GREMLIN Database
CPDB - 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase
UniProt: P08331 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG10160
Length: 647 (497)
Sequences: 3528 (2506)
Seq/√Len: 112.4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
455_K533_P3.8101.00
452_K456_E3.7271.00
524_L531_I3.6511.00
498_Q523_N3.4421.00
211_E215_K3.3691.00
60_N334_D3.3651.00
448_K536_M3.3591.00
532_D535_A3.2601.00
29_T109_Y3.1211.00
175_G212_M3.1131.00
56_A60_N3.0251.00
357_G575_I2.9671.00
199_N204_T2.9261.00
342_K346_D2.9111.00
450_S453_E2.8891.00
503_Q519_E2.8371.00
72_V176_Y2.7881.00
175_G217_A2.6611.00
455_K524_L2.6441.00
500_D503_Q2.6401.00
244_L253_I2.6341.00
179_V205_V2.6191.00
355_P428_Q2.6161.00
338_V342_K2.5881.00
208_Y211_E2.5821.00
496_N525_T2.5381.00
111_V176_Y2.5101.00
145_A195_K2.5001.00
335_S339_E2.4991.00
206_R210_P2.3821.00
23_D301_Q2.3641.00
242_Y246_E2.3401.00
384_K493_D2.2611.00
421_Y424_V2.2501.00
26_I221_V2.2021.00
72_V223_L2.1781.00
158_K176_Y2.1621.00
525_T530_P2.1571.00
155_Y208_Y2.1501.00
71_L107_L2.1391.00
449_A539_V2.1301.00
26_I252_A2.1261.00
59_I71_L2.1231.00
105_N134_K2.0521.00
25_R299_D2.0501.00
459_E518_A2.0341.00
429_L575_I2.0191.00
71_L109_Y2.0021.00
209_V247_I1.9961.00
360_A586_H1.9891.00
213_R249_G1.9881.00
358_K428_Q1.9851.00
143_I199_N1.9651.00
72_V111_V1.9561.00
253_I285_A1.9511.00
252_A298_V1.9311.00
212_M217_A1.9201.00
106_T340_T1.9101.00
144_D147_T1.9091.00
139_N180_V1.9071.00
25_R297_V1.8941.00
157_I173_K1.8901.00
448_K538_L1.8811.00
504_P519_E1.8681.00
379_V414_R1.8681.00
385_A578_E1.8541.00
252_A284_P1.8521.00
58_L295_L1.8501.00
569_S573_A1.8301.00
449_A454_V1.8241.00
333_E338_V1.8241.00
213_R220_V1.8181.00
23_D299_D1.8081.00
62_A65_E1.8071.00
578_E583_G1.7991.00
252_A300_L1.7701.00
172_L219_V1.7701.00
28_E254_M1.7691.00
111_V138_V1.7451.00
356_I434_A1.7341.00
354_K576_A1.7301.00
66_V69_S1.7241.00
452_K533_P1.7131.00
222_V250_V1.7011.00
210_P214_E1.6951.00
454_V531_I1.6901.00
184_I198_V1.6741.00
205_V250_V1.6651.00
209_V220_V1.6581.00
30_T288_P1.6361.00
447_V546_A1.6161.00
29_T73_D1.5921.00
57_S61_D1.5901.00
503_Q522_K1.5801.00
204_T208_Y1.5751.00
498_Q594_R1.5581.00
53_V338_V1.5551.00
55_T295_L1.5471.00
450_S536_M1.5411.00
61_D65_E1.5401.00
408_P454_V1.5341.00
458_L524_L1.5281.00
457_W553_G1.5271.00
133_A137_Y1.5081.00
284_P314_A1.5071.00
73_D109_Y1.5051.00
406_A454_V1.5041.00
177_I205_V1.4901.00
385_A577_D1.4741.00
446_V538_L1.4571.00
101_Y133_A1.4431.00
74_N254_M1.4411.00
160_T174_I1.4371.00
145_A197_T1.4351.00
460_C553_G1.4331.00
27_M69_S1.4301.00
112_G135_F1.4241.00
