GREMLIN Database
POXB - Pyruvate dehydrogenase [ubiquinone]
UniProt: P07003 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG10754
Length: 572 (531)
Sequences: 14305 (9188)
Seq/√Len: 398.7

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
489_R492_E4.9171.00
365_Q508_D3.7691.00
459_N524_D3.5911.00
54_A84_G3.4231.00
499_I513_R3.4111.00
224_G244_N3.3691.00
218_E317_R3.2681.00
503_K506_E3.0761.00
19_K66_E3.0581.00
500_R526_V2.9521.00
192_R322_L2.8931.00
369_F512_Q2.8201.00
218_E313_K2.7541.00
63_L422_E2.6551.00
310_G315_T2.6101.00
499_I521_V2.5991.00
243_D394_N2.5481.00
497_T519_G2.5301.00
208_C219_L2.5081.00
365_Q368_H2.4901.00
20_R43_E2.4401.00
502_E506_E2.3911.00
14_E39_M2.3901.00
194_L289_I2.3551.00
499_I510_A2.3211.00
415_A429_A2.3041.00
72_G81_L2.2141.00
272_L312_I2.2081.00
486_N489_R2.1751.00
266_A269_L2.1621.00
500_R524_D2.1421.00
67_L149_V2.1301.00
7_A35_S2.1091.00
497_T513_R2.0821.00
331_F335_A2.0781.00
47_T53_A2.0591.00
368_H508_D2.0581.00
119_E122_R2.0491.00
271_L274_T2.0451.00
291_I315_T2.0451.00
422_E425_R2.0071.00
437_S494_C1.9791.00
490_I493_A1.9781.00
85_L97_A1.9761.00
197_L287_K1.9591.00
197_L306_M1.9401.00
206_L223_A1.9281.00
225_K320_L1.9231.00
96_L145_M1.9151.00
367_S392_K1.9061.00
197_L268_T1.9031.00
79_L83_N1.8981.00
488_A498_G1.8971.00
501_V510_A1.8961.00
99_A156_V1.8871.00
11_K15_S1.8651.00
198_L270_V1.8441.00
140_V157_V1.8431.00
188_E318_A1.8231.00
371_A374_A1.8221.00
339_Y343_R1.8031.00
7_A38_R1.7981.00
512_Q516_S1.7961.00
187_E190_E1.7831.00
436_F440_M1.7741.00
225_K324_E1.7661.00
67_L96_L1.7601.00
196_Q200_Y1.7521.00
508_D512_Q1.7511.00
223_A230_I1.7431.00
419_Q452_P1.7331.00
220_V224_G1.7171.00
221_E225_K1.7151.00
506_E509_E1.7121.00
457_V522_L1.7091.00
497_T521_V1.7071.00
206_L270_V1.7011.00
193_K196_Q1.6991.00
58_G62_Q1.6851.00
116_H119_E1.6611.00
514_A523_V1.6601.00
447_V496_I1.6551.00
502_E526_V1.6321.00
364_Q368_H1.6291.00
375_I418_A1.6251.00
206_L228_A1.5881.00
217_K221_E1.5811.00
361_Y504_A1.5611.00
369_F508_D1.5581.00
190_E193_K1.5501.00
133_S136_Q1.5491.00
410_N414_Q1.5491.00
11_K14_E1.5371.00
492_E497_T1.5321.00
379_D431_C1.5231.00
272_L291_I1.5221.00
125_S156_V1.5171.00
129_E157_V1.5131.00
474_G477_T1.5131.00
366_I430_M1.4991.00
64_S421_T1.4911.00
33_S44_W1.4881.00
509_E513_R1.4831.00
23_G44_W1.4801.00
227_K246_Y1.4791.00
488_A500_R1.4791.00
