PNTA - ECOLI - GREMLIN Contacts

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PNTA - NAD(P) transhydrogenase subunit alpha

UniProt:	P07001	Sequences: MRIGIPRERLTNETRVAATPKTVEQLLKLGFTVAVESGAGQLASFDDKAFVQAGAEIVEGNSVWQSEIILKVNAPLDDEIALLNPGTTLVSFIWPAQNPELMQKLAERNVTVMAMDSVPRISRAQSLDALSSMANIAGYRAIVEAAHEFGRFFTGQITAAGKVPPAKVMVIGAGVAGLAAIGAANSLGAIVRAFDTRPEVKEQVQSMGAEFLELDFKEEAGSGDGYAKVMSDAFIKAEMELFAAQAKEVDIIVTTALIPGKPAPKLITREMVDSMKAGSVIVDLAAQNGGNCEYTVPGEIFTTENGVKVIGYTDLPGRLPTQSSQLYGTNLVNLLKLLCKEKDGNITVDFDDVVIRGVTVIRAGEITWPAPPIQVSAQPQAAQKAAPEVKTEEKCTCSPWRKYALMALAIILFGWMASVAPKEFLGHFTVFALACVVGYYVVWNVSHALHTPLMSVTNAISGIIVVGALLQIGQGGWVSFLSFIAVLIASINIFGGFTVTQRMLKMFRKN	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10744
Length:	510 (508)
Sequences:	892 (453)
Seq/√Len:	20.1

ECOLI - PNTA

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
93_I	112_V	7.876	1.00
142_I	253_V	5.651	1.00
269_R	293_E	5.491	1.00
262_P	265_K	5.222	1.00
23_V	55_A	4.885	1.00
92_F	129_A	4.293	1.00
115_M	327_Y	4.269	1.00
235_I	238_E	4.146	1.00
296_V	299_E	4.030	1.00
294_Y	309_V	4.007	1.00
269_R	273_D	3.997	1.00
300_I	308_K	3.932	1.00
117_S	368_W	3.811	1.00
350_F	367_T	3.791	1.00
246_A	252_I	3.574	1.00
148_E	300_I	3.367	1.00
85_P	109_N	3.339	1.00
71_K	79_E	3.310	1.00
232_D	236_K	3.275	1.00
300_I	310_I	3.261	1.00
70_L	335_L	3.260	1.00
236_K	240_E	3.028	0.99
70_L	331_L	2.858	0.99
272_V	292_C	2.856	0.99
243_A	274_S	2.855	0.99
237_A	240_E	2.833	0.99
338_L	355_I	2.831	0.99
148_E	310_I	2.789	0.99
129_A	327_Y	2.786	0.99
48_K	51_V	2.772	0.99
235_I	239_M	2.766	0.99
296_V	301_F	2.695	0.98
212_L	241_L	2.691	0.98
245_Q	249_V	2.688	0.98
111_T	348_V	2.665	0.98
202_E	209_A	2.598	0.98
14_T	317_G	2.569	0.98
257_L	263_A	2.502	0.97
59_E	62_S	2.459	0.97
9_R	76_L	2.433	0.97
169_M	212_L	2.419	0.97
490_S	494_F	2.388	0.96
167_K	248_E	2.348	0.96
31_F	339_C	2.313	0.96
103_Q	106_A	2.223	0.95
37_S	57_I	2.220	0.95
235_I	242_F	2.201	0.94
99_P	103_Q	2.169	0.94
77_D	104_K	2.167	0.94
22_T	328_G	2.118	0.93
252_I	267_I	2.027	0.91
6_P	64_W	1.994	0.91
18_A	22_T	1.986	0.91
272_V	281_I	1.986	0.91
103_Q	107_E	1.957	0.90
167_K	249_V	1.934	0.89
63_V	69_I	1.928	0.89
48_K	52_Q	1.892	0.88
32_T	56_E	1.880	0.88
115_M	129_A	1.845	0.87
238_E	242_F	1.845	0.87
232_D	235_I	1.812	0.86
501_Q	505_K	1.796	0.86
73_N	287_Q	1.795	0.85
58_V	63_V	1.748	0.84
