GREMLIN Database
FHUB - Iron(3+)-hydroxamate import system permease protein FhuB
UniProt: P06972 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG10303
Length: 660 (645)
Sequences: 340 (247)
Seq/√Len: 9.7

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
64_I191_V5.6601.00
603_F612_I3.9460.98
410_I569_L3.9330.98
89_E491_T3.7820.98
398_L618_G3.6020.97
137_W141_L3.5550.97
71_G247_L3.4900.97
176_F636_Q3.4620.96
195_W199_L3.3920.96
628_G639_A3.2140.95
158_G476_P3.2030.94
265_A270_A3.0530.93
129_G241_I3.0050.92
179_S488_T2.9920.92
155_L508_V2.9030.91
157_C649_P2.8970.91
33_P37_W2.8580.90
76_G90_P2.8570.90
365_A394_I2.8410.90
44_P51_Q2.7780.89
486_L620_L2.6500.86
268_L279_L2.6470.86
403_M576_L2.6460.86
102_G120_A2.6290.86
64_I68_V2.6120.85
405_A621_L2.5800.85
90_P262_P2.5760.85
541_C646_I2.5590.84
593_M644_T2.4920.82
546_T606_T2.4430.81
97_T508_V2.4240.81
152_V576_L2.3960.80
353_A356_V2.3620.79
64_I251_V2.3350.78
396_A519_A2.3240.78
354_G615_L2.3050.77
76_G262_P2.2990.77
581_T628_G2.2730.76
295_I465_I2.2710.76
427_I447_F2.2390.75
393_R625_D2.2370.75
32_L37_W2.2210.74
437_L441_L2.2030.74
359_L363_V2.1950.73
155_L255_G2.1810.73
434_G437_L2.1440.71
127_V361_A2.1290.71
67_L206_L2.1090.70
163_L496_M2.0940.70
56_Y578_A2.0820.69
364_V532_V2.0430.68
174_S291_S2.0420.68
89_E179_S2.0380.67
161_N411_I2.0340.67
131_I268_L2.0280.67
68_V247_L2.0020.66
566_R629_R1.9760.65
40_A44_P1.9710.65
79_F293_Q1.9660.64
406_V614_A1.9310.63
52_M370_R1.9160.62
419_M656_R1.8830.61
434_G651_F1.8720.61
125_A546_T1.8060.58
280_A644_T1.8060.58
362_V395_M1.8000.57
627_C642_L1.7990.57
70_A281_S1.7910.57
431_A454_G1.7820.57
411_I427_I1.7730.56
156_Y389_W1.7650.56
395_M528_G1.7620.56
95_V237_L1.7580.55
630_M636_Q1.7470.55
75_V639_A1.7380.55
196_P517_Y1.7380.55
433_F657_K1.7350.54
159_A646_I1.7310.54
37_W51_Q1.7170.54
176_F431_A1.7110.53
391_W521_D1.7090.53
361_A533_I1.6850.52
653_Y657_K1.6780.52
131_I157_C1.6740.52
83_L90_P1.6630.51
82_V236_A1.6630.51
461_T484_M1.6600.51
227_L232_A1.6600.51
180_T652_I1.6530.51
307_T311_T1.6490.51
125_A216_G1.6470.50
64_I190_G1.6420.50
129_G648_A1.6390.50
407_A577_T1.6280.50
566_R638_P1.6230.49
638_P643_S1.6200.49
225_L558_V1.6200.49
306_S309_S1.6170.49
454_G656_R1.6080.49
18_I537_I1.6080.49
469_A654_L1.6000.48
63_A191_V1.6000.48
289_W295_I1.5910.48
453_A651_F1.5850.48
194_L251_V1.5730.47
248_V500_S1.5720.47
610_I646_I1.5690.47
488_T642_L1.5640.47
129_G154_S1.5640.47
357_L533_I1.5630.47
253_I494_L1.5630.47
76_G83_L1.5620.47
195_W536_A1.5370.46