9_I159_L1.4761.00
379_D435_G1.4761.00
134_P166_K1.4711.00
198_L268_T1.4681.00
419_Q451_L1.4621.00
298_I309_V1.4621.00
400_L418_A1.4621.00
361_Y365_Q1.4531.00
201_S204_I1.4451.00
398_R425_R1.4301.00
126_H153_G1.4251.00
509_E512_Q1.4131.00
195_A322_L1.4121.00
12_T142_A1.4091.00
456_V523_V1.4001.00
268_T289_I1.3971.00
9_I141_L1.3951.00
365_Q369_F1.3871.00
230_I240_V1.3821.00
446_V496_I1.3731.00
52_V442_D1.3711.00
456_V511_L1.3681.00
98_I159_L1.3671.00
221_E320_L1.3661.00
14_E40_G1.3631.00
497_T517_I1.3591.00
446_V453_V1.3571.00
287_K305_D1.3541.00
374_A426_Q1.3541.00
362_L525_V1.3511.00
195_A319_L1.3461.00
16_A145_M1.3461.00
443_F496_I1.3461.00
104_S162_D1.3341.00
428_V515_F1.3331.00
372_D394_N1.3331.00
10_A39_M1.3301.00
67_L145_M1.3291.00
420_A451_L1.3281.00
20_R420_A1.3281.00
47_T56_A1.3231.00
456_V525_V1.3171.00
333_D337_E1.3141.00
43_E449_M1.3131.00
81_L97_A1.3031.00
335_A339_Y1.2981.00
440_M490_I1.2971.00
371_A426_Q1.2971.00
329_R333_D1.2941.00
201_S268_T1.2931.00
488_A492_E1.2911.00
272_L316_L1.2781.00
191_L322_L1.2781.00
370_A428_V1.2771.00
11_K39_M1.2741.00
517_I521_V1.2711.00
490_I494_C1.2641.00
85_L95_V1.2631.00
454_K514_A1.2601.00
429_A455_I1.2571.00
222_F226_I1.2561.00
96_L148_A1.2531.00
419_Q426_Q1.2491.00
54_A81_L1.2491.00
313_K317_R1.2451.00
205_A266_A1.2411.00
186_P315_T1.2401.00
192_R196_Q1.2381.00
16_A142_A1.2361.00
136_Q139_Q1.2361.00
461_S484_D1.2251.00
318_A321_P1.2241.00
426_Q515_F1.2241.00
222_F316_L1.2201.00
340_R344_K1.2191.00
311_D314_S1.2171.00
21_I36_L1.2171.00
452_P518_D1.2141.00
357_I525_V1.2131.00
78_N99_A1.2111.00
222_F320_L1.2111.00
131_V137_I1.2091.00
22_W60_E1.2051.00
452_P519_G1.1981.00
141_L157_V1.1961.00
416_L446_V1.1961.00
334_K338_D1.1891.00
219_L316_L1.1841.00
60_E421_T1.1841.00
6_A35_S1.1821.00
45_M420_A1.1801.00
489_R493_A1.1791.00
513_R517_I1.1771.00
507_V525_V1.1761.00
139_Q143_I1.1751.00
206_L222_F1.1721.00
299_G304_V1.1721.00
491_A522_L1.1711.00
357_I362_L1.1701.00
375_I427_V1.1691.00
193_K197_L1.1671.00
8_Y168_A1.1671.00
261_H265_N1.1651.00
12_T141_L1.1631.00
220_V241_E1.1611.00
4_T167_P1.1611.00
232_H247_D1.1581.00
18_V69_V1.1581.00
314_S317_R1.1551.00
372_D395_G1.1551.00
375_I422_E1.1491.00
208_C212_C1.1461.00
188_E322_L1.1431.00
61_A94_P1.1421.00
129_E140_V1.1421.00
476_L480_T1.1381.00
221_E224_G1.1381.00
491_A496_I1.1371.00
496_I522_L1.1351.00
510_A523_V1.1321.00
