PUTP - ECOLI - GREMLIN Contacts

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PUTP - Sodium/proline symporter

UniProt:	P07117	Sequences: MAISTPMLVTFCVYIFGMILIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWLLMGLPGAVFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEYNNNALTLPDYFTGRFEDKSRILRIISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATILYTFIGGFLAVSWTDTVQASLMIFALILTPVIVIISVGGFGDSLEVIKQKSIENVDMLKGLNFVAIISLMGWGLGYFGQPHILARFMAADSHHSIVHARRISMTWMILCLAGAVAVGFFGIAYFNDHPALAGAVNQNAERVFIELAQILFNPWIAGILLSAILAAVMSTLSCQLLVCSSAITEDLYKAFLRKHASQKELVWVGRVMVLVVALVAIALAANPENRVLGLVSYAWAGFGAAFGPVVLFSVMWSRMTRNGALAGMIIGALTVIVWKQFGWLGLYEIIPGFIFGSIGIVVFSLLGKAPSAAMQKRFAEADAHYHSAPPSRLQES	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10802
Length:	502 (458)
Sequences:	11508 (7250)
Seq/√Len:	338.8

ECOLI - PUTP ACTP PANF YIDK
BACSU - OPUE YWCA YCGO YODF YHJB
HALSA - Q9HR16 Q9HP63
SULSO - Q7LX83 Q97VX6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
436_I	465_G	5.853	1.00
367_S	370_E	4.105	1.00
425_M	466_I	3.914	1.00
263_S	266_S	3.772	1.00
363_R	370_E	3.589	1.00
172_I	383_A	3.334	1.00
436_I	461_F	3.326	1.00
20_L	24_I	3.313	1.00
358_Y	366_A	3.204	1.00
433_G	466_I	3.042	1.00
467_V	471_L	3.039	1.00
469_F	473_G	3.032	1.00
426_T	473_G	2.989	1.00
99_V	264_H	2.949	1.00
432_A	469_F	2.941	1.00
203_V	207_I	2.922	1.00
465_G	469_F	2.900	1.00
440_T	461_F	2.878	1.00
205_V	291_F	2.865	1.00
214_D	217_E	2.675	1.00
429_G	470_S	2.653	1.00
369_K	373_W	2.622	1.00
428_N	473_G	2.604	1.00
418_F	466_I	2.580	1.00
159_S	162_T	2.486	1.00
180_F	260_A	2.467	1.00
168_A	387_I	2.453	1.00
373_W	377_V	2.403	1.00
42_L	184_S	2.351	1.00
377_V	381_V	2.305	1.00
292_G	313_V	2.295	1.00
115_T	126_R	2.282	1.00
33_D	40_R	2.282	1.00
426_T	429_G	2.174	1.00
432_A	465_G	2.128	1.00
66_G	311_E	2.122	1.00
13_V	17_G	2.110	1.00
366_A	370_E	2.109	1.00
262_D	266_S	2.105	1.00
422_W	425_M	2.045	1.00
113_Y	419_S	2.040	1.00
384_L	388_A	1.959	1.00
58_G	147_A	1.948	1.00
34_D	39_G	1.939	1.00
165_W	169_A	1.933	1.00
426_T	470_S	1.927	1.00
429_G	469_F	1.923	1.00
428_N	432_A	1.922	1.00
37_L	40_R	1.911	1.00
118_F	425_M	1.910	1.00
415_V	430_A	1.901	1.00
214_D	218_V	1.892	1.00
197_A	333_A	1.882	1.00
16_F	20_L	1.881	1.00
363_R	366_A	1.875	1.00
199_I	203_V	1.862	1.00
296_F	320_I	1.861	1.00
217_E	221_Q	1.836	1.00
464_I	468_V	1.831	1.00
124_I	431_L	1.827	1.00
429_G	433_G	1.809	1.00
355_E	359_K	1.772	1.00
46_V	188_T	1.763	1.00
171_T	342_L	1.761	1.00
