GREMLIN Database
GLGB - 1,4-alpha-glucan branching enzyme GlgB
UniProt: P07762 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG10378
Length: 728 (614)
Sequences: 3779 (2249)
Seq/√Len: 90.7

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
605_D686_Y5.4661.00
266_R317_D4.6221.00
559_A641_F3.9591.00
318_F322_I3.8391.00
266_R320_Y3.7411.00
254_R271_Q3.6301.00
447_G478_W3.5511.00
166_M177_L3.3421.00
284_L325_A3.1661.00
669_I711_L3.0401.00
278_W604_R3.0051.00
573_A599_V3.0001.00
559_A722_W2.9771.00
627_E707_R2.9771.00
319_R396_R2.9541.00
324_A327_A2.9041.00
655_S720_T2.8921.00
137_G178_F2.8321.00
211_Q215_E2.8201.00
120_R123_E2.7761.00
230_T233_R2.7551.00
392_Y397_F2.7431.00
501_Q635_E2.7121.00
153_V201_L2.6901.00
343_T366_Y2.6881.00
677_E693_N2.6811.00
270_D324_A2.6781.00
613_H724_V2.6561.00
633_D636_R2.6461.00
555_G720_T2.6061.00
161_G191_E2.5461.00
316_D319_R2.4741.00
511_I515_Y2.4571.00
523_L570_N2.4421.00
666_R710_S2.4301.00
418_K421_E2.4241.00
206_Y357_Y2.4231.00
138_T182_A2.4051.00
579_N582_A2.4001.00
699_S709_H2.3701.00
277_K328_A2.3521.00
286_L321_F2.3521.00
274_P328_A2.3401.00
559_A653_V2.3371.00
245_I520_V2.3181.00
510_G560_F2.2891.00
155_Q186_Q2.2861.00
627_E644_R2.2551.00
317_D320_Y2.2331.00
183_H186_Q2.2241.00
248_V276_A2.2011.00
286_L289_I2.1961.00
542_D545_Q2.1921.00
369_D416_S2.1911.00
637_S658_T2.1821.00
318_F399_I2.1761.00
446_L453_A2.1671.00
383_S441_N2.1501.00
638_V715_L2.1501.00
182_A186_Q2.0861.00
713_L723_L2.0551.00
602_L681_T2.0501.00
323_D327_A2.0331.00
321_F325_A2.0311.00
194_D200_R2.0271.00
629_L652_I2.0141.00
306_Y389_N2.0051.00
320_Y324_A1.9981.00
290_N389_N1.9841.00
276_A284_L1.9651.00
427_F433_L1.9501.00
243_I454_V1.9371.00
191_E201_L1.9331.00
308_P392_Y1.9231.00
229_Q233_R1.9141.00
572_F584_L1.9041.00
273_V328_A1.8791.00
444_R470_Q1.8721.00
574_Q578_W1.8651.00
276_A330_L1.8571.00
131_T136_T1.8471.00
676_R724_V1.8421.00
314_T317_D1.8381.00
535_I554_Y1.8351.00
210_A307_A1.8311.00
324_A328_A1.8151.00
364_E413_R1.8131.00
543_A575_G1.8081.00
666_R700_D1.7991.00
583_S587_H1.7831.00
250_L268_L1.7551.00
437_E440_R1.7541.00
618_E646_K1.7501.00
146_N354_T1.7501.00
414_D430_R1.7441.00
642_V652_I1.7441.00
661_P691_A1.7441.00
605_D685_H1.7381.00
121_P206_Y1.7311.00
664_D712_S1.7201.00
213_R295_D1.7201.00
120_R449_Q1.7111.00
702_I710_S1.7091.00
276_A280_G1.7091.00
442_T455_T1.6961.00
363_R423_I1.6961.00
378_G434_E1.6941.00