268_T	271_M	1.745	0.84
415_W	419_V	1.732	0.83
273_D	294_Y	1.726	0.83
5_I	18_A	1.724	0.83
167_K	245_Q	1.710	0.83
281_I	309_V	1.700	0.82
126_S	333_N	1.691	0.82
472_I	479_S	1.690	0.82
84_N	87_T	1.688	0.82
436_V	440_Y	1.686	0.82
13_E	73_N	1.684	0.82
243_A	271_M	1.655	0.80
192_R	245_Q	1.649	0.80
196_T	238_E	1.646	0.80
243_A	270_E	1.646	0.80
350_F	362_R	1.639	0.80
202_E	205_Q	1.630	0.79
8_E	13_E	1.628	0.79
121_I	124_A	1.618	0.79
271_M	274_S	1.616	0.79
273_D	305_N	1.609	0.78
230_M	238_E	1.604	0.78
362_R	365_E	1.596	0.78
464_I	489_A	1.590	0.78
182_G	207_M	1.586	0.77
281_I	292_C	1.571	0.77
6_P	209_A	1.566	0.76
427_H	464_I	1.560	0.76
427_H	430_V	1.551	0.76
300_I	312_Y	1.546	0.75
68_I	281_I	1.540	0.75
238_E	241_L	1.534	0.75
38_G	47_D	1.529	0.75
169_M	249_V	1.516	0.74
462_G	489_A	1.510	0.74
265_K	293_E	1.509	0.74
405_L	409_A	1.508	0.74
69_I	87_T	1.508	0.74
72_V	327_Y	1.497	0.73
212_L	249_V	1.497	0.73
201_K	213_E	1.493	0.73
179_A	183_A	1.491	0.73
439_Y	442_V	1.482	0.72
424_F	431_F	1.472	0.72
325_Q	328_G	1.465	0.71
239_M	242_F	1.457	0.71
205_Q	213_E	1.456	0.71
143_V	187_L	1.449	0.71
425_L	431_F	1.449	0.71
136_I	152_F	1.448	0.70
214_L	234_F	1.443	0.70
265_K	268_T	1.435	0.70
437_V	488_I	1.423	0.69
194_F	234_F	1.409	0.68
194_F	238_E	1.407	0.68
333_N	337_L	1.386	0.67
389_V	392_E	1.343	0.65
212_L	245_Q	1.337	0.64
148_E	308_K	1.335	0.64
192_R	249_V	1.328	0.64
63_V	66_S	1.312	0.63
126_S	337_L	1.310	0.63
2_R	66_S	1.304	0.62
292_C	309_V	1.293	0.61
216_F	229_V	1.292	0.61
257_L	288_N	1.287	0.61
500_T	504_L	1.281	0.61
61_N	69_I	1.279	0.61
249_V	252_I	1.262	0.60
267_I	271_M	1.260	0.59
61_N	82_L	1.260	0.59
245_Q	248_E	1.257	0.59
472_I	486_V	1.231	0.58
109_N	361_I	1.229	0.57
430_V	451_T	1.221	0.57
173_A	427_H	1.217	0.57
443_W	446_S	1.210	0.56
3_I	68_I	1.209	0.56
333_N	336_K	1.207	0.56
136_I	323_S	1.207	0.56
78_D	81_A	1.199	0.56
202_E	211_F	1.198	0.55
67_E	84_N	1.196	0.55
33_V	320_P	1.196	0.55
416_M	419_V	1.193	0.55
199_E	359_T	1.191	0.55
87_T	110_V	1.189	0.55
90_V	335_L	1.189	0.55
21_K	25_Q	1.186	0.55
424_F	428_F	1.184	0.55
157_I	182_G	1.178	0.54
122_S	170_V	1.177	0.54
169_M	238_E	1.174	0.54
51_V	56_E	1.172	0.54
96_A	114_A	1.172	0.54
20_P	45_F	1.167	0.53
230_M	241_L	1.167	0.53
194_F	242_F	1.165	0.53
416_M	432_A	1.163	0.53
118_V	127_L	1.163	0.53
192_R	248_E	1.161	0.53
235_I	241_L	1.151	0.52
234_F	239_M	1.145	0.52
