GLGB - ECOLI - GREMLIN Contacts

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GLGB - 1,4-alpha-glucan branching enzyme GlgB

UniProt:	P07762	Sequences: MSDRIDRDVINALIAGHFADPFSVLGMHKTTAGLEVRALLPDATDVWVIEPKTGRKLAKLECLDSRGFFSGVIPRRKNFFRYQLAVVWHGQQNLIDDPYRFGPLIQEMDAWLLSEGTHLRPYETLGAHADTMDGVTGTRFSVWAPNARRVSVVGQFNYWDGRRHPMRLRKESGIWELFIPGAHNGQLYKYEMIDANGNLRLKSDPYAFEAQMRPETASLICGLPEKVVQTEERKKANQFDAPISIYEVHLGSWRRHTDNNFWLSYRELADQLVPYAKWMGFTHLELLPINEHPFDGSWGYQPTGLYAPTRRFGTRDDFRYFIDAAHAAGLNVILDWVPGHFPTDDFALAEFDGTNLYEHSDPREGYHQDWNTLIYNYGRREVSNFLVGNALYWIERFGIDALRVDAVASMIYRDYSRKEGEWIPNEFGGRENLEAIEFLRNTNRILGEQVSGAVTMAEESTDFPGVSRPQDMGGLGFWYKWNLGWMHDTLDYMKLDPVYRQYHHDKLTFGILYNYTENFVLPLSHDEVVHGKKSILDRMPGDAWQKFANLRAYYGWMWAFPGKKLLFMGNEFAQGREWNHDASLDWHLLEGGDNWHHGVQRLVRDLNLTYRHHKAMHELDFDPYGFEWLVVDDKERSVLIFVRRDKEGNEIIVASNFTPVPRHDYRFGINQPGKWREILNTDSMHYHGSNAGNGGTVHSDEIASHGRQHSLSLTLPPLATIWLVREAE	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10378
Length:	728 (614)
Sequences:	3779 (2249)
Seq/√Len:	90.7

ECOLI - GLGB GLGX YGAQ
BACSU - GLGB PULA
SULSO - Q7LX99

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
605_D	686_Y	5.466	1.00
266_R	317_D	4.622	1.00
559_A	641_F	3.959	1.00
318_F	322_I	3.839	1.00
266_R	320_Y	3.741	1.00
254_R	271_Q	3.630	1.00
447_G	478_W	3.551	1.00
166_M	177_L	3.342	1.00
284_L	325_A	3.166	1.00
669_I	711_L	3.040	1.00
278_W	604_R	3.005	1.00
573_A	599_V	3.000	1.00
559_A	722_W	2.977	1.00
627_E	707_R	2.977	1.00
319_R	396_R	2.954	1.00
324_A	327_A	2.904	1.00
655_S	720_T	2.892	1.00
137_G	178_F	2.832	1.00
211_Q	215_E	2.820	1.00
120_R	123_E	2.776	1.00
230_T	233_R	2.755	1.00
392_Y	397_F	2.743	1.00
501_Q	635_E	2.712	1.00
153_V	201_L	2.690	1.00
343_T	366_Y	2.688	1.00
677_E	693_N	2.681	1.00
270_D	324_A	2.678	1.00
613_H	724_V	2.656	1.00
633_D	636_R	2.646	1.00
555_G	720_T	2.606	1.00
161_G	191_E	2.546	1.00
316_D	319_R	2.474	1.00
511_I	515_Y	2.457	1.00
523_L	570_N	2.442	1.00
666_R	710_S	2.430	1.00
418_K	421_E	2.424	1.00
206_Y	357_Y	2.423	1.00
138_T	182_A	2.405	1.00
579_N	582_A	2.400	1.00
699_S	709_H	2.370	1.00
277_K	328_A	2.352	1.00
286_L	321_F	2.352	1.00
274_P	328_A	2.340	1.00
559_A	653_V	2.337	1.00
245_I	520_V	2.318	1.00
510_G	560_F	2.289	1.00
155_Q	186_Q	2.286	1.00
627_E	644_R	2.255	1.00
317_D	320_Y	2.233	1.00
183_H	186_Q	2.224	1.00
248_V	276_A	2.201	1.00
286_L	289_I	2.196	1.00
542_D	545_Q	2.192	1.00
369_D	416_S	2.191	1.00
637_S	658_T	2.182	1.00
318_F	399_I	2.176	1.00
446_L	453_A	2.167	1.00
383_S	441_N	2.150	1.00
638_V	715_L	2.150	1.00
182_A	186_Q	2.086	1.00
713_L	723_L	2.055	1.00
602_L	681_T	2.050	1.00
323_D	327_A	2.033	1.00
321_F	325_A	2.031	1.00
194_D	200_R	2.027	1.00
629_L	652_I	2.014	1.00
306_Y	389_N	2.005	1.00
320_Y	324_A	1.998	1.00
290_N	389_N	1.984	1.00
276_A	284_L	1.965	1.00
427_F	433_L	1.950	1.00
243_I	454_V	1.937	1.00
191_E	201_L	1.933	1.00
308_P	392_Y	1.923	1.00
229_Q	233_R	1.914	1.00
