MCP2 - ECOLI - GREMLIN Contacts

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MCP2 - Methyl-accepting chemotaxis protein II

UniProt:	P07017	Sequences: MINRIRVVTLLVMVLGVFALLQLISGSLFFSSLHHSQKSFVVSNQLREQQGELTSTWDLMLQTRINLSRSAVRMMMDSSNQQSNAKVELLDSARKTLAQAATHYKKFKSMAPLPEMVATSRNIDEKYKNYYTALTELIDYLDYGNTGAYFAQPTQGMQNAMGEAFAQYALSSEKLYRDIVTDNADDYRFAQWQLAVIALVVVLILLVAWYGIRRMLLTPLAKIIAHIREIAGGNLANTLTIDGRSEMGDLAQSVSHMQRSLTDTVTHVREGSDAIYAGTREIAAGNTDLSSRTEQQASALEETAASMEQLTATVKQNADNARQASQLAQSASDTAQHGGKVVDGVVKTMHEIADSSKKIADIISVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRNLASRSAQAAKEIKALIEDSVSRVDTGSVLVESAGETMNNIVNAVTRVTDIMGEIASASDEQSRGIDQVALAVSEMDRVTQQNASLVQESAAAAAALEEQASRLTQAVSAFRLAASPLTNKPQTPSRPASEQPPAQPRLRIAEQDPNWETF	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10988
Length:	553 (504)
Sequences:	19963 (17191)
Seq/√Len:	765.7

ECOLI - MCP2 MCP1 MCP3 MCP4 AER
BACSU - YVAQ TLPB YOAH MCPB MCPA TLPA TLPC MCPC HEMAT
HALSA - HTR4 Q9HRA1 HTR2 COST Q9HQX8 HMAT HTR7 Q9HPA2 Q9HP10 HTR9 Q9HS86 Q9HR88 Q9HRN6 Q9HPQ5 Q9HQT5 HTR1 Q9HPW6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
243_G	248_G	3.582	1.00
335_A	338_G	3.582	1.00
6_R	9_T	3.330	1.00
229_E	234_N	3.152	1.00
145_N	148_A	2.646	1.00
229_E	237_N	2.482	1.00
351_E	425_R	2.434	1.00
27_S	31_S	2.409	1.00
10_L	245_S	2.326	1.00
328_A	338_G	2.279	1.00
238_T	262_T	2.271	1.00
192_W	196_V	2.270	1.00
355_S	425_R	2.268	1.00
224_I	249_D	2.266	1.00
333_D	337_H	2.220	1.00
255_S	258_Q	2.165	1.00
214_R	218_T	2.154	1.00
228_R	249_D	2.152	1.00
228_R	256_H	2.104	1.00
267_H	505_R	2.090	1.00
354_D	357_K	2.086	1.00
358_K	361_D	2.073	1.00
223_I	251_A	2.059	1.00
355_S	421_D	2.039	1.00
139_D	143_Y	2.013	1.00
224_I	253_S	1.996	1.00
189_F	193_Q	1.989	1.00
340_K	344_G	1.970	1.00
213_R	217_L	1.955	1.00
316_Q	319_D	1.946	1.00
255_S	259_R	1.938	1.00
108_K	124_D	1.936	1.00
227_I	257_M	1.904	1.00
228_R	232_G	1.886	1.00
498_A	501_E	1.873	1.00
364_S	368_G	1.849	1.00
427_D	431_V	1.838	1.00
245_S	248_G	1.835	1.00
230_I	257_M	1.829	1.00
227_I	254_V	1.825	1.00
188_R	192_W	1.819	1.00
136_E	139_D	1.801	1.00
238_T	259_R	1.792	1.00
330_S	333_D	1.787	1.00
230_I	258_Q	1.776	1.00
361_D	364_S	1.756	1.00
416_K	420_E	1.750	1.00
353_A	430_S	1.723	1.00
360_A	423_V	1.723	1.00
26_G	198_A	1.717	1.00
287_T	291_S	1.715	1.00
121_R	125_E	1.714	1.00
351_E	354_D	1.687	1.00
238_T	255_S	1.681	1.00
