ARAB - ECOLI - GREMLIN Contacts

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ARAB - Ribulokinase

UniProt:	P08204	Sequences: MAIAIGLDFGSDSVRALAVDCATGEEIATSVEWYPRWQKGQFCDAPNNQFRHHPRDYIESMEAALKTVLAELSVEQRAAVVGIGVDSTGSTPAPIDADGNVLALRPEFAENPNAMFVLWKDHTAVEEAEEITRLCHAPGNVDYSRYIGGIYSSEWFWAKILHVTRQDSAVAQSAASWIELCDWVPALLSGTTRPQDIRRGRCSAGHKSLWHESWGGLPPASFFDELDPILNRHLPSPLFTDTWTADIPVGTLCPEWAQRLGLPESVVISGGAFDCHMGAVGAGAQPNALVKVIGTSTCDILIADKQSVGERAVKGICGQVDGSVVPGFIGLEAGQSAFGDIYAWFGRVLGWPLEQLAAQHPELKTQINASQKQLLPALTEAWAKNPSLDHLPVVLDWFNGRRTPNANQRLKGVITDLNLATDAPLLFGGLIAATAFGARAIMECFTDQGIAVNNVMALGGIARKNQVIMQACCDVLNRPLQIVASDQCCALGAAIFAAVAAKVHADIPSAQQKMASAVEKTLQPCSEQAQRFEQLYRRYQQWAMSAEQHYLPTSAPAQAAQAVATL	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10053
Length:	566 (479)
Sequences:	11865 (8046)
Seq/√Len:	367.6

ECOLI - ARAB LYXK LSRK XYLB GLPK RHAB FUCK YGCE
BACSU - ARAB XYLB GNTK GLPK YOAC RHAB
HALSA - GLPK
SULSO - GLPK1 GLPK2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
220_A	236_S	4.357	1.00
127_E	165_R	3.914	1.00
20_D	25_E	3.634	1.00
16_A	64_A	3.330	1.00
130_E	165_R	3.266	1.00
20_D	23_T	3.192	1.00
439_R	536_Y	2.940	1.00
479_P	523_Q	2.927	1.00
211_H	214_W	2.870	1.00
146_Y	219_P	2.862	1.00
102_L	170_V	2.854	1.00
439_R	443_E	2.815	1.00
506_D	509_S	2.772	1.00
470_Q	474_D	2.751	1.00
414_I	426_L	2.746	1.00
446_T	478_R	2.746	1.00
32_E	63_A	2.727	1.00
32_E	67_T	2.725	1.00
210_W	242_T	2.672	1.00
37_W	115_M	2.670	1.00
505_A	509_S	2.626	1.00
30_S	67_T	2.621	1.00
466_Q	520_K	2.620	1.00
454_N	481_Q	2.613	1.00
96_D	173_S	2.541	1.00
244_T	247_I	2.504	1.00
18_A	68_V	2.502	1.00
216_G	236_S	2.471	1.00
55_R	187_L	2.462	1.00
58_I	187_L	2.392	1.00
211_H	219_P	2.380	1.00
439_R	533_E	2.370	1.00
223_F	236_S	2.358	1.00
114_A	167_D	2.328	1.00
97_A	175_A	2.327	1.00
385_N	425_L	2.296	1.00
185_P	271_G	2.241	1.00
75_E	78_A	2.222	1.00
191_T	241_D	2.222	1.00
220_A	224_D	2.192	1.00
272_A	277_M	2.126	1.00
390_H	425_L	2.121	1.00
13_S	31_V	2.094	1.00
7_L	61_M	2.089	1.00
341_I	430_L	2.080	1.00
130_E	134_L	2.054	1.00
55_R	100_N	2.044	1.00
17_L	490_A	2.013	1.00
394_V	414_I	2.007	1.00
525_C	528_Q	1.974	1.00
67_T	71_E	1.968	1.00
297_T	338_F	1.965	1.00
46_P	49_Q	1.952	1.00
393_V	538_R	1.951	1.00
253_C	256_W	1.941	1.00
