SYL - ECOLI - GREMLIN Contacts

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SYL - Leucine--tRNA ligase

UniProt:	P07813	Sequences: MQEQYRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGRLHMGHVRNYTIGDVIARYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSRELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVIDGCCWRCDTKVERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVNDYDNTLTVYTTRPDTFMGCTYLAVAAGHPLAQKAAENNPELAAFIDECRNTKVAEAEMATMEKKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPVILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTAMGVGERKVNYRLRDWGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILPEDVVMDGITSPIKADPEWAKTTVNGMPALRETDTFDTFMESSWYYARYTCPQYKEGMLDSEAANYWLPVDIYIGGIEHAIMHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVERDEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMTLEWQESGVEGANRFLKRVWKLVYEHTAKGDVAALNVDALTENQKALRRDVHKTIAKVTDDIGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQELKGEGDIDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHLVAKYLDGVTVRKVIYVPGKLLNLVVG	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10532
Length:	860 (831)
Sequences:	2153 (1075)
Seq/√Len:	37.3

ECOLI - SYL
BACSU - SYL
HALSA - SYL

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
821_T	824_Q	6.187	1.00
200_D	204_N	4.813	1.00
175_C	182_K	4.471	1.00
822_E	826_R	4.461	1.00
19_D	113_K	4.060	1.00
231_E	244_T	4.041	1.00
233_T	244_T	3.773	1.00
439_D	481_M	3.564	1.00
316_E	357_K	3.561	1.00
237_N	317_E	3.505	1.00
66_Q	71_K	3.483	1.00
144_Y	434_M	3.447	1.00
390_L	398_A	3.440	1.00
391_D	394_A	3.439	1.00
17_H	21_K	3.387	1.00
200_D	226_R	3.277	1.00
755_L	778_G	3.268	1.00
278_L	322_A	3.197	1.00
16_L	20_E	3.177	1.00
142_E	145_K	3.045	1.00
243_L	261_V	3.013	1.00
350_S	356_I	2.978	1.00
515_S	519_N	2.967	1.00
204_N	226_R	2.955	1.00
505_C	508_Y	2.933	1.00
153_T	187_E	2.916	1.00
799_S	815_T	2.890	1.00
6_R	9_E	2.876	1.00
207_D	221_R	2.854	1.00
812_A	832_E	2.817	1.00
611_E	614_Y	2.789	1.00
437_L	440_G	2.754	1.00
22_R	25_E	2.753	1.00
304_D	308_K	2.742	1.00
198_Y	550_D	2.667	1.00
702_R	752_E	2.623	1.00
69_L	713_T	2.621	1.00
610_H	614_Y	2.579	1.00
72_N	520_Y	2.570	1.00
278_L	303_V	2.568	1.00
233_T	242_T	2.565	1.00
161_N	181_T	2.512	1.00
343_Q	347_E	2.498	1.00
434_M	442_V	2.484	1.00
839_L	844_V	2.467	1.00
440_G	479_N	2.454	1.00
271_A	307_F	2.452	1.00
610_H	613_V	2.424	1.00
99_P	103_D	2.411	1.00
758_V	782_I	2.409	1.00
107_Y	110_N	2.400	1.00
33_E	71_K	2.385	1.00
437_L	479_N	2.372	1.00
142_E	447_D	2.361	1.00
402_K	406_M	2.355	1.00
176_C	179_C	2.346	1.00
275_N	303_V	2.334	1.00
232_I	403_L	2.309	1.00
308_K	317_E	2.306	1.00
404_T	410_E	2.265	0.99
404_T	411_R	2.258	0.99
440_G	478_V	2.254	0.99
256_C	318_I	2.235	0.99
284_E	301_K	2.227	0.99
822_E	851_P	2.201	0.99
445_T	449_Q	2.185	0.99
823_E	826_R	2.174	0.99
266_P	328_M	2.168	0.99
309_A	320_V	2.157	0.99
231_E	410_E	2.148	0.99
79_W	124_E	2.144	0.99
226_R	413_V	2.138	0.99
159_C	179_C	2.132	0.99
379_G	384_S	2.130	0.99
585_W	588_P	2.129	0.99
81_A	128_C	2.129	0.99
208_K	557_D	2.129	0.99
810_V	813_K	2.126	0.99
346_Y	356_I	2.123	0.99
849_Y	855_L	2.122	0.99
711_K	728_A	2.122	0.99
68_M	759_R	2.113	0.99
341_H	359_V	2.112	0.99
827_E	831_Q	2.104	0.99
154_S	192_F	2.087	0.99
398_A	401_D	2.084	0.99
79_W	109_K	2.084	0.99
826_R	847_V	2.076	0.99
704_D	708_T	2.074	0.99
504_T	522_L	2.074	0.99
514_D	517_A	2.059	0.99
824_Q	827_E	2.034	0.99
136_E	495_E	2.032	0.99
261_V	268_A	2.030	0.99
609_G	612_L	2.028	0.99
500_Y	545_H	2.027	0.99
232_I	245_V	2.018	0.99
819_D	824_Q	2.010	0.99
709_I	760_M	2.009	0.99
437_L	441_T	1.991	0.99
705_V	753_A	1.983	0.98
386_E	402_K	1.982	0.98
508_Y	511_G	1.980	0.98
28_E	517_A	1.974	0.98
441_T	479_N	1.964	0.98
755_L	759_R	1.964	0.98
707_K	797_E	1.962	0.98
573_A	618_S	1.959	0.98
612_L	615_T	1.958	0.98
584_N	587_S	1.957	0.98
710_A	714_D	1.951	0.98
709_I	756_A	1.947	0.98
