RECB - ECOLI - GREMLIN Contacts

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RECB - RecBCD enzyme subunit RecB

UniProt:	P08394	Sequences: MSDVAETLDPLRLPLQGERLIEASAGTGKTFTIAALYLRLLLGLGGSAAFPRPLTVEELLVVTFTEAATAELRGRIRSNIHELRIACLRETTDNPLYERLLEEIDDKAQAAQWLLLAERQMDEAAVFTIHGFCQRMLNLNAFESGMLFEQQLIEDESLLRYQACADFWRRHCYPLPREIAQVVFETWKGPQALLRDINRYLQGEAPVIKAPPPDDETLASRHAQIVARIDTVKQQWRDAVGELDALIESSGIDRRKFNRSNQAKWIDKISAWAEEETNSYQLPESLEKFSQRFLEDRTKAGGETPRHPLFEAIDQLLAEPLSIRDLVITRALAEIRETVAREKRRRGELGFDDMLSRLDSALRSESGEVLAAAIRTRFPVAMIDEFQDTDPQQYRIFRRIWHHQPETALLLIGDPKQAIYAFRGADIFTYMKARSEVHAHYTLDTNWRSAPGMVNSVNKLFSQTDDAFMFREIPFIPVKSAGKNQALRFVFKGETQPAMKMWLMEGESCGVGDYQSTMAQVCAAQIRDWLQAGQRGEALLMNGDDARPVRASDISVLVRSRQEAAQVRDALTLLEIPSVYLSNRDSVFETLEAQEMLWLLQAVMTPERENTLRSALATSMMGLNALDIETLNNDEHAWDVVVEEFDGYRQIWRKRGVMPMLRALMSARNIAENLLATAGGERRLTDILHISELLQEAGTQLESEHALVRWLSQHILEPDSNASSQQMRLESDKHLVQIVTIHKSKGLEYPLVWLPFITNFRVQEQAFYHDRHSFEAVLDLNAAPESVDLAEAERLAEDLRLLYVALTRSVWHCSLGVAPLVRRRGDKKGDTDVHQSALGRLLQKGEPQDAAGLRTCIEALCDDDIAWQTAQTGDNQPWQVNDVSTAELNAKTLQRLPGDNWRVTSYSGLQQRGHGIAQDLMPRLDVDAAGVASVVEEPTLTPHQFPRGASPGTFLHSLFEDLDFTQPVDPNWVREKLELGGFESQWEPVLTEWITAVLQAPLNETGVSLSQLSARNKQVEMEFYLPISEPLIASQLDTLIRQFDPLSAGCPPLEFMQVRGMLKGFIDLVFRHEGRYYLLDYKSNWLGEDSSAYTQQAMAAAMQAHRYDLQYQLYTLALHRYLRHRIADYDYEHHFGGVIYLFLRGVDKEHPQQGIYTTRPNAGLIALMDEMFAGMTLEEA	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10824
Length:	1180 (1017)
Sequences:	3037 (2659)
Seq/√Len:	83.4

ECOLI - RECB
BACSU - ADDA

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
576_I	736_V	6.872	1.00
549_V	751_L	5.461	1.00
58_E	379_P	5.288	1.00
955_L	1083_S	4.985	1.00
748_E	810_V	4.929	1.00
170_R	338_T	4.831	1.00
739_V	749_Y	4.643	1.00
592_E	686_D	4.371	1.00
757_I	815_L	4.107	1.00
550_R	734_H	4.030	1.00
525_Q	528_D	4.028	1.00
601_Q	712_S	3.929	1.00
342_E	345_R	3.824	1.00
760_F	764_E	3.803	1.00
761_R	764_E	3.725	1.00
527_R	531_Q	3.668	1.00
130_H	354_M	3.556	1.00
71_E	75_R	3.536	1.00
523_A	574_L	3.294	1.00
526_I	554_I	3.264	1.00
500_K	503_L	3.145	1.00
499_M	502_W	3.134	1.00
553_D	750_P	3.123	1.00
451_P	455_N	3.119	1.00
754_L	815_L	3.107	1.00
55_T	58_E	3.053	1.00
313_I	317_L	3.043	1.00
525_Q	753_W	3.016	1.00
540_L	543_G	3.004	1.00
497_P	502_W	2.978	1.00
530_L	551_A	2.967	1.00
624_N	627_D	2.960	1.00
525_Q	814_S	2.950	1.00
343_K	353_D	2.949	1.00
522_C	755_P	2.909	1.00
136_M	358_L	2.907	1.00
1071_R	1124_H	2.832	1.00
1016_N	1071_R	2.825	1.00
359_D	395_R	2.814	1.00
830_D	833_V	2.773	1.00
559_R	798_D	2.762	1.00
760_F	763_Q	2.760	1.00
125_A	378_F	2.754	1.00
836_S	839_G	2.722	1.00
163_A	342_E	2.712	1.00
460_L	806_L	2.710	1.00
836_S	840_R	2.698	1.00
833_V	836_S	2.685	1.00
83_L	86_A	2.666	1.00
753_W	814_S	2.608	1.00
571_L	578_S	2.602	1.00
1070_F	1079_L	2.571	1.00
528_D	532_A	2.569	1.00
647_G	667_A	2.559	1.00
524_A	574_L	2.525	1.00
608_R	611_T	2.512	1.00
421_A	790_A	2.482	1.00
627_D	637_A	2.472	1.00
136_M	374_I	2.460	1.00
130_H	352_D	2.421	1.00
520_Q	574_L	2.418	1.00
1071_R	1076_Y	2.411	1.00
648_Y	667_A	2.401	1.00
374_I	378_F	2.397	1.00
834_H	838_L	2.370	1.00
66_E	130_H	2.358	1.00
832_D	836_S	2.355	1.00
592_E	683_R	2.353	1.00
302_G	313_I	2.334	1.00
349_L	354_M	2.305	1.00
558_V	738_I	2.294	1.00
342_E	346_R	2.289	1.00
130_H	355_L	2.286	1.00
838_L	842_L	2.257	1.00
34_A	76_I	2.254	1.00
830_D	834_H	2.239	1.00
599_L	615_A	2.236	1.00
381_A	400_I	2.215	1.00
559_R	801_L	2.214	1.00
983_E	986_W	2.212	1.00
130_H	137_L	2.190	1.00
564_A	738_I	2.187	1.00
338_T	341_R	2.179	1.00
215_D	333_A	2.175	1.00
303_E	307_H	2.175	1.00
1068_L	1079_L	2.157	1.00
144_S	361_A	2.152	1.00
596_M	687_I	2.147	1.00
972_W	975_E	2.136	1.00
435_S	467_A	2.113	1.00
519_A	523_A	2.109	1.00
830_D	836_S	2.105	1.00
527_R	574_L	2.096	1.00
291_Q	313_I	2.073	1.00
837_A	840_R	2.069	1.00
957_S	961_D	2.069	1.00
79_N	82_E	2.061	1.00
540_L	547_R	2.046	1.00
14_P	40_L	2.032	1.00
833_V	837_A	2.028	1.00
492_K	497_P	2.025	1.00
834_H	842_L	2.021	1.00
291_Q	295_E	2.017	1.00
837_A	841_L	2.016	1.00
830_D	835_Q	2.009	1.00
837_A	842_L	1.998	1.00
130_H	390_D	1.996	1.00
839_G	843_Q	1.994	1.00
555_S	749_Y	1.988	1.00
839_G	842_L	1.983	1.00
314_D	317_L	1.973	1.00
302_G	306_R	1.969	1.00
255_R	258_N	1.965	1.00
314_D	318_A	1.955	1.00
520_Q	570_A	1.945	1.00
949_A	953_T	1.944	1.00
834_H	841_L	1.943	1.00
833_V	840_R	1.939	1.00
1103_Q	1132_E	1.936	1.00
831_T	834_H	1.934	1.00
836_S	844_K	1.930	1.00
741_I	805_A	1.914	1.00
832_D	835_Q	1.905	1.00
310_F	317_L	1.900	1.00
832_D	837_A	1.898	1.00
833_V	839_G	1.884	1.00
17_G	439_A	1.884	1.00
22_E	415_P	1.877	1.00
970_P	974_R	1.872	1.00
1078_L	1118_L	1.860	1.00
1072_H	1127_A	1.839	1.00
363_R	395_R	1.838	1.00
938_P	942_P	1.828	1.00
551_A	577_P	1.827	1.00
651_I	663_A	1.823	1.00
