GREMLIN Database
RECB - RecBCD enzyme subunit RecB
UniProt: P08394 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG10824
Length: 1180 (1017)
Sequences: 3037 (2659)
Seq/√Len: 83.4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
576_I736_V6.8721.00
549_V751_L5.4611.00
58_E379_P5.2881.00
955_L1083_S4.9851.00
748_E810_V4.9291.00
170_R338_T4.8311.00
739_V749_Y4.6431.00
592_E686_D4.3711.00
757_I815_L4.1071.00
550_R734_H4.0301.00
525_Q528_D4.0281.00
601_Q712_S3.9291.00
342_E345_R3.8241.00
760_F764_E3.8031.00
761_R764_E3.7251.00
527_R531_Q3.6681.00
130_H354_M3.5561.00
71_E75_R3.5361.00
523_A574_L3.2941.00
526_I554_I3.2641.00
500_K503_L3.1451.00
499_M502_W3.1341.00
553_D750_P3.1231.00
451_P455_N3.1191.00
754_L815_L3.1071.00
55_T58_E3.0531.00
313_I317_L3.0431.00
525_Q753_W3.0161.00
540_L543_G3.0041.00
497_P502_W2.9781.00
530_L551_A2.9671.00
624_N627_D2.9601.00
525_Q814_S2.9501.00
343_K353_D2.9491.00
522_C755_P2.9091.00
136_M358_L2.9071.00
1071_R1124_H2.8321.00
1016_N1071_R2.8251.00
359_D395_R2.8141.00
830_D833_V2.7731.00
559_R798_D2.7621.00
760_F763_Q2.7601.00
125_A378_F2.7541.00
836_S839_G2.7221.00
163_A342_E2.7121.00
460_L806_L2.7101.00
836_S840_R2.6981.00
833_V836_S2.6851.00
83_L86_A2.6661.00
753_W814_S2.6081.00
571_L578_S2.6021.00
1070_F1079_L2.5711.00
528_D532_A2.5691.00
647_G667_A2.5591.00
524_A574_L2.5251.00
608_R611_T2.5121.00
421_A790_A2.4821.00
627_D637_A2.4721.00
136_M374_I2.4601.00
130_H352_D2.4211.00
520_Q574_L2.4181.00
1071_R1076_Y2.4111.00
648_Y667_A2.4011.00
374_I378_F2.3971.00
834_H838_L2.3701.00
66_E130_H2.3581.00
832_D836_S2.3551.00
592_E683_R2.3531.00
302_G313_I2.3341.00
349_L354_M2.3051.00
558_V738_I2.2941.00
342_E346_R2.2891.00
130_H355_L2.2861.00
838_L842_L2.2571.00
34_A76_I2.2541.00
830_D834_H2.2391.00
599_L615_A2.2361.00
381_A400_I2.2151.00
559_R801_L2.2141.00
983_E986_W2.2121.00
130_H137_L2.1901.00
564_A738_I2.1871.00
338_T341_R2.1791.00
215_D333_A2.1751.00
303_E307_H2.1751.00
1068_L1079_L2.1571.00
144_S361_A2.1521.00
596_M687_I2.1471.00
972_W975_E2.1361.00
435_S467_A2.1131.00
519_A523_A2.1091.00
830_D836_S2.1051.00
527_R574_L2.0961.00
291_Q313_I2.0731.00
837_A840_R2.0691.00
957_S961_D2.0691.00
79_N82_E2.0611.00
540_L547_R2.0461.00
14_P40_L2.0321.00
833_V837_A2.0281.00
492_K497_P2.0251.00
834_H842_L2.0211.00
291_Q295_E2.0171.00
837_A841_L2.0161.00
830_D835_Q2.0091.00
837_A842_L1.9981.00
130_H390_D1.9961.00
839_G843_Q1.9941.00
555_S749_Y1.9881.00
839_G842_L1.9831.00
314_D317_L1.9731.00
302_G306_R1.9691.00