142_D	145_R	1.936	1.00
477_N	529_A	1.925	1.00
35_P	56_D	1.887	1.00
4_A	498_A	1.875	1.00
446_T	451_A	1.857	1.00
161_L	165_R	1.844	1.00
5_I	65_L	1.843	1.00
189_S	268_I	1.835	1.00
9_F	14_V	1.834	1.00
474_D	525_C	1.816	1.00
536_Y	540_Q	1.803	1.00
254_P	264_E	1.792	1.00
457_A	469_M	1.787	1.00
176_S	192_T	1.780	1.00
481_Q	521_T	1.780	1.00
5_I	16_A	1.761	1.00
3_I	27_I	1.753	1.00
269_S	500_A	1.752	1.00
93_A	181_C	1.741	1.00
146_Y	221_S	1.740	1.00
422_D	425_L	1.729	1.00
198_R	243_W	1.721	1.00
142_D	146_Y	1.705	1.00
345_F	430_L	1.702	1.00
94_P	163_V	1.690	1.00
99_G	186_A	1.687	1.00
474_D	528_Q	1.656	1.00
129_E	133_R	1.652	1.00
479_P	521_T	1.649	1.00
248_P	251_T	1.640	1.00
243_W	247_I	1.639	1.00
436_F	535_L	1.632	1.00
142_D	221_S	1.629	1.00
132_T	140_N	1.619	1.00
374_L	377_A	1.600	1.00
96_D	100_N	1.592	1.00
94_P	238_L	1.568	1.00
288_A	454_N	1.556	1.00
443_E	540_Q	1.541	1.00
126_E	130_E	1.540	1.00
3_I	18_A	1.534	1.00
529_A	533_E	1.533	1.00
248_P	269_S	1.532	1.00
4_A	503_V	1.529	1.00
541_Q	545_S	1.525	1.00
380_E	384_K	1.524	1.00
343_A	347_R	1.512	1.00
411_K	418_N	1.506	1.00
443_E	446_T	1.501	1.00
527_E	530_Q	1.501	1.00
37_W	56_D	1.497	1.00
382_W	385_N	1.482	1.00
53_H	56_D	1.461	1.00
141_V	145_R	1.457	1.00
467_V	471_A	1.444	1.00
286_P	304_D	1.443	1.00
82_G	497_A	1.440	1.00
189_S	250_G	1.440	1.00
30_S	68_V	1.438	1.00
377_A	380_E	1.435	1.00
263_P	266_V	1.433	1.00
484_A	519_E	1.430	1.00
30_S	64_A	1.414	1.00
169_A	172_Q	1.396	1.00
185_P	249_V	1.392	1.00
55_R	59_E	1.389	1.00
251_T	265_S	1.379	1.00
466_Q	482_I	1.378	1.00
498_A	504_H	1.373	1.00
428_G	432_A	1.370	1.00
466_Q	522_L	1.365	1.00
381_A	384_K	1.365	1.00
28_A	71_E	1.354	1.00
28_A	68_V	1.352	1.00
97_A	177_W	1.352	1.00
353_L	377_A	1.339	1.00
68_V	72_L	1.337	1.00
293_I	472_C	1.336	1.00
185_P	198_R	1.335	1.00
183_W	187_L	1.334	1.00
394_V	398_F	1.332	1.00
125_V	129_E	1.323	1.00
394_V	430_L	1.311	1.00
243_W	249_V	1.308	1.00
75_E	79_A	1.301	1.00
435_A	475_V	1.298	1.00
7_L	65_L	1.293	1.00
14_V	61_M	1.292	1.00
235_P	238_L	1.291	1.00
162_H	166_Q	1.290	1.00
22_A	503_V	1.288	1.00
335_Q	437_G	1.282	1.00
142_D	225_E	1.272	1.00
89_G	273_F	1.270	1.00
58_I	62_E	1.266	1.00
454_N	479_P	1.265	1.00
482_I	522_L	1.264	1.00
289_L	452_V	1.259	1.00
