SYV - ECOLI - GREMLIN Contacts

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SYV - Valine--tRNA ligase

UniProt:	P07118	Sequences: MEKTYNPQDIEQPLYEHWEKQGYFKPNGDESQESFCIMIPPPNVTGSLHMGHAFQQTIMDTMIRYQRMQGKNTLWQVGTDHAGIATQMVVERKIAAEEGKTRHDYGREAFIDKIWEWKAESGGTITRQMRRLGNSVDWERERFTMDEGLSNAVKEVFVRLYKEDLIYRGKRLVNWDPKLRTAISDLEVENRESKGSMWHIRYPLADGAKTADGKDYLVVATTRPETLLGDTGVAVNPEDPRYKDLIGKYVILPLVNRRIPIVGDEHADMEKGTGCVKITPAHDFNDYEVGKRHALPMINILTFDGDIRESAQVFDTKGNESDVYSSEIPAEFQKLERFAARKAVVAAVDALGLLEEIKPHDLTVPYGDRGGVVIEPMLTDQWYVRADVLAKPAVEAVENGDIQFVPKQYENMYFSWMRDIQDWCISRQLWWGHRIPAWYDEAGNVYVGRNEDEVRKENNLGADVVLRQDEDVLDTWFSSALWTFSTLGWPENTDALRQFHPTSVMVSGFDIIFFWIARMIMMTMHFIKDENGKPQVPFHTVYMTGLIRDDEGQKMSKSKGNVIDPLDMVDGISLPELLEKRTGNMMQPQLADKIRKRTEKQFPNGIEPHGTDALRFTLAALASTGRDINWDMKRLEGYRNFCNKLWNASRFVLMNTEGQDCGFNGGEMTLSLADRWILAEFNQTIKAYREALDSFRFDIAAGILYEFTWNQFCDWYLELTKPVMNGGTEAELRGTRHTLVTVLEGLLRLAHPIIPFITETIWQRVKVLCGITADTIMLQPFPQYDASQVDEAALADTEWLKQAIVAVRNIRAEMNIAPGKPLELLLRGCSADAERRVNENRGFLQTLARLESITVLPADDKGPVSVTKIIDGAELLIPMAGLINKEDELARLAKEVAKIEGEISRIENKLANEGFVARAPEAVIAKEREKLEGYAEAKAKLIEQQAVIAAL	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG11067
Length:	951 (844)
Sequences:	1627 (955)
Seq/√Len:	32.9

ECOLI - SYV SYI
BACSU - SYV SYI
HALSA - SYV SYI SYL
SULSO - SYV SYI SYL2 SYL1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
66_Q	71_K	6.688	1.00
109_A	112_D	5.864	1.00
500_H	523_T	5.441	1.00
434_R	468_Q	5.235	1.00
332_F	347_A	5.004	1.00
113_K	116_E	4.762	1.00
675_R	790_D	4.643	1.00
163_E	525_H	4.607	1.00
302_T	306_D	4.328	1.00
246_I	263_G	4.110	1.00
233_V	250_V	4.057	1.00
573_S	576_E	3.973	1.00
391_K	395_E	3.647	1.00
290_G	295_L	3.587	1.00
249_Y	258_R	3.584	1.00
403_Q	540_T	3.453	1.00
679_A	794_L	3.428	1.00
407_K	410_E	3.381	1.00
335_L	343_A	3.379	1.00
398_E	418_R	3.339	1.00
331_E	347_A	3.316	1.00
149_L	485_S	3.307	1.00
553_Q	559_K	3.220	1.00
492_N	497_R	3.177	1.00
207_G	215_D	3.156	1.00
56_Q	134_N	3.122	1.00
155_E	159_R	3.086	1.00
251_I	256_N	3.057	1.00
162_K	457_E	3.023	1.00
649_S	761_I	2.934	1.00
680_E	711_Q	2.923	1.00
309_E	333_Q	2.867	1.00
201_R	216_Y	2.827	1.00
131_R	570_D	2.774	1.00
346_A	349_D	2.761	1.00
347_A	350_A	2.758	1.00
85_A	369_R	2.690	1.00
98_E	113_K	2.681	1.00
330_A	333_Q	2.667	1.00
162_K	449_R	2.650	1.00
307_I	311_A	2.633	1.00
454_V	458_N	2.610	1.00
217_L	275_C	2.589	1.00
480_A	522_M	2.583	1.00
592_D	595_R	2.580	1.00
394_V	414_F	2.577	1.00
448_G	454_V	2.568	1.00
155_E	449_R	2.563	1.00
194_K	361_D	2.563	1.00
61_T	692_L	2.520	1.00
15_Y	24_F	2.518	1.00
204_L	215_D	2.511	1.00
93_K	97_E	2.447	0.99
690_E	694_S	2.438	0.99
234_A	278_I	2.423	0.99
267_A	271_K	2.370	0.99
578_L	599_E	2.360	0.99
708_T	746_L	2.355	0.99
19_E	130_R	2.352	0.99
750_A	754_I	2.344	0.99
129_M	134_N	2.343	0.99
674_D	716_Y	2.316	0.99
775_T	778_L	2.304	0.99
683_Q	794_L	2.302	0.99
197_M	271_K	2.280	0.99
56_Q	129_M	2.279	0.99
216_Y	355_E	2.272	0.99
451_E	455_R	2.267	0.99
166_I	425_I	2.263	0.99
14_L	760_T	2.262	0.99
33_E	71_K	2.233	0.99
302_T	308_R	2.213	0.99
595_R	599_E	2.205	0.99
288_E	291_K	2.201	0.99
651_F	720_T	2.184	0.99
106_G	109_A	2.174	0.99
180_R	304_D	2.146	0.99
551_E	601_Q	2.130	0.99
251_I	258_R	2.110	0.98
449_R	453_E	2.109	0.98
347_A	351_L	2.103	0.98
201_R	218_V	2.097	0.98
387_D	391_K	2.095	0.98
200_I	348_V	2.093	0.98
384_V	425_I	2.076	0.98
151_N	491_E	2.072	0.98
298_I	308_R	2.071	0.98
459_N	464_V	2.063	0.98
200_I	227_L	2.062	0.98
76_Q	486_T	2.056	0.98
395_E	399_N	2.045	0.98
410_E	414_F	2.044	0.98
409_Y	412_M	2.033	0.98
700_A	753_I	2.024	0.98
192_E	361_D	2.011	0.98
461_G	464_V	2.008	0.98
193_S	366_Y	2.000	0.98
512_I	543_M	1.975	0.98
39_I	129_M	1.974	0.98
671_S	674_D	1.970	0.98
22_G	25_K	1.961	0.98
66_Q	69_Q	1.959	0.97
388_V	391_K	1.950	0.97
507_S	516_I	1.948	0.97
587_Q	590_L	1.945	0.97
205_A	258_R	1.941	0.97
238_E	265_E	1.937	0.97
467_R	470_E	1.932	0.97
441_E	467_R	1.929	0.97
