CPDB - ECOLI - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

CPDB - 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase

UniProt:	P08331	Sequences: MIKFSATLLATLIAASVNAATVDLRIMETTDLHSNMMDFDYYKDTATEKFGLVRTASLINDARNEVKNSVLVDNGDLIQGSPLADYMSAKGLKAGDIHPVYKALNTLDYTVGTLGNHEFNYGLDYLKNALAGAKFPYVNANVIDARTKQPMFTPYLIKDTEVVDKDGKKQTLKIGYIGVVPPQIMGWDKANLSGKVTVNDITETVRKYVPEMREKGADVVVVLAHSGLSADPYKVMAENSVYYLSEIPGVNAIMFGHAHAVFPGKDFADIEGADIAKGTLNGVPAVMPGMWGDHLGVVDLQLSNDSGKWQVTQAKAEARPIYDIANKKSLAAEDSKLVETLKADHDATRQFVSKPIGKSADNMYSYLALVQDDPTVQVVNNAQKAYVEHYIQGDPDLAKLPVLSAAAPFKVGGRKNDPASYVEVEKGQLTFRNAADLYLYPNTLIVVKASGKEVKEWLECSAGQFNQIDPNSTKPQSLINWDGFRTYNFDVIDGVNYQIDVTQPARYDGECQMINANAERIKNLTFNGKPIDPNAMFLVATNNYRAYGGKFAGTGDSHIAFASPDENRSVLAAWIADESKRAGEIHPAADNNWRLAPIAGDKKLDIRFETSPSDKAAAFIKEKGQYPMNKVATDDIGFAIYQVDLSK	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10160
Length:	647 (497)
Sequences:	3528 (2506)
Seq/√Len:	112.4

ECOLI - CPDB USHA
BACSU - NTPES YUND YHCR
HALSA - Q9HPZ0 Q9HPW1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
455_K	533_P	3.810	1.00
452_K	456_E	3.727	1.00
524_L	531_I	3.651	1.00
498_Q	523_N	3.442	1.00
211_E	215_K	3.369	1.00
60_N	334_D	3.365	1.00
448_K	536_M	3.359	1.00
532_D	535_A	3.260	1.00
29_T	109_Y	3.121	1.00
175_G	212_M	3.113	1.00
56_A	60_N	3.025	1.00
357_G	575_I	2.967	1.00
199_N	204_T	2.926	1.00
342_K	346_D	2.911	1.00
450_S	453_E	2.889	1.00
503_Q	519_E	2.837	1.00
72_V	176_Y	2.788	1.00
175_G	217_A	2.661	1.00
455_K	524_L	2.644	1.00
500_D	503_Q	2.640	1.00
244_L	253_I	2.634	1.00
179_V	205_V	2.619	1.00
355_P	428_Q	2.616	1.00
338_V	342_K	2.588	1.00
208_Y	211_E	2.582	1.00
496_N	525_T	2.538	1.00
111_V	176_Y	2.510	1.00
145_A	195_K	2.500	1.00
335_S	339_E	2.499	1.00
206_R	210_P	2.382	1.00
23_D	301_Q	2.364	1.00
242_Y	246_E	2.340	1.00
384_K	493_D	2.261	1.00
421_Y	424_V	2.250	1.00
26_I	221_V	2.202	1.00
72_V	223_L	2.178	1.00
158_K	176_Y	2.162	1.00
525_T	530_P	2.157	1.00
155_Y	208_Y	2.150	1.00
71_L	107_L	2.139	1.00
449_A	539_V	2.130	1.00
26_I	252_A	2.126	1.00
59_I	71_L	2.123	1.00
105_N	134_K	2.052	1.00
25_R	299_D	2.050	1.00
459_E	518_A	2.034	1.00
429_L	575_I	2.019	1.00
71_L	109_Y	2.002	1.00
209_V	247_I	1.996	1.00
360_A	586_H	1.989	1.00
213_R	249_G	1.988	1.00
358_K	428_Q	1.985	1.00
143_I	199_N	1.965	1.00
72_V	111_V	1.956	1.00
253_I	285_A	1.951	1.00
252_A	298_V	1.931	1.00