19_K43_E1.1291.00
199_R324_E1.1251.00
218_E221_E1.1191.00
160_P163_V1.1171.00
212_C219_L1.1171.00
129_E143_I1.1141.00
86_F405_H1.1121.00
220_V240_V1.1091.00
82_I120_L1.1091.00
491_A498_G1.1091.00
408_M438_M1.1081.00
477_T480_T1.1021.00
218_E320_L1.1011.00
58_G87_D1.0991.00
35_S38_R1.0971.00
58_G93_V1.0941.00
104_S166_K1.0921.00
5_V137_I1.0921.00
185_T318_A1.0911.00
63_L418_A1.0901.00
257_S261_H1.0851.00
248_V262_T1.0851.00
283_P286_A1.0841.00
337_E341_D1.0811.00
20_R45_M1.0811.00
131_V140_V1.0791.00
474_G478_D1.0791.00
203_N265_N1.0791.00
204_I267_D1.0751.00
9_I98_I1.0751.00
147_K155_S1.0741.00
82_I124_C1.0731.00
265_N334_K1.0721.00
376_F391_L1.0701.00
206_L219_L1.0671.00
199_R326_K1.0631.00
221_E317_R1.0631.00
474_G480_T1.0621.00
120_L124_C1.0601.00
4_T7_A1.0591.00
195_A199_R1.0571.00
105_S162_D1.0511.00
499_I523_V1.0511.00
217_K220_V1.0501.00
186_P318_A1.0481.00
444_L448_Q1.0461.00
337_E340_R1.0451.00
79_L120_L1.0431.00
224_G246_Y1.0431.00
507_V511_L1.0401.00
373_D425_R1.0401.00
426_Q454_K1.0391.00
231_V248_V1.0391.00
195_A323_V1.0381.00
54_A70_C1.0371.00
52_V439_L1.0351.00
461_S526_V1.0331.00
477_T481_E1.0311.00
336_L339_Y1.0311.00
304_V307_A1.0301.00
223_A240_V1.0301.00
498_G522_L1.0291.00
220_V244_N1.0281.00
59_A63_L1.0261.00
240_V244_N1.0261.00
89_H154_V1.0191.00
70_C81_L1.0191.00
454_K521_V1.0181.00
205_A231_V1.0161.00
107_I130_L1.0131.00
419_Q427_V1.0101.00
336_L340_R1.0101.00
314_S318_A1.0101.00
223_A246_Y1.0081.00
332_L336_L1.0061.00
513_R516_S1.0021.00
125_S128_C1.0021.00
370_A376_F1.0001.00
194_L308_L0.9951.00
412_M436_F0.9941.00
200_Y287_K0.9931.00
8_Y138_P0.9931.00
45_M449_M0.9921.00
501_V506_E0.9911.00
237_K242_Y0.9861.00
419_Q423_P0.9851.00
21_I69_V0.9841.00
127_Y147_K0.9791.00
436_F457_V0.9791.00
377_T427_V0.9771.00
194_L306_M0.9761.00
501_V507_V0.9731.00
29_L32_L0.9631.00
271_L276_F0.9631.00
185_T314_S0.9611.00
358_H531_E0.9551.00
7_A11_K0.9521.00
199_R323_V0.9451.00
85_L121_F0.9391.00
9_I32_L0.9391.00
411_A429_A0.9381.00
118_Q128_C0.9381.00
72_G97_A0.9381.00
367_S391_L0.9351.00
514_A521_V0.9321.00
419_Q424_E0.9311.00
225_K325_E0.9301.00
377_T429_A0.9301.00
128_C156_V0.9281.00
395_G398_R0.9251.00
457_V487_F0.9251.00
196_Q199_R0.9231.00
201_S267_D0.9221.00
32_L159_L0.9221.00
216_H220_V0.9221.00
363_A430_M0.9221.00
101_H158_V0.9181.00
444_L494_C0.9171.00
443_F522_L0.9161.00