159_C	181_T	1.947	0.98
545_H	556_S	1.934	0.98
676_L	733_M	1.930	0.98
446_P	449_Q	1.927	0.98
477_T	482_P	1.920	0.98
228_E	413_V	1.887	0.98
22_R	122_S	1.880	0.98
713_T	787_W	1.868	0.98
205_D	546_K	1.867	0.98
159_C	176_C	1.852	0.98
243_L	259_L	1.847	0.98
604_A	607_A	1.845	0.98
801_L	815_T	1.836	0.97
310_V	317_E	1.835	0.97
397_N	411_R	1.832	0.97
109_K	124_E	1.830	0.97
437_L	478_V	1.819	0.97
609_G	613_V	1.812	0.97
803_V	854_L	1.808	0.97
374_A	377_E	1.801	0.97
549_R	557_D	1.801	0.97
13_K	771_T	1.794	0.97
125_L	503_Y	1.789	0.97
812_A	834_L	1.788	0.97
583_R	586_V	1.774	0.97
437_L	443_M	1.773	0.97
176_C	181_T	1.772	0.97
193_I	494_M	1.769	0.97
387_F	402_K	1.763	0.97
141_T	444_P	1.763	0.97
65_Y	69_L	1.756	0.97
358_P	382_F	1.753	0.97
716_I	764_F	1.742	0.97
232_I	253_F	1.740	0.97
25_E	122_S	1.739	0.97
422_V	490_F	1.739	0.97
438_E	481_M	1.723	0.96
400_A	411_R	1.714	0.96
699_K	798_D	1.707	0.96
816_V	825_V	1.704	0.96
710_A	790_A	1.702	0.96
256_C	335_V	1.698	0.96
820_A	825_V	1.695	0.96
259_L	318_I	1.695	0.96
790_A	795_M	1.665	0.96
541_F	560_A	1.663	0.95
106_A	109_K	1.657	0.95
511_G	514_D	1.655	0.95
475_K	484_L	1.654	0.95
161_N	179_C	1.647	0.95
830_G	857_L	1.638	0.95
109_K	113_K	1.638	0.95
710_A	792_E	1.633	0.95
673_V	761_L	1.633	0.95
153_T	189_P	1.632	0.95
826_R	857_L	1.631	0.95
403_L	408_V	1.627	0.95
445_T	452_V	1.624	0.95
582_E	585_W	1.619	0.95
151_K	189_P	1.608	0.95
346_Y	350_S	1.603	0.94
801_L	813_K	1.584	0.94
830_G	844_V	1.581	0.94
402_K	405_A	1.573	0.94
313_L	402_K	1.566	0.94
736_L	753_A	1.564	0.94
570_L	655_T	1.564	0.94
261_V	271_A	1.555	0.94
382_F	388_N	1.542	0.93
605_K	610_H	1.542	0.93
392_H	396_F	1.539	0.93
609_G	614_Y	1.539	0.93
440_G	443_M	1.537	0.93
254_M	386_E	1.533	0.93
648_F	730_M	1.532	0.93
632_V	635_E	1.529	0.93
582_E	586_V	1.524	0.93
727_A	731_E	1.519	0.93
670_L	765_T	1.517	0.93
59_G	528_I	1.512	0.93
519_N	555_N	1.509	0.92
438_E	484_L	1.507	0.92
802_V	825_V	1.502	0.92
291_A	294_E	1.492	0.92
670_L	768_I	1.492	0.92
401_D	405_A	1.490	0.92
65_Y	713_T	1.489	0.92
253_F	403_L	1.473	0.91
311_H	314_T	1.470	0.91
235_N	408_V	1.470	0.91
604_A	610_H	1.469	0.91
831_Q	836_A	1.468	0.91
235_N	242_T	1.466	0.91
584_N	588_P	1.455	0.91
379_G	383_N	1.451	0.91
343_Q	346_Y	1.442	0.91
587_S	590_D	1.440	0.91
278_L	282_I	1.436	0.90
606_D	611_E	1.429	0.90
608_A	611_E	1.427	0.90
161_N	176_C	1.424	0.90
756_A	760_M	1.423	0.90
437_L	483_A	1.406	0.89
479_N	483_A	1.399	0.89
270_K	273_E	1.396	0.89
230_V	400_A	1.391	0.89
842_V	859_V	1.390	0.89
675_K	679_E	1.390	0.89
443_M	483_A	1.386	0.89
644_L	765_T	1.385	0.89
825_V	849_Y	1.384	0.89
819_D	852_G	1.383	0.89
826_R	830_G	1.379	0.89
606_D	610_H	1.379	0.89
142_E	553_M	1.373	0.88
441_T	478_V	1.365	0.88
701_L	736_L	1.363	0.88
606_D	609_G	1.359	0.88
138_K	447_D	1.358	0.88
453_I	456_E	1.352	0.88
712_V	726_I	1.350	0.87
604_A	608_A	1.345	0.87
114_M	635_E	1.338	0.87
257_T	357_K	1.338	0.87
194_K	197_A	1.337	0.87
830_G	847_V	1.336	0.87
705_V	709_I	1.332	0.87
673_V	765_T	1.331	0.87
701_L	739_A	1.323	0.86
476_T	483_A	1.322	0.86
435_V	476_T	1.320	0.86
847_V	857_L	1.309	0.86
283_D	286_R	1.308	0.86
708_T	712_V	1.305	0.86
513_L	518_A	1.305	0.86
374_A	379_G	1.304	0.86
839_L	857_L	1.302	0.85
607_A	611_E	1.302	0.85
149_V	193_I	1.301	0.85
215_T	531_I	1.299	0.85
50_M	53_V	1.298	0.85
200_D	415_Y	1.293	0.85
398_A	402_K	1.291	0.85
678_Y	775_E	1.288	0.85
380_V	391_D	1.287	0.85
305_T	322_A	1.287	0.85
751_Q	755_L	1.285	0.85
605_K	608_A	1.285	0.85
361_L	382_F	1.279	0.84
694_L	749_L	1.274	0.84
135_W	138_K	1.270	0.84
197_A	200_D	1.267	0.84
705_V	732_L	1.266	0.84
584_N	590_D	1.263	0.84
793_K	796_V	1.261	0.84
385_G	388_N	1.260	0.84
162_D	179_C	1.260	0.84
205_D	208_K	1.258	0.83
63_A	118_G	1.258	0.83
611_E	615_T	1.258	0.83
714_D	718_R	1.257	0.83
761_L	769_C	1.257	0.83
400_A	404_T	1.251	0.83
241_N	270_K	1.246	0.83
817_P	820_A	1.243	0.83
387_F	399_I	1.237	0.82