258_N	262_Q	1.822	1.00
306_R	310_F	1.818	1.00
547_R	553_D	1.809	1.00
665_M	687_I	1.806	1.00
309_L	313_I	1.804	1.00
835_Q	839_G	1.799	1.00
526_I	753_W	1.798	1.00
151_Q	157_S	1.796	1.00
675_L	684_L	1.790	1.00
651_I	655_R	1.789	1.00
1001_P	1004_E	1.785	1.00
549_V	554_I	1.780	1.00
338_T	342_E	1.778	1.00
313_I	318_A	1.768	1.00
456_S	806_L	1.755	1.00
1069_V	1118_L	1.753	1.00
381_A	401_W	1.751	1.00
496_Q	502_W	1.748	1.00
984_S	988_P	1.746	1.00
529_W	753_W	1.741	1.00
754_L	757_I	1.731	1.00
694_L	707_L	1.722	1.00
499_M	503_L	1.714	1.00
153_I	348_E	1.714	1.00
522_C	753_W	1.714	1.00
529_W	814_S	1.704	1.00
37_Y	76_I	1.695	1.00
125_A	135_R	1.694	1.00
313_I	316_L	1.687	1.00
834_H	837_A	1.687	1.00
37_Y	61_V	1.687	1.00
298_T	313_I	1.681	1.00
292_R	295_E	1.675	1.00
171_H	334_E	1.674	1.00
254_R	258_N	1.668	1.00
525_Q	529_W	1.661	1.00
292_R	296_D	1.654	1.00
1066_I	1069_V	1.651	1.00
901_W	904_T	1.650	1.00
31_F	35_A	1.644	1.00
833_V	844_K	1.644	1.00
159_L	163_A	1.640	1.00
74_G	78_S	1.626	1.00
418_A	425_A	1.622	1.00
293_F	296_D	1.619	1.00
421_A	793_E	1.616	1.00
835_Q	838_L	1.613	1.00
108_A	111_A	1.611	1.00
496_Q	499_M	1.587	1.00
497_P	501_M	1.578	1.00
499_M	505_E	1.578	1.00
918_Q	921_M	1.570	1.00
833_V	838_L	1.569	1.00
252_I	255_R	1.566	1.00
1075_R	1127_A	1.565	1.00
312_A	316_L	1.561	1.00
497_P	503_L	1.556	1.00
836_S	843_Q	1.552	1.00
444_D	479_K	1.544	1.00
602_A	615_A	1.540	1.00
363_R	399_R	1.536	1.00
258_N	265_W	1.536	1.00
372_A	375_R	1.535	1.00
80_I	114_L	1.534	1.00
143_E	370_L	1.534	1.00
858_E	863_D	1.532	1.00
140_N	373_A	1.531	1.00
529_W	549_V	1.527	1.00
1115_T	1119_H	1.523	0.99
40_L	380_V	1.523	0.99
1025_L	1117_A	1.522	0.99
497_P	500_K	1.510	0.99
540_L	544_D	1.505	0.99
134_Q	138_N	1.504	0.99
570_A	573_L	1.503	0.99
840_R	844_K	1.502	0.99
450_A	811_W	1.499	0.99
62_V	129_I	1.499	0.99
160_R	202_Q	1.498	0.99
858_E	861_C	1.497	0.99
261_N	264_K	1.496	0.99
261_N	265_W	1.494	0.99
492_K	499_M	1.494	0.99
498_A	503_L	1.488	0.99
244_D	248_E	1.481	0.99
598_W	614_S	1.476	0.99
254_R	265_W	1.472	0.99
341_R	345_R	1.467	0.99
321_L	324_R	1.462	0.99
476_I	479_K	1.458	0.99
833_V	842_L	1.458	0.99
137_L	358_L	1.457	0.99
1108_D	1112_Q	1.448	0.99
838_L	841_L	1.446	0.99
221_R	228_R	1.444	0.99
1116_L	1120_R	1.443	0.99
229_I	233_K	1.440	0.99
830_D	837_A	1.439	0.99
751_L	814_S	1.438	0.99
518_M	816_G	1.416	0.99
306_R	313_I	1.409	0.99
295_E	298_T	1.408	0.99
533_G	548_P	1.403	0.99
669_N	672_E	1.402	0.99
308_P	312_A	1.401	0.99
140_N	143_E	1.396	0.99
41_L	80_I	1.395	0.99
62_V	397_F	1.391	0.99
1072_H	1075_R	1.387	0.99
137_L	354_M	1.386	0.99
77_R	121_M	1.384	0.99
1010_S	1072_H	1.381	0.99
835_Q	840_R	1.374	0.99
663_A	667_A	1.371	0.99
340_A	357_R	1.369	0.99
166_D	342_E	1.365	0.99
166_D	338_T	1.361	0.99
291_Q	298_T	1.359	0.99
296_D	313_I	1.359	0.99
975_E	979_L	1.359	0.99
834_H	845_G	1.358	0.99
432_K	436_E	1.357	0.99
571_L	738_I	1.357	0.99
1070_F	1077_Y	1.353	0.99
600_L	661_L	1.353	0.99
959_F	994_I	1.348	0.99
258_N	261_N	1.348	0.99
158_L	339_V	1.345	0.99
66_E	134_Q	1.340	0.99
172_C	190_P	1.340	0.99
617_A	625_A	1.339	0.99
233_K	236_W	1.333	0.99
150_Q	349_L	1.332	0.99
770_D	773_S	1.326	0.99
858_E	864_D	1.326	0.99
265_W	272_W	1.323	0.99
310_F	314_D	1.318	0.99
355_L	390_D	1.310	0.98
167_F	334_E	1.303	0.98
938_P	941_T	1.302	0.98
35_A	79_N	1.301	0.98
1028_S	1059_R	1.299	0.98
972_W	976_K	1.296	0.98
334_E	337_E	1.295	0.98
35_A	39_R	1.294	0.98
834_H	839_G	1.293	0.98
415_P	430_Y	1.290	0.98
355_L	392_Q	1.290	0.98
24_S	27_T	1.289	0.98
57_E	120_Q	1.289	0.98
462_S	480_S	1.287	0.98
255_R	262_Q	1.287	0.98
291_Q	317_L	1.278	0.98
307_H	310_F	1.278	0.98
18_E	437_V	1.273	0.98
558_V	755_P	1.271	0.98
191_Q	194_L	1.269	0.98
293_F	313_I	1.269	0.98
302_G	305_P	1.266	0.98
934_V	938_P	1.264	0.98
833_V	845_G	1.254	0.98
835_Q	841_L	1.252	0.98
303_E	310_F	1.252	0.98
252_I	258_N	1.251	0.98
37_Y	56_V	1.250	0.98
39_R	42_L	1.246	0.98
491_F	500_K	1.244	0.98
130_H	349_L	1.241	0.98
300_A	303_E	1.235	0.98
182_V	186_T	1.231	0.98
130_H	396_I	1.229	0.98
240_V	243_L	1.229	0.98
570_A	574_L	1.226	0.98
282_L	286_L	1.225	0.98
754_L	805_A	1.224	0.98
303_E	306_R	1.223	0.98
830_D	839_G	1.223	0.98
595_E	618_T	1.222	0.98
840_R	843_Q	1.220	0.98
563_E	756_F	1.218	0.98
627_D	630_T	1.218	0.98
697_A	706_A	1.213	0.97
974_R	977_L	1.209	0.97
1105_H	1108_D	1.207	0.97
262_Q	265_W	1.206	0.97
540_L	545_D	1.205	0.97
383_I	397_F	1.205	0.97
497_P	505_E	1.204	0.97
542_N	545_D	1.204	0.97
974_R	978_E	1.203	0.97
556_V	571_L	1.201	0.97
500_K	505_E	1.201	0.97
502_W	505_E	1.200	0.97
282_L	289_F	1.197	0.97
632_N	635_E	1.195	0.97
841_L	845_G	1.194	0.97
561_R	740_T	1.193	0.97
244_D	270_S	1.193	0.97
302_G	317_L	1.193	0.97
286_L	289_F	1.191	0.97
843_Q	847_P	1.191	0.97