572_F	584_L	1.904	1.00
273_V	328_A	1.879	1.00
444_R	470_Q	1.872	1.00
574_Q	578_W	1.865	1.00
276_A	330_L	1.857	1.00
131_T	136_T	1.847	1.00
676_R	724_V	1.842	1.00
314_T	317_D	1.838	1.00
535_I	554_Y	1.835	1.00
210_A	307_A	1.831	1.00
324_A	328_A	1.815	1.00
364_E	413_R	1.813	1.00
543_A	575_G	1.808	1.00
666_R	700_D	1.799	1.00
583_S	587_H	1.783	1.00
250_L	268_L	1.755	1.00
437_E	440_R	1.754	1.00
618_E	646_K	1.750	1.00
146_N	354_T	1.750	1.00
414_D	430_R	1.744	1.00
642_V	652_I	1.744	1.00
661_P	691_A	1.744	1.00
605_D	685_H	1.738	1.00
121_P	206_Y	1.731	1.00
664_D	712_S	1.720	1.00
213_R	295_D	1.720	1.00
120_R	449_Q	1.711	1.00
702_I	710_S	1.709	1.00
276_A	280_G	1.709	1.00
442_T	455_T	1.696	1.00
363_R	423_I	1.696	1.00
378_G	434_E	1.694	1.00
507_L	639_L	1.689	1.00
489_T	553_Y	1.687	1.00
182_A	220_I	1.672	1.00
523_L	553_Y	1.668	1.00
308_P	318_F	1.665	1.00
645_D	649_N	1.660	1.00
674_K	696_T	1.650	1.00
138_T	220_I	1.648	1.00
487_H	491_D	1.648	1.00
651_I	722_W	1.646	1.00
491_D	506_K	1.635	1.00
269_A	320_Y	1.632	1.00
609_T	679_L	1.631	1.00
575_G	578_W	1.612	1.00
209_E	221_C	1.611	1.00
155_Q	187_L	1.589	1.00
677_E	723_L	1.589	1.00
203_S	210_A	1.588	1.00
649_N	724_V	1.573	1.00
128_H	208_F	1.573	1.00
533_K	537_D	1.570	1.00
227_V	323_D	1.567	1.00
663_H	714_T	1.556	1.00
208_F	223_L	1.545	1.00
609_T	678_I	1.540	1.00
630_V	633_D	1.523	1.00
273_V	324_A	1.508	1.00
602_L	679_L	1.505	1.00
645_D	648_G	1.503	1.00
566_L	570_N	1.502	1.00
225_E	316_D	1.496	1.00
349_A	373_L	1.484	1.00
703_A	710_S	1.478	1.00
495_L	499_Y	1.467	1.00
666_R	712_S	1.466	1.00
264_S	267_E	1.461	1.00
443_N	455_T	1.454	0.99
109_D	118_H	1.452	0.99
291_E	309_T	1.449	0.99
261_F	267_E	1.443	0.99
364_E	423_I	1.443	0.99
608_L	612_H	1.434	0.99
692_G	695_G	1.434	0.99
256_H	259_N	1.429	0.99
186_Q	220_I	1.419	0.99
410_M	435_A	1.418	0.99
395_E	449_Q	1.410	0.99
194_D	198_N	1.406	0.99
229_Q	232_E	1.403	0.99
289_I	318_F	1.390	0.99
270_D	320_Y	1.385	0.99
576_R	585_D	1.384	0.99
495_L	506_K	1.380	0.99
149_R	193_I	1.370	0.99
256_H	261_F	1.367	0.99
279_M	600_Q	1.364	0.99
273_V	325_A	1.360	0.99
152_V	179_I	1.354	0.99
367_H	374_I	1.354	0.99
582_A	585_D	1.353	0.99
270_D	274_P	1.351	0.99
444_R	471_D	1.346	0.99
157_N	164_H	1.340	0.99
110_A	174_I	1.339	0.99
394_I	446_L	1.336	0.99
672_P	699_S	1.334	0.99
640_I	654_A	1.333	0.99
384_N	388_G	1.328	0.99
601_R	604_R	1.326	0.99
148_R	195_A	1.317	0.99
555_G	681_T	1.315	0.99
138_T	183_H	1.310	0.99
305_L	375_Y	1.305	0.99
700_D	710_S	1.304	0.99
229_Q	398_G	1.304	0.99
697_V	711_L	1.298	0.99
669_I	675_W	1.298	0.99
123_E	396_R	1.298	0.99
117_T	441_N	1.292	0.99
333_I	456_M	1.290	0.99
394_I	453_A	1.278	0.99
187_L	217_A	1.278	0.99
219_L	222_G	1.276	0.99
290_N	302_P	1.274	0.99
289_I	334_L	1.273	0.99
184_N	222_G	1.271	0.99
125_L	174_I	1.270	0.99
149_R	165_P	1.269	0.99
392_Y	396_R	1.264	0.99
684_M	690_N	1.248	0.98
193_I	199_L	1.244	0.98
653_V	722_W	1.242	0.98