507_L639_L1.6891.00
489_T553_Y1.6871.00
182_A220_I1.6721.00
523_L553_Y1.6681.00
308_P318_F1.6651.00
645_D649_N1.6601.00
674_K696_T1.6501.00
138_T220_I1.6481.00
487_H491_D1.6481.00
651_I722_W1.6461.00
491_D506_K1.6351.00
269_A320_Y1.6321.00
609_T679_L1.6311.00
575_G578_W1.6121.00
209_E221_C1.6111.00
155_Q187_L1.5891.00
677_E723_L1.5891.00
203_S210_A1.5881.00
649_N724_V1.5731.00
128_H208_F1.5731.00
533_K537_D1.5701.00
227_V323_D1.5671.00
663_H714_T1.5561.00
208_F223_L1.5451.00
609_T678_I1.5401.00
630_V633_D1.5231.00
273_V324_A1.5081.00
602_L679_L1.5051.00
645_D648_G1.5031.00
566_L570_N1.5021.00
225_E316_D1.4961.00
349_A373_L1.4841.00
703_A710_S1.4781.00
495_L499_Y1.4671.00
666_R712_S1.4661.00
264_S267_E1.4611.00
443_N455_T1.4540.99
109_D118_H1.4520.99
291_E309_T1.4490.99
261_F267_E1.4430.99
364_E423_I1.4430.99
608_L612_H1.4340.99
692_G695_G1.4340.99
256_H259_N1.4290.99
186_Q220_I1.4190.99
410_M435_A1.4180.99
395_E449_Q1.4100.99
194_D198_N1.4060.99
229_Q232_E1.4030.99
289_I318_F1.3900.99
270_D320_Y1.3850.99
576_R585_D1.3840.99
495_L506_K1.3800.99
149_R193_I1.3700.99
256_H261_F1.3670.99
279_M600_Q1.3640.99
273_V325_A1.3600.99
152_V179_I1.3540.99
367_H374_I1.3540.99
582_A585_D1.3530.99
270_D274_P1.3510.99
444_R471_D1.3460.99
157_N164_H1.3400.99
110_A174_I1.3390.99
394_I446_L1.3360.99
672_P699_S1.3340.99
640_I654_A1.3330.99
384_N388_G1.3280.99
601_R604_R1.3260.99
148_R195_A1.3170.99
555_G681_T1.3150.99
138_T183_H1.3100.99
305_L375_Y1.3050.99
700_D710_S1.3040.99
229_Q398_G1.3040.99
697_V711_L1.2980.99
669_I675_W1.2980.99
123_E396_R1.2980.99
117_T441_N1.2920.99
333_I456_M1.2900.99
394_I453_A1.2780.99
187_L217_A1.2780.99
219_L222_G1.2760.99
290_N302_P1.2740.99
289_I334_L1.2730.99
184_N222_G1.2710.99
125_L174_I1.2700.99
149_R165_P1.2690.99
392_Y396_R1.2640.99
684_M690_N1.2480.98
193_I199_L1.2440.98
653_V722_W1.2420.98
685_H690_N1.2310.98
543_A595_W1.2300.98
151_S191_E1.2280.98
223_L319_R1.2250.98
666_R702_I1.2240.98
543_A546_K1.2190.98
151_S193_I1.2120.98
127_A190_Y1.2110.98
642_V650_E1.2110.98
256_H263_L1.2110.98
597_H601_R1.2030.98
244_S558_W1.2000.98
672_P709_H1.1990.98
191_E199_L1.1970.98
265_Y308_P1.1850.98
654_A713_L1.1820.98
141_S176_E1.1790.98
237_N240_D1.1770.98
359_H376_N1.1770.98
493_M657_F1.1750.98
148_R193_I1.1750.98
716_P719_A1.1740.98
142_V351_F1.1710.98
256_H267_E1.1700.98
395_E450_V1.1690.98
210_A304_G1.1690.98
227_V231_E1.1680.98
111_W115_E1.1620.97