70_C97_A0.9141.00
510_A514_A0.9141.00
66_E149_V0.9131.00
54_A95_V0.9081.00
127_Y140_V0.9061.00
369_F511_L0.9061.00
506_E510_A0.9041.00
118_Q130_L0.9041.00
467_A481_E0.9001.00
218_E316_L0.8991.00
440_M494_C0.8991.00
454_K515_F0.8981.00
200_Y268_T0.8981.00
488_A524_D0.8971.00
205_A263_M0.8961.00
78_N121_F0.8931.00
458_F527_V0.8921.00
143_I147_K0.8911.00
189_E192_R0.8901.00
387_A430_M0.8901.00
446_V455_I0.8881.00
62_Q93_V0.8871.00
443_F455_I0.8871.00
362_L458_F0.8821.00
282_Y286_A0.8821.00
496_I520_P0.8811.00
361_Y507_V0.8791.00
499_I517_I0.8771.00
478_D482_L0.8741.00
454_K523_V0.8741.00
194_L268_T0.8721.00
188_E192_R0.8701.00
12_T16_A0.8701.00
251_T263_M0.8691.00
436_F522_L0.8681.00
5_V134_P0.8661.00
36_L42_I0.8661.00
510_A513_R0.8651.00
59_A414_Q0.8641.00
119_E123_E0.8621.00
374_A428_V0.8601.00
473_G478_D0.8591.00
222_F323_V0.8571.00
191_L318_A0.8561.00
215_A218_E0.8541.00
205_A269_L0.8541.00
419_Q519_G0.8521.00
437_S440_M0.8501.00
450_K518_D0.8501.00
373_D395_G0.8461.00
79_L86_F0.8421.00
226_I323_V0.8381.00
242_Y247_D0.8381.00
344_K347_D0.8381.00
473_G480_T0.8371.00
338_D342_A0.8351.00
31_G165_L0.8341.00
34_D37_N0.8341.00
196_Q326_K0.8341.00
331_F334_K0.8331.00
148_A155_S0.8291.00
417_G421_T0.8291.00
63_L400_L0.8291.00
203_N267_D0.8281.00
194_L315_T0.8281.00
186_P191_L0.8271.00
221_E324_E0.8261.00
197_L289_I0.8261.00
340_R343_R0.8241.00
308_L315_T0.8241.00
430_M458_F0.8231.00
365_Q507_V0.8221.00
473_G476_L0.8201.00
369_F515_F0.8181.00
434_G463_L0.8171.00
82_I121_F0.8171.00
461_S529_K0.8151.00
159_L164_A0.8131.00
56_A446_V0.8131.00
12_T15_S0.8111.00
318_A322_L0.8101.00
20_R60_E0.8081.00
291_I308_L0.8061.00
446_V520_P0.8061.00
363_A458_F0.8051.00
69_V96_L0.8051.00
492_E498_G0.8041.00
83_N407_S0.8011.00
127_Y144_A0.8001.00
206_L272_L0.7991.00
428_V456_V0.7971.00
268_T287_K0.7941.00
453_V520_P0.7931.00
476_L479_G0.7921.00
295_P309_V0.7921.00
214_G397_R0.7911.00
486_N500_R0.7901.00
127_Y143_I0.7871.00
208_C232_H0.7841.00
4_T35_S0.7821.00
330_K333_D0.7821.00
55_F407_S0.7811.00
339_Y342_A0.7801.00
193_K306_M0.7781.00
341_D345_G0.7761.00
448_Q483_H0.7741.00
298_I307_A0.7701.00
194_L197_L0.7691.00
208_C230_I0.7691.00
475_Y478_D0.7661.00
13_L69_V0.7661.00
7_A39_M0.7631.00
363_A391_L0.7611.00
96_L149_V0.7611.00
63_L421_T0.7611.00
447_V520_P0.7591.00
486_N492_E0.7591.00
212_C239_H0.7581.00
19_K60_E0.7571.00
