MALT - ECOLI - GREMLIN Contacts

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MALT - HTH-type transcriptional regulator MalT

UniProt:	P06993	Sequences: MLIPSKLSRPVRLDHTVVRERLLAKLSGANNFRLALITSPAGYGKTTLISQWAAGKNDIGWYSLDEGDNQQERFASYLIAAVQQATNGHCAICETMAQKRQYASLTSLFAQLFIELAEWHSPLYLVIDDYHLITNPVIHESMRFFIRHQPENLTLVVLSRNLPQLGIANLRVRDQLLEIGSQQLAFTHQEAKQFFDCRLSSPIEAAESSRICDDVSGWATALQLIALSARQNTHSAHKSARRLAGINASHLSDYLVDEVLDNVDLATRHFLLKSAILRSMNDALITRVTGEENGQMRLEEIERQGLFLQRMDDTGEWFCYHPLFGNFLRQRCQWELAAELPEIHRAAAESWMAQGFPSEAIHHALAAGDALMLRDILLNHAWSLFNHSELSLLEESLKALPWDSLLENPQLVLLQAWLMQSQHRYGEVNTLLARAEHEIKDIREDTMHAEFNALRAQVAINDGNPDEAERLAKLALEELPPGWFYSRIVATSVLGEVLHCKGELTRSLALMQQTEQMARQHDVWHYALWSLIQQSEILFAQGFLQTAWETQEKAFQLINEQHLEQLPMHEFLVRIRAQLLWAWARLDEAEASARSGIEVLSSYQPQQQLQCLAMLIQCSLARGDLDNARSQLNRLENLLGNGKYHSDWISNANKVRVIYWQMTGDKAAAANWLRHTAKPEFANNHFLQGQWRNIARAQILLGEFEPAEIVLEELNENARSLRLMSDLNRNLLLLNQLYWQAGRKSDAQRVLLDALKLANRTGFISHFVIEGEAMAQQLRQLIQLNTLPELEQHRAQRILREINQHHRHKFAHFDENFVERLLNHPEVPELIRTSPLTQREWQVLGLIYSGYSNEQIAGELEVAATTIKTHIRNLYQKLGVAHRQDAVQHAQQLLKMMGYGV	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10562
Length:	901 (745)
Sequences:	8136 (7387)
Seq/√Len:	270.6

ECOLI - MALT

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
624_D	627_N	6.870	1.00
585_R	588_E	6.760	1.00
665_D	668_A	6.714	1.00
464_N	467_E	5.896	1.00
543_F	546_T	5.579	1.00
703_E	706_P	5.504	1.00
503_E	506_R	5.369	1.00
49_I	158_L	4.639	1.00
424_R	427_E	4.595	1.00
191_A	222_L	4.410	1.00
27_S	55_G	4.083	1.00
344_H	363_H	3.719	1.00
264_D	300_E	3.555	1.00
590_E	622_R	3.351	1.00
130_Y	157_V	3.303	1.00
187_T	190_E	3.136	1.00
743_R	746_D	3.055	1.00
277_L	347_A	2.895	1.00
657_V	673_L	2.837	1.00
26_L	52_W	2.690	1.00
594_R	615_L	2.658	1.00
267_T	300_E	2.643	1.00
552_E	576_R	2.628	1.00
47_T	51_Q	2.603	1.00
188_H	209_S	2.580	1.00
53_A	126_V	2.556	1.00
519_R	527_A	2.549	1.00
548_W	552_E	2.521	1.00
580_L	592_S	2.514	1.00
636_E	656_R	2.511	1.00
128_D	158_L	2.507	1.00
535_S	551_Q	2.497	1.00
590_E	594_R	2.492	1.00
629_R	663_T	2.478	1.00
577_A	593_A	2.459	1.00
389_E	392_L	2.439	1.00
61_W	66_E	2.425	1.00
495_G	511_M	2.420	1.00
267_T	301_I	2.363	1.00
274_S	320_Y	2.332	1.00
660_W	672_W	2.314	1.00
548_W	583_W	2.302	1.00
195_F	226_A	2.278	1.00
580_L	585_R	2.260	1.00
660_W	668_A	2.228	1.00
345_R	349_E	2.210	1.00
619_S	631_Q	2.188	1.00
660_W	665_D	2.186	1.00
538_L	550_T	2.177	1.00
272_L	339_E	2.167	1.00
211_I	222_L	2.137	1.00
580_L	588_E	2.112	1.00
456_A	472_A	2.069	1.00
252_S	330_Q	2.062	1.00
108_L	113_F	2.061	1.00
316_E	320_Y	2.058	1.00
39_S	43_Y	2.047	1.00
37_I	49_I	2.008	1.00
191_A	212_C	2.005	1.00
732_L	736_Q	1.963	1.00
619_S	627_N	1.955	1.00
49_I	126_V	1.941	1.00
531_L	550_T	1.933	1.00
192_K	208_S	1.931	1.00
653_N	672_W	1.930	1.00
381_A	397_L	1.927	1.00
348_A	364_A	1.920	1.00
799_L	803_N	1.916	1.00
20_E	190_E	1.911	1.00
633_N	656_R	1.905	1.00
619_S	624_D	1.874	1.00
559_N	569_H	1.873	1.00
276_I	329_R	1.866	1.00
508_L	512_Q	1.860	1.00
519_R	553_K	1.859	1.00
508_L	541_Q	1.858	1.00
708_E	712_E	1.846	1.00