164_H177_L1.1530.97
124_T139_R1.1510.97
130_D139_R1.1490.97
630_V640_I1.1470.97
673_G699_S1.1460.97
296_G580_H1.1460.97
150_V192_M1.1430.97
283_H331_N1.1410.97
108_M111_W1.1390.97
250_L265_Y1.1380.97
359_H364_E1.1340.97
243_I283_H1.1310.97
552_A720_T1.1290.97
613_H651_I1.1290.97
630_V705_H1.1280.97
251_G312_F1.1280.97
260_N583_S1.1240.97
555_G655_S1.1240.97
387_V442_T1.1190.97
609_T722_W1.1160.97
446_L455_T1.1150.97
496_D499_Y1.1120.97
263_L271_Q1.1110.97
240_D646_K1.1110.97
207_A210_A1.1020.97
376_N379_R1.1010.97
552_A655_S1.0980.96
129_A138_T1.0960.96
360_S364_E1.0950.96
148_R197_G1.0910.96
125_L141_S1.0880.96
536_L573_A1.0880.96
350_E355_N1.0870.96
226_K323_D1.0860.96
677_E680_N1.0860.96
121_P388_G1.0860.96
266_R269_A1.0790.96
290_N399_I1.0790.96
366_Y371_N1.0780.96
677_E695_G1.0770.96
278_W600_Q1.0750.96
387_V445_I1.0740.96
505_D634_K1.0730.96
143_W381_E1.0730.96
291_E310_R1.0720.96
554_Y603_V1.0710.96
250_L286_L1.0700.96
601_R605_D1.0680.96
390_A402_L1.0650.96
368_Q421_E1.0610.96
683_S692_G1.0600.96
491_D494_K1.0590.96
700_D712_S1.0570.96
227_V230_T1.0540.96
539_M549_N1.0540.96
668_G710_S1.0540.96
683_S690_N1.0520.95
230_T234_K1.0510.95
232_E236_A1.0510.95
652_I669_I1.0450.95
164_H179_I1.0430.95
479_Y621_F1.0420.95
494_K533_K1.0390.95
129_A184_N1.0380.95
465_G468_R1.0370.95
555_G602_L1.0360.95
654_A667_F1.0340.95
231_E234_K1.0260.95
426_E434_E1.0200.95
544_W661_P1.0180.95
426_E437_E1.0160.95
355_N360_S1.0150.94
554_Y566_L1.0130.94
601_R685_H1.0120.94
609_T613_H1.0110.94
213_R262_W1.0070.94
668_G705_H1.0070.94
256_H583_S1.0040.94
678_I724_V1.0040.94
256_H260_N1.0040.94
383_S437_E1.0030.94
689_S717_P1.0020.94
296_G581_D0.9990.94
604_R608_L0.9980.94
436_I463_F0.9970.94
281_F571_E0.9940.94
563_K620_D0.9930.94
619_L622_D0.9920.94
553_Y556_W0.9920.94
118_H121_P0.9910.94
666_R704_S0.9910.94
629_L668_G0.9890.94
546_K575_G0.9890.94
691_A719_A0.9860.94
664_D714_T0.9840.94
269_A324_A0.9840.94
162_R191_E0.9830.93
597_H600_Q0.9820.93
523_L535_I0.9820.93
454_V478_W0.9820.93
208_F397_F0.9790.93
364_E426_E0.9780.93
677_E683_S0.9780.93
212_M310_R0.9770.93
661_P719_A0.9730.93
119_L387_V0.9720.93
391_L450_V0.9700.93
179_I182_A0.9600.93
248_V272_L0.9590.93
641_F655_S0.9590.93
274_P277_K0.9520.92
654_A721_I0.9520.92
222_G225_E0.9510.92
160_D163_R0.9510.92
493_M553_Y0.9510.92
270_D273_V0.9480.92
254_R263_L0.9480.92
559_A655_S0.9450.92
515_Y623_P0.9450.92
468_R472_M0.9410.92