470_Q	473_L	1.667	1.00
249_D	252_Q	1.664	1.00
135_T	139_D	1.655	1.00
431_V	435_S	1.648	1.00
449_R	452_D	1.647	1.00
228_R	253_S	1.646	1.00
101_A	105_K	1.628	1.00
10_L	215_M	1.619	1.00
326_Q	330_S	1.619	1.00
477_E	480_R	1.617	1.00
329_Q	333_D	1.615	1.00
347_K	350_H	1.615	1.00
91_D	95_K	1.607	1.00
410_Q	414_E	1.605	1.00
443_I	454_M	1.603	1.00
408_S	412_A	1.599	1.00
118_A	122_N	1.598	1.00
195_A	199_L	1.594	1.00
505_R	508_Q	1.591	1.00
196_V	200_V	1.587	1.00
440_M	443_I	1.585	1.00
340_K	343_D	1.583	1.00
170_L	174_K	1.583	1.00
102_T	106_K	1.580	1.00
163_E	167_Q	1.578	1.00
448_T	452_D	1.573	1.00
321_A	324_A	1.565	1.00
326_Q	329_Q	1.564	1.00
87_V	91_D	1.556	1.00
238_T	258_Q	1.548	1.00
438_E	442_N	1.546	1.00
504_S	508_Q	1.534	1.00
57_W	60_M	1.523	1.00
406_S	410_Q	1.523	1.00
501_E	505_R	1.523	1.00
223_I	250_L	1.520	1.00
403_N	406_S	1.520	1.00
263_D	267_H	1.517	1.00
323_Q	326_Q	1.517	1.00
277_A	281_E	1.506	1.00
469_D	473_L	1.501	1.00
262_T	266_T	1.501	1.00
28_L	32_S	1.487	1.00
348_T	428_T	1.485	1.00
420_E	424_S	1.484	1.00
367_D	416_K	1.482	1.00
438_E	441_N	1.481	1.00
334_T	442_N	1.459	1.00
358_K	414_E	1.456	1.00
89_L	92_S	1.455	1.00
413_K	417_A	1.451	1.00
288_D	291_S	1.449	1.00
227_I	253_S	1.437	1.00
122_N	126_K	1.435	1.00
356_S	426_V	1.432	1.00
491_E	494_A	1.426	1.00
181_T	185_D	1.422	1.00
136_E	140_Y	1.422	1.00
188_R	191_Q	1.421	1.00
105_K	109_S	1.414	1.00
61_L	64_R	1.405	1.00
191_Q	195_A	1.404	1.00
354_D	358_K	1.402	1.00
487_S	491_E	1.400	1.00
442_N	445_N	1.392	1.00
445_N	449_R	1.389	1.00
18_F	205_L	1.386	1.00
84_N	88_E	1.382	1.00
298_S	302_E	1.381	1.00
105_K	108_K	1.380	1.00
224_I	228_R	1.375	1.00
88_E	91_D	1.375	1.00
302_E	305_A	1.372	1.00
350_H	354_D	1.364	1.00
507_T	511_S	1.361	1.00
138_I	142_D	1.360	1.00
319_D	323_Q	1.358	1.00
441_N	445_N	1.347	1.00
299_A	477_E	1.347	1.00
221_A	224_I	1.343	1.00
8_V	12_V	1.342	1.00
117_V	121_R	1.339	1.00
139_D	142_D	1.339	1.00
308_E	312_A	1.323	1.00
410_Q	413_K	1.319	1.00
424_S	428_T	1.309	1.00
480_R	484_Q	1.309	1.00
355_S	358_K	1.308	1.00
241_I	255_S	1.306	1.00
350_H	434_E	1.303	1.00
298_S	301_E	1.303	1.00
177_R	181_T	1.302	1.00
462_D	466_R	1.301	1.00
180_V	184_A	1.301	1.00
322_R	326_Q	1.298	1.00
234_N	237_N	1.296	1.00
223_I	254_V	1.295	1.00
260_S	512_A	1.287	1.00
332_S	336_Q	1.277	1.00
174_K	178_D	1.275	1.00
269_R	273_D	1.265	1.00
125_E	129_N	1.264	1.00
209_W	213_R	1.262	1.00
