TYRR - ECOLI - GREMLIN Contacts

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TYRR - Transcriptional regulatory protein TyrR

UniProt:	P07604	Sequences: MRLEVFCEDRLGLTRELLDLLVLRGIDLRGIEIDPIGRIYLNFAELEFESFSSLMAEIRRIAGVTDVRTVPWMPSEREHLALSALLEALPEPVLSVDMKSKVDMANPASCQLFGQKLDRLRNHTAAQLINGFNFLRWLESEPQDSHNEHVVINGQNFLMEITPVYLQDENDQHVLTGAVVMLRSTIRMGRQLQNVAAQDVSAFSQIVAVSPKMKHVVEQAQKLAMLSAPLLITGDTGTGKDLFAYACHQASPRAGKPYLALNCASIPEDAVESELFGHAPEGKKGFFEQANGGSVLLDEIGEMSPRMQAKLLRFLNDGTFRRVGEDHEVHVDVRVICATQKNLVELVQKGMFREDLYYRLNVLTLNLPPLRDCPQDIMPLTELFVARFADEQGVPRPKLAADLNTVLTRYAWPGNVRQLKNAIYRALTQLDGYELRPQDILLPDYDAATVAVGEDAMEGSLDEITSRFERSVLTQLYRNYPSTRKLAKRLGVSHTAIANKLREYGLSQKKNEE	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG11042
Length:	513 (427)
Sequences:	5343 (4468)
Seq/√Len:	216.2

ECOLI - TYRR DHAR YGEV HYFR FHLA RTCR PRPR NORR NTRC GLRR ATOC ZRAR
BACSU - YQIR ACOR ROCR

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
235_D	371_R	3.757	1.00
479_N	489_R	3.749	1.00
346_L	351_M	3.642	1.00
345_E	349_K	3.639	1.00
387_R	420_K	3.581	1.00
288_E	322_R	3.508	1.00
264_A	309_A	3.147	1.00
268_E	306_R	3.092	1.00
470_R	474_T	2.986	1.00
469_E	500_K	2.859	1.00
296_L	338_A	2.783	1.00
292_G	332_D	2.756	1.00
222_K	431_D	2.717	1.00
342_N	345_E	2.599	1.00
400_A	436_R	2.553	1.00
341_K	346_L	2.546	1.00
479_N	486_L	2.527	1.00
208_A	213_M	2.470	1.00
403_L	407_L	2.439	1.00
319_T	328_E	2.434	1.00
286_F	321_R	2.434	1.00
320_F	331_V	2.391	1.00
97_D	101_K	2.380	1.00
378_M	408_T	2.371	1.00
485_K	488_K	2.317	1.00
319_T	330_H	2.278	1.00
220_A	243_F	2.250	1.00
253_R	332_D	2.246	1.00
241_D	313_R	2.210	1.00
410_Y	413_P	2.182	1.00
478_R	489_R	2.174	1.00
210_S	375_Q	2.152	1.00
321_R	328_E	2.133	1.00
381_T	423_I	2.111	1.00
378_M	404_N	2.095	1.00
316_N	420_K	2.080	1.00
287_F	295_V	2.074	1.00
110_C	117_L	2.032	1.00
216_V	365_L	2.031	1.00
101_K	124_T	2.020	1.00
412_W	422_A	1.976	1.00
203_F	246_A	1.961	1.00
325_E	329_V	1.940	1.00
492_V	497_I	1.940	1.00
399_L	423_I	1.936	1.00
301_G	339_T	1.924	1.00
94_L	102_V	1.920	1.00
206_I	213_M	1.911	1.00
212_K	372_D	1.900	1.00
166_L	170_N	1.899	1.00
278_H	282_G	1.895	1.00
345_E	348_Q	1.887	1.00
484_R	494_H	1.882	1.00
216_V	243_F	1.877	1.00
381_T	399_L	1.876	1.00
279_A	282_G	1.871	1.00
403_L	437_P	1.843	1.00
346_L	349_K	1.842	1.00
468_F	472_V	1.788	1.00