308_P393_W0.9410.92
674_K698_H0.9410.92
465_G472_M0.9400.92
549_N718_L0.9390.92
644_R650_E0.9370.92
619_L646_K0.9340.92
276_A325_A0.9320.92
585_D588_L0.9310.92
147_A352_D0.9270.91
652_I711_L0.9230.91
492_Y504_H0.9210.91
127_A138_T0.9130.91
244_S607_N0.9110.91
184_N221_C0.9110.91
478_W518_N0.9110.91
431_E436_I0.9100.91
238_Q479_Y0.9090.91
209_E310_R0.9070.90
581_D585_D0.9050.90
411_I436_I0.9040.90
334_L399_I0.9040.90
200_R345_D0.9030.90
185_G219_L0.9030.90
250_L273_V0.9030.90
437_E441_N0.9000.90
306_Y388_G0.9000.90
268_L321_F0.8950.90
167_R176_E0.8930.90
537_D546_K0.8910.90
591_G596_H0.8900.90
374_I409_S0.8820.89
290_N334_L0.8820.89
510_G556_W0.8810.89
104_L139_R0.8810.89
239_F518_N0.8800.89
594_N598_G0.8790.89
520_V564_K0.8770.89
274_P324_A0.8770.89
223_L316_D0.8760.89
447_G454_V0.8690.88
536_L547_F0.8680.88
544_W719_A0.8670.88
301_Q372_T0.8670.88
704_S707_R0.8650.88
291_E311_R0.8630.88
654_A723_L0.8620.88
367_H409_S0.8620.88
248_V286_L0.8620.88
469_P472_M0.8600.88
499_Y502_Y0.8600.88
544_W689_S0.8590.88
523_L554_Y0.8560.88
535_I570_N0.8540.88
106_Q109_D0.8510.87
536_L575_G0.8510.87
111_W114_S0.8500.87
124_T141_S0.8480.87
125_L206_Y0.8470.87
218_S222_G0.8460.87
668_G708_Q0.8460.87
636_R662_R0.8420.87
152_V177_L0.8400.87
364_E376_N0.8370.87
318_F321_F0.8340.86
359_H365_G0.8340.86
255_R583_S0.8330.86
187_L211_Q0.8310.86
658_T662_R0.8310.86
274_P325_A0.8290.86
682_D690_N0.8280.86
153_V191_E0.8260.86
221_C316_D0.8250.86
699_S708_Q0.8220.86
302_P305_L0.8210.85
699_S711_L0.8210.85
154_G159_W0.8200.85
284_L321_F0.8200.85
619_L624_Y0.8200.85
440_R444_R0.8170.85
652_I675_W0.8160.85
487_H715_L0.8150.85
605_D608_L0.8150.85
543_A591_G0.8140.85
302_P389_N0.8110.85
638_V665_Y0.8110.85
394_I402_L0.8090.85
441_N444_R0.8070.84
280_G608_L0.8060.84
208_F392_Y0.8060.84
364_E434_E0.8040.84
550_L554_Y0.8030.84
149_R191_E0.8020.84
498_V502_Y0.8020.84
355_N376_N0.8000.84
438_F442_T0.8000.84
380_R383_S0.8000.84
576_R582_A0.7990.84
211_Q217_A0.7970.84
103_P167_R0.7960.84
590_E597_H0.7960.84
273_V321_F0.7950.84
468_R518_N0.7930.83
256_H271_Q0.7920.83
600_Q604_R0.7900.83
319_R397_F0.7890.83
279_M604_R0.7880.83
405_D526_D0.7860.83
615_A651_I0.7830.83
515_Y619_L0.7830.83
144_A147_A0.7820.83
114_S170_K0.7810.82
275_Y279_M0.7810.82
367_H377_Y0.7810.82
629_L642_V0.7790.82
636_R665_Y0.7760.82
493_M549_N0.7750.82
139_R176_E0.7750.82
305_L385_F0.7740.82
112_L115_E0.7730.82
705_H710_S0.7720.82