58_L61_D1.4181.00
500_D520_R1.4101.00
78_I129_A1.3961.00
62_A297_V1.3911.00
101_Y105_N1.3881.00
452_K534_N1.3851.00
207_K211_E1.3801.00
459_E520_R1.3771.00
206_R248_P1.3761.00
297_V319_R1.3691.00
425_E433_N1.3641.00
26_I254_M1.3591.00
37_M345_H1.3491.00
247_I250_V1.3351.00
200_D203_E1.3251.00
381_N493_D1.3241.00
355_P430_T1.3201.00
254_M286_V1.3191.00
449_A453_E1.3171.00
105_N135_F1.3161.00
301_Q313_Q1.3121.00
433_N436_D1.3111.00
84_A121_Y1.3101.00
113_T138_V1.3091.00
62_A295_L1.3040.99
254_M298_V1.3030.99
53_V337_L1.2900.99
276_A282_G1.2870.99
70_V158_K1.2810.99
410_K413_G1.2790.99
303_S307_G1.2760.99
431_F572_A1.2720.99
63_R71_L1.2650.99
359_S429_L1.2650.99
500_D522_K1.2610.99
322_Y330_L1.2500.99
209_V250_V1.2480.99
381_N592_N1.2410.99
112_G137_Y1.2380.99
106_T336_K1.2320.99
289_G293_D1.2300.99
71_L295_L1.2250.99
120_N188_D1.2240.99
35_N291_W1.2240.99
499_I521_I1.2230.99
387_V446_V1.2140.99
143_I150_P1.2120.99
113_T178_G1.2110.99
209_V249_G1.2040.99
496_N528_G1.2020.99
55_T59_I1.1990.99
349_R353_S1.1960.99
258_A287_M1.1920.99
355_P358_K1.1920.99
28_E296_G1.1880.99
34_S84_A1.1870.99
114_L130_L1.1860.99
443_T543_N1.1840.99
155_Y175_G1.1820.99
32_L52_L1.1780.99
57_S331_A1.1760.99
139_N142_V1.1750.99
58_L331_A1.1720.99
111_V136_P1.1710.99
361_D587_P1.1650.99
217_A220_V1.1640.99
300_L311_V1.1640.99
140_A204_T1.1600.99
384_K388_E1.1550.99
498_Q522_K1.1540.99
532_D537_F1.1520.99
205_V222_V1.1520.99
143_I204_T1.1480.99
444_L540_A1.1480.99
383_Q407_A1.1430.99
206_R246_E1.1410.99
76_D116_N1.1370.99
159_D167_G1.1340.99
361_D374_P1.1340.99
462_A499_I1.1320.99
358_K584_E1.1290.99
529_K535_A1.1280.99
277_K280_L1.1260.98
153_T156_L1.1220.98
360_A587_P1.1200.98
199_N207_K1.1150.98
32_L292_G1.1080.98
182_P201_I1.1060.98
101_Y129_A1.1050.98
114_L152_F1.1020.98
372_D377_Q1.1020.98
25_R66_V1.0980.98
457_W554_T1.0910.98
56_A337_L1.0880.98
117_H120_N1.0840.98
212_M220_V1.0840.98
225_H257_H1.0830.98
219_V302_L1.0820.98
202_T246_E1.0800.98
275_I280_L1.0800.98
541_T546_A1.0740.98
60_N336_K1.0710.98
177_I208_Y1.0700.98
453_E556_D1.0670.98
70_V174_I1.0670.98
147_T150_P1.0640.98
21_T304_N1.0640.98
501_V595_L1.0600.98
421_Y426_K1.0590.98
177_I222_V1.0570.98
339_E342_K1.0490.98
33_H259_H1.0480.98
21_T301_Q1.0450.98
125_Y128_N1.0450.98
452_K455_K1.0440.98
159_D173_K1.0440.98
155_Y211_E1.0420.97
117_H225_H1.0370.97
359_S363_M1.0370.97
453_E557_S1.0350.97
203_E206_R1.0330.97
495_V526_F1.0320.97
566_E569_S1.0300.97
106_T337_L1.0290.97
58_L321_I1.0260.97
377_Q590_D1.0240.97
30_T287_M1.0240.97
226_S243_Y1.0210.97
65_E297_V1.0170.97
111_V156_L1.0170.97
73_D77_L1.0120.97