576_R	592_S	1.844	1.00
467_E	470_R	1.827	1.00
415_Q	419_M	1.825	1.00
23_L	51_Q	1.799	1.00
16_T	47_T	1.795	1.00
597_I	615_L	1.787	1.00
352_M	372_M	1.774	1.00
264_D	267_T	1.756	1.00
491_T	510_L	1.721	1.00
627_N	631_Q	1.720	1.00
275_A	329_R	1.709	1.00
715_N	734_L	1.708	1.00
775_A	782_I	1.705	1.00
429_N	433_A	1.704	1.00
51_Q	54_A	1.698	1.00
573_V	592_S	1.681	1.00
210_R	214_D	1.680	1.00
629_R	633_N	1.674	1.00
798_I	802_I	1.670	1.00
730_N	734_L	1.668	1.00
193_Q	197_C	1.657	1.00
329_R	340_L	1.651	1.00
452_N	471_L	1.640	1.00
190_E	193_Q	1.639	1.00
618_C	622_R	1.629	1.00
268_R	272_L	1.626	1.00
243_L	246_I	1.626	1.00
276_I	347_A	1.621	1.00
587_D	622_R	1.618	1.00
325_G	329_R	1.612	1.00
105_L	109_F	1.608	1.00
473_K	494_L	1.592	1.00
795_A	803_N	1.588	1.00
224_L	258_E	1.583	1.00
408_N	412_V	1.578	1.00
433_A	455_R	1.567	1.00
369_D	372_M	1.558	1.00
159_S	163_P	1.556	1.00
556_Q	560_E	1.553	1.00
38_T	178_E	1.551	1.00
656_R	672_W	1.547	1.00
24_A	28_G	1.539	1.00
596_G	611_C	1.532	1.00
52_W	156_V	1.525	1.00
612_L	634_R	1.523	1.00
798_I	805_H	1.520	1.00
612_L	631_Q	1.519	1.00
615_L	619_S	1.514	1.00
538_L	546_T	1.513	1.00
375_D	379_N	1.510	1.00
559_N	595_S	1.508	1.00
625_L	663_T	1.508	1.00
281_N	284_L	1.507	1.00
188_H	212_C	1.502	1.00
37_I	181_S	1.502	1.00
795_A	798_I	1.499	1.00
802_I	805_H	1.497	1.00
51_Q	55_G	1.495	1.00
629_R	660_W	1.489	1.00
534_Q	550_T	1.482	1.00
235_S	240_A	1.475	1.00
706_P	709_I	1.471	1.00
62_Y	66_E	1.464	1.00
767_F	771_G	1.464	1.00
670_A	701_L	1.462	1.00
135_N	138_I	1.462	1.00
26_L	35_A	1.461	1.00
209_S	213_D	1.456	1.00
41_A	160_R	1.454	1.00
798_I	803_N	1.453	1.00
795_A	804_Q	1.447	1.00
631_Q	634_R	1.441	1.00
144_F	148_H	1.439	1.00
50_S	63_S	1.438	1.00
798_I	801_E	1.432	1.00
25_K	177_L	1.429	1.00
279_S	317_W	1.425	1.00
512_Q	534_Q	1.417	1.00
751_L	754_A	1.416	1.00
242_R	245_G	1.413	1.00
742_G	747_A	1.410	1.00
256_V	331_R	1.410	1.00
753_D	757_L	1.407	1.00
419_M	431_L	1.407	1.00
535_S	547_A	1.398	1.00
588_E	592_S	1.397	1.00
653_N	675_H	1.397	1.00
43_Y	219_A	1.394	1.00
616_I	632_L	1.392	1.00
487_R	491_T	1.391	1.00
538_L	543_F	1.387	1.00
619_S	622_R	1.387	1.00
698_Q	706_P	1.381	1.00
356_F	359_E	1.376	1.00
483_W	486_S	1.375	1.00
362_H	366_A	1.375	1.00
419_M	427_E	1.374	1.00
590_E	619_S	1.374	1.00
634_R	637_N	1.367	1.00
573_V	595_S	1.359	1.00
271_L	301_I	1.355	1.00
626_D	663_T	1.352	1.00
548_W	580_L	1.351	1.00
765_S	769_I	1.351	1.00
712_E	734_L	1.350	1.00
550_T	553_K	1.349	1.00
105_L	108_L	1.348	1.00
270_F	289_T	1.347	1.00
36_L	157_V	1.344	1.00
265_L	268_R	1.337	1.00
627_N	630_S	1.336	1.00
340_L	344_H	1.326	1.00
491_T	513_Q	1.325	1.00
81_A	85_A	1.321	1.00
711_L	715_N	1.321	1.00
274_S	280_M	1.320	1.00
269_H	339_E	1.319	1.00
590_E	618_C	1.318	1.00
671_N	675_H	1.308	1.00
308_L	319_C	1.298	1.00
149_Q	153_L	1.298	1.00
774_M	778_L	1.297	1.00
562_H	566_L	1.297	1.00
494_L	510_L	1.294	1.00
326_N	330_Q	1.293	1.00
371_L	375_D	1.293	1.00
188_H	192_K	1.291	1.00
416_A	432_L	1.291	1.00
795_A	802_I	1.290	1.00
590_E	615_L	1.288	1.00
74_F	77_Y	1.287	1.00
17_V	197_C	1.287	1.00
579_L	583_W	1.286	1.00