356_V560_M1.5370.46
59_L176_F1.5330.45
83_L172_L1.5330.45
147_I488_T1.5260.45
511_W651_F1.5200.45
91_T423_E1.5190.45
65_S290_L1.5150.45
581_T639_A1.5140.45
159_A655_L1.5090.44
176_F518_N1.5050.44
90_P94_G1.5030.44
316_A651_F1.5020.44
125_A648_A1.5020.44
71_G175_M1.5020.44
496_M606_T1.5010.44
89_E169_H1.5000.44
318_L548_L1.4990.44
129_G620_L1.4940.44
102_G411_I1.4850.43
20_A23_L1.4820.43
567_I631_V1.4790.43
58_L296_L1.4760.43
392_P625_D1.4730.43
423_E458_A1.4700.43
19_V522_A1.4690.43
532_V536_A1.4680.42
270_A275_P1.4640.42
277_L584_I1.4610.42
588_S620_L1.4530.42
305_V310_V1.4500.42
33_P36_Q1.4470.42
174_S179_S1.4470.42
163_L180_T1.4430.41
218_D280_A1.4420.41
89_E293_Q1.4390.41
108_L133_F1.4340.41
144_V561_A1.4340.41
91_T494_L1.4320.41
316_A628_G1.4290.41
147_I386_L1.4290.41
28_F463_L1.4240.41
261_A311_T1.4240.41
237_L642_L1.4230.40
79_F96_A1.4210.40
175_M215_M1.4120.40
144_V620_L1.4060.40
268_L286_L1.4060.40
126_C606_T1.3980.39
356_V646_I1.3950.39
48_V429_S1.3890.39
44_P361_A1.3780.39
316_A454_G1.3760.38
267_M320_L1.3590.38
257_I509_L1.3580.38
107_T151_L1.3510.37
389_W403_M1.3490.37
76_G94_G1.3480.37
517_Y626_W1.3470.37
313_L400_A1.3390.37
19_V22_A1.3370.37
502_D637_I1.3360.37
134_G280_A1.3340.37
102_G195_W1.3190.36
65_S296_L1.3140.36
36_Q48_V1.3120.36
123_A538_T1.3020.35
171_Q175_M1.3010.35
431_A469_A1.3010.35
96_A162_Q1.2980.35
75_V95_V1.2910.35
364_V368_F1.2900.35
611_V618_G1.2870.35
629_R643_S1.2830.35
65_S293_Q1.2810.34
539_P607_M1.2810.34
43_S547_I1.2800.34
519_A540_L1.2760.34
590_V596_H1.2760.34
610_I615_L1.2760.34
219_D245_A1.2690.34
555_A560_M1.2680.34
410_I471_R1.2640.34
608_P616_V1.2600.34
290_L464_I1.2600.34
355_G359_L1.2590.34
247_L260_F1.2570.34
195_W362_V1.2520.33
545_L610_I1.2490.33
311_T318_L1.2460.33
149_A270_A1.2450.33
304_E613_S1.2430.33
137_W389_W1.2420.33
166_I651_F1.2380.33
104_T218_D1.2360.33
488_T491_T1.2310.32
166_I171_Q1.2240.32
91_T424_V1.2210.32
253_I539_P1.2210.32
133_F461_T1.2200.32
125_A654_L1.2190.32
219_D633_F1.2110.32
73_G289_W1.2080.32
273_L276_R1.2020.31
260_F636_Q1.2000.31
429_S450_L1.2000.31
119_F612_I1.1990.31
126_C584_I1.1980.31
229_L652_I1.1890.31
570_L628_G1.1820.31
113_G116_A1.1820.31
83_L262_P1.1810.31
159_A396_A1.1780.30
530_V579_T1.1770.30
100_Q635_F1.1760.30
233_R415_T1.1730.30
61_R292_D1.1730.30
537_I575_C1.1720.30
469_A636_Q1.1620.30
133_F424_V1.1620.30
170_D636_Q1.1580.30
89_E488_T1.1570.30
265_A283_I1.1550.30
35_S352_L1.1550.30
605_R608_P1.1540.29
365_A470_G1.1540.29
21_T232_A1.1530.29