453_E	457_E	1.921	0.97
254_L	347_A	1.919	0.97
142_R	482_W	1.918	0.97
201_R	355_E	1.911	0.97
403_Q	407_K	1.885	0.97
235_V	261_I	1.873	0.97
398_E	414_F	1.873	0.97
750_A	758_T	1.870	0.97
395_E	398_E	1.870	0.97
459_N	462_A	1.864	0.97
233_V	275_C	1.864	0.97
72_N	498_Q	1.850	0.96
215_D	244_D	1.843	0.96
204_L	207_G	1.828	0.96
205_A	249_Y	1.828	0.96
677_I	707_F	1.819	0.96
232_G	262_V	1.814	0.96
398_E	410_E	1.806	0.96
829_C	855_V	1.780	0.96
689_R	693_D	1.779	0.96
197_M	267_A	1.776	0.95
691_A	700_A	1.773	0.95
685_I	749_L	1.755	0.95
63_I	73_T	1.749	0.95
190_N	363_T	1.744	0.95
505_M	519_M	1.741	0.95
685_I	741_T	1.740	0.95
483_T	500_H	1.733	0.95
160_L	522_M	1.730	0.95
250_V	261_I	1.729	0.95
142_R	148_G	1.722	0.95
402_I	520_I	1.720	0.95
686_K	690_E	1.719	0.95
300_I	307_I	1.718	0.95
688_Y	700_A	1.718	0.95
192_E	363_T	1.707	0.94
191_R	366_Y	1.698	0.94
16_E	20_K	1.685	0.94
460_L	464_V	1.680	0.94
689_R	781_F	1.667	0.94
681_F	745_G	1.665	0.94
207_G	214_K	1.663	0.94
159_R	163_E	1.661	0.94
206_D	248_K	1.660	0.94
23_Y	778_L	1.658	0.93
61_T	619_A	1.656	0.93
101_T	104_D	1.654	0.93
670_L	678_L	1.647	0.93
66_Q	693_D	1.642	0.93
345_V	357_I	1.640	0.93
158_V	449_R	1.639	0.93
763_Q	776_I	1.638	0.93
346_A	350_A	1.638	0.93
306_D	336_E	1.633	0.93
856_L	863_P	1.632	0.93
337_R	375_E	1.628	0.93
302_T	309_E	1.625	0.93
340_A	344_V	1.618	0.93
678_L	685_I	1.615	0.93
827_R	874_E	1.614	0.93
417_M	520_I	1.604	0.92
575_P	579_E	1.595	0.92
199_H	356_E	1.590	0.92
179_L	370_G	1.586	0.92
178_K	372_V	1.575	0.92
266_H	289_V	1.575	0.92
859_D	863_P	1.570	0.91
224_P	345_V	1.568	0.91
129_M	136_V	1.566	0.91
680_E	683_Q	1.561	0.91
616_F	701_A	1.560	0.91
619_A	753_I	1.559	0.91
100_K	104_D	1.557	0.91
156_V	526_F	1.547	0.91
494_D	497_R	1.545	0.91
235_V	246_I	1.543	0.91
57_T	619_A	1.542	0.91
527_I	534_P	1.540	0.91
796_D	839_E	1.540	0.91
331_E	343_A	1.539	0.91
727_G	731_E	1.532	0.90
55_Q	544_T	1.531	0.90
808_R	811_R	1.526	0.90
585_M	590_L	1.526	0.90
692_L	700_A	1.524	0.90
441_E	465_V	1.511	0.90
792_A	796_D	1.510	0.90
487_L	502_T	1.498	0.89
544_T	547_I	1.497	0.89
56_Q	544_T	1.496	0.89
460_L	463_D	1.494	0.89
678_L	741_T	1.492	0.89
402_I	536_V	1.485	0.89
343_A	346_A	1.484	0.89
159_R	492_N	1.480	0.89
217_L	261_I	1.479	0.89
414_F	418_R	1.475	0.89
728_T	731_E	1.475	0.89
69_Q	689_R	1.472	0.89
385_R	388_V	1.469	0.88
824_L	875_L	1.465	0.88
94_I	105_Y	1.458	0.88
550_D	601_Q	1.451	0.88
176_D	367_G	1.431	0.87
25_K	139_E	1.410	0.86
229_G	233_V	1.409	0.86
111_I	114_I	1.409	0.86
308_R	311_A	1.408	0.86
568_M	609_H	1.407	0.86
206_D	214_K	1.407	0.86
810_I	877_I	1.405	0.86
790_D	793_A	1.404	0.86
568_M	630_W	1.397	0.86
307_I	340_A	1.388	0.85
576_E	579_E	1.385	0.85
170_K	380_D	1.383	0.85
844_L	848_A	1.378	0.85
356_E	363_T	1.375	0.85
17_H	21_Q	1.370	0.85
811_R	816_I	1.370	0.85
860_D	863_P	1.368	0.85
394_V	418_R	1.366	0.84
38_M	502_T	1.365	0.84
681_F	742_V	1.363	0.84
93_K	120_E	1.359	0.84
100_K	109_A	1.355	0.84
578_L	595_R	1.355	0.84
682_N	789_V	1.355	0.84
95_A	99_G	1.347	0.84
684_T	749_L	1.335	0.83
47_S	124_T	1.332	0.83
100_K	105_Y	1.323	0.82
302_T	307_I	1.319	0.82
29_D	32_Q	1.318	0.82
437_A	447_V	1.308	0.82
835_R	839_E	1.307	0.82
101_T	106_G	1.298	0.81
38_M	482_W	1.298	0.81
658_G	736_R	1.295	0.81
678_L	788_Q	1.294	0.81
838_N	841_R	1.293	0.81
404_F	512_I	1.287	0.81
266_H	363_T	1.287	0.81
483_T	523_T	1.282	0.80
32_Q	71_K	1.280	0.80
219_V	295_L	1.280	0.80
505_M	516_I	1.279	0.80
65_Y	692_L	1.275	0.80
687_A	690_E	1.273	0.80
105_Y	109_A	1.271	0.80
343_A	347_A	1.269	0.80
834_E	838_N	1.253	0.79
79_T	126_T	1.252	0.79
196_S	359_P	1.250	0.79
21_Q	774_D	1.247	0.78
670_L	734_G	1.240	0.78
232_G	278_I	1.238	0.78
856_L	862_G	1.238	0.78
203_P	216_Y	1.238	0.78
23_Y	777_M	1.238	0.78
413_Y	520_I	1.237	0.78
123_G	126_T	1.236	0.78
199_H	220_A	1.234	0.78
234_A	275_C	1.232	0.78
236_N	267_A	1.228	0.77
401_D	535_Q	1.228	0.77
336_E	339_A	1.225	0.77
53_A	56_Q	1.222	0.77