435_A	471_A	1.257	1.00
378_L	427_F	1.250	1.00
127_E	161_L	1.239	1.00
18_A	74_V	1.236	1.00
223_F	239_F	1.235	1.00
14_V	60_S	1.232	1.00
464_K	486_D	1.230	1.00
287_N	453_N	1.228	1.00
291_K	472_C	1.227	1.00
435_A	472_C	1.224	1.00
377_A	381_A	1.224	1.00
471_A	475_V	1.212	1.00
469_M	522_L	1.211	1.00
384_K	424_P	1.211	1.00
191_T	198_R	1.207	1.00
382_W	467_V	1.202	1.00
91_T	116_F	1.200	1.00
443_E	536_Y	1.199	1.00
530_Q	534_Q	1.193	1.00
272_A	496_F	1.188	1.00
285_Q	511_Q	1.186	1.00
157_W	226_L	1.184	1.00
128_A	151_Y	1.178	1.00
413_V	546_A	1.172	1.00
375_L	378_L	1.168	1.00
164_T	171_A	1.166	1.00
201_R	215_G	1.162	1.00
69_L	76_Q	1.160	1.00
381_A	424_P	1.157	1.00
440_A	540_Q	1.157	1.00
143_Y	151_Y	1.153	1.00
19_V	26_E	1.152	1.00
61_M	184_V	1.141	1.00
392_P	421_T	1.137	1.00
7_L	16_A	1.136	1.00
385_N	424_P	1.135	1.00
477_N	533_E	1.132	1.00
337_A	341_I	1.132	1.00
134_L	225_E	1.129	1.00
59_E	63_A	1.129	1.00
528_Q	531_R	1.127	1.00
417_L	421_T	1.126	1.00
248_P	267_V	1.119	1.00
341_I	394_V	1.118	1.00
51_R	115_M	1.117	1.00
63_A	67_T	1.117	1.00
221_S	224_D	1.117	1.00
169_A	173_S	1.115	1.00
248_P	500_A	1.109	1.00
439_R	476_L	1.106	1.00
285_Q	288_A	1.106	1.00
349_L	426_L	1.105	1.00
201_R	242_T	1.103	1.00
312_A	316_I	1.103	1.00
3_I	74_V	1.102	1.00
28_A	72_L	1.090	1.00
54_P	93_A	1.086	1.00
415_T	542_W	1.085	1.00
442_M	476_L	1.083	1.00
171_A	174_A	1.081	1.00
167_D	170_V	1.077	1.00
288_A	456_M	1.074	1.00
82_G	501_A	1.074	1.00
533_E	537_R	1.069	1.00
126_E	129_E	1.067	1.00
34_Y	60_S	1.066	1.00
18_A	72_L	1.064	1.00
381_A	423_A	1.063	1.00
30_S	71_E	1.059	1.00
3_I	79_A	1.058	1.00
95_I	178_I	1.056	1.00
36_R	52_H	1.050	1.00
434_T	461_I	1.050	1.00
285_Q	508_P	1.048	1.00
53_H	115_M	1.041	1.00
174_A	238_L	1.039	1.00
305_K	326_P	1.034	1.00
50_F	120_K	1.031	1.00
94_P	174_A	1.029	1.00
337_A	340_D	1.028	1.00
379_T	465_N	1.025	1.00
210_W	214_W	1.023	1.00
4_A	501_A	1.023	1.00
456_M	481_Q	1.023	1.00
127_E	166_Q	1.022	1.00
421_T	425_L	1.022	1.00
19_V	494_A	1.021	1.00
99_G	192_T	1.019	1.00
85_V	185_P	1.019	1.00
380_E	383_A	1.015	1.00
198_R	249_V	1.015	1.00
67_T	70_A	1.015	1.00
201_R	210_W	1.014	1.00
182_D	199_R	1.012	1.00
499_V	510_A	1.010	1.00
127_E	130_E	1.005	1.00
412_G	417_L	1.001	1.00
61_M	65_L	1.001	1.00
538_R	541_Q	0.996	1.00