705_V	756_A	1.231	0.82
513_L	548_M	1.227	0.82
701_L	735_K	1.223	0.82
696_E	752_E	1.221	0.82
443_M	479_N	1.210	0.81
607_A	610_H	1.209	0.81
845_R	859_V	1.208	0.81
35_Y	66_Q	1.206	0.81
33_E	66_Q	1.206	0.81
818_V	852_G	1.201	0.80
280_A	283_D	1.200	0.80
736_L	757_V	1.199	0.80
361_L	380_V	1.198	0.80
102_Y	129_T	1.197	0.80
756_A	759_R	1.195	0.80
575_Y	618_S	1.195	0.80
440_G	481_M	1.195	0.80
585_W	590_D	1.194	0.80
823_E	827_E	1.192	0.80
316_E	355_N	1.192	0.80
313_L	337_A	1.189	0.80
834_L	837_K	1.183	0.79
397_N	401_D	1.182	0.79
582_E	587_S	1.180	0.79
603_K	607_A	1.180	0.79
676_L	754_L	1.169	0.79
383_N	388_N	1.169	0.79
704_D	735_K	1.166	0.78
803_V	810_V	1.166	0.78
217_K	221_R	1.165	0.78
162_D	176_C	1.164	0.78
260_A	326_V	1.158	0.78
606_D	613_V	1.156	0.78
66_Q	69_L	1.152	0.78
575_Y	585_W	1.148	0.77
136_E	490_F	1.148	0.77
159_C	180_D	1.147	0.77
706_H	709_I	1.145	0.77
440_G	483_A	1.140	0.77
253_F	313_L	1.140	0.77
702_R	794_A	1.139	0.77
490_F	495_E	1.138	0.77
13_K	774_Q	1.137	0.77
780_G	785_A	1.135	0.76
138_K	553_M	1.133	0.76
465_S	468_K	1.128	0.76
803_V	853_K	1.125	0.76
474_A	484_L	1.124	0.76
162_D	181_T	1.117	0.75
604_A	611_E	1.113	0.75
826_R	849_Y	1.108	0.75
142_E	551_A	1.107	0.75
501_A	518_A	1.107	0.75
99_P	456_E	1.105	0.75
604_A	609_G	1.104	0.74
501_A	522_L	1.103	0.74
125_L	132_Y	1.101	0.74
39_S	75_Q	1.097	0.74
138_K	142_E	1.096	0.74
155_A	185_R	1.093	0.74
37_C	62_I	1.090	0.73
758_V	776_L	1.086	0.73
24_F	783_D	1.085	0.73
673_V	757_V	1.084	0.73
833_H	836_A	1.084	0.73
474_A	487_T	1.083	0.73
762_N	782_I	1.081	0.73
260_A	337_A	1.080	0.73
603_K	610_H	1.079	0.73
590_D	594_E	1.076	0.73
677_V	758_V	1.074	0.72
443_M	478_V	1.069	0.72
375_L	379_G	1.068	0.72
522_L	556_S	1.067	0.72
231_E	412_K	1.066	0.72
478_V	483_A	1.066	0.72
569_V	629_D	1.065	0.72
825_V	854_L	1.065	0.72
844_V	847_V	1.064	0.72
358_P	361_L	1.061	0.71
23_T	783_D	1.060	0.71
299_E	351_K	1.057	0.71
803_V	813_K	1.051	0.71
125_L	129_T	1.051	0.71
677_V	754_L	1.048	0.70
291_A	296_A	1.045	0.70
708_T	760_M	1.045	0.70
141_T	447_D	1.044	0.70
586_V	590_D	1.043	0.70
143_L	551_A	1.040	0.70
375_L	378_K	1.039	0.70
605_K	611_E	1.037	0.70
816_V	828_R	1.037	0.70
500_Y	554_V	1.036	0.70
268_A	271_A	1.029	0.69
518_A	555_N	1.028	0.69
14_V	770_F	1.027	0.69
155_A	187_E	1.027	0.69
445_T	448_D	1.026	0.69
214_D	218_T	1.025	0.69
759_R	785_A	1.025	0.69
5_Y	11_E	1.024	0.69
154_S	190_Q	1.022	0.69
59_G	75_Q	1.021	0.68
245_V	335_V	1.020	0.68
228_E	411_R	1.019	0.68
14_V	771_T	1.018	0.68
34_K	520_Y	1.016	0.68
213_P	216_V	1.014	0.68
822_E	849_Y	1.013	0.68
824_Q	828_R	1.011	0.68
277_E	280_A	1.010	0.68
103_D	106_A	1.010	0.68
340_G	346_Y	1.006	0.67
379_G	382_F	1.003	0.67
704_D	707_K	1.002	0.67
603_K	606_D	1.002	0.67
15_Q	767_H	1.000	0.67
258_Y	392_H	1.000	0.67
701_L	753_A	0.999	0.67
711_K	731_E	0.999	0.67
822_E	827_E	0.999	0.67
844_V	859_V	0.998	0.67
438_E	482_P	0.997	0.67
476_T	481_M	0.997	0.67
594_E	604_A	0.995	0.66
705_V	749_L	0.995	0.66
802_V	852_G	0.994	0.66
758_V	772_L	0.993	0.66
806_V	829_A	0.990	0.66
253_F	337_A	0.989	0.66
729_I	757_V	0.988	0.66
343_Q	374_A	0.988	0.66
501_A	548_M	0.987	0.66
803_V	825_V	0.986	0.66
481_M	484_L	0.986	0.66
303_V	329_E	0.984	0.66
359_V	363_A	0.982	0.65
280_A	284_E	0.982	0.65
98_A	102_Y	0.978	0.65
259_L	335_V	0.976	0.65
145_K	447_D	0.976	0.65
715_D	724_T	0.974	0.65
236_V	241_N	0.974	0.65
284_E	287_N	0.968	0.64
341_H	358_P	0.966	0.64
697_N	752_E	0.962	0.64
797_E	815_T	0.962	0.64
791_D	794_A	0.961	0.64
387_F	392_H	0.959	0.64
545_H	554_V	0.958	0.63
106_A	110_N	0.958	0.63
761_L	765_T	0.957	0.63
66_Q	717_G	0.954	0.63
576_Y	586_V	0.954	0.63
705_V	708_T	0.953	0.63
69_L	789_V	0.952	0.63
204_N	207_D	0.952	0.63
729_I	760_M	0.949	0.63
126_A	129_T	0.948	0.63
703_R	797_E	0.947	0.63
65_Y	717_G	0.945	0.62
814_I	832_E	0.944	0.62
711_K	715_D	0.938	0.62
435_V	483_A	0.937	0.62
68_M	786_P	0.936	0.62
511_G	515_S	0.936	0.62
