GREMLIN Database
FHUA - Ferrichrome-iron receptor
UniProt: P06971 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG10302
Length: 747 (620)
Sequences: 53366 (44350)
Seq/√Len: 1781.1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
669_G689_T3.7491.00
621_Y645_H3.6611.00
223_Y254_W3.6281.00
486_Y507_K3.4791.00
484_G509_F3.4181.00
523_V558_V3.3891.00
575_N601_R3.3671.00
529_Y552_K3.3551.00
260_T321_H3.3161.00
531_E552_K3.1591.00
710_A742_T3.1451.00
664_T696_R3.0461.00
231_A246_Y3.0071.00
486_Y509_F2.9221.00
263_T318_S2.8041.00
405_H471_D2.8011.00
523_V560_Y2.6781.00
618_V650_W2.6661.00
229_G246_Y2.5741.00
260_T319_F2.5201.00
575_N599_R2.5101.00
478_V517_Y2.4451.00
410_G468_Y2.4261.00
268_F313_K2.4101.00
199_F209_T2.3781.00
477_K517_Y2.3641.00
88_A92_A2.3431.00
691_V717_F2.3281.00
567_I609_A2.3251.00
261_N320_D2.3151.00
599_R629_T2.2761.00
161_R185_V2.2691.00
259_K321_H2.2601.00
266_S313_K2.2241.00
713_V716_L2.2151.00
623_Y645_H2.1861.00
568_V608_K2.1761.00
669_G691_V2.1741.00
560_Y569_V2.1721.00
671_Y689_T2.1621.00
712_H740_V2.1431.00
696_R708_N2.0941.00
223_Y252_F2.0701.00
331_Q392_T2.0651.00
708_N744_T2.0621.00
666_G694_L2.0611.00
159_L184_M2.0571.00
570_T606_E2.0421.00
224_S253_T2.0401.00
667_T691_V2.0301.00
519_F525_P2.0291.00
215_D225_Y2.0221.00
87_T90_E1.9921.00
411_V465_T1.9871.00
326_T396_S1.9861.00
615_V651_A1.9691.00
329_V392_T1.9581.00
415_R463_K1.9481.00
257_D260_T1.9271.00
516_N524_T1.9111.00
333_L388_F1.9091.00
331_Q390_V1.9071.00
698_D708_N1.9001.00
531_E550_K1.8741.00
335_F388_F1.8691.00
674_S684_K1.8631.00
270_N311_N1.8591.00
413_F465_T1.8401.00
233_S244_Q1.8361.00
391_D412_D1.8351.00
707_S745_F1.8341.00
529_Y554_Y1.8151.00
478_V515_V1.8151.00
479_L518_L1.8031.00
266_S315_V1.7851.00
262_F319_F1.7831.00
488_W507_K1.7761.00
614_S653_Y1.7381.00
584_A592_S1.7351.00
198_Q210_G1.7301.00
195_K213_F1.7291.00
253_T261_N1.7201.00
327_F396_S1.7151.00
663_L697_Y1.7101.00
227_L250_P1.7071.00
519_F523_V1.6981.00
573_V601_R1.6951.00
585_D593_V1.6901.00
330_R393_Q1.6811.00
98_S101_E1.6781.00
616_N652_D1.6731.00
415_R461_K1.6701.00
581_N598_I1.6691.00
707_S743_A1.6691.00
320_D328_T1.6521.00
397_K406_T1.6511.00
230_L247_A1.6471.00
647_A671_Y1.6401.00
668_G692_D1.6371.00
191_T224_S1.6301.00
405_H473_A1.6291.00
320_D330_R1.6231.00
577_T597_E1.6161.00
552_K579_T1.6131.00
195_K199_F1.6091.00
615_V653_Y1.6031.00
160_E187_K1.5941.00
225_Y229_G1.5871.00
474_Q479_L1.5851.00
253_T263_T1.5841.00
139_L144_L1.5841.00
255_R261_N1.5821.00
577_T599_R1.5721.00
569_V607_A1.5711.00
559_K570_T1.5711.00
571_G605_I1.5691.00
566_P609_A1.5591.00
85_V163_E1.5581.00
