POXB - ECOLI - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

POXB - Pyruvate dehydrogenase [ubiquinone]

UniProt:	P07003	Sequences: MKQTVAAYIAKTLESAGVKRIWGVTGDSLNGLSDSLNRMGTIEWMSTRHEEVAAFAAGAEAQLSGELAVCAGSCGPGNLHLINGLFDCHRNHVPVLAIAAHIPSSEIGSGYFQETHPQELFRECSHYCELVSSPEQIPQVLAIAMRKAVLNRGVSVVVLPGDVALKPAPEGATMHWYHAPQPVVTPEEEELRKLAQLLRYSSNIALMCGSGCAGAHKELVEFAGKIKAPIVHALRGKEHVEYDNPYDVGMTGLIGFSSGFHTMMNADTLVLLGTQFPYRAFYPTDAKIIQIDINPASIGAHSKVDMALVGDIKSTLRALLPLVEEKADRKFLDKALEDYRDARKGLDDLAKPSEKAIHPQYLAQQISHFAADDAIFTCDVGTPTVWAARYLKMNGKRRLLGSFNHGSMANAMPQALGAQATEPERQVVAMCGDGGFSMLMGDFLSVVQMKLPVKIVVFNNSVLGFVAMEMKAGGYLTDGTELHDTNFARIAEACGITGIRVEKASEVDEALQRAFSIDGPVLVDVVVAKEELAIPPQIKLEQAKGFSLYMLRAIISGRGDEVIELAKTNWLR	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10754
Length:	572 (531)
Sequences:	14305 (9188)
Seq/√Len:	398.7

ECOLI - POXB ILVB GCL ILVI ILVG OXC MEND
BACSU - YDAP ILVX IOLD ILVB MEND
HALSA - MEND
SULSO - Q97UP3 Q97ZB3 Q7LXT8 Q97V62 Q97U16 Q980V7 Q97XR3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
489_R	492_E	4.917	1.00
365_Q	508_D	3.769	1.00
459_N	524_D	3.591	1.00
54_A	84_G	3.423	1.00
499_I	513_R	3.411	1.00
224_G	244_N	3.369	1.00
218_E	317_R	3.268	1.00
503_K	506_E	3.076	1.00
19_K	66_E	3.058	1.00
500_R	526_V	2.952	1.00
192_R	322_L	2.893	1.00
369_F	512_Q	2.820	1.00
218_E	313_K	2.754	1.00
63_L	422_E	2.655	1.00
310_G	315_T	2.610	1.00
499_I	521_V	2.599	1.00
243_D	394_N	2.548	1.00
497_T	519_G	2.530	1.00
208_C	219_L	2.508	1.00
365_Q	368_H	2.490	1.00
20_R	43_E	2.440	1.00
502_E	506_E	2.391	1.00
14_E	39_M	2.390	1.00
194_L	289_I	2.355	1.00
499_I	510_A	2.321	1.00
415_A	429_A	2.304	1.00
72_G	81_L	2.214	1.00
272_L	312_I	2.208	1.00
486_N	489_R	2.175	1.00
266_A	269_L	2.162	1.00
500_R	524_D	2.142	1.00
67_L	149_V	2.130	1.00
7_A	35_S	2.109	1.00
497_T	513_R	2.082	1.00
331_F	335_A	2.078	1.00
47_T	53_A	2.059	1.00
368_H	508_D	2.058	1.00
119_E	122_R	2.049	1.00
271_L	274_T	2.045	1.00
291_I	315_T	2.045	1.00
422_E	425_R	2.007	1.00
437_S	494_C	1.979	1.00
490_I	493_A	1.978	1.00
85_L	97_A	1.976	1.00
197_L	287_K	1.959	1.00
197_L	306_M	1.940	1.00
206_L	223_A	1.928	1.00
225_K	320_L	1.923	1.00
96_L	145_M	1.915	1.00
367_S	392_K	1.906	1.00
197_L	268_T	1.903	1.00
79_L	83_N	1.898	1.00
488_A	498_G	1.897	1.00
501_V	510_A	1.896	1.00
99_A	156_V	1.887	1.00
11_K	15_S	1.865	1.00
198_L	270_V	1.844	1.00
140_V	157_V	1.843	1.00
188_E	318_A	1.823	1.00
371_A	374_A	1.822	1.00
339_Y	343_R	1.803	1.00
7_A	38_R	1.798	1.00
512_Q	516_S	1.796	1.00