475_K	482_P	0.935	0.62
237_N	310_V	0.934	0.61
281_F	301_K	0.934	0.61
609_G	615_T	0.933	0.61
618_S	624_K	0.932	0.61
581_G	611_E	0.929	0.61
76_P	121_W	0.928	0.61
490_F	494_M	0.921	0.60
259_L	337_A	0.920	0.60
363_A	380_V	0.919	0.60
650_S	656_L	0.919	0.60
89_A	100_W	0.918	0.60
401_D	411_R	0.915	0.60
728_A	731_E	0.914	0.60
57_T	117_F	0.911	0.60
835_V	838_Y	0.910	0.59
505_C	517_A	0.909	0.59
102_Y	106_A	0.908	0.59
62_I	720_Q	0.908	0.59
373_Q	376_T	0.906	0.59
376_T	379_G	0.906	0.59
172_I	535_I	0.905	0.59
645_F	649_A	0.903	0.59
602_V	605_K	0.901	0.59
41_L	560_A	0.901	0.59
95_T	100_W	0.901	0.59
633_M	642_V	0.900	0.59
470_D	475_K	0.900	0.59
582_E	588_P	0.898	0.58
769_C	782_I	0.898	0.58
362_A	365_G	0.897	0.58
288_T	291_A	0.897	0.58
575_Y	625_N	0.896	0.58
834_L	838_Y	0.892	0.58
590_D	607_A	0.891	0.58
323_A	335_V	0.891	0.58
435_V	446_P	0.890	0.58
782_I	785_A	0.890	0.58
269_Q	282_I	0.890	0.58
293_A	297_T	0.888	0.58
844_V	857_L	0.888	0.58
254_M	313_L	0.887	0.57
346_Y	374_A	0.883	0.57
507_Q	517_A	0.883	0.57
172_I	176_C	0.882	0.57
806_V	837_K	0.882	0.57
159_C	162_D	0.876	0.57
232_I	259_L	0.875	0.56
7_P	667_N	0.873	0.56
841_G	844_V	0.870	0.56
490_F	501_A	0.869	0.56
669_F	733_M	0.866	0.56
829_A	847_V	0.862	0.55
576_Y	582_E	0.862	0.55
151_K	442_V	0.862	0.55
236_V	240_D	0.861	0.55
156_V	165_V	0.861	0.55
629_D	656_L	0.861	0.55
583_R	618_S	0.861	0.55
214_D	226_R	0.860	0.55
518_A	556_S	0.859	0.55
362_A	366_S	0.856	0.55
79_W	113_K	0.855	0.55
605_K	612_L	0.854	0.55
341_H	381_L	0.853	0.54
314_T	317_E	0.850	0.54
272_A	307_F	0.850	0.54
151_K	436_T	0.847	0.54
386_E	399_I	0.847	0.54
221_R	541_F	0.844	0.54
69_L	717_G	0.844	0.54
152_K	192_F	0.842	0.54
346_Y	373_Q	0.841	0.53
587_S	625_N	0.841	0.53
673_V	716_I	0.840	0.53
829_A	849_Y	0.839	0.53
176_C	180_D	0.836	0.53
254_M	384_S	0.836	0.53
27_T	30_E	0.836	0.53
781_D	784_N	0.836	0.53
603_K	608_A	0.833	0.53
515_S	555_N	0.832	0.53
645_F	662_G	0.832	0.53
800_T	818_V	0.831	0.53
250_P	396_F	0.831	0.53
839_L	859_V	0.830	0.52
832_E	835_V	0.829	0.52
802_V	816_V	0.829	0.52
216_V	531_I	0.828	0.52
435_V	440_G	0.823	0.52
435_V	479_N	0.823	0.52
358_P	362_A	0.823	0.52
627_G	631_Q	0.822	0.52
839_L	843_T	0.822	0.52
59_G	325_F	0.821	0.52
360_I	381_L	0.821	0.52
669_F	730_M	0.821	0.52
75_Q	119_Y	0.821	0.52
605_K	609_G	0.819	0.51
698_Q	749_L	0.819	0.51
179_C	544_F	0.819	0.51
602_V	608_A	0.818	0.51
610_H	615_T	0.818	0.51
34_K	525_D	0.817	0.51
393_E	397_N	0.815	0.51
701_L	743_G	0.815	0.51
195_I	539_L	0.814	0.51
29_D	520_Y	0.813	0.51
234_F	341_H	0.813	0.51
827_E	830_G	0.811	0.51
289_K	295_M	0.810	0.51
393_E	396_F	0.810	0.51
203_L	226_R	0.810	0.51
185_R	289_K	0.809	0.51
589_V	594_E	0.809	0.51
263_A	293_A	0.809	0.51
564_L	720_Q	0.808	0.51
381_L	392_H	0.808	0.51
381_L	396_F	0.808	0.51
341_H	382_F	0.807	0.50
56_Y	79_W	0.806	0.50
17_H	781_D	0.805	0.50
476_T	482_P	0.804	0.50
17_H	20_E	0.803	0.50
564_L	653_D	0.803	0.50
562_Q	720_Q	0.802	0.50
468_K	484_L	0.801	0.50
770_F	781_D	0.801	0.50
435_V	445_T	0.801	0.50
177_W	492_T	0.800	0.50
698_Q	701_L	0.800	0.50
251_D	396_F	0.798	0.50
804_V	828_R	0.798	0.50
570_L	617_M	0.798	0.50
726_I	764_F	0.797	0.50
230_V	403_L	0.795	0.49
86_A	100_W	0.795	0.49
313_L	399_I	0.795	0.49
564_L	657_E	0.794	0.49
583_R	619_K	0.793	0.49
394_A	397_N	0.793	0.49
196_T	199_A	0.792	0.49
55_N	119_Y	0.791	0.49
244_T	412_K	0.789	0.49
237_N	308_K	0.789	0.49
594_E	607_A	0.789	0.49
434_M	444_P	0.788	0.49
292_E	296_A	0.787	0.49
163_Q	179_C	0.786	0.49
470_D	473_W	0.784	0.48
261_V	307_F	0.784	0.48
77_I	108_M	0.783	0.48
430_A	495_E	0.782	0.48
494_M	535_I	0.781	0.48
92_K	584_N	0.781	0.48
798_D	819_D	0.780	0.48
825_V	828_R	0.780	0.48
175_C	179_C	0.779	0.48
700_A	738_K	0.779	0.48
470_D	474_A	0.777	0.48
381_L	386_E	0.776	0.48
161_N	180_D	0.775	0.48
803_V	852_G	0.775	0.48
110_N	114_M	0.775	0.48
396_F	399_I	0.774	0.48
806_V	834_L	0.773	0.47