198_Q744_T1.5511.00
225_Y252_F1.5481.00
553_Q576_L1.5481.00
520_D523_V1.5461.00
511_W531_E1.5401.00
711_L739_V1.5361.00
106_T164_I1.5341.00
713_V739_V1.5331.00
399_A404_D1.5281.00
671_Y687_S1.5071.00
329_V394_L1.5041.00
508_Q550_K1.5021.00
526_Y557_G1.5021.00
333_L390_V1.5021.00
140_N251_A1.5001.00
264_F315_V1.4961.00
617_V651_A1.4911.00
327_F394_L1.4701.00
334_R389_S1.4671.00
75_P78_K1.4631.00
403_I473_A1.4621.00
406_T472_Q1.4571.00
326_T398_F1.4521.00
196_E746_R1.4511.00
89_E93_L1.4471.00
163_E183_N1.4411.00
700_A706_G1.4391.00
664_T698_D1.4371.00
635_K639_P1.4371.00
699_L709_V1.4341.00
561_V568_V1.4321.00
511_W515_V1.4311.00
662_G697_Y1.4311.00
608_K618_V1.4221.00
567_I607_A1.4131.00
547_A580_N1.4121.00
693_A716_L1.4081.00
479_L516_N1.4071.00
88_A187_K1.4071.00
721_Y734_G1.4061.00
322_E328_T1.4051.00
139_L186_S1.4041.00
574_Y624_T1.3891.00
707_S711_L1.3891.00
713_V737_R1.3881.00
125_I180_G1.3881.00
525_P558_V1.3871.00
650_W668_G1.3861.00
561_V565_R1.3851.00
197_V209_T1.3841.00
652_D666_G1.3761.00
527_F554_Y1.3751.00
583_M595_G1.3741.00
526_Y559_K1.3741.00
550_K580_N1.3731.00
231_A244_Q1.3681.00
655_F661_S1.3581.00
466_G485_R1.3571.00
482_L513_G1.3431.00
466_G487_D1.3411.00
328_T395_Q1.3411.00
265_L316_G1.3371.00
90_E93_L1.3351.00
188_R253_T1.3341.00
601_R625_D1.3301.00
262_F317_Y1.3281.00
212_D226_R1.3241.00
155_D158_M1.3221.00
200_K208_Q1.3221.00
224_S255_R1.3191.00
26_G30_Y1.3191.00
480_V515_V1.3181.00
741_A745_F1.3131.00
709_V743_A1.3071.00
694_L710_A1.3061.00
406_T474_Q1.3041.00
160_E188_R1.3031.00
94_H105_Y1.2981.00
574_Y602_G1.2981.00
268_F311_N1.2971.00
514_G528_S1.2941.00
616_N654_T1.2921.00
523_V527_F1.2901.00
664_T708_N1.2891.00
227_L248_I1.2871.00
261_N322_E1.2851.00
404_D474_Q1.2801.00
645_H673_G1.2801.00
318_S330_R1.2801.00
663_L695_V1.2801.00
337_E386_Q1.2751.00
571_G603_V1.2701.00
619_G649_L1.2701.00
89_E92_A1.2651.00
323_F329_V1.2581.00
126_R604_E1.2581.00
665_L695_V1.2541.00
534_E549_S1.2541.00
108_G622_T1.2531.00
555_E572_A1.2531.00
708_N746_R1.2531.00
101_E104_S1.2531.00
617_V649_L1.2491.00
27_M30_Y1.2461.00
696_R710_A1.2421.00
188_R251_A1.2391.00
412_D466_G1.2371.00
701_R706_G1.2361.00
699_L707_S1.2361.00
140_N186_S1.2351.00
470_Q481_T1.2301.00
620_S648_S1.2261.00
670_R692_D1.2221.00
610_A616_N1.2201.00
197_V201_A1.2101.00
677_G682_S1.2081.00
630_T633_T1.2071.00
411_V467_V1.2061.00
472_Q481_T1.2061.00
554_Y577_T1.2041.00
324_N327_F1.2031.00
193_P197_V1.1941.00
714_N738_Q1.1901.00
259_K322_E1.1881.00
263_T320_D1.1851.00
554_Y575_N1.1841.00
200_K742_T1.1841.00
225_Y250_P1.1791.00
201_A207_F1.1791.00
692_D714_N1.1781.00
611_L617_V1.1751.00