24_I	28_L	1.262	1.00
497_A	501_E	1.262	1.00
353_A	427_D	1.261	1.00
115_E	118_A	1.261	1.00
92_S	96_T	1.259	1.00
187_Y	191_Q	1.259	1.00
309_Q	312_A	1.259	1.00
192_W	195_A	1.258	1.00
173_E	177_R	1.252	1.00
324_A	454_M	1.246	1.00
292_R	481_V	1.245	1.00
124_D	128_K	1.241	1.00
450_V	454_M	1.240	1.00
227_I	250_L	1.238	1.00
69_R	73_R	1.236	1.00
399_G	402_R	1.236	1.00
349_M	429_G	1.234	1.00
381_A	399_G	1.232	1.00
229_E	232_G	1.228	1.00
270_E	274_A	1.226	1.00
259_R	263_D	1.224	1.00
232_G	256_H	1.224	1.00
41_V	45_Q	1.222	1.00
431_V	434_E	1.221	1.00
487_S	490_Q	1.221	1.00
133_A	136_E	1.219	1.00
222_K	240_T	1.218	1.00
490_Q	494_A	1.217	1.00
267_H	509_A	1.214	1.00
358_K	421_D	1.214	1.00
270_E	273_D	1.213	1.00
328_A	331_A	1.212	1.00
84_N	87_V	1.211	1.00
328_A	335_A	1.206	1.00
179_I	182_D	1.206	1.00
154_T	158_Q	1.205	1.00
414_E	417_A	1.200	1.00
225_A	228_R	1.197	1.00
284_A	288_D	1.197	1.00
241_I	251_A	1.194	1.00
357_K	427_D	1.194	1.00
8_V	214_R	1.193	1.00
90_L	93_A	1.192	1.00
509_A	512_A	1.190	1.00
6_R	249_D	1.190	1.00
348_T	429_G	1.188	1.00
347_K	351_E	1.188	1.00
122_N	125_E	1.187	1.00
260_S	263_D	1.185	1.00
351_E	355_S	1.183	1.00
239_L	255_S	1.183	1.00
5_I	9_T	1.181	1.00
32_S	35_H	1.181	1.00
62_Q	65_I	1.180	1.00
74_M	77_D	1.179	1.00
116_M	119_T	1.175	1.00
226_H	239_L	1.175	1.00
480_R	483_Q	1.175	1.00
119_T	123_I	1.172	1.00
222_K	225_A	1.166	1.00
365_V	411_A	1.166	1.00
291_S	295_Q	1.163	1.00
333_D	336_Q	1.163	1.00
280_R	284_A	1.158	1.00
353_A	357_K	1.154	1.00
140_Y	145_N	1.150	1.00
193_Q	196_V	1.149	1.00
164_A	167_Q	1.145	1.00
106_K	109_S	1.145	1.00
443_I	450_V	1.141	1.00
31_S	35_H	1.139	1.00
499_L	513_F	1.137	1.00
153_P	156_G	1.131	1.00
291_S	294_E	1.126	1.00
152_Q	156_G	1.126	1.00
334_T	337_H	1.124	1.00
223_I	227_I	1.124	1.00
436_A	440_M	1.120	1.00
29_F	194_L	1.117	1.00
72_V	76_M	1.117	1.00
315_K	319_D	1.117	1.00
92_S	95_K	1.116	1.00
295_Q	298_S	1.115	1.00
37_Q	187_Y	1.113	1.00
102_T	105_K	1.112	1.00
417_A	421_D	1.106	1.00
281_E	284_A	1.105	1.00
337_H	340_K	1.098	1.00
56_T	59_L	1.096	1.00
413_K	416_K	1.094	1.00
483_Q	487_S	1.093	1.00
221_A	249_D	1.092	1.00
68_S	72_V	1.092	1.00
334_T	338_G	1.090	1.00
207_V	211_G	1.087	1.00
294_E	298_S	1.086	1.00
508_Q	511_S	1.080	1.00
428_T	431_V	1.079	1.00
128_K	132_T	1.071	1.00
29_F	33_L	1.068	1.00
341_V	346_V	1.066	1.00
273_D	277_A	1.066	1.00
222_K	226_H	1.065	1.00