187_E	190_E	1.783	1.00
436_F	440_M	1.774	1.00
225_K	324_E	1.766	1.00
67_L	96_L	1.760	1.00
196_Q	200_Y	1.752	1.00
508_D	512_Q	1.751	1.00
223_A	230_I	1.743	1.00
419_Q	452_P	1.733	1.00
220_V	224_G	1.717	1.00
221_E	225_K	1.715	1.00
506_E	509_E	1.712	1.00
457_V	522_L	1.709	1.00
497_T	521_V	1.707	1.00
206_L	270_V	1.701	1.00
193_K	196_Q	1.699	1.00
58_G	62_Q	1.685	1.00
116_H	119_E	1.661	1.00
514_A	523_V	1.660	1.00
447_V	496_I	1.655	1.00
502_E	526_V	1.632	1.00
364_Q	368_H	1.629	1.00
375_I	418_A	1.625	1.00
206_L	228_A	1.588	1.00
217_K	221_E	1.581	1.00
361_Y	504_A	1.561	1.00
369_F	508_D	1.558	1.00
190_E	193_K	1.550	1.00
133_S	136_Q	1.549	1.00
410_N	414_Q	1.549	1.00
11_K	14_E	1.537	1.00
492_E	497_T	1.532	1.00
379_D	431_C	1.523	1.00
272_L	291_I	1.522	1.00
125_S	156_V	1.517	1.00
129_E	157_V	1.513	1.00
474_G	477_T	1.513	1.00
366_I	430_M	1.499	1.00
64_S	421_T	1.491	1.00
33_S	44_W	1.488	1.00
509_E	513_R	1.483	1.00
23_G	44_W	1.480	1.00
227_K	246_Y	1.479	1.00
488_A	500_R	1.479	1.00
9_I	159_L	1.476	1.00
379_D	435_G	1.476	1.00
134_P	166_K	1.471	1.00
198_L	268_T	1.468	1.00
419_Q	451_L	1.462	1.00
298_I	309_V	1.462	1.00
400_L	418_A	1.462	1.00
361_Y	365_Q	1.453	1.00
201_S	204_I	1.445	1.00
398_R	425_R	1.430	1.00
126_H	153_G	1.425	1.00
509_E	512_Q	1.413	1.00
195_A	322_L	1.412	1.00
12_T	142_A	1.409	1.00
456_V	523_V	1.400	1.00
268_T	289_I	1.397	1.00
9_I	141_L	1.395	1.00
365_Q	369_F	1.387	1.00
230_I	240_V	1.382	1.00
446_V	496_I	1.373	1.00
52_V	442_D	1.371	1.00
456_V	511_L	1.368	1.00
98_I	159_L	1.367	1.00
221_E	320_L	1.366	1.00
14_E	40_G	1.363	1.00
497_T	517_I	1.359	1.00
446_V	453_V	1.357	1.00
287_K	305_D	1.354	1.00
374_A	426_Q	1.354	1.00
362_L	525_V	1.351	1.00
195_A	319_L	1.346	1.00
16_A	145_M	1.346	1.00
443_F	496_I	1.346	1.00
104_S	162_D	1.334	1.00
428_V	515_F	1.333	1.00
372_D	394_N	1.333	1.00
10_A	39_M	1.330	1.00
67_L	145_M	1.329	1.00
420_A	451_L	1.328	1.00
20_R	420_A	1.328	1.00
47_T	56_A	1.323	1.00
456_V	525_V	1.317	1.00
333_D	337_E	1.314	1.00
43_E	449_M	1.313	1.00
81_L	97_A	1.303	1.00
335_A	339_Y	1.298	1.00
440_M	490_I	1.297	1.00
371_A	426_Q	1.297	1.00
329_R	333_D	1.294	1.00
201_S	268_T	1.293	1.00
488_A	492_E	1.291	1.00
272_L	316_L	1.278	1.00
191_L	322_L	1.278	1.00
370_A	428_V	1.277	1.00
11_K	39_M	1.274	1.00
517_I	521_V	1.271	1.00
490_I	494_C	1.264	1.00
85_L	95_V	1.263	1.00
454_K	514_A	1.260	1.00
429_A	455_I	1.257	1.00
222_F	226_I	1.256	1.00
96_L	148_A	1.253	1.00
419_Q	426_Q	1.249	1.00
54_A	81_L	1.249	1.00
