	0.510	0.29
169_I	179_L	0.509	0.28
174_Q	379_V	0.509	0.28
202_V	205_V	0.508	0.28
361_L	481_I	0.506	0.28
187_L	464_S	0.506	0.28
201_H	442_E	0.506	0.28
313_Y	316_Y	0.505	0.28
219_D	451_H	0.505	0.28
196_L	208_Y	0.505	0.28
203_F	231_W	0.505	0.28
484_G	489_I	0.504	0.28
25_M	507_A	0.504	0.28
182_F	405_G	0.503	0.28
306_K	361_L	0.502	0.28
340_G	349_G	0.502	0.28
501_E	508_Q	0.501	0.28
297_K	543_K	0.501	0.28
27_L	33_F	0.501	0.28
325_G	544_Q	0.500	0.28

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3bf0A	3	0.7735	100	0.386	Contact Map
4kwbA	5	0.3851	100	0.773	Contact Map
3rstA	3	0.3625	100	0.784	Contact Map
3vivA	2	0.3269	100	0.84	Contact Map
4gm2A	3	0.2751	100	0.843	Contact Map
2f6iA	5	0.2913	100	0.854	Contact Map
4u0gA	4	0.3155	100	0.858	Contact Map
3p2lA	4	0.3042	100	0.859	Contact Map
2cbyA	3	0.2702	100	0.859	Contact Map
1yg6A	4	0.3074	100	0.863	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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