36_L	159_S	1.284	1.00
553_K	556_Q	1.283	1.00
732_L	735_N	1.281	1.00
670_A	674_R	1.278	1.00
734_L	738_Y	1.277	1.00
469_E	473_K	1.275	1.00
284_L	350_S	1.270	1.00
306_L	324_F	1.269	1.00
576_R	580_L	1.268	1.00
555_F	559_N	1.267	1.00
224_L	227_L	1.266	1.00
104_S	116_L	1.266	1.00
629_R	656_R	1.265	1.00
280_M	318_F	1.265	1.00
61_W	65_D	1.264	1.00
668_A	671_N	1.259	1.00
615_L	631_Q	1.258	1.00
694_I	698_Q	1.258	1.00
765_S	768_V	1.257	1.00
593_A	614_M	1.256	1.00
674_R	678_K	1.253	1.00
73_R	76_S	1.247	1.00
329_R	344_H	1.246	1.00
415_Q	431_L	1.240	1.00
702_G	707_A	1.239	1.00
74_F	81_A	1.239	1.00
125_L	155_L	1.238	1.00
799_L	802_I	1.237	1.00
288_V	347_A	1.233	1.00
272_L	332_C	1.226	1.00
342_E	346_A	1.225	1.00
753_D	756_K	1.222	1.00
412_V	434_R	1.220	1.00
794_R	797_R	1.219	1.00
459_A	467_E	1.219	1.00
555_F	573_V	1.217	1.00
61_W	64_L	1.217	1.00
743_R	747_A	1.216	1.00
21_R	24_A	1.207	1.00
234_H	239_S	1.206	1.00
656_R	660_W	1.205	1.00
24_A	27_S	1.205	1.00
270_F	297_R	1.204	1.00
704_F	708_E	1.194	1.00
432_L	454_L	1.192	1.00
38_T	180_G	1.192	1.00
588_E	591_A	1.191	1.00
795_A	799_L	1.189	1.00
748_Q	752_L	1.187	1.00
333_Q	337_A	1.182	1.00
685_H	688_Q	1.179	1.00
498_L	510_L	1.179	1.00
672_W	675_H	1.178	1.00
23_L	52_W	1.177	1.00
75_A	78_L	1.177	1.00
436_E	455_R	1.176	1.00
397_L	400_L	1.175	1.00
77_Y	81_A	1.169	1.00
141_S	145_F	1.165	1.00
552_E	556_Q	1.164	1.00
668_A	672_W	1.159	1.00
204_E	207_E	1.156	1.00
747_A	754_A	1.156	1.00
360_A	364_A	1.151	1.00
546_T	549_E	1.150	1.00
801_E	804_Q	1.147	1.00
555_F	572_L	1.147	1.00
77_Y	80_A	1.143	1.00
506_R	509_A	1.139	1.00
548_W	585_R	1.138	1.00
775_A	779_R	1.137	1.00
273_K	347_A	1.136	1.00
75_A	85_A	1.134	1.00
358_S	383_S	1.134	1.00
549_E	553_K	1.133	1.00
531_L	553_K	1.132	1.00
620_L	625_L	1.131	1.00
429_N	455_R	1.130	1.00
480_P	487_R	1.130	1.00
398_K	427_E	1.126	1.00
661_Q	669_A	1.125	1.00
345_R	369_D	1.124	1.00
697_A	701_L	1.118	1.00
632_L	655_V	1.116	1.00
459_A	464_N	1.115	1.00
192_K	205_A	1.114	1.00
59_I	65_D	1.113	1.00
288_V	350_S	1.113	1.00
586_L	618_C	1.113	1.00
466_D	470_R	1.112	1.00
746_D	749_R	1.107	1.00
238_K	241_R	1.104	1.00
398_K	415_Q	1.104	1.00
27_S	52_W	1.104	1.00
801_E	805_H	1.103	1.00
660_W	663_T	1.101	1.00
404_S	407_E	1.100	1.00
34_L	146_I	1.099	1.00
385_F	418_L	1.099	1.00
797_R	801_E	1.099	1.00
130_Y	133_I	1.098	1.00
22_L	48_L	1.098	1.00
558_I	562_H	1.097	1.00
416_A	435_A	1.096	1.00
586_L	590_E	1.086	1.00
364_A	372_M	1.086	1.00
412_V	431_L	1.084	1.00
601_S	608_Q	1.084	1.00
215_V	222_L	1.083	1.00
475_A	479_L	1.082	1.00
494_L	498_L	1.077	1.00
106_T	110_A	1.072	1.00
21_R	25_K	1.072	1.00
750_V	753_D	1.069	1.00
45_K	160_R	1.068	1.00
491_T	517_M	1.068	1.00
754_A	758_A	1.066	1.00
128_D	131_H	1.065	1.00
15_H	197_C	1.065	1.00
448_H	452_N	1.065	1.00
59_I	62_Y	1.064	1.00
322_P	326_N	1.063	1.00
435_A	438_E	1.062	1.00
474_L	477_E	1.059	1.00
394_E	398_K	1.057	1.00
595_S	598_E	1.057	1.00
515_E	519_R	1.056	1.00
53_A	124_Y	1.054	1.00
586_L	622_R	1.053	1.00
523_V	526_Y	1.051	1.00
382_W	414_L	1.050	1.00
299_E	303_R	1.050	1.00