126_H147_K0.7561.00
357_I504_A0.7551.00
367_S394_N0.7551.00
459_N526_V0.7531.00
243_D372_D0.7511.00
474_G479_G0.7511.00
215_A313_K0.7481.00
473_G477_T0.7481.00
415_A453_V0.7481.00
416_L451_L0.7471.00
454_K518_D0.7471.00
333_D336_L0.7441.00
146_R150_L0.7441.00
332_L335_A0.7441.00
240_V247_D0.7421.00
126_H155_S0.7421.00
127_Y155_S0.7401.00
16_A149_V0.7401.00
481_E529_K0.7401.00
134_P138_P0.7371.00
18_V145_M0.7361.00
130_L158_V0.7351.00
25_T46_S0.7351.00
505_S509_E0.7331.00
335_A338_D0.7331.00
338_D341_D0.7311.00
14_E19_K0.7311.00
265_N338_D0.7301.00
473_G479_G0.7301.00
378_C387_A0.7261.00
86_F124_C0.7241.00
412_M455_I0.7231.00
467_A471_K0.7221.00
270_V291_I0.7211.00
21_I71_A0.7201.00
22_W56_A0.7201.00
71_A98_I0.7181.00
34_D476_L0.7151.00
375_I425_R0.7151.00
328_D331_F0.7141.00
61_A93_V0.7141.00
34_D38_R0.7141.00
232_H242_Y0.7131.00
317_R320_L0.7121.00
72_G99_A0.7111.00
190_E194_L0.7101.00
334_K337_E0.7091.00
92_H152_R0.7081.00
47_T52_V0.7081.00
475_Y480_T0.7081.00
317_R321_P0.7081.00
85_L124_C0.7081.00
134_P168_A0.7061.00
199_R322_L0.7051.00
378_C399_L0.7041.00
430_M456_V0.7021.00
210_S235_R0.7021.00
370_A374_A0.7011.00
118_Q122_R0.6991.00
199_R321_P0.6991.00
383_P435_G0.6931.00
335_A343_R0.6931.00
321_P324_E0.6931.00
447_V495_G0.6921.00
104_S132_S0.6921.00
190_E308_L0.6921.00
51_E80_H0.6891.00
29_L71_A0.6891.00
479_G482_L0.6881.00
462_V467_A0.6881.00
330_K334_K0.6871.00
99_A158_V0.6861.00
261_H264_M0.6861.00
474_G481_E0.6850.99
426_Q452_P0.6840.99
379_D411_A0.6830.99
204_I228_A0.6820.99
428_V454_K0.6820.99
143_I146_R0.6820.99
32_L164_A0.6800.99
455_I496_I0.6800.99
216_H396_K0.6790.99
185_T188_E0.6790.99
204_I268_T0.6780.99
140_V143_I0.6770.99
93_V410_N0.6750.99
241_E394_N0.6740.99
54_A97_A0.6740.99
331_F339_Y0.6740.99
357_I503_K0.6730.99
437_S485_T0.6720.99
447_V483_H0.6720.99
202_S267_D0.6720.99
446_V451_L0.6710.99
32_L71_A0.6700.99
378_C401_G0.6700.99
37_N476_L0.6700.99
234_L388_A0.6690.99
101_H107_I0.6690.99
362_L456_V0.6680.99
89_H126_H0.6680.99
498_G524_D0.6660.99
377_T418_A0.6660.99
60_E66_E0.6650.99
79_L82_I0.6650.99
456_V507_V0.6640.99
476_L481_E0.6640.99
197_L200_Y0.6630.99
471_K477_T0.6620.99
315_T318_A0.6610.99
134_P163_V0.6590.99
20_R66_E0.6580.99
15_S174_M0.6570.99
478_D481_E0.6570.99
206_L230_I0.6560.99
416_L445_S0.6560.99
241_E244_N0.6560.99
126_H151_N0.6560.99
496_I519_G0.6560.99