1064_G	1113_L	1.185	0.97
558_V	564_A	1.185	0.97
599_L	664_L	1.185	0.97
453_M	457_V	1.184	0.97
343_K	350_G	1.183	0.97
12_R	39_R	1.181	0.97
951_P	955_L	1.179	0.97
1027_I	1116_L	1.174	0.97
298_T	302_G	1.166	0.97
839_G	844_K	1.164	0.97
671_A	675_L	1.163	0.97
62_V	383_I	1.162	0.97
802_L	806_L	1.162	0.97
1076_Y	1122_L	1.161	0.97
313_I	323_I	1.161	0.97
130_H	350_G	1.160	0.97
830_D	840_R	1.159	0.97
567_V	738_I	1.158	0.97
295_E	313_I	1.156	0.97
837_A	844_K	1.156	0.97
254_R	259_R	1.155	0.97
291_Q	294_L	1.153	0.97
291_Q	299_K	1.153	0.97
310_F	313_I	1.152	0.97
236_W	240_V	1.151	0.97
838_L	844_K	1.150	0.97
750_P	810_V	1.149	0.96
253_D	256_K	1.148	0.96
133_C	396_I	1.146	0.96
859_A	863_D	1.146	0.96
133_C	800_R	1.145	0.96
60_L	381_A	1.142	0.96
204_E	207_V	1.140	0.96
558_V	567_V	1.139	0.96
13_L	17_G	1.138	0.96
1084_N	1107_Y	1.138	0.96
80_I	118_E	1.137	0.96
520_Q	573_L	1.136	0.96
644_E	648_Y	1.133	0.96
38_L	79_N	1.133	0.96
182_V	187_W	1.133	0.96
1119_H	1125_R	1.132	0.96
307_H	311_E	1.132	0.96
1074_G	1127_A	1.131	0.96
603_V	648_Y	1.131	0.96
291_Q	296_D	1.129	0.96
257_F	262_Q	1.129	0.96
730_E	735_L	1.127	0.96
1000_A	1003_N	1.127	0.96
61_V	80_I	1.123	0.96
307_H	313_I	1.123	0.96
264_K	267_D	1.121	0.96
568_R	738_I	1.119	0.96
140_N	374_I	1.117	0.96
386_F	433_A	1.114	0.96
861_C	864_D	1.114	0.96
680_G	683_R	1.113	0.96
836_S	842_L	1.113	0.96
293_F	298_T	1.111	0.96
294_L	298_T	1.109	0.96
1025_L	1062_L	1.109	0.96
963_D	1019_V	1.107	0.96
52_R	58_E	1.106	0.96
265_W	269_I	1.101	0.96
963_D	966_Q	1.101	0.96
297_R	306_R	1.101	0.96
835_Q	843_Q	1.098	0.95
292_R	298_T	1.096	0.95
1102_M	1105_H	1.095	0.95
903_V	906_Y	1.094	0.95
596_M	690_I	1.092	0.95
327_V	330_R	1.090	0.95
254_R	262_Q	1.088	0.95
759_N	762_V	1.085	0.95
729_L	735_L	1.084	0.95
285_S	289_F	1.082	0.95
925_D	928_A	1.081	0.95
254_R	257_F	1.080	0.95
340_A	344_R	1.079	0.95
205_A	336_R	1.078	0.95
542_N	546_A	1.078	0.95
313_I	321_L	1.076	0.95
152_L	354_M	1.076	0.95
23_A	26_G	1.076	0.95
788_D	791_E	1.076	0.95
296_D	299_K	1.075	0.95
57_E	123_E	1.075	0.95
446_N	449_S	1.075	0.95
621_M	644_E	1.073	0.95
834_H	840_R	1.073	0.95
832_D	840_R	1.073	0.95
955_L	959_F	1.070	0.95
674_L	687_I	1.069	0.95
364_S	367_G	1.069	0.95
860_L	863_D	1.068	0.95
499_M	504_M	1.068	0.95
769_H	793_E	1.067	0.95
255_R	265_W	1.066	0.95
170_R	334_E	1.066	0.95
63_T	68_A	1.066	0.95
973_V	977_L	1.065	0.95
597_L	601_Q	1.065	0.95
552_S	734_H	1.062	0.95
656_G	659_P	1.062	0.95
657_V	661_L	1.061	0.95
137_L	144_S	1.059	0.94
162_Q	342_E	1.059	0.94
1010_S	1014_A	1.057	0.94
859_A	862_D	1.056	0.94
379_P	402_H	1.055	0.94
840_R	845_G	1.054	0.94
26_G	29_K	1.054	0.94
163_A	167_F	1.053	0.94
200_Y	332_L	1.053	0.94
603_V	660_M	1.052	0.94
992_E	996_A	1.052	0.94
182_V	193_L	1.050	0.94
165_A	194_L	1.049	0.94
58_E	377_R	1.047	0.94
1071_R	1074_G	1.044	0.94
260_S	264_K	1.043	0.94
892_T	906_Y	1.043	0.94
297_R	313_I	1.043	0.94
25_A	30_T	1.041	0.94
43_G	53_P	1.041	0.94
842_L	846_E	1.041	0.94
78_S	82_E	1.040	0.94
958_L	990_L	1.040	0.94
137_L	361_A	1.040	0.94
380_V	408_A	1.039	0.94
292_R	297_R	1.037	0.94
164_C	335_I	1.034	0.94
671_A	688_L	1.033	0.94
1090_S	1101_A	1.033	0.94
1072_H	1128_D	1.031	0.94
306_R	316_L	1.031	0.94
58_E	376_T	1.031	0.94
232_V	235_Q	1.029	0.94
492_K	502_W	1.028	0.94
835_Q	844_K	1.028	0.94
302_G	316_L	1.027	0.93
295_E	299_K	1.026	0.93
477_P	480_S	1.022	0.93
390_D	429_T	1.022	0.93
23_A	30_T	1.021	0.93
753_W	812_H	1.020	0.93
228_R	232_V	1.019	0.93
901_W	905_S	1.015	0.93
243_L	246_L	1.015	0.93
992_E	995_T	1.014	0.93
305_P	310_F	1.013	0.93
31_F	447_W	1.011	0.93
312_A	317_L	1.011	0.93
579_V	735_L	1.010	0.93
581_L	743_K	1.010	0.93
569_D	573_L	1.008	0.93
177_R	181_Q	1.008	0.93
686_D	726_Q	1.008	0.93
39_R	43_G	1.007	0.93
840_R	846_E	1.007	0.93
319_E	322_S	1.007	0.93
670_I	674_L	1.005	0.93
587_V	689_H	1.003	0.93
1026_P	1059_R	1.002	0.93
1077_Y	1128_D	1.001	0.93
605_T	608_R	0.998	0.93
221_R	225_I	0.997	0.92
295_E	306_R	0.995	0.92
242_E	245_A	0.994	0.92
838_L	845_G	0.994	0.92
433_A	437_V	0.993	0.92
66_E	154_E	0.993	0.92
265_W	268_K	0.992	0.92
973_V	987_E	0.989	0.92
26_G	30_T	0.988	0.92
267_D	270_S	0.987	0.92
1075_R	1125_R	0.983	0.92
1021_M	1069_V	0.982	0.92
838_L	843_Q	0.982	0.92
835_Q	842_L	0.980	0.92
222_H	225_I	0.979	0.92
540_L	546_A	0.979	0.92
1000_A	1004_E	0.979	0.92
905_S	909_L	0.978	0.92
21_I	32_T	0.978	0.92
737_Q	749_Y	0.974	0.92
984_S	987_E	0.973	0.92
831_T	836_S	0.973	0.92
526_I	551_A	0.973	0.92
926_V	929_A	0.970	0.91
25_A	29_K	0.969	0.91
318_A	321_L	0.969	0.91
658_M	691_S	0.968	0.91
339_V	350_G	0.967	0.91
27_T	390_D	0.967	0.91
238_D	241_G	0.966	0.91
296_D	300_A	0.962	0.91
930_G	938_P	0.960	0.91
833_V	841_L	0.960	0.91
806_L	813_C	0.960	0.91
303_E	313_I	0.959	0.91
775_E	786_S	0.959	0.91