255_R258_N1.9651.00
314_D318_A1.9551.00
520_Q570_A1.9451.00
949_A953_T1.9441.00
834_H841_L1.9431.00
833_V840_R1.9391.00
1103_Q1132_E1.9361.00
831_T834_H1.9341.00
836_S844_K1.9301.00
741_I805_A1.9141.00
832_D835_Q1.9051.00
310_F317_L1.9001.00
832_D837_A1.8981.00
833_V839_G1.8841.00
17_G439_A1.8841.00
22_E415_P1.8771.00
970_P974_R1.8721.00
1078_L1118_L1.8601.00
1072_H1127_A1.8391.00
363_R395_R1.8381.00
938_P942_P1.8281.00
551_A577_P1.8271.00
651_I663_A1.8231.00
258_N262_Q1.8221.00
306_R310_F1.8181.00
547_R553_D1.8091.00
665_M687_I1.8061.00
309_L313_I1.8041.00
835_Q839_G1.7991.00
526_I753_W1.7981.00
151_Q157_S1.7961.00
675_L684_L1.7901.00
651_I655_R1.7891.00
1001_P1004_E1.7851.00
549_V554_I1.7801.00
338_T342_E1.7781.00
313_I318_A1.7681.00
456_S806_L1.7551.00
1069_V1118_L1.7531.00
381_A401_W1.7511.00
496_Q502_W1.7481.00
984_S988_P1.7461.00
529_W753_W1.7411.00
754_L757_I1.7311.00
694_L707_L1.7221.00
499_M503_L1.7141.00
153_I348_E1.7141.00
522_C753_W1.7141.00
529_W814_S1.7041.00
37_Y76_I1.6951.00
125_A135_R1.6941.00
313_I316_L1.6871.00
834_H837_A1.6871.00
37_Y61_V1.6871.00
298_T313_I1.6811.00
292_R295_E1.6751.00
171_H334_E1.6741.00
254_R258_N1.6681.00
525_Q529_W1.6611.00
292_R296_D1.6541.00
1066_I1069_V1.6511.00
901_W904_T1.6501.00
31_F35_A1.6441.00
833_V844_K1.6441.00
159_L163_A1.6401.00
74_G78_S1.6261.00
418_A425_A1.6221.00
293_F296_D1.6191.00
421_A793_E1.6161.00
835_Q838_L1.6131.00
108_A111_A1.6111.00
496_Q499_M1.5871.00
497_P501_M1.5781.00
499_M505_E1.5781.00
918_Q921_M1.5701.00
833_V838_L1.5691.00
252_I255_R1.5661.00
1075_R1127_A1.5651.00
312_A316_L1.5611.00
497_P503_L1.5561.00
836_S843_Q1.5521.00
444_D479_K1.5441.00
602_A615_A1.5401.00
363_R399_R1.5361.00
258_N265_W1.5361.00
372_A375_R1.5351.00
80_I114_L1.5341.00
143_E370_L1.5341.00
858_E863_D1.5321.00
140_N373_A1.5311.00
529_W549_V1.5271.00
1115_T1119_H1.5230.99
40_L380_V1.5230.99
1025_L1117_A1.5220.99
497_P500_K1.5100.99
540_L544_D1.5050.99
134_Q138_N1.5040.99
570_A573_L1.5030.99
840_R844_K1.5020.99
450_A811_W1.4990.99
62_V129_I1.4990.99
160_R202_Q1.4980.99
858_E861_C1.4970.99
261_N264_K1.4960.99
261_N265_W1.4940.99
492_K499_M1.4940.99
498_A503_L1.4880.99
244_D248_E1.4810.99
598_W614_S1.4760.99
254_R265_W1.4720.99
341_R345_R1.4670.99
321_L324_R1.4620.99
476_I479_K1.4580.99
833_V842_L1.4580.99
137_L358_L1.4570.99
1108_D1112_Q1.4480.99
838_L841_L1.4460.99
221_R228_R1.4440.99
1116_L1120_R1.4430.99
229_I233_K1.4400.99
830_D837_A1.4390.99
751_L814_S1.4380.99
518_M816_G1.4160.99
306_R313_I1.4090.99