412_M442_D0.6560.99
320_L324_E0.6550.99
29_L33_S0.6540.99
207_M271_L0.6530.99
213_A311_D0.6500.99
252_G255_G0.6500.99
24_V81_L0.6490.99
436_F487_F0.6490.99
377_T400_L0.6490.99
429_A435_G0.6460.99
60_E64_S0.6450.99
61_A95_V0.6440.99
437_S487_F0.6420.99
73_S113_Q0.6420.99
186_P314_S0.6410.99
138_P142_A0.6390.99
415_A427_V0.6390.99
88_C95_V0.6370.99
207_M233_A0.6360.99
147_K151_N0.6360.99
227_K245_P0.6360.99
43_E423_P0.6350.99
79_L115_T0.6340.99
72_G78_N0.6330.99
341_D344_K0.6310.99
452_P520_P0.6310.99
226_I246_Y0.6300.99
144_A157_V0.6290.99
420_A449_M0.6250.99
121_F156_V0.6250.99
477_T482_L0.6250.99
48_R448_Q0.6230.99
198_L226_I0.6220.99
218_E222_F0.6210.99
31_G164_A0.6210.99
342_A345_G0.6200.99
342_A346_L0.6180.99
108_G114_E0.6170.99
29_L100_A0.6150.99
366_I456_V0.6130.99
136_Q140_V0.6130.99
5_V8_Y0.6120.99
315_T319_L0.6120.99
191_L308_L0.6100.99
290_Q304_V0.6090.99
322_L326_K0.6080.99
412_M431_C0.6070.99
510_A521_V0.6060.99
431_C455_I0.6050.99
518_D521_V0.6050.99
400_L410_N0.6040.99
260_F264_M0.6020.99
271_L288_I0.6020.99
80_H83_N0.6010.99
90_R405_H0.6000.99
511_L515_F0.6000.99
356_A528_A0.5990.99
485_T493_A0.5980.99
211_G292_D0.5980.99
412_M446_V0.5980.99
503_K509_E0.5970.99
377_T411_A0.5950.99
237_K393_M0.5920.99
21_I42_I0.5920.99
362_L507_V0.5920.99
219_L223_A0.5910.99
221_E321_P0.5900.99
223_A226_I0.5900.99
501_V523_V0.5900.99
345_G348_D0.5890.98
55_F87_D0.5890.98
145_M149_V0.5880.98
131_V160_P0.5860.98
225_K323_V0.5860.98
355_K503_K0.5850.98
19_K64_S0.5840.98
215_A312_I0.5830.98
104_S160_P0.5820.98
98_I141_L0.5820.98
86_F115_T0.5810.98
343_R347_D0.5810.98
378_C411_A0.5810.98
43_E420_A0.5810.98
207_M274_T0.5780.98
99_A117_P0.5780.98
413_P442_D0.5780.98
59_A417_G0.5760.98
339_Y344_K0.5750.98
499_I509_E0.5750.98
96_L155_S0.5720.98
418_A427_V0.5700.98
361_Y508_D0.5690.98
24_V463_L0.5680.98
297_S300_A0.5680.98
292_D297_S0.5670.98
213_A313_K0.5670.98
60_E68_A0.5660.98
431_C439_L0.5660.98
186_P310_G0.5650.98
191_L319_L0.5650.98
14_E42_I0.5650.98
56_A420_A0.5640.98
298_I304_V0.5630.98
436_F455_I0.5630.98
104_S133_S0.5620.98
162_D166_K0.5620.98
207_M269_L0.5600.98
363_A367_S0.5600.98
476_L482_L0.5590.98
232_H237_K0.5590.98
177_Y180_P0.5590.98
374_A425_R0.5590.98
238_E242_Y0.5580.98
370_A391_L0.5550.98
69_V145_M0.5550.98
12_T138_P0.5540.98
69_V98_I0.5530.98
450_K519_G0.5530.98
220_V223_A0.5520.98
312_I317_R0.5520.98