313_K	317_R	1.245	1.00
205_A	266_A	1.241	1.00
186_P	315_T	1.240	1.00
192_R	196_Q	1.238	1.00
16_A	142_A	1.236	1.00
136_Q	139_Q	1.236	1.00
461_S	484_D	1.225	1.00
318_A	321_P	1.224	1.00
426_Q	515_F	1.224	1.00
222_F	316_L	1.220	1.00
340_R	344_K	1.219	1.00
311_D	314_S	1.217	1.00
21_I	36_L	1.217	1.00
452_P	518_D	1.214	1.00
357_I	525_V	1.213	1.00
78_N	99_A	1.211	1.00
222_F	320_L	1.211	1.00
131_V	137_I	1.209	1.00
22_W	60_E	1.205	1.00
452_P	519_G	1.198	1.00
141_L	157_V	1.196	1.00
416_L	446_V	1.196	1.00
334_K	338_D	1.189	1.00
219_L	316_L	1.184	1.00
60_E	421_T	1.184	1.00
6_A	35_S	1.182	1.00
45_M	420_A	1.180	1.00
489_R	493_A	1.179	1.00
513_R	517_I	1.177	1.00
507_V	525_V	1.176	1.00
139_Q	143_I	1.175	1.00
206_L	222_F	1.172	1.00
299_G	304_V	1.172	1.00
491_A	522_L	1.171	1.00
357_I	362_L	1.170	1.00
375_I	427_V	1.169	1.00
193_K	197_L	1.167	1.00
8_Y	168_A	1.167	1.00
261_H	265_N	1.165	1.00
12_T	141_L	1.163	1.00
220_V	241_E	1.161	1.00
4_T	167_P	1.161	1.00
232_H	247_D	1.158	1.00
18_V	69_V	1.158	1.00
314_S	317_R	1.155	1.00
372_D	395_G	1.155	1.00
375_I	422_E	1.149	1.00
208_C	212_C	1.146	1.00
188_E	322_L	1.143	1.00
61_A	94_P	1.142	1.00
129_E	140_V	1.142	1.00
476_L	480_T	1.138	1.00
221_E	224_G	1.138	1.00
491_A	496_I	1.137	1.00
496_I	522_L	1.135	1.00
510_A	523_V	1.132	1.00
19_K	43_E	1.129	1.00
199_R	324_E	1.125	1.00
218_E	221_E	1.119	1.00
160_P	163_V	1.117	1.00
212_C	219_L	1.117	1.00
129_E	143_I	1.114	1.00
86_F	405_H	1.112	1.00
220_V	240_V	1.109	1.00
82_I	120_L	1.109	1.00
491_A	498_G	1.109	1.00
408_M	438_M	1.108	1.00
477_T	480_T	1.102	1.00
218_E	320_L	1.101	1.00
58_G	87_D	1.099	1.00
35_S	38_R	1.097	1.00
58_G	93_V	1.094	1.00
104_S	166_K	1.092	1.00
5_V	137_I	1.092	1.00
185_T	318_A	1.091	1.00
63_L	418_A	1.090	1.00
257_S	261_H	1.085	1.00
248_V	262_T	1.085	1.00
283_P	286_A	1.084	1.00
337_E	341_D	1.081	1.00
20_R	45_M	1.081	1.00
131_V	140_V	1.079	1.00
474_G	478_D	1.079	1.00
203_N	265_N	1.079	1.00
204_I	267_D	1.075	1.00
9_I	98_I	1.075	1.00
147_K	155_S	1.074	1.00
82_I	124_C	1.073	1.00
265_N	334_K	1.072	1.00
376_F	391_L	1.070	1.00
206_L	219_L	1.067	1.00
199_R	326_K	1.063	1.00
221_E	317_R	1.063	1.00
474_G	480_T	1.062	1.00
120_L	124_C	1.060	1.00
4_T	7_A	1.059	1.00
195_A	199_R	1.057	1.00
105_S	162_D	1.051	1.00
499_I	523_V	1.051	1.00
217_K	220_V	1.050	1.00
186_P	318_A	1.048	1.00
444_L	448_Q	1.046	1.00
337_E	340_R	1.045	1.00
79_L	120_L	1.043	1.00
224_G	246_Y	1.043	1.00
507_V	511_L	1.040	1.00
373_D	425_R	1.040	1.00
426_Q	454_K	1.039	1.00