295_E298_T1.4080.99
533_G548_P1.4030.99
669_N672_E1.4020.99
308_P312_A1.4010.99
140_N143_E1.3960.99
41_L80_I1.3950.99
62_V397_F1.3910.99
1072_H1075_R1.3870.99
137_L354_M1.3860.99
77_R121_M1.3840.99
1010_S1072_H1.3810.99
835_Q840_R1.3740.99
663_A667_A1.3710.99
340_A357_R1.3690.99
166_D342_E1.3650.99
166_D338_T1.3610.99
291_Q298_T1.3590.99
296_D313_I1.3590.99
975_E979_L1.3590.99
834_H845_G1.3580.99
432_K436_E1.3570.99
571_L738_I1.3570.99
1070_F1077_Y1.3530.99
600_L661_L1.3530.99
959_F994_I1.3480.99
258_N261_N1.3480.99
158_L339_V1.3450.99
66_E134_Q1.3400.99
172_C190_P1.3400.99
617_A625_A1.3390.99
233_K236_W1.3330.99
150_Q349_L1.3320.99
770_D773_S1.3260.99
858_E864_D1.3260.99
265_W272_W1.3230.99
310_F314_D1.3180.99
355_L390_D1.3100.98
167_F334_E1.3030.98
938_P941_T1.3020.98
35_A79_N1.3010.98
1028_S1059_R1.2990.98
972_W976_K1.2960.98
334_E337_E1.2950.98
35_A39_R1.2940.98
834_H839_G1.2930.98
415_P430_Y1.2900.98
355_L392_Q1.2900.98
24_S27_T1.2890.98
57_E120_Q1.2890.98
462_S480_S1.2870.98
255_R262_Q1.2870.98
291_Q317_L1.2780.98
307_H310_F1.2780.98
18_E437_V1.2730.98
558_V755_P1.2710.98
191_Q194_L1.2690.98
293_F313_I1.2690.98
302_G305_P1.2660.98
934_V938_P1.2640.98
833_V845_G1.2540.98
835_Q841_L1.2520.98
303_E310_F1.2520.98
252_I258_N1.2510.98
37_Y56_V1.2500.98
39_R42_L1.2460.98
491_F500_K1.2440.98
130_H349_L1.2410.98
300_A303_E1.2350.98
182_V186_T1.2310.98
130_H396_I1.2290.98
240_V243_L1.2290.98
570_A574_L1.2260.98
282_L286_L1.2250.98
754_L805_A1.2240.98
303_E306_R1.2230.98
830_D839_G1.2230.98
595_E618_T1.2220.98
840_R843_Q1.2200.98
563_E756_F1.2180.98
627_D630_T1.2180.98
697_A706_A1.2130.97
974_R977_L1.2090.97
1105_H1108_D1.2070.97
262_Q265_W1.2060.97
540_L545_D1.2050.97
383_I397_F1.2050.97
497_P505_E1.2040.97
542_N545_D1.2040.97
974_R978_E1.2030.97
556_V571_L1.2010.97
500_K505_E1.2010.97
502_W505_E1.2000.97
282_L289_F1.1970.97
632_N635_E1.1950.97
841_L845_G1.1940.97
561_R740_T1.1930.97
244_D270_S1.1930.97
302_G317_L1.1930.97
286_L289_F1.1910.97
843_Q847_P1.1910.97
1064_G1113_L1.1850.97
558_V564_A1.1850.97
599_L664_L1.1850.97
453_M457_V1.1840.97
343_K350_G1.1830.97
12_R39_R1.1810.97
951_P955_L1.1790.97
1027_I1116_L1.1740.97
298_T302_G1.1660.97
839_G844_K1.1640.97
671_A675_L1.1630.97
62_V383_I1.1620.97
802_L806_L1.1620.97
1076_Y1122_L1.1610.97
313_I323_I1.1610.97
130_H350_G1.1600.97
830_D840_R1.1590.97
567_V738_I1.1580.97
295_E313_I1.1560.97
837_A844_K1.1560.97
254_R259_R1.1550.97
291_Q294_L1.1530.97
291_Q299_K1.1530.97
310_F313_I1.1520.97