672_T675_S1.1711.00
556_V573_V1.1691.00
667_T693_A1.1571.00
256_P262_F1.1561.00
196_E744_T1.1551.00
526_Y572_A1.1551.00
140_N265_L1.1551.00
487_D510_T1.1511.00
337_E384_K1.1491.00
229_G248_I1.1481.00
109_V125_I1.1471.00
142_L334_R1.1461.00
413_F463_K1.1441.00
569_V605_I1.1411.00
17_A20_V1.1401.00
518_L521_N1.1381.00
515_V519_F1.1371.00
332_N391_D1.1371.00
323_F394_L1.1351.00
654_T664_T1.1351.00
335_F386_Q1.1321.00
393_Q468_Y1.1311.00
608_K616_N1.1311.00
557_G572_A1.1301.00
573_V603_V1.1271.00
84_S166_R1.1251.00
711_L741_A1.1241.00
248_I268_F1.1221.00
226_R251_A1.1201.00
488_W505_D1.1131.00
138_Y143_K1.1111.00
126_R555_E1.1091.00
218_D223_Y1.1051.00
330_R395_Q1.1041.00
199_F207_F1.1001.00
264_F317_Y1.0961.00
228_T249_A1.0911.00
569_V573_V1.0911.00
61_I64_R1.0901.00
318_S332_N1.0891.00
160_E185_V1.0891.00
651_A667_T1.0891.00
107_P606_E1.0881.00
16_I19_V1.0821.00
110_S646_M1.0811.00
88_A160_E1.0811.00
622_T646_M1.0791.00
518_L524_T1.0791.00
652_D664_T1.0791.00
262_F266_S1.0791.00
196_E212_D1.0751.00
407_L471_D1.0701.00
270_N309_S1.0691.00
525_P556_V1.0681.00
477_K519_F1.0671.00
481_T514_G1.0671.00
465_T488_W1.0661.00
647_A673_G1.0581.00
551_G576_L1.0561.00
691_V716_L1.0551.00
472_Q479_L1.0481.00
603_V623_Y1.0451.00
700_A707_S1.0451.00
328_T397_K1.0401.00
193_P215_D1.0351.00
612_S615_V1.0341.00
193_P213_F1.0311.00
624_T628_Y1.0271.00
691_V719_R1.0271.00
532_S551_G1.0261.00
329_V333_L1.0251.00
404_D473_A1.0221.00
636_G639_P1.0221.00
579_T597_E1.0211.00
166_R604_E1.0201.00
676_Y684_K1.0191.00
106_T109_V1.0191.00
155_D230_L1.0181.00
19_V22_T1.0171.00
85_V161_R1.0171.00
467_V486_Y1.0121.00
267_Y314_M1.0051.00
178_P551_G1.0041.00
202_G206_L1.0011.00
527_F556_V0.9981.00
78_K518_L0.9981.00
207_F233_S0.9951.00
554_Y558_V0.9921.00
480_V513_G0.9911.00
264_F268_F0.9901.00
694_L712_H0.9881.00
522_G560_Y0.9831.00
695_V713_V0.9821.00
25_S28_S0.9761.00
462_Q491_Q0.9741.00
710_A744_T0.9741.00
194_L214_S0.9741.00
617_V628_Y0.9711.00
201_A205_S0.9701.00
672_T688_Y0.9671.00
256_P260_T0.9661.00
163_E185_V0.9661.00
489_A535_P0.9651.00
690_V721_Y0.9641.00
571_G575_N0.9611.00
670_R690_V0.9581.00
58_A61_I0.9471.00
18_V21_A0.9451.00
62_A65_Q0.9441.00
257_D321_H0.9431.00
209_T231_A0.9391.00
158_M228_T0.9381.00
475_W480_V0.9381.00
600_A626_A0.9361.00
251_A263_T0.9361.00
417_R459_L0.9361.00
136_N143_K0.9361.00
709_V741_A0.9341.00
638_T644_K0.9341.00
188_R263_T0.9311.00
558_V571_G0.9311.00
698_D746_R0.9301.00
510_T533_F0.9291.00
398_F407_L0.9251.00
655_F665_L0.9251.00
158_M249_A0.9231.00
242_E274_T0.9221.00
208_Q232_R0.9211.00
483_G512_R0.9191.00
551_G578_K0.9191.00