127_L	358_V	1.144	0.52
126_S	440_Y	1.144	0.52
109_N	366_I	1.144	0.52
273_D	304_E	1.140	0.52
169_M	242_F	1.140	0.52
488_I	491_I	1.129	0.51
204_V	284_L	1.121	0.51
190_I	210_E	1.113	0.50
118_V	354_V	1.111	0.50
46_D	49_A	1.110	0.50
423_E	431_F	1.109	0.50
72_V	129_A	1.108	0.50
6_P	9_R	1.103	0.49
435_C	439_Y	1.096	0.49
241_L	245_Q	1.096	0.49
243_A	268_T	1.093	0.49
480_F	484_I	1.092	0.49
57_I	63_V	1.091	0.49
357_G	373_I	1.083	0.48
94_W	97_Q	1.082	0.48
232_D	240_E	1.079	0.48
196_T	239_M	1.075	0.48
110_V	361_I	1.074	0.47
417_A	425_L	1.073	0.47
212_L	238_E	1.066	0.47
194_F	235_I	1.065	0.47
269_R	305_N	1.064	0.47
10_L	73_N	1.064	0.47
233_A	493_I	1.061	0.47
404_A	408_L	1.059	0.46
22_T	325_Q	1.057	0.46
276_K	448_A	1.055	0.46
395_C	398_S	1.049	0.46
90_V	484_I	1.048	0.46
171_I	292_C	1.047	0.46
129_A	323_S	1.047	0.46
171_I	239_M	1.037	0.45
214_L	239_M	1.037	0.45
196_T	235_I	1.037	0.45
470_L	479_S	1.036	0.45
332_V	336_K	1.036	0.45
476_G	480_F	1.034	0.45
341_E	347_T	1.031	0.45
320_P	376_S	1.028	0.44
423_E	427_H	1.023	0.44
468_A	482_S	1.021	0.44
37_S	47_D	1.017	0.44
149_F	156_Q	1.016	0.44
169_M	235_I	1.015	0.44
207_M	434_A	1.012	0.43
230_M	235_I	1.011	0.43
106_A	366_I	1.009	0.43
85_P	108_R	1.008	0.43
246_A	266_L	1.007	0.43
83_L	110_V	1.004	0.43
152_F	163_V	1.001	0.43
104_K	107_E	1.000	0.43
263_A	288_N	0.999	0.43
7_R	36_E	0.997	0.43
485_A	489_A	0.996	0.42
150_G	154_T	0.992	0.42
126_S	332_V	0.984	0.42
135_N	326_L	0.984	0.42
143_V	310_I	0.979	0.41
15_R	152_F	0.977	0.41
118_V	334_L	0.970	0.41
113_M	359_T	0.970	0.41
194_F	239_M	0.967	0.41
462_G	488_I	0.963	0.40
91_S	114_A	0.957	0.40
97_Q	102_M	0.956	0.40
216_F	233_A	0.956	0.40
149_F	251_I	0.956	0.40
132_S	259_P	0.956	0.40
184_A	191_V	0.955	0.40
505_K	508_R	0.945	0.39
92_F	443_W	0.941	0.39
224_D	287_Q	0.936	0.39
81_A	108_R	0.934	0.39
194_F	216_F	0.934	0.39
31_F	346_I	0.930	0.38
205_Q	211_F	0.929	0.38
437_V	498_T	0.929	0.38
106_A	361_I	0.928	0.38
382_A	388_E	0.927	0.38
455_S	500_T	0.926	0.38
58_V	62_S	0.919	0.38
361_I	366_I	0.919	0.38
498_T	501_Q	0.917	0.38
163_V	179_A	0.915	0.37
427_H	442_V	0.914	0.37
464_I	471_Q	0.914	0.37
56_E	394_K	0.913	0.37
126_S	436_V	0.913	0.37
479_S	483_F	0.910	0.37
68_I	300_I	0.909	0.37
92_F	327_Y	0.905	0.37
443_W	456_V	0.903	0.37
209_A	213_E	0.900	0.36
5_I	488_I	0.898	0.36
312_Y	318_R	0.897	0.36
410_I	431_F	0.896	0.36
204_V	494_F	0.895	0.36