272_E	310_K	1.782	1.00
287_F	314_F	1.771	1.00
402_D	437_P	1.763	1.00
315_L	335_V	1.760	1.00
209_V	379_P	1.759	1.00
398_K	434_E	1.733	1.00
466_S	503_E	1.732	1.00
385_V	427_L	1.718	1.00
406_V	437_P	1.702	1.00
374_P	411_A	1.700	1.00
374_P	377_I	1.699	1.00
256_K	292_G	1.688	1.00
400_A	403_L	1.685	1.00
123_H	127_Q	1.676	1.00
228_A	428_T	1.665	1.00
400_A	434_E	1.662	1.00
377_I	381_T	1.649	1.00
271_V	307_M	1.637	1.00
228_A	424_Y	1.620	1.00
403_L	435_L	1.602	1.00
233_T	366_N	1.596	1.00
465_T	468_F	1.579	1.00
337_C	360_L	1.577	1.00
295_V	335_V	1.563	1.00
291_N	332_D	1.561	1.00
473_L	497_I	1.559	1.00
238_T	367_L	1.543	1.00
227_S	253_R	1.492	1.00
216_V	220_A	1.484	1.00
107_P	111_Q	1.484	1.00
203_F	220_A	1.483	1.00
476_L	486_L	1.482	1.00
380_L	384_F	1.482	1.00
230_L	247_C	1.460	1.00
108_A	111_Q	1.454	1.00
288_E	329_V	1.452	1.00
485_K	489_R	1.452	1.00
231_L	337_C	1.450	1.00
410_Y	418_Q	1.449	1.00
464_I	472_V	1.443	1.00
348_Q	354_E	1.434	1.00
116_K	119_R	1.434	1.00
105_A	120_L	1.432	1.00
464_I	468_F	1.431	1.00
500_K	504_Y	1.426	1.00
483_T	494_H	1.424	1.00
91_E	180_V	1.416	1.00
207_V	383_L	1.416	1.00
388_F	423_I	1.410	1.00
436_R	439_D	1.408	1.00
343_L	352_F	1.407	1.00
220_A	365_L	1.406	1.00
87_E	107_P	1.403	1.00
287_F	333_V	1.393	1.00
243_F	367_L	1.386	1.00
291_N	331_V	1.386	1.00
378_M	381_T	1.382	1.00
232_I	244_A	1.382	1.00
213_M	216_V	1.381	1.00
405_T	409_R	1.376	1.00
223_L	363_L	1.368	1.00
430_L	439_D	1.363	1.00
495_T	498_A	1.362	1.00
441_L	445_Y	1.359	1.00
475_Q	478_R	1.359	1.00
482_S	494_H	1.353	1.00
228_A	392_Q	1.348	1.00
344_V	348_Q	1.337	1.00
302_E	341_K	1.333	1.00
136_R	140_S	1.330	1.00
388_F	427_L	1.327	1.00
320_F	330_H	1.315	1.00
89_L	93_V	1.312	1.00
233_T	364_T	1.306	1.00
374_P	378_M	1.302	1.00
235_D	369_P	1.295	1.00
493_S	496_A	1.287	1.00
426_A	435_L	1.287	1.00
384_F	423_I	1.280	1.00
221_Q	250_A	1.267	1.00
382_E	404_N	1.263	1.00
471_S	475_Q	1.256	1.00
486_L	489_R	1.253	1.00
271_V	275_L	1.249	1.00
291_N	333_V	1.246	1.00
322_R	325_E	1.244	1.00
494_H	498_A	1.240	1.00
496_A	499_N	1.236	1.00
473_L	500_K	1.232	1.00
383_L	387_R	1.227	1.00
208_A	217_V	1.220	1.00
404_N	408_T	1.220	1.00
314_F	320_F	1.216	1.00
484_R	488_K	1.213	1.00
384_F	388_F	1.208	1.00
389_A	395_P	1.206	1.00
286_F	289_Q	1.190	1.00
473_L	486_L	1.189	1.00
189_G	193_Q	1.180	1.00
283_K	326_D	1.179	1.00
460_S	463_E	1.169	1.00