107_S	111_Q	1.049	1.00
210_R	213_D	1.048	1.00
630_S	634_R	1.047	1.00
449_A	475_A	1.046	1.00
277_L	280_M	1.046	1.00
535_S	554_A	1.043	1.00
534_Q	538_L	1.043	1.00
448_H	478_E	1.040	1.00
266_A	297_R	1.039	1.00
718_A	722_R	1.035	1.00
339_E	342_E	1.035	1.00
719_R	727_L	1.032	1.00
49_I	53_A	1.032	1.00
40_P	43_Y	1.032	1.00
508_L	538_L	1.032	1.00
774_M	777_Q	1.029	1.00
666_K	697_A	1.026	1.00
419_M	424_R	1.022	1.00
580_L	583_W	1.022	1.00
234_H	238_K	1.019	1.00
636_E	640_G	1.018	1.00
280_M	285_I	1.018	1.00
482_G	487_R	1.018	1.00
266_A	293_N	1.015	1.00
79_I	85_A	1.013	1.00
615_L	618_C	1.013	1.00
385_F	414_L	1.012	1.00
597_I	601_S	1.011	1.00
633_N	636_E	1.011	1.00
738_Y	743_R	1.011	1.00
37_I	158_L	1.010	1.00
528_L	531_L	1.008	1.00
313_D	316_E	1.005	1.00
696_R	699_I	1.005	1.00
38_T	159_S	1.005	1.00
452_N	474_L	1.005	1.00
429_N	462_D	1.004	1.00
78_L	141_S	1.000	1.00
692_R	695_A	1.000	1.00
749_R	753_D	0.998	1.00
256_V	261_D	0.995	1.00
287_R	353_A	0.993	1.00
758_A	761_T	0.990	1.00
473_K	477_E	0.989	1.00
220_T	321_H	0.989	1.00
747_A	751_L	0.989	1.00
372_M	375_D	0.988	1.00
378_L	410_Q	0.986	1.00
487_R	513_Q	0.986	1.00
276_I	343_I	0.984	1.00
470_R	474_L	0.980	1.00
49_I	156_V	0.979	1.00
771_G	801_E	0.977	1.00
632_L	656_R	0.976	1.00
47_T	223_Q	0.974	1.00
59_I	64_L	0.974	1.00
524_W	560_E	0.973	1.00
434_R	437_H	0.971	1.00
675_H	678_K	0.968	1.00
459_A	471_L	0.966	1.00
215_V	225_I	0.965	1.00
795_A	801_E	0.964	1.00
186_F	190_E	0.963	1.00
361_I	364_A	0.962	1.00
546_T	550_T	0.961	1.00
455_R	459_A	0.960	1.00
718_A	721_L	0.957	1.00
74_F	83_Q	0.956	1.00
261_D	268_R	0.956	1.00
62_Y	65_D	0.956	1.00
515_E	531_L	0.955	1.00
29_A	35_A	0.954	1.00
59_I	124_Y	0.954	1.00
16_T	51_Q	0.951	1.00
518_A	526_Y	0.948	1.00
772_E	775_A	0.947	1.00
632_L	636_E	0.947	1.00
333_Q	339_E	0.947	1.00
755_L	758_A	0.946	1.00
512_Q	516_Q	0.946	1.00
66_E	77_Y	0.944	1.00
364_A	376_I	0.943	1.00
191_A	226_A	0.942	1.00
559_N	562_H	0.940	1.00
659_Y	663_T	0.940	1.00
573_V	599_V	0.938	1.00
43_Y	218_W	0.937	1.00
766_H	769_I	0.936	1.00
64_L	69_N	0.934	1.00
506_R	510_L	0.933	1.00
667_A	701_L	0.933	1.00
795_A	805_H	0.932	1.00
191_A	215_V	0.931	1.00
537_I	541_Q	0.929	1.00
111_Q	114_I	0.929	1.00
734_L	737_L	0.927	1.00
363_H	366_A	0.926	1.00
126_V	158_L	0.926	1.00
759_N	762_G	0.922	1.00
775_A	781_L	0.922	1.00
389_E	393_L	0.921	1.00
744_K	747_A	0.921	1.00
752_L	756_K	0.921	1.00
670_A	698_Q	0.921	1.00
698_Q	703_E	0.920	1.00
593_A	615_L	0.919	1.00
256_V	327_F	0.919	1.00
731_L	750_V	0.919	1.00
634_R	638_L	0.917	1.00
105_L	110_A	0.916	1.00
110_A	114_I	0.916	1.00
196_D	208_S	0.913	1.00
270_F	294_G	0.913	1.00
124_Y	154_T	0.912	1.00
434_R	438_E	0.912	1.00
485_Y	488_I	0.909	1.00
765_S	771_G	0.908	1.00
360_A	363_H	0.908	1.00
794_R	798_I	0.908	1.00
709_I	713_E	0.907	1.00
142_M	155_L	0.905	1.00
712_E	715_N	0.904	1.00
728_N	758_A	0.903	1.00
214_D	326_N	0.902	1.00
761_T	764_I	0.902	1.00
491_T	498_L	0.901	1.00
555_F	576_R	0.900	1.00
674_R	694_I	0.899	1.00
695_A	733_L	0.899	1.00
629_R	659_Y	0.899	1.00
78_L	138_I	0.898	1.00
432_L	436_E	0.898	1.00