236_W240_V1.1510.97
838_L844_K1.1500.97
750_P810_V1.1490.96
253_D256_K1.1480.96
133_C396_I1.1460.96
859_A863_D1.1460.96
133_C800_R1.1450.96
60_L381_A1.1420.96
204_E207_V1.1400.96
558_V567_V1.1390.96
13_L17_G1.1380.96
1084_N1107_Y1.1380.96
80_I118_E1.1370.96
520_Q573_L1.1360.96
644_E648_Y1.1330.96
38_L79_N1.1330.96
182_V187_W1.1330.96
1119_H1125_R1.1320.96
307_H311_E1.1320.96
1074_G1127_A1.1310.96
603_V648_Y1.1310.96
291_Q296_D1.1290.96
257_F262_Q1.1290.96
730_E735_L1.1270.96
1000_A1003_N1.1270.96
61_V80_I1.1230.96
307_H313_I1.1230.96
264_K267_D1.1210.96
568_R738_I1.1190.96
140_N374_I1.1170.96
386_F433_A1.1140.96
861_C864_D1.1140.96
680_G683_R1.1130.96
836_S842_L1.1130.96
293_F298_T1.1110.96
294_L298_T1.1090.96
1025_L1062_L1.1090.96
963_D1019_V1.1070.96
52_R58_E1.1060.96
265_W269_I1.1010.96
963_D966_Q1.1010.96
297_R306_R1.1010.96
835_Q843_Q1.0980.95
292_R298_T1.0960.95
1102_M1105_H1.0950.95
903_V906_Y1.0940.95
596_M690_I1.0920.95
327_V330_R1.0900.95
254_R262_Q1.0880.95
759_N762_V1.0850.95
729_L735_L1.0840.95
285_S289_F1.0820.95
925_D928_A1.0810.95
254_R257_F1.0800.95
340_A344_R1.0790.95
205_A336_R1.0780.95
542_N546_A1.0780.95
313_I321_L1.0760.95
152_L354_M1.0760.95
23_A26_G1.0760.95
788_D791_E1.0760.95
296_D299_K1.0750.95
57_E123_E1.0750.95
446_N449_S1.0750.95
621_M644_E1.0730.95
834_H840_R1.0730.95
832_D840_R1.0730.95
955_L959_F1.0700.95
674_L687_I1.0690.95
364_S367_G1.0690.95
860_L863_D1.0680.95
499_M504_M1.0680.95
769_H793_E1.0670.95
255_R265_W1.0660.95
170_R334_E1.0660.95
63_T68_A1.0660.95
973_V977_L1.0650.95
597_L601_Q1.0650.95
552_S734_H1.0620.95
656_G659_P1.0620.95
657_V661_L1.0610.95
137_L144_S1.0590.94
162_Q342_E1.0590.94
1010_S1014_A1.0570.94
859_A862_D1.0560.94
379_P402_H1.0550.94
840_R845_G1.0540.94
26_G29_K1.0540.94
163_A167_F1.0530.94
200_Y332_L1.0530.94
603_V660_M1.0520.94
992_E996_A1.0520.94
182_V193_L1.0500.94
165_A194_L1.0490.94
58_E377_R1.0470.94
1071_R1074_G1.0440.94
260_S264_K1.0430.94
892_T906_Y1.0430.94
297_R313_I1.0430.94
25_A30_T1.0410.94
43_G53_P1.0410.94
842_L846_E1.0410.94
78_S82_E1.0400.94
958_L990_L1.0400.94
137_L361_A1.0400.94
380_V408_A1.0390.94
292_R297_R1.0370.94
164_C335_I1.0340.94
671_A688_L1.0330.94
1090_S1101_A1.0330.94
1072_H1128_D1.0310.94
306_R316_L1.0310.94
58_E376_T1.0310.94
232_V235_Q1.0290.94
492_K502_W1.0280.94
835_Q844_K1.0280.94
302_G316_L1.0270.93
295_E299_K1.0260.93
477_P480_S1.0220.93
390_D429_T1.0220.93
23_A30_T1.0210.93
753_W812_H1.0200.93
228_R232_V1.0190.93
901_W905_S1.0150.93