447_G518_N0.7700.82
218_S223_L0.7700.82
495_L503_H0.7700.82
703_A708_Q0.7690.81
343_T371_N0.7690.81
152_V182_A0.7690.81
523_L550_L0.7680.81
672_P675_W0.7680.81
187_L219_L0.7660.81
228_V232_E0.7650.81
119_L449_Q0.7620.81
589_L600_Q0.7620.81
264_S317_D0.7610.81
250_L274_P0.7610.81
275_Y600_Q0.7610.81
445_I448_E0.7600.81
169_R172_S0.7580.81
294_F580_H0.7550.80
151_S161_G0.7550.80
160_D164_H0.7540.80
683_S693_N0.7520.80
501_Q658_T0.7520.80
559_A609_T0.7510.80
108_M112_L0.7510.80
230_T398_G0.7500.80
466_V475_L0.7460.80
598_G602_L0.7440.79
668_G707_R0.7440.79
491_D495_L0.7430.79
359_H434_E0.7400.79
389_N392_Y0.7380.79
354_T376_N0.7370.79
365_G376_N0.7370.79
677_E692_G0.7370.79
248_V325_A0.7360.79
493_M539_M0.7360.79
547_F595_W0.7350.78
359_H374_I0.7350.78
591_G595_W0.7340.78
135_V180_P0.7330.78
537_D575_G0.7310.78
591_G594_N0.7300.78
208_F396_R0.7300.78
691_A714_T0.7290.78
599_V602_L0.7280.78
190_Y206_Y0.7270.78
678_I721_I0.7260.78
620_D625_G0.7250.78
681_T720_T0.7240.77
394_I450_V0.7230.77
680_N693_N0.7230.77
586_W589_L0.7220.77
698_H701_E0.7220.77
602_L606_L0.7220.77
632_D704_S0.7220.77
693_N714_T0.7190.77
594_N597_H0.7190.77
701_E709_H0.7190.77
439_L477_F0.7190.77
244_S611_R0.7180.77
576_R579_N0.7160.77
229_Q234_K0.7130.76
209_E315_R0.7120.76
259_N262_W0.7110.76
587_H590_E0.7110.76
203_S218_S0.7100.76
140_F190_Y0.7090.76
692_G696_T0.7090.76
377_Y435_A0.7080.76
209_E219_L0.7080.76
319_R392_Y0.7060.76
661_P717_P0.7060.76
315_R397_F0.7050.76
683_S694_G0.7050.76
608_L611_R0.7050.76
682_D688_G0.7040.75
425_N428_G0.7030.75
441_N445_I0.7030.75
248_V284_L0.7020.75
503_H506_K0.7020.75
639_L657_F0.7010.75
683_S695_G0.7010.75
239_F621_F0.7000.75
139_R178_F0.6990.75
340_H405_D0.6980.75
479_Y520_V0.6970.75
550_L573_A0.6970.75
206_Y388_G0.6960.75
261_F264_S0.6950.75
447_G455_T0.6950.75
285_E481_W0.6930.74
239_F478_W0.6920.74
504_H637_S0.6920.74
350_E373_L0.6910.74
121_P124_T0.6900.74
614_K617_H0.6900.74
613_H617_H0.6900.74
677_E691_A0.6890.74
223_L227_V0.6880.74
651_I678_I0.6870.74
281_F566_L0.6850.73
250_L309_T0.6840.73
574_Q577_E0.6840.73
652_I723_L0.6840.73
668_G706_G0.6830.73
631_V639_L0.6830.73
248_V268_L0.6820.73
403_R526_D0.6810.73
694_G697_V0.6810.73
356_L359_H0.6800.73
495_L502_Y0.6800.73
545_Q718_L0.6790.73
303_T347_A0.6790.73
447_G471_D0.6780.73
244_S281_F0.6770.73
636_R705_H0.6770.73
146_N352_D0.6770.73
408_A460_S0.6760.72
661_P714_T0.6740.72
141_S174_I0.6740.72