231_V	248_V	1.039	1.00
195_A	323_V	1.038	1.00
54_A	70_C	1.037	1.00
52_V	439_L	1.035	1.00
461_S	526_V	1.033	1.00
477_T	481_E	1.031	1.00
336_L	339_Y	1.031	1.00
304_V	307_A	1.030	1.00
223_A	240_V	1.030	1.00
498_G	522_L	1.029	1.00
220_V	244_N	1.028	1.00
59_A	63_L	1.026	1.00
240_V	244_N	1.026	1.00
89_H	154_V	1.019	1.00
70_C	81_L	1.019	1.00
454_K	521_V	1.018	1.00
205_A	231_V	1.016	1.00
107_I	130_L	1.013	1.00
419_Q	427_V	1.010	1.00
336_L	340_R	1.010	1.00
314_S	318_A	1.010	1.00
223_A	246_Y	1.008	1.00
332_L	336_L	1.006	1.00
513_R	516_S	1.002	1.00
125_S	128_C	1.002	1.00
370_A	376_F	1.000	1.00
194_L	308_L	0.995	1.00
412_M	436_F	0.994	1.00
200_Y	287_K	0.993	1.00
8_Y	138_P	0.993	1.00
45_M	449_M	0.992	1.00
501_V	506_E	0.991	1.00
237_K	242_Y	0.986	1.00
419_Q	423_P	0.985	1.00
21_I	69_V	0.984	1.00
127_Y	147_K	0.979	1.00
436_F	457_V	0.979	1.00
377_T	427_V	0.977	1.00
194_L	306_M	0.976	1.00
501_V	507_V	0.973	1.00
29_L	32_L	0.963	1.00
271_L	276_F	0.963	1.00
185_T	314_S	0.961	1.00
358_H	531_E	0.955	1.00
7_A	11_K	0.952	1.00
199_R	323_V	0.945	1.00
85_L	121_F	0.939	1.00
9_I	32_L	0.939	1.00
411_A	429_A	0.938	1.00
118_Q	128_C	0.938	1.00
72_G	97_A	0.938	1.00
367_S	391_L	0.935	1.00
514_A	521_V	0.932	1.00
419_Q	424_E	0.931	1.00
225_K	325_E	0.930	1.00
377_T	429_A	0.930	1.00
128_C	156_V	0.928	1.00
395_G	398_R	0.925	1.00
457_V	487_F	0.925	1.00
196_Q	199_R	0.923	1.00
201_S	267_D	0.922	1.00
32_L	159_L	0.922	1.00
216_H	220_V	0.922	1.00
363_A	430_M	0.922	1.00
101_H	158_V	0.918	1.00
444_L	494_C	0.917	1.00
443_F	522_L	0.916	1.00
70_C	97_A	0.914	1.00
510_A	514_A	0.914	1.00
66_E	149_V	0.913	1.00
54_A	95_V	0.908	1.00
127_Y	140_V	0.906	1.00
369_F	511_L	0.906	1.00
506_E	510_A	0.904	1.00
118_Q	130_L	0.904	1.00
467_A	481_E	0.900	1.00
218_E	316_L	0.899	1.00
440_M	494_C	0.899	1.00
454_K	515_F	0.898	1.00
200_Y	268_T	0.898	1.00
488_A	524_D	0.897	1.00
205_A	263_M	0.896	1.00
78_N	121_F	0.893	1.00
458_F	527_V	0.892	1.00
143_I	147_K	0.891	1.00
189_E	192_R	0.890	1.00
387_A	430_M	0.890	1.00
446_V	455_I	0.888	1.00
62_Q	93_V	0.887	1.00
443_F	455_I	0.887	1.00
362_L	458_F	0.882	1.00
282_Y	286_A	0.882	1.00
496_I	520_P	0.881	1.00
361_Y	507_V	0.879	1.00
499_I	517_I	0.877	1.00
478_D	482_L	0.874	1.00
454_K	523_V	0.874	1.00
194_L	268_T	0.872	1.00
188_E	192_R	0.870	1.00
12_T	16_A	0.870	1.00
251_T	263_M	0.869	1.00
436_F	522_L	0.868	1.00
5_V	134_P	0.866	1.00
36_L	42_I	0.866	1.00
510_A	513_R	0.865	1.00
59_A	414_Q	0.864	1.00
119_E	123_E	0.862	1.00
374_A	428_V	0.860	1.00