292_C	295_T	0.894	0.36
113_M	348_V	0.894	0.36
167_K	190_I	0.893	0.36
270_E	273_D	0.893	0.36
127_L	509_K	0.892	0.36
240_E	244_A	0.887	0.36
153_F	182_G	0.886	0.36
349_D	365_E	0.886	0.36
412_L	416_M	0.885	0.36
2_R	372_P	0.884	0.36
200_V	427_H	0.883	0.35
388_E	392_E	0.883	0.35
425_L	444_N	0.882	0.35
129_A	443_W	0.875	0.35
490_S	493_I	0.875	0.35
395_C	399_P	0.874	0.35
5_I	36_E	0.874	0.35
287_Q	317_G	0.874	0.35
431_F	434_A	0.872	0.35
478_V	481_L	0.872	0.35
41_Q	48_K	0.870	0.35
403_Y	464_I	0.867	0.35
112_V	361_I	0.865	0.34
481_L	488_I	0.864	0.34
57_I	501_Q	0.863	0.34
234_F	237_A	0.863	0.34
223_G	355_I	0.862	0.34
149_F	154_T	0.859	0.34
439_Y	443_W	0.856	0.34
356_R	371_P	0.848	0.33
447_H	466_V	0.846	0.33
432_A	436_V	0.846	0.33
231_S	234_F	0.844	0.33
146_A	153_F	0.841	0.33
332_V	337_L	0.841	0.33
140_R	144_E	0.840	0.33
13_E	79_E	0.839	0.33
97_Q	129_A	0.838	0.33
69_I	299_E	0.837	0.33
66_S	100_E	0.833	0.33
52_Q	384_K	0.829	0.32
121_I	354_V	0.829	0.32
14_T	42_L	0.828	0.32
34_A	58_V	0.827	0.32
219_E	490_S	0.826	0.32
259_P	266_L	0.825	0.32
33_V	319_L	0.825	0.32
55_A	320_P	0.824	0.32
194_F	233_A	0.824	0.32
413_F	425_L	0.824	0.32
320_P	436_V	0.824	0.32
69_I	108_R	0.824	0.32
502_R	506_M	0.824	0.32
243_A	247_K	0.819	0.32
88_T	111_T	0.818	0.32
462_G	490_S	0.817	0.32
55_A	87_T	0.816	0.32
389_V	394_K	0.815	0.32
57_I	478_V	0.815	0.32
69_I	111_T	0.814	0.31
482_S	486_V	0.812	0.31
65_Q	69_I	0.808	0.31
426_G	431_F	0.806	0.31
253_V	383_Q	0.801	0.31
15_R	234_F	0.801	0.31
224_D	337_L	0.798	0.31
136_I	331_L	0.797	0.31
382_A	386_A	0.797	0.31
200_V	368_W	0.794	0.30
58_V	434_A	0.788	0.30
455_S	504_L	0.787	0.30
474_Q	479_S	0.785	0.30
209_A	284_L	0.783	0.30
437_V	447_H	0.782	0.30
204_V	211_F	0.781	0.30
152_F	169_M	0.780	0.30
214_L	231_S	0.779	0.30
2_R	32_T	0.778	0.29
430_V	442_V	0.778	0.29
236_K	244_A	0.776	0.29
171_I	242_F	0.776	0.29
475_G	490_S	0.775	0.29
18_A	23_V	0.775	0.29
94_W	129_A	0.774	0.29
407_A	480_F	0.774	0.29
82_L	323_S	0.772	0.29
183_A	419_V	0.771	0.29
93_I	114_A	0.770	0.29
52_Q	385_A	0.770	0.29
111_T	268_T	0.766	0.29
66_S	116_D	0.764	0.29
223_G	229_V	0.764	0.29
241_L	249_V	0.763	0.29
212_L	235_I	0.762	0.29
112_V	431_F	0.762	0.29
71_K	80_I	0.760	0.29
488_I	498_T	0.760	0.29
473_G	479_S	0.759	0.28
137_A	434_A	0.758	0.28
333_N	436_V	0.756	0.28
482_S	490_S	0.754	0.28
171_I	194_F	0.753	0.28