473_L	501_L	1.167	1.00
467_R	471_S	1.166	1.00
205_Q	249_Q	1.163	1.00
268_E	304_S	1.163	1.00
483_T	497_I	1.160	1.00
441_L	444_D	1.159	1.00
217_V	221_Q	1.151	1.00
278_H	283_K	1.150	1.00
482_S	485_K	1.149	1.00
422_A	426_A	1.145	1.00
389_A	396_R	1.134	1.00
206_I	242_L	1.133	1.00
217_V	243_F	1.128	1.00
483_T	498_A	1.127	1.00
165_Y	172_Q	1.126	1.00
366_N	372_D	1.122	1.00
233_T	344_V	1.121	1.00
495_T	499_N	1.114	1.00
206_I	243_F	1.109	1.00
289_Q	325_E	1.108	1.00
248_H	294_S	1.106	1.00
399_L	404_N	1.106	1.00
295_V	314_F	1.106	1.00
284_K	326_D	1.105	1.00
96_V	175_L	1.103	1.00
225_M	252_P	1.094	1.00
245_Y	249_Q	1.094	1.00
92_P	106_N	1.093	1.00
405_T	408_T	1.092	1.00
199_D	249_Q	1.092	1.00
471_S	474_T	1.087	1.00
465_T	472_V	1.086	1.00
110_C	116_K	1.085	1.00
435_L	440_I	1.084	1.00
389_A	427_L	1.081	1.00
384_F	420_K	1.074	1.00
476_L	479_N	1.064	1.00
264_A	302_E	1.064	1.00
246_A	250_A	1.062	1.00
392_Q	428_T	1.059	1.00
476_L	480_Y	1.055	1.00
219_Q	429_Q	1.054	1.00
402_D	436_R	1.052	1.00
227_S	252_P	1.052	1.00
192_L	195_V	1.051	1.00
137_W	140_S	1.050	1.00
399_L	403_L	1.049	1.00
469_E	473_L	1.048	1.00
322_R	329_V	1.036	1.00
284_K	322_R	1.030	1.00
425_R	429_Q	1.028	1.00
228_A	362_V	1.028	1.00
208_A	379_P	1.027	1.00
218_E	221_Q	1.026	1.00
474_T	506_L	1.026	1.00
253_R	333_V	1.023	1.00
201_S	245_Y	1.022	1.00
259_L	289_Q	1.013	1.00
92_P	112_L	1.012	1.00
80_L	83_S	1.011	1.00
97_D	103_D	1.010	1.00
301_G	341_K	1.009	1.00
227_S	391_E	1.008	1.00
244_A	258_Y	1.005	1.00
226_L	428_T	1.005	1.00
260_A	313_R	1.004	1.00
481_P	486_L	1.000	1.00
370_L	419_L	1.000	1.00
394_V	397_P	1.000	1.00
474_T	477_Y	0.998	1.00
344_V	443_P	0.997	1.00
401_A	405_T	0.997	1.00
115_Q	120_L	0.994	1.00
302_E	340_Q	0.994	1.00
440_I	444_D	0.990	1.00
213_M	217_V	0.987	1.00
79_H	83_S	0.985	1.00
271_V	303_M	0.983	1.00
135_L	139_E	0.982	1.00
83_S	87_E	0.982	1.00
220_A	250_A	0.981	1.00
397_P	433_Y	0.979	1.00
425_R	441_L	0.978	1.00
335_V	360_L	0.970	1.00
213_M	243_F	0.969	1.00
492_V	496_A	0.969	1.00
318_G	330_H	0.967	1.00
426_A	430_L	0.957	1.00
105_A	110_C	0.953	1.00
410_Y	444_D	0.953	1.00
212_K	215_H	0.953	1.00
432_G	439_D	0.953	1.00
476_L	481_P	0.952	1.00
466_S	504_Y	0.949	1.00
464_I	467_R	0.935	0.99
107_P	110_C	0.934	0.99
262_N	265_S	0.933	0.99
486_L	497_I	0.932	0.99
301_G	340_Q	0.931	0.99
374_P	408_T	0.929	0.99