172_S	175_L	1.064	1.00
221_A	225_A	1.058	1.00
121_R	124_D	1.057	1.00
476_S	480_R	1.056	1.00
421_D	425_R	1.055	1.00
7_V	247_M	1.054	1.00
65_I	69_R	1.052	1.00
174_K	177_R	1.051	1.00
319_D	322_R	1.050	1.00
118_A	121_R	1.049	1.00
344_G	347_K	1.047	1.00
114_P	117_V	1.046	1.00
331_A	338_G	1.044	1.00
88_E	92_S	1.042	1.00
317_N	461_S	1.041	1.00
85_A	88_E	1.038	1.00
8_V	213_R	1.038	1.00
83_S	87_V	1.036	1.00
64_R	68_S	1.033	1.00
258_Q	262_T	1.029	1.00
463_E	466_R	1.025	1.00
343_D	347_K	1.024	1.00
99_Q	102_T	1.024	1.00
26_G	30_F	1.022	1.00
126_K	129_N	1.021	1.00
132_T	135_T	1.019	1.00
166_A	170_L	1.019	1.00
58_D	62_Q	1.017	1.00
481_V	485_N	1.017	1.00
66_N	69_R	1.016	1.00
217_L	221_A	1.016	1.00
185_D	189_F	1.015	1.00
409_A	413_K	1.014	1.00
352_I	429_G	1.014	1.00
8_V	217_L	1.012	1.00
251_A	255_S	1.010	1.00
362_I	418_L	1.009	1.00
30_F	34_H	1.009	1.00
484_Q	487_S	1.009	1.00
358_K	418_L	1.006	1.00
83_S	86_K	1.006	1.00
367_D	412_A	1.005	1.00
501_E	504_S	1.005	1.00
256_H	259_R	1.004	1.00
273_D	507_T	1.003	1.00
161_M	164_A	1.002	1.00
336_Q	340_K	0.996	1.00
145_N	149_Y	0.995	1.00
210_Y	214_R	0.994	1.00
19_A	205_L	0.993	1.00
341_V	435_S	0.993	1.00
178_D	182_D	0.992	1.00
74_M	78_S	0.989	1.00
132_T	136_E	0.988	1.00
67_L	70_S	0.986	1.00
134_L	138_I	0.985	1.00
35_H	39_S	0.985	1.00
381_A	402_R	0.984	1.00
348_T	432_L	0.984	1.00
64_R	67_L	0.983	1.00
67_L	71_A	0.982	1.00
12_V	16_G	0.982	1.00
312_A	316_Q	0.979	1.00
466_R	470_Q	0.974	1.00
206_L	210_Y	0.973	1.00
224_I	250_L	0.970	1.00
367_D	371_F	0.970	1.00
339_G	343_D	0.968	1.00
267_H	270_E	0.967	1.00
407_R	410_Q	0.967	1.00
466_R	469_D	0.966	1.00
504_S	507_T	0.965	1.00
90_L	94_R	0.964	1.00
473_L	477_E	0.964	1.00
252_Q	255_S	0.962	1.00
21_L	201_V	0.961	1.00
160_A	163_E	0.957	1.00
494_A	498_A	0.957	1.00
72_V	77_D	0.954	1.00
225_A	229_E	0.954	1.00
159_N	163_E	0.953	1.00
241_I	252_Q	0.953	1.00
417_A	420_E	0.953	1.00
141_L	145_N	0.951	1.00
508_Q	512_A	0.948	1.00
63_T	66_N	0.948	1.00
184_A	188_R	0.947	1.00
60_M	64_R	0.945	1.00
199_L	203_L	0.943	1.00
274_A	498_A	0.941	1.00
295_Q	299_A	0.929	1.00
459_S	463_E	0.927	1.00
15_L	209_W	0.926	1.00
327_L	331_A	0.926	1.00
168_Y	172_S	0.925	1.00
256_H	260_S	0.925	1.00
324_A	338_G	0.924	1.00
120_S	124_D	0.923	1.00
85_A	89_L	0.921	1.00
73_R	76_M	0.920	1.00
226_H	237_N	0.920	1.00
322_R	462_D	0.918	1.00
325_S	329_Q	0.917	1.00
235_L	261_L	0.915	1.00