212_M	217_A	1.920	1.00
106_T	340_T	1.910	1.00
144_D	147_T	1.909	1.00
139_N	180_V	1.907	1.00
25_R	297_V	1.894	1.00
157_I	173_K	1.890	1.00
448_K	538_L	1.881	1.00
504_P	519_E	1.868	1.00
379_V	414_R	1.868	1.00
385_A	578_E	1.854	1.00
252_A	284_P	1.852	1.00
58_L	295_L	1.850	1.00
569_S	573_A	1.830	1.00
449_A	454_V	1.824	1.00
333_E	338_V	1.824	1.00
213_R	220_V	1.818	1.00
23_D	299_D	1.808	1.00
62_A	65_E	1.807	1.00
578_E	583_G	1.799	1.00
252_A	300_L	1.770	1.00
172_L	219_V	1.770	1.00
28_E	254_M	1.769	1.00
111_V	138_V	1.745	1.00
356_I	434_A	1.734	1.00
354_K	576_A	1.730	1.00
66_V	69_S	1.724	1.00
452_K	533_P	1.713	1.00
222_V	250_V	1.701	1.00
210_P	214_E	1.695	1.00
454_V	531_I	1.690	1.00
184_I	198_V	1.674	1.00
205_V	250_V	1.665	1.00
209_V	220_V	1.658	1.00
30_T	288_P	1.636	1.00
447_V	546_A	1.616	1.00
29_T	73_D	1.592	1.00
57_S	61_D	1.590	1.00
503_Q	522_K	1.580	1.00
204_T	208_Y	1.575	1.00
498_Q	594_R	1.558	1.00
53_V	338_V	1.555	1.00
55_T	295_L	1.547	1.00
450_S	536_M	1.541	1.00
61_D	65_E	1.540	1.00
408_P	454_V	1.534	1.00
458_L	524_L	1.528	1.00
457_W	553_G	1.527	1.00
133_A	137_Y	1.508	1.00
284_P	314_A	1.507	1.00
73_D	109_Y	1.505	1.00
406_A	454_V	1.504	1.00
177_I	205_V	1.490	1.00
385_A	577_D	1.474	1.00
446_V	538_L	1.457	1.00
101_Y	133_A	1.443	1.00
74_N	254_M	1.441	1.00
160_T	174_I	1.437	1.00
145_A	197_T	1.435	1.00
460_C	553_G	1.433	1.00
27_M	69_S	1.430	1.00
112_G	135_F	1.424	1.00
58_L	61_D	1.418	1.00
500_D	520_R	1.410	1.00
78_I	129_A	1.396	1.00
62_A	297_V	1.391	1.00
101_Y	105_N	1.388	1.00
452_K	534_N	1.385	1.00
207_K	211_E	1.380	1.00
459_E	520_R	1.377	1.00
206_R	248_P	1.376	1.00
297_V	319_R	1.369	1.00
425_E	433_N	1.364	1.00
26_I	254_M	1.359	1.00
37_M	345_H	1.349	1.00
247_I	250_V	1.335	1.00
200_D	203_E	1.325	1.00
381_N	493_D	1.324	1.00
355_P	430_T	1.320	1.00
254_M	286_V	1.319	1.00
449_A	453_E	1.317	1.00
105_N	135_F	1.316	1.00
301_Q	313_Q	1.312	1.00
433_N	436_D	1.311	1.00
84_A	121_Y	1.310	1.00
113_T	138_V	1.309	1.00
62_A	295_L	1.304	0.99
254_M	298_V	1.303	0.99
53_V	337_L	1.290	0.99
276_A	282_G	1.287	0.99
70_V	158_K	1.281	0.99
410_K	413_G	1.279	0.99
303_S	307_G	1.276	0.99
431_F	572_A	1.272	0.99
63_R	71_L	1.265	0.99
359_S	429_L	1.265	0.99
500_D	522_K	1.261	0.99
322_Y	330_L	1.250	0.99
209_V	250_V	1.248	0.99
381_N	592_N	1.241	0.99
112_G	137_Y	1.238	0.99
106_T	336_K	1.232	0.99