336_R	340_A	0.958	0.91
25_A	28_G	0.958	0.91
898_G	901_W	0.958	0.91
836_S	841_L	0.957	0.91
312_A	315_Q	0.956	0.91
790_A	794_R	0.955	0.91
260_S	266_I	0.954	0.91
689_H	693_L	0.954	0.91
297_R	302_G	0.953	0.91
334_E	338_T	0.950	0.91
1123_R	1127_A	0.950	0.91
61_V	386_F	0.950	0.91
459_K	463_Q	0.950	0.91
135_R	139_L	0.949	0.90
920_L	923_R	0.949	0.90
902_R	905_S	0.946	0.90
427_I	430_Y	0.946	0.90
221_R	227_A	0.946	0.90
299_K	310_F	0.946	0.90
133_C	449_S	0.944	0.90
976_K	981_G	0.944	0.90
833_V	846_E	0.943	0.90
527_R	576_I	0.943	0.90
836_S	845_G	0.941	0.90
837_A	845_G	0.940	0.90
1110_Q	1114_Y	0.940	0.90
117_A	390_D	0.938	0.90
160_R	335_I	0.937	0.90
639_D	643_E	0.937	0.90
970_P	988_P	0.934	0.90
1119_H	1126_I	0.933	0.90
741_I	757_I	0.933	0.90
251_G	254_R	0.931	0.90
1064_G	1117_A	0.930	0.90
491_F	502_W	0.930	0.90
358_L	396_I	0.930	0.90
313_I	319_E	0.929	0.90
311_E	314_D	0.928	0.89
453_M	809_S	0.928	0.89
655_R	663_A	0.927	0.89
239_A	242_E	0.926	0.89
223_A	228_R	0.926	0.89
160_R	339_V	0.926	0.89
860_L	864_D	0.926	0.89
291_Q	302_G	0.925	0.89
313_I	322_S	0.924	0.89
769_H	773_S	0.924	0.89
20_L	67_A	0.922	0.89
626_L	630_T	0.920	0.89
500_K	525_Q	0.919	0.89
241_G	245_A	0.918	0.89
959_F	997_V	0.916	0.89
578_S	738_I	0.914	0.89
274_E	277_T	0.914	0.89
306_R	321_L	0.913	0.89
591_L	595_E	0.913	0.89
259_R	263_A	0.911	0.89
467_A	474_P	0.910	0.89
23_A	29_K	0.907	0.88
498_A	504_M	0.905	0.88
769_H	772_H	0.903	0.88
516_S	520_Q	0.902	0.88
1111_Y	1130_D	0.902	0.88
22_E	430_Y	0.902	0.88
596_M	661_L	0.902	0.88
262_Q	269_I	0.902	0.88
216_E	219_A	0.901	0.88
837_A	843_Q	0.900	0.88
995_T	999_Q	0.900	0.88
357_R	360_S	0.900	0.88
600_L	690_I	0.898	0.88
497_P	504_M	0.897	0.88
41_L	58_E	0.897	0.88
23_A	28_G	0.895	0.88
159_L	758_T	0.894	0.88
328_I	332_L	0.894	0.88
209_K	212_P	0.894	0.88
762_V	791_E	0.894	0.88
501_M	505_E	0.894	0.88
161_Y	194_L	0.893	0.88
616_L	621_M	0.892	0.88
254_R	263_A	0.891	0.87
130_H	389_T	0.888	0.87
602_A	645_F	0.884	0.87
32_T	36_L	0.884	0.87
40_L	382_M	0.882	0.87
893_L	906_Y	0.881	0.87
171_H	330_R	0.880	0.87
390_D	430_Y	0.880	0.87
223_A	227_A	0.879	0.87
160_R	198_N	0.879	0.87
299_K	302_G	0.879	0.87
835_Q	845_G	0.878	0.87
516_S	570_A	0.878	0.87
644_E	667_A	0.878	0.87
903_V	1063_K	0.878	0.87
266_I	269_I	0.878	0.87
313_I	320_P	0.875	0.87
224_Q	228_R	0.872	0.86
150_Q	354_M	0.871	0.86
895_R	899_D	0.870	0.86
964_F	1017_K	0.870	0.86
776_A	779_D	0.869	0.86
304_T	313_I	0.869	0.86
1023_F	1117_A	0.868	0.86
159_L	343_K	0.868	0.86
371_A	375_R	0.867	0.86
587_V	711_L	0.867	0.86
163_A	339_V	0.867	0.86
726_Q	731_S	0.866	0.86
843_Q	846_E	0.866	0.86
22_E	27_T	0.865	0.86
242_E	246_L	0.864	0.86
199_R	202_Q	0.864	0.86
638_W	642_V	0.864	0.86
844_K	847_P	0.864	0.86
418_A	617_A	0.863	0.86
284_E	287_E	0.862	0.86
830_D	843_Q	0.862	0.86
250_S	254_R	0.861	0.86
136_M	378_F	0.859	0.86
270_S	274_E	0.859	0.86
305_P	308_P	0.858	0.85
137_L	355_L	0.858	0.85
604_M	708_V	0.856	0.85
307_H	317_L	0.855	0.85
971_N	975_E	0.853	0.85
642_V	646_D	0.853	0.85
500_K	504_M	0.852	0.85
415_P	431_M	0.851	0.85
62_V	66_E	0.850	0.85
72_L	397_F	0.848	0.85
640_V	643_E	0.846	0.85
970_P	976_K	0.846	0.85
275_E	278_N	0.846	0.85
1011_Q	1014_A	0.844	0.85
298_T	306_R	0.844	0.85
480_S	483_K	0.843	0.84
36_L	410_L	0.842	0.84
19_R	441_Y	0.836	0.84
1017_K	1068_L	0.836	0.84
382_M	431_M	0.836	0.84
475_F	480_S	0.835	0.84
1072_H	1077_Y	0.835	0.84
1104_A	1108_D	0.835	0.84
21_I	441_Y	0.834	0.84
921_M	924_L	0.834	0.84
302_G	310_F	0.834	0.84
997_V	1000_A	0.834	0.84
292_R	317_L	0.834	0.84
1124_H	1127_A	0.833	0.84
259_R	265_W	0.832	0.84
32_T	430_Y	0.832	0.84
189_G	192_A	0.832	0.84
731_S	735_L	0.831	0.84
283_P	289_F	0.831	0.84
858_E	862_D	0.829	0.83
976_K	980_G	0.828	0.83
623_L	627_D	0.828	0.83
541_M	546_A	0.828	0.83
755_P	816_G	0.828	0.83
600_L	708_V	0.828	0.83
832_D	838_L	0.827	0.83
555_S	737_Q	0.826	0.83
723_S	726_Q	0.826	0.83
599_L	620_M	0.825	0.83
295_E	320_P	0.825	0.83
595_E	619_S	0.824	0.83
671_A	684_L	0.822	0.83
311_E	315_Q	0.822	0.83
395_R	398_R	0.821	0.83
271_A	275_E	0.820	0.83
931_V	935_V	0.819	0.83
306_R	318_A	0.818	0.83
416_K	803_Y	0.818	0.83
533_G	549_V	0.818	0.83
155_D	158_L	0.818	0.83
293_F	299_K	0.816	0.82
154_E	400_I	0.816	0.82
868_Q	871_Q	0.816	0.82
33_I	72_L	0.816	0.82
1022_E	1065_F	0.816	0.82
686_D	690_I	0.816	0.82
453_M	813_C	0.815	0.82
590_T	593_A	0.815	0.82
964_F	1019_V	0.814	0.82
832_D	844_K	0.814	0.82
240_V	247_I	0.814	0.82
192_A	195_R	0.813	0.82
971_N	974_R	0.813	0.82
902_R	906_Y	0.812	0.82
286_L	290_S	0.812	0.82
72_L	707_L	0.811	0.82
586_S	686_D	0.811	0.82
830_D	844_K	0.811	0.82
371_A	400_I	0.809	0.82
255_R	259_R	0.809	0.82
831_T	838_L	0.809	0.82
587_V	686_D	0.809	0.82
837_A	846_E	0.808	0.82
291_Q	297_R	0.808	0.82