173_A	486_V	0.752	0.28
366_I	477_W	0.751	0.28
401_R	404_A	0.751	0.28
8_E	15_R	0.749	0.28
137_A	257_L	0.748	0.28
337_L	451_T	0.747	0.28
64_W	111_T	0.747	0.28
199_E	339_C	0.746	0.28
96_A	200_V	0.746	0.28
49_A	52_Q	0.746	0.28
246_A	249_V	0.746	0.28
429_T	485_A	0.744	0.28
387_P	391_T	0.743	0.28
350_F	353_V	0.743	0.28
376_S	379_P	0.743	0.28
338_L	346_I	0.742	0.28
426_G	479_S	0.742	0.28
222_S	315_L	0.742	0.28
386_A	389_V	0.741	0.28
15_R	169_M	0.740	0.27
412_L	415_W	0.740	0.27
117_S	442_V	0.739	0.27
447_H	501_Q	0.739	0.27
43_A	304_E	0.738	0.27
131_S	135_N	0.737	0.27
33_V	55_A	0.736	0.27
198_P	221_G	0.733	0.27
117_S	204_V	0.731	0.27
51_V	58_V	0.730	0.27
224_D	373_I	0.728	0.27
431_F	444_N	0.728	0.27
413_F	417_A	0.726	0.27
273_D	293_E	0.726	0.27
424_F	444_N	0.726	0.27
401_R	416_M	0.725	0.27
428_F	441_V	0.725	0.27
140_R	179_A	0.724	0.27
414_G	417_A	0.723	0.27
63_V	319_L	0.723	0.27
243_A	265_K	0.722	0.27
140_R	300_I	0.721	0.27
337_L	354_V	0.721	0.27
66_S	405_L	0.720	0.26
271_M	431_F	0.718	0.26
171_I	241_L	0.718	0.26
339_C	346_I	0.715	0.26
451_T	464_I	0.712	0.26
273_D	297_P	0.711	0.26
463_I	491_I	0.711	0.26
376_S	494_F	0.711	0.26
171_I	298_G	0.709	0.26
444_N	464_I	0.708	0.26
441_V	464_I	0.708	0.26
357_G	368_W	0.708	0.26
171_I	235_I	0.707	0.26
81_A	477_W	0.707	0.26
341_E	345_N	0.707	0.26
207_M	455_S	0.706	0.26
66_S	281_I	0.703	0.26
231_S	237_A	0.701	0.26
171_I	196_T	0.698	0.25
465_V	489_A	0.698	0.25
45_F	350_F	0.697	0.25
92_F	323_S	0.696	0.25
104_K	108_R	0.696	0.25
183_A	228_K	0.696	0.25
270_E	293_E	0.695	0.25
427_H	437_V	0.694	0.25
36_E	85_P	0.693	0.25
230_M	234_F	0.692	0.25
296_V	304_E	0.692	0.25
297_P	301_F	0.692	0.25
94_W	112_V	0.691	0.25
167_K	192_R	0.689	0.25
476_G	479_S	0.688	0.25
3_I	8_E	0.687	0.25
431_F	509_K	0.686	0.25
89_L	252_I	0.686	0.25
59_E	82_L	0.685	0.25
3_I	276_K	0.685	0.25
356_R	369_P	0.685	0.25
4_G	8_E	0.684	0.25
179_A	372_P	0.683	0.25
6_P	79_E	0.682	0.25
404_A	477_W	0.679	0.24
13_E	72_V	0.679	0.24
383_Q	390_K	0.675	0.24
37_S	51_V	0.675	0.24
474_Q	483_F	0.675	0.24
15_R	92_F	0.675	0.24
15_R	212_L	0.675	0.24
234_F	242_F	0.674	0.24
194_F	284_L	0.674	0.24
90_V	137_A	0.674	0.24
281_I	294_Y	0.673	0.24
4_G	314_D	0.673	0.24
196_T	443_W	0.671	0.24
77_D	80_I	0.671	0.24
92_F	424_F	0.670	0.24
191_V	241_L	0.670	0.24
59_E	66_S	0.669	0.24
5_I	270_E	0.668	0.24
21_K	90_V	0.668	0.24
56_E	385_A	0.668	0.24