437_G	441_N	0.915	1.00
230_I	254_V	0.915	1.00
368_G	407_R	0.913	1.00
284_A	287_T	0.913	1.00
34_H	191_Q	0.912	1.00
239_L	251_A	0.912	1.00
97_L	100_A	0.912	1.00
244_R	248_G	0.911	1.00
215_M	219_P	0.907	1.00
226_H	229_E	0.907	1.00
219_P	243_G	0.907	1.00
220_L	250_L	0.904	1.00
315_K	469_D	0.904	1.00
71_A	74_M	0.903	1.00
156_G	160_A	0.903	1.00
510_V	513_F	0.903	1.00
247_M	251_A	0.902	1.00
276_Y	280_R	0.902	1.00
61_L	65_I	0.899	1.00
70_S	73_R	0.898	1.00
341_V	344_G	0.892	1.00
125_E	128_K	0.892	1.00
445_N	448_T	0.890	1.00
266_T	270_E	0.886	1.00
436_A	443_I	0.885	1.00
189_F	192_W	0.884	1.00
470_Q	474_A	0.882	1.00
155_Q	159_N	0.881	1.00
424_S	427_D	0.881	1.00
306_S	309_Q	0.879	1.00
127_Y	130_Y	0.879	1.00
169_A	172_S	0.879	1.00
305_A	309_Q	0.878	1.00
211_G	214_R	0.878	1.00
108_K	111_A	0.878	1.00
229_E	257_M	0.878	1.00
114_P	118_A	0.876	1.00
54_T	58_D	0.873	1.00
336_Q	448_T	0.871	1.00
268_V	510_V	0.870	1.00
141_L	144_G	0.869	1.00
452_D	455_G	0.869	1.00
218_T	222_K	0.865	1.00
60_M	68_S	0.865	1.00
459_S	462_D	0.864	1.00
59_L	62_Q	0.863	1.00
65_I	68_S	0.862	1.00
115_E	119_T	0.860	1.00
32_S	36_S	0.858	1.00
218_T	221_A	0.856	1.00
473_L	476_S	0.855	1.00
240_T	255_S	0.854	1.00
58_D	61_L	0.853	1.00
40_F	43_S	0.853	1.00
241_I	245_S	0.852	1.00
368_G	371_F	0.846	1.00
113_L	116_M	0.844	1.00
352_I	422_S	0.843	1.00
288_D	292_R	0.842	1.00
119_T	122_N	0.838	1.00
456_E	459_S	0.838	1.00
351_E	428_T	0.837	1.00
339_G	346_V	0.836	1.00
220_L	247_M	0.835	1.00
467_G	471_V	0.833	1.00
440_M	454_M	0.825	1.00
332_S	335_A	0.823	1.00
86_K	89_L	0.823	1.00
169_A	173_E	0.822	1.00
346_V	437_G	0.820	1.00
349_M	433_V	0.820	1.00
310_L	317_N	0.820	1.00
99_Q	103_H	0.819	1.00
494_A	497_A	0.818	1.00
350_H	353_A	0.815	1.00
277_A	280_R	0.813	1.00
131_Y	135_T	0.812	1.00
399_G	403_N	0.811	1.00
335_A	444_V	0.807	1.00
305_A	308_E	0.804	1.00
219_P	247_M	0.801	1.00
301_E	305_A	0.801	1.00
266_T	269_R	0.800	1.00
5_I	13_M	0.799	1.00
137_L	141_L	0.799	1.00
497_A	500_E	0.796	1.00
437_G	440_M	0.795	1.00
170_L	173_E	0.795	1.00
356_S	422_S	0.795	1.00
140_Y	144_G	0.794	1.00
479_D	483_Q	0.793	1.00
167_Q	170_L	0.793	1.00
500_E	504_S	0.793	1.00
286_N	489_V	0.793	1.00
55_S	58_D	0.791	1.00
97_L	101_A	0.791	1.00
330_S	334_T	0.791	1.00
150_F	154_T	0.789	1.00
367_D	413_K	0.788	1.00
96_T	99_Q	0.788	1.00
468_I	472_A	0.787	1.00
100_A	103_H	0.786	1.00
280_R	500_E	0.785	1.00
455_G	459_S	0.785	1.00