189_E	368_D	1.216	0.77
332_F	335_L	1.216	0.77
685_I	745_G	1.215	0.77
12_Q	16_E	1.212	0.76
445_V	448_G	1.210	0.76
454_V	457_E	1.208	0.76
58_I	506_V	1.206	0.76
301_L	307_I	1.204	0.76
729_E	732_L	1.199	0.76
198_W	227_L	1.195	0.75
594_I	598_T	1.189	0.75
39_I	56_Q	1.187	0.75
572_I	576_E	1.186	0.75
35_F	63_I	1.186	0.75
685_I	689_R	1.181	0.75
540_T	695_F	1.181	0.75
23_Y	774_D	1.178	0.74
204_L	233_V	1.170	0.74
205_A	251_I	1.169	0.74
37_I	63_I	1.166	0.74
551_E	597_R	1.165	0.74
440_D	462_A	1.162	0.73
399_N	524_M	1.162	0.73
67_R	135_S	1.160	0.73
545_G	622_A	1.160	0.73
677_I	742_V	1.158	0.73
39_I	75_W	1.158	0.73
65_Y	689_R	1.155	0.73
55_Q	77_V	1.154	0.73
592_D	596_K	1.153	0.73
567_D	572_I	1.149	0.72
289_V	292_R	1.147	0.72
154_K	158_V	1.146	0.72
581_R	598_T	1.146	0.72
453_E	456_K	1.142	0.72
238_E	269_M	1.141	0.72
674_D	734_G	1.141	0.72
732_L	736_R	1.140	0.72
411_N	415_S	1.139	0.72
126_T	141_E	1.139	0.72
844_L	850_L	1.136	0.72
575_P	599_E	1.133	0.71
415_S	418_R	1.132	0.71
475_T	478_S	1.130	0.71
159_R	162_K	1.128	0.71
218_V	355_E	1.126	0.71
645_L	757_I	1.125	0.71
64_R	755_P	1.124	0.71
482_W	486_T	1.124	0.71
392_P	395_E	1.123	0.71
65_Y	69_Q	1.122	0.71
33_E	66_Q	1.119	0.70
306_D	339_A	1.115	0.70
72_N	499_F	1.114	0.70
588_P	591_A	1.114	0.70
158_V	453_E	1.114	0.70
575_P	578_L	1.112	0.70
744_E	748_R	1.106	0.70
140_R	495_A	1.105	0.69
634_R	638_Y	1.105	0.69
42_P	46_G	1.105	0.69
196_S	357_I	1.103	0.69
858_A	861_K	1.103	0.69
759_E	763_Q	1.099	0.69
830_S	872_G	1.099	0.69
547_I	618_L	1.099	0.69
254_L	348_V	1.095	0.69
204_L	214_K	1.094	0.69
129_M	544_T	1.094	0.69
33_E	72_N	1.090	0.68
411_N	417_M	1.089	0.68
262_V	267_A	1.089	0.68
527_I	535_Q	1.080	0.68
724_M	727_G	1.079	0.68
493_T	496_L	1.079	0.68
232_G	260_P	1.077	0.67
481_L	484_F	1.075	0.67
681_F	685_I	1.074	0.67
440_D	446_Y	1.072	0.67
691_A	703_I	1.072	0.67
8_Q	12_Q	1.071	0.67
832_D	835_R	1.066	0.67
656_T	659_Q	1.066	0.67
303_F	377_M	1.065	0.67
440_D	444_N	1.058	0.66
46_G	49_H	1.056	0.66
629_N	633_K	1.055	0.66
660_D	733_R	1.055	0.66
688_Y	703_I	1.051	0.66
280_P	290_G	1.050	0.65
590_L	593_K	1.048	0.65
287_Y	403_Q	1.048	0.65
555_M	561_N	1.048	0.65
110_F	114_I	1.047	0.65
645_L	743_L	1.045	0.65
412_M	415_S	1.045	0.65
763_Q	775_T	1.043	0.65
405_V	695_F	1.042	0.65
254_L	351_L	1.040	0.65
804_I	808_R	1.039	0.65
687_A	703_I	1.037	0.64
582_T	595_R	1.037	0.64
509_F	543_M	1.035	0.64
831_A	835_R	1.035	0.64
291_K	294_A	1.035	0.64
174_N	376_P	1.033	0.64
824_L	850_L	1.033	0.64
440_D	459_N	1.032	0.64
198_W	224_P	1.031	0.64
275_C	278_I	1.023	0.63
46_G	51_G	1.023	0.63
6_N	9_D	1.022	0.63
682_N	685_I	1.021	0.63
77_V	544_T	1.021	0.63
586_M	594_I	1.020	0.63
683_Q	791_E	1.020	0.63
660_D	663_F	1.013	0.63
858_A	863_P	1.013	0.63
42_P	49_H	1.012	0.63
89_V	92_R	1.012	0.63
176_D	370_G	1.012	0.63
308_R	333_Q	1.012	0.63
586_M	590_L	1.010	0.62
657_E	660_D	1.010	0.62
801_K	811_R	1.007	0.62
582_T	591_A	1.006	0.62
331_E	351_L	1.005	0.62
14_L	704_L	1.004	0.62
23_Y	26_P	1.003	0.62
770_G	773_A	1.002	0.62
497_R	535_Q	0.997	0.61
175_W	182_A	0.995	0.61
200_I	254_L	0.992	0.61
228_L	307_I	0.991	0.61
867_T	874_E	0.991	0.61
446_Y	460_L	0.990	0.61
236_N	266_H	0.988	0.61
55_Q	134_N	0.986	0.60
856_L	860_D	0.983	0.60
13_P	760_T	0.982	0.60
42_P	51_G	0.980	0.60
304_D	308_R	0.980	0.60
200_I	345_V	0.979	0.60
302_T	377_M	0.977	0.60
405_V	540_T	0.975	0.60
176_D	179_L	0.975	0.60
39_I	136_V	0.972	0.59
634_R	637_G	0.972	0.59
715_W	801_K	0.972	0.59
219_V	256_N	0.972	0.59
733_R	737_H	0.972	0.59
17_H	23_Y	0.971	0.59
177_P	305_G	0.970	0.59
453_E	458_N	0.965	0.59
490_P	493_T	0.965	0.59
231_T	280_P	0.963	0.59
300_I	308_R	0.963	0.59
103_H	106_G	0.960	0.58
701_A	753_I	0.958	0.58
392_P	525_H	0.956	0.58
194_K	359_P	0.955	0.58
229_G	300_I	0.955	0.58
403_Q	539_H	0.950	0.58
549_D	561_N	0.948	0.57
40_P	45_T	0.947	0.57
62_M	66_Q	0.947	0.57
401_D	524_M	0.947	0.57
751_H	758_T	0.946	0.57
502_T	505_M	0.944	0.57