250_P	400_A	0.772	0.47
201_E	549_R	0.772	0.47
66_Q	722_F	0.771	0.47
401_D	404_T	0.771	0.47
759_R	778_G	0.770	0.47
575_Y	583_R	0.769	0.47
479_N	482_P	0.768	0.47
503_Y	705_V	0.768	0.47
501_A	545_H	0.767	0.47
762_N	769_C	0.766	0.47
216_V	565_C	0.766	0.47
79_W	108_M	0.765	0.47
435_V	478_V	0.761	0.46
248_T	333_G	0.760	0.46
29_D	32_K	0.760	0.46
664_E	668_R	0.758	0.46
702_R	706_H	0.757	0.46
678_Y	682_A	0.756	0.46
88_G	179_C	0.756	0.46
313_L	386_E	0.754	0.46
279_A	283_D	0.753	0.46
665_G	668_R	0.753	0.46
143_L	544_F	0.753	0.46
476_T	479_N	0.752	0.46
146_K	550_D	0.752	0.46
121_W	124_E	0.752	0.46
313_L	403_L	0.751	0.45
381_L	387_F	0.751	0.45
17_H	774_Q	0.750	0.45
631_Q	635_E	0.749	0.45
369_D	372_Q	0.749	0.45
583_R	587_S	0.749	0.45
257_T	349_A	0.749	0.45
84_L	91_V	0.748	0.45
67_R	118_G	0.748	0.45
88_G	181_T	0.747	0.45
139_F	436_T	0.746	0.45
41_L	541_F	0.746	0.45
820_A	824_Q	0.745	0.45
274_N	277_E	0.745	0.45
782_I	786_P	0.745	0.45
384_S	388_N	0.745	0.45
820_A	828_R	0.743	0.45
813_K	854_L	0.742	0.45
12_S	16_L	0.742	0.45
359_V	384_S	0.741	0.45
377_E	384_S	0.740	0.45
473_W	484_L	0.739	0.44
430_A	494_M	0.739	0.44
833_H	837_K	0.739	0.44
494_M	544_F	0.738	0.44
41_L	536_M	0.738	0.44
457_D	470_D	0.737	0.44
360_I	379_G	0.736	0.44
53_V	115_L	0.736	0.44
300_K	347_E	0.736	0.44
820_A	852_G	0.735	0.44
602_V	607_A	0.735	0.44
828_R	831_Q	0.733	0.44
845_R	857_L	0.732	0.44
285_C	301_K	0.732	0.44
340_G	357_K	0.732	0.44
594_E	605_K	0.731	0.44
591_A	604_A	0.729	0.44
281_F	285_C	0.728	0.43
423_S	489_T	0.726	0.43
585_W	589_V	0.724	0.43
289_K	294_E	0.724	0.43
835_V	844_V	0.724	0.43
437_L	481_M	0.723	0.43
272_A	322_A	0.723	0.43
285_C	324_N	0.722	0.43
413_V	541_F	0.722	0.43
35_Y	62_I	0.722	0.43
644_L	730_M	0.721	0.43
759_R	762_N	0.720	0.43
256_C	323_A	0.720	0.43
126_A	503_Y	0.720	0.43
30_E	33_E	0.719	0.43
501_A	554_V	0.719	0.43
812_A	836_A	0.719	0.43
465_S	470_D	0.718	0.43
143_L	148_L	0.718	0.43
98_A	456_E	0.718	0.43
136_E	494_M	0.717	0.43
346_Y	358_P	0.716	0.42
468_K	487_T	0.715	0.42
88_G	100_W	0.715	0.42
441_T	483_A	0.714	0.42
564_L	656_L	0.713	0.42
262_A	328_M	0.712	0.42
415_Y	764_F	0.712	0.42
143_L	547_L	0.712	0.42
134_R	138_K	0.711	0.42
303_V	322_A	0.711	0.42
283_D	287_N	0.708	0.42
149_V	423_S	0.708	0.42
378_K	384_S	0.707	0.42
662_G	666_A	0.707	0.42
591_A	594_E	0.707	0.42
435_V	485_R	0.705	0.41
159_C	166_L	0.704	0.41
847_V	855_L	0.704	0.41
39_S	48_L	0.704	0.41
380_V	384_S	0.704	0.41
765_T	768_I	0.703	0.41
32_K	818_V	0.703	0.41
246_Y	414_N	0.702	0.41
569_V	650_S	0.702	0.41
512_M	553_M	0.702	0.41
6_R	667_N	0.701	0.41
41_L	762_N	0.701	0.41
847_V	859_V	0.700	0.41
663_V	726_I	0.699	0.41
773_W	777_K	0.699	0.41
340_G	358_P	0.698	0.41
116_G	521_W	0.698	0.41
69_L	787_W	0.698	0.41
500_Y	522_L	0.696	0.41
704_D	731_E	0.696	0.41
246_Y	473_W	0.696	0.41
360_I	722_F	0.696	0.41
260_A	323_A	0.696	0.41
377_E	392_H	0.695	0.41
373_Q	379_G	0.695	0.41
23_T	784_N	0.695	0.41
259_L	414_N	0.695	0.41
594_E	608_A	0.694	0.41
704_D	736_L	0.693	0.40
56_Y	112_L	0.693	0.40
359_V	364_D	0.692	0.40
335_V	392_H	0.692	0.40
602_V	610_H	0.691	0.40
130_P	449_Q	0.691	0.40
591_A	596_D	0.690	0.40
573_A	586_V	0.690	0.40
160_P	184_E	0.689	0.40
243_L	334_A	0.688	0.40
657_E	720_Q	0.688	0.40
162_D	182_K	0.687	0.40
96_A	456_E	0.687	0.40
56_Y	108_M	0.686	0.40
366_S	382_F	0.684	0.40
314_T	385_G	0.684	0.40
677_V	772_L	0.684	0.40
62_I	66_Q	0.683	0.40
535_I	569_V	0.683	0.40
268_A	307_F	0.683	0.40
837_K	840_D	0.681	0.39
516_E	519_N	0.681	0.39
820_A	827_E	0.681	0.39
128_C	133_Y	0.680	0.39
377_E	380_V	0.680	0.39
116_G	767_H	0.679	0.39
615_T	618_S	0.679	0.39
465_S	487_T	0.679	0.39
618_S	625_N	0.679	0.39
252_T	338_V	0.677	0.39
480_G	483_A	0.676	0.39
839_L	842_V	0.676	0.39
177_W	493_F	0.676	0.39
652_A	722_F	0.676	0.39
822_E	825_V	0.675	0.39
569_V	656_L	0.675	0.39
733_M	757_V	0.674	0.39
627_G	650_S	0.674	0.39
436_T	441_T	0.674	0.39