422_W	467_V	1.754	1.00
178_G	182_A	1.753	1.00
422_W	471_L	1.745	1.00
265_H	269_H	1.745	1.00
439_L	443_V	1.741	1.00
424_R	474_K	1.723	1.00
21_I	189_V	1.712	1.00
107_A	116_G	1.710	1.00
266_S	269_H	1.702	1.00
265_H	268_V	1.701	1.00
14_Y	18_M	1.695	1.00
373_W	376_R	1.687	1.00
358_Y	374_V	1.675	1.00
217_E	220_K	1.666	1.00
328_G	332_S	1.664	1.00
418_F	463_S	1.634	1.00
353_I	378_M	1.595	1.00
359_K	371_L	1.590	1.00
228_D	231_K	1.585	1.00
424_R	471_L	1.581	1.00
187_D	257_R	1.581	1.00
353_I	357_L	1.576	1.00
149_A	164_L	1.576	1.00
112_D	356_D	1.571	1.00
44_P	266_S	1.552	1.00
49_L	188_T	1.549	1.00
225_E	228_D	1.540	1.00
169_A	173_L	1.527	1.00
115_T	123_R	1.520	1.00
150_R	309_N	1.518	1.00
346_L	383_A	1.509	1.00
226_N	230_L	1.508	1.00
8_L	12_C	1.495	1.00
213_G	217_E	1.494	1.00
316_E	320_I	1.494	1.00
436_I	440_T	1.483	1.00
426_T	474_K	1.481	1.00
47_T	261_A	1.465	1.00
460_I	464_I	1.454	1.00
432_A	436_I	1.452	1.00
358_Y	363_R	1.439	1.00
17_G	21_I	1.438	1.00
161_E	391_A	1.423	1.00
119_E	124_I	1.404	1.00
366_A	371_L	1.388	1.00
370_E	373_W	1.382	1.00
18_M	189_V	1.380	1.00
223_S	227_V	1.378	1.00
119_E	427_R	1.371	1.00
187_D	343_S	1.369	1.00
7_M	325_W	1.363	1.00
132_V	438_A	1.356	1.00
93_V	417_L	1.349	1.00
27_R	30_K	1.341	1.00
12_C	16_F	1.340	1.00
164_L	387_I	1.340	1.00
349_C	382_V	1.340	1.00
171_T	339_M	1.333	1.00
168_A	383_A	1.327	1.00
224_I	229_M	1.320	1.00
162_T	166_A	1.309	1.00
112_D	355_E	1.307	1.00
228_D	232_G	1.298	1.00
218_V	221_Q	1.294	1.00
162_T	165_W	1.276	1.00
461_F	465_G	1.265	1.00
126_R	356_D	1.264	1.00
95_G	99_V	1.262	1.00
117_R	419_S	1.260	1.00
358_Y	370_E	1.260	1.00
131_L	135_L	1.256	1.00
36_I	375_G	1.254	1.00
223_S	226_N	1.251	1.00
186_T	343_S	1.245	1.00
372_V	376_R	1.244	1.00
400_L	404_A	1.243	1.00
123_R	360_A	1.241	1.00
190_Q	343_S	1.234	1.00
440_T	465_G	1.229	1.00
229_M	232_G	1.224	1.00
54_S	344_C	1.216	1.00
353_I	358_Y	1.210	1.00
209_V	215_S	1.208	1.00
148_G	167_G	1.206	1.00
115_T	360_A	1.200	1.00
94_A	98_R	1.196	1.00
145_I	168_A	1.196	1.00
424_R	475_A	1.190	1.00
161_E	165_W	1.182	1.00
113_Y	117_R	1.180	1.00
212_F	216_L	1.180	1.00
218_V	294_A	1.179	1.00
378_M	381_V	1.179	1.00
109_T	351_S	1.170	1.00
433_G	437_G	1.165	1.00
433_G	462_G	1.160	1.00
226_N	229_M	1.158	1.00
354_T	375_G	1.158	1.00
362_L	366_A	1.155	1.00
128_I	431_L	1.149	1.00
96_R	99_V	1.146	1.00
50_S	344_C	1.146	1.00
31_N	34_D	1.142	1.00
17_G	20_L	1.138	1.00
224_I	227_V	1.138	1.00
38_G	42_L	1.136	1.00
427_R	431_L	1.133	1.00