289_G	293_D	1.230	0.99
71_L	295_L	1.225	0.99
120_N	188_D	1.224	0.99
35_N	291_W	1.224	0.99
499_I	521_I	1.223	0.99
387_V	446_V	1.214	0.99
143_I	150_P	1.212	0.99
113_T	178_G	1.211	0.99
209_V	249_G	1.204	0.99
496_N	528_G	1.202	0.99
55_T	59_I	1.199	0.99
349_R	353_S	1.196	0.99
258_A	287_M	1.192	0.99
355_P	358_K	1.192	0.99
28_E	296_G	1.188	0.99
34_S	84_A	1.187	0.99
114_L	130_L	1.186	0.99
443_T	543_N	1.184	0.99
155_Y	175_G	1.182	0.99
32_L	52_L	1.178	0.99
57_S	331_A	1.176	0.99
139_N	142_V	1.175	0.99
58_L	331_A	1.172	0.99
111_V	136_P	1.171	0.99
361_D	587_P	1.165	0.99
217_A	220_V	1.164	0.99
300_L	311_V	1.164	0.99
140_A	204_T	1.160	0.99
384_K	388_E	1.155	0.99
498_Q	522_K	1.154	0.99
532_D	537_F	1.152	0.99
205_V	222_V	1.152	0.99
143_I	204_T	1.148	0.99
444_L	540_A	1.148	0.99
383_Q	407_A	1.143	0.99
206_R	246_E	1.141	0.99
76_D	116_N	1.137	0.99
159_D	167_G	1.134	0.99
361_D	374_P	1.134	0.99
462_A	499_I	1.132	0.99
358_K	584_E	1.129	0.99
529_K	535_A	1.128	0.99
277_K	280_L	1.126	0.98
153_T	156_L	1.122	0.98
360_A	587_P	1.120	0.98
199_N	207_K	1.115	0.98
32_L	292_G	1.108	0.98
182_P	201_I	1.106	0.98
101_Y	129_A	1.105	0.98
114_L	152_F	1.102	0.98
372_D	377_Q	1.102	0.98
25_R	66_V	1.098	0.98
457_W	554_T	1.091	0.98
56_A	337_L	1.088	0.98
117_H	120_N	1.084	0.98
212_M	220_V	1.084	0.98
225_H	257_H	1.083	0.98
219_V	302_L	1.082	0.98
202_T	246_E	1.080	0.98
275_I	280_L	1.080	0.98
541_T	546_A	1.074	0.98
60_N	336_K	1.071	0.98
177_I	208_Y	1.070	0.98
453_E	556_D	1.067	0.98
70_V	174_I	1.067	0.98
147_T	150_P	1.064	0.98
21_T	304_N	1.064	0.98
501_V	595_L	1.060	0.98
421_Y	426_K	1.059	0.98
177_I	222_V	1.057	0.98
339_E	342_K	1.049	0.98
33_H	259_H	1.048	0.98
21_T	301_Q	1.045	0.98
125_Y	128_N	1.045	0.98
452_K	455_K	1.044	0.98
159_D	173_K	1.044	0.98
155_Y	211_E	1.042	0.97
117_H	225_H	1.037	0.97
359_S	363_M	1.037	0.97
453_E	557_S	1.035	0.97
203_E	206_R	1.033	0.97
495_V	526_F	1.032	0.97
566_E	569_S	1.030	0.97
106_T	337_L	1.029	0.97
58_L	321_I	1.026	0.97
377_Q	590_D	1.024	0.97
30_T	287_M	1.024	0.97
226_S	243_Y	1.021	0.97
65_E	297_V	1.017	0.97
111_V	156_L	1.017	0.97
73_D	77_L	1.012	0.97
526_F	537_F	1.011	0.97
359_S	362_N	1.009	0.97
57_S	332_A	1.008	0.97
407_A	410_K	1.005	0.97
27_M	297_V	0.998	0.97
578_E	584_E	0.998	0.97
286_V	298_V	0.995	0.97
490_D	545_R	0.992	0.97
130_L	137_Y	0.988	0.97
450_S	534_N	0.987	0.97
575_I	585_I	0.987	0.97