488_G	493_T	0.942	0.57
556_S	561_N	0.941	0.57
602_F	605_G	0.941	0.57
75_W	129_M	0.937	0.57
15_Y	23_Y	0.936	0.56
707_F	742_V	0.935	0.56
87_Q	91_E	0.934	0.56
54_F	59_M	0.928	0.56
544_T	550_D	0.925	0.56
856_L	859_D	0.925	0.56
332_F	344_V	0.924	0.55
841_R	845_Q	0.923	0.55
295_L	568_M	0.923	0.55
217_L	295_L	0.921	0.55
231_T	295_L	0.920	0.55
273_T	280_P	0.918	0.55
735_T	738_T	0.915	0.55
392_P	534_P	0.913	0.55
583_G	592_D	0.906	0.54
547_I	691_A	0.905	0.54
27_N	499_F	0.904	0.54
854_T	860_D	0.902	0.54
424_C	428_Q	0.900	0.54
808_R	814_M	0.899	0.53
573_S	578_L	0.898	0.53
472_V	475_T	0.897	0.53
287_Y	425_I	0.896	0.53
799_W	836_R	0.896	0.53
98_E	105_Y	0.895	0.53
40_P	43_N	0.895	0.53
618_L	621_L	0.894	0.53
24_F	27_N	0.892	0.53
725_N	732_L	0.891	0.53
873_A	876_L	0.891	0.53
381_Q	428_Q	0.890	0.53
811_R	815_N	0.885	0.52
132_L	592_D	0.885	0.52
455_R	458_N	0.885	0.52
373_V	445_V	0.884	0.52
811_R	814_M	0.884	0.52
228_L	344_V	0.883	0.52
590_L	594_I	0.883	0.52
835_R	838_N	0.883	0.52
508_G	554_K	0.881	0.52
250_V	275_C	0.879	0.52
266_H	271_K	0.879	0.52
737_H	741_T	0.878	0.52
250_V	289_V	0.878	0.52
176_D	183_I	0.877	0.52
612_D	615_R	0.877	0.52
579_E	582_T	0.876	0.52
447_V	451_E	0.872	0.51
630_W	635_L	0.870	0.51
504_V	542_Y	0.868	0.51
796_D	836_R	0.866	0.51
685_I	788_Q	0.862	0.50
568_M	633_K	0.861	0.50
723_V	735_T	0.859	0.50
448_G	451_E	0.857	0.50
688_Y	749_L	0.856	0.50
385_R	422_D	0.855	0.50
669_T	730_A	0.854	0.50
870_I	873_A	0.854	0.50
36_C	149_L	0.854	0.50
76_Q	142_R	0.854	0.50
844_L	847_L	0.853	0.50
734_G	738_T	0.852	0.50
868_K	871_D	0.851	0.49
271_K	363_T	0.849	0.49
57_T	61_T	0.848	0.49
266_H	364_V	0.848	0.49
236_N	269_M	0.847	0.49
23_Y	27_N	0.845	0.49
122_G	126_T	0.844	0.49
281_A	300_I	0.844	0.49
386_A	402_I	0.844	0.49
524_M	534_P	0.843	0.49
190_N	365_P	0.842	0.49
41_P	60_D	0.841	0.49
180_R	303_F	0.840	0.49
287_Y	291_K	0.838	0.48
35_F	289_V	0.838	0.48
396_A	524_M	0.837	0.48
587_Q	591_A	0.835	0.48
50_M	562_V	0.835	0.48
584_N	590_L	0.833	0.48
246_I	260_P	0.832	0.48
674_D	723_V	0.829	0.48
278_I	294_A	0.828	0.48
476_W	479_S	0.828	0.48
299_N	308_R	0.827	0.47
149_L	383_Y	0.826	0.47
257_R	298_I	0.825	0.47
61_T	753_I	0.825	0.47
354_L	357_I	0.825	0.47
290_G	296_P	0.824	0.47
199_H	358_K	0.824	0.47
133_G	756_F	0.823	0.47
200_I	219_V	0.821	0.47
168_R	175_W	0.819	0.47
65_Y	693_D	0.819	0.47
237_P	263_G	0.815	0.46
380_D	383_Y	0.809	0.46
589_Q	592_D	0.809	0.46
636_E	640_N	0.809	0.46
334_K	337_R	0.808	0.46
584_N	591_A	0.807	0.46
727_G	732_L	0.806	0.46
339_A	343_A	0.805	0.46
567_D	580_K	0.804	0.46
492_N	607_E	0.804	0.46
544_T	635_L	0.803	0.45
9_D	13_P	0.803	0.45
14_L	17_H	0.801	0.45
121_S	181_T	0.799	0.45
379_T	627_D	0.798	0.45
423_W	432_G	0.793	0.45
674_D	717_L	0.793	0.45
262_V	289_V	0.792	0.45
443_G	704_L	0.792	0.45
448_G	458_N	0.791	0.44
645_L	708_T	0.790	0.44
500_H	527_I	0.788	0.44
509_F	559_K	0.787	0.44
239_D	242_Y	0.786	0.44
299_N	302_T	0.785	0.44
550_D	650_R	0.783	0.44
578_L	598_T	0.783	0.44
396_A	401_D	0.783	0.44
691_A	699_I	0.783	0.44
459_N	463_D	0.782	0.44
390_A	420_I	0.781	0.44
523_T	527_I	0.778	0.43
38_M	142_R	0.778	0.43
579_E	595_R	0.777	0.43
200_I	228_L	0.776	0.43
40_P	44_V	0.775	0.43
597_R	601_Q	0.775	0.43
456_K	460_L	0.775	0.43
266_H	278_I	0.774	0.43
156_V	477_F	0.774	0.43
287_Y	297_M	0.773	0.43
28_G	32_Q	0.773	0.43
559_K	586_M	0.772	0.43
151_N	154_K	0.772	0.43
217_L	233_V	0.770	0.43
301_L	377_M	0.769	0.43
53_A	618_L	0.767	0.43
53_A	57_T	0.765	0.42
161_Y	447_V	0.765	0.42
6_N	13_P	0.764	0.42
160_L	166_I	0.764	0.42
748_R	779_Q	0.764	0.42
451_E	468_Q	0.762	0.42
66_Q	73_T	0.762	0.42
871_D	876_L	0.761	0.42
219_V	231_T	0.760	0.42
669_T	734_G	0.759	0.42
482_W	627_D	0.758	0.42
401_D	670_L	0.757	0.42
845_Q	851_E	0.757	0.42
147_E	151_N	0.757	0.42
746_L	750_A	0.755	0.42
550_D	597_R	0.754	0.41
82_A	85_A	0.754	0.41
60_D	64_R	0.753	0.41
386_A	417_M	0.753	0.41
566_L	570_D	0.751	0.41
231_T	290_G	0.751	0.41