273_K	343_I	0.897	1.00
192_K	196_D	0.896	1.00
332_C	343_I	0.895	1.00
594_R	627_N	0.895	1.00
555_F	569_H	0.894	1.00
400_L	411_L	0.893	1.00
592_S	595_S	0.893	1.00
35_A	154_T	0.892	1.00
133_I	139_H	0.891	1.00
727_L	731_L	0.889	1.00
220_T	251_L	0.888	1.00
107_S	110_A	0.887	1.00
433_A	437_H	0.886	1.00
347_A	351_W	0.884	1.00
76_S	81_A	0.884	1.00
76_S	80_A	0.881	1.00
216_S	322_P	0.879	1.00
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195_F	208_S	0.877	1.00
235_S	238_K	0.877	1.00
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300_E	304_Q	0.871	1.00
770_E	774_M	0.871	1.00
734_L	750_V	0.871	1.00
733_L	736_Q	0.871	1.00
260_L	328_L	0.871	1.00
598_E	602_S	0.871	1.00
723_L	726_D	0.870	1.00
380_H	384_L	0.869	1.00
518_A	530_S	0.868	1.00
569_H	573_V	0.867	1.00
554_A	558_I	0.867	1.00
273_K	289_T	0.866	1.00
394_E	415_Q	0.866	1.00
771_G	797_R	0.866	1.00
527_A	531_L	0.862	1.00
108_L	117_A	0.862	1.00
531_L	557_L	0.862	1.00
410_Q	414_L	0.861	1.00
673_L	693_N	0.860	1.00
597_I	612_L	0.860	1.00
267_T	304_Q	0.857	1.00
60_G	64_L	0.857	1.00
545_Q	583_W	0.854	1.00
513_Q	516_Q	0.852	1.00
591_A	595_S	0.850	1.00
426_G	462_D	0.848	1.00
171_R	178_E	0.848	1.00
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474_L	478_E	0.846	1.00
733_L	737_L	0.846	1.00
427_E	430_T	0.845	1.00
769_I	772_E	0.845	1.00
498_L	503_E	0.845	1.00
495_G	514_T	0.842	1.00
640_G	649_I	0.842	1.00
731_L	753_D	0.841	1.00
601_S	634_R	0.841	1.00
205_A	209_S	0.839	1.00
475_A	478_E	0.839	1.00
696_R	700_L	0.838	1.00
513_Q	517_M	0.838	1.00
704_F	707_A	0.836	1.00
755_L	759_N	0.833	0.99
146_I	155_L	0.832	0.99
22_L	179_I	0.831	0.99
128_D	322_P	0.831	0.99
252_S	327_F	0.831	0.99
122_P	152_N	0.828	0.99
548_W	579_L	0.827	0.99
690_Q	694_I	0.827	0.99
105_L	113_F	0.827	0.99
715_N	719_R	0.826	0.99
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198_R	223_Q	0.823	0.99
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73_R	80_A	0.823	0.99
778_L	782_I	0.821	0.99
751_L	755_L	0.819	0.99
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735_N	742_G	0.818	0.99
110_A	113_F	0.818	0.99
124_Y	156_V	0.817	0.99
428_V	458_V	0.817	0.99
53_A	63_S	0.817	0.99
22_L	182_Q	0.816	0.99
581_W	586_L	0.816	0.99
467_E	471_L	0.816	0.99
407_E	410_Q	0.815	0.99
201_S	204_E	0.813	0.99
553_K	557_L	0.813	0.99
554_A	572_L	0.811	0.99
510_L	513_Q	0.811	0.99
636_E	653_N	0.811	0.99
360_A	376_I	0.809	0.99
63_S	66_E	0.808	0.99
590_E	624_D	0.807	0.99
658_I	661_Q	0.806	0.99
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759_N	767_F	0.805	0.99
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271_L	328_L	0.803	0.99
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290_G	346_A	0.801	0.99
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37_I	179_I	0.794	0.99
498_L	506_R	0.789	0.99
189_Q	192_K	0.788	0.99
66_E	69_N	0.788	0.99
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719_R	722_R	0.785	0.99
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800_R	804_Q	0.781	0.99
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748_Q	751_L	0.780	0.99