70_V	176_Y	0.986	0.96
462_A	497_Y	0.983	0.96
33_H	257_H	0.981	0.96
154_P	208_Y	0.981	0.96
362_N	426_K	0.978	0.96
530_P	533_P	0.977	0.96
27_M	62_A	0.977	0.96
150_P	204_T	0.976	0.96
105_N	133_A	0.973	0.96
297_V	317_E	0.966	0.96
188_D	192_L	0.964	0.96
498_Q	596_A	0.962	0.96
405_A	535_A	0.958	0.96
379_V	438_Y	0.953	0.96
303_S	312_T	0.951	0.96
176_Y	223_L	0.950	0.96
290_M	293_D	0.949	0.96
382_A	574_W	0.949	0.96
443_T	562_A	0.946	0.96
289_G	294_H	0.946	0.96
406_A	539_V	0.940	0.95
461_S	490_D	0.936	0.95
116_N	257_H	0.933	0.95
28_E	74_N	0.933	0.95
156_L	160_T	0.930	0.95
345_H	349_R	0.930	0.95
242_Y	245_S	0.930	0.95
25_R	62_A	0.929	0.95
440_Y	544_Y	0.927	0.95
221_V	252_A	0.926	0.95
490_D	551_F	0.925	0.95
533_P	537_F	0.925	0.95
76_D	225_H	0.925	0.95
182_P	200_D	0.925	0.95
59_I	63_R	0.923	0.95
201_I	243_Y	0.920	0.95
261_V	289_G	0.918	0.95
172_L	218_D	0.918	0.95
385_A	574_W	0.915	0.95
72_V	254_M	0.913	0.95
232_P	285_A	0.912	0.95
29_T	71_L	0.906	0.94
286_V	296_G	0.905	0.94
155_Y	159_D	0.904	0.94
104_L	109_Y	0.903	0.94
103_A	337_L	0.901	0.94
409_F	413_G	0.897	0.94
157_I	217_A	0.896	0.94
58_L	319_R	0.895	0.94
52_L	341_L	0.893	0.94
56_A	334_D	0.890	0.94
376_V	491_V	0.890	0.94
354_K	431_F	0.889	0.94
179_V	224_A	0.889	0.94
384_K	538_L	0.889	0.94
413_G	440_Y	0.889	0.94
301_Q	312_T	0.889	0.94
277_K	281_N	0.888	0.94
389_H	540_A	0.885	0.94
176_Y	221_V	0.884	0.94
59_I	107_L	0.883	0.94
572_A	576_A	0.883	0.94
58_L	62_A	0.882	0.94
150_P	208_Y	0.881	0.94
409_F	412_G	0.879	0.93
492_I	495_V	0.873	0.93
442_N	542_N	0.873	0.93
227_G	258_A	0.873	0.93
61_D	331_A	0.871	0.93
26_I	70_V	0.865	0.93
406_A	495_V	0.864	0.93
412_G	440_Y	0.864	0.93
346_D	350_Q	0.860	0.93
160_T	176_Y	0.860	0.93
448_K	559_I	0.859	0.93
32_L	100_V	0.858	0.93
413_G	442_N	0.856	0.93
311_V	314_A	0.856	0.93
453_E	553_G	0.856	0.93
104_L	135_F	0.854	0.92
76_D	117_H	0.853	0.92
503_Q	518_A	0.851	0.92
553_G	556_D	0.851	0.92
142_V	180_V	0.851	0.92
548_G	551_F	0.850	0.92
123_L	127_K	0.850	0.92
33_H	227_G	0.847	0.92
208_Y	212_M	0.846	0.92
363_M	374_P	0.845	0.92
61_D	64_N	0.843	0.92
382_A	570_V	0.835	0.92
302_L	311_V	0.833	0.91
573_A	576_A	0.832	0.91
13_I	16_S	0.831	0.91
411_V	487_Y	0.830	0.91
455_K	519_E	0.830	0.91
31_D	259_H	0.828	0.91
451_G	537_F	0.827	0.91
434_A	568_R	0.827	0.91
174_I	221_V	0.826	0.91
54_R	333_E	0.826	0.91