473_G	478_D	0.859	1.00
222_F	323_V	0.857	1.00
191_L	318_A	0.856	1.00
215_A	218_E	0.854	1.00
205_A	269_L	0.854	1.00
419_Q	519_G	0.852	1.00
437_S	440_M	0.850	1.00
450_K	518_D	0.850	1.00
373_D	395_G	0.846	1.00
79_L	86_F	0.842	1.00
226_I	323_V	0.838	1.00
242_Y	247_D	0.838	1.00
344_K	347_D	0.838	1.00
473_G	480_T	0.837	1.00
338_D	342_A	0.835	1.00
31_G	165_L	0.834	1.00
34_D	37_N	0.834	1.00
196_Q	326_K	0.834	1.00
331_F	334_K	0.833	1.00
148_A	155_S	0.829	1.00
417_G	421_T	0.829	1.00
63_L	400_L	0.829	1.00
203_N	267_D	0.828	1.00
194_L	315_T	0.828	1.00
186_P	191_L	0.827	1.00
221_E	324_E	0.826	1.00
197_L	289_I	0.826	1.00
340_R	343_R	0.824	1.00
308_L	315_T	0.824	1.00
430_M	458_F	0.823	1.00
365_Q	507_V	0.822	1.00
473_G	476_L	0.820	1.00
369_F	515_F	0.818	1.00
434_G	463_L	0.817	1.00
82_I	121_F	0.817	1.00
461_S	529_K	0.815	1.00
159_L	164_A	0.813	1.00
56_A	446_V	0.813	1.00
12_T	15_S	0.811	1.00
318_A	322_L	0.810	1.00
20_R	60_E	0.808	1.00
291_I	308_L	0.806	1.00
446_V	520_P	0.806	1.00
363_A	458_F	0.805	1.00
69_V	96_L	0.805	1.00
492_E	498_G	0.804	1.00
83_N	407_S	0.801	1.00
127_Y	144_A	0.800	1.00
206_L	272_L	0.799	1.00
428_V	456_V	0.797	1.00
268_T	287_K	0.794	1.00
453_V	520_P	0.793	1.00
476_L	479_G	0.792	1.00
295_P	309_V	0.792	1.00
214_G	397_R	0.791	1.00
486_N	500_R	0.790	1.00
127_Y	143_I	0.787	1.00
208_C	232_H	0.784	1.00
4_T	35_S	0.782	1.00
330_K	333_D	0.782	1.00
55_F	407_S	0.781	1.00
339_Y	342_A	0.780	1.00
193_K	306_M	0.778	1.00
341_D	345_G	0.776	1.00
448_Q	483_H	0.774	1.00
298_I	307_A	0.770	1.00
194_L	197_L	0.769	1.00
208_C	230_I	0.769	1.00
475_Y	478_D	0.766	1.00
13_L	69_V	0.766	1.00
7_A	39_M	0.763	1.00
363_A	391_L	0.761	1.00
96_L	149_V	0.761	1.00
63_L	421_T	0.761	1.00
447_V	520_P	0.759	1.00
486_N	492_E	0.759	1.00
212_C	239_H	0.758	1.00
19_K	60_E	0.757	1.00
126_H	147_K	0.756	1.00
357_I	504_A	0.755	1.00
367_S	394_N	0.755	1.00
459_N	526_V	0.753	1.00
243_D	372_D	0.751	1.00
474_G	479_G	0.751	1.00
215_A	313_K	0.748	1.00
473_G	477_T	0.748	1.00
415_A	453_V	0.748	1.00
416_L	451_L	0.747	1.00
454_K	518_D	0.747	1.00
333_D	336_L	0.744	1.00
146_R	150_L	0.744	1.00
332_L	335_A	0.744	1.00
240_V	247_D	0.742	1.00
126_H	155_S	0.742	1.00
127_Y	155_S	0.740	1.00
16_A	149_V	0.740	1.00
481_E	529_K	0.740	1.00
134_P	138_P	0.737	1.00
18_V	145_M	0.736	1.00
130_L	158_V	0.735	1.00
25_T	46_S	0.735	1.00
505_S	509_E	0.733	1.00
335_A	338_D	0.733	1.00
338_D	341_D	0.731	1.00
14_E	19_K	0.731	1.00
265_N	338_D	0.730	1.00
473_G	479_G	0.730	1.00