370_A	377_L	0.780	0.99
738_Y	742_G	0.779	0.99
194_F	222_L	0.779	0.99
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388_S	397_L	0.778	0.99
518_A	522_D	0.777	0.99
777_Q	781_L	0.777	0.99
544_L	548_W	0.777	0.99
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746_D	750_V	0.774	0.99
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738_Y	741_A	0.772	0.99
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59_I	66_E	0.769	0.99
280_M	320_Y	0.769	0.99
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349_E	372_M	0.763	0.99
616_I	635_L	0.763	0.99
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397_L	414_L	0.753	0.99
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799_L	804_Q	0.752	0.99
456_A	468_A	0.751	0.99
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764_I	767_F	0.747	0.99
620_L	662_M	0.746	0.99
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763_F	766_H	0.743	0.99
61_W	68_D	0.743	0.99
509_A	512_Q	0.741	0.99
81_A	127_I	0.741	0.99
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741_A	747_A	0.739	0.99
509_A	513_Q	0.738	0.99
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754_A	762_G	0.731	0.99
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282_D	295_Q	0.730	0.99
470_R	473_K	0.730	0.99
768_V	771_G	0.729	0.99
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594_R	598_E	0.729	0.99
573_V	596_G	0.728	0.99
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286_T	289_T	0.727	0.99
302_E	309_Q	0.725	0.99
772_E	778_L	0.724	0.99
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378_L	400_L	0.715	0.98
757_L	760_R	0.714	0.98
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220_T	224_L	0.713	0.98
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160_R	321_H	0.712	0.98
74_F	85_A	0.711	0.98
713_E	716_E	0.711	0.98
419_M	428_V	0.710	0.98
554_A	557_L	0.710	0.98
658_I	662_M	0.710	0.98
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454_L	457_Q	0.707	0.98
498_L	501_K	0.705	0.98
322_P	325_G	0.704	0.98
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298_L	318_F	0.703	0.98
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382_W	386_N	0.702	0.98
628_A	659_Y	0.702	0.98
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766_H	771_G	0.701	0.98
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203_I	207_E	0.690	0.98
799_L	805_H	0.690	0.98
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612_L	619_S	0.687	0.98
632_L	659_Y	0.686	0.98
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769_I	775_A	0.684	0.98
417_W	421_S	0.683	0.98
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614_M	619_S	0.681	0.98
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130_Y	139_H	0.679	0.98
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528_L	554_A	0.677	0.98
430_T	434_R	0.676	0.98
670_A	703_E	0.675	0.98
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108_L	115_E	0.666	0.98
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723_L	727_L	0.666	0.98
738_Y	750_V	0.664	0.97
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651_N	654_K	0.663	0.97