437_A	445_V	0.750	0.41
574_L	577_L	0.750	0.41
586_M	591_A	0.750	0.41
675_R	776_I	0.750	0.41
399_N	600_K	0.749	0.41
17_H	20_K	0.749	0.41
55_Q	506_V	0.748	0.41
585_M	594_I	0.745	0.41
415_S	419_D	0.745	0.41
453_E	462_A	0.744	0.41
645_L	754_I	0.743	0.41
483_T	534_P	0.742	0.40
865_S	876_L	0.740	0.40
807_V	811_R	0.739	0.40
300_I	310_S	0.739	0.40
303_F	379_T	0.738	0.40
74_L	499_F	0.737	0.40
838_N	844_L	0.737	0.40
47_S	562_V	0.736	0.40
131_R	566_L	0.736	0.40
77_V	138_W	0.733	0.40
587_Q	594_I	0.733	0.40
50_M	568_M	0.732	0.40
219_V	280_P	0.732	0.40
458_N	463_D	0.731	0.40
688_Y	742_V	0.731	0.40
869_I	872_G	0.731	0.40
591_A	599_E	0.730	0.40
40_P	59_M	0.730	0.40
62_M	697_F	0.730	0.40
289_V	550_D	0.730	0.40
385_R	750_A	0.730	0.40
55_Q	618_L	0.730	0.40
783_Q	787_S	0.728	0.39
179_L	367_G	0.727	0.39
394_V	417_M	0.726	0.39
829_C	833_A	0.725	0.39
366_Y	373_V	0.723	0.39
395_E	403_Q	0.721	0.39
56_Q	59_M	0.721	0.39
688_Y	781_F	0.720	0.39
41_P	46_G	0.720	0.39
869_I	874_E	0.720	0.39
554_K	561_N	0.719	0.39
184_S	187_E	0.719	0.39
227_L	252_L	0.719	0.39
199_H	218_V	0.718	0.39
231_T	297_M	0.718	0.39
150_S	485_S	0.718	0.39
837_V	853_I	0.716	0.38
865_S	868_K	0.716	0.38
800_L	824_L	0.716	0.38
71_K	281_A	0.716	0.38
48_L	52_H	0.715	0.38
38_M	56_Q	0.714	0.38
204_L	216_Y	0.712	0.38
861_K	872_G	0.711	0.38
224_P	227_L	0.710	0.38
289_V	365_P	0.709	0.38
866_V	873_A	0.709	0.38
797_T	800_L	0.708	0.38
81_H	125_I	0.707	0.38
856_L	861_K	0.706	0.38
809_N	874_E	0.706	0.38
671_S	723_V	0.706	0.38
440_D	467_R	0.704	0.37
718_E	721_K	0.703	0.37
423_W	426_S	0.703	0.37
395_E	675_R	0.702	0.37
621_L	629_N	0.702	0.37
367_G	372_V	0.702	0.37
192_E	693_D	0.701	0.37
332_F	343_A	0.701	0.37
866_V	875_L	0.701	0.37
161_Y	164_D	0.701	0.37
549_D	565_P	0.700	0.37
796_D	840_N	0.700	0.37
148_G	491_E	0.699	0.37
666_G	733_R	0.698	0.37
171_R	626_R	0.697	0.37
733_R	736_R	0.696	0.37
192_E	678_L	0.696	0.37
346_A	645_L	0.696	0.37
659_Q	737_H	0.694	0.37
101_T	114_I	0.694	0.37
666_G	670_L	0.693	0.37
672_L	797_T	0.693	0.37
301_L	306_D	0.693	0.37
47_S	128_Q	0.692	0.37
238_E	263_G	0.692	0.37
230_D	277_K	0.691	0.36
162_K	458_N	0.691	0.36
574_L	603_P	0.690	0.36
600_K	604_N	0.690	0.36
377_M	383_Y	0.689	0.36
277_K	514_F	0.689	0.36
188_V	469_D	0.688	0.36
172_L	378_L	0.688	0.36
181_T	622_A	0.688	0.36
349_D	352_G	0.688	0.36
154_K	468_Q	0.686	0.36
458_N	461_G	0.686	0.36
811_R	820_K	0.686	0.36
465_V	539_H	0.685	0.36
177_P	372_V	0.685	0.36
692_L	753_I	0.684	0.36
408_Q	415_S	0.683	0.36
10_I	14_L	0.682	0.36
232_G	750_A	0.682	0.36
296_P	310_S	0.682	0.36
344_V	841_R	0.681	0.36
16_E	19_E	0.681	0.36
803_A	806_A	0.680	0.36
548_R	627_D	0.679	0.36
870_I	875_L	0.679	0.36
671_S	731_E	0.679	0.36
543_M	624_T	0.679	0.36
157_F	166_I	0.678	0.35
283_D	511_I	0.678	0.35
75_W	136_V	0.678	0.35
145_M	192_E	0.678	0.35
585_M	592_D	0.675	0.35
593_K	597_R	0.675	0.35
115_W	119_A	0.674	0.35
726_G	731_E	0.674	0.35
190_N	362_L	0.674	0.35
659_Q	662_G	0.674	0.35
546_L	621_L	0.674	0.35
583_G	590_L	0.673	0.35
483_T	486_T	0.672	0.35
834_E	857_P	0.672	0.35
267_A	363_T	0.671	0.35
545_G	630_W	0.671	0.35
440_D	466_L	0.670	0.35
854_T	863_P	0.670	0.35
424_C	431_W	0.669	0.35
175_W	232_G	0.669	0.35
232_G	363_T	0.669	0.35
291_K	391_K	0.669	0.35
160_L	715_W	0.669	0.35
383_Y	417_M	0.668	0.35
335_L	350_A	0.667	0.35
301_L	308_R	0.666	0.35
704_L	750_A	0.666	0.35
686_K	691_A	0.665	0.35
692_L	781_F	0.665	0.35
678_L	737_H	0.665	0.35
620_A	702_G	0.664	0.34
843_F	846_T	0.664	0.34
130_R	140_R	0.663	0.34
867_T	873_A	0.663	0.34
592_D	597_R	0.663	0.34
645_L	706_E	0.663	0.34
151_N	497_R	0.663	0.34
458_N	462_A	0.662	0.34
450_N	456_K	0.662	0.34
866_V	870_I	0.662	0.34
183_I	377_M	0.661	0.34
131_R	735_T	0.661	0.34
483_T	540_T	0.660	0.34
500_H	535_Q	0.659	0.34
342_K	346_A	0.659	0.34
409_Y	509_F	0.659	0.34
201_R	219_V	0.658	0.34
41_P	49_H	0.658	0.34
674_D	735_T	0.655	0.34
675_R	772_T	0.655	0.34
152_A	488_G	0.654	0.34