68_V	75_E	1.132	1.00
318_A	330_L	1.128	1.00
443_V	447_F	1.126	1.00
398_L	402_S	1.124	1.00
9_V	13_V	1.122	1.00
210_G	214_D	1.121	1.00
465_G	468_V	1.113	1.00
38_G	180_F	1.112	1.00
426_T	469_F	1.110	1.00
428_N	469_F	1.109	1.00
129_S	434_M	1.105	1.00
125_L	431_L	1.097	1.00
158_M	163_A	1.094	1.00
165_W	387_I	1.090	1.00
174_Y	339_M	1.088	1.00
187_D	344_C	1.084	1.00
463_S	467_V	1.083	1.00
192_S	196_F	1.072	1.00
460_I	463_S	1.070	1.00
425_M	429_G	1.068	1.00
131_L	357_L	1.068	1.00
224_I	230_L	1.067	1.00
375_G	379_V	1.063	1.00
224_I	228_D	1.060	1.00
153_E	160_Y	1.060	1.00
171_T	343_S	1.059	1.00
48_A	273_I	1.054	1.00
411_A	462_G	1.054	1.00
425_M	470_S	1.051	1.00
220_K	224_I	1.049	1.00
424_R	476_P	1.048	1.00
165_W	391_A	1.048	1.00
125_L	430_A	1.046	1.00
141_C	386_A	1.045	1.00
415_V	434_M	1.045	1.00
370_E	374_V	1.038	1.00
213_G	216_L	1.033	1.00
374_V	378_M	1.033	1.00
196_F	200_L	1.032	1.00
17_G	189_V	1.030	1.00
215_S	219_I	1.028	1.00
33_D	106_N	1.026	1.00
14_Y	339_M	1.022	1.00
142_A	389_L	1.021	1.00
397_V	401_V	1.020	1.00
114_F	129_S	1.015	1.00
9_V	12_C	1.014	1.00
200_L	204_I	1.011	1.00
211_G	214_D	1.011	1.00
29_T	34_D	1.011	1.00
52_G	277_W	1.010	1.00
54_S	187_D	1.006	1.00
419_S	430_A	1.006	1.00
128_I	434_M	1.004	1.00
225_E	229_M	1.004	1.00
6_P	9_V	1.002	1.00
368_Q	371_L	1.002	1.00
315_I	318_A	1.000	1.00
208_S	295_Y	0.996	1.00
174_Y	343_S	0.994	1.00
291_F	295_Y	0.994	1.00
366_A	374_V	0.993	1.00
44_P	48_A	0.993	1.00
50_S	53_A	0.988	1.00
105_N	116_G	0.987	1.00
235_F	238_I	0.982	1.00
118_F	419_S	0.975	1.00
124_I	128_I	0.974	1.00
353_I	382_V	0.973	1.00
307_N	310_A	0.973	1.00
429_G	432_A	0.971	1.00
216_L	220_K	0.971	1.00
118_F	466_I	0.968	1.00
223_S	230_L	0.966	1.00
145_I	164_L	0.961	1.00
388_A	392_N	0.955	1.00
418_F	425_M	0.955	1.00
354_T	374_V	0.955	1.00
190_Q	336_A	0.951	1.00
200_L	326_I	0.946	1.00
24_I	28_S	0.945	1.00
396_R	399_G	0.943	1.00
444_W	457_P	0.943	1.00
20_L	23_F	0.939	1.00
223_S	229_M	0.939	1.00
457_P	460_I	0.935	1.00
224_I	231_K	0.934	1.00
57_S	140_Y	0.933	1.00
123_R	127_I	0.930	1.00
19_I	22_G	0.921	1.00
36_I	351_S	0.917	1.00
309_N	312_R	0.912	1.00
153_E	157_G	0.912	1.00
455_I	459_F	0.907	1.00
81_G	85_G	0.906	1.00
114_F	125_L	0.903	1.00
50_S	184_S	0.902	1.00
340_S	343_S	0.902	1.00
58_G	338_V	0.901	1.00
174_Y	340_S	0.901	1.00
202_P	284_G	0.900	1.00
14_Y	336_A	0.900	1.00
83_T	279_I	0.896	1.00
70_L	310_A	0.896	1.00
176_F	380_L	0.895	1.00
402_S	405_W	0.894	1.00
384_L	387_I	0.892	1.00
402_S	406_A	0.891	1.00