396_A548_L1.1500.29
565_T645_F1.1500.29
66_L286_L1.1480.29
145_T154_S1.1460.29
632_L636_Q1.1420.29
55_H409_C1.1390.29
156_Y293_Q1.1370.29
79_F162_Q1.1370.29
516_T628_G1.1360.29
151_L302_W1.1360.29
130_L157_C1.1360.29
186_T651_F1.1350.29
149_A441_L1.1310.29
147_I492_M1.1270.28
298_L529_I1.1250.28
89_E104_T1.1250.28
257_I383_L1.1240.28
83_L641_L1.1230.28
463_L528_G1.1180.28
105_V109_W1.1170.28
16_L355_G1.1150.28
118_Q648_A1.1150.28
89_E527_T1.1130.28
488_T645_F1.1130.28
88_A550_L1.1120.28
113_G296_L1.1120.28
306_S484_M1.1120.28
96_A655_L1.1110.28
174_S547_I1.1100.28
30_Q122_Q1.1070.28
144_V513_S1.1060.28
34_R136_A1.1020.28
508_V620_L1.0990.27
465_I547_I1.0980.27
206_L360_M1.0970.27
12_L355_G1.0940.27
89_E468_A1.0930.27
157_C651_F1.0930.27
73_G163_L1.0880.27
389_W474_F1.0820.27
21_T624_A1.0800.27
501_G594_A1.0780.27
629_R638_P1.0780.27
104_T176_F1.0770.27
104_T484_M1.0760.27
400_A431_A1.0750.27
23_L562_L1.0690.26
469_A507_Q1.0690.26
196_P214_L1.0680.26
313_L637_I1.0670.26
79_F95_V1.0670.26
235_A541_C1.0660.26
176_F654_L1.0650.26
19_V354_G1.0650.26
359_L364_V1.0650.26
203_M235_A1.0630.26
139_K644_T1.0620.26
343_E347_V1.0620.26
320_L453_A1.0610.26
206_L261_A1.0580.26
233_R580_A1.0570.26
167_F651_F1.0560.26
272_R275_P1.0560.26
89_E327_R1.0550.26
179_S635_F1.0530.26
133_F419_M1.0490.26
625_D639_A1.0480.26
14_A360_M1.0470.26
88_A233_R1.0460.26
63_A353_A1.0450.26
561_A573_A1.0440.26
107_T125_A1.0390.25
89_E540_L1.0390.25
28_F33_P1.0360.25
125_A414_L1.0360.25
566_R643_S1.0360.25
639_A651_F1.0350.25
232_A464_I1.0340.25
18_I22_A1.0320.25
123_A610_I1.0320.25
423_E624_A1.0320.25
190_G250_A1.0290.25
174_S248_V1.0270.25
441_L525_W1.0260.25
89_E649_P1.0260.25
191_V196_P1.0240.25
61_R94_G1.0240.25
121_A309_S1.0230.25
71_G243_I1.0210.25
61_R76_G1.0210.25
273_L320_L1.0200.25
79_F89_E1.0190.25
151_L180_T1.0190.25
261_A275_P1.0180.25
21_T123_A1.0160.25
146_L465_I1.0150.25
61_R266_K1.0150.25
431_A649_P1.0140.25
314_I597_I1.0070.24
311_T584_I1.0070.24
170_D651_F1.0070.24
100_Q434_G1.0060.24
137_W490_F1.0040.24
285_A532_V1.0020.24
89_E539_P1.0020.24
167_F234_L1.0010.24
84_R139_K1.0000.24
113_G159_A0.9990.24
113_G260_F0.9980.24
131_I509_L0.9980.24
218_D490_F0.9970.24
105_V613_S0.9960.24
601_M609_H0.9960.24
508_V609_H0.9950.24
100_Q637_I0.9910.24
437_L646_I0.9910.24
239_L427_I0.9890.24
96_A484_M0.9830.23
187_D552_G0.9810.23
353_A537_I0.9800.23
89_E244_S0.9780.23
272_R310_V0.9770.23
255_G405_A0.9770.23
596_H650_Y0.9760.23
159_A620_L0.9760.23
118_Q279_L0.9740.23