391_L445_I0.6730.72
156_F159_W0.6700.72
230_T323_D0.6680.72
390_A442_T0.6680.72
707_R710_S0.6660.71
447_G453_A0.6660.71
641_F722_W0.6650.71
641_F653_V0.6630.71
277_K611_R0.6610.71
654_A715_L0.6610.71
135_V178_F0.6610.71
225_E319_R0.6600.71
534_S537_D0.6600.71
662_R714_T0.6600.71
493_M507_L0.6600.71
504_H508_T0.6590.71
423_I426_E0.6550.70
232_E329_G0.6550.70
446_L450_V0.6540.70
112_L117_T0.6530.70
207_A303_T0.6520.70
268_L325_A0.6520.70
163_R191_E0.6510.70
129_A136_T0.6500.70
640_I667_F0.6490.69
295_D309_T0.6490.69
625_G628_W0.6490.69
278_W589_L0.6490.69
350_E360_S0.6480.69
601_R686_Y0.6480.69
615_A645_D0.6470.69
289_I321_F0.6470.69
198_N345_D0.6470.69
690_N693_N0.6460.69
668_G704_S0.6450.69
130_D178_F0.6450.69
114_S172_S0.6440.69
161_G199_L0.6420.69
120_R395_E0.6420.69
574_Q585_D0.6400.68
417_R420_G0.6400.68
444_R448_E0.6380.68
340_H526_D0.6380.68
499_Y503_H0.6380.68
151_S165_P0.6370.68
558_W607_N0.6370.68
209_E314_T0.6370.68
365_G374_I0.6360.68
489_T493_M0.6360.68
198_N350_E0.6350.68
336_W390_A0.6330.68
122_Y395_E0.6330.68
552_A657_F0.6330.68
704_S710_S0.6320.67
222_G226_K0.6310.67
120_R391_L0.6300.67
644_R707_R0.6300.67
498_V501_Q0.6300.67
576_R587_H0.6300.67
316_D396_R0.6300.67
264_S268_L0.6290.67
545_Q661_P0.6280.67
594_N624_Y0.6250.67
436_I440_R0.6250.67
151_S163_R0.6240.66
651_I724_V0.6240.66
284_L330_L0.6240.66
223_L226_K0.6230.66
677_E721_I0.6230.66
619_L623_P0.6230.66
167_R177_L0.6220.66
114_S384_N0.6210.66
544_W682_D0.6200.66
391_L395_E0.6200.66
588_L596_H0.6190.66
338_P389_N0.6190.66
221_C315_R0.6190.66
690_N717_P0.6180.66
547_F596_H0.6180.66
548_A551_R0.6180.66
713_L721_I0.6170.66
494_K538_R0.6120.65
553_Y720_T0.6110.65
543_A547_F0.6110.65
136_T178_F0.6110.65
131_T178_F0.6100.65
149_R162_R0.6100.65
454_V479_Y0.6100.65
151_S164_H0.6100.65
281_F558_W0.6090.65
537_D576_R0.6070.64
306_Y384_N0.6070.64
359_H379_R0.6070.64
269_A317_D0.6060.64
677_E714_T0.6060.64
335_D405_D0.6060.64
408_A461_T0.6040.64
232_E235_K0.6030.64
359_H363_R0.6030.64
262_W295_D0.6020.64
142_V150_V0.6020.64
263_L583_S0.6010.64
118_H124_T0.6010.64
250_L289_I0.6010.64
504_H632_D0.6010.64
427_F431_E0.6000.63
265_Y321_F0.6000.63
325_A330_L0.6000.63
471_D478_W0.6000.63
234_K327_A0.5990.63
295_D312_F0.5990.63
220_I223_L0.5990.63
574_Q586_W0.5990.63
140_F188_Y0.5990.63
195_A354_T0.5980.63
148_R194_D0.5980.63
517_E520_V0.5970.63
274_P278_W0.5960.63
540_P549_N0.5940.63
581_D584_L0.5940.63