108_M	112_L	0.674	0.39
50_M	630_P	0.673	0.39
109_K	112_L	0.673	0.39
603_K	611_E	0.673	0.39
15_Q	18_W	0.671	0.39
390_L	395_A	0.671	0.39
678_Y	681_T	0.670	0.39
106_A	113_K	0.668	0.38
399_I	402_K	0.668	0.38
144_Y	442_V	0.667	0.38
806_V	810_V	0.667	0.38
610_H	617_M	0.667	0.38
275_N	286_R	0.666	0.38
186_K	298_M	0.664	0.38
717_G	760_M	0.663	0.38
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609_G	617_M	0.662	0.38
388_N	804_V	0.662	0.38
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573_A	585_W	0.661	0.38
179_C	182_K	0.661	0.38
360_I	392_H	0.660	0.38
596_D	604_A	0.660	0.38
246_Y	413_V	0.660	0.38
235_N	310_V	0.660	0.38
131_E	509_K	0.659	0.38
362_A	375_L	0.659	0.38
675_K	678_Y	0.659	0.38
674_W	768_I	0.658	0.38
139_F	548_M	0.657	0.37
585_W	616_G	0.657	0.37
755_L	776_L	0.657	0.37
504_T	560_A	0.657	0.37
192_F	493_F	0.656	0.37
71_K	717_G	0.654	0.37
170_Q	491_D	0.654	0.37
200_D	228_E	0.654	0.37
248_T	344_R	0.653	0.37
136_E	430_A	0.653	0.37
807_N	842_V	0.652	0.37
58_I	656_L	0.652	0.37
160_P	179_C	0.652	0.37
175_C	181_T	0.652	0.37
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802_V	850_V	0.652	0.37
738_K	857_L	0.651	0.37
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33_E	130_P	0.648	0.37
268_A	322_A	0.648	0.37
751_Q	776_L	0.647	0.37
91_V	149_V	0.647	0.37
136_E	656_L	0.645	0.36
95_T	492_T	0.645	0.36
169_E	420_W	0.643	0.36
817_P	824_Q	0.642	0.36
219_M	668_R	0.642	0.36
572_D	618_S	0.642	0.36
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366_S	372_Q	0.640	0.36
172_I	536_M	0.640	0.36
194_K	846_K	0.638	0.36
489_T	492_T	0.638	0.36
361_L	365_G	0.637	0.36
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131_E	453_I	0.636	0.36
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826_R	851_P	0.633	0.35
524_V	560_A	0.633	0.35
816_V	820_A	0.632	0.35
55_N	59_G	0.632	0.35
423_S	486_E	0.631	0.35
233_T	410_E	0.631	0.35
159_C	182_K	0.631	0.35
22_R	26_V	0.631	0.35
108_M	627_G	0.630	0.35
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88_G	441_T	0.630	0.35
629_D	642_V	0.629	0.35
264_G	325_F	0.629	0.35
347_E	350_S	0.628	0.35
149_V	846_K	0.627	0.35
667_N	671_K	0.627	0.35
209_L	563_L	0.627	0.35
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366_S	369_D	0.626	0.35
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508_Y	513_L	0.625	0.35
811_R	838_Y	0.625	0.35
333_G	342_D	0.625	0.35
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205_D	557_D	0.624	0.35
712_V	725_A	0.623	0.35
432_I	488_D	0.623	0.35
582_E	618_S	0.622	0.35
436_T	484_L	0.622	0.35
294_E	298_M	0.622	0.35
56_Y	76_P	0.622	0.35
262_A	282_I	0.622	0.35
439_D	479_N	0.621	0.34
149_V	179_C	0.620	0.34
807_N	853_K	0.620	0.34
725_A	764_F	0.619	0.34
361_L	366_S	0.618	0.34
341_H	346_Y	0.617	0.34
378_K	392_H	0.616	0.34
758_V	816_V	0.616	0.34
232_I	318_I	0.615	0.34
12_S	19_D	0.615	0.34
589_V	596_D	0.614	0.34
817_P	821_T	0.613	0.34
346_Y	376_T	0.613	0.34
88_G	162_D	0.613	0.34
697_N	700_A	0.613	0.34
252_T	333_G	0.612	0.34
125_L	509_K	0.612	0.34
378_K	393_E	0.611	0.34
268_A	272_A	0.611	0.34
571_A	625_N	0.610	0.34
695_T	698_Q	0.610	0.34
336_M	344_R	0.610	0.34
816_V	852_G	0.610	0.34
806_V	835_V	0.610	0.34
59_G	119_Y	0.608	0.33
146_K	551_A	0.608	0.33
804_V	844_V	0.608	0.33
268_A	282_I	0.606	0.33
798_D	817_P	0.606	0.33
590_D	596_D	0.605	0.33
478_V	481_M	0.604	0.33
709_I	729_I	0.604	0.33
245_V	309_A	0.604	0.33
584_N	618_S	0.603	0.33
346_Y	364_D	0.603	0.33
367_E	372_Q	0.602	0.33
236_V	242_T	0.602	0.33
253_F	790_A	0.602	0.33
38_L	41_L	0.602	0.33
803_V	807_N	0.602	0.33
513_L	553_M	0.601	0.33
261_V	272_A	0.601	0.33
806_V	812_A	0.600	0.33
505_C	513_L	0.600	0.33
449_Q	453_I	0.599	0.33
179_C	573_A	0.599	0.33
474_A	503_Y	0.599	0.33
805_Q	808_G	0.599	0.33
801_L	814_I	0.599	0.33
178_R	497_S	0.598	0.33
159_C	175_C	0.598	0.33
611_E	616_G	0.597	0.33
26_V	520_Y	0.597	0.33
508_Y	514_D	0.597	0.33