347_L	350_S	0.890	1.00
19_I	23_F	0.889	1.00
426_T	475_A	0.888	1.00
215_S	291_F	0.887	1.00
216_L	219_I	0.885	1.00
428_N	472_L	0.884	1.00
174_Y	182_A	0.883	1.00
358_Y	362_L	0.883	1.00
198_L	285_A	0.882	1.00
140_Y	252_P	0.881	1.00
117_R	422_W	0.880	1.00
53_A	257_R	0.880	1.00
76_S	80_I	0.879	1.00
437_G	462_G	0.879	1.00
422_W	470_S	0.877	1.00
414_P	463_S	0.876	1.00
186_T	190_Q	0.876	1.00
174_Y	190_Q	0.876	1.00
136_F	407_G	0.873	1.00
381_V	385_V	0.873	1.00
443_V	446_Q	0.873	1.00
95_G	268_V	0.870	1.00
299_H	307_N	0.865	1.00
350_S	354_T	0.864	1.00
190_Q	340_S	0.863	1.00
435_I	439_L	0.861	1.00
132_V	434_M	0.860	1.00
288_V	317_L	0.858	1.00
134_L	353_I	0.857	1.00
50_S	257_R	0.852	1.00
6_P	10_T	0.851	1.00
124_I	427_R	0.849	1.00
15_I	18_M	0.849	1.00
437_G	441_V	0.849	1.00
316_E	319_Q	0.848	1.00
422_W	429_G	0.848	1.00
415_V	462_G	0.846	1.00
463_S	466_I	0.843	1.00
92_L	96_R	0.842	1.00
50_S	54_S	0.841	1.00
44_P	269_H	0.838	1.00
160_Y	164_L	0.834	1.00
225_E	230_L	0.833	1.00
43_G	266_S	0.832	1.00
292_G	317_L	0.831	1.00
261_A	267_I	0.829	1.00
38_G	260_A	0.828	1.00
401_V	405_W	0.828	1.00
397_V	402_S	0.827	1.00
29_T	372_V	0.825	1.00
461_F	464_I	0.824	1.00
53_A	190_Q	0.823	1.00
398_L	401_V	0.822	1.00
452_L	456_I	0.821	1.00
190_Q	341_T	0.818	1.00
61_L	330_L	0.814	1.00
85_G	89_N	0.812	1.00
164_L	390_A	0.810	1.00
218_V	222_K	0.809	1.00
49_L	191_A	0.806	1.00
46_V	184_S	0.805	1.00
227_V	231_K	0.804	1.00
227_V	230_L	0.803	1.00
358_Y	361_F	0.803	1.00
68_V	290_F	0.801	1.00
403_Y	445_K	0.800	1.00
379_V	383_A	0.799	1.00
418_F	467_V	0.799	1.00
69_F	298_D	0.798	1.00
200_L	203_V	0.798	1.00
23_F	177_I	0.795	1.00
183_V	186_T	0.794	1.00
19_I	173_L	0.794	1.00
11_F	335_L	0.790	1.00
127_I	361_F	0.789	1.00
91_K	272_R	0.787	1.00
88_I	92_L	0.787	1.00
233_L	236_V	0.785	1.00
24_I	27_R	0.784	1.00
468_V	472_L	0.783	1.00
201_T	205_V	0.781	1.00
128_I	435_I	0.781	1.00
437_G	440_T	0.780	1.00
60_L	282_L	0.779	1.00
98_R	264_H	0.777	1.00
61_L	198_L	0.776	1.00
23_F	27_R	0.775	1.00
397_V	400_L	0.774	1.00
23_F	26_W	0.774	1.00
431_L	435_I	0.774	1.00
220_K	223_S	0.773	1.00
422_W	426_T	0.772	1.00
318_A	327_A	0.771	1.00
124_I	127_I	0.769	1.00
312_R	316_E	0.769	1.00
448_G	451_G	0.766	1.00
272_R	276_T	0.766	1.00
226_N	231_K	0.765	1.00
362_L	365_H	0.765	1.00
425_M	433_G	0.762	1.00
462_G	466_I	0.761	1.00
165_W	384_L	0.759	1.00
67_A	71_S	0.758	1.00
158_M	166_A	0.758	1.00
83_T	275_M	0.756	1.00
359_K	364_K	0.754	1.00
440_T	444_W	0.753	1.00
215_S	218_V	0.753	1.00