379_T	383_A	0.990	1.00
94_P	160_I	0.988	1.00
518_V	521_T	0.987	1.00
484_A	515_A	0.986	1.00
56_D	59_E	0.986	1.00
129_E	132_T	0.981	1.00
285_Q	512_Q	0.981	1.00
509_S	512_Q	0.981	1.00
525_C	529_A	0.975	1.00
82_G	269_S	0.972	1.00
504_H	510_A	0.971	1.00
289_L	301_L	0.970	1.00
170_V	173_S	0.966	1.00
376_P	379_T	0.965	1.00
436_F	475_V	0.964	1.00
428_G	467_V	0.959	1.00
201_R	323_S	0.957	1.00
69_L	80_V	0.957	1.00
62_E	66_K	0.957	1.00
74_V	79_A	0.955	1.00
495_I	510_A	0.955	1.00
16_A	68_V	0.952	1.00
143_Y	208_S	0.952	1.00
223_F	234_L	0.949	1.00
157_W	208_S	0.945	1.00
179_E	182_D	0.944	1.00
269_S	501_A	0.941	1.00
436_F	536_Y	0.940	1.00
461_I	468_I	0.940	1.00
69_L	72_L	0.939	1.00
81_V	501_A	0.934	1.00
66_K	70_A	0.934	1.00
439_R	475_V	0.932	1.00
394_V	429_G	0.928	1.00
100_N	187_L	0.927	1.00
454_N	521_T	0.920	1.00
498_A	503_V	0.914	1.00
477_N	531_R	0.908	1.00
163_V	170_V	0.903	1.00
251_T	267_V	0.901	1.00
130_E	133_R	0.894	1.00
417_L	426_L	0.891	1.00
285_Q	453_N	0.890	1.00
20_D	27_I	0.889	1.00
83_I	266_V	0.889	1.00
215_G	244_T	0.889	1.00
130_E	161_L	0.888	1.00
476_L	479_P	0.887	1.00
32_E	64_A	0.887	1.00
84_G	269_S	0.885	1.00
39_K	47_N	0.884	1.00
145_R	311_R	0.884	1.00
299_D	442_M	0.882	1.00
198_R	241_D	0.871	1.00
136_H	225_E	0.869	1.00
168_S	172_Q	0.868	1.00
5_I	18_A	0.867	1.00
86_D	489_C	0.865	1.00
256_W	260_L	0.864	1.00
495_I	514_M	0.860	1.00
290_V	458_L	0.859	1.00
92_P	178_I	0.857	1.00
18_A	80_V	0.856	1.00
145_R	213_S	0.855	1.00
323_S	327_G	0.853	1.00
526_S	529_A	0.853	1.00
175_A	237_P	0.847	1.00
252_L	262_L	0.847	1.00
443_E	447_D	0.846	1.00
202_C	322_G	0.845	1.00
179_E	207_K	0.843	1.00
9_F	184_V	0.842	1.00
122_H	152_S	0.842	1.00
157_W	209_L	0.840	1.00
289_L	455_V	0.839	1.00
382_W	386_P	0.838	1.00
470_Q	525_C	0.836	1.00
199_R	204_A	0.836	1.00
90_S	206_H	0.833	1.00
391_L	535_L	0.830	1.00
407_N	410_L	0.826	1.00
382_W	427_F	0.823	1.00
297_T	438_A	0.822	1.00
415_T	546_A	0.819	1.00
216_G	241_D	0.817	1.00
5_I	80_V	0.812	1.00
57_Y	180_L	0.810	1.00
414_I	430_L	0.810	1.00
96_D	102_L	0.810	1.00
302_I	328_F	0.809	1.00
128_A	158_A	0.807	1.00
114_A	163_V	0.805	1.00
278_G	458_L	0.804	1.00
455_V	476_L	0.804	1.00
431_I	471_A	0.802	1.00
251_T	264_E	0.800	1.00
393_V	415_T	0.800	1.00
161_L	227_D	0.799	1.00