42_L	83_L	0.808	0.82
830_D	838_L	0.808	0.82
970_P	973_V	0.807	0.82
499_M	506_G	0.807	0.82
54_L	58_E	0.807	0.82
252_I	257_F	0.806	0.82
291_Q	309_L	0.805	0.82
33_I	382_M	0.804	0.82
836_S	846_E	0.804	0.82
309_L	317_L	0.803	0.81
1023_F	1064_G	0.803	0.81
920_L	924_L	0.802	0.81
60_L	67_A	0.802	0.81
957_S	960_E	0.801	0.81
906_Y	911_Q	0.800	0.81
529_W	751_L	0.799	0.81
319_E	325_D	0.799	0.81
847_P	864_D	0.799	0.81
918_Q	922_P	0.799	0.81
841_L	844_K	0.799	0.81
901_W	909_L	0.798	0.81
297_R	300_A	0.798	0.81
259_R	262_Q	0.798	0.81
888_L	892_T	0.798	0.81
907_S	910_Q	0.798	0.81
259_R	272_W	0.798	0.81
621_M	641_V	0.796	0.81
831_T	835_Q	0.796	0.81
13_L	410_L	0.794	0.81
365_E	368_E	0.792	0.81
919_D	922_P	0.792	0.81
117_A	120_Q	0.791	0.80
397_F	409_L	0.790	0.80
751_L	812_H	0.789	0.80
237_R	240_V	0.789	0.80
833_V	843_Q	0.789	0.80
290_S	314_D	0.788	0.80
302_G	307_H	0.788	0.80
834_H	844_K	0.788	0.80
311_E	992_E	0.787	0.80
262_Q	266_I	0.784	0.80
701_L	706_A	0.783	0.80
1069_V	1076_Y	0.783	0.80
758_T	817_V	0.782	0.80
295_E	310_F	0.782	0.80
899_D	902_R	0.780	0.80
906_Y	910_Q	0.780	0.80
926_V	936_E	0.778	0.79
251_G	258_N	0.778	0.79
14_P	43_G	0.778	0.79
398_R	436_E	0.778	0.79
139_L	377_R	0.776	0.79
297_R	301_G	0.775	0.79
300_A	317_L	0.775	0.79
316_L	320_P	0.771	0.79
627_D	634_D	0.770	0.79
31_F	389_T	0.769	0.79
391_P	426_D	0.769	0.79
634_D	637_A	0.769	0.79
308_P	323_I	0.769	0.79
228_R	231_T	0.768	0.78
524_A	528_D	0.768	0.78
231_T	234_Q	0.767	0.78
153_I	158_L	0.767	0.78
127_F	130_H	0.766	0.78
660_M	664_L	0.766	0.78
1100_A	1103_Q	0.766	0.78
768_Y	771_R	0.765	0.78
60_L	125_A	0.765	0.78
647_G	651_I	0.764	0.78
698_G	702_E	0.764	0.78
161_Y	165_A	0.763	0.78
107_K	110_A	0.763	0.78
1010_S	1070_F	0.763	0.78
265_W	276_E	0.761	0.78
64_F	421_A	0.761	0.78
759_N	763_Q	0.759	0.78
257_F	260_S	0.759	0.78
641_V	644_E	0.759	0.78
258_N	263_A	0.759	0.78
530_L	554_I	0.759	0.78
1090_S	1102_M	0.758	0.78
250_S	253_D	0.758	0.78
599_L	645_F	0.757	0.77
423_R	458_N	0.757	0.77
309_L	312_A	0.756	0.77
495_T	501_M	0.756	0.77
904_T	909_L	0.755	0.77
171_H	174_P	0.755	0.77
197_I	332_L	0.754	0.77
929_A	938_P	0.754	0.77
530_L	549_V	0.753	0.77
282_L	287_E	0.753	0.77
245_A	249_S	0.752	0.77
689_H	692_E	0.752	0.77
266_I	501_M	0.751	0.77
312_A	318_A	0.751	0.77
37_Y	755_P	0.751	0.77
304_T	323_I	0.751	0.77
977_L	980_G	0.750	0.77
143_E	369_V	0.749	0.77
418_A	429_T	0.748	0.77
648_Y	668_R	0.748	0.77
830_D	846_E	0.747	0.77
490_V	499_M	0.747	0.77
386_F	394_Y	0.746	0.76
369_V	372_A	0.745	0.76
266_I	277_T	0.745	0.76
838_L	847_P	0.745	0.76
297_R	303_E	0.744	0.76
267_D	274_E	0.743	0.76
594_Q	598_W	0.743	0.76
154_E	158_L	0.742	0.76
690_I	694_L	0.740	0.76
62_V	132_F	0.740	0.76
503_L	506_G	0.738	0.76
382_M	951_P	0.737	0.76
368_E	371_A	0.737	0.76
13_L	16_Q	0.736	0.75
1109_L	1112_Q	0.735	0.75
129_I	409_L	0.733	0.75
303_E	314_D	0.733	0.75
257_F	261_N	0.733	0.75
129_I	389_T	0.732	0.75
615_A	618_T	0.732	0.75
643_E	646_D	0.730	0.75
710_W	714_H	0.730	0.75
62_V	130_H	0.730	0.75
20_L	411_L	0.729	0.75
306_R	309_L	0.729	0.75
558_V	740_T	0.727	0.75
1082_K	1114_Y	0.726	0.74
711_L	714_H	0.725	0.74
954_F	990_L	0.725	0.74
306_R	311_E	0.722	0.74
267_D	271_A	0.721	0.74
492_K	503_L	0.721	0.74
375_R	403_H	0.720	0.74
386_F	389_T	0.720	0.74
37_Y	394_Y	0.720	0.74
151_Q	348_E	0.720	0.74
434_R	440_H	0.719	0.74
396_I	410_L	0.718	0.74
30_T	63_T	0.718	0.74
602_A	649_R	0.717	0.74
1119_H	1129_Y	0.717	0.74
890_A	893_L	0.717	0.74
1126_I	1130_D	0.716	0.73
491_F	497_P	0.716	0.73
665_M	670_I	0.715	0.73
515_Q	566_Q	0.715	0.73
264_K	268_K	0.714	0.73
425_A	606_P	0.714	0.73
554_I	753_W	0.714	0.73
554_I	631_L	0.713	0.73
516_S	566_Q	0.712	0.73
929_A	934_V	0.712	0.73
411_L	433_A	0.712	0.73
703_S	706_A	0.711	0.73
293_F	303_E	0.711	0.73
349_L	357_R	0.711	0.73
130_H	133_C	0.710	0.73
1066_I	1118_L	0.710	0.73
919_D	923_R	0.710	0.73
127_F	131_G	0.709	0.73
64_F	74_G	0.707	0.73
602_A	612_L	0.705	0.72
76_I	744_S	0.704	0.72
43_G	54_L	0.703	0.72
753_W	816_G	0.702	0.72
599_L	603_V	0.702	0.72
655_R	659_P	0.701	0.72
141_A	144_S	0.701	0.72
305_P	319_E	0.701	0.72
727_M	735_L	0.700	0.72
129_I	397_F	0.700	0.72
394_Y	433_A	0.699	0.72
677_T	683_R	0.698	0.72
685_T	728_R	0.696	0.71
130_H	1021_M	0.695	0.71
302_G	308_P	0.695	0.71
1025_L	1120_R	0.695	0.71
491_F	503_L	0.695	0.71
137_L	349_L	0.694	0.71
239_A	246_L	0.693	0.71
355_L	423_R	0.691	0.71
489_F	499_M	0.691	0.71
77_R	124_A	0.690	0.71
25_A	68_A	0.690	0.71
255_R	260_S	0.690	0.71
926_V	930_G	0.689	0.71
27_T	38_L	0.689	0.71
901_W	906_Y	0.689	0.71
697_A	707_L	0.689	0.71
305_P	316_L	0.689	0.71
840_R	849_D	0.688	0.70
658_M	695_Q	0.688	0.70
66_E	396_I	0.688	0.70
163_A	335_I	0.687	0.70
164_C	168_W	0.687	0.70
373_A	376_T	0.686	0.70
117_A	415_P	0.685	0.70