24_L	174_I	0.825	0.91
98_H	102_K	0.824	0.91
53_V	333_E	0.824	0.91
203_E	207_K	0.822	0.91
261_V	294_H	0.821	0.91
159_D	174_I	0.821	0.91
252_A	314_A	0.820	0.91
142_V	196_V	0.819	0.91
177_I	212_M	0.818	0.91
573_A	577_D	0.816	0.91
116_N	225_H	0.815	0.91
24_L	300_L	0.815	0.91
177_I	250_V	0.814	0.91
386_Y	573_A	0.813	0.90
376_V	414_R	0.809	0.90
220_V	249_G	0.807	0.90
187_W	257_H	0.805	0.90
454_V	458_L	0.804	0.90
356_I	572_A	0.804	0.90
73_D	113_T	0.803	0.90
458_L	497_Y	0.802	0.90
504_P	518_A	0.801	0.90
459_E	521_I	0.799	0.90
227_G	257_H	0.798	0.90
337_L	340_T	0.796	0.90
123_L	195_K	0.796	0.90
351_F	354_K	0.794	0.89
406_A	409_F	0.793	0.89
38_D	333_E	0.793	0.89
102_K	344_D	0.791	0.89
403_L	406_A	0.790	0.89
142_V	198_V	0.789	0.89
442_N	543_N	0.789	0.89
406_A	526_F	0.789	0.89
343_A	347_A	0.788	0.89
202_T	206_R	0.788	0.89
383_Q	438_Y	0.788	0.89
61_D	332_A	0.788	0.89
487_Y	490_D	0.788	0.89
360_A	584_E	0.788	0.89
70_V	160_T	0.787	0.89
224_A	255_F	0.786	0.89
25_R	69_S	0.785	0.89
98_H	128_N	0.780	0.89
383_Q	542_N	0.780	0.89
143_I	197_T	0.778	0.88
375_T	437_L	0.775	0.88
449_A	554_T	0.774	0.88
224_A	253_I	0.772	0.88
113_T	223_L	0.771	0.88
155_Y	160_T	0.767	0.88
544_Y	549_G	0.764	0.88
385_A	389_H	0.764	0.88
185_M	198_V	0.763	0.87
29_T	55_T	0.763	0.87
155_Y	158_K	0.762	0.87
114_L	119_F	0.757	0.87
123_L	196_V	0.756	0.87
240_S	255_F	0.756	0.87
454_V	539_V	0.755	0.87
102_K	340_T	0.754	0.87
225_H	259_H	0.752	0.87
503_Q	520_R	0.749	0.86
116_N	259_H	0.748	0.86
33_H	80_G	0.747	0.86
454_V	495_V	0.747	0.86
73_D	104_L	0.746	0.86
117_H	259_H	0.745	0.86
110_T	160_T	0.743	0.86
22_V	166_D	0.742	0.86
205_V	247_I	0.741	0.86
128_N	131_A	0.738	0.86
490_D	497_Y	0.737	0.86
76_D	257_H	0.736	0.86
120_N	184_I	0.735	0.85
188_D	193_S	0.735	0.85
460_C	463_G	0.735	0.85
209_V	213_R	0.735	0.85
212_M	216_G	0.732	0.85
445_I	546_A	0.730	0.85
33_H	225_H	0.730	0.85
199_N	203_E	0.729	0.85
77_L	112_G	0.726	0.85
117_H	257_H	0.726	0.85
55_T	71_L	0.726	0.85
504_P	520_R	0.726	0.85
453_E	456_E	0.724	0.85
193_S	198_V	0.723	0.85
12_L	15_A	0.722	0.84
76_D	259_H	0.722	0.84
461_S	464_Q	0.722	0.84
438_Y	571_L	0.720	0.84
66_V	299_D	0.720	0.84
368_A	373_D	0.719	0.84
55_T	292_G	0.717	0.84
438_Y	567_N	0.717	0.84
380_N	407_A	0.716	0.84
463_G	505_A	0.716	0.84
422_V	436_D	0.716	0.84
374_P	377_Q	0.715	0.84
408_P	539_V	0.715	0.84
458_L	521_I	0.714	0.84