94_L	109_S	0.928	0.99
460_S	491_G	0.927	0.99
284_K	289_Q	0.925	0.99
209_V	214_K	0.924	0.99
479_N	485_K	0.921	0.99
166_L	169_E	0.919	0.99
385_V	389_A	0.914	0.99
136_R	139_E	0.914	0.99
267_P	323_V	0.914	0.99
425_R	428_T	0.908	0.99
95_S	103_D	0.908	0.99
214_K	217_V	0.907	0.99
385_V	399_L	0.903	0.99
241_D	260_A	0.896	0.99
232_I	243_F	0.893	0.99
258_Y	293_G	0.893	0.99
279_A	283_K	0.892	0.99
391_E	424_Y	0.892	0.99
497_I	501_L	0.890	0.99
493_S	499_N	0.887	0.99
386_A	390_D	0.881	0.99
341_K	351_M	0.880	0.99
187_R	191_Q	0.877	0.99
287_F	331_V	0.877	0.99
217_V	220_A	0.873	0.99
211_P	215_H	0.871	0.99
389_A	394_V	0.871	0.99
232_I	367_L	0.867	0.99
245_Y	260_A	0.866	0.99
388_F	424_Y	0.864	0.99
124_T	127_Q	0.862	0.99
185_T	188_M	0.861	0.99
477_Y	480_Y	0.858	0.99
141_E	165_Y	0.853	0.99
381_T	404_N	0.852	0.99
226_L	363_L	0.850	0.99
241_D	317_D	0.849	0.99
289_Q	326_D	0.848	0.99
487_A	497_I	0.847	0.99
215_H	219_Q	0.846	0.99
501_L	506_L	0.845	0.99
362_V	421_N	0.845	0.99
223_L	365_L	0.843	0.99
465_T	469_E	0.843	0.99
400_A	437_P	0.838	0.99
381_T	407_L	0.838	0.99
203_F	217_V	0.836	0.99
291_N	329_V	0.836	0.99
220_A	247_C	0.835	0.99
229_P	337_C	0.832	0.99
374_P	409_R	0.831	0.99
302_E	339_T	0.830	0.99
141_E	172_Q	0.825	0.99
288_E	320_F	0.821	0.99
498_A	502_R	0.818	0.99
470_R	506_L	0.816	0.99
101_K	122_N	0.813	0.99
399_L	435_L	0.812	0.99
94_L	105_A	0.807	0.99
218_E	431_D	0.805	0.98
229_P	318_G	0.805	0.98
163_P	167_Q	0.804	0.98
215_H	218_E	0.804	0.98
137_W	144_D	0.799	0.98
223_L	230_L	0.797	0.98
483_T	501_L	0.793	0.98
232_I	365_L	0.791	0.98
186_I	190_R	0.783	0.98
270_A	273_S	0.783	0.98
484_R	498_A	0.781	0.98
477_Y	481_P	0.779	0.98
473_L	490_L	0.778	0.98
273_S	278_H	0.778	0.98
283_K	286_F	0.776	0.98
203_F	250_A	0.773	0.98
389_A	397_P	0.772	0.98
233_T	340_Q	0.770	0.98
267_P	272_E	0.769	0.98
312_L	359_R	0.769	0.98
220_A	246_A	0.769	0.98
163_P	166_L	0.768	0.98
397_P	430_L	0.767	0.98
191_Q	194_N	0.760	0.98
89_L	92_P	0.757	0.98
214_K	218_E	0.756	0.98
470_R	504_Y	0.755	0.98
151_V	154_G	0.753	0.98
131_G	134_F	0.753	0.98
459_G	467_R	0.750	0.98
260_A	319_T	0.748	0.98
228_A	363_L	0.748	0.98
406_V	444_D	0.747	0.98
208_A	214_K	0.745	0.97
219_Q	425_R	0.741	0.97
204_S	221_Q	0.739	0.97
494_H	497_I	0.739	0.97
378_M	382_E	0.739	0.97
140_S	144_D	0.738	0.97
266_I	275_L	0.737	0.97
493_S	498_A	0.735	0.97
499_N	503_E	0.735	0.97