526_F537_F1.0110.97
359_S362_N1.0090.97
57_S332_A1.0080.97
407_A410_K1.0050.97
27_M297_V0.9980.97
578_E584_E0.9980.97
286_V298_V0.9950.97
490_D545_R0.9920.97
130_L137_Y0.9880.97
450_S534_N0.9870.97
575_I585_I0.9870.97
70_V176_Y0.9860.96
462_A497_Y0.9830.96
33_H257_H0.9810.96
154_P208_Y0.9810.96
362_N426_K0.9780.96
530_P533_P0.9770.96
27_M62_A0.9770.96
150_P204_T0.9760.96
105_N133_A0.9730.96
297_V317_E0.9660.96
188_D192_L0.9640.96
498_Q596_A0.9620.96
405_A535_A0.9580.96
379_V438_Y0.9530.96
303_S312_T0.9510.96
176_Y223_L0.9500.96
290_M293_D0.9490.96
382_A574_W0.9490.96
443_T562_A0.9460.96
289_G294_H0.9460.96
406_A539_V0.9400.95
461_S490_D0.9360.95
116_N257_H0.9330.95
28_E74_N0.9330.95
156_L160_T0.9300.95
345_H349_R0.9300.95
242_Y245_S0.9300.95
25_R62_A0.9290.95
440_Y544_Y0.9270.95
221_V252_A0.9260.95
490_D551_F0.9250.95
533_P537_F0.9250.95
76_D225_H0.9250.95
182_P200_D0.9250.95
59_I63_R0.9230.95
201_I243_Y0.9200.95
261_V289_G0.9180.95
172_L218_D0.9180.95
385_A574_W0.9150.95
72_V254_M0.9130.95
232_P285_A0.9120.95
29_T71_L0.9060.94
286_V296_G0.9050.94
155_Y159_D0.9040.94
104_L109_Y0.9030.94
103_A337_L0.9010.94
409_F413_G0.8970.94
157_I217_A0.8960.94
58_L319_R0.8950.94
52_L341_L0.8930.94
56_A334_D0.8900.94
376_V491_V0.8900.94
354_K431_F0.8890.94
179_V224_A0.8890.94
384_K538_L0.8890.94
413_G440_Y0.8890.94
301_Q312_T0.8890.94
277_K281_N0.8880.94
389_H540_A0.8850.94
176_Y221_V0.8840.94
59_I107_L0.8830.94
572_A576_A0.8830.94
58_L62_A0.8820.94
150_P208_Y0.8810.94
409_F412_G0.8790.93
492_I495_V0.8730.93
442_N542_N0.8730.93
227_G258_A0.8730.93
61_D331_A0.8710.93
26_I70_V0.8650.93
406_A495_V0.8640.93
412_G440_Y0.8640.93
346_D350_Q0.8600.93
160_T176_Y0.8600.93
448_K559_I0.8590.93
32_L100_V0.8580.93
413_G442_N0.8560.93
311_V314_A0.8560.93
453_E553_G0.8560.93
104_L135_F0.8540.92
76_D117_H0.8530.92
503_Q518_A0.8510.92
553_G556_D0.8510.92
142_V180_V0.8510.92
548_G551_F0.8500.92
123_L127_K0.8500.92
33_H227_G0.8470.92
208_Y212_M0.8460.92
363_M374_P0.8450.92
61_D64_N0.8430.92
382_A570_V0.8350.92
302_L311_V0.8330.91
573_A576_A0.8320.91
13_I16_S0.8310.91
411_V487_Y0.8300.91
455_K519_E0.8300.91
31_D259_H0.8280.91
451_G537_F0.8270.91
434_A568_R0.8270.91
174_I221_V0.8260.91
54_R333_E0.8260.91
24_L174_I0.8250.91
98_H102_K0.8240.91
53_V333_E0.8240.91
203_E207_K0.8220.91
261_V294_H0.8210.91
159_D174_I0.8210.91
252_A314_A0.8200.91
142_V196_V0.8190.91
177_I212_M0.8180.91
573_A577_D0.8160.91
116_N225_H0.8150.91
24_L300_L0.8150.91
177_I250_V0.8140.91
386_Y573_A0.8130.90
376_V414_R0.8090.90
220_V249_G0.8070.90
187_W257_H0.8050.90
454_V458_L0.8040.90
356_I572_A0.8040.90