685_H	690_N	1.231	0.98
543_A	595_W	1.230	0.98
151_S	191_E	1.228	0.98
223_L	319_R	1.225	0.98
666_R	702_I	1.224	0.98
543_A	546_K	1.219	0.98
151_S	193_I	1.212	0.98
127_A	190_Y	1.211	0.98
642_V	650_E	1.211	0.98
256_H	263_L	1.211	0.98
597_H	601_R	1.203	0.98
244_S	558_W	1.200	0.98
672_P	709_H	1.199	0.98
191_E	199_L	1.197	0.98
265_Y	308_P	1.185	0.98
654_A	713_L	1.182	0.98
141_S	176_E	1.179	0.98
237_N	240_D	1.177	0.98
359_H	376_N	1.177	0.98
493_M	657_F	1.175	0.98
148_R	193_I	1.175	0.98
716_P	719_A	1.174	0.98
142_V	351_F	1.171	0.98
256_H	267_E	1.170	0.98
395_E	450_V	1.169	0.98
210_A	304_G	1.169	0.98
227_V	231_E	1.168	0.98
111_W	115_E	1.162	0.97
164_H	177_L	1.153	0.97
124_T	139_R	1.151	0.97
130_D	139_R	1.149	0.97
630_V	640_I	1.147	0.97
673_G	699_S	1.146	0.97
296_G	580_H	1.146	0.97
150_V	192_M	1.143	0.97
283_H	331_N	1.141	0.97
108_M	111_W	1.139	0.97
250_L	265_Y	1.138	0.97
359_H	364_E	1.134	0.97
243_I	283_H	1.131	0.97
552_A	720_T	1.129	0.97
613_H	651_I	1.129	0.97
630_V	705_H	1.128	0.97
251_G	312_F	1.128	0.97
260_N	583_S	1.124	0.97
555_G	655_S	1.124	0.97
387_V	442_T	1.119	0.97
609_T	722_W	1.116	0.97
446_L	455_T	1.115	0.97
496_D	499_Y	1.112	0.97
263_L	271_Q	1.111	0.97
240_D	646_K	1.111	0.97
207_A	210_A	1.102	0.97
376_N	379_R	1.101	0.97
552_A	655_S	1.098	0.96
129_A	138_T	1.096	0.96
360_S	364_E	1.095	0.96
148_R	197_G	1.091	0.96
125_L	141_S	1.088	0.96
536_L	573_A	1.088	0.96
350_E	355_N	1.087	0.96
226_K	323_D	1.086	0.96
677_E	680_N	1.086	0.96
121_P	388_G	1.086	0.96
266_R	269_A	1.079	0.96
290_N	399_I	1.079	0.96
366_Y	371_N	1.078	0.96
677_E	695_G	1.077	0.96
278_W	600_Q	1.075	0.96
387_V	445_I	1.074	0.96
505_D	634_K	1.073	0.96
143_W	381_E	1.073	0.96
291_E	310_R	1.072	0.96
554_Y	603_V	1.071	0.96
250_L	286_L	1.070	0.96
601_R	605_D	1.068	0.96
390_A	402_L	1.065	0.96
368_Q	421_E	1.061	0.96
683_S	692_G	1.060	0.96
491_D	494_K	1.059	0.96
700_D	712_S	1.057	0.96
227_V	230_T	1.054	0.96
539_M	549_N	1.054	0.96
668_G	710_S	1.054	0.96
683_S	690_N	1.052	0.95
230_T	234_K	1.051	0.95
232_E	236_A	1.051	0.95
652_I	669_I	1.045	0.95
164_H	179_I	1.043	0.95
479_Y	621_F	1.042	0.95
494_K	533_K	1.039	0.95
129_A	184_N	1.038	0.95
465_G	468_R	1.037	0.95
555_G	602_L	1.036	0.95
654_A	667_F	1.034	0.95
231_E	234_K	1.026	0.95
426_E	434_E	1.020	0.95
544_W	661_P	1.018	0.95
426_E	437_E	1.016	0.95
355_N	360_S	1.015	0.94
554_Y	566_L	1.013	0.94
601_R	685_H	1.012	0.94
609_T	613_H	1.011	0.94
213_R	262_W	1.007	0.94
668_G	705_H	1.007	0.94
256_H	583_S	1.004	0.94
678_I	724_V	1.004	0.94
256_H	260_N	1.004	0.94
383_S	437_E	1.003	0.94
689_S	717_P	1.002	0.94
296_G	581_D	0.999	0.94
604_R	608_L	0.998	0.94
436_I	463_F	0.997	0.94
281_F	571_E	0.994	0.94
563_K	620_D	0.993	0.94
619_L	622_D	0.992	0.94
553_Y	556_W	0.992	0.94
118_H	121_P	0.991	0.94
666_R	704_S	0.991	0.94
629_L	668_G	0.989	0.94
546_K	575_G	0.989	0.94
691_A	719_A	0.986	0.94
664_D	714_T	0.984	0.94
269_A	324_A	0.984	0.94