308_E	472_A	0.783	1.00
34_H	38_K	0.781	1.00
357_K	361_D	0.780	1.00
91_D	94_R	0.778	1.00
469_D	472_A	0.778	1.00
231_A	256_H	0.778	1.00
299_A	302_E	0.777	1.00
506_L	513_F	0.777	1.00
62_Q	66_N	0.773	1.00
160_A	164_A	0.773	1.00
182_D	186_D	0.771	1.00
25_S	29_F	0.770	1.00
40_F	44_N	0.767	1.00
265_V	268_V	0.767	1.00
279_T	496_A	0.764	1.00
42_V	46_L	0.764	1.00
226_H	254_V	0.764	1.00
361_D	365_V	0.763	1.00
142_D	146_T	0.761	1.00
136_E	153_P	0.760	1.00
103_H	106_K	0.758	1.00
95_K	99_Q	0.756	1.00
318_A	321_A	0.756	1.00
276_Y	507_T	0.755	1.00
123_I	127_Y	0.754	1.00
505_R	509_A	0.754	1.00
363_I	416_K	0.753	1.00
344_G	435_S	0.750	1.00
296_Q	310_L	0.750	1.00
30_F	191_Q	0.750	1.00
104_Y	107_F	0.749	1.00
175_L	179_I	0.747	1.00
234_N	514_R	0.746	1.00
320_N	324_A	0.745	1.00
232_G	260_S	0.745	1.00
216_L	219_P	0.744	1.00
343_D	441_N	0.742	1.00
243_G	247_M	0.741	1.00
263_D	266_T	0.741	1.00
103_H	107_F	0.740	1.00
254_V	257_M	0.740	1.00
345_V	433_V	0.736	1.00
38_K	41_V	0.734	1.00
18_F	22_Q	0.734	1.00
236_A	515_L	0.732	1.00
33_L	36_S	0.730	1.00
15_L	18_F	0.729	1.00
485_N	489_V	0.729	1.00
154_T	161_M	0.727	1.00
349_M	430_S	0.727	1.00
407_R	414_E	0.726	1.00
106_K	110_M	0.724	1.00
426_V	429_G	0.724	1.00
502_Q	505_R	0.724	1.00
76_M	79_S	0.723	1.00
452_D	456_E	0.722	1.00
324_A	328_A	0.720	1.00
37_Q	41_V	0.720	1.00
213_R	216_L	0.720	1.00
39_S	42_V	0.720	1.00
227_I	230_I	0.716	1.00
14_V	21_L	0.715	1.00
503_A	513_F	0.715	1.00
74_M	141_L	0.713	1.00
157_M	160_A	0.711	1.00
34_H	37_Q	0.711	1.00
31_S	34_H	0.709	1.00
423_V	427_D	0.709	1.00
499_L	503_A	0.708	1.00
363_I	367_D	0.707	1.00
28_L	31_S	0.705	1.00
150_F	153_P	0.703	1.00
73_R	77_D	0.699	1.00
40_F	183_N	0.699	1.00
312_A	315_K	0.699	1.00
161_M	165_F	0.698	1.00
167_Q	171_S	0.697	1.00
193_Q	197_I	0.695	1.00
306_S	310_L	0.695	1.00
486_A	489_V	0.694	1.00
19_A	209_W	0.693	1.00
168_Y	171_S	0.690	1.00
14_V	18_F	0.686	1.00
171_S	174_K	0.684	1.00
7_V	220_L	0.683	1.00
458_A	461_S	0.682	1.00
167_Q	174_K	0.682	1.00
300_L	303_T	0.679	1.00
181_T	184_A	0.678	1.00
140_Y	148_A	0.678	1.00
444_V	448_T	0.676	1.00
237_N	258_Q	0.673	1.00
436_A	439_T	0.673	1.00
44_N	47_R	0.671	1.00
144_G	147_G	0.668	1.00
304_A	307_M	0.667	1.00
52_E	55_S	0.667	1.00
421_D	424_S	0.666	1.00
361_D	414_E	0.665	1.00
36_S	40_F	0.665	1.00
342_V	346_V	0.665	1.00
281_E	491_E	0.663	1.00
112_P	115_E	0.661	1.00
429_G	433_V	0.661	1.00