73_D113_T0.8030.90
458_L497_Y0.8020.90
504_P518_A0.8010.90
459_E521_I0.7990.90
227_G257_H0.7980.90
337_L340_T0.7960.90
123_L195_K0.7960.90
351_F354_K0.7940.89
406_A409_F0.7930.89
38_D333_E0.7930.89
102_K344_D0.7910.89
403_L406_A0.7900.89
142_V198_V0.7890.89
442_N543_N0.7890.89
406_A526_F0.7890.89
343_A347_A0.7880.89
202_T206_R0.7880.89
383_Q438_Y0.7880.89
61_D332_A0.7880.89
487_Y490_D0.7880.89
360_A584_E0.7880.89
70_V160_T0.7870.89
224_A255_F0.7860.89
25_R69_S0.7850.89
98_H128_N0.7800.89
383_Q542_N0.7800.89
143_I197_T0.7780.88
375_T437_L0.7750.88
449_A554_T0.7740.88
224_A253_I0.7720.88
113_T223_L0.7710.88
155_Y160_T0.7670.88
544_Y549_G0.7640.88
385_A389_H0.7640.88
185_M198_V0.7630.87
29_T55_T0.7630.87
155_Y158_K0.7620.87
114_L119_F0.7570.87
123_L196_V0.7560.87
240_S255_F0.7560.87
454_V539_V0.7550.87
102_K340_T0.7540.87
225_H259_H0.7520.87
503_Q520_R0.7490.86
116_N259_H0.7480.86
33_H80_G0.7470.86
454_V495_V0.7470.86
73_D104_L0.7460.86
117_H259_H0.7450.86
110_T160_T0.7430.86
22_V166_D0.7420.86
205_V247_I0.7410.86
128_N131_A0.7380.86
490_D497_Y0.7370.86
76_D257_H0.7360.86
120_N184_I0.7350.85
188_D193_S0.7350.85
460_C463_G0.7350.85
209_V213_R0.7350.85
212_M216_G0.7320.85
445_I546_A0.7300.85
33_H225_H0.7300.85
199_N203_E0.7290.85
77_L112_G0.7260.85
117_H257_H0.7260.85
55_T71_L0.7260.85
504_P520_R0.7260.85
453_E456_E0.7240.85
193_S198_V0.7230.85
12_L15_A0.7220.84
76_D259_H0.7220.84
461_S464_Q0.7220.84
438_Y571_L0.7200.84
66_V299_D0.7200.84
368_A373_D0.7190.84
55_T292_G0.7170.84
438_Y567_N0.7170.84
380_N407_A0.7160.84
463_G505_A0.7160.84
422_V436_D0.7160.84
374_P377_Q0.7150.84
408_P539_V0.7150.84
458_L521_I0.7140.84
380_N406_A0.7100.83
109_Y112_G0.7100.83
13_I17_V0.7100.83
459_E504_P0.7070.83
74_N113_T0.7070.83
261_V318_A0.7050.83
378_V382_A0.7040.83
381_N385_A0.7040.83
87_M347_A0.7030.83
52_L103_A0.6990.82
68_N166_D0.6980.82
456_E553_G0.6980.82
387_V540_A0.6970.82
128_N132_G0.6940.82
406_A412_G0.6920.82
24_L172_L0.6920.82
280_L285_A0.6900.82
177_I209_V0.6900.82
35_N81_S0.6890.82
499_I595_L0.6880.81
56_A107_L0.6880.81
113_T139_N0.6880.81
14_A17_V0.6870.81
38_D54_R0.6870.81
116_N120_N0.6860.81
205_V243_Y0.6840.81
32_L77_L0.6830.81
125_Y129_A0.6820.81
27_M71_L0.6810.81
149_Q214_E0.6810.81
156_L176_Y0.6810.81
407_A412_G0.6790.81
434_A572_A0.6780.81
140_A178_G0.6770.80
114_L137_Y0.6730.80
181_P184_I0.6710.80
274_D277_K0.6700.80
33_H79_Q0.6700.80
136_P156_L0.6680.80
111_V223_L0.6680.80
244_L285_A0.6660.79
356_I575_I0.6640.79
103_A341_L0.6640.79
204_T207_K0.6620.79
34_S100_V0.6620.79
353_S432_R0.6600.79
63_R110_T0.6600.79
87_M344_D0.6580.79