204_I	208_S	0.753	1.00
7_M	10_T	0.753	1.00
13_V	20_L	0.747	1.00
377_V	380_L	0.747	1.00
123_R	126_R	0.747	1.00
276_T	280_L	0.746	1.00
440_T	443_V	0.745	1.00
163_A	167_G	0.742	0.99
371_L	375_G	0.741	0.99
134_L	349_C	0.740	0.99
358_Y	364_K	0.740	0.99
44_P	273_I	0.740	0.99
430_A	437_G	0.739	0.99
7_M	327_A	0.738	0.99
94_A	97_L	0.738	0.99
57_S	61_L	0.736	0.99
10_T	325_W	0.733	0.99
201_T	314_F	0.732	0.99
24_I	185_W	0.731	0.99
11_F	15_I	0.730	0.99
468_V	471_L	0.728	0.99
180_F	184_S	0.727	0.99
78_I	81_G	0.727	0.99
111_P	129_S	0.727	0.99
418_F	422_W	0.726	0.99
185_W	188_T	0.726	0.99
90_W	94_A	0.725	0.99
209_V	214_D	0.725	0.99
388_A	391_A	0.723	0.99
438_A	442_I	0.721	0.99
208_S	321_L	0.720	0.99
428_N	474_K	0.717	0.99
25_A	185_W	0.717	0.99
183_V	344_C	0.716	0.99
223_S	228_D	0.715	0.99
144_G	342_L	0.714	0.99
225_E	231_K	0.713	0.99
50_S	187_D	0.712	0.99
195_I	199_I	0.711	0.99
190_Q	339_M	0.711	0.99
63_G	140_Y	0.709	0.99
111_P	133_I	0.709	0.99
354_T	371_L	0.709	0.99
10_T	328_G	0.709	0.99
69_F	299_H	0.708	0.99
92_L	95_G	0.707	0.99
206_I	287_A	0.706	0.99
261_A	266_S	0.706	0.99
467_V	470_S	0.702	0.99
183_V	257_R	0.699	0.99
14_Y	190_Q	0.699	0.99
353_I	374_V	0.696	0.99
209_V	294_A	0.694	0.99
436_I	469_F	0.694	0.99
227_V	232_G	0.694	0.99
206_I	211_G	0.691	0.99
341_T	345_Q	0.691	0.99
7_M	328_G	0.689	0.99
42_L	47_T	0.688	0.99
94_A	267_I	0.685	0.99
73_I	290_F	0.684	0.99
78_I	82_L	0.683	0.99
150_R	311_E	0.683	0.99
413_G	417_L	0.683	0.99
55_D	405_W	0.681	0.99
474_K	477_S	0.681	0.99
345_Q	348_V	0.679	0.99
119_E	477_S	0.678	0.99
350_S	378_M	0.678	0.99
346_L	379_V	0.677	0.99
235_F	239_I	0.676	0.99
149_A	160_Y	0.676	0.99
26_W	177_I	0.675	0.99
144_G	341_T	0.674	0.99
119_E	125_L	0.674	0.99
207_I	212_F	0.673	0.99
456_I	460_I	0.671	0.99
222_K	226_N	0.668	0.99
175_T	343_S	0.666	0.99
453_Y	457_P	0.664	0.99
148_G	338_V	0.663	0.99
472_L	475_A	0.663	0.99
79_A	86_A	0.663	0.99
152_F	163_A	0.663	0.99
247_G	252_P	0.661	0.99
25_A	29_T	0.659	0.99
317_L	321_L	0.657	0.99
312_R	315_I	0.656	0.99
35_Y	376_R	0.656	0.99
45_F	49_L	0.654	0.99
34_D	181_L	0.652	0.99
95_G	264_H	0.651	0.99
424_R	427_R	0.651	0.99
187_D	340_S	0.650	0.99
387_I	391_A	0.648	0.99
234_N	237_A	0.648	0.99
475_A	478_A	0.647	0.99
95_G	98_R	0.646	0.99
210_G	213_G	0.646	0.99
459_F	462_G	0.645	0.99
469_F	472_L	0.644	0.99
35_Y	379_V	0.642	0.99
127_I	130_A	0.642	0.99
118_F	418_F	0.641	0.98
269_H	273_I	0.641	0.98
112_D	116_G	0.640	0.98
454_E	458_G	0.639	0.98
145_I	182_A	0.638	0.98