462_A	486_D	0.799	1.00
526_S	531_R	0.799	1.00
304_D	328_F	0.798	1.00
102_L	173_S	0.798	1.00
254_P	265_S	0.798	1.00
19_V	491_L	0.798	1.00
128_A	153_S	0.797	1.00
216_G	220_A	0.797	1.00
33_W	343_A	0.796	1.00
190_G	253_C	0.795	1.00
161_L	164_T	0.794	1.00
526_S	530_Q	0.793	1.00
499_V	507_I	0.791	1.00
350_G	423_A	0.791	1.00
210_W	215_G	0.791	1.00
123_T	162_H	0.790	1.00
94_P	177_W	0.786	1.00
353_L	423_A	0.783	1.00
344_W	347_R	0.780	1.00
388_L	391_L	0.780	1.00
204_A	218_P	0.779	1.00
252_L	260_L	0.778	1.00
481_Q	518_V	0.778	1.00
78_A	263_P	0.776	1.00
132_T	151_Y	0.776	1.00
199_R	240_T	0.774	1.00
160_I	209_L	0.772	1.00
89_G	332_E	0.772	1.00
541_Q	544_M	0.771	1.00
65_L	69_L	0.770	1.00
178_I	192_T	0.769	1.00
243_W	270_G	0.769	1.00
54_P	115_M	0.768	1.00
510_A	514_M	0.768	1.00
126_E	166_Q	0.767	1.00
136_H	142_D	0.766	1.00
201_R	244_T	0.765	1.00
275_C	298_C	0.763	1.00
80_V	266_V	0.763	1.00
186_A	192_T	0.762	1.00
33_W	346_G	0.762	1.00
178_I	182_D	0.762	1.00
298_C	334_G	0.760	1.00
89_G	203_S	0.758	1.00
177_W	238_L	0.758	1.00
342_Y	379_T	0.757	1.00
345_F	427_F	0.756	1.00
19_V	485_S	0.755	1.00
146_Y	211_H	0.755	1.00
23_T	513_K	0.754	1.00
9_F	61_M	0.751	1.00
81_V	503_V	0.751	1.00
4_A	82_G	0.749	1.00
442_M	446_T	0.748	1.00
62_E	256_W	0.748	1.00
376_P	380_E	0.746	1.00
466_Q	470_Q	0.744	1.00
435_A	468_I	0.743	1.00
95_I	99_G	0.743	1.00
85_V	188_L	0.741	1.00
129_E	409_R	0.739	1.00
410_L	413_V	0.738	1.00
470_Q	522_L	0.736	1.00
439_R	540_Q	0.734	1.00
34_Y	52_H	0.732	1.00
431_I	465_N	0.730	1.00
282_A	458_L	0.730	1.00
32_E	60_S	0.728	1.00
56_D	60_S	0.728	1.00
333_A	441_I	0.727	1.00
465_N	468_I	0.727	1.00
530_Q	535_L	0.727	1.00
457_A	472_C	0.723	1.00
457_A	482_I	0.721	1.00
535_L	538_R	0.721	1.00
440_A	536_Y	0.721	1.00
85_V	184_V	0.721	1.00
534_Q	537_R	0.717	1.00
221_S	225_E	0.717	1.00
291_K	438_A	0.716	1.00
215_G	323_S	0.716	1.00
534_Q	538_R	0.715	1.00
6_G	84_G	0.714	0.99
119_W	296_S	0.713	0.99
401_R	404_P	0.712	0.99
226_L	234_L	0.711	0.99
312_A	317_C	0.710	0.99
462_A	469_M	0.709	0.99
291_K	297_T	0.708	0.99
353_L	374_L	0.706	0.99
252_L	266_V	0.706	0.99
457_A	480_L	0.706	0.99
346_G	375_L	0.705	0.99
338_F	434_T	0.705	0.99
301_L	445_F	0.703	0.99
95_I	183_W	0.699	0.99
199_R	242_T	0.698	0.99
219_P	222_F	0.698	0.99