243_L246_L1.0150.93
992_E995_T1.0140.93
305_P310_F1.0130.93
31_F447_W1.0110.93
312_A317_L1.0110.93
579_V735_L1.0100.93
581_L743_K1.0100.93
569_D573_L1.0080.93
177_R181_Q1.0080.93
686_D726_Q1.0080.93
39_R43_G1.0070.93
840_R846_E1.0070.93
319_E322_S1.0070.93
670_I674_L1.0050.93
587_V689_H1.0030.93
1026_P1059_R1.0020.93
1077_Y1128_D1.0010.93
605_T608_R0.9980.93
221_R225_I0.9970.92
295_E306_R0.9950.92
242_E245_A0.9940.92
838_L845_G0.9940.92
433_A437_V0.9930.92
66_E154_E0.9930.92
265_W268_K0.9920.92
973_V987_E0.9890.92
26_G30_T0.9880.92
267_D270_S0.9870.92
1075_R1125_R0.9830.92
1021_M1069_V0.9820.92
838_L843_Q0.9820.92
835_Q842_L0.9800.92
222_H225_I0.9790.92
540_L546_A0.9790.92
1000_A1004_E0.9790.92
905_S909_L0.9780.92
21_I32_T0.9780.92
737_Q749_Y0.9740.92
984_S987_E0.9730.92
831_T836_S0.9730.92
526_I551_A0.9730.92
926_V929_A0.9700.91
25_A29_K0.9690.91
318_A321_L0.9690.91
658_M691_S0.9680.91
339_V350_G0.9670.91
27_T390_D0.9670.91
238_D241_G0.9660.91
296_D300_A0.9620.91
930_G938_P0.9600.91
833_V841_L0.9600.91
806_L813_C0.9600.91
303_E313_I0.9590.91
775_E786_S0.9590.91
336_R340_A0.9580.91
25_A28_G0.9580.91
898_G901_W0.9580.91
836_S841_L0.9570.91
312_A315_Q0.9560.91
790_A794_R0.9550.91
260_S266_I0.9540.91
689_H693_L0.9540.91
297_R302_G0.9530.91
334_E338_T0.9500.91
1123_R1127_A0.9500.91
61_V386_F0.9500.91
459_K463_Q0.9500.91
135_R139_L0.9490.90
920_L923_R0.9490.90
902_R905_S0.9460.90
427_I430_Y0.9460.90
221_R227_A0.9460.90
299_K310_F0.9460.90
133_C449_S0.9440.90
976_K981_G0.9440.90
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306_R323_I0.6070.61
661_L691_S0.6070.61
727_M733_K0.6070.61
797_E800_R0.6070.61
126_V700_Q0.6050.61
421_A794_R0.6040.60
951_P954_F0.6030.60
298_T304_T0.6030.60
416_K461_F0.6030.60
306_R312_A0.6020.60
235_Q239_A0.6020.60
235_Q238_D0.6020.60
998_L1001_P0.6010.60
24_S748_E0.6010.60
451_P483_K0.6010.60
429_T433_A0.6010.60
831_T839_G0.6010.60
473_I476_I0.6010.60
832_D843_Q0.6010.60
262_Q276_E0.6000.60
291_Q300_A0.6000.60
308_P319_E0.5990.60
133_C354_M0.5990.60
512_G516_S0.5980.60
167_F330_R0.5980.60
377_R1120_R0.5980.60
250_S259_R0.5980.60
498_A502_W0.5980.60
588_F710_W0.5980.60
269_I275_E0.5980.60
21_I36_L0.5980.60
300_A305_P0.5980.60
650_Q873_G0.5980.60
933_S938_P0.5980.60
892_T898_G0.5970.60
291_Q318_A0.5970.60
769_H774_F0.5960.59
169_R173_Y0.5960.59
558_V563_E0.5960.59
425_A617_A0.5960.59
587_V693_L0.5950.59
450_A748_E0.5950.59
73_R456_S0.5950.59
410_L425_A0.5950.59
894_Q897_P0.5950.59
158_L520_Q0.5940.59
478_V482_G0.5940.59