23_V	442_V	0.668	0.24
21_K	24_E	0.667	0.24
115_M	118_V	0.666	0.24
173_A	464_I	0.666	0.24
229_V	232_D	0.664	0.24
421_P	463_I	0.664	0.24
409_A	426_G	0.664	0.24
124_A	502_R	0.662	0.24
403_Y	465_V	0.662	0.24
414_G	488_I	0.661	0.24
472_I	487_L	0.661	0.24
137_A	401_R	0.661	0.24
219_E	229_V	0.659	0.23
370_A	442_V	0.658	0.23
15_R	134_A	0.656	0.23
406_M	416_M	0.655	0.23
102_M	365_E	0.654	0.23
423_E	444_N	0.654	0.23
60_G	401_R	0.653	0.23
224_D	440_Y	0.652	0.23
96_A	102_M	0.651	0.23
348_V	355_I	0.650	0.23
397_C	401_R	0.649	0.23
24_E	57_I	0.648	0.23
116_D	328_G	0.648	0.23
136_I	154_T	0.647	0.23
69_I	398_S	0.646	0.23
334_L	509_K	0.645	0.23
362_R	465_V	0.644	0.23
465_V	471_Q	0.644	0.23
127_L	451_T	0.644	0.23
482_S	494_F	0.642	0.23
234_F	292_C	0.642	0.23
92_F	292_C	0.642	0.23
410_I	464_I	0.640	0.23
440_Y	498_T	0.640	0.23
220_A	417_A	0.639	0.23
207_M	300_I	0.638	0.23
183_A	329_T	0.638	0.23
301_F	304_E	0.637	0.22
73_N	224_D	0.637	0.22
113_M	334_L	0.636	0.22
68_I	78_D	0.636	0.22
218_E	233_A	0.635	0.22
207_M	211_F	0.635	0.22
402_K	437_V	0.633	0.22
2_R	14_T	0.633	0.22
154_T	251_I	0.632	0.22
169_M	252_I	0.630	0.22
437_V	443_W	0.630	0.22
468_A	483_F	0.629	0.22
102_M	355_I	0.628	0.22
431_F	479_S	0.628	0.22
132_S	266_L	0.627	0.22
240_E	366_I	0.626	0.22
298_G	314_D	0.626	0.22
15_R	20_P	0.626	0.22
469_L	480_F	0.626	0.22
451_T	463_I	0.625	0.22
414_G	424_F	0.624	0.22
199_E	343_D	0.623	0.22
469_L	472_I	0.623	0.22
77_D	240_E	0.622	0.22
152_F	249_V	0.621	0.22
187_L	509_K	0.621	0.22
232_D	509_K	0.620	0.22
435_C	471_Q	0.619	0.22
444_N	451_T	0.619	0.22
31_F	94_W	0.619	0.22
58_V	321_T	0.617	0.22
68_I	335_L	0.616	0.22
69_I	83_L	0.616	0.22
6_P	240_E	0.615	0.21
196_T	229_V	0.615	0.21
93_I	105_L	0.614	0.21
294_Y	489_A	0.611	0.21
305_N	309_V	0.610	0.21
425_L	479_S	0.610	0.21
230_M	258_I	0.610	0.21
98_N	276_K	0.609	0.21
57_I	82_L	0.609	0.21
149_F	318_R	0.608	0.21
18_A	33_V	0.608	0.21
219_E	482_S	0.608	0.21
70_L	179_A	0.607	0.21
29_L	336_K	0.607	0.21
21_K	374_Q	0.606	0.21
287_Q	358_V	0.606	0.21
214_L	218_E	0.606	0.21
92_F	115_M	0.605	0.21
25_Q	448_A	0.605	0.21
196_T	237_A	0.604	0.21
281_I	354_V	0.604	0.21
375_V	466_V	0.604	0.21
28_K	115_M	0.604	0.21
349_D	355_I	0.602	0.21
396_T	399_P	0.602	0.21
437_V	446_S	0.602	0.21
130_L	134_A	0.601	0.21
8_E	17_A	0.600	0.21
494_F	508_R	0.599	0.21
423_E	442_V	0.599	0.21