362_I	419_I	0.658	1.00
241_I	248_G	0.656	1.00
151_A	154_T	0.655	1.00
327_L	330_S	0.652	1.00
93_A	97_L	0.652	1.00
71_A	75_M	0.648	1.00
75_M	78_S	0.648	1.00
425_R	428_T	0.647	1.00
156_G	161_M	0.647	1.00
371_F	409_A	0.645	1.00
117_V	120_S	0.643	1.00
487_S	494_A	0.642	1.00
32_S	190_A	0.640	1.00
314_V	317_N	0.640	1.00
296_Q	303_T	0.639	1.00
296_Q	307_M	0.638	1.00
492_S	495_A	0.636	1.00
126_K	164_A	0.635	1.00
9_T	12_V	0.634	1.00
346_V	350_H	0.634	1.00
303_T	307_M	0.633	1.00
274_A	277_A	0.633	1.00
142_D	145_N	0.632	1.00
271_G	274_A	0.631	1.00
310_L	314_V	0.630	1.00
296_Q	299_A	0.628	1.00
449_R	453_I	0.628	1.00
215_M	218_T	0.628	1.00
122_N	164_A	0.625	1.00
257_M	261_L	0.624	1.00
356_S	362_I	0.623	1.00
463_E	467_G	0.622	1.00
471_V	475_V	0.621	1.00
296_Q	306_S	0.620	1.00
420_E	423_V	0.619	1.00
334_T	446_A	0.618	1.00
231_A	253_S	0.617	1.00
183_N	187_Y	0.616	1.00
217_L	247_M	0.615	1.00
203_L	207_V	0.614	1.00
254_V	258_Q	0.613	1.00
362_I	411_A	0.613	1.00
42_V	45_Q	0.612	1.00
321_A	325_S	0.612	1.00
12_V	213_R	0.612	1.00
352_I	355_S	0.611	1.00
318_A	324_A	0.611	1.00
63_T	67_L	0.608	1.00
108_K	121_R	0.606	1.00
140_Y	143_Y	0.605	1.00
292_R	296_Q	0.605	1.00
175_L	178_D	0.604	1.00
289_L	293_T	0.604	1.00
378_L	386_R	0.602	1.00
348_T	425_R	0.601	1.00
68_S	71_A	0.601	1.00
230_I	261_L	0.601	1.00
119_T	127_Y	0.600	1.00
43_S	46_L	0.600	1.00
324_A	331_A	0.599	1.00
158_Q	162_G	0.599	1.00
461_S	464_Q	0.599	1.00
272_S	276_Y	0.598	1.00
337_H	442_N	0.597	1.00
184_A	187_Y	0.597	1.00
186_D	189_F	0.596	1.00
266_T	515_L	0.596	1.00
464_Q	471_V	0.594	1.00
258_Q	261_L	0.590	1.00
30_F	194_L	0.590	1.00
328_A	334_T	0.589	1.00
127_Y	131_Y	0.589	1.00
338_G	443_I	0.587	1.00
53_L	57_W	0.587	1.00
310_L	468_I	0.585	1.00
153_P	157_M	0.584	1.00
375_I	382_V	0.583	1.00
299_A	474_A	0.583	1.00
364_S	367_D	0.581	1.00
472_A	476_S	0.580	1.00
269_R	507_T	0.580	1.00
176_Y	179_I	0.579	1.00
275_I	499_L	0.578	1.00
339_G	345_V	0.577	1.00
264_T	267_H	0.577	1.00
226_H	230_I	0.576	1.00
22_Q	25_S	0.576	1.00
289_L	292_R	0.576	1.00
295_Q	477_E	0.575	1.00
359_I	419_I	0.574	1.00
205_L	209_W	0.573	1.00
23_L	26_G	0.572	1.00
374_N	402_R	0.567	1.00
119_T	124_D	0.567	1.00
307_M	475_V	0.566	1.00
336_Q	339_G	0.565	1.00
173_E	176_Y	0.564	1.00
101_A	131_Y	0.564	1.00
104_Y	108_K	0.562	1.00
405_A	408_S	0.561	1.00
37_Q	184_A	0.561	1.00
144_G	148_A	0.561	1.00