791_E	795_L	0.682	0.70
865_I	869_T	0.682	0.70
558_V	561_R	0.680	0.70
518_M	758_T	0.680	0.70
952_G	956_H	0.680	0.70
126_V	1130_D	0.680	0.70
354_M	358_L	0.679	0.69
20_L	114_L	0.679	0.69
61_V	67_A	0.678	0.69
292_R	310_F	0.677	0.69
597_L	711_L	0.676	0.69
320_P	325_D	0.676	0.69
305_P	313_I	0.675	0.69
422_F	750_P	0.675	0.69
258_N	269_I	0.675	0.69
902_R	907_S	0.675	0.69
912_R	915_G	0.675	0.69
42_L	110_A	0.675	0.69
836_S	847_P	0.675	0.69
922_P	925_D	0.675	0.69
38_L	41_L	0.674	0.69
623_L	638_W	0.673	0.69
304_T	310_F	0.673	0.69
662_R	691_S	0.673	0.69
740_T	1079_L	0.672	0.69
731_S	737_Q	0.672	0.69
1101_A	1105_H	0.672	0.69
415_P	427_I	0.672	0.69
550_R	553_D	0.672	0.69
726_Q	735_L	0.671	0.69
56_V	132_F	0.671	0.69
390_D	427_I	0.671	0.69
302_G	314_D	0.670	0.68
584_R	657_V	0.669	0.68
37_Y	59_L	0.669	0.68
159_L	346_R	0.669	0.68
675_L	680_G	0.669	0.68
240_V	244_D	0.669	0.68
842_L	847_P	0.669	0.68
547_R	750_P	0.668	0.68
66_E	152_L	0.668	0.68
27_T	130_H	0.668	0.68
224_Q	233_K	0.667	0.68
518_M	959_F	0.667	0.68
41_L	54_L	0.667	0.68
454_V	457_V	0.667	0.68
599_L	618_T	0.667	0.68
316_L	319_E	0.666	0.68
356_S	392_Q	0.666	0.68
552_S	735_L	0.666	0.68
888_L	891_K	0.666	0.68
221_R	226_V	0.665	0.68
236_W	239_A	0.665	0.68
66_E	801_L	0.664	0.68
530_L	550_R	0.664	0.68
167_F	335_I	0.664	0.68
162_Q	709_R	0.663	0.68
958_L	962_L	0.662	0.68
1011_Q	1017_K	0.662	0.68
522_C	567_V	0.661	0.67
317_L	321_L	0.660	0.67
865_I	868_Q	0.660	0.67
222_H	226_V	0.660	0.67
409_L	430_Y	0.660	0.67
902_R	908_G	0.659	0.67
330_R	334_E	0.658	0.67
27_T	32_T	0.657	0.67
262_Q	277_T	0.656	0.67
788_D	792_A	0.656	0.67
237_R	241_G	0.656	0.67
976_K	982_F	0.656	0.67
958_L	994_I	0.655	0.67
974_R	987_E	0.654	0.67
381_A	627_D	0.654	0.67
281_Q	289_F	0.654	0.67
254_R	309_L	0.654	0.67
34_A	37_Y	0.653	0.66
777_V	780_L	0.653	0.66
839_G	846_E	0.653	0.66
21_I	593_A	0.651	0.66
991_T	994_I	0.650	0.66
769_H	775_E	0.650	0.66
301_G	305_P	0.650	0.66
515_Q	563_E	0.649	0.66
118_E	140_N	0.649	0.66
934_V	937_E	0.649	0.66
304_T	308_P	0.648	0.66
530_L	533_G	0.648	0.66
592_E	726_Q	0.648	0.66
238_D	249_S	0.647	0.66
993_W	997_V	0.647	0.66
178_E	326_L	0.646	0.66
341_R	344_R	0.646	0.66
55_T	116_L	0.645	0.66
452_G	455_N	0.645	0.66
568_R	572_T	0.645	0.66
462_S	527_R	0.644	0.65
60_L	738_I	0.644	0.65
400_I	620_M	0.644	0.65
105_D	109_Q	0.643	0.65
420_Y	423_R	0.643	0.65
225_I	229_I	0.643	0.65
513_D	516_S	0.642	0.65
287_E	290_S	0.642	0.65
379_P	401_W	0.641	0.65
757_I	816_G	0.640	0.65
456_S	499_M	0.640	0.65
33_I	412_I	0.639	0.65
490_V	497_P	0.637	0.65
951_P	1083_S	0.637	0.65
319_E	323_I	0.637	0.65
273_A	276_E	0.637	0.65
492_K	498_A	0.637	0.65
59_L	380_V	0.636	0.64
928_A	931_V	0.635	0.64
293_F	316_L	0.635	0.64
389_T	1069_V	0.634	0.64
215_D	337_E	0.634	0.64
1012_L	1017_K	0.634	0.64
948_G	1084_N	0.634	0.64
723_S	727_M	0.633	0.64
905_S	908_G	0.633	0.64
795_L	798_D	0.633	0.64
290_S	293_F	0.633	0.64
604_M	750_P	0.633	0.64
142_F	148_F	0.632	0.64
22_E	427_I	0.631	0.64
778_L	782_A	0.630	0.64
776_A	780_L	0.630	0.64
494_E	502_W	0.629	0.64
481_A	484_N	0.629	0.64
644_E	668_R	0.628	0.63
478_V	481_A	0.628	0.63
541_M	545_D	0.628	0.63
475_F	478_V	0.627	0.63
305_P	309_L	0.625	0.63
22_E	32_T	0.625	0.63
280_Y	283_P	0.625	0.63
21_I	358_L	0.623	0.63
975_E	978_E	0.623	0.63
24_S	31_F	0.623	0.63
143_E	373_A	0.622	0.63
556_V	753_W	0.622	0.63
596_M	665_M	0.620	0.62
215_D	219_A	0.620	0.62
527_R	551_A	0.620	0.62
352_D	390_D	0.620	0.62
32_T	443_L	0.620	0.62
262_Q	273_A	0.619	0.62
73_R	396_I	0.619	0.62
975_E	1074_G	0.619	0.62
307_H	320_P	0.619	0.62
22_E	390_D	0.619	0.62
268_K	276_E	0.619	0.62
683_R	686_D	0.618	0.62
18_E	141_A	0.618	0.62
299_K	304_T	0.617	0.62
1100_A	1104_A	0.617	0.62
303_E	323_I	0.617	0.62
286_L	296_D	0.616	0.62
730_E	733_K	0.616	0.62
268_K	272_W	0.615	0.62
649_R	653_R	0.615	0.62
561_R	743_K	0.615	0.62
693_L	710_W	0.615	0.62
294_L	297_R	0.614	0.62
130_H	392_Q	0.614	0.62
1102_M	1111_Y	0.614	0.62
883_V	886_A	0.614	0.62
1078_L	1128_D	0.613	0.62
933_S	937_E	0.613	0.62
921_M	925_D	0.613	0.62
588_F	686_D	0.612	0.61
256_K	259_R	0.611	0.61
320_P	323_I	0.611	0.61
577_P	736_V	0.611	0.61
304_T	325_D	0.610	0.61
932_A	935_V	0.610	0.61
64_F	423_R	0.609	0.61
1111_Y	1131_Y	0.609	0.61
661_L	694_L	0.609	0.61
771_R	774_F	0.609	0.61
261_N	266_I	0.609	0.61
221_R	232_V	0.609	0.61
568_R	580_Y	0.609	0.61
196_D	204_E	0.609	0.61
339_V	1069_V	0.608	0.61
743_K	1131_Y	0.608	0.61
281_Q	284_E	0.608	0.61
454_V	458_N	0.607	0.61
292_R	314_D	0.607	0.61
306_R	323_I	0.607	0.61
661_L	691_S	0.607	0.61
727_M	733_K	0.607	0.61
797_E	800_R	0.607	0.61
126_V	700_Q	0.605	0.61
421_A	794_R	0.604	0.60
951_P	954_F	0.603	0.60
298_T	304_T	0.603	0.60
416_K	461_F	0.603	0.60
306_R	312_A	0.602	0.60
235_Q	239_A	0.602	0.60