148_L	190_Q	0.596	0.33
68_M	762_N	0.596	0.33
227_S	333_G	0.596	0.33
333_G	344_R	0.595	0.32
398_A	406_M	0.595	0.32
582_E	590_D	0.595	0.32
394_A	398_A	0.594	0.32
41_L	503_Y	0.593	0.32
830_G	836_A	0.593	0.32
128_C	492_T	0.593	0.32
176_C	576_Y	0.592	0.32
547_L	551_A	0.591	0.32
680_H	683_K	0.590	0.32
180_D	573_A	0.590	0.32
387_F	395_A	0.590	0.32
592_I	607_A	0.590	0.32
440_G	484_L	0.589	0.32
74_L	850_V	0.588	0.32
273_E	276_P	0.588	0.32
627_G	656_L	0.587	0.32
9_E	12_S	0.587	0.32
591_A	773_W	0.587	0.32
826_R	844_V	0.586	0.32
256_C	336_M	0.585	0.32
53_V	629_D	0.585	0.32
755_L	777_K	0.585	0.32
574_F	855_L	0.585	0.32
435_V	452_V	0.585	0.32
9_E	13_K	0.585	0.32
346_Y	365_G	0.584	0.32
325_F	490_F	0.584	0.32
486_E	489_T	0.584	0.32
358_P	374_A	0.583	0.32
154_S	497_S	0.583	0.32
128_C	493_F	0.582	0.31
95_T	99_P	0.581	0.31
326_V	333_G	0.581	0.31
218_T	221_R	0.581	0.31
346_Y	359_V	0.581	0.31
463_I	469_A	0.581	0.31
186_K	832_E	0.581	0.31
8_E	635_E	0.580	0.31
390_L	399_I	0.579	0.31
606_D	614_Y	0.579	0.31
648_F	724_T	0.579	0.31
278_L	413_V	0.579	0.31
57_T	147_G	0.579	0.31
460_M	467_I	0.579	0.31
210_D	217_K	0.578	0.31
716_I	725_A	0.577	0.31
836_A	841_G	0.577	0.31
74_L	116_G	0.577	0.31
264_G	289_K	0.576	0.31
802_V	807_N	0.576	0.31
569_V	627_G	0.575	0.31
231_E	321_W	0.575	0.31
462_G	469_A	0.574	0.31
145_K	194_K	0.573	0.31
430_A	544_F	0.573	0.31
673_V	729_I	0.573	0.31
554_V	842_V	0.572	0.31
200_D	705_V	0.571	0.31
607_A	613_V	0.571	0.31
199_A	203_L	0.571	0.31
359_V	362_A	0.571	0.31
245_V	852_G	0.571	0.31
589_V	592_I	0.570	0.31
349_A	354_L	0.569	0.30
92_K	625_N	0.569	0.30
743_G	753_A	0.569	0.30
176_C	571_A	0.569	0.30
798_D	818_V	0.567	0.30
35_Y	720_Q	0.567	0.30
336_M	342_D	0.566	0.30
500_Y	556_S	0.566	0.30
712_V	732_L	0.566	0.30
248_T	342_D	0.566	0.30
258_Y	262_A	0.566	0.30
236_V	309_A	0.566	0.30
170_Q	492_T	0.566	0.30
822_E	855_L	0.566	0.30
595_R	602_V	0.566	0.30
593_V	596_D	0.564	0.30
473_W	478_V	0.564	0.30
358_P	368_P	0.563	0.30
592_I	608_A	0.562	0.30
536_M	539_L	0.562	0.30
437_L	476_T	0.562	0.30
284_E	324_N	0.561	0.30
239_Y	270_K	0.561	0.30
330_Y	333_G	0.561	0.30
521_W	767_H	0.560	0.30
457_D	461_D	0.560	0.30
109_K	762_N	0.560	0.30
602_V	606_D	0.559	0.30
363_A	382_F	0.558	0.30
441_T	445_T	0.558	0.30
804_V	855_L	0.558	0.30
121_W	621_S	0.557	0.30
414_N	662_G	0.557	0.30
76_P	124_E	0.557	0.30
377_E	381_L	0.557	0.30
236_V	239_Y	0.557	0.30
54_R	100_W	0.557	0.30
177_W	489_T	0.556	0.29
125_L	615_T	0.556	0.29
814_I	828_R	0.555	0.29
553_M	843_T	0.555	0.29
150_Y	419_D	0.554	0.29
475_K	478_V	0.554	0.29
378_K	383_N	0.554	0.29
92_K	188_I	0.554	0.29
381_L	384_S	0.554	0.29
259_L	833_H	0.554	0.29
36_Y	76_P	0.553	0.29
349_A	521_W	0.553	0.29
215_T	256_C	0.553	0.29
641_T	667_N	0.552	0.29
725_A	732_L	0.552	0.29
53_V	57_T	0.552	0.29
101_T	104_N	0.551	0.29
134_R	508_Y	0.551	0.29
6_R	375_L	0.551	0.29
699_K	799_S	0.551	0.29
41_L	127_T	0.551	0.29
758_V	769_C	0.551	0.29
435_V	482_P	0.550	0.29
16_L	19_D	0.550	0.29
289_K	325_F	0.550	0.29
718_R	721_T	0.549	0.29
170_Q	177_W	0.549	0.29
27_T	520_Y	0.549	0.29
200_D	203_L	0.548	0.29
258_Y	400_A	0.547	0.29
259_L	309_A	0.547	0.29
836_A	839_L	0.546	0.29
47_R	103_D	0.546	0.29
703_R	854_L	0.544	0.29
54_R	108_M	0.544	0.29
176_C	421_G	0.544	0.29
272_A	276_P	0.544	0.29
79_W	119_Y	0.543	0.29
679_E	683_K	0.543	0.29
146_K	150_Y	0.543	0.29
594_E	602_V	0.542	0.28
603_K	613_V	0.542	0.28
471_P	475_K	0.542	0.28
814_I	817_P	0.542	0.28
264_G	293_A	0.541	0.28
258_Y	343_Q	0.541	0.28
709_I	790_A	0.541	0.28
262_A	266_P	0.541	0.28
356_I	369_D	0.541	0.28
709_I	732_L	0.541	0.28
712_V	729_I	0.540	0.28
810_V	856_N	0.540	0.28
837_K	842_V	0.540	0.28
608_A	613_V	0.540	0.28
434_M	486_E	0.540	0.28
75_Q	118_G	0.539	0.28
397_N	400_A	0.539	0.28
804_V	857_L	0.539	0.28
736_L	739_A	0.539	0.28
501_A	556_S	0.538	0.28
131_E	507_Q	0.537	0.28
659_Q	662_G	0.537	0.28
564_L	721_T	0.537	0.28
246_Y	834_L	0.537	0.28