582_T	588_P	0.654	0.34
130_R	145_M	0.653	0.34
55_Q	59_M	0.652	0.34
549_D	560_G	0.652	0.34
855_V	860_D	0.652	0.34
437_A	613_A	0.651	0.33
176_D	182_A	0.651	0.33
484_F	523_T	0.651	0.33
273_T	804_I	0.650	0.33
204_L	246_I	0.650	0.33
786_A	789_V	0.649	0.33
228_L	311_A	0.649	0.33
870_I	876_L	0.648	0.33
389_L	524_M	0.648	0.33
513_F	517_A	0.648	0.33
240_P	243_K	0.647	0.33
662_G	665_G	0.647	0.33
66_Q	112_D	0.646	0.33
56_Q	75_W	0.646	0.33
50_M	630_W	0.646	0.33
805_V	809_N	0.646	0.33
117_W	121_S	0.645	0.33
500_H	765_V	0.645	0.33
120_E	127_R	0.644	0.33
555_M	558_S	0.644	0.33
672_L	796_D	0.644	0.33
440_D	464_V	0.643	0.33
115_W	118_K	0.643	0.33
686_K	694_S	0.643	0.33
273_T	348_V	0.642	0.33
758_T	762_W	0.642	0.33
349_D	354_L	0.642	0.33
502_T	682_N	0.641	0.33
409_Y	543_M	0.639	0.33
142_R	149_L	0.639	0.33
809_N	813_E	0.639	0.33
550_D	631_D	0.638	0.33
832_D	836_R	0.637	0.32
680_E	794_L	0.635	0.32
367_G	594_I	0.635	0.32
100_K	113_K	0.635	0.32
392_P	524_M	0.635	0.32
647_N	652_V	0.634	0.32
51_G	60_D	0.632	0.32
700_A	703_I	0.632	0.32
112_D	792_A	0.632	0.32
276_V	289_V	0.632	0.32
166_I	384_V	0.631	0.32
720_T	735_T	0.630	0.32
416_W	422_D	0.630	0.32
785_D	857_P	0.629	0.32
200_I	231_T	0.629	0.32
41_P	51_G	0.629	0.32
679_A	683_Q	0.629	0.32
58_I	61_T	0.628	0.32
227_L	235_V	0.628	0.32
846_T	849_R	0.628	0.32
759_E	776_I	0.628	0.32
127_R	130_R	0.627	0.32
557_K	561_N	0.627	0.32
196_S	354_L	0.626	0.32
216_Y	453_E	0.625	0.32
262_V	690_E	0.625	0.32
36_C	502_T	0.625	0.32
651_F	680_E	0.624	0.31
355_E	358_K	0.624	0.31
77_V	136_V	0.623	0.31
270_E	791_E	0.623	0.31
545_G	626_R	0.622	0.31
292_R	647_N	0.622	0.31
11_E	131_R	0.622	0.31
266_H	269_M	0.621	0.31
200_I	354_L	0.621	0.31
345_V	349_D	0.621	0.31
176_D	438_W	0.621	0.31
845_Q	853_I	0.620	0.31
169_G	422_D	0.620	0.31
261_I	463_D	0.620	0.31
99_G	109_A	0.620	0.31
94_I	101_T	0.620	0.31
231_T	298_I	0.619	0.31
254_L	353_L	0.619	0.31
873_A	877_I	0.619	0.31
645_L	746_L	0.618	0.31
834_E	855_V	0.618	0.31
581_R	594_I	0.618	0.31
155_E	158_V	0.617	0.31
593_K	596_K	0.616	0.31
803_A	837_V	0.616	0.31
448_G	457_E	0.616	0.31
15_Y	22_G	0.615	0.31
175_W	187_E	0.613	0.31
682_N	788_Q	0.613	0.31
672_L	704_L	0.613	0.31
840_N	855_V	0.613	0.31
476_W	515_W	0.612	0.31
379_T	404_F	0.612	0.31
681_F	686_K	0.612	0.31
471_D	476_W	0.612	0.31
81_H	85_A	0.611	0.31
45_T	81_H	0.611	0.31
810_I	813_E	0.610	0.30
308_R	377_M	0.609	0.30
186_L	368_D	0.609	0.30
43_N	81_H	0.607	0.30
85_A	368_D	0.607	0.30
762_W	779_Q	0.606	0.30
82_A	230_D	0.606	0.30
817_A	820_K	0.606	0.30
670_L	738_T	0.606	0.30
563_I	693_D	0.606	0.30
420_I	521_M	0.605	0.30
819_G	849_R	0.604	0.30
392_P	396_A	0.604	0.30
176_D	439_Y	0.603	0.30
422_D	501_P	0.603	0.30
450_N	453_E	0.602	0.30
503_S	851_E	0.602	0.30
91_E	188_V	0.601	0.30
190_N	480_A	0.601	0.30
182_A	760_T	0.601	0.30
81_H	86_T	0.600	0.30
807_V	824_L	0.599	0.30
397_V	413_Y	0.599	0.30
14_L	711_Q	0.599	0.30
219_V	229_G	0.599	0.30
18_W	422_D	0.599	0.30
574_L	606_I	0.599	0.30
236_N	292_R	0.598	0.30
342_K	675_R	0.597	0.30
25_K	370_G	0.597	0.30
386_A	609_H	0.597	0.30
166_I	435_I	0.596	0.30
678_L	753_I	0.596	0.30
48_L	128_Q	0.595	0.29
685_I	737_H	0.595	0.29
48_L	54_F	0.595	0.29
334_K	338_F	0.594	0.29
724_M	844_L	0.593	0.29
679_A	789_V	0.592	0.29
368_D	594_I	0.592	0.29
11_E	611_T	0.591	0.29
688_Y	704_L	0.591	0.29
254_L	311_A	0.590	0.29
409_Y	415_S	0.590	0.29
68_M	748_R	0.589	0.29
137_D	140_R	0.589	0.29
9_D	16_E	0.588	0.29
62_M	695_F	0.588	0.29
851_E	855_V	0.588	0.29
68_M	782_P	0.587	0.29
693_D	821_P	0.587	0.29
20_K	35_F	0.587	0.29
415_S	483_T	0.586	0.29
266_H	365_P	0.586	0.29
552_G	556_S	0.585	0.29
773_A	779_Q	0.585	0.29
484_F	527_I	0.585	0.29
64_R	681_F	0.585	0.29
865_S	873_A	0.584	0.29
591_A	598_T	0.584	0.29
475_T	718_E	0.583	0.29
263_G	346_A	0.583	0.29
46_G	52_H	0.583	0.29
63_I	278_I	0.583	0.29
80_D	515_W	0.582	0.29
748_R	762_W	0.582	0.29
555_M	560_G	0.581	0.28
592_D	729_E	0.581	0.28