623_Y644_K0.9171.00
524_T559_K0.9171.00
313_K317_Y0.9141.00
255_R258_D0.9131.00
519_F558_V0.9131.00
158_M226_R0.9101.00
164_I182_L0.9101.00
80_P514_G0.9071.00
566_P610_A0.9061.00
714_N740_V0.9031.00
508_Q533_F0.9001.00
709_V713_V0.8991.00
80_P516_N0.8981.00
138_Y181_L0.8961.00
515_V527_F0.8961.00
706_G746_R0.8951.00
208_Q230_L0.8931.00
157_Y210_G0.8931.00
562_P569_V0.8921.00
610_A613_A0.8911.00
396_S407_L0.8911.00
190_T194_L0.8881.00
605_I609_A0.8871.00
621_Y647_A0.8851.00
138_Y183_N0.8851.00
597_E629_T0.8841.00
99_V184_M0.8821.00
511_W529_Y0.8811.00
716_L737_R0.8801.00
392_T396_S0.8761.00
467_V471_D0.8721.00
105_Y668_G0.8721.00
661_S697_Y0.8701.00
198_Q742_T0.8701.00
467_V488_W0.8681.00
91_M102_A0.8681.00
409_T469_V0.8671.00
211_F215_D0.8661.00
16_I20_V0.8661.00
25_S29_V0.8651.00
93_L652_D0.8641.00
473_A482_L0.8621.00
90_E105_Y0.8611.00
484_G511_W0.8611.00
142_L332_N0.8611.00
405_H410_G0.8601.00
137_N182_L0.8601.00
209_T213_F0.8581.00
609_A617_V0.8571.00
196_E199_F0.8571.00
614_S654_T0.8561.00
84_S106_T0.8541.00
603_V607_A0.8541.00
227_L231_A0.8541.00
191_T218_D0.8531.00
647_A651_A0.8521.00
690_V734_G0.8511.00
673_G687_S0.8501.00
312_E336_A0.8491.00
562_P567_I0.8491.00
674_S687_S0.8471.00
250_P254_W0.8451.00
549_S578_K0.8451.00
248_I252_F0.8441.00
210_G230_L0.8431.00
574_Y604_E0.8421.00
86_V106_T0.8411.00
205_S235_N0.8411.00
55_W58_A0.8341.00
96_P102_A0.8341.00
675_S685_V0.8341.00
396_S409_T0.8321.00
397_K404_D0.8321.00
399_A403_I0.8311.00
123_L137_N0.8301.00
689_T719_R0.8281.00
214_S226_R0.8281.00
190_T214_S0.8271.00
84_S606_E0.8271.00
74_T79_V0.8271.00
272_P309_S0.8261.00
395_Q406_T0.8251.00
26_G29_V0.8241.00
171_V483_G0.8221.00
481_T516_N0.8211.00
256_P319_F0.8211.00
88_A91_M0.8211.00
189_P224_S0.8191.00
513_G529_Y0.8181.00
567_I571_G0.8171.00
665_L693_A0.8161.00
108_G166_R0.8151.00
21_A24_V0.8151.00
246_Y250_P0.8151.00
390_V394_L0.8141.00
93_L664_T0.8141.00
574_Y622_T0.8141.00
79_V83_I0.8121.00
22_T25_S0.8121.00
83_I163_E0.8111.00
20_V23_A0.8111.00
718_D736_E0.8101.00
464_Q535_P0.8101.00
107_P620_S0.8091.00
409_T413_F0.8081.00
193_P216_S0.8061.00
654_T698_D0.8051.00
123_L182_L0.8031.00
390_V413_F0.8031.00
223_Y227_L0.7981.00
74_T78_K0.7971.00
552_K577_T0.7941.00
662_G698_D0.7941.00
143_K176_S0.7931.00
315_V335_F0.7921.00
578_K581_N0.7921.00
611_L651_A0.7911.00
654_T662_G0.7911.00
61_I67_A0.7911.00
645_H671_Y0.7901.00
111_V123_L0.7891.00
173_Y181_L0.7861.00
17_A21_A0.7861.00
407_L411_V0.7861.00
393_Q408_L0.7851.00
650_W666_G0.7831.00
162_A184_M0.7811.00
647_A689_T0.7791.00
246_Y270_N0.7791.00
684_K723_A0.7791.00
675_S686_G0.7781.00
706_G745_F0.7781.00