162_R	191_E	0.983	0.93
597_H	600_Q	0.982	0.93
523_L	535_I	0.982	0.93
454_V	478_W	0.982	0.93
208_F	397_F	0.979	0.93
364_E	426_E	0.978	0.93
677_E	683_S	0.978	0.93
212_M	310_R	0.977	0.93
661_P	719_A	0.973	0.93
119_L	387_V	0.972	0.93
391_L	450_V	0.970	0.93
179_I	182_A	0.960	0.93
248_V	272_L	0.959	0.93
641_F	655_S	0.959	0.93
274_P	277_K	0.952	0.92
654_A	721_I	0.952	0.92
222_G	225_E	0.951	0.92
160_D	163_R	0.951	0.92
493_M	553_Y	0.951	0.92
270_D	273_V	0.948	0.92
254_R	263_L	0.948	0.92
559_A	655_S	0.945	0.92
515_Y	623_P	0.945	0.92
468_R	472_M	0.941	0.92
308_P	393_W	0.941	0.92
674_K	698_H	0.941	0.92
465_G	472_M	0.940	0.92
549_N	718_L	0.939	0.92
644_R	650_E	0.937	0.92
619_L	646_K	0.934	0.92
276_A	325_A	0.932	0.92
585_D	588_L	0.931	0.92
147_A	352_D	0.927	0.91
652_I	711_L	0.923	0.91
492_Y	504_H	0.921	0.91
127_A	138_T	0.913	0.91
244_S	607_N	0.911	0.91
184_N	221_C	0.911	0.91
478_W	518_N	0.911	0.91
431_E	436_I	0.910	0.91
238_Q	479_Y	0.909	0.91
209_E	310_R	0.907	0.90
581_D	585_D	0.905	0.90
411_I	436_I	0.904	0.90
334_L	399_I	0.904	0.90
200_R	345_D	0.903	0.90
185_G	219_L	0.903	0.90
250_L	273_V	0.903	0.90
437_E	441_N	0.900	0.90
306_Y	388_G	0.900	0.90
268_L	321_F	0.895	0.90
167_R	176_E	0.893	0.90
537_D	546_K	0.891	0.90
591_G	596_H	0.890	0.90
374_I	409_S	0.882	0.89
290_N	334_L	0.882	0.89
510_G	556_W	0.881	0.89
104_L	139_R	0.881	0.89
239_F	518_N	0.880	0.89
594_N	598_G	0.879	0.89
520_V	564_K	0.877	0.89
274_P	324_A	0.877	0.89
223_L	316_D	0.876	0.89
447_G	454_V	0.869	0.88
536_L	547_F	0.868	0.88
544_W	719_A	0.867	0.88
301_Q	372_T	0.867	0.88
704_S	707_R	0.865	0.88
291_E	311_R	0.863	0.88
654_A	723_L	0.862	0.88
367_H	409_S	0.862	0.88
248_V	286_L	0.862	0.88
469_P	472_M	0.860	0.88
499_Y	502_Y	0.860	0.88
544_W	689_S	0.859	0.88
523_L	554_Y	0.856	0.88
535_I	570_N	0.854	0.88
106_Q	109_D	0.851	0.87
536_L	575_G	0.851	0.87
111_W	114_S	0.850	0.87
124_T	141_S	0.848	0.87
125_L	206_Y	0.847	0.87
218_S	222_G	0.846	0.87
668_G	708_Q	0.846	0.87
636_R	662_R	0.842	0.87
152_V	177_L	0.840	0.87
364_E	376_N	0.837	0.87
318_F	321_F	0.834	0.86
359_H	365_G	0.834	0.86
255_R	583_S	0.833	0.86
187_L	211_Q	0.831	0.86
658_T	662_R	0.831	0.86
274_P	325_A	0.829	0.86
682_D	690_N	0.828	0.86
153_V	191_E	0.826	0.86
221_C	316_D	0.825	0.86
699_S	708_Q	0.822	0.86
302_P	305_L	0.821	0.85
699_S	711_L	0.821	0.85
154_G	159_W	0.820	0.85
284_L	321_F	0.820	0.85
619_L	624_Y	0.820	0.85
440_R	444_R	0.817	0.85
652_I	675_W	0.816	0.85
487_H	715_L	0.815	0.85
605_D	608_L	0.815	0.85
543_A	591_G	0.814	0.85
302_P	389_N	0.811	0.85
638_V	665_Y	0.811	0.85
394_I	402_L	0.809	0.85
441_N	444_R	0.807	0.84
280_G	608_L	0.806	0.84
208_F	392_Y	0.806	0.84
364_E	434_E	0.804	0.84
550_L	554_Y	0.803	0.84
149_R	191_E	0.802	0.84
498_V	502_Y	0.802	0.84
355_N	376_N	0.800	0.84
438_F	442_T	0.800	0.84
380_R	383_S	0.800	0.84
576_R	582_A	0.799	0.84
211_Q	217_A	0.797	0.84
103_P	167_R	0.796	0.84
590_E	597_H	0.796	0.84