427_I467_I0.9730.23
188_W258_G0.9730.23
51_Q55_H0.9670.23
255_G326_L0.9660.23
65_S493_L0.9640.23
147_I546_T0.9630.23
239_L533_I0.9620.23
170_D498_Q0.9570.23
358_L614_A0.9560.23
79_F403_M0.9560.23
215_M290_L0.9530.23
59_L609_H0.9530.23
464_I536_A0.9520.23
435_V496_M0.9510.22
179_S651_F0.9510.22
114_A492_M0.9500.22
167_F218_D0.9500.22
420_A476_P0.9480.22
91_T429_S0.9480.22
196_P377_W0.9450.22
61_R543_R0.9440.22
15_L21_T0.9440.22
66_L285_A0.9430.22
628_G637_I0.9430.22
329_I560_M0.9420.22
129_G142_S0.9410.22
372_A377_W0.9410.22
316_A556_R0.9410.22
534_L572_L0.9400.22
149_A313_L0.9400.22
370_R374_G0.9400.22
65_S148_L0.9390.22
48_V622_V0.9380.22
177_L253_I0.9370.22
83_L94_G0.9370.22
192_E463_L0.9360.22
132_V248_V0.9300.22
61_R90_P0.9290.22
385_D416_G0.9250.22
131_I153_V0.9230.22
94_G262_P0.9230.22
431_A630_M0.9230.22
125_A238_S0.9210.22
160_I419_M0.9180.21
434_G453_A0.9170.21
161_N227_L0.9160.21
152_V322_L0.9150.21
538_T614_A0.9150.21
517_Y628_G0.9120.21
232_A583_T0.9110.21
316_A498_Q0.9100.21
104_T492_M0.9080.21
465_I479_M0.9060.21
170_D637_I0.9060.21
391_W525_W0.9050.21
12_L590_V0.9030.21
315_G638_P0.9010.21
21_T537_I0.9000.21
203_M282_L0.8980.21
192_E195_W0.8970.21
144_V151_L0.8960.21
199_L471_R0.8960.21
158_G637_I0.8950.21
18_I30_Q0.8950.21
311_T504_R0.8940.21
151_L504_R0.8940.21
255_G462_L0.8930.21
377_W475_S0.8920.21
480_L643_S0.8910.21
304_E645_F0.8910.21
499_A557_A0.8910.21
89_E157_C0.8900.21
106_T201_G0.8880.21
368_F529_I0.8880.21
369_G641_L0.8880.21
141_L652_I0.8870.21
81_Q276_R0.8870.21
141_L657_K0.8840.20
211_P240_A0.8820.20
594_A617_G0.8820.20
61_R413_R0.8810.20
53_I62_L0.8780.20
96_A515_S0.8780.20
127_V568_A0.8780.20
537_I622_V0.8780.20
360_M568_A0.8760.20
78_L513_S0.8760.20
141_L146_L0.8740.20
459_A622_V0.8740.20
262_P594_A0.8730.20
143_P225_L0.8720.20
581_T626_W0.8710.20
151_L414_L0.8690.20
450_L508_V0.8690.20
210_R578_A0.8690.20
42_W355_G0.8680.20
101_L431_A0.8670.20
233_R629_R0.8670.20
100_Q423_E0.8650.20
45_D528_G0.8650.20
196_P636_Q0.8640.20
272_R531_M0.8620.20
326_L605_R0.8600.20
576_L650_Y0.8600.20
35_S360_M0.8600.20
26_M657_K0.8590.20
266_K543_R0.8570.20
54_F498_Q0.8570.20
97_T280_A0.8550.20
517_Y639_A0.8540.20
313_L619_L0.8520.20
586_P589_F0.8510.19
285_A369_G0.8500.19
180_T491_T0.8500.19
402_V406_V0.8490.19
419_M502_D0.8480.19
79_F173_Q0.8470.19
259_L602_G0.8460.19
152_V484_M0.8420.19
406_V534_L0.8390.19
419_M630_M0.8380.19
248_V454_G0.8380.19
562_L608_P0.8350.19
78_L205_T0.8350.19
23_L487_S0.8350.19
416_G544_W0.8340.19