379_T	466_Q	0.696	0.99
126_E	165_R	0.696	0.99
278_G	489_C	0.694	0.99
381_A	385_N	0.691	0.99
173_S	176_S	0.691	0.99
224_D	236_S	0.691	0.99
282_A	290_V	0.689	0.99
55_R	183_W	0.689	0.99
509_S	513_K	0.686	0.99
11_S	118_L	0.685	0.99
39_K	49_Q	0.682	0.99
9_F	60_S	0.681	0.99
172_Q	176_S	0.681	0.99
528_Q	533_E	0.680	0.99
211_H	216_G	0.680	0.99
14_V	34_Y	0.679	0.99
143_Y	222_F	0.679	0.99
83_I	252_L	0.679	0.99
114_A	170_V	0.679	0.99
383_A	467_V	0.678	0.99
262_L	265_S	0.676	0.99
345_F	349_L	0.676	0.99
161_L	171_A	0.674	0.99
99_G	175_A	0.674	0.99
498_A	502_K	0.674	0.99
61_M	64_A	0.671	0.99
540_Q	544_M	0.670	0.99
453_N	478_R	0.668	0.99
508_P	511_Q	0.668	0.99
39_K	46_P	0.667	0.99
479_P	524_P	0.666	0.99
389_D	393_V	0.666	0.99
59_E	62_E	0.664	0.99
181_C	203_S	0.662	0.99
55_R	101_V	0.659	0.99
96_D	175_A	0.659	0.99
248_P	501_A	0.659	0.99
345_F	426_L	0.658	0.99
314_K	447_D	0.657	0.99
94_P	102_L	0.657	0.99
264_E	267_V	0.656	0.99
62_E	187_L	0.656	0.99
4_A	81_V	0.654	0.99
58_I	256_W	0.653	0.99
97_A	173_S	0.652	0.99
147_I	222_F	0.652	0.99
244_T	323_S	0.652	0.99
391_L	428_G	0.649	0.99
495_I	513_K	0.648	0.99
185_P	189_S	0.647	0.99
447_D	540_Q	0.647	0.99
252_L	263_P	0.646	0.99
51_R	123_T	0.646	0.99
245_A	271_G	0.645	0.99
499_V	506_D	0.644	0.99
511_Q	515_A	0.643	0.99
87_S	180_L	0.642	0.99
69_L	74_V	0.642	0.99
397_W	401_R	0.640	0.99
101_V	115_M	0.637	0.99
504_H	513_K	0.636	0.99
192_T	253_C	0.635	0.99
390_H	421_T	0.634	0.99
284_A	288_A	0.634	0.99
215_G	327_G	0.634	0.99
455_V	480_L	0.633	0.99
383_A	386_P	0.632	0.99
227_D	235_P	0.632	0.99
213_S	311_R	0.631	0.99
249_V	270_G	0.631	0.99
93_A	116_F	0.630	0.99
410_L	414_I	0.629	0.99
385_N	390_H	0.628	0.99
533_E	536_Y	0.628	0.99
29_T	487_Q	0.625	0.99
29_T	71_E	0.625	0.99
160_I	238_L	0.624	0.99
234_L	239_F	0.623	0.99
91_T	118_L	0.623	0.99
283_G	511_Q	0.622	0.99
385_N	389_D	0.622	0.99
379_T	382_W	0.621	0.99
22_A	81_V	0.618	0.99
149_G	155_W	0.617	0.99
510_A	513_K	0.617	0.99
256_W	265_S	0.616	0.99
395_L	413_V	0.615	0.99
389_D	425_L	0.612	0.98
65_L	68_V	0.612	0.98
291_K	455_V	0.610	0.98
343_A	375_L	0.609	0.98
387_S	428_G	0.608	0.98
387_S	531_R	0.607	0.98
26_E	29_T	0.606	0.98
88_T	119_W	0.606	0.98
117_V	123_T	0.604	0.98
455_V	478_R	0.604	0.98
482_I	519_E	0.604	0.98