378_C	387_A	0.726	1.00
86_F	124_C	0.724	1.00
412_M	455_I	0.723	1.00
467_A	471_K	0.722	1.00
270_V	291_I	0.721	1.00
21_I	71_A	0.720	1.00
22_W	56_A	0.720	1.00
71_A	98_I	0.718	1.00
34_D	476_L	0.715	1.00
375_I	425_R	0.715	1.00
328_D	331_F	0.714	1.00
61_A	93_V	0.714	1.00
34_D	38_R	0.714	1.00
232_H	242_Y	0.713	1.00
317_R	320_L	0.712	1.00
72_G	99_A	0.711	1.00
190_E	194_L	0.710	1.00
334_K	337_E	0.709	1.00
92_H	152_R	0.708	1.00
47_T	52_V	0.708	1.00
475_Y	480_T	0.708	1.00
317_R	321_P	0.708	1.00
85_L	124_C	0.708	1.00
134_P	168_A	0.706	1.00
199_R	322_L	0.705	1.00
378_C	399_L	0.704	1.00
430_M	456_V	0.702	1.00
210_S	235_R	0.702	1.00
370_A	374_A	0.701	1.00
118_Q	122_R	0.699	1.00
199_R	321_P	0.699	1.00
383_P	435_G	0.693	1.00
335_A	343_R	0.693	1.00
321_P	324_E	0.693	1.00
447_V	495_G	0.692	1.00
104_S	132_S	0.692	1.00
190_E	308_L	0.692	1.00
51_E	80_H	0.689	1.00
29_L	71_A	0.689	1.00
479_G	482_L	0.688	1.00
462_V	467_A	0.688	1.00
330_K	334_K	0.687	1.00
99_A	158_V	0.686	1.00
261_H	264_M	0.686	1.00
474_G	481_E	0.685	0.99
426_Q	452_P	0.684	0.99
379_D	411_A	0.683	0.99
204_I	228_A	0.682	0.99
428_V	454_K	0.682	0.99
143_I	146_R	0.682	0.99
32_L	164_A	0.680	0.99
455_I	496_I	0.680	0.99
216_H	396_K	0.679	0.99
185_T	188_E	0.679	0.99
204_I	268_T	0.678	0.99
140_V	143_I	0.677	0.99
93_V	410_N	0.675	0.99
241_E	394_N	0.674	0.99
54_A	97_A	0.674	0.99
331_F	339_Y	0.674	0.99
357_I	503_K	0.673	0.99
437_S	485_T	0.672	0.99
447_V	483_H	0.672	0.99
202_S	267_D	0.672	0.99
446_V	451_L	0.671	0.99
32_L	71_A	0.670	0.99
378_C	401_G	0.670	0.99
37_N	476_L	0.670	0.99
234_L	388_A	0.669	0.99
101_H	107_I	0.669	0.99
362_L	456_V	0.668	0.99
89_H	126_H	0.668	0.99
498_G	524_D	0.666	0.99
377_T	418_A	0.666	0.99
60_E	66_E	0.665	0.99
79_L	82_I	0.665	0.99
456_V	507_V	0.664	0.99
476_L	481_E	0.664	0.99
197_L	200_Y	0.663	0.99
471_K	477_T	0.662	0.99
315_T	318_A	0.661	0.99
134_P	163_V	0.659	0.99
20_R	66_E	0.658	0.99
15_S	174_M	0.657	0.99
478_D	481_E	0.657	0.99
206_L	230_I	0.656	0.99
416_L	445_S	0.656	0.99
241_E	244_N	0.656	0.99
126_H	151_N	0.656	0.99
496_I	519_G	0.656	0.99
412_M	442_D	0.656	0.99
320_L	324_E	0.655	0.99
29_L	33_S	0.654	0.99
207_M	271_L	0.653	0.99
213_A	311_D	0.650	0.99
252_G	255_G	0.650	0.99
24_V	81_L	0.649	0.99
436_F	487_F	0.649	0.99
377_T	400_L	0.649	0.99
429_A	435_G	0.646	0.99
60_E	64_S	0.645	0.99
61_A	95_V	0.644	0.99
437_S	487_F	0.642	0.99
73_S	113_Q	0.642	0.99
186_P	314_S	0.641	0.99
138_P	142_A	0.639	0.99
415_A	427_V	0.639	0.99
88_C	95_V	0.637	0.99