984_S1074_G0.5930.59
292_R301_G0.5930.59
281_Q287_E0.5920.59
283_P291_Q0.5920.59
40_L72_L0.5920.59
424_G755_P0.5900.59
159_L342_E0.5900.59
394_Y411_L0.5900.59
55_T113_W0.5900.59
60_L127_F0.5900.59
767_F770_D0.5890.59
378_F381_A0.5890.59
915_G919_D0.5890.59
665_M671_A0.5880.58
1020_E1080_D0.5870.58
69_T127_F0.5870.58
401_W409_L0.5860.58
211_P333_A0.5860.58
882_D1101_A0.5860.58
526_I556_V0.5850.58
685_T689_H0.5850.58
906_Y909_L0.5850.58
227_A231_T0.5850.58
272_W275_E0.5840.58
491_F499_M0.5830.58
529_W554_I0.5830.58
305_P317_L0.5820.58
559_R743_K0.5810.58
587_V1065_F0.5810.58
492_K495_T0.5800.57
79_N83_L0.5800.57
124_A422_F0.5790.57
1080_D1114_Y0.5790.57
495_T500_K0.5790.57
392_Q740_T0.5790.57
257_F276_E0.5780.57
901_W907_S0.5780.57
304_T318_A0.5780.57
355_L359_D0.5770.57
541_M544_D0.5770.57
291_Q301_G0.5770.57
802_L815_L0.5770.57
60_L72_L0.5770.57
38_L117_A0.5770.57
76_I665_M0.5770.57
869_T872_T0.5760.57
123_E381_A0.5760.57
67_A739_V0.5760.57
968_V999_Q0.5760.57
796_A799_L0.5760.57
358_L421_A0.5740.57
410_L618_T0.5730.56
285_S290_S0.5730.56
859_A864_D0.5720.56
382_M587_V0.5720.56
1075_R1128_D0.5720.56
84_R111_A0.5720.56
437_V440_H0.5690.56
38_L76_I0.5690.56
24_S416_K0.5690.56
238_D242_E0.5690.56
23_A65_T0.5690.56
43_G52_R0.5680.56
959_F1081_Y0.5680.56
295_E301_G0.5680.56
126_V950_S0.5680.56
383_I800_R0.5680.56
475_F481_A0.5680.56
183_V186_T0.5680.56
418_A561_R0.5670.56
302_G309_L0.5670.56
355_L427_I0.5670.56
30_T68_A0.5670.56
383_I568_R0.5670.56
18_E418_A0.5670.56
841_L846_E0.5670.56
991_T995_T0.5660.56
162_Q346_R0.5660.56
37_Y69_T0.5650.55
1122_L1125_R0.5650.55
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791_E794_R0.5640.55
299_K313_I0.5640.55
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644_E647_G0.5630.55
397_F738_I0.5630.55
567_V755_P0.5620.55
178_E181_Q0.5620.55
262_Q272_W0.5610.55
125_A382_M0.5610.55
84_R118_E0.5610.55
593_A707_L0.5600.55
952_G1082_K0.5600.55
590_T753_W0.5600.55
830_D842_L0.5600.55
168_W173_Y0.5600.55
299_K306_R0.5600.55
1112_Q1115_T0.5600.55
817_V1062_L0.5600.55
255_R267_D0.5590.55
948_G1086_L0.5590.55
806_L815_L0.5580.55
307_H316_L0.5580.55
590_T1069_V0.5580.55
108_A112_Q0.5570.54
256_K262_Q0.5570.54
24_S114_L0.5570.54
121_M1019_V0.5570.54
955_L990_L0.5570.54
596_M918_Q0.5560.54
907_S919_D0.5560.54
300_A310_F0.5560.54
25_A416_K0.5560.54
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162_Q1089_D0.5530.54
349_L358_L0.5530.54
314_D321_L0.5530.54
117_A355_L0.5530.54
1010_S1077_Y0.5520.54