469_V484_G0.7751.00
60_T65_Q0.7741.00
617_V624_T0.7731.00
556_V560_Y0.7731.00
212_D228_T0.7721.00
392_T411_V0.7711.00
233_S242_E0.7691.00
625_D644_K0.7691.00
550_K579_T0.7671.00
232_R245_R0.7661.00
598_I639_P0.7651.00
698_D706_G0.7651.00
634_Y637_N0.7641.00
617_V621_Y0.7641.00
343_N380_V0.7641.00
624_T642_V0.7641.00
618_V652_D0.7611.00
60_T63_A0.7601.00
619_G647_A0.7571.00
326_T397_K0.7561.00
97_K101_E0.7561.00
419_D459_L0.7541.00
104_S670_R0.7531.00
644_K673_G0.7531.00
417_R461_K0.7531.00
664_T667_T0.7521.00
141_G183_N0.7511.00
693_A713_V0.7511.00
387_N416_M0.7511.00
62_A67_A0.7511.00
388_F392_T0.7501.00
22_T26_G0.7491.00
614_S655_F0.7491.00
216_S224_S0.7481.00
74_T472_Q0.7471.00
510_T531_E0.7471.00
718_D737_R0.7461.00
323_F327_F0.7451.00
614_S617_V0.7431.00
193_P199_F0.7411.00
408_L470_Q0.7391.00
124_I129_A0.7371.00
313_K337_E0.7361.00
24_V27_M0.7361.00
407_L469_V0.7351.00
147_N151_D0.7341.00
19_V23_A0.7341.00
61_I65_Q0.7341.00
480_V484_G0.7341.00
62_A66_S0.7331.00
325_D398_F0.7301.00
676_Y685_V0.7291.00
99_V102_A0.7291.00
197_V211_F0.7281.00
24_V28_S0.7281.00
125_I164_I0.7281.00
224_S261_N0.7261.00
30_Y33_A0.7261.00
272_P307_T0.7251.00
82_S555_E0.7251.00
191_T255_R0.7241.00
249_A267_Y0.7241.00
147_N152_A0.7241.00
549_S581_N0.7221.00
387_N414_M0.7211.00
568_V610_A0.7201.00
189_P253_T0.7201.00
187_K212_D0.7191.00
617_V620_S0.7191.00
565_R569_V0.7181.00
271_E310_R0.7171.00
192_E195_K0.7121.00
156_P159_L0.7111.00
412_D468_Y0.7091.00
617_V622_T0.7091.00
708_N711_L0.7091.00
489_A506_D0.7081.00
470_Q512_R0.7071.00
607_A619_G0.7071.00
201_A209_T0.7061.00
578_K598_I0.7061.00
84_S107_P0.7051.00
622_T628_Y0.7041.00
172_L408_L0.7031.00
17_A24_V0.7031.00
686_G719_R0.7031.00
126_R574_Y0.7021.00
520_D560_Y0.6991.00
609_A612_S0.6981.00
653_Y665_L0.6981.00
735_A738_Q0.6971.00
405_H409_T0.6971.00
717_F720_E0.6961.00
206_L234_A0.6951.00
655_F662_G0.6951.00
577_T629_T0.6941.00
508_Q531_E0.6941.00
147_N150_N0.6941.00
389_S414_M0.6931.00
475_W515_V0.6921.00
157_Y198_Q0.6921.00
20_V24_V0.6921.00
226_R249_A0.6921.00
32_Q36_E0.6901.00
403_I410_G0.6891.00
251_A265_L0.6881.00
506_D548_P0.6881.00
576_L600_A0.6871.00
479_L482_L0.6871.00
697_Y700_A0.6871.00
254_W257_D0.6851.00
142_L316_G0.6841.00
165_M173_Y0.6841.00
260_T264_F0.6831.00
471_D482_L0.6831.00
712_H742_T0.6821.00
537_S546_F0.6821.00
82_S572_A0.6791.00
327_F409_T0.6781.00
176_S464_Q0.6771.00
342_Q381_D0.6771.00
319_F331_Q0.6771.00
482_L486_Y0.6761.00
616_N619_G0.6761.00
339_K384_K0.6761.00
512_R528_S0.6751.00
126_R602_G0.6731.00
18_V22_T0.6721.00
624_T646_M0.6711.00
607_A611_L0.6701.00
463_K490_D0.6701.00
316_G334_R0.6691.00