207_M	233_A	0.636	0.99
147_K	151_N	0.636	0.99
227_K	245_P	0.636	0.99
43_E	423_P	0.635	0.99
79_L	115_T	0.634	0.99
72_G	78_N	0.633	0.99
341_D	344_K	0.631	0.99
452_P	520_P	0.631	0.99
226_I	246_Y	0.630	0.99
144_A	157_V	0.629	0.99
420_A	449_M	0.625	0.99
121_F	156_V	0.625	0.99
477_T	482_L	0.625	0.99
48_R	448_Q	0.623	0.99
198_L	226_I	0.622	0.99
218_E	222_F	0.621	0.99
31_G	164_A	0.621	0.99
342_A	345_G	0.620	0.99
342_A	346_L	0.618	0.99
108_G	114_E	0.617	0.99
29_L	100_A	0.615	0.99
366_I	456_V	0.613	0.99
136_Q	140_V	0.613	0.99
5_V	8_Y	0.612	0.99
315_T	319_L	0.612	0.99
191_L	308_L	0.610	0.99
290_Q	304_V	0.609	0.99
322_L	326_K	0.608	0.99
412_M	431_C	0.607	0.99
510_A	521_V	0.606	0.99
431_C	455_I	0.605	0.99
518_D	521_V	0.605	0.99
400_L	410_N	0.604	0.99
260_F	264_M	0.602	0.99
271_L	288_I	0.602	0.99
80_H	83_N	0.601	0.99
90_R	405_H	0.600	0.99
511_L	515_F	0.600	0.99
356_A	528_A	0.599	0.99
485_T	493_A	0.598	0.99
211_G	292_D	0.598	0.99
412_M	446_V	0.598	0.99
503_K	509_E	0.597	0.99
377_T	411_A	0.595	0.99
237_K	393_M	0.592	0.99
21_I	42_I	0.592	0.99
362_L	507_V	0.592	0.99
219_L	223_A	0.591	0.99
221_E	321_P	0.590	0.99
223_A	226_I	0.590	0.99
501_V	523_V	0.590	0.99
345_G	348_D	0.589	0.98
55_F	87_D	0.589	0.98
145_M	149_V	0.588	0.98
131_V	160_P	0.586	0.98
225_K	323_V	0.586	0.98
355_K	503_K	0.585	0.98
19_K	64_S	0.584	0.98
215_A	312_I	0.583	0.98
104_S	160_P	0.582	0.98
98_I	141_L	0.582	0.98
86_F	115_T	0.581	0.98
343_R	347_D	0.581	0.98
378_C	411_A	0.581	0.98
43_E	420_A	0.581	0.98
207_M	274_T	0.578	0.98
99_A	117_P	0.578	0.98
413_P	442_D	0.578	0.98
59_A	417_G	0.576	0.98
339_Y	344_K	0.575	0.98
499_I	509_E	0.575	0.98
96_L	155_S	0.572	0.98
418_A	427_V	0.570	0.98
361_Y	508_D	0.569	0.98
24_V	463_L	0.568	0.98
297_S	300_A	0.568	0.98
292_D	297_S	0.567	0.98
213_A	313_K	0.567	0.98
60_E	68_A	0.566	0.98
431_C	439_L	0.566	0.98
186_P	310_G	0.565	0.98
191_L	319_L	0.565	0.98
14_E	42_I	0.565	0.98
56_A	420_A	0.564	0.98
298_I	304_V	0.563	0.98
436_F	455_I	0.563	0.98
104_S	133_S	0.562	0.98
162_D	166_K	0.562	0.98
207_M	269_L	0.560	0.98
363_A	367_S	0.560	0.98
476_L	482_L	0.559	0.98
232_H	237_K	0.559	0.98
177_Y	180_P	0.559	0.98
374_A	425_R	0.559	0.98
238_E	242_Y	0.558	0.98
370_A	391_L	0.555	0.98
69_V	145_M	0.555	0.98
12_T	138_P	0.554	0.98
69_V	98_I	0.553	0.98
450_K	519_G	0.553	0.98
220_V	223_A	0.552	0.98
312_I	317_R	0.552	0.98
455_I	522_L	0.551	0.98
235_R	403_F	0.551	0.98
129_E	155_S	0.550	0.98
49_H	80_H	0.550	0.98
112_F	406_G	0.547	0.98
190_E	306_M	0.546	0.98