33_D	368_Q	0.637	0.98
150_R	153_E	0.636	0.98
127_I	131_L	0.635	0.98
45_F	188_T	0.635	0.98
85_G	245_G	0.634	0.98
325_W	329_I	0.633	0.98
204_I	207_I	0.632	0.98
54_S	257_R	0.632	0.98
458_G	462_G	0.631	0.98
387_I	390_A	0.631	0.98
253_H	256_A	0.631	0.98
190_Q	337_A	0.630	0.98
235_F	240_S	0.629	0.98
172_I	380_L	0.628	0.98
57_S	144_G	0.627	0.98
108_L	112_D	0.623	0.98
172_I	176_F	0.622	0.98
441_V	458_G	0.622	0.98
434_M	437_G	0.622	0.98
55_D	82_L	0.622	0.98
296_F	299_H	0.621	0.98
322_F	326_I	0.620	0.98
28_S	181_L	0.620	0.98
109_T	356_D	0.619	0.98
69_F	313_V	0.616	0.98
183_V	347_L	0.616	0.98
168_A	390_A	0.612	0.98
293_I	313_V	0.612	0.98
164_L	168_A	0.611	0.98
350_S	379_V	0.609	0.98
206_I	210_G	0.608	0.98
428_N	431_L	0.608	0.98
439_L	442_I	0.608	0.98
222_K	293_I	0.607	0.98
401_V	404_A	0.606	0.98
146_V	150_R	0.606	0.98
350_S	375_G	0.606	0.98
236_V	240_S	0.604	0.98
414_P	466_I	0.603	0.98
275_M	279_I	0.603	0.98
10_T	332_S	0.602	0.98
32_F	36_I	0.602	0.98
241_L	244_W	0.602	0.98
29_T	181_L	0.600	0.98
96_R	421_M	0.598	0.98
43_G	46_V	0.598	0.98
359_K	368_Q	0.597	0.98
43_G	47_T	0.595	0.98
206_I	212_F	0.594	0.98
53_A	191_A	0.592	0.97
248_Y	252_P	0.591	0.97
288_V	314_F	0.591	0.97
257_R	344_C	0.590	0.97
126_R	130_A	0.590	0.97
199_I	202_P	0.590	0.97
224_I	232_G	0.588	0.97
223_S	231_K	0.586	0.97
74_S	77_W	0.585	0.97
257_R	340_S	0.585	0.97
141_C	342_L	0.585	0.97
118_F	430_A	0.584	0.97
47_T	50_S	0.584	0.97
246_L	413_G	0.583	0.97
61_L	66_G	0.582	0.97
133_I	352_A	0.582	0.97
206_I	215_S	0.582	0.97
430_A	433_G	0.582	0.97
293_I	297_N	0.581	0.97
473_G	476_P	0.581	0.97
398_L	406_A	0.581	0.97
401_V	406_A	0.580	0.97
174_Y	178_G	0.580	0.97
55_D	278_M	0.580	0.97
424_R	428_N	0.579	0.97
223_S	232_G	0.579	0.97
181_L	185_W	0.578	0.97
22_G	26_W	0.578	0.97
337_A	340_S	0.578	0.97
153_E	159_S	0.576	0.97
244_W	247_G	0.575	0.97
445_K	454_E	0.575	0.97
140_Y	345_Q	0.574	0.97
339_M	343_S	0.574	0.97
295_Y	317_L	0.573	0.97
67_A	75_E	0.573	0.97
198_L	284_G	0.571	0.97
6_P	324_P	0.571	0.97
429_G	465_G	0.570	0.97
144_G	147_A	0.570	0.97
187_D	190_Q	0.569	0.97
205_V	321_L	0.569	0.97
244_W	248_Y	0.569	0.97
422_W	472_L	0.569	0.97
272_R	275_M	0.568	0.97
205_V	208_S	0.568	0.97
397_V	405_W	0.568	0.97
54_S	175_T	0.567	0.97
55_D	401_V	0.567	0.97
52_G	191_A	0.565	0.97
245_G	252_P	0.565	0.97
215_S	294_A	0.565	0.97
48_A	52_G	0.564	0.97
40_R	98_R	0.564	0.97
184_S	187_D	0.564	0.97
97_L	255_L	0.563	0.97
202_P	287_A	0.563	0.97
464_I	467_V	0.562	0.97