298_T301_G0.5520.54
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838_L846_E0.5520.54
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606_P610_N0.5510.54
798_D801_L0.5510.54
226_V230_D0.5510.54
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162_Q167_F0.5500.53
389_T426_D0.5500.53
892_T903_V0.5500.53
163_A329_T0.5500.53
877_P880_V0.5490.53
254_R261_N0.5490.53
596_M600_L0.5490.53
563_E567_V0.5480.53
260_S276_E0.5480.53
258_N264_K0.5470.53
31_F748_E0.5470.53
369_V373_A0.5470.53
931_V934_V0.5470.53
309_L314_D0.5470.53
296_D302_G0.5460.53
902_R910_Q0.5460.53
27_T433_A0.5450.53
994_I998_L0.5450.53
133_C797_E0.5450.53
25_A65_T0.5450.53
295_E311_E0.5450.53
1101_A1104_A0.5450.53
1014_A1017_K0.5440.53
462_S477_P0.5440.53
579_V582_S0.5440.53
446_N749_Y0.5430.53
24_S134_Q0.5430.53
926_V931_V0.5430.53
794_R798_D0.5430.53
930_G933_S0.5420.52
317_L323_I0.5420.52
394_Y427_I0.5410.52
420_Y461_F0.5410.52
20_L32_T0.5410.52
921_M926_V0.5410.52
837_A848_Q0.5410.52
994_I1003_N0.5400.52
308_P317_L0.5400.52
792_A796_A0.5400.52
690_I693_L0.5400.52
616_L623_L0.5400.52
597_L708_V0.5400.52
127_F139_L0.5400.52
518_M558_V0.5390.52
988_P992_E0.5390.52
265_W288_K0.5390.52
155_D744_S0.5390.52
907_S979_L0.5390.52
952_G1114_Y0.5380.52
445_T479_K0.5380.52
27_T36_L0.5380.52
225_I242_E0.5370.52
915_G922_P0.5360.52
454_V483_K0.5360.52
360_S1073_E0.5360.52
556_V736_V0.5360.52
1080_D1110_Q0.5350.52
31_F79_N0.5350.52
875_N920_L0.5350.52
446_N741_I0.5350.52
700_Q734_H0.5350.52
909_L913_G0.5340.51
789_L793_E0.5340.51
897_P900_N0.5340.51
37_Y41_L0.5340.51
285_S288_K0.5340.51
476_I480_S0.5330.51
224_Q227_A0.5330.51
62_V443_L0.5320.51
198_N202_Q0.5320.51
304_T309_L0.5320.51
555_S739_V0.5310.51
596_M994_I0.5310.51
67_A117_A0.5310.51
493_G502_W0.5300.51
998_L1083_S0.5300.51
946_P950_S0.5300.51
977_L981_G0.5300.51
353_D814_S0.5300.51
309_L316_L0.5290.51
800_R1064_G0.5280.51
1067_D1082_K0.5280.51
295_E321_L0.5280.51
27_T1116_L0.5280.51
386_F434_R0.5280.51
977_L982_F0.5280.51
130_H391_P0.5280.51
32_T381_A0.5270.50
120_Q123_E0.5270.50
23_A63_T0.5270.50
154_E351_F0.5270.50
171_H175_L0.5270.50
600_L604_M0.5270.50
561_R564_A0.5260.50
295_E300_A0.5260.50
398_R403_H0.5250.50
935_V942_P0.5250.50
303_E317_L0.5250.50
956_H1082_K0.5250.50
251_G255_R0.5240.50
263_A266_I0.5240.50
244_D247_I0.5240.50
832_D839_G0.5240.50
339_V1111_Y0.5230.50
350_G354_M0.5220.50
686_D693_L0.5220.50
842_L845_G0.5220.50
232_V242_E0.5220.50
1076_Y1124_H0.5220.50
415_P429_T0.5220.50
133_C355_L0.5210.50