499_V	504_H	0.604	0.98
131_I	226_L	0.602	0.98
432_A	471_A	0.602	0.98
382_W	424_P	0.602	0.98
83_I	268_I	0.601	0.98
284_A	290_V	0.601	0.98
262_L	266_V	0.600	0.98
87_S	203_S	0.599	0.98
241_D	247_I	0.599	0.98
381_A	427_F	0.599	0.98
62_E	260_L	0.598	0.98
386_P	390_H	0.597	0.98
518_V	524_P	0.597	0.98
411_K	414_I	0.596	0.98
274_D	295_T	0.596	0.98
95_I	176_S	0.595	0.98
335_Q	441_I	0.595	0.98
19_V	490_A	0.594	0.98
514_M	518_V	0.592	0.98
288_A	511_Q	0.591	0.98
378_L	382_W	0.591	0.98
348_V	422_D	0.591	0.98
82_G	267_V	0.591	0.98
388_L	425_L	0.591	0.98
95_I	186_A	0.590	0.98
530_Q	533_E	0.589	0.98
136_H	141_V	0.589	0.98
92_P	156_F	0.588	0.98
386_P	389_D	0.588	0.98
315_G	332_E	0.587	0.98
395_L	401_R	0.585	0.98
209_L	239_F	0.585	0.98
183_W	186_A	0.584	0.98
511_Q	514_M	0.584	0.98
50_F	118_L	0.583	0.98
428_G	471_A	0.583	0.98
523_Q	526_S	0.583	0.98
390_H	420_A	0.582	0.98
386_P	425_L	0.581	0.98
273_F	276_H	0.580	0.98
499_V	502_K	0.580	0.98
65_L	260_L	0.580	0.98
388_L	428_G	0.580	0.98
394_V	433_A	0.579	0.98
171_A	227_D	0.579	0.98
161_L	226_L	0.579	0.98
73_S	76_Q	0.579	0.98
507_I	511_Q	0.578	0.98
531_R	535_L	0.578	0.98
281_G	488_C	0.577	0.98
391_L	425_L	0.577	0.98
141_V	144_S	0.576	0.98
143_Y	226_L	0.576	0.98
63_A	66_K	0.574	0.98
477_N	526_S	0.574	0.98
251_T	254_P	0.573	0.98
444_C	447_D	0.572	0.98
293_I	457_A	0.572	0.98
297_T	472_C	0.571	0.98
49_Q	123_T	0.571	0.98
202_C	272_A	0.571	0.98
405_N	440_A	0.570	0.98
508_P	512_Q	0.570	0.98
135_C	222_F	0.568	0.98
283_G	514_M	0.567	0.97
4_A	504_H	0.566	0.97
405_N	540_Q	0.565	0.97
454_N	478_R	0.564	0.97
300_I	330_G	0.563	0.97
303_A	331_L	0.563	0.97
174_A	177_W	0.560	0.97
351_W	423_A	0.559	0.97
38_Q	50_F	0.556	0.97
39_K	115_M	0.556	0.97
51_R	114_A	0.553	0.97
131_I	158_A	0.552	0.97
301_L	452_V	0.552	0.97
434_T	468_I	0.552	0.97
275_C	292_V	0.552	0.97
99_G	176_S	0.552	0.97
436_F	538_R	0.551	0.97
473_C	480_L	0.550	0.97
452_V	478_R	0.550	0.97
260_L	266_V	0.549	0.97
135_C	140_N	0.549	0.97
537_R	540_Q	0.548	0.97
178_I	186_A	0.548	0.97
224_D	227_D	0.548	0.97
280_V	495_I	0.547	0.97
403_T	406_A	0.547	0.97
495_I	499_V	0.547	0.97
124_A	158_A	0.546	0.97
55_R	115_M	0.546	0.97
393_V	436_F	0.545	0.97
405_N	543_A	0.545	0.97
506_D	512_Q	0.544	0.97
54_P	116_F	0.544	0.97