361_N	425_R	0.735	0.97
392_Q	427_L	0.734	0.97
166_L	173_H	0.734	0.97
79_H	82_L	0.733	0.97
216_V	367_L	0.731	0.97
397_P	427_L	0.731	0.97
165_Y	170_N	0.731	0.97
300_I	303_M	0.730	0.97
109_S	113_F	0.728	0.97
388_F	420_K	0.727	0.97
287_F	320_F	0.727	0.97
501_L	504_Y	0.726	0.97
382_E	386_A	0.726	0.97
253_R	256_K	0.724	0.97
184_S	189_G	0.721	0.97
177_G	180_V	0.720	0.97
105_A	109_S	0.720	0.97
476_L	483_T	0.718	0.97
356_L	360_L	0.718	0.97
498_A	501_L	0.717	0.97
461_L	464_I	0.717	0.97
344_V	347_V	0.716	0.97
260_A	317_D	0.714	0.97
227_S	334_R	0.713	0.97
313_R	316_N	0.713	0.97
126_A	130_N	0.713	0.97
394_V	427_L	0.711	0.97
233_T	339_T	0.710	0.97
270_A	340_Q	0.710	0.97
292_G	333_V	0.707	0.97
115_Q	119_R	0.706	0.97
241_D	316_N	0.706	0.97
247_C	336_I	0.704	0.96
126_A	135_L	0.703	0.96
369_P	372_D	0.702	0.96
373_C	376_D	0.700	0.96
271_V	310_K	0.700	0.96
361_N	364_T	0.699	0.96
359_R	417_R	0.697	0.96
362_V	424_Y	0.695	0.96
496_A	500_K	0.692	0.96
466_S	470_R	0.691	0.96
94_L	177_G	0.690	0.96
274_E	278_H	0.690	0.96
316_N	359_R	0.690	0.96
298_D	313_R	0.688	0.96
318_G	332_D	0.688	0.96
100_S	124_T	0.684	0.96
424_Y	428_T	0.683	0.96
403_L	436_R	0.682	0.96
313_R	317_D	0.681	0.96
301_G	343_L	0.681	0.96
318_G	333_V	0.680	0.96
320_F	328_E	0.675	0.96
367_L	416_V	0.673	0.95
211_P	214_K	0.673	0.95
388_F	391_E	0.670	0.95
92_P	109_S	0.669	0.95
212_K	375_Q	0.667	0.95
354_E	418_Q	0.667	0.95
207_V	379_P	0.667	0.95
224_A	250_A	0.667	0.95
426_A	439_D	0.665	0.95
140_S	143_Q	0.665	0.95
125_A	134_F	0.664	0.95
426_A	440_I	0.663	0.95
484_R	495_T	0.663	0.95
163_P	168_D	0.662	0.95
303_M	307_M	0.660	0.95
340_Q	359_R	0.660	0.95
481_P	494_H	0.660	0.95
92_P	113_F	0.658	0.95
208_A	376_D	0.658	0.95
388_F	392_Q	0.655	0.95
299_E	340_Q	0.654	0.95
95_S	109_S	0.654	0.95
473_L	504_Y	0.653	0.95
85_L	95_S	0.653	0.95
89_L	178_A	0.652	0.95
284_K	288_E	0.651	0.95
210_S	213_M	0.651	0.95
188_M	195_V	0.650	0.95
161_I	165_Y	0.649	0.94
266_I	272_E	0.648	0.94
95_S	104_M	0.648	0.94
476_L	501_L	0.647	0.94
137_W	161_I	0.647	0.94
188_M	191_Q	0.646	0.94
294_S	334_R	0.646	0.94
381_T	385_V	0.645	0.94
267_P	270_A	0.645	0.94
482_S	498_A	0.645	0.94
352_F	356_L	0.641	0.94
264_A	310_K	0.640	0.94
225_M	250_A	0.639	0.94
440_I	443_P	0.635	0.94
236_T	359_R	0.635	0.94
403_L	426_A	0.633	0.94
299_E	359_R	0.633	0.94
207_V	384_F	0.630	0.94
298_D	359_R	0.629	0.94