146_L394_I0.8310.19
364_V606_T0.8310.19
264_L295_I0.8290.19
89_E144_V0.8270.19
34_R37_W0.8250.19
286_L298_L0.8250.19
197_Q255_G0.8230.19
177_L648_A0.8220.19
52_M547_I0.8200.19
76_G400_A0.8200.19
244_S298_L0.8190.19
322_L629_R0.8190.19
235_A365_A0.8190.19
402_V579_T0.8170.19
74_L281_S0.8160.19
141_L490_F0.8160.19
281_S451_L0.8160.19
68_V429_S0.8150.18
179_S491_T0.8120.18
179_S645_F0.8100.18
176_F312_A0.8100.18
154_S176_F0.8100.18
57_S187_D0.8100.18
399_F524_V0.8100.18
132_V153_V0.8080.18
445_N479_M0.8080.18
152_V624_A0.8050.18
45_D136_A0.8030.18
307_T396_A0.8030.18
52_M171_Q0.8030.18
108_L638_P0.8030.18
151_L582_M0.8020.18
471_R538_T0.8010.18
16_L438_M0.7990.18
282_L427_I0.7990.18
304_E488_T0.7980.18
432_A576_L0.7970.18
309_S313_L0.7970.18
316_A573_A0.7930.18
66_L272_R0.7920.18
71_G267_M0.7900.18
57_S652_I0.7890.18
459_A623_F0.7890.18
196_P519_A0.7890.18
68_V639_A0.7870.18
410_I574_A0.7870.18
16_L28_F0.7850.18
494_L654_L0.7840.18
439_L503_P0.7800.18
590_V600_M0.7790.18
236_A512_I0.7780.17
348_L354_G0.7760.17
349_A529_I0.7750.17
123_A202_V0.7750.17
353_A615_L0.7740.17
209_L545_L0.7720.17
174_S630_M0.7720.17
66_L159_A0.7720.17
61_R83_L0.7710.17
233_R480_L0.7700.17
64_I573_A0.7700.17
163_L398_L0.7690.17
512_I573_A0.7690.17
143_P233_R0.7680.17
172_L207_L0.7670.17
116_A531_M0.7670.17
127_V206_L0.7660.17
177_L475_S0.7660.17
486_L521_D0.7640.17
15_L278_M0.7640.17
352_L360_M0.7630.17
245_A547_I0.7620.17
225_L233_R0.7620.17
262_P281_S0.7610.17
636_Q642_L0.7590.17
169_H179_S0.7590.17
99_A285_A0.7580.17
270_A279_L0.7580.17
151_L616_V0.7570.17
512_I547_I0.7560.17
48_V616_V0.7560.17
497_L503_P0.7560.17
211_P629_R0.7540.17
282_L529_I0.7540.17
38_A41_A0.7540.17
95_V458_A0.7530.17
214_L546_T0.7520.17
312_A320_L0.7500.17
59_L146_L0.7500.17
18_I557_A0.7500.17
186_T309_S0.7490.17
626_W639_A0.7490.17
491_T565_T0.7490.17
84_R323_L0.7470.17
302_W446_A0.7470.17
268_L314_I0.7470.17
166_I354_G0.7470.17
86_P580_A0.7450.17
249_N279_L0.7440.17
479_M648_A0.7440.17
498_Q651_F0.7430.17
109_W493_L0.7420.17
200_G253_I0.7370.16
105_V355_G0.7360.16
154_S179_S0.7350.16
19_V352_L0.7340.16
197_Q310_V0.7340.16
326_L478_R0.7300.16
321_W407_A0.7290.16
180_T488_T0.7290.16
18_I623_F0.7280.16
159_A444_G0.7280.16
101_L325_R0.7270.16
21_T360_M0.7270.16
574_A639_A0.7240.16
120_A651_F0.7240.16
146_L187_D0.7240.16
148_L648_A0.7190.16
62_L485_A0.7180.16
577_T641_L0.7180.16
74_L524_V0.7170.16
48_V257_I0.7150.16
54_F78_L0.7140.16
414_L618_G0.7140.16
536_A597_I0.7130.16
19_V353_A0.7130.16