869_I	875_L	0.580	0.28
870_I	874_E	0.579	0.28
75_W	721_K	0.579	0.28
370_G	383_Y	0.579	0.28
287_Y	716_Y	0.578	0.28
82_A	277_K	0.578	0.28
579_E	844_L	0.577	0.28
428_Q	471_D	0.576	0.28
452_D	854_T	0.576	0.28
402_I	413_Y	0.576	0.28
238_E	294_A	0.576	0.28
19_E	743_L	0.576	0.28
35_F	65_Y	0.576	0.28
82_A	514_F	0.575	0.28
490_P	495_A	0.575	0.28
784_Y	788_Q	0.575	0.28
14_L	781_F	0.574	0.28
338_F	375_E	0.574	0.28
740_V	769_C	0.574	0.28
394_V	520_I	0.573	0.28
240_P	269_M	0.573	0.28
446_Y	454_V	0.573	0.28
26_P	32_Q	0.573	0.28
145_M	566_L	0.573	0.28
203_P	353_L	0.573	0.28
659_Q	736_R	0.572	0.28
492_N	496_L	0.572	0.28
109_A	114_I	0.572	0.28
584_N	594_I	0.572	0.28
233_V	263_G	0.572	0.28
586_M	598_T	0.572	0.28
52_H	60_D	0.571	0.28
37_I	59_M	0.571	0.28
428_Q	433_H	0.571	0.28
63_I	136_V	0.571	0.28
794_L	798_E	0.570	0.28
497_R	503_S	0.570	0.28
359_P	500_H	0.570	0.28
583_G	596_K	0.570	0.28
116_E	787_S	0.569	0.28
790_D	794_L	0.569	0.28
827_R	839_E	0.569	0.28
223_R	375_E	0.569	0.28
3_K	300_I	0.569	0.28
611_T	815_N	0.567	0.28
552_G	555_M	0.567	0.28
868_K	872_G	0.566	0.27
176_D	698_D	0.566	0.27
611_T	710_N	0.565	0.27
585_M	591_A	0.563	0.27
193_S	362_L	0.563	0.27
558_S	561_N	0.563	0.27
335_L	801_K	0.563	0.27
249_Y	263_G	0.562	0.27
200_I	229_G	0.562	0.27
864_V	877_I	0.562	0.27
13_P	17_H	0.562	0.27
41_P	80_D	0.561	0.27
425_I	435_I	0.560	0.27
412_M	522_M	0.560	0.27
679_A	790_D	0.560	0.27
809_N	812_A	0.560	0.27
386_A	420_I	0.559	0.27
217_L	246_I	0.559	0.27
423_W	431_W	0.559	0.27
868_K	875_L	0.558	0.27
592_D	604_N	0.558	0.27
296_P	308_R	0.558	0.27
399_N	725_N	0.558	0.27
167_Y	422_D	0.558	0.27
101_T	109_A	0.558	0.27
581_R	585_M	0.557	0.27
397_V	414_F	0.557	0.27
130_R	442_A	0.557	0.27
802_Q	805_V	0.556	0.27
88_M	121_S	0.556	0.27
798_E	801_K	0.556	0.27
119_A	123_G	0.556	0.27
204_L	250_V	0.556	0.27
204_L	748_R	0.556	0.27
390_A	521_M	0.556	0.27
14_L	23_Y	0.555	0.27
220_A	267_A	0.555	0.27
417_M	723_V	0.555	0.27
829_C	858_A	0.555	0.27
28_G	31_S	0.554	0.27
790_D	798_E	0.554	0.27
686_K	784_Y	0.554	0.27
238_E	792_A	0.554	0.27
677_I	717_L	0.554	0.27
571_G	605_G	0.554	0.27
838_N	858_A	0.553	0.27
805_V	812_A	0.553	0.27
289_V	339_A	0.553	0.27
797_T	801_K	0.552	0.27
743_L	794_L	0.552	0.27
696_R	699_I	0.552	0.27
197_M	364_V	0.552	0.27
508_G	614_L	0.552	0.27
185_D	509_F	0.552	0.27
266_H	547_I	0.552	0.27
446_Y	458_N	0.551	0.27
755_P	782_P	0.551	0.27
471_D	478_S	0.551	0.27
48_L	62_M	0.551	0.27
127_R	192_E	0.550	0.26
270_E	856_L	0.550	0.26
142_R	624_T	0.550	0.26
836_R	840_N	0.550	0.26
602_F	606_I	0.549	0.26
396_A	410_E	0.549	0.26
655_N	719_L	0.549	0.26
867_T	871_D	0.548	0.26
649_S	743_L	0.548	0.26
510_D	546_L	0.548	0.26
501_P	782_P	0.548	0.26
197_M	360_H	0.547	0.26
153_V	473_L	0.547	0.26
207_G	244_D	0.547	0.26
794_L	797_T	0.547	0.26
831_A	838_N	0.547	0.26
821_P	825_L	0.547	0.26
183_I	302_T	0.547	0.26
332_F	340_A	0.547	0.26
551_E	566_L	0.546	0.26
831_A	857_P	0.546	0.26
76_Q	482_W	0.546	0.26
188_V	473_L	0.546	0.26
722_P	821_P	0.546	0.26
282_H	424_C	0.546	0.26
781_F	819_G	0.546	0.26
176_D	368_D	0.545	0.26
152_A	156_V	0.545	0.26
428_Q	721_K	0.544	0.26
177_P	336_E	0.544	0.26
90_V	114_I	0.544	0.26
7_P	10_I	0.544	0.26
609_H	740_V	0.543	0.26
469_D	475_T	0.543	0.26
507_S	511_I	0.543	0.26
866_V	876_L	0.543	0.26
23_Y	65_Y	0.543	0.26
471_D	479_S	0.543	0.26
42_P	427_R	0.542	0.26
349_D	651_F	0.542	0.26
109_A	113_K	0.542	0.26
167_Y	405_V	0.542	0.26
101_T	105_Y	0.542	0.26
219_V	233_V	0.541	0.26
267_A	289_V	0.541	0.26
854_T	859_D	0.541	0.26
248_K	825_L	0.540	0.26
47_S	121_S	0.540	0.26
123_G	849_R	0.540	0.26
386_A	413_Y	0.540	0.26
670_L	674_D	0.540	0.26
433_H	478_S	0.540	0.26
67_R	73_T	0.540	0.26
365_P	674_D	0.539	0.26
809_N	864_V	0.539	0.26
33_E	265_E	0.539	0.26
437_A	469_D	0.539	0.26
590_L	598_T	0.539	0.26
36_C	93_K	0.539	0.26
426_S	432_G	0.539	0.26
14_L	544_T	0.538	0.26
802_Q	877_I	0.538	0.26
301_L	383_Y	0.538	0.26