372_Q	400_E	0.560	1.00
269_R	511_S	0.560	1.00
275_I	502_Q	0.560	1.00
124_D	127_Y	0.560	1.00
268_V	506_L	0.560	1.00
362_I	365_V	0.560	1.00
66_N	70_S	0.559	1.00
299_A	306_S	0.556	1.00
108_K	112_P	0.556	1.00
126_K	130_Y	0.556	1.00
489_V	496_A	0.555	1.00
60_M	63_T	0.553	1.00
59_L	63_T	0.552	1.00
55_S	59_L	0.551	1.00
371_F	382_V	0.551	1.00
408_S	418_L	0.551	1.00
17_V	24_I	0.551	1.00
265_V	515_L	0.551	1.00
19_A	22_Q	0.550	1.00
207_V	210_Y	0.550	1.00
311_T	472_A	0.549	1.00
491_E	495_A	0.549	1.00
488_L	491_E	0.548	1.00
61_L	74_M	0.547	1.00
439_T	443_I	0.546	1.00
53_L	56_T	0.546	1.00
248_G	252_Q	0.545	1.00
311_T	314_V	0.544	1.00
7_V	216_L	0.543	1.00
447_V	454_M	0.543	1.00
38_K	42_V	0.541	1.00
223_I	226_H	0.539	1.00
182_D	185_D	0.538	1.00
186_D	190_A	0.538	1.00
144_G	149_Y	0.537	1.00
39_S	43_S	0.537	1.00
236_A	514_R	0.536	1.00
426_V	430_S	0.536	1.00
172_S	176_Y	0.535	1.00
310_L	324_A	0.533	1.00
228_R	231_A	0.531	1.00
8_V	221_A	0.531	1.00
163_E	166_A	0.530	1.00
43_S	47_R	0.530	1.00
344_G	348_T	0.530	1.00
166_A	169_A	0.528	1.00
133_A	137_L	0.528	1.00
352_I	426_V	0.527	1.00
120_S	123_I	0.526	1.00
327_L	449_R	0.526	1.00
86_K	93_A	0.525	1.00
112_P	116_M	0.523	1.00
302_E	470_Q	0.522	1.00
93_A	96_T	0.521	1.00
123_I	130_Y	0.521	1.00
134_L	137_L	0.520	1.00
300_L	478_M	0.518	1.00
51_G	54_T	0.517	1.00
9_T	13_M	0.516	1.00
69_R	72_V	0.516	1.00
301_E	479_D	0.516	1.00
233_G	264_T	0.516	1.00
200_V	204_I	0.514	1.00
288_D	484_Q	0.514	1.00
390_Q	401_V	0.513	1.00
329_Q	332_S	0.513	1.00
257_M	260_S	0.513	1.00
235_L	265_V	0.512	1.00
14_V	205_L	0.512	1.00
11_L	15_L	0.512	1.00
119_T	171_S	0.512	1.00
52_E	56_T	0.512	1.00
332_S	451_T	0.510	1.00
72_V	75_M	0.509	1.00
318_A	458_A	0.509	1.00
131_Y	134_L	0.508	1.00
377_A	402_R	0.507	1.00
33_L	37_Q	0.506	1.00
429_G	432_L	0.503	1.00
332_S	448_T	0.503	1.00
146_T	149_Y	0.501	1.00
334_T	439_T	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3zx6A	2	0.5479	100	0.355	Contact Map
1qu7A	2	0.4105	100	0.512	Contact Map
2ch7A	2	0.528	100	0.553	Contact Map
3g67A	2	0.3852	100	0.598	Contact Map
4i3mA	2	0.2658	99.9	0.745	Contact Map
4cq4A	4	0.1555	99.5	0.836	Contact Map
2f95B	2	0.0922	99.4	0.848	Contact Map
4gycB	2	0.1067	99.3	0.858	Contact Map
3zccA	2	0.1899	98.9	0.878	Contact Map
4i5sA	2	0.5732	98.4	0.896	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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