289_W434_G0.7120.16
393_R431_A0.7110.16
587_L633_F0.7100.16
172_L485_A0.7100.16
398_L636_Q0.7080.16
309_S629_R0.7080.16
291_S620_L0.7080.16
182_T472_G0.7080.16
198_L262_P0.7060.16
403_M531_M0.7050.16
578_A655_L0.7030.16
316_A436_V0.7030.16
141_L616_V0.7020.16
133_F224_N0.7010.16
120_A446_A0.6990.16
130_L395_M0.6980.15
342_A579_T0.6970.15
232_A571_L0.6960.15
292_D413_R0.6950.15
86_P141_L0.6950.15
549_P580_A0.6940.15
480_L580_A0.6920.15
42_W353_A0.6910.15
142_S581_T0.6900.15
436_V494_L0.6890.15
415_T550_L0.6880.15
172_L389_W0.6880.15
73_G359_L0.6880.15
49_I424_V0.6880.15
145_T323_L0.6870.15
205_T531_M0.6860.15
64_I424_V0.6860.15
125_A174_S0.6850.15
40_A587_L0.6850.15
316_A517_Y0.6840.15
151_L423_E0.6840.15
153_V177_L0.6830.15
169_H637_I0.6810.15
633_F648_A0.6810.15
501_G578_A0.6800.15
35_S123_A0.6790.15
206_L209_L0.6780.15
119_F140_R0.6780.15
582_M588_S0.6770.15
68_V508_V0.6770.15
491_T613_S0.6750.15
305_V610_I0.6730.15
318_L504_R0.6730.15
42_W633_F0.6720.15
76_G594_A0.6710.15
643_S657_K0.6700.15
73_G268_L0.6700.15
521_D533_I0.6690.15
180_T289_W0.6680.15
13_L28_F0.6680.15
429_S491_T0.6680.15
16_L370_R0.6680.15
532_V613_S0.6670.15
187_D369_G0.6660.15
18_I34_R0.6660.15
169_H429_S0.6660.15
397_A641_L0.6660.15
17_V341_A0.6650.15
14_A352_L0.6640.15
138_G638_P0.6630.15
237_L646_I0.6620.15
97_T215_M0.6610.15
168_H636_Q0.6610.15
302_W305_V0.6600.15
68_V477_H0.6600.15
102_G371_D0.6580.15
108_L164_L0.6580.15
263_L400_A0.6570.15
14_A560_M0.6570.15
411_I621_L0.6560.15
84_R474_F0.6560.15
90_P594_A0.6550.15
166_I234_L0.6550.15
66_L561_A0.6540.14
469_A561_A0.6540.14
574_A581_T0.6530.14
201_G319_L0.6510.14
89_E506_A0.6490.14
120_A305_V0.6490.14
173_Q636_Q0.6480.14
626_W650_Y0.6480.14
238_S278_M0.6460.14
153_V341_A0.6460.14
388_P471_R0.6450.14
18_I657_K0.6450.14
522_A532_V0.6450.14
350_F612_I0.6440.14
132_V427_I0.6430.14
232_A289_W0.6420.14
234_L536_A0.6410.14
127_V286_L0.6410.14
639_A647_G0.6400.14
137_W218_D0.6400.14
410_I429_S0.6400.14
550_L587_L0.6400.14
386_L629_R0.6370.14
171_Q402_V0.6350.14
356_V360_M0.6340.14
579_T593_M0.6340.14
133_F519_A0.6340.14
179_S309_S0.6310.14
419_M504_R0.6310.14
465_I618_G0.6300.14
289_W490_F0.6300.14
394_I622_V0.6300.14
41_A616_V0.6290.14
478_R485_A0.6280.14
90_P168_H0.6280.14
411_I414_L0.6270.14
130_L204_L0.6270.14
93_L188_W0.6260.14
354_G361_A0.6240.14
152_V403_M0.6240.14
156_Y229_L0.6230.14
398_L590_V0.6230.14
65_S356_V0.6220.14
322_L480_L0.6220.14
564_P657_K0.6210.14
186_T648_A0.6190.14
423_E582_M0.6190.14
19_V607_M0.6170.14