450_A453_M0.5210.50
1082_K1110_Q0.5210.50
956_H1080_D0.5210.50
32_T343_K0.5200.50
141_A389_T0.5200.50
929_A932_A0.5200.50
31_F744_S0.5200.50
206_P598_W0.5200.50
200_Y447_W0.5200.50
551_A554_I0.5200.50
303_E308_P0.5190.49
310_F321_L0.5190.49
252_I286_L0.5190.49
447_W481_A0.5190.49
26_G65_T0.5190.49
705_H708_V0.5190.49
290_S294_L0.5180.49
431_M473_I0.5180.49
928_A935_V0.5180.49
596_M693_L0.5180.49
339_V657_V0.5180.49
256_K297_R0.5180.49
167_F171_H0.5180.49
358_L473_I0.5180.49
282_L285_S0.5170.49
253_D265_W0.5170.49
321_L325_D0.5170.49
226_V984_S0.5170.49
38_L83_L0.5160.49
839_G845_G0.5160.49
75_R389_T0.5150.49
447_W800_R0.5150.49
62_V141_A0.5150.49
553_D751_L0.5140.49
398_R401_W0.5140.49
217_T221_R0.5140.49
496_Q500_K0.5130.49
32_T427_I0.5130.49
286_L313_I0.5130.49
27_T37_Y0.5130.49
519_A800_R0.5120.48
21_I623_L0.5120.48
390_D730_E0.5120.48
1126_I1131_Y0.5120.48
24_S564_A0.5110.48
394_Y416_K0.5110.48
138_N700_Q0.5110.48
233_K243_L0.5110.48
30_T75_R0.5110.48
1123_R1126_I0.5100.48
164_C167_F0.5100.48
73_R688_L0.5100.48
65_T71_E0.5100.48
36_L380_V0.5100.48
310_F316_L0.5090.48
382_M679_G0.5090.48
587_V1023_F0.5090.48
277_T281_Q0.5090.48
316_L321_L0.5090.48
137_L368_E0.5090.48
32_T141_A0.5080.48
230_D234_Q0.5080.48
157_S706_A0.5080.48
56_V124_A0.5080.48
501_M639_D0.5080.48
26_G63_T0.5080.48
989_V993_W0.5070.48
163_A418_A0.5070.48
24_S433_A0.5070.48
37_Y67_A0.5070.48
241_G271_A0.5070.48
836_S864_D0.5060.48
361_A374_I0.5060.48
647_G663_A0.5050.48
978_E994_I0.5050.48
492_K528_D0.5050.48
210_A356_S0.5050.48
477_P482_G0.5050.48
727_M730_E0.5050.48
129_I383_I0.5040.47
694_L697_A0.5040.47
219_A296_D0.5040.47
612_L645_F0.5040.47
252_I265_W0.5030.47
21_I335_I0.5030.47
389_T400_I0.5030.47
120_Q418_A0.5030.47
832_D842_L0.5020.47
302_G323_I0.5020.47
269_I272_W0.5020.47
891_K895_R0.5020.47
41_L154_E0.5020.47
960_E1130_D0.5020.47
832_D841_L0.5020.47
378_F396_I0.5020.47
262_Q268_K0.5010.47
956_H1114_Y0.5010.47
322_S325_D0.5010.47
640_V759_N0.5010.47
776_A781_N0.5010.47
203_G768_Y0.5000.47
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3u4qA 1 0.8508 100 0.316 Contact Map
1pjrA 1 0.4992 100 0.552 Contact Map
4c2tA 1 0.5195 100 0.554 Contact Map
1uaaA 2 0.5085 100 0.57 Contact Map
3lfuA 1 0.5059 100 0.58 Contact Map
4c2uA 1 0.5229 100 0.583 Contact Map
3u4qB 1 0.7627 100 0.606 Contact Map
4pj3A 1 0.4678 100 0.744 Contact Map
2xzlA 1 0.3653 100 0.787 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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