485_S	491_L	0.544	0.97
147_I	208_S	0.544	0.97
62_E	65_L	0.542	0.97
26_E	485_S	0.542	0.97
202_C	245_A	0.541	0.97
25_E	484_A	0.541	0.97
313_V	317_C	0.541	0.97
177_W	186_A	0.540	0.97
202_C	276_H	0.540	0.97
267_V	501_A	0.540	0.97
279_A	300_I	0.539	0.97
379_T	431_I	0.538	0.97
395_L	542_W	0.536	0.96
291_K	299_D	0.535	0.96
246_D	500_A	0.532	0.96
190_G	255_E	0.532	0.96
11_S	119_W	0.532	0.96
171_A	175_A	0.532	0.96
17_L	26_E	0.531	0.96
389_D	428_G	0.530	0.96
191_T	243_W	0.530	0.96
155_W	206_H	0.529	0.96
313_V	316_I	0.528	0.96
72_L	76_Q	0.527	0.96
382_W	428_G	0.527	0.96
378_L	467_V	0.527	0.96
151_Y	208_S	0.527	0.96
213_S	306_Q	0.527	0.96
49_Q	117_V	0.526	0.96
89_G	206_H	0.526	0.96
91_T	180_L	0.525	0.96
252_L	256_W	0.525	0.96
299_D	441_I	0.525	0.96
399_N	419_L	0.524	0.96
55_R	58_I	0.522	0.96
471_A	535_L	0.522	0.96
52_H	118_L	0.522	0.96
153_S	408_Q	0.522	0.96
391_L	538_R	0.522	0.96
297_T	335_Q	0.520	0.96
490_A	493_A	0.519	0.96
484_A	518_V	0.518	0.96
469_M	482_I	0.518	0.96
222_F	226_L	0.518	0.96
185_P	268_I	0.518	0.96
279_A	321_D	0.518	0.96
392_P	426_L	0.517	0.96
222_F	225_E	0.517	0.96
401_R	407_N	0.516	0.96
95_I	175_A	0.516	0.96
245_A	272_A	0.515	0.96
292_V	458_L	0.515	0.96
95_I	192_T	0.515	0.96
319_Q	330_G	0.513	0.95
405_N	410_L	0.512	0.95
134_L	161_L	0.512	0.95
123_T	166_Q	0.512	0.95
182_D	240_T	0.511	0.95
100_N	173_S	0.511	0.95
90_S	119_W	0.510	0.95
60_S	63_A	0.509	0.95
12_D	15_R	0.509	0.95
533_E	540_Q	0.508	0.95
392_P	429_G	0.507	0.95
379_T	467_V	0.506	0.95
125_V	153_S	0.506	0.95
432_A	436_F	0.503	0.95
472_C	476_L	0.503	0.95
213_S	216_G	0.502	0.95
295_T	460_G	0.501	0.95
438_A	472_C	0.501	0.95
76_Q	80_V	0.501	0.95
132_T	136_H	0.500	0.95
335_Q	438_A	0.500	0.95
57_Y	181_C	0.500	0.95

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3ll3A	2	0.8657	100	0.166	Contact Map
3qdkA	2	0.9488	100	0.168	Contact Map
3hz6A	1	0.8516	100	0.186	Contact Map
3ifrA	2	0.8604	100	0.187	Contact Map
2itmA	2	0.8375	100	0.189	Contact Map
3wxlA	2	0.864	100	0.199	Contact Map
3l0qA	2	0.9011	100	0.201	Contact Map
3ezwA	3	0.8604	100	0.203	Contact Map
2d4wA	2	0.8622	100	0.21	Contact Map
3h3nX	3	0.864	100	0.21	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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