318_F397_F0.5940.63
368_Q418_K0.5930.62
104_L169_R0.5930.62
266_R314_T0.5920.62
709_H712_S0.5920.62
575_G595_W0.5920.62
224_P396_R0.5910.62
320_Y323_D0.5910.62
278_W601_R0.5910.62
701_E708_Q0.5890.62
187_L215_E0.5890.62
414_D419_E0.5880.62
248_V273_V0.5870.62
350_E366_Y0.5860.62
411_I463_F0.5850.61
680_N683_S0.5840.61
663_H691_A0.5840.61
662_R715_L0.5820.61
279_M571_E0.5820.61
555_G722_W0.5800.61
512_L631_V0.5800.61
535_I538_R0.5800.61
263_L267_E0.5800.61
112_L118_H0.5800.61
522_P553_Y0.5790.61
677_E697_V0.5790.61
149_R161_G0.5790.61
420_G424_P0.5780.61
507_L556_W0.5780.61
566_L572_F0.5780.61
556_W657_F0.5770.60
682_D693_N0.5760.60
145_P173_G0.5760.60
301_Q406_A0.5760.60
234_K237_N0.5750.60
233_R236_A0.5750.60
229_Q237_N0.5750.60
314_T318_F0.5740.60
228_V231_E0.5740.60
339_G372_T0.5740.60
268_L273_V0.5740.60
572_F585_D0.5730.60
547_F599_V0.5730.60
233_R237_N0.5720.60
279_M603_V0.5710.60
693_N697_V0.5710.60
266_R270_D0.5710.60
450_V453_A0.5710.60
287_L292_H0.5700.59
426_E433_L0.5700.59
110_A114_S0.5700.59
127_A208_F0.5700.59
248_V253_W0.5700.59
184_N224_P0.5690.59
554_Y570_N0.5690.59
282_T611_R0.5690.59
148_R196_N0.5690.59
146_N376_N0.5690.59
233_R453_A0.5670.59
124_T319_R0.5670.59
161_G201_L0.5670.59
566_L603_V0.5660.59
140_F204_D0.5650.59
339_G368_Q0.5650.59
584_L588_L0.5650.59
121_P384_N0.5650.59
467_S519_F0.5640.59
213_R310_R0.5640.59
196_N200_R0.5640.59
587_H591_G0.5640.59
471_D518_N0.5630.59
544_W717_P0.5620.58
277_K649_N0.5610.58
482_N510_G0.5600.58
113_L116_G0.5600.58
281_F603_V0.5590.58
242_P617_H0.5590.58
239_F447_G0.5590.58
682_D717_P0.5580.58
501_Q634_K0.5580.58
273_V284_L0.5580.58
143_W382_V0.5570.58
708_Q711_L0.5570.58
109_D112_L0.5570.58
702_I712_S0.5570.58
545_Q549_N0.5560.58
245_I479_Y0.5560.58
214_P217_A0.5550.57
534_S538_R0.5550.57
545_Q689_S0.5540.57
613_H649_N0.5540.57
219_L223_L0.5520.57
210_A310_R0.5520.57
703_A709_H0.5520.57
413_R433_L0.5510.57
252_S461_T0.5510.57
413_R435_A0.5510.57
578_W584_L0.5500.57
108_M114_S0.5500.57
144_A352_D0.5480.57
236_A241_A0.5480.57
380_R384_N0.5480.57
555_G719_A0.5480.57
552_A719_A0.5480.57
157_N160_D0.5470.56
231_E323_D0.5470.56
682_D689_S0.5460.56
522_P535_I0.5450.56
471_D632_D0.5450.56
665_Y705_H0.5450.56
250_L325_A0.5450.56
185_G220_I0.5440.56
127_A140_F0.5430.56
237_N241_A0.5430.56
209_E212_M0.5430.56
580_H585_D0.5410.56
224_P316_D0.5400.55
119_L445_I0.5400.55
472_M518_N0.5400.55
189_K201_L0.5400.55