150_V	154_G	0.629	0.94
395_P	433_Y	0.628	0.93
341_K	350_G	0.628	0.93
483_T	492_V	0.626	0.93
396_R	399_L	0.626	0.93
182_L	186_I	0.625	0.93
486_L	490_L	0.625	0.93
343_L	347_V	0.625	0.93
235_D	238_T	0.624	0.93
431_D	439_D	0.623	0.93
344_V	357_Y	0.623	0.93
163_P	172_Q	0.621	0.93
165_Y	169_E	0.620	0.93
422_A	425_R	0.620	0.93
209_V	375_Q	0.619	0.93
278_H	323_V	0.619	0.93
203_F	221_Q	0.619	0.93
291_N	330_H	0.618	0.93
211_P	375_Q	0.615	0.93
318_G	331_V	0.613	0.93
174_V	179_V	0.612	0.93
175_L	179_V	0.612	0.93
117_L	121_R	0.610	0.92
377_I	408_T	0.609	0.92
161_I	177_G	0.609	0.92
273_S	340_Q	0.608	0.92
109_S	179_V	0.608	0.92
270_A	323_V	0.608	0.92
227_S	332_D	0.608	0.92
317_D	330_H	0.607	0.92
269_D	272_E	0.606	0.92
200_V	245_Y	0.605	0.92
385_V	398_K	0.603	0.92
286_F	498_A	0.601	0.92
261_L	275_L	0.601	0.92
298_D	340_Q	0.601	0.92
251_S	334_R	0.600	0.92
96_V	102_V	0.598	0.92
273_S	283_K	0.598	0.92
483_T	495_T	0.597	0.92
222_K	394_V	0.596	0.92
238_T	242_L	0.596	0.92
147_N	150_V	0.593	0.91
92_P	179_V	0.593	0.91
148_E	151_V	0.592	0.91
325_E	328_E	0.591	0.91
274_E	352_F	0.590	0.91
462_D	466_S	0.590	0.91
314_F	317_D	0.586	0.91
243_F	246_A	0.586	0.91
425_R	495_T	0.586	0.91
403_L	441_L	0.586	0.91
284_K	320_F	0.585	0.91
261_L	295_V	0.584	0.91
407_L	412_W	0.584	0.91
282_G	325_E	0.583	0.91
355_D	359_R	0.582	0.91
291_N	320_F	0.581	0.91
212_K	216_V	0.580	0.90
87_E	117_L	0.580	0.90
96_V	100_S	0.579	0.90
202_A	205_Q	0.576	0.90
276_F	285_G	0.575	0.90
473_L	506_L	0.575	0.90
294_S	376_D	0.574	0.90
298_D	417_R	0.574	0.90
375_Q	408_T	0.572	0.90
201_S	205_Q	0.572	0.90
202_A	249_Q	0.571	0.90
190_R	194_N	0.571	0.90
310_K	321_R	0.571	0.90
98_M	170_N	0.570	0.90
364_T	425_R	0.569	0.90
278_H	281_E	0.567	0.89
260_A	321_R	0.567	0.89
374_P	379_P	0.566	0.89
304_S	496_A	0.564	0.89
123_H	128_L	0.562	0.89
208_A	212_K	0.560	0.89
100_S	125_A	0.559	0.89
353_R	359_R	0.558	0.89
189_G	192_L	0.558	0.89
188_M	192_L	0.558	0.89
96_V	177_G	0.556	0.89
469_E	504_Y	0.555	0.88
186_I	195_V	0.555	0.88
375_Q	378_M	0.552	0.88
406_V	409_R	0.551	0.88
432_G	436_R	0.550	0.88
385_V	396_R	0.550	0.88
313_R	319_T	0.550	0.88
493_S	500_K	0.550	0.88
347_V	352_F	0.548	0.88
152_I	157_F	0.548	0.88
273_S	338_A	0.547	0.88
202_A	250_A	0.547	0.88
224_A	334_R	0.546	0.88
184_S	187_R	0.546	0.88
382_E	398_K	0.546	0.88
380_L	383_L	0.545	0.88