592_I	602_V	0.537	0.28
629_D	639_A	0.536	0.28
227_S	344_R	0.536	0.28
335_V	403_L	0.536	0.28
611_E	617_M	0.536	0.28
375_L	384_S	0.535	0.28
698_Q	739_A	0.535	0.28
546_K	557_D	0.535	0.28
838_Y	857_L	0.535	0.28
390_L	405_A	0.535	0.28
264_G	272_A	0.534	0.28
535_I	541_F	0.534	0.28
256_C	337_A	0.533	0.28
150_Y	656_L	0.533	0.28
839_L	845_R	0.533	0.28
583_R	588_P	0.532	0.28
130_P	492_T	0.531	0.28
252_T	336_M	0.531	0.28
167_A	620_M	0.531	0.28
92_K	178_R	0.530	0.28
508_Y	517_A	0.530	0.28
205_D	209_L	0.530	0.28
707_K	736_L	0.530	0.28
25_E	762_N	0.530	0.28
115_L	359_V	0.530	0.28
316_E	385_G	0.529	0.28
88_G	440_G	0.529	0.28
182_K	287_N	0.529	0.28
676_L	739_A	0.528	0.27
236_V	271_A	0.527	0.27
666_A	727_A	0.527	0.27
826_R	843_T	0.527	0.27
84_L	650_S	0.527	0.27
346_Y	380_V	0.527	0.27
59_G	136_E	0.526	0.27
77_I	154_S	0.526	0.27
95_T	103_D	0.526	0.27
33_E	410_E	0.526	0.27
732_L	760_M	0.526	0.27
56_Y	109_K	0.525	0.27
63_A	66_Q	0.525	0.27
814_I	825_V	0.525	0.27
435_V	441_T	0.525	0.27
263_A	326_V	0.524	0.27
22_R	817_P	0.524	0.27
290_V	298_M	0.524	0.27
733_M	790_A	0.524	0.27
610_H	628_I	0.524	0.27
95_T	467_I	0.524	0.27
316_E	789_V	0.524	0.27
668_R	725_A	0.524	0.27
248_T	326_V	0.523	0.27
709_I	713_T	0.523	0.27
812_A	835_V	0.523	0.27
378_K	382_F	0.523	0.27
379_G	388_N	0.523	0.27
564_L	624_K	0.523	0.27
576_Y	583_R	0.522	0.27
92_K	619_K	0.522	0.27
849_Y	857_L	0.522	0.27
726_I	758_V	0.522	0.27
707_K	794_A	0.522	0.27
77_I	184_E	0.520	0.27
590_D	608_A	0.520	0.27
131_E	275_N	0.519	0.27
253_F	323_A	0.519	0.27
494_M	548_M	0.518	0.27
151_K	488_D	0.518	0.27
255_G	359_V	0.518	0.27
495_E	656_L	0.518	0.27
170_Q	493_F	0.518	0.27
256_C	338_V	0.517	0.27
360_I	383_N	0.517	0.27
19_D	833_H	0.516	0.27
28_E	520_Y	0.516	0.27
177_W	464_T	0.516	0.27
663_V	672_R	0.515	0.27
214_D	448_D	0.515	0.27
493_F	518_A	0.515	0.27
136_E	544_F	0.515	0.27
572_D	594_E	0.514	0.26
89_A	170_Q	0.514	0.26
321_W	358_P	0.514	0.26
228_E	414_N	0.514	0.26
141_T	144_Y	0.514	0.26
480_G	485_R	0.514	0.26
547_L	571_A	0.514	0.26
810_V	853_K	0.513	0.26
272_A	293_A	0.513	0.26
38_L	524_V	0.513	0.26
39_S	59_G	0.512	0.26
129_T	813_K	0.512	0.26
535_I	660_E	0.512	0.26
195_I	498_W	0.512	0.26
244_T	845_R	0.512	0.26
134_R	447_D	0.512	0.26
227_S	248_T	0.511	0.26
176_C	582_E	0.511	0.26
100_W	491_D	0.511	0.26
348_F	352_Y	0.511	0.26
547_L	669_F	0.511	0.26
673_V	676_L	0.510	0.26
55_N	430_A	0.510	0.26
111_Q	629_D	0.510	0.26
172_I	175_C	0.510	0.26
243_L	322_A	0.509	0.26
197_A	848_I	0.508	0.26
119_Y	564_L	0.508	0.26
65_Y	71_K	0.508	0.26
485_R	488_D	0.508	0.26
330_Y	336_M	0.507	0.26
67_R	74_L	0.507	0.26
359_V	365_G	0.506	0.26
441_T	444_P	0.506	0.26
590_D	593_V	0.506	0.26
708_T	732_L	0.506	0.26
188_I	487_T	0.506	0.26
311_H	402_K	0.506	0.26
810_V	854_L	0.505	0.26
359_V	366_S	0.505	0.26
142_E	430_A	0.505	0.26
113_K	122_S	0.505	0.26
789_V	792_E	0.505	0.26
57_T	185_R	0.504	0.26
243_L	411_R	0.504	0.26
281_F	324_N	0.504	0.26
159_C	184_E	0.504	0.26
194_K	201_E	0.503	0.26
248_T	252_T	0.503	0.26
449_Q	478_V	0.503	0.26
55_N	526_I	0.503	0.26
491_D	495_E	0.503	0.26
56_Y	121_W	0.503	0.26
76_P	634_V	0.502	0.26
333_G	345_D	0.502	0.26
107_Y	654_M	0.502	0.26
136_E	176_C	0.502	0.26
341_H	361_L	0.501	0.26
252_T	344_R	0.501	0.26
347_E	359_V	0.501	0.26
765_T	769_C	0.501	0.26
696_E	700_A	0.500	0.26
115_L	139_F	0.500	0.26
422_V	847_V	0.500	0.26

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4arcA	1	0.9419	100	0.296	Contact Map
2v0cA	1	0.9128	100	0.303	Contact Map
3ziuA	1	0.6988	100	0.501	Contact Map
1ileA	1	0.807	100	0.585	Contact Map
1ffyA	1	0.8547	100	0.592	Contact Map
1gaxA	1	0.7953	100	0.6	Contact Map
1wz2A	1	0.836	100	0.604	Contact Map
1wkbA	1	0.7465	100	0.626	Contact Map
4qreA	1	0.5593	100	0.753	Contact Map
2x1lA	1	0.5605	100	0.756	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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