247_K	271_M	0.598	0.21
137_A	198_P	0.597	0.21
304_E	468_A	0.597	0.21
463_I	470_L	0.596	0.21
228_K	491_I	0.596	0.21
72_V	92_F	0.595	0.21
340_K	344_G	0.595	0.21
464_I	499_V	0.595	0.21
90_V	253_V	0.594	0.21
94_W	288_N	0.594	0.21
58_V	181_I	0.592	0.21
7_R	262_P	0.592	0.21
111_T	323_S	0.591	0.20
234_F	248_E	0.591	0.20
309_V	441_V	0.591	0.20
191_V	282_V	0.590	0.20
277_A	428_F	0.589	0.20
196_T	242_F	0.588	0.20
71_K	101_L	0.587	0.20
475_G	483_F	0.586	0.20
477_W	485_A	0.586	0.20
48_K	493_I	0.584	0.20
265_K	297_P	0.584	0.20
395_C	448_A	0.584	0.20
149_F	163_V	0.584	0.20
409_A	479_S	0.583	0.20
273_D	296_V	0.583	0.20
224_D	333_N	0.582	0.20
27_L	484_I	0.579	0.20
122_S	323_S	0.579	0.20
284_L	435_C	0.578	0.20
5_I	409_A	0.578	0.20
79_E	428_F	0.578	0.20
444_N	484_I	0.577	0.20
425_L	464_I	0.577	0.20
420_A	473_G	0.575	0.20
150_G	162_K	0.575	0.20
199_E	468_A	0.574	0.20
403_Y	482_S	0.574	0.20
2_R	214_L	0.574	0.20
448_A	509_K	0.574	0.20
15_R	248_E	0.574	0.20
384_K	387_P	0.572	0.20
407_A	411_I	0.572	0.20
17_A	384_K	0.571	0.20
15_R	323_S	0.571	0.20
27_L	55_A	0.571	0.20
45_F	320_P	0.570	0.20
73_N	333_N	0.570	0.20
451_T	471_Q	0.570	0.20
437_V	474_Q	0.568	0.20
372_P	377_A	0.568	0.20
65_Q	78_D	0.568	0.20
89_L	112_V	0.568	0.20
232_D	333_N	0.567	0.19
385_A	389_V	0.567	0.19
300_I	439_Y	0.566	0.19
212_L	252_I	0.565	0.19
3_I	153_F	0.563	0.19
420_A	435_C	0.563	0.19
80_I	101_L	0.562	0.19
475_G	505_K	0.562	0.19
333_N	440_Y	0.562	0.19
167_K	232_D	0.562	0.19
249_V	268_T	0.561	0.19
396_T	442_V	0.560	0.19
52_Q	323_S	0.560	0.19
118_V	136_I	0.559	0.19
429_T	439_Y	0.558	0.19
272_V	309_V	0.557	0.19
210_E	230_M	0.555	0.19
440_Y	490_S	0.553	0.19
146_A	154_T	0.552	0.19
266_L	322_Q	0.551	0.19
201_K	222_S	0.551	0.19
423_E	509_K	0.551	0.19
470_L	478_V	0.551	0.19
234_F	238_E	0.550	0.19
462_G	487_L	0.550	0.19
404_A	475_G	0.550	0.19
224_D	375_V	0.549	0.19
18_A	87_T	0.549	0.19
353_V	374_Q	0.549	0.19
56_E	401_R	0.548	0.19
424_F	443_W	0.547	0.19
73_N	417_A	0.547	0.19
104_K	387_P	0.547	0.19
114_A	338_L	0.547	0.19
233_A	333_N	0.546	0.19
34_A	56_E	0.546	0.19
7_R	72_V	0.544	0.19
157_I	322_Q	0.544	0.19
415_W	493_I	0.543	0.19
192_R	210_E	0.543	0.19
196_T	212_L	0.543	0.19
130_L	285_A	0.540	0.18
196_T	455_S	0.539	0.18
70_L	357_G	0.539	0.18
173_A	441_V	0.539	0.18
202_E	488_I	0.538	0.18
245_Q	252_I	0.538	0.18
325_Q	329_T	0.537	0.18
428_F	509_K	0.536	0.18