235_Q	238_D	0.602	0.60
998_L	1001_P	0.601	0.60
24_S	748_E	0.601	0.60
451_P	483_K	0.601	0.60
429_T	433_A	0.601	0.60
831_T	839_G	0.601	0.60
473_I	476_I	0.601	0.60
832_D	843_Q	0.601	0.60
262_Q	276_E	0.600	0.60
291_Q	300_A	0.600	0.60
308_P	319_E	0.599	0.60
133_C	354_M	0.599	0.60
512_G	516_S	0.598	0.60
167_F	330_R	0.598	0.60
377_R	1120_R	0.598	0.60
250_S	259_R	0.598	0.60
498_A	502_W	0.598	0.60
588_F	710_W	0.598	0.60
269_I	275_E	0.598	0.60
21_I	36_L	0.598	0.60
300_A	305_P	0.598	0.60
650_Q	873_G	0.598	0.60
933_S	938_P	0.598	0.60
892_T	898_G	0.597	0.60
291_Q	318_A	0.597	0.60
769_H	774_F	0.596	0.59
169_R	173_Y	0.596	0.59
558_V	563_E	0.596	0.59
425_A	617_A	0.596	0.59
587_V	693_L	0.595	0.59
450_A	748_E	0.595	0.59
73_R	456_S	0.595	0.59
410_L	425_A	0.595	0.59
894_Q	897_P	0.595	0.59
158_L	520_Q	0.594	0.59
478_V	482_G	0.594	0.59
984_S	1074_G	0.593	0.59
292_R	301_G	0.593	0.59
281_Q	287_E	0.592	0.59
283_P	291_Q	0.592	0.59
40_L	72_L	0.592	0.59
424_G	755_P	0.590	0.59
159_L	342_E	0.590	0.59
394_Y	411_L	0.590	0.59
55_T	113_W	0.590	0.59
60_L	127_F	0.590	0.59
767_F	770_D	0.589	0.59
378_F	381_A	0.589	0.59
915_G	919_D	0.589	0.59
665_M	671_A	0.588	0.58
1020_E	1080_D	0.587	0.58
69_T	127_F	0.587	0.58
401_W	409_L	0.586	0.58
211_P	333_A	0.586	0.58
882_D	1101_A	0.586	0.58
526_I	556_V	0.585	0.58
685_T	689_H	0.585	0.58
906_Y	909_L	0.585	0.58
227_A	231_T	0.585	0.58
272_W	275_E	0.584	0.58
491_F	499_M	0.583	0.58
529_W	554_I	0.583	0.58
305_P	317_L	0.582	0.58
559_R	743_K	0.581	0.58
587_V	1065_F	0.581	0.58
492_K	495_T	0.580	0.57
79_N	83_L	0.580	0.57
124_A	422_F	0.579	0.57
1080_D	1114_Y	0.579	0.57
495_T	500_K	0.579	0.57
392_Q	740_T	0.579	0.57
257_F	276_E	0.578	0.57
901_W	907_S	0.578	0.57
304_T	318_A	0.578	0.57
355_L	359_D	0.577	0.57
541_M	544_D	0.577	0.57
291_Q	301_G	0.577	0.57
802_L	815_L	0.577	0.57
60_L	72_L	0.577	0.57
38_L	117_A	0.577	0.57
76_I	665_M	0.577	0.57
869_T	872_T	0.576	0.57
123_E	381_A	0.576	0.57
67_A	739_V	0.576	0.57
968_V	999_Q	0.576	0.57
796_A	799_L	0.576	0.57
358_L	421_A	0.574	0.57
410_L	618_T	0.573	0.56
285_S	290_S	0.573	0.56
859_A	864_D	0.572	0.56
382_M	587_V	0.572	0.56
1075_R	1128_D	0.572	0.56
84_R	111_A	0.572	0.56
437_V	440_H	0.569	0.56
38_L	76_I	0.569	0.56
24_S	416_K	0.569	0.56
238_D	242_E	0.569	0.56
23_A	65_T	0.569	0.56
43_G	52_R	0.568	0.56
959_F	1081_Y	0.568	0.56
295_E	301_G	0.568	0.56
126_V	950_S	0.568	0.56
383_I	800_R	0.568	0.56
475_F	481_A	0.568	0.56
183_V	186_T	0.568	0.56
418_A	561_R	0.567	0.56
302_G	309_L	0.567	0.56
355_L	427_I	0.567	0.56
30_T	68_A	0.567	0.56
383_I	568_R	0.567	0.56
18_E	418_A	0.567	0.56
841_L	846_E	0.567	0.56
991_T	995_T	0.566	0.56
162_Q	346_R	0.566	0.56
37_Y	69_T	0.565	0.55
1122_L	1125_R	0.565	0.55
892_T	910_Q	0.564	0.55
493_G	500_K	0.564	0.55
791_E	794_R	0.564	0.55
299_K	313_I	0.564	0.55
932_A	938_P	0.563	0.55
644_E	647_G	0.563	0.55
397_F	738_I	0.563	0.55
567_V	755_P	0.562	0.55
178_E	181_Q	0.562	0.55
262_Q	272_W	0.561	0.55
125_A	382_M	0.561	0.55
84_R	118_E	0.561	0.55
593_A	707_L	0.560	0.55
952_G	1082_K	0.560	0.55
590_T	753_W	0.560	0.55
830_D	842_L	0.560	0.55
168_W	173_Y	0.560	0.55
299_K	306_R	0.560	0.55
1112_Q	1115_T	0.560	0.55
817_V	1062_L	0.560	0.55
255_R	267_D	0.559	0.55
948_G	1086_L	0.559	0.55
806_L	815_L	0.558	0.55
307_H	316_L	0.558	0.55
590_T	1069_V	0.558	0.55
108_A	112_Q	0.557	0.54
256_K	262_Q	0.557	0.54
24_S	114_L	0.557	0.54
121_M	1019_V	0.557	0.54
955_L	990_L	0.557	0.54
596_M	918_Q	0.556	0.54
907_S	919_D	0.556	0.54
300_A	310_F	0.556	0.54
25_A	416_K	0.556	0.54
221_R	233_K	0.555	0.54
766_A	774_F	0.555	0.54
884_S	893_L	0.554	0.54
110_A	373_A	0.554	0.54
81_H	85_I	0.554	0.54
754_L	806_L	0.553	0.54
162_Q	1089_D	0.553	0.54
349_L	358_L	0.553	0.54
314_D	321_L	0.553	0.54
117_A	355_L	0.553	0.54
1010_S	1077_Y	0.552	0.54
298_T	301_G	0.552	0.54
884_S	892_T	0.552	0.54
42_L	369_V	0.552	0.54
838_L	846_E	0.552	0.54
755_P	1068_L	0.552	0.54
118_E	121_M	0.551	0.54
606_P	610_N	0.551	0.54
798_D	801_L	0.551	0.54
226_V	230_D	0.551	0.54
295_E	312_A	0.550	0.53
162_Q	167_F	0.550	0.53
389_T	426_D	0.550	0.53
892_T	903_V	0.550	0.53
163_A	329_T	0.550	0.53
877_P	880_V	0.549	0.53
254_R	261_N	0.549	0.53
596_M	600_L	0.549	0.53
563_E	567_V	0.548	0.53
260_S	276_E	0.548	0.53
258_N	264_K	0.547	0.53
31_F	748_E	0.547	0.53
369_V	373_A	0.547	0.53
931_V	934_V	0.547	0.53
309_L	314_D	0.547	0.53
296_D	302_G	0.546	0.53
902_R	910_Q	0.546	0.53
27_T	433_A	0.545	0.53
994_I	998_L	0.545	0.53
133_C	797_E	0.545	0.53
25_A	65_T	0.545	0.53
295_E	311_E	0.545	0.53
1101_A	1104_A	0.545	0.53
1014_A	1017_K	0.544	0.53
462_S	477_P	0.544	0.53
579_V	582_S	0.544	0.53
446_N	749_Y	0.543	0.53
24_S	134_Q	0.543	0.53
926_V	931_V	0.543	0.53
794_R	798_D	0.543	0.53
930_G	933_S	0.542	0.52
317_L	323_I	0.542	0.52