380_N	406_A	0.710	0.83
109_Y	112_G	0.710	0.83
13_I	17_V	0.710	0.83
459_E	504_P	0.707	0.83
74_N	113_T	0.707	0.83
261_V	318_A	0.705	0.83
378_V	382_A	0.704	0.83
381_N	385_A	0.704	0.83
87_M	347_A	0.703	0.83
52_L	103_A	0.699	0.82
68_N	166_D	0.698	0.82
456_E	553_G	0.698	0.82
387_V	540_A	0.697	0.82
128_N	132_G	0.694	0.82
406_A	412_G	0.692	0.82
24_L	172_L	0.692	0.82
280_L	285_A	0.690	0.82
177_I	209_V	0.690	0.82
35_N	81_S	0.689	0.82
499_I	595_L	0.688	0.81
56_A	107_L	0.688	0.81
113_T	139_N	0.688	0.81
14_A	17_V	0.687	0.81
38_D	54_R	0.687	0.81
116_N	120_N	0.686	0.81
205_V	243_Y	0.684	0.81
32_L	77_L	0.683	0.81
125_Y	129_A	0.682	0.81
27_M	71_L	0.681	0.81
149_Q	214_E	0.681	0.81
156_L	176_Y	0.681	0.81
407_A	412_G	0.679	0.81
434_A	572_A	0.678	0.81
140_A	178_G	0.677	0.80
114_L	137_Y	0.673	0.80
181_P	184_I	0.671	0.80
274_D	277_K	0.670	0.80
33_H	79_Q	0.670	0.80
136_P	156_L	0.668	0.80
111_V	223_L	0.668	0.80
244_L	285_A	0.666	0.79
356_I	575_I	0.664	0.79
103_A	341_L	0.664	0.79
204_T	207_K	0.662	0.79
34_S	100_V	0.662	0.79
353_S	432_R	0.660	0.79
63_R	110_T	0.660	0.79
87_M	344_D	0.658	0.79
32_L	109_Y	0.658	0.79
523_N	531_I	0.658	0.79
210_P	248_P	0.657	0.78
494_G	526_F	0.656	0.78
413_G	544_Y	0.652	0.78
383_Q	567_N	0.651	0.78
448_K	558_H	0.649	0.78
62_A	319_R	0.648	0.77
389_H	404_S	0.647	0.77
277_K	283_V	0.647	0.77
77_L	104_L	0.647	0.77
12_L	17_V	0.647	0.77
21_T	312_T	0.646	0.77
15_A	18_N	0.646	0.77
336_K	339_E	0.645	0.77
12_L	18_N	0.645	0.77
460_C	551_F	0.644	0.77
489_F	492_I	0.643	0.77
238_E	241_V	0.641	0.77
361_D	426_K	0.641	0.77
119_F	126_L	0.641	0.77
241_V	245_S	0.639	0.77
377_Q	592_N	0.638	0.76
280_L	283_V	0.637	0.76
254_M	296_G	0.635	0.76
144_D	149_Q	0.633	0.76
146_R	197_T	0.633	0.76
52_L	55_T	0.632	0.76
279_T	282_G	0.631	0.76
524_L	533_P	0.630	0.76
533_P	536_M	0.630	0.76
406_A	537_F	0.629	0.75
212_M	215_K	0.628	0.75
358_K	583_G	0.627	0.75
255_F	287_M	0.627	0.75
458_L	492_I	0.626	0.75
457_W	539_V	0.626	0.75
185_M	196_V	0.626	0.75
33_H	116_N	0.626	0.75
130_L	138_V	0.625	0.75
543_N	567_N	0.625	0.75
219_V	300_L	0.622	0.75
441_P	568_R	0.621	0.74
33_H	76_D	0.621	0.74
188_D	544_Y	0.621	0.74
447_V	541_T	0.620	0.74
240_S	285_A	0.620	0.74
455_K	531_I	0.619	0.74
386_Y	570_V	0.618	0.74
186_G	550_K	0.616	0.74
88_S	121_Y	0.616	0.74
363_M	378_V	0.615	0.74
407_A	542_N	0.613	0.74
179_V	243_Y	0.612	0.73
