GREMLIN Database
FIMG - Protein FimG
UniProt: P08190 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG10314
Length: 167 (158)
Sequences: 3364 (2650)
Seq/√Len: 210.8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
60_S63_A3.1031.00
105_Q152_T2.9371.00
109_L142_V2.9021.00
97_Y108_Q2.8411.00
110_E143_R2.8171.00
112_Q143_R2.6721.00
71_A137_H2.5971.00
110_E145_L2.5811.00
40_T76_N2.5801.00
84_V164_Y2.5121.00
100_N156_I2.5021.00
144_A156_I2.4851.00
98_Y121_T2.4321.00
42_S75_T2.3551.00
116_G141_Q2.3041.00
73_E137_H2.1121.00
113_D117_N2.0621.00
109_L158_A2.0431.00
59_M63_A2.0051.00
106_N151_A2.0051.00
103_T155_T1.9881.00
71_A139_P1.9451.00
93_D147_V1.8481.00
98_Y160_I1.8261.00
120_N123_A1.7941.00
18_S22_Q1.7721.00
110_E118_T1.7551.00
97_Y145_L1.7381.00
67_W143_R1.7321.00
64_A110_E1.6831.00
42_S73_E1.6691.00
69_D141_Q1.5701.00
43_T46_A1.5231.00
89_S122_G1.5141.00
96_G120_N1.5061.00
89_S163_T1.4741.00
51_G68_H1.4691.00
92_A96_G1.4571.00
53_L65_S1.4321.00
97_Y110_E1.4231.00
131_D134_Q1.4211.00
60_S146_T1.4051.00
69_D139_P1.3501.00
70_V111_L1.3421.00
58_L146_T1.3401.00
90_G93_D1.3371.00
51_G156_I1.3281.00
51_G66_A1.3251.00
16_L19_A1.2941.00
15_A19_A1.2931.00
90_G98_Y1.2841.00
12_A15_A1.2811.00
33_K52_D1.2731.00
46_A72_L1.2691.00
43_T73_E1.2621.00
50_L144_A1.2511.00
11_A14_L1.2461.00
64_A143_R1.1861.00
85_T165_T1.1581.00
87_S124_T1.1541.00
59_M146_T1.1501.00
84_V136_A1.1401.00
50_L109_L1.1051.00
13_I16_L1.1031.00
146_T151_A1.1001.00
86_A138_F1.0871.00
67_W141_Q1.0801.00
64_A112_Q1.0671.00
48_V70_V1.0601.00
58_L147_V1.0571.00
146_T150_G1.0491.00
29_T159_V1.0461.00
64_A145_L1.0451.00
21_I24_A1.0391.00
58_L107_I1.0381.00
40_T75_T1.0341.00
58_L151_A1.0241.00
106_N149_G1.0121.00
50_L156_I0.9881.00
54_Y57_S0.9861.00
14_L18_S0.9851.00
26_V162_I0.9741.00
131_D136_A0.9681.00
102_G155_T0.9641.00
111_L160_I0.9591.00
57_S65_S0.9551.00
112_Q141_Q0.9480.99
88_F111_L0.9470.99
87_S165_T0.9470.99
36_A55_S0.9410.99
58_L63_A0.9360.99
8_Y11_A0.9360.99
72_L162_I0.9340.99
18_S21_I0.9150.99
104_A107_I0.9140.99
31_N49_D0.9140.99
125_K140_L0.9080.99
101_Q159_V0.9060.99
11_A15_A0.8880.99
26_V30_V0.8820.99
74_L136_A0.8760.99
90_G94_S0.8700.99
88_F140_L0.8700.99
107_I144_A0.8600.99
53_L156_I0.8540.99
123_A126_T0.8480.99
46_A162_I0.8340.99
10_L13_I0.8320.99
36_A78_P0.8300.99
129_V133_S0.8300.99
8_Y15_A0.8220.99
91_A99_K0.8200.99
19_A23_A0.8100.98
53_L144_A0.8030.98
31_N47_T0.8030.98
114_D139_P0.8000.98
98_Y158_A0.7970.98
117_N126_T0.7960.98
112_Q118_T0.7940.98
12_A19_A0.7880.98
16_L20_T0.7840.98
14_L17_A0.7740.98
100_N157_Q0.7710.98
34_V53_L0.7690.98
20_T24_A0.7690.98