460_V575_C0.6160.14
384_E613_S0.6160.14
64_I187_D0.6150.14
384_E410_I0.6140.14
207_L279_L0.6140.14
97_T620_L0.6140.14
596_H626_W0.6140.14
95_V432_A0.6130.14
117_S279_L0.6130.14
168_H201_G0.6130.14
151_L170_D0.6120.14
169_H291_S0.6110.14
261_A550_L0.6110.14
161_N613_S0.6110.14
77_V402_V0.6110.14
338_D414_L0.6100.14
18_I202_V0.6090.14
130_L610_I0.6080.13
553_D560_M0.6070.13
598_A646_I0.6070.13
286_L366_L0.6070.13
316_A429_S0.6050.13
13_L353_A0.6050.13
62_L298_L0.6050.13
111_I247_L0.6040.13
335_K360_M0.6040.13
292_D543_R0.6040.13
416_G548_L0.6040.13
95_V656_R0.6040.13
18_I334_M0.6030.13
180_T434_G0.6030.13
197_Q276_R0.6020.13
87_L545_L0.6020.13
228_A413_R0.6020.13
156_Y320_L0.6000.13
20_A236_A0.6000.13
70_A262_P0.6000.13
389_W576_L0.6000.13
261_A307_T0.5990.13
223_R265_A0.5980.13
84_R240_A0.5970.13
82_V512_I0.5960.13
42_W290_L0.5950.13
134_G146_L0.5950.13
88_A629_R0.5940.13
613_S655_L0.5930.13
259_L524_V0.5930.13
28_F349_A0.5910.13
440_F502_D0.5910.13
381_A437_L0.5900.13
250_A347_V0.5900.13
79_F237_L0.5900.13
158_G248_V0.5900.13
429_S565_T0.5890.13
78_L621_L0.5860.13
566_R599_R0.5850.13
438_M453_A0.5850.13
276_R443_P0.5850.13
180_T651_F0.5840.13
356_V575_C0.5840.13
64_I234_L0.5840.13
225_L415_T0.5830.13
161_N224_N0.5810.13
148_L633_F0.5810.13
264_L289_W0.5810.13
276_R316_A0.5810.13
157_C244_S0.5800.13
624_A652_I0.5800.13
13_L19_V0.5790.13
545_L602_G0.5790.13
410_I541_C0.5790.13
519_A572_L0.5780.13
52_M416_G0.5780.13
604_R613_S0.5770.13
223_R427_I0.5770.13
91_T491_T0.5760.13
147_I406_V0.5760.13
248_V570_L0.5760.13
151_L642_L0.5730.13
57_S305_V0.5730.13
283_I302_W0.5720.13
65_S557_A0.5720.13
403_M504_R0.5720.13
110_A448_G0.5720.13
67_L198_L0.5720.13
202_V360_M0.5710.13
332_P497_L0.5710.13
127_V358_L0.5700.13
305_V475_S0.5680.13
516_T639_A0.5680.13
28_F41_A0.5680.13
547_I556_R0.5680.13
95_V596_H0.5670.13
65_S108_L0.5670.13
73_G276_R0.5670.13
13_L529_I0.5670.13
63_A604_R0.5670.13
218_D314_I0.5660.13
313_L573_A0.5660.13
59_L654_L0.5660.13
156_Y603_F0.5650.13
151_L507_Q0.5650.13
147_I535_L0.5650.13
25_W203_M0.5640.13
27_N187_D0.5640.13
76_G84_R0.5630.13
167_F174_S0.5620.13
175_M498_Q0.5620.13
322_L400_A0.5620.13
116_A312_A0.5610.13
498_Q570_L0.5610.13
179_S576_L0.5600.13
549_P615_L0.5590.12
168_H262_P0.5590.12
239_L297_W0.5580.12
451_L455_S0.5570.12
176_F450_L0.5570.12
404_L427_I0.5550.12
137_W143_P0.5550.12
168_H171_Q0.5540.12
199_L290_L0.5540.12
584_I587_L0.5530.12
149_A363_V0.5530.12
241_I323_L0.5520.12
421_S495_M0.5500.12
476_P569_L0.5490.12