394_Y	427_I	0.541	0.52
420_Y	461_F	0.541	0.52
20_L	32_T	0.541	0.52
921_M	926_V	0.541	0.52
837_A	848_Q	0.541	0.52
994_I	1003_N	0.540	0.52
308_P	317_L	0.540	0.52
792_A	796_A	0.540	0.52
690_I	693_L	0.540	0.52
616_L	623_L	0.540	0.52
597_L	708_V	0.540	0.52
127_F	139_L	0.540	0.52
518_M	558_V	0.539	0.52
988_P	992_E	0.539	0.52
265_W	288_K	0.539	0.52
155_D	744_S	0.539	0.52
907_S	979_L	0.539	0.52
952_G	1114_Y	0.538	0.52
445_T	479_K	0.538	0.52
27_T	36_L	0.538	0.52
225_I	242_E	0.537	0.52
915_G	922_P	0.536	0.52
454_V	483_K	0.536	0.52
360_S	1073_E	0.536	0.52
556_V	736_V	0.536	0.52
1080_D	1110_Q	0.535	0.52
31_F	79_N	0.535	0.52
875_N	920_L	0.535	0.52
446_N	741_I	0.535	0.52
700_Q	734_H	0.535	0.52
909_L	913_G	0.534	0.51
789_L	793_E	0.534	0.51
897_P	900_N	0.534	0.51
37_Y	41_L	0.534	0.51
285_S	288_K	0.534	0.51
476_I	480_S	0.533	0.51
224_Q	227_A	0.533	0.51
62_V	443_L	0.532	0.51
198_N	202_Q	0.532	0.51
304_T	309_L	0.532	0.51
555_S	739_V	0.531	0.51
596_M	994_I	0.531	0.51
67_A	117_A	0.531	0.51
493_G	502_W	0.530	0.51
998_L	1083_S	0.530	0.51
946_P	950_S	0.530	0.51
977_L	981_G	0.530	0.51
353_D	814_S	0.530	0.51
309_L	316_L	0.529	0.51
800_R	1064_G	0.528	0.51
1067_D	1082_K	0.528	0.51
295_E	321_L	0.528	0.51
27_T	1116_L	0.528	0.51
386_F	434_R	0.528	0.51
977_L	982_F	0.528	0.51
130_H	391_P	0.528	0.51
32_T	381_A	0.527	0.50
120_Q	123_E	0.527	0.50
23_A	63_T	0.527	0.50
154_E	351_F	0.527	0.50
171_H	175_L	0.527	0.50
600_L	604_M	0.527	0.50
561_R	564_A	0.526	0.50
295_E	300_A	0.526	0.50
398_R	403_H	0.525	0.50
935_V	942_P	0.525	0.50
303_E	317_L	0.525	0.50
956_H	1082_K	0.525	0.50
251_G	255_R	0.524	0.50
263_A	266_I	0.524	0.50
244_D	247_I	0.524	0.50
832_D	839_G	0.524	0.50
339_V	1111_Y	0.523	0.50
350_G	354_M	0.522	0.50
686_D	693_L	0.522	0.50
842_L	845_G	0.522	0.50
232_V	242_E	0.522	0.50
1076_Y	1124_H	0.522	0.50
415_P	429_T	0.522	0.50
133_C	355_L	0.521	0.50
450_A	453_M	0.521	0.50
1082_K	1110_Q	0.521	0.50
956_H	1080_D	0.521	0.50
32_T	343_K	0.520	0.50
141_A	389_T	0.520	0.50
929_A	932_A	0.520	0.50
31_F	744_S	0.520	0.50
206_P	598_W	0.520	0.50
200_Y	447_W	0.520	0.50
551_A	554_I	0.520	0.50
303_E	308_P	0.519	0.49
310_F	321_L	0.519	0.49
252_I	286_L	0.519	0.49
447_W	481_A	0.519	0.49
26_G	65_T	0.519	0.49
705_H	708_V	0.519	0.49
290_S	294_L	0.518	0.49
431_M	473_I	0.518	0.49
928_A	935_V	0.518	0.49
596_M	693_L	0.518	0.49
339_V	657_V	0.518	0.49
256_K	297_R	0.518	0.49
167_F	171_H	0.518	0.49
358_L	473_I	0.518	0.49
282_L	285_S	0.517	0.49
253_D	265_W	0.517	0.49
321_L	325_D	0.517	0.49
226_V	984_S	0.517	0.49
38_L	83_L	0.516	0.49
839_G	845_G	0.516	0.49
75_R	389_T	0.515	0.49
447_W	800_R	0.515	0.49
62_V	141_A	0.515	0.49
553_D	751_L	0.514	0.49
398_R	401_W	0.514	0.49
217_T	221_R	0.514	0.49
496_Q	500_K	0.513	0.49
32_T	427_I	0.513	0.49
286_L	313_I	0.513	0.49
27_T	37_Y	0.513	0.49
519_A	800_R	0.512	0.48
21_I	623_L	0.512	0.48
390_D	730_E	0.512	0.48
1126_I	1131_Y	0.512	0.48
24_S	564_A	0.511	0.48
394_Y	416_K	0.511	0.48
138_N	700_Q	0.511	0.48
233_K	243_L	0.511	0.48
30_T	75_R	0.511	0.48
1123_R	1126_I	0.510	0.48
164_C	167_F	0.510	0.48
73_R	688_L	0.510	0.48
65_T	71_E	0.510	0.48
36_L	380_V	0.510	0.48
310_F	316_L	0.509	0.48
382_M	679_G	0.509	0.48
587_V	1023_F	0.509	0.48
277_T	281_Q	0.509	0.48
316_L	321_L	0.509	0.48
137_L	368_E	0.509	0.48
32_T	141_A	0.508	0.48
230_D	234_Q	0.508	0.48
157_S	706_A	0.508	0.48
56_V	124_A	0.508	0.48
501_M	639_D	0.508	0.48
26_G	63_T	0.508	0.48
989_V	993_W	0.507	0.48
163_A	418_A	0.507	0.48
24_S	433_A	0.507	0.48
37_Y	67_A	0.507	0.48
241_G	271_A	0.507	0.48
836_S	864_D	0.506	0.48
361_A	374_I	0.506	0.48
647_G	663_A	0.505	0.48
978_E	994_I	0.505	0.48
492_K	528_D	0.505	0.48
210_A	356_S	0.505	0.48
477_P	482_G	0.505	0.48
727_M	730_E	0.505	0.48
129_I	383_I	0.504	0.47
694_L	697_A	0.504	0.47
219_A	296_D	0.504	0.47
612_L	645_F	0.504	0.47
252_I	265_W	0.503	0.47
21_I	335_I	0.503	0.47
389_T	400_I	0.503	0.47
120_Q	418_A	0.503	0.47
832_D	842_L	0.502	0.47
302_G	323_I	0.502	0.47
269_I	272_W	0.502	0.47
891_K	895_R	0.502	0.47
41_L	154_E	0.502	0.47
960_E	1130_D	0.502	0.47
832_D	841_L	0.502	0.47
378_F	396_I	0.502	0.47
262_Q	268_K	0.501	0.47
956_H	1114_Y	0.501	0.47
322_S	325_D	0.501	0.47
640_V	759_N	0.501	0.47
776_A	781_N	0.501	0.47
203_G	768_Y	0.500	0.47

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3u4qA	1	0.8508	100	0.316	Contact Map
1pjrA	1	0.4992	100	0.552	Contact Map
4c2tA	1	0.5195	100	0.554	Contact Map
1uaaA	2	0.5085	100	0.57	Contact Map
3lfuA	1	0.5059	100	0.58	Contact Map
4c2uA	1	0.5229	100	0.583	Contact Map
3u4qB	1	0.7627	100	0.606	Contact Map
4pj3A	1	0.4678	100	0.744	Contact Map
2xzlA	1	0.3653	100	0.787	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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