273_V	321_F	0.795	0.84
468_R	518_N	0.793	0.83
256_H	271_Q	0.792	0.83
600_Q	604_R	0.790	0.83
319_R	397_F	0.789	0.83
279_M	604_R	0.788	0.83
405_D	526_D	0.786	0.83
615_A	651_I	0.783	0.83
515_Y	619_L	0.783	0.83
144_A	147_A	0.782	0.83
114_S	170_K	0.781	0.82
275_Y	279_M	0.781	0.82
367_H	377_Y	0.781	0.82
629_L	642_V	0.779	0.82
636_R	665_Y	0.776	0.82
493_M	549_N	0.775	0.82
139_R	176_E	0.775	0.82
305_L	385_F	0.774	0.82
112_L	115_E	0.773	0.82
705_H	710_S	0.772	0.82
447_G	518_N	0.770	0.82
218_S	223_L	0.770	0.82
495_L	503_H	0.770	0.82
703_A	708_Q	0.769	0.81
343_T	371_N	0.769	0.81
152_V	182_A	0.769	0.81
523_L	550_L	0.768	0.81
672_P	675_W	0.768	0.81
187_L	219_L	0.766	0.81
228_V	232_E	0.765	0.81
119_L	449_Q	0.762	0.81
589_L	600_Q	0.762	0.81
264_S	317_D	0.761	0.81
250_L	274_P	0.761	0.81
275_Y	600_Q	0.761	0.81
445_I	448_E	0.760	0.81
169_R	172_S	0.758	0.81
294_F	580_H	0.755	0.80
151_S	161_G	0.755	0.80
160_D	164_H	0.754	0.80
683_S	693_N	0.752	0.80
501_Q	658_T	0.752	0.80
559_A	609_T	0.751	0.80
108_M	112_L	0.751	0.80
230_T	398_G	0.750	0.80
466_V	475_L	0.746	0.80
598_G	602_L	0.744	0.79
668_G	707_R	0.744	0.79
491_D	495_L	0.743	0.79
359_H	434_E	0.740	0.79
389_N	392_Y	0.738	0.79
354_T	376_N	0.737	0.79
365_G	376_N	0.737	0.79
677_E	692_G	0.737	0.79
248_V	325_A	0.736	0.79
493_M	539_M	0.736	0.79
547_F	595_W	0.735	0.78
359_H	374_I	0.735	0.78
591_G	595_W	0.734	0.78
135_V	180_P	0.733	0.78
537_D	575_G	0.731	0.78
591_G	594_N	0.730	0.78
208_F	396_R	0.730	0.78
691_A	714_T	0.729	0.78
599_V	602_L	0.728	0.78
190_Y	206_Y	0.727	0.78
678_I	721_I	0.726	0.78
620_D	625_G	0.725	0.78
681_T	720_T	0.724	0.77
394_I	450_V	0.723	0.77
680_N	693_N	0.723	0.77
586_W	589_L	0.722	0.77
698_H	701_E	0.722	0.77
602_L	606_L	0.722	0.77
632_D	704_S	0.722	0.77
693_N	714_T	0.719	0.77
594_N	597_H	0.719	0.77
701_E	709_H	0.719	0.77
439_L	477_F	0.719	0.77
244_S	611_R	0.718	0.77
576_R	579_N	0.716	0.77
229_Q	234_K	0.713	0.76
209_E	315_R	0.712	0.76
259_N	262_W	0.711	0.76
587_H	590_E	0.711	0.76
203_S	218_S	0.710	0.76
140_F	190_Y	0.709	0.76
692_G	696_T	0.709	0.76
377_Y	435_A	0.708	0.76
209_E	219_L	0.708	0.76
319_R	392_Y	0.706	0.76
661_P	717_P	0.706	0.76
315_R	397_F	0.705	0.76
683_S	694_G	0.705	0.76
608_L	611_R	0.705	0.76
682_D	688_G	0.704	0.75
425_N	428_G	0.703	0.75
441_N	445_I	0.703	0.75
248_V	284_L	0.702	0.75
503_H	506_K	0.702	0.75
639_L	657_F	0.701	0.75
683_S	695_G	0.701	0.75
239_F	621_F	0.700	0.75
139_R	178_F	0.699	0.75
340_H	405_D	0.698	0.75
479_Y	520_V	0.697	0.75
550_L	573_A	0.697	0.75
206_Y	388_G	0.696	0.75
261_F	264_S	0.695	0.75
447_G	455_T	0.695	0.75
285_E	481_W	0.693	0.74
239_F	478_W	0.692	0.74
504_H	637_S	0.692	0.74
350_E	373_L	0.691	0.74
121_P	124_T	0.690	0.74
614_K	617_H	0.690	0.74
613_H	617_H	0.690	0.74
677_E	691_A	0.689	0.74
223_L	227_V	0.688	0.74
651_I	678_I	0.687	0.74
281_F	566_L	0.685	0.73
250_L	309_T	0.684	0.73
574_Q	577_E	0.684	0.73
652_I	723_L	0.684	0.73