455_I522_L0.5510.98
235_R403_F0.5510.98
129_E155_S0.5500.98
49_H80_H0.5500.98
112_F406_G0.5470.98
190_E306_M0.5460.98
454_K519_G0.5450.98
147_K150_L0.5450.98
501_V509_E0.5450.98
101_H130_L0.5450.98
199_R202_S0.5440.97
183_V311_D0.5440.97
227_K325_E0.5430.97
67_L148_A0.5420.97
445_S451_L0.5410.97
104_S163_V0.5400.97
10_A36_L0.5390.97
96_L157_V0.5390.97
486_N524_D0.5390.97
485_T490_I0.5390.97
227_K332_L0.5390.97
44_W479_G0.5380.97
370_A515_F0.5380.97
22_W420_A0.5360.97
63_L375_I0.5350.97
395_G425_R0.5350.97
15_S170_E0.5340.97
360_Q531_E0.5320.97
350_A364_Q0.5310.97
12_T145_M0.5310.97
217_K224_G0.5310.97
440_M493_A0.5300.97
81_L99_A0.5300.97
347_D392_K0.5290.97
355_K504_A0.5280.97
58_G414_Q0.5280.97
61_A68_A0.5280.97
27_D73_S0.5270.97
45_M445_S0.5270.97
387_A399_L0.5260.97
5_V166_K0.5260.97
61_A67_L0.5260.97
375_I400_L0.5260.97
339_Y347_D0.5260.97
323_V326_K0.5250.97
353_S505_S0.5250.97
474_G482_L0.5250.97
383_P458_F0.5250.97
24_V47_T0.5240.97
98_I157_V0.5240.97
94_P148_A0.5240.97
203_N331_F0.5230.97
343_R392_K0.5230.97
62_Q91_N0.5220.97
294_N297_S0.5220.97
447_V450_K0.5220.97
473_G482_L0.5220.97
504_A508_D0.5220.97
138_P141_L0.5210.97
48_R444_L0.5210.97
17_G66_E0.5200.97
344_K348_D0.5190.97
242_Y392_K0.5190.97
393_M398_R0.5190.97
467_A529_K0.5190.97
146_R149_V0.5180.97
187_E314_S0.5180.97
53_A70_C0.5170.97
27_D469_E0.5160.97
89_H125_S0.5160.97
202_S330_K0.5150.97
205_A262_T0.5150.97
188_E321_P0.5150.97
444_L485_T0.5150.97
445_S449_M0.5150.97
289_I306_M0.5140.96
492_E499_I0.5130.96
54_A85_L0.5120.96
103_P106_E0.5120.96
122_R128_C0.5110.96
373_D426_Q0.5090.96
513_R521_V0.5080.96
437_S441_G0.5080.96
202_S328_D0.5080.96
37_N478_D0.5070.96
442_D445_S0.5060.96
486_N493_A0.5050.96
210_S275_Q0.5040.96
431_C435_G0.5020.96
126_H150_L0.5020.96
288_I302_S0.5000.96
137_I159_L0.5000.96
371_A515_F0.5000.96
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3eyaA 5 0.9231 100 0.171 Contact Map
1v5eA 4 0.993 100 0.19 Contact Map
1ozhA 4 0.9406 100 0.193 Contact Map
4kgdA 4 0.993 100 0.193 Contact Map
2pgnA 4 0.9685 100 0.201 Contact Map
1ybhA 4 0.958 100 0.201 Contact Map
1t9bA 2 0.9895 100 0.202 Contact Map
2ihtA 4 0.9301 100 0.206 Contact Map
4rjjA 5 0.9493 100 0.207 Contact Map
2panA 3 0.986 100 0.208 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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