222_K	429_Q	0.544	0.87
267_P	303_M	0.544	0.87
98_M	173_H	0.544	0.87
464_I	475_Q	0.543	0.87
423_I	426_A	0.542	0.87
387_R	391_E	0.541	0.87
318_G	391_E	0.540	0.87
350_G	354_E	0.539	0.87
377_I	407_L	0.537	0.87
480_Y	494_H	0.535	0.87
268_E	272_E	0.534	0.87
311_L	314_F	0.533	0.86
459_G	464_I	0.533	0.86
353_R	417_R	0.533	0.86
199_D	245_Y	0.532	0.86
339_T	343_L	0.532	0.86
410_Y	441_L	0.532	0.86
174_V	178_A	0.532	0.86
303_M	309_A	0.531	0.86
147_N	152_I	0.531	0.86
494_H	499_N	0.531	0.86
172_Q	175_L	0.530	0.86
304_S	307_M	0.530	0.86
215_H	438_Q	0.530	0.86
363_L	428_T	0.530	0.86
320_F	329_V	0.529	0.86
110_C	114_G	0.528	0.86
383_L	386_A	0.528	0.86
476_L	482_S	0.527	0.86
274_E	282_G	0.527	0.86
177_G	181_M	0.526	0.86
242_L	313_R	0.526	0.86
220_A	336_I	0.526	0.86
125_A	135_L	0.525	0.86
486_L	501_L	0.525	0.86
251_S	294_S	0.525	0.86
113_F	179_V	0.525	0.86
231_L	343_L	0.524	0.85
418_Q	443_P	0.524	0.85
206_I	367_L	0.523	0.85
299_E	417_R	0.523	0.85
277_G	285_G	0.522	0.85
461_L	469_E	0.521	0.85
144_D	154_G	0.520	0.85
271_V	304_S	0.520	0.85
420_K	424_Y	0.519	0.85
146_H	150_V	0.518	0.85
363_L	429_Q	0.516	0.85
110_C	115_Q	0.515	0.85
299_E	338_A	0.515	0.85
186_I	189_G	0.514	0.84
102_V	128_L	0.513	0.84
106_N	109_S	0.512	0.84
148_E	152_I	0.512	0.84
344_V	364_T	0.512	0.84
289_Q	328_E	0.512	0.84
150_V	156_N	0.510	0.84
249_Q	254_A	0.509	0.84
236_T	312_L	0.508	0.84
379_P	383_L	0.508	0.84
215_H	442_L	0.508	0.84
492_V	500_K	0.508	0.84
146_H	149_H	0.507	0.84
301_G	352_F	0.507	0.84
135_L	138_L	0.507	0.84
403_L	406_V	0.507	0.84
238_T	244_A	0.506	0.83
406_V	443_P	0.506	0.83
112_L	179_V	0.505	0.83
181_M	185_T	0.505	0.83
406_V	445_Y	0.505	0.83
82_L	85_L	0.505	0.83
477_Y	482_S	0.504	0.83
381_T	426_A	0.501	0.83
190_R	193_Q	0.501	0.83
278_H	340_Q	0.500	0.83
320_F	323_V	0.500	0.83
461_L	465_T	0.500	0.83

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4l4uA	2	0.7427	100	0.349	Contact Map
1ojlA	3	0.5712	100	0.487	Contact Map
3dzdA	2	0.692	100	0.511	Contact Map
4fwgA	3	0.6023	100	0.658	Contact Map
4qosA	1	0.4678	100	0.686	Contact Map
4qhsA	3	0.462	100	0.686	Contact Map
1qvrA	3	0.8635	100	0.7	Contact Map
1r6bX	1	0.8031	100	0.71	Contact Map
4d2uA	3	0.8207	100	0.713	Contact Map
4ciuA	1	0.8226	100	0.717	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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