668_G	706_G	0.683	0.73
631_V	639_L	0.683	0.73
248_V	268_L	0.682	0.73
403_R	526_D	0.681	0.73
694_G	697_V	0.681	0.73
356_L	359_H	0.680	0.73
495_L	502_Y	0.680	0.73
545_Q	718_L	0.679	0.73
303_T	347_A	0.679	0.73
447_G	471_D	0.678	0.73
244_S	281_F	0.677	0.73
636_R	705_H	0.677	0.73
146_N	352_D	0.677	0.73
408_A	460_S	0.676	0.72
661_P	714_T	0.674	0.72
141_S	174_I	0.674	0.72
391_L	445_I	0.673	0.72
156_F	159_W	0.670	0.72
230_T	323_D	0.668	0.72
390_A	442_T	0.668	0.72
707_R	710_S	0.666	0.71
447_G	453_A	0.666	0.71
641_F	722_W	0.665	0.71
641_F	653_V	0.663	0.71
277_K	611_R	0.661	0.71
654_A	715_L	0.661	0.71
135_V	178_F	0.661	0.71
225_E	319_R	0.660	0.71
534_S	537_D	0.660	0.71
662_R	714_T	0.660	0.71
493_M	507_L	0.660	0.71
504_H	508_T	0.659	0.71
423_I	426_E	0.655	0.70
232_E	329_G	0.655	0.70
446_L	450_V	0.654	0.70
112_L	117_T	0.653	0.70
207_A	303_T	0.652	0.70
268_L	325_A	0.652	0.70
163_R	191_E	0.651	0.70
129_A	136_T	0.650	0.70
640_I	667_F	0.649	0.69
295_D	309_T	0.649	0.69
625_G	628_W	0.649	0.69
278_W	589_L	0.649	0.69
350_E	360_S	0.648	0.69
601_R	686_Y	0.648	0.69
615_A	645_D	0.647	0.69
289_I	321_F	0.647	0.69
198_N	345_D	0.647	0.69
690_N	693_N	0.646	0.69
668_G	704_S	0.645	0.69
130_D	178_F	0.645	0.69
114_S	172_S	0.644	0.69
161_G	199_L	0.642	0.69
120_R	395_E	0.642	0.69
574_Q	585_D	0.640	0.68
417_R	420_G	0.640	0.68
444_R	448_E	0.638	0.68
340_H	526_D	0.638	0.68
499_Y	503_H	0.638	0.68
151_S	165_P	0.637	0.68
558_W	607_N	0.637	0.68
209_E	314_T	0.637	0.68
365_G	374_I	0.636	0.68
489_T	493_M	0.636	0.68
198_N	350_E	0.635	0.68
336_W	390_A	0.633	0.68
122_Y	395_E	0.633	0.68
552_A	657_F	0.633	0.68
704_S	710_S	0.632	0.67
222_G	226_K	0.631	0.67
120_R	391_L	0.630	0.67
644_R	707_R	0.630	0.67
498_V	501_Q	0.630	0.67
576_R	587_H	0.630	0.67
316_D	396_R	0.630	0.67
264_S	268_L	0.629	0.67
545_Q	661_P	0.628	0.67
594_N	624_Y	0.625	0.67
436_I	440_R	0.625	0.67
151_S	163_R	0.624	0.66
651_I	724_V	0.624	0.66
284_L	330_L	0.624	0.66
223_L	226_K	0.623	0.66
677_E	721_I	0.623	0.66
619_L	623_P	0.623	0.66
167_R	177_L	0.622	0.66
114_S	384_N	0.621	0.66
544_W	682_D	0.620	0.66
391_L	395_E	0.620	0.66
588_L	596_H	0.619	0.66
338_P	389_N	0.619	0.66
221_C	315_R	0.619	0.66
690_N	717_P	0.618	0.66
547_F	596_H	0.618	0.66
548_A	551_R	0.618	0.66
713_L	721_I	0.617	0.66
494_K	538_R	0.612	0.65
553_Y	720_T	0.611	0.65
543_A	547_F	0.611	0.65
136_T	178_F	0.611	0.65
131_T	178_F	0.610	0.65
149_R	162_R	0.610	0.65
454_V	479_Y	0.610	0.65
151_S	164_H	0.610	0.65
281_F	558_W	0.609	0.65
537_D	576_R	0.607	0.64
306_Y	384_N	0.607	0.64
359_H	379_R	0.607	0.64
269_A	317_D	0.606	0.64
677_E	714_T	0.606	0.64
335_D	405_D	0.606	0.64
408_A	461_T	0.604	0.64
232_E	235_K	0.603	0.64
359_H	363_R	0.603	0.64
262_W	295_D	0.602	0.64
142_V	150_V	0.602	0.64
263_L	583_S	0.601	0.64
118_H	124_T	0.601	0.64
250_L	289_I	0.601	0.64
504_H	632_D	0.601	0.64
427_F	431_E	0.600	0.63
265_Y	321_F	0.600	0.63
325_A	330_L	0.600	0.63