32_L109_Y0.6580.79
523_N531_I0.6580.79
210_P248_P0.6570.78
494_G526_F0.6560.78
413_G544_Y0.6520.78
383_Q567_N0.6510.78
448_K558_H0.6490.78
62_A319_R0.6480.77
389_H404_S0.6470.77
277_K283_V0.6470.77
77_L104_L0.6470.77
12_L17_V0.6470.77
21_T312_T0.6460.77
15_A18_N0.6460.77
336_K339_E0.6450.77
12_L18_N0.6450.77
460_C551_F0.6440.77
489_F492_I0.6430.77
238_E241_V0.6410.77
361_D426_K0.6410.77
119_F126_L0.6410.77
241_V245_S0.6390.77
377_Q592_N0.6380.76
280_L283_V0.6370.76
254_M296_G0.6350.76
144_D149_Q0.6330.76
146_R197_T0.6330.76
52_L55_T0.6320.76
279_T282_G0.6310.76
524_L533_P0.6300.76
533_P536_M0.6300.76
406_A537_F0.6290.75
212_M215_K0.6280.75
358_K583_G0.6270.75
255_F287_M0.6270.75
458_L492_I0.6260.75
457_W539_V0.6260.75
185_M196_V0.6260.75
33_H116_N0.6260.75
130_L138_V0.6250.75
543_N567_N0.6250.75
219_V300_L0.6220.75
441_P568_R0.6210.74
33_H76_D0.6210.74
188_D544_Y0.6210.74
447_V541_T0.6200.74
240_S285_A0.6200.74
455_K531_I0.6190.74
386_Y570_V0.6180.74
186_G550_K0.6160.74
88_S121_Y0.6160.74
363_M378_V0.6150.74
407_A542_N0.6130.74
179_V243_Y0.6120.73
346_D349_R0.6120.73
316_A321_I0.6120.73
372_D493_D0.6110.73
172_L302_L0.6110.73
114_L126_L0.6100.73
87_M99_P0.6090.73
274_D282_G0.6080.73
505_A518_A0.6080.73
154_P160_T0.6080.73
191_N194_G0.6070.73
571_L575_I0.6070.73
140_A205_V0.6070.73
25_R65_E0.6070.73
30_T439_L0.6060.73
565_D570_V0.6050.73
206_R247_I0.6050.73
454_V533_P0.6040.72
175_G216_G0.6030.72
386_Y565_D0.6020.72
458_L495_V0.6010.72
219_V311_V0.6010.72
408_P457_W0.6010.72
370_V539_V0.5990.72
201_I204_T0.5980.72
410_K442_N0.5980.72
33_H287_M0.5960.71
380_N409_F0.5950.71
79_Q227_G0.5930.71
352_V432_R0.5920.71
460_C488_N0.5920.71
74_N223_L0.5920.71
154_P157_I0.5920.71
377_Q493_D0.5910.71
406_A494_G0.5890.71
32_L104_L0.5870.70
299_D315_K0.5850.70
350_Q353_S0.5840.70
542_N545_R0.5840.70
303_S306_S0.5840.70
33_H117_H0.5810.70
155_Y215_K0.5790.69
89_A99_P0.5760.69
443_T566_E0.5750.69
193_S196_V0.5750.69
63_R107_L0.5750.69
63_R108_D0.5750.69
38_D50_F0.5750.69
238_E243_Y0.5730.68
409_F567_N0.5730.68
409_F442_N0.5730.68
223_L254_M0.5730.68
21_T303_S0.5730.68
134_K213_R0.5720.68
173_K218_D0.5720.68
422_V425_E0.5710.68
425_E428_Q0.5710.68
12_L19_A0.5700.68
541_T554_T0.5690.68
173_K215_K0.5670.68
74_N259_H0.5670.68
248_P283_V0.5670.68
57_S60_N0.5660.68
175_G208_Y0.5660.68
238_E244_L0.5640.67
430_T433_N0.5630.67
531_I537_F0.5630.67
565_D573_A0.5620.67
129_A133_A0.5620.67
228_L232_P0.5620.67
72_V158_K0.5610.67
372_D590_D0.5600.67
357_G578_E0.5590.67
12_L16_S0.5590.67
332_A335_S0.5580.66
183_Q186_G0.5570.66
294_H320_P0.5560.66
179_V222_V0.5550.66