454_K	519_G	0.545	0.98
147_K	150_L	0.545	0.98
501_V	509_E	0.545	0.98
101_H	130_L	0.545	0.98
199_R	202_S	0.544	0.97
183_V	311_D	0.544	0.97
227_K	325_E	0.543	0.97
67_L	148_A	0.542	0.97
445_S	451_L	0.541	0.97
104_S	163_V	0.540	0.97
10_A	36_L	0.539	0.97
96_L	157_V	0.539	0.97
486_N	524_D	0.539	0.97
485_T	490_I	0.539	0.97
227_K	332_L	0.539	0.97
44_W	479_G	0.538	0.97
370_A	515_F	0.538	0.97
22_W	420_A	0.536	0.97
63_L	375_I	0.535	0.97
395_G	425_R	0.535	0.97
15_S	170_E	0.534	0.97
360_Q	531_E	0.532	0.97
350_A	364_Q	0.531	0.97
12_T	145_M	0.531	0.97
217_K	224_G	0.531	0.97
440_M	493_A	0.530	0.97
81_L	99_A	0.530	0.97
347_D	392_K	0.529	0.97
355_K	504_A	0.528	0.97
58_G	414_Q	0.528	0.97
61_A	68_A	0.528	0.97
27_D	73_S	0.527	0.97
45_M	445_S	0.527	0.97
387_A	399_L	0.526	0.97
5_V	166_K	0.526	0.97
61_A	67_L	0.526	0.97
375_I	400_L	0.526	0.97
339_Y	347_D	0.526	0.97
323_V	326_K	0.525	0.97
353_S	505_S	0.525	0.97
474_G	482_L	0.525	0.97
383_P	458_F	0.525	0.97
24_V	47_T	0.524	0.97
98_I	157_V	0.524	0.97
94_P	148_A	0.524	0.97
203_N	331_F	0.523	0.97
343_R	392_K	0.523	0.97
62_Q	91_N	0.522	0.97
294_N	297_S	0.522	0.97
447_V	450_K	0.522	0.97
473_G	482_L	0.522	0.97
504_A	508_D	0.522	0.97
138_P	141_L	0.521	0.97
48_R	444_L	0.521	0.97
17_G	66_E	0.520	0.97
344_K	348_D	0.519	0.97
242_Y	392_K	0.519	0.97
393_M	398_R	0.519	0.97
467_A	529_K	0.519	0.97
146_R	149_V	0.518	0.97
187_E	314_S	0.518	0.97
53_A	70_C	0.517	0.97
27_D	469_E	0.516	0.97
89_H	125_S	0.516	0.97
202_S	330_K	0.515	0.97
205_A	262_T	0.515	0.97
188_E	321_P	0.515	0.97
444_L	485_T	0.515	0.97
445_S	449_M	0.515	0.97
289_I	306_M	0.514	0.96
492_E	499_I	0.513	0.96
54_A	85_L	0.512	0.96
103_P	106_E	0.512	0.96
122_R	128_C	0.511	0.96
373_D	426_Q	0.509	0.96
513_R	521_V	0.508	0.96
437_S	441_G	0.508	0.96
202_S	328_D	0.508	0.96
37_N	478_D	0.507	0.96
442_D	445_S	0.506	0.96
486_N	493_A	0.505	0.96
210_S	275_Q	0.504	0.96
431_C	435_G	0.502	0.96
126_H	150_L	0.502	0.96
288_I	302_S	0.500	0.96
137_I	159_L	0.500	0.96
371_A	515_F	0.500	0.96

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3eyaA	5	0.9231	100	0.171	Contact Map
1v5eA	4	0.993	100	0.19	Contact Map
1ozhA	4	0.9406	100	0.193	Contact Map
4kgdA	4	0.993	100	0.193	Contact Map
2pgnA	4	0.9685	100	0.201	Contact Map
1ybhA	4	0.958	100	0.201	Contact Map
1t9bA	2	0.9895	100	0.202	Contact Map
2ihtA	4	0.9301	100	0.206	Contact Map
4rjjA	5	0.9493	100	0.207	Contact Map
2panA	3	0.986	100	0.208	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0144 seconds.