471_D	478_W	0.600	0.63
234_K	327_A	0.599	0.63
295_D	312_F	0.599	0.63
220_I	223_L	0.599	0.63
574_Q	586_W	0.599	0.63
140_F	188_Y	0.599	0.63
195_A	354_T	0.598	0.63
148_R	194_D	0.598	0.63
517_E	520_V	0.597	0.63
274_P	278_W	0.596	0.63
540_P	549_N	0.594	0.63
581_D	584_L	0.594	0.63
318_F	397_F	0.594	0.63
368_Q	418_K	0.593	0.62
104_L	169_R	0.593	0.62
266_R	314_T	0.592	0.62
709_H	712_S	0.592	0.62
575_G	595_W	0.592	0.62
224_P	396_R	0.591	0.62
320_Y	323_D	0.591	0.62
278_W	601_R	0.591	0.62
701_E	708_Q	0.589	0.62
187_L	215_E	0.589	0.62
414_D	419_E	0.588	0.62
248_V	273_V	0.587	0.62
350_E	366_Y	0.586	0.62
411_I	463_F	0.585	0.61
680_N	683_S	0.584	0.61
663_H	691_A	0.584	0.61
662_R	715_L	0.582	0.61
279_M	571_E	0.582	0.61
555_G	722_W	0.580	0.61
512_L	631_V	0.580	0.61
535_I	538_R	0.580	0.61
263_L	267_E	0.580	0.61
112_L	118_H	0.580	0.61
522_P	553_Y	0.579	0.61
677_E	697_V	0.579	0.61
149_R	161_G	0.579	0.61
420_G	424_P	0.578	0.61
507_L	556_W	0.578	0.61
566_L	572_F	0.578	0.61
556_W	657_F	0.577	0.60
682_D	693_N	0.576	0.60
145_P	173_G	0.576	0.60
301_Q	406_A	0.576	0.60
234_K	237_N	0.575	0.60
233_R	236_A	0.575	0.60
229_Q	237_N	0.575	0.60
314_T	318_F	0.574	0.60
228_V	231_E	0.574	0.60
339_G	372_T	0.574	0.60
268_L	273_V	0.574	0.60
572_F	585_D	0.573	0.60
547_F	599_V	0.573	0.60
233_R	237_N	0.572	0.60
279_M	603_V	0.571	0.60
693_N	697_V	0.571	0.60
266_R	270_D	0.571	0.60
450_V	453_A	0.571	0.60
287_L	292_H	0.570	0.59
426_E	433_L	0.570	0.59
110_A	114_S	0.570	0.59
127_A	208_F	0.570	0.59
248_V	253_W	0.570	0.59
184_N	224_P	0.569	0.59
554_Y	570_N	0.569	0.59
282_T	611_R	0.569	0.59
148_R	196_N	0.569	0.59
146_N	376_N	0.569	0.59
233_R	453_A	0.567	0.59
124_T	319_R	0.567	0.59
161_G	201_L	0.567	0.59
566_L	603_V	0.566	0.59
140_F	204_D	0.565	0.59
339_G	368_Q	0.565	0.59
584_L	588_L	0.565	0.59
121_P	384_N	0.565	0.59
467_S	519_F	0.564	0.59
213_R	310_R	0.564	0.59
196_N	200_R	0.564	0.59
587_H	591_G	0.564	0.59
471_D	518_N	0.563	0.59
544_W	717_P	0.562	0.58
277_K	649_N	0.561	0.58
482_N	510_G	0.560	0.58
113_L	116_G	0.560	0.58
281_F	603_V	0.559	0.58
242_P	617_H	0.559	0.58
239_F	447_G	0.559	0.58
682_D	717_P	0.558	0.58
501_Q	634_K	0.558	0.58
273_V	284_L	0.558	0.58
143_W	382_V	0.557	0.58
708_Q	711_L	0.557	0.58
109_D	112_L	0.557	0.58
702_I	712_S	0.557	0.58
545_Q	549_N	0.556	0.58
245_I	479_Y	0.556	0.58
214_P	217_A	0.555	0.57
534_S	538_R	0.555	0.57
545_Q	689_S	0.554	0.57
613_H	649_N	0.554	0.57
219_L	223_L	0.552	0.57
210_A	310_R	0.552	0.57
703_A	709_H	0.552	0.57
413_R	433_L	0.551	0.57
252_S	461_T	0.551	0.57
413_R	435_A	0.551	0.57
578_W	584_L	0.550	0.57
108_M	114_S	0.550	0.57
144_A	352_D	0.548	0.57
236_A	241_A	0.548	0.57
380_R	384_N	0.548	0.57
555_G	719_A	0.548	0.57
552_A	719_A	0.548	0.57
157_N	160_D	0.547	0.56
231_E	323_D	0.547	0.56
682_D	689_S	0.546	0.56
522_P	535_I	0.545	0.56
471_D	632_D	0.545	0.56
665_Y	705_H	0.545	0.56
250_L	325_A	0.545	0.56
185_G	220_I	0.544	0.56