657_E	662_G	0.538	0.26
503_S	540_T	0.538	0.26
108_E	112_D	0.538	0.26
367_G	374_I	0.537	0.26
859_D	862_G	0.537	0.26
386_A	389_L	0.537	0.26
299_N	377_M	0.537	0.26
50_M	121_S	0.536	0.26
139_E	238_E	0.536	0.26
172_L	276_V	0.536	0.26
252_L	362_L	0.535	0.25
552_G	561_N	0.534	0.25
525_H	534_P	0.534	0.25
99_G	795_A	0.533	0.25
116_E	119_A	0.533	0.25
566_L	611_T	0.533	0.25
225_E	341_R	0.533	0.25
405_V	499_F	0.533	0.25
469_D	478_S	0.533	0.25
175_W	253_P	0.532	0.25
674_D	679_A	0.531	0.25
667_E	704_L	0.531	0.25
756_F	760_T	0.531	0.25
579_E	583_G	0.531	0.25
230_D	279_T	0.531	0.25
233_V	374_I	0.530	0.25
395_E	822_L	0.530	0.25
428_Q	435_I	0.529	0.25
45_T	59_M	0.528	0.25
304_D	651_F	0.528	0.25
797_T	816_I	0.528	0.25
577_L	605_G	0.528	0.25
549_D	558_S	0.528	0.25
38_M	624_T	0.527	0.25
265_E	292_R	0.527	0.25
667_E	670_L	0.526	0.25
203_P	254_L	0.525	0.25
792_A	838_N	0.525	0.25
35_F	656_T	0.524	0.25
840_N	843_F	0.524	0.25
160_L	661_C	0.524	0.25
707_F	756_F	0.524	0.25
723_V	731_E	0.524	0.25
702_G	750_A	0.524	0.25
395_E	831_A	0.523	0.25
386_A	520_I	0.523	0.25
39_I	482_W	0.523	0.25
473_L	478_S	0.522	0.25
683_Q	789_V	0.522	0.25
108_E	434_R	0.522	0.25
509_F	546_L	0.522	0.25
220_A	271_K	0.522	0.25
339_A	342_K	0.522	0.25
423_W	427_R	0.521	0.25
66_Q	692_L	0.521	0.25
633_K	636_E	0.521	0.25
170_K	378_L	0.521	0.25
176_D	377_M	0.521	0.25
682_N	686_K	0.520	0.25
339_A	730_A	0.519	0.24
411_N	523_T	0.518	0.24
82_A	86_T	0.518	0.24
440_D	452_D	0.518	0.24
568_M	632_M	0.518	0.24
134_N	544_T	0.518	0.24
429_L	434_R	0.518	0.24
712_F	715_W	0.517	0.24
413_Y	417_M	0.516	0.24
789_V	794_L	0.516	0.24
136_V	149_L	0.516	0.24
77_V	89_V	0.516	0.24
348_V	534_P	0.515	0.24
331_E	335_L	0.515	0.24
687_A	691_A	0.515	0.24
146_D	237_P	0.515	0.24
279_T	519_M	0.515	0.24
75_W	138_W	0.514	0.24
190_N	364_V	0.514	0.24
200_I	351_L	0.513	0.24
115_W	143_F	0.513	0.24
772_T	784_Y	0.513	0.24
848_A	851_E	0.513	0.24
261_I	376_P	0.513	0.24
442_A	462_A	0.513	0.24
20_K	550_D	0.513	0.24
32_Q	780_P	0.513	0.24
503_S	539_H	0.513	0.24
620_A	638_Y	0.513	0.24
161_Y	457_E	0.513	0.24
447_V	450_N	0.513	0.24
523_T	535_Q	0.512	0.24
639_R	643_N	0.512	0.24
641_F	709_W	0.512	0.24
223_R	230_D	0.512	0.24
671_S	716_Y	0.512	0.24
91_E	114_I	0.512	0.24
38_M	505_M	0.511	0.24
683_Q	798_E	0.511	0.24
42_P	48_L	0.511	0.24
168_R	571_G	0.510	0.24
156_V	480_A	0.510	0.24
159_R	449_R	0.509	0.24
553_Q	590_L	0.509	0.24
231_T	250_V	0.509	0.24
257_R	438_W	0.509	0.24
574_L	578_L	0.509	0.24
524_M	593_K	0.509	0.24
831_A	841_R	0.507	0.24
399_N	875_L	0.507	0.24
4_T	645_L	0.507	0.24
475_T	518_R	0.507	0.24
165_L	570_D	0.507	0.24
436_P	755_P	0.506	0.24
5_Y	189_E	0.506	0.24
581_R	595_R	0.506	0.24
152_A	564_D	0.506	0.24
36_C	877_I	0.506	0.24
62_M	371_G	0.506	0.24
475_T	513_F	0.506	0.24
455_R	463_D	0.505	0.24
190_N	366_Y	0.505	0.24
726_G	729_E	0.504	0.24
549_D	554_K	0.504	0.24
282_H	381_Q	0.504	0.24
55_Q	58_I	0.504	0.24
197_M	220_A	0.504	0.24
816_I	824_L	0.504	0.24
227_L	234_A	0.503	0.24
162_K	844_L	0.503	0.24
522_M	732_L	0.503	0.24
842_G	858_A	0.503	0.24
137_D	453_E	0.502	0.23
386_A	590_L	0.502	0.23
18_W	24_F	0.502	0.23
189_E	412_M	0.502	0.23
779_Q	837_V	0.502	0.23
40_P	511_I	0.501	0.23
182_A	187_E	0.501	0.23
772_T	860_D	0.501	0.23
196_S	342_K	0.501	0.23
678_L	771_I	0.501	0.23
254_L	344_V	0.501	0.23
6_N	725_N	0.500	0.23
844_L	853_I	0.500	0.23
690_E	791_E	0.500	0.23
391_K	399_N	0.500	0.23

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1gaxA	1	0.8991	100	0.217	Contact Map
1ffyA	1	0.8665	100	0.303	Contact Map
1ileA	1	0.7886	100	0.373	Contact Map
1wz2A	1	0.8654	100	0.405	Contact Map
2v0cA	1	0.6688	100	0.467	Contact Map
1wkbA	1	0.714	100	0.469	Contact Map
4arcA	1	0.7077	100	0.484	Contact Map
3ziuA	1	0.6015	100	0.586	Contact Map
4qreA	1	0.53	100	0.682	Contact Map
1rqgA	2	0.5615	100	0.683	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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