19_A22_Q0.7680.98
50_L68_H0.7640.98
34_V151_A0.7630.98
48_V142_V0.7610.98
53_L58_L0.7560.98
21_I25_D0.7550.97
27_T45_N0.7530.97
111_L121_T0.7520.97
55_S151_A0.7490.97
63_A146_T0.7460.97
38_P144_A0.7370.97
121_T140_L0.7310.97
84_V131_D0.7270.97
86_A164_Y0.7250.97
18_S23_A0.7220.97
125_K128_Q0.7170.97
50_L142_V0.7110.96
73_E135_S0.7090.96
92_A121_T0.7040.96
129_V132_S0.6990.96
10_L14_L0.6980.96
93_D108_Q0.6940.96
87_S123_A0.6940.96
109_L156_I0.6870.96
22_Q25_D0.6850.96
9_V12_A0.6830.95
57_S66_A0.6830.95
64_A67_W0.6820.95
78_P112_Q0.6780.95
49_D68_H0.6730.95
67_W112_Q0.6710.95
107_I151_A0.6700.95
119_L125_K0.6610.95
49_D144_A0.6600.95
88_F162_I0.6570.94
146_T149_G0.6540.94
11_A18_S0.6520.94
61_A147_V0.6520.94
55_S153_Q0.6420.94
29_T47_T0.6380.94
15_A18_S0.6380.94
85_T124_T0.6330.93
58_L149_G0.6230.93
8_Y19_A0.6140.92
51_G157_Q0.6120.92
17_A21_I0.6080.92
89_S161_S0.6070.92
28_I160_I0.6010.91
61_A106_N0.6010.91
14_L19_A0.5980.91
9_V16_L0.5970.91
59_M151_A0.5960.91
115_S141_Q0.5950.91
50_L110_E0.5910.91
65_S144_A0.5910.91
78_P81_T0.5890.91
79_V82_S0.5860.90
112_Q145_L0.5850.90
15_A20_T0.5790.90
101_Q157_Q0.5790.90
50_L70_V0.5740.89
78_P131_D0.5710.89
9_V13_I0.5680.89
29_T45_N0.5630.89
17_A20_T0.5630.89
10_L20_T0.5590.88
36_A82_S0.5580.88
50_L143_R0.5520.88
79_V133_S0.5520.88
10_L15_A0.5520.88
20_T23_A0.5520.88
83_R127_V0.5510.87
49_D52_D0.5510.87
17_A22_Q0.5490.87
10_L18_S0.5480.87
15_A21_I0.5470.87
144_A157_Q0.5460.87
98_Y119_L0.5450.87
10_L17_A0.5430.87
50_L53_L0.5430.87
26_V72_L0.5390.86
26_V33_K0.5360.86
83_R133_S0.5360.86
115_S128_Q0.5350.86
10_L21_I0.5330.86
119_L140_L0.5330.86
11_A17_A0.5310.86
140_L162_I0.5300.85
38_P160_I0.5300.85
86_A140_L0.5290.85
88_F138_F0.5290.85
42_S135_S0.5270.85
28_I47_T0.5260.85
40_T43_T0.5250.85
71_A92_A0.5230.85
93_D99_K0.5220.85
46_A90_G0.5210.84
75_T135_S0.5190.84
81_T85_T0.5190.84
95_T98_Y0.5180.84
34_V41_V0.5170.84
43_T81_T0.5120.83
98_Y109_L0.5100.83
35_V38_P0.5090.83
95_T108_Q0.5080.83
100_N103_T0.5040.82
48_V68_H0.5040.82
9_V15_A0.5030.82
100_N107_I0.5020.82
19_A24_A0.5020.82
97_Y101_Q0.5000.82
11_A20_T0.5000.82
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2xg5B 1 0.8144 100 0.259 Contact Map
2jmrA 1 0.8683 100 0.264 Contact Map
2jtyA 1 0.8862 100 0.283 Contact Map
2uy6B 2 0.8323 100 0.286 Contact Map
1pdkB 1 0.8024 100 0.32 Contact Map
3bfqG 1 0.7904 100 0.331 Contact Map
3bwuF 1 0.7066 99.9 0.363 Contact Map
2w07B 1 0.6826 99.9 0.367 Contact Map
4dwhB 1 0.7665 99.9 0.385 Contact Map
5afoA 1 0.982 99.9 0.388 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0072 seconds.