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515_E	534_Q	0.649	0.97
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572_L	576_R	0.600	0.95
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372_M	376_I	0.596	0.95
709_I	712_E	0.595	0.95
751_L	774_M	0.595	0.95
773_A	777_Q	0.594	0.95
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140_E	144_F	0.594	0.95
356_F	360_A	0.593	0.95
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594_R	619_S	0.592	0.95
108_L	111_Q	0.591	0.95
497_V	501_K	0.591	0.95
585_R	591_A	0.589	0.95
104_S	112_L	0.588	0.95
242_R	246_I	0.588	0.95
616_I	628_A	0.586	0.95
412_V	419_M	0.586	0.95
680_E	683_N	0.586	0.95
750_V	755_L	0.586	0.95
624_D	630_S	0.586	0.95
774_M	781_L	0.586	0.95
796_Q	805_H	0.586	0.95
103_A	108_L	0.585	0.95
516_Q	520_Q	0.585	0.95
721_L	724_M	0.584	0.95
571_F	575_I	0.583	0.95
411_L	414_L	0.582	0.95
361_I	373_L	0.582	0.95
735_N	738_Y	0.582	0.95
50_S	54_A	0.582	0.95
657_V	669_A	0.581	0.95
61_W	69_N	0.580	0.95
49_I	128_D	0.579	0.95
212_C	215_V	0.579	0.95
780_Q	783_Q	0.578	0.94
382_W	385_F	0.578	0.94
558_I	568_M	0.578	0.94
435_A	451_F	0.578	0.94
578_Q	582_A	0.576	0.94
689_G	693_N	0.576	0.94
480_P	491_T	0.576	0.94
73_R	78_L	0.575	0.94
111_Q	115_E	0.575	0.94
262_N	304_Q	0.575	0.94
72_E	80_A	0.574	0.94
430_T	433_A	0.574	0.94
594_R	597_I	0.574	0.94
218_W	221_A	0.573	0.94
529_W	533_Q	0.573	0.94
129_D	132_L	0.573	0.94
589_A	618_C	0.572	0.94
286_T	291_E	0.572	0.94
281_N	317_W	0.572	0.94
713_E	717_N	0.572	0.94
488_I	514_T	0.571	0.94
542_G	551_Q	0.570	0.94
771_G	777_Q	0.570	0.94
768_V	772_E	0.570	0.94
469_E	498_L	0.569	0.94
374_R	400_L	0.569	0.94
429_N	458_V	0.568	0.94
71_Q	77_Y	0.566	0.94
78_L	81_A	0.566	0.94
452_N	456_A	0.565	0.94
362_H	395_E	0.565	0.94
769_I	774_M	0.565	0.94
639_L	643_K	0.564	0.94
775_A	780_Q	0.564	0.94
484_F	520_Q	0.563	0.94
349_E	353_A	0.563	0.94
60_G	123_L	0.563	0.94
19_R	22_L	0.563	0.94
620_L	655_V	0.563	0.94
490_A	493_V	0.562	0.94
251_L	323_L	0.562	0.94
52_W	124_Y	0.561	0.94
730_N	735_N	0.561	0.94
381_A	393_L	0.560	0.94
408_N	411_L	0.559	0.93
456_A	459_A	0.559	0.93
454_L	459_A	0.559	0.93
766_H	770_E	0.558	0.93
511_M	533_Q	0.558	0.93
547_A	558_I	0.558	0.93
527_A	557_L	0.556	0.93
686_F	689_G	0.556	0.93
639_L	642_G	0.555	0.93
515_E	527_A	0.555	0.93
593_A	596_G	0.554	0.93
105_L	111_Q	0.554	0.93
514_T	519_R	0.554	0.93
60_G	65_D	0.554	0.93
778_L	783_Q	0.553	0.93
384_L	393_L	0.553	0.93
773_A	779_R	0.553	0.93
528_L	558_I	0.553	0.93
733_L	738_Y	0.552	0.93
574_R	578_Q	0.552	0.93
620_L	632_L	0.551	0.93
691_W	713_E	0.551	0.93
248_A	251_L	0.551	0.93
693_N	696_R	0.549	0.93
255_L	324_F	0.548	0.93
794_R	805_H	0.548	0.93
612_L	638_L	0.547	0.93
60_G	63_S	0.547	0.93
471_L	474_L	0.547	0.93
680_E	684_N	0.546	0.93
72_E	77_Y	0.546	0.93
764_I	768_V	0.545	0.93
653_N	676_T	0.545	0.93
545_Q	548_W	0.545	0.93
109_F	113_F	0.544	0.93
742_G	754_A	0.543	0.92
765_S	805_H	0.542	0.92
514_T	518_A	0.541	0.92
431_L	438_E	0.541	0.92
635_L	639_L	0.541	0.92
705_E	708_E	0.541	0.92
104_S	108_L	0.541	0.92