346_D	349_R	0.612	0.73
316_A	321_I	0.612	0.73
372_D	493_D	0.611	0.73
172_L	302_L	0.611	0.73
114_L	126_L	0.610	0.73
87_M	99_P	0.609	0.73
274_D	282_G	0.608	0.73
505_A	518_A	0.608	0.73
154_P	160_T	0.608	0.73
191_N	194_G	0.607	0.73
571_L	575_I	0.607	0.73
140_A	205_V	0.607	0.73
25_R	65_E	0.607	0.73
30_T	439_L	0.606	0.73
565_D	570_V	0.605	0.73
206_R	247_I	0.605	0.73
454_V	533_P	0.604	0.72
175_G	216_G	0.603	0.72
386_Y	565_D	0.602	0.72
458_L	495_V	0.601	0.72
219_V	311_V	0.601	0.72
408_P	457_W	0.601	0.72
370_V	539_V	0.599	0.72
201_I	204_T	0.598	0.72
410_K	442_N	0.598	0.72
33_H	287_M	0.596	0.71
380_N	409_F	0.595	0.71
79_Q	227_G	0.593	0.71
352_V	432_R	0.592	0.71
460_C	488_N	0.592	0.71
74_N	223_L	0.592	0.71
154_P	157_I	0.592	0.71
377_Q	493_D	0.591	0.71
406_A	494_G	0.589	0.71
32_L	104_L	0.587	0.70
299_D	315_K	0.585	0.70
350_Q	353_S	0.584	0.70
542_N	545_R	0.584	0.70
303_S	306_S	0.584	0.70
33_H	117_H	0.581	0.70
155_Y	215_K	0.579	0.69
89_A	99_P	0.576	0.69
443_T	566_E	0.575	0.69
193_S	196_V	0.575	0.69
63_R	107_L	0.575	0.69
63_R	108_D	0.575	0.69
38_D	50_F	0.575	0.69
238_E	243_Y	0.573	0.68
409_F	567_N	0.573	0.68
409_F	442_N	0.573	0.68
223_L	254_M	0.573	0.68
21_T	303_S	0.573	0.68
134_K	213_R	0.572	0.68
173_K	218_D	0.572	0.68
422_V	425_E	0.571	0.68
425_E	428_Q	0.571	0.68
12_L	19_A	0.570	0.68
541_T	554_T	0.569	0.68
173_K	215_K	0.567	0.68
74_N	259_H	0.567	0.68
248_P	283_V	0.567	0.68
57_S	60_N	0.566	0.68
175_G	208_Y	0.566	0.68
238_E	244_L	0.564	0.67
430_T	433_N	0.563	0.67
531_I	537_F	0.563	0.67
565_D	573_A	0.562	0.67
129_A	133_A	0.562	0.67
228_L	232_P	0.562	0.67
72_V	158_K	0.561	0.67
372_D	590_D	0.560	0.67
357_G	578_E	0.559	0.67
12_L	16_S	0.559	0.67
332_A	335_S	0.558	0.66
183_Q	186_G	0.557	0.66
294_H	320_P	0.556	0.66
179_V	222_V	0.555	0.66
59_I	295_L	0.555	0.66
295_L	319_R	0.554	0.66
460_C	550_K	0.554	0.66
98_H	132_G	0.553	0.66
60_N	64_N	0.552	0.66
30_T	74_N	0.552	0.66
138_V	156_L	0.552	0.66
77_L	109_Y	0.551	0.65
54_R	321_I	0.551	0.65
143_I	148_K	0.551	0.65
496_N	523_N	0.550	0.65
143_I	208_Y	0.549	0.65
237_A	243_Y	0.549	0.65
228_L	240_S	0.548	0.65
79_Q	257_H	0.548	0.65
409_F	438_Y	0.547	0.65
73_D	112_G	0.547	0.65
372_D	592_N	0.546	0.65
434_A	575_I	0.546	0.65
36_M	341_L	0.546	0.65
152_F	253_I	0.546	0.65
384_K	407_A	0.546	0.65
120_N	225_H	0.544	0.64
532_D	536_M	0.544	0.64