32_F	371_L	0.562	0.97
114_F	415_V	0.561	0.97
87_W	91_K	0.561	0.97
52_G	281_C	0.560	0.97
406_A	441_V	0.560	0.97
432_A	435_I	0.560	0.97
380_L	384_L	0.559	0.96
46_V	185_W	0.558	0.96
62_M	147_A	0.558	0.96
140_Y	144_G	0.557	0.96
81_G	86_A	0.556	0.96
226_N	232_G	0.556	0.96
201_T	330_L	0.555	0.96
125_L	129_S	0.554	0.96
127_I	357_L	0.553	0.96
7_M	22_G	0.552	0.96
196_F	199_I	0.551	0.96
307_N	316_E	0.550	0.96
54_S	253_H	0.550	0.96
433_G	436_I	0.549	0.96
345_Q	412_F	0.549	0.96
258_F	271_R	0.548	0.96
169_A	380_L	0.547	0.96
18_M	22_G	0.547	0.96
442_I	446_Q	0.546	0.96
42_L	260_A	0.544	0.96
110_L	416_V	0.544	0.96
365_H	370_E	0.541	0.96
449_W	457_P	0.538	0.96
352_A	356_D	0.537	0.96
432_A	473_G	0.535	0.95
132_V	411_A	0.535	0.95
426_T	430_A	0.534	0.95
219_I	222_K	0.532	0.95
286_V	290_F	0.531	0.95
79_A	82_L	0.531	0.95
209_V	218_V	0.531	0.95
84_L	242_M	0.529	0.95
201_T	318_A	0.529	0.95
146_V	160_Y	0.528	0.95
353_I	381_V	0.527	0.95
117_R	423_S	0.527	0.95
133_I	412_F	0.527	0.95
59_W	405_W	0.527	0.95
354_T	358_Y	0.526	0.95
243_G	252_P	0.526	0.95
43_G	185_W	0.525	0.95
262_D	265_H	0.523	0.95
87_W	272_R	0.523	0.95
94_A	264_H	0.522	0.95
233_L	237_A	0.522	0.95
107_A	112_D	0.521	0.95
165_W	168_A	0.520	0.95
324_P	327_A	0.520	0.95
140_Y	405_W	0.520	0.95
30_K	34_D	0.520	0.95
15_I	19_I	0.520	0.95
214_D	294_A	0.519	0.95
125_L	427_R	0.519	0.95
385_V	388_A	0.518	0.95
28_S	41_S	0.515	0.94
310_A	313_V	0.515	0.94
56_M	274_S	0.515	0.94
186_T	257_R	0.514	0.94
459_F	463_S	0.514	0.94
77_W	81_G	0.514	0.94
66_G	310_A	0.514	0.94
319_Q	327_A	0.512	0.94
59_W	140_Y	0.511	0.94
68_V	289_G	0.509	0.94
21_I	25_A	0.509	0.94
376_R	379_V	0.508	0.94
126_R	360_A	0.507	0.94
129_S	133_I	0.506	0.94
67_A	70_L	0.506	0.94
150_R	154_S	0.505	0.94
425_M	430_A	0.504	0.94
294_A	297_N	0.503	0.94
204_I	321_L	0.503	0.94
361_F	364_K	0.503	0.94
365_H	377_V	0.502	0.94
165_W	390_A	0.501	0.94
399_G	402_S	0.501	0.94
424_R	470_S	0.501	0.94
243_G	413_G	0.500	0.94

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2xq2A	2	0.9243	100	0.234	Contact Map
3dh4A	3	0.8805	100	0.277	Contact Map
3l1lA	2	0.8028	99.3	0.857	Contact Map
3giaA	1	0.8347	99.3	0.858	Contact Map
4wgvA	2	0.7291	99.1	0.874	Contact Map
2jlnA	1	0.8227	99	0.878	Contact Map
4djkA	2	0.7988	98.8	0.885	Contact Map
4c7rA	3	0.8426	97.5	0.918	Contact Map
2wswA	3	0.7948	95.8	0.934	Contact Map
4us3A	1	0.7809	95.4	0.936	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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