470_G488_T0.5490.12
561_A571_L0.5490.12
319_L544_W0.5480.12
391_W508_V0.5470.12
163_L584_I0.5460.12
105_V529_I0.5450.12
176_F642_L0.5450.12
117_S324_P0.5440.12
105_V108_L0.5430.12
216_G280_A0.5430.12
291_S324_P0.5430.12
198_L575_C0.5410.12
548_L599_R0.5410.12
108_L151_L0.5410.12
383_L540_L0.5400.12
217_L406_V0.5400.12
100_Q145_T0.5390.12
467_I583_T0.5390.12
581_T651_F0.5370.12
158_G428_S0.5370.12
350_F361_A0.5350.12
339_R657_K0.5350.12
346_H349_A0.5340.12
236_A263_L0.5340.12
75_V244_S0.5320.12
131_I597_I0.5320.12
234_L597_I0.5320.12
265_A455_S0.5300.12
154_S469_A0.5290.12
78_L128_V0.5290.12
335_K565_T0.5280.12
134_G352_L0.5270.12
491_T495_M0.5260.12
362_V533_I0.5260.12
61_R262_P0.5250.12
351_A463_L0.5250.12
59_L192_E0.5240.12
356_V460_V0.5240.12
141_L154_S0.5240.12
361_A619_L0.5240.12
36_Q353_A0.5230.12
225_L544_W0.5230.12
143_P423_E0.5220.12
486_L636_Q0.5220.12
57_S76_G0.5220.12
68_V601_M0.5210.12
487_S573_A0.5200.12
406_V646_I0.5200.12
489_A534_L0.5180.12
434_G535_L0.5180.12
392_P516_T0.5180.12
456_L536_A0.5180.12
528_G596_H0.5170.12
324_P478_R0.5170.12
487_S638_P0.5160.12
624_A640_G0.5160.12
174_S635_F0.5160.12
125_A331_A0.5160.12
102_G267_M0.5150.12
154_S450_L0.5150.12
277_L427_I0.5150.12
257_I578_A0.5150.12
176_F523_Q0.5140.12
144_V486_L0.5140.12
103_I477_H0.5140.12
113_G138_G0.5130.12
176_F210_R0.5130.12
174_S309_S0.5130.12
83_L588_S0.5130.12
566_R577_T0.5120.12
146_L439_L0.5120.12
90_P198_L0.5120.12
479_M618_G0.5120.12
304_E643_S0.5120.12
78_L176_F0.5110.12
264_L487_S0.5110.12
56_Y166_I0.5110.12
151_L593_M0.5100.12
89_E180_T0.5090.12
451_L601_M0.5090.12
86_P480_L0.5090.12
458_A624_A0.5090.12
131_I623_F0.5080.12
296_L307_T0.5080.12
188_W309_S0.5070.11
445_N651_F0.5070.11
260_F465_I0.5070.11
441_L651_F0.5070.11
180_T535_L0.5070.11
260_F461_T0.5070.11
17_V362_V0.5070.11
33_P601_M0.5060.11
487_S643_S0.5050.11
83_L86_P0.5050.11
128_V452_P0.5040.11
119_F484_M0.5040.11
96_A125_A0.5030.11
132_V428_S0.5010.11
143_P311_T0.5000.11
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2qi9A 2 0.4864 100 0.743 Contact Map
4g1uA 2 0.447 100 0.746 Contact Map
2nq2A 2 0.4636 100 0.748 Contact Map
2m20A 2 0.0364 11.1 0.989 Contact Map
3ffvA 1 0.0909 6.4 0.99 Contact Map
2m67A 1 0.0742 6 0.99 Contact Map
2l9uA 2 0.0409 4.2 0.991 Contact Map
4cbkA 3 0.0667 4.2 0.991 Contact Map
1iijA 1 0.053 3.1 0.991 Contact Map
2kluA 1 0.0576 2.7 0.991 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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