127_A	140_F	0.543	0.56
237_N	241_A	0.543	0.56
209_E	212_M	0.543	0.56
580_H	585_D	0.541	0.56
224_P	316_D	0.540	0.55
119_L	445_I	0.540	0.55
472_M	518_N	0.540	0.55
189_K	201_L	0.540	0.55
549_N	552_A	0.539	0.55
702_I	708_Q	0.539	0.55
188_Y	204_D	0.538	0.55
413_R	430_R	0.538	0.55
228_V	235_K	0.537	0.55
638_V	654_A	0.536	0.55
652_I	667_F	0.535	0.55
337_V	340_H	0.535	0.55
422_W	430_R	0.534	0.55
555_G	559_A	0.534	0.55
230_T	236_A	0.534	0.55
609_T	617_H	0.533	0.54
467_S	621_F	0.533	0.54
366_Y	373_L	0.533	0.54
627_E	642_V	0.532	0.54
462_D	487_H	0.532	0.54
187_L	190_Y	0.532	0.54
618_E	645_D	0.532	0.54
630_V	704_S	0.531	0.54
192_M	351_F	0.531	0.54
184_N	225_E	0.531	0.54
445_I	449_Q	0.530	0.54
130_D	137_G	0.529	0.54
302_P	343_T	0.529	0.54
697_V	700_D	0.528	0.54
428_G	431_E	0.528	0.54
255_R	587_H	0.528	0.54
377_Y	409_S	0.528	0.54
103_P	106_Q	0.528	0.54
453_A	478_W	0.527	0.54
413_R	434_E	0.527	0.54
633_D	665_Y	0.526	0.53
460_S	486_M	0.526	0.53
274_P	571_E	0.525	0.53
160_D	165_P	0.524	0.53
602_L	605_D	0.523	0.53
715_L	721_I	0.523	0.53
557_M	566_L	0.523	0.53
239_F	454_V	0.523	0.53
106_Q	118_H	0.522	0.53
348_L	351_F	0.521	0.53
137_G	181_G	0.521	0.53
629_L	640_I	0.520	0.53
130_D	136_T	0.520	0.53
642_V	670_N	0.519	0.53
115_E	118_H	0.519	0.53
365_G	423_I	0.518	0.52
619_L	648_G	0.518	0.52
489_T	507_L	0.518	0.52
238_Q	241_A	0.518	0.52
582_A	586_W	0.518	0.52
483_L	486_M	0.517	0.52
505_D	639_L	0.517	0.52
142_V	192_M	0.517	0.52
112_L	116_G	0.516	0.52
679_L	722_W	0.516	0.52
376_N	380_R	0.516	0.52
647_E	650_E	0.516	0.52
146_N	379_R	0.515	0.52
146_N	355_N	0.515	0.52
458_E	526_D	0.514	0.52
208_F	221_C	0.514	0.52
437_E	444_R	0.514	0.52
295_D	310_R	0.514	0.52
118_H	384_N	0.513	0.52
650_E	675_W	0.512	0.52
329_G	713_L	0.512	0.52
493_M	523_L	0.512	0.52
412_Y	461_T	0.512	0.52
537_D	543_A	0.511	0.51
119_L	441_N	0.511	0.51
210_A	218_S	0.511	0.51
109_D	121_P	0.511	0.51
151_S	199_L	0.510	0.51
233_R	238_Q	0.510	0.51
122_Y	128_H	0.510	0.51
486_M	527_E	0.509	0.51
579_N	583_S	0.509	0.51
253_W	275_Y	0.509	0.51
588_L	591_G	0.509	0.51
268_L	271_Q	0.509	0.51
704_S	711_L	0.508	0.51
188_Y	207_A	0.508	0.51
693_N	696_T	0.507	0.51
556_W	560_F	0.507	0.51
123_E	449_Q	0.507	0.51
107_E	110_A	0.507	0.51
511_I	514_N	0.506	0.51
249_H	292_H	0.506	0.51
458_E	525_H	0.504	0.50
535_I	550_L	0.503	0.50
294_F	301_Q	0.501	0.50
510_G	639_L	0.501	0.50
355_N	358_E	0.500	0.50

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3k1dA	1	0.9766	100	0.208	Contact Map
1m7xA	1	0.8146	100	0.353	Contact Map
3amlA	1	0.8654	100	0.365	Contact Map
4bzyA	1	0.8297	100	0.394	Contact Map
3wdhA	1	0.8585	100	0.468	Contact Map
2e8yA	1	0.864	100	0.482	Contact Map
1bf2A	1	0.8008	100	0.492	Contact Map
4j7rA	2	0.8269	100	0.493	Contact Map
2wanA	1	0.8942	100	0.497	Contact Map
3fawA	1	0.8887	100	0.511	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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