59_I295_L0.5550.66
295_L319_R0.5540.66
460_C550_K0.5540.66
98_H132_G0.5530.66
60_N64_N0.5520.66
30_T74_N0.5520.66
138_V156_L0.5520.66
77_L109_Y0.5510.65
54_R321_I0.5510.65
143_I148_K0.5510.65
496_N523_N0.5500.65
143_I208_Y0.5490.65
237_A243_Y0.5490.65
228_L240_S0.5480.65
79_Q257_H0.5480.65
409_F438_Y0.5470.65
73_D112_G0.5470.65
372_D592_N0.5460.65
434_A575_I0.5460.65
36_M341_L0.5460.65
152_F253_I0.5460.65
384_K407_A0.5460.65
120_N225_H0.5440.64
532_D536_M0.5440.64
239_N242_Y0.5430.64
490_D493_D0.5430.64
24_L302_L0.5420.64
140_A154_P0.5420.64
210_P217_A0.5420.64
410_K439_L0.5410.64
148_K197_T0.5400.64
181_P287_M0.5390.64
382_A571_L0.5380.64
22_V172_L0.5380.64
406_A411_V0.5380.64
230_A242_Y0.5380.64
302_L306_S0.5380.64
84_A88_S0.5380.64
405_A411_V0.5380.64
117_H440_Y0.5370.63
369_L487_Y0.5360.63
424_V427_G0.5360.63
248_P279_T0.5350.63
73_D80_G0.5340.63
575_I583_G0.5340.63
255_F258_A0.5330.63
369_L411_V0.5330.63
227_G259_H0.5320.63
160_T208_Y0.5320.63
414_R491_V0.5310.63
231_D255_F0.5300.62
102_K343_A0.5300.62
114_L138_V0.5300.62
210_P249_G0.5290.62
362_N425_E0.5270.62
588_A591_N0.5270.62
201_I226_S0.5270.62
389_H577_D0.5270.62
404_S409_F0.5260.62
372_D591_N0.5260.62
239_N244_L0.5250.62
173_K216_G0.5250.62
18_N21_T0.5240.62
84_A89_A0.5230.61
54_R331_A0.5230.61
184_I187_W0.5230.61
386_Y444_L0.5220.61
259_H290_M0.5220.61
29_T32_L0.5220.61
85_D441_P0.5210.61
444_L570_V0.5210.61
560_A563_S0.5210.61
78_I118_E0.5200.61
423_E426_K0.5200.61
376_V380_N0.5200.61
365_S373_D0.5190.61
80_G227_G0.5180.61
184_I188_D0.5180.61
79_Q118_E0.5170.61
20_A304_N0.5170.61
24_L251_N0.5170.61
157_I175_G0.5160.60
552_A555_G0.5140.60
245_S281_N0.5110.60
35_N80_G0.5110.60
255_F285_A0.5110.60
74_N288_P0.5110.60
63_R66_V0.5110.60
413_G542_N0.5100.60
102_K106_T0.5100.60
63_R69_S0.5090.59
236_M241_V0.5080.59
102_K337_L0.5060.59
408_P411_V0.5050.59
112_G133_A0.5040.59
228_L262_F0.5040.59
107_L198_V0.5030.59
31_D257_H0.5030.59
407_A540_A0.5020.58
182_P226_S0.5020.58
144_D148_K0.5020.58
72_V221_V0.5010.58
110_T158_K0.5010.58
185_M193_S0.5010.58
202_T247_I0.5000.58
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2z1aA 1 0.7573 100 0.322 Contact Map
4h2gA 2 0.7651 100 0.342 Contact Map
3ztvA 2 0.7682 100 0.347 Contact Map
4q7fA 1 0.7666 100 0.348 Contact Map
3iveA 1 0.7434 100 0.351 Contact Map
1hp1A 1 0.7635 100 0.369 Contact Map
2wdcA 1 0.7527 100 0.383 Contact Map
3c9fA 2 0.7697 100 0.513 Contact Map
3jyfA 2 0.5193 100 0.576 Contact Map
3gveA 2 0.5085 100 0.585 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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