103_A	106_T	0.541	0.92
742_G	746_D	0.541	0.92
593_A	597_I	0.540	0.92
735_N	754_A	0.540	0.92
691_W	710_V	0.540	0.92
655_V	658_I	0.540	0.92
589_A	593_A	0.539	0.92
409_P	439_I	0.539	0.92
758_A	770_E	0.538	0.92
194_F	223_Q	0.537	0.92
732_L	737_L	0.536	0.92
29_A	154_T	0.536	0.92
649_I	653_N	0.536	0.92
341_P	345_R	0.536	0.92
450_E	454_L	0.536	0.92
488_I	491_T	0.536	0.92
415_Q	422_Q	0.535	0.92
694_I	710_V	0.535	0.92
272_L	328_L	0.535	0.92
710_V	714_L	0.535	0.92
48_L	181_S	0.535	0.92
65_D	68_D	0.534	0.92
544_L	583_W	0.534	0.92
209_S	212_C	0.533	0.92
693_N	698_Q	0.532	0.92
556_Q	559_N	0.532	0.92
357_P	363_H	0.532	0.92
771_G	794_R	0.531	0.92
218_W	254_Y	0.531	0.92
287_R	354_Q	0.530	0.92
224_L	228_S	0.530	0.92
109_F	112_L	0.529	0.91
643_K	646_S	0.528	0.91
488_I	518_A	0.528	0.91
794_R	803_N	0.528	0.91
287_R	350_S	0.527	0.91
144_F	147_R	0.526	0.91
654_K	673_L	0.526	0.91
398_K	419_M	0.524	0.91
566_L	569_H	0.524	0.91
551_Q	579_L	0.524	0.91
472_A	490_A	0.524	0.91
74_F	80_A	0.523	0.91
767_F	781_L	0.523	0.91
416_A	428_V	0.523	0.91
380_H	396_S	0.522	0.91
75_A	80_A	0.522	0.91
71_Q	76_S	0.522	0.91
75_A	82_V	0.522	0.91
758_A	767_F	0.521	0.91
722_R	725_S	0.521	0.91
333_Q	338_A	0.521	0.91
657_V	693_N	0.520	0.91
773_A	776_Q	0.520	0.91
440_K	448_H	0.520	0.91
186_F	219_A	0.519	0.91
374_R	378_L	0.519	0.91
676_T	679_P	0.519	0.91
762_G	767_F	0.518	0.91
775_A	795_A	0.518	0.91
511_M	534_Q	0.517	0.91
617_Q	621_A	0.517	0.91
138_I	141_S	0.517	0.91
613_A	617_Q	0.517	0.91
527_A	530_S	0.516	0.90
732_L	770_E	0.516	0.90
284_L	288_V	0.516	0.90
195_F	198_R	0.516	0.90
72_E	76_S	0.514	0.90
402_W	411_L	0.513	0.90
228_S	232_N	0.513	0.90
355_G	359_E	0.512	0.90
80_A	83_Q	0.512	0.90
195_F	222_L	0.512	0.90
755_L	767_F	0.512	0.90
613_A	618_C	0.512	0.90
731_L	757_L	0.512	0.90
617_Q	620_L	0.512	0.90
309_Q	318_F	0.511	0.90
106_T	109_F	0.511	0.90
16_T	190_E	0.510	0.90
456_A	475_A	0.510	0.90
524_W	527_A	0.509	0.90
394_E	419_M	0.508	0.90
568_M	571_F	0.507	0.90
544_L	579_L	0.507	0.90
302_E	318_F	0.507	0.90
507_S	537_I	0.507	0.90
714_L	722_R	0.506	0.90
22_L	25_K	0.506	0.90
276_I	332_C	0.506	0.90
487_R	490_A	0.506	0.90
418_L	421_S	0.505	0.89
370_A	373_L	0.505	0.89
718_A	723_L	0.504	0.89
731_L	734_L	0.504	0.89
773_A	778_L	0.504	0.89
385_F	393_L	0.504	0.89
409_P	413_L	0.504	0.89
198_R	226_A	0.503	0.89
63_S	67_G	0.502	0.89
218_W	222_L	0.502	0.89
487_R	492_S	0.502	0.89
433_A	436_E	0.501	0.89
724_M	728_N	0.501	0.89
635_L	652_A	0.501	0.89
22_L	181_S	0.501	0.89
557_L	560_E	0.501	0.89
746_D	758_A	0.500	0.89

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1z6tA	1	0.4761	100	0.712	Contact Map
2a5yB	2	0.3807	100	0.769	Contact Map
2qenA	1	0.3441	100	0.799	Contact Map
1hz4A	2	0.4062	100	0.801	Contact Map
1w3bA	2	0.4295	99.9	0.816	Contact Map
3sf4A	1	0.3718	99.9	0.818	Contact Map
2fnaA	1	0.3352	99.9	0.819	Contact Map
4ui9O	1	0.6204	99.9	0.821	Contact Map
3sfzA	1	0.7192	99.9	0.827	Contact Map
3ro2A	1	0.3407	99.9	0.829	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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