478_V	498_T	0.535	0.18
483_F	490_S	0.535	0.18
22_T	332_V	0.535	0.18
196_T	252_I	0.534	0.18
198_P	274_S	0.533	0.18
395_C	403_Y	0.531	0.18
427_H	444_N	0.531	0.18
96_A	100_E	0.531	0.18
420_A	428_F	0.531	0.18
68_I	317_G	0.530	0.18
241_L	298_G	0.528	0.18
421_P	436_V	0.527	0.18
2_R	509_K	0.526	0.18
152_F	234_F	0.526	0.18
21_K	204_V	0.525	0.18
149_F	192_R	0.525	0.18
133_M	136_I	0.524	0.18
463_I	478_V	0.524	0.18
143_V	193_A	0.523	0.18
417_A	431_F	0.523	0.18
477_W	480_F	0.523	0.18
165_P	360_V	0.523	0.18
2_R	224_D	0.522	0.18
14_T	447_H	0.522	0.18
21_K	53_A	0.522	0.18
157_I	239_M	0.522	0.18
423_E	465_V	0.521	0.18
179_A	314_D	0.520	0.18
37_S	59_E	0.520	0.18
88_T	147_H	0.520	0.18
36_E	170_V	0.519	0.18
10_L	442_V	0.518	0.18
406_M	429_T	0.518	0.18
55_A	442_V	0.517	0.18
86_G	434_A	0.517	0.18
52_Q	386_A	0.517	0.18
436_V	463_I	0.516	0.17
34_A	66_S	0.516	0.17
16_V	50_F	0.516	0.17
36_E	418_S	0.515	0.17
97_Q	101_L	0.515	0.17
192_R	212_L	0.515	0.17
7_R	229_V	0.514	0.17
102_M	231_S	0.514	0.17
72_V	317_G	0.514	0.17
124_A	206_S	0.514	0.17
393_E	396_T	0.514	0.17
171_I	294_Y	0.513	0.17
70_L	413_F	0.512	0.17
133_M	360_V	0.512	0.17
374_Q	491_I	0.512	0.17
111_T	116_D	0.511	0.17
435_C	451_T	0.511	0.17
428_F	431_F	0.510	0.17
36_E	103_Q	0.510	0.17
21_K	151_R	0.509	0.17
191_V	212_L	0.508	0.17
381_A	475_G	0.508	0.17
419_V	472_I	0.507	0.17
126_S	319_L	0.506	0.17
194_F	213_E	0.506	0.17
218_E	231_S	0.506	0.17
113_M	157_I	0.506	0.17
234_F	258_I	0.506	0.17
66_S	87_T	0.506	0.17
455_S	502_R	0.505	0.17
14_T	287_Q	0.505	0.17
68_I	366_I	0.505	0.17
427_H	505_K	0.504	0.17
246_A	271_M	0.504	0.17
65_Q	71_K	0.504	0.17
309_V	489_A	0.504	0.17
43_A	58_V	0.503	0.17
287_Q	417_A	0.503	0.17
126_S	224_D	0.503	0.17
122_S	344_G	0.501	0.17
390_K	408_L	0.501	0.17
423_E	479_S	0.501	0.17
320_P	373_I	0.501	0.17
437_V	480_F	0.500	0.17

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2qrjA	1	0.6118	100	0.605	Contact Map
1x13A	2	0.7255	100	0.618	Contact Map
3p2yA	2	0.6706	100	0.686	Contact Map
4dioA	2	0.6843	100	0.711	Contact Map
1l7dA	2	0.6922	100	0.738	Contact Map
4izhA	2	0.7137	100	0.761	Contact Map
2eezA	5	0.6647	100	0.779	Contact Map
1pjcA	5	0.6922	100	0.795	Contact Map
4lmpA	5	0.7098	100	0.803	Contact Map
4o93A	2	0.1784	100	0.818	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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