239_N	242_Y	0.543	0.64
490_D	493_D	0.543	0.64
24_L	302_L	0.542	0.64
140_A	154_P	0.542	0.64
210_P	217_A	0.542	0.64
410_K	439_L	0.541	0.64
148_K	197_T	0.540	0.64
181_P	287_M	0.539	0.64
382_A	571_L	0.538	0.64
22_V	172_L	0.538	0.64
406_A	411_V	0.538	0.64
230_A	242_Y	0.538	0.64
302_L	306_S	0.538	0.64
84_A	88_S	0.538	0.64
405_A	411_V	0.538	0.64
117_H	440_Y	0.537	0.63
369_L	487_Y	0.536	0.63
424_V	427_G	0.536	0.63
248_P	279_T	0.535	0.63
73_D	80_G	0.534	0.63
575_I	583_G	0.534	0.63
255_F	258_A	0.533	0.63
369_L	411_V	0.533	0.63
227_G	259_H	0.532	0.63
160_T	208_Y	0.532	0.63
414_R	491_V	0.531	0.63
231_D	255_F	0.530	0.62
102_K	343_A	0.530	0.62
114_L	138_V	0.530	0.62
210_P	249_G	0.529	0.62
362_N	425_E	0.527	0.62
588_A	591_N	0.527	0.62
201_I	226_S	0.527	0.62
389_H	577_D	0.527	0.62
404_S	409_F	0.526	0.62
372_D	591_N	0.526	0.62
239_N	244_L	0.525	0.62
173_K	216_G	0.525	0.62
18_N	21_T	0.524	0.62
84_A	89_A	0.523	0.61
54_R	331_A	0.523	0.61
184_I	187_W	0.523	0.61
386_Y	444_L	0.522	0.61
259_H	290_M	0.522	0.61
29_T	32_L	0.522	0.61
85_D	441_P	0.521	0.61
444_L	570_V	0.521	0.61
560_A	563_S	0.521	0.61
78_I	118_E	0.520	0.61
423_E	426_K	0.520	0.61
376_V	380_N	0.520	0.61
365_S	373_D	0.519	0.61
80_G	227_G	0.518	0.61
184_I	188_D	0.518	0.61
79_Q	118_E	0.517	0.61
20_A	304_N	0.517	0.61
24_L	251_N	0.517	0.61
157_I	175_G	0.516	0.60
552_A	555_G	0.514	0.60
245_S	281_N	0.511	0.60
35_N	80_G	0.511	0.60
255_F	285_A	0.511	0.60
74_N	288_P	0.511	0.60
63_R	66_V	0.511	0.60
413_G	542_N	0.510	0.60
102_K	106_T	0.510	0.60
63_R	69_S	0.509	0.59
236_M	241_V	0.508	0.59
102_K	337_L	0.506	0.59
408_P	411_V	0.505	0.59
112_G	133_A	0.504	0.59
228_L	262_F	0.504	0.59
107_L	198_V	0.503	0.59
31_D	257_H	0.503	0.59
407_A	540_A	0.502	0.58
182_P	226_S	0.502	0.58
144_D	148_K	0.502	0.58
72_V	221_V	0.501	0.58
110_T	158_K	0.501	0.58
185_M	193_S	0.501	0.58
202_T	247_I	0.500	0.58

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2z1aA	1	0.7573	100	0.322	Contact Map
4h2gA	2	0.7651	100	0.342	Contact Map
3ztvA	2	0.7682	100	0.347	Contact Map
4q7fA	1	0.7666	100	0.348	Contact Map
3iveA	1	0.7434	100	0.351	Contact Map
1hp1A	1	0.7635	100	0.369	Contact Map
2wdcA	1	0.7527	100	0.383	Contact Map
3c9fA	2	0.7697	100	0.513	Contact Map
3jyfA	2	0.5193	100	0.576	Contact Map
3gveA	2	0.5085	100	0.585	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0143 seconds.