549_N552_A0.5390.55
702_I708_Q0.5390.55
188_Y204_D0.5380.55
413_R430_R0.5380.55
228_V235_K0.5370.55
638_V654_A0.5360.55
652_I667_F0.5350.55
337_V340_H0.5350.55
422_W430_R0.5340.55
555_G559_A0.5340.55
230_T236_A0.5340.55
609_T617_H0.5330.54
467_S621_F0.5330.54
366_Y373_L0.5330.54
627_E642_V0.5320.54
462_D487_H0.5320.54
187_L190_Y0.5320.54
618_E645_D0.5320.54
630_V704_S0.5310.54
192_M351_F0.5310.54
184_N225_E0.5310.54
445_I449_Q0.5300.54
130_D137_G0.5290.54
302_P343_T0.5290.54
697_V700_D0.5280.54
428_G431_E0.5280.54
255_R587_H0.5280.54
377_Y409_S0.5280.54
103_P106_Q0.5280.54
453_A478_W0.5270.54
413_R434_E0.5270.54
633_D665_Y0.5260.53
460_S486_M0.5260.53
274_P571_E0.5250.53
160_D165_P0.5240.53
602_L605_D0.5230.53
715_L721_I0.5230.53
557_M566_L0.5230.53
239_F454_V0.5230.53
106_Q118_H0.5220.53
348_L351_F0.5210.53
137_G181_G0.5210.53
629_L640_I0.5200.53
130_D136_T0.5200.53
642_V670_N0.5190.53
115_E118_H0.5190.53
365_G423_I0.5180.52
619_L648_G0.5180.52
489_T507_L0.5180.52
238_Q241_A0.5180.52
582_A586_W0.5180.52
483_L486_M0.5170.52
505_D639_L0.5170.52
142_V192_M0.5170.52
112_L116_G0.5160.52
679_L722_W0.5160.52
376_N380_R0.5160.52
647_E650_E0.5160.52
146_N379_R0.5150.52
146_N355_N0.5150.52
458_E526_D0.5140.52
208_F221_C0.5140.52
437_E444_R0.5140.52
295_D310_R0.5140.52
118_H384_N0.5130.52
650_E675_W0.5120.52
329_G713_L0.5120.52
493_M523_L0.5120.52
412_Y461_T0.5120.52
537_D543_A0.5110.51
119_L441_N0.5110.51
210_A218_S0.5110.51
109_D121_P0.5110.51
151_S199_L0.5100.51
233_R238_Q0.5100.51
122_Y128_H0.5100.51
486_M527_E0.5090.51
579_N583_S0.5090.51
253_W275_Y0.5090.51
588_L591_G0.5090.51
268_L271_Q0.5090.51
704_S711_L0.5080.51
188_Y207_A0.5080.51
693_N696_T0.5070.51
556_W560_F0.5070.51
123_E449_Q0.5070.51
107_E110_A0.5070.51
511_I514_N0.5060.51
249_H292_H0.5060.51
458_E525_H0.5040.50
535_I550_L0.5030.50
294_F301_Q0.5010.50
510_G639_L0.5010.50
355_N358_E0.5000.50
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3k1dA 1 0.9766 100 0.208 Contact Map
1m7xA 1 0.8146 100 0.353 Contact Map
3amlA 1 0.8654 100 0.365 Contact Map
4bzyA 1 0.8297 100 0.394 Contact Map
3wdhA 1 0.8585 100 0.468 Contact Map
2e8yA 1 0.864 100 0.482 Contact Map
1bf2A 1 0.8008 100 0.492 Contact Map
4j7rA 2 0.8269 100 0.493 Contact Map
2wanA 1 0.8942 100 0.497 Contact Map
3fawA 1 0.8887 100 0.511 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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