92_A744_T0.6691.00
416_M462_Q0.6691.00
193_P225_Y0.6681.00
76_I85_V0.6681.00
634_Y639_P0.6671.00
513_G517_Y0.6661.00
165_M181_L0.6661.00
21_A25_S0.6651.00
462_Q535_P0.6641.00
741_A744_T0.6621.00
223_Y256_P0.6621.00
194_L746_R0.6611.00
332_N393_Q0.6601.00
202_G205_S0.6601.00
408_L472_Q0.6591.00
188_R265_L0.6591.00
739_V743_A0.6581.00
322_E325_D0.6581.00
200_K740_V0.6581.00
582_L592_S0.6571.00
638_T676_Y0.6551.00
110_S643_P0.6551.00
651_A655_F0.6541.00
166_R606_E0.6531.00
665_L669_G0.6531.00
327_F407_L0.6501.00
536_S539_V0.6501.00
109_V123_L0.6491.00
606_E618_V0.6491.00
606_E620_S0.6461.00
646_M672_T0.6461.00
203_T739_V0.6461.00
217_L225_Y0.6451.00
137_N184_M0.6451.00
68_T71_K0.6441.00
197_V745_F0.6431.00
195_K211_F0.6431.00
599_R627_E0.6431.00
168_P530_S0.6421.00
475_W478_V0.6421.00
77_Q561_V0.6411.00
136_N177_S0.6411.00
30_Y34_A0.6401.00
233_S246_Y0.6391.00
546_F582_L0.6381.00
464_Q489_A0.6361.00
33_A36_E0.6351.00
321_H324_N0.6331.00
217_L223_Y0.6331.00
90_E94_H0.6331.00
237_Q240_G0.6311.00
562_P565_R0.6301.00
197_V200_K0.6301.00
259_K323_F0.6301.00
568_V571_G0.6301.00
263_T330_R0.6271.00
191_T216_S0.6271.00
388_F415_R0.6261.00
63_A66_S0.6251.00
315_V319_F0.6251.00
23_A26_G0.6241.00
398_F405_H0.6221.00
743_A747_F0.6221.00
508_Q548_P0.6201.00
414_M464_Q0.6201.00
253_T256_P0.6191.00
511_W514_G0.6191.00
477_K521_N0.6181.00
188_R261_N0.6181.00
625_D628_Y0.6171.00
699_L706_G0.6171.00
615_V619_G0.6171.00
649_L689_T0.6151.00
60_T64_R0.6151.00
477_K518_L0.6151.00
160_E190_T0.6151.00
143_K389_S0.6141.00
663_L667_T0.6141.00
560_Y564_D0.6141.00
135_Q179_G0.6121.00
70_T74_T0.6111.00
211_F229_G0.6101.00
637_N676_Y0.6091.00
394_L409_T0.6061.00
16_I23_A0.6061.00
244_Q272_P0.6061.00
319_F323_F0.6051.00
644_K674_S0.6041.00
136_N181_L0.6041.00
102_A156_P0.6031.00
585_D591_F0.6031.00
655_F663_L0.6011.00
600_A624_T0.6001.00
627_E636_G0.6001.00
403_I412_D0.6001.00
477_K522_G0.5991.00
128_F179_G0.5991.00
101_E714_N0.5991.00
331_Q335_F0.5991.00
691_V713_V0.5981.00
193_P196_E0.5981.00
168_P532_S0.5971.00
470_Q483_G0.5951.00
341_S382_D0.5941.00
223_Y250_P0.5941.00
80_P481_T0.5941.00
93_L654_T0.5941.00
165_M169_V0.5941.00
689_T717_F0.5931.00
317_Y321_H0.5931.00
566_P611_L0.5911.00
200_K710_A0.5901.00
582_L594_E0.5901.00
528_S555_E0.5901.00
155_D210_G0.5901.00
198_Q201_A0.5891.00
386_Q417_R0.5891.00
669_G717_F0.5881.00
70_T73_D0.5871.00
403_I407_L0.5861.00
518_L522_G0.5851.00
341_S380_V0.5851.00
558_V569_V0.5851.00
144_L314_M0.5841.00
204_D738_Q0.5831.00
673_G689_T0.5831.00
420_I458_I0.5831.00
394_L397_K0.5821.00
316_G332_N0.5811.00
526_Y570_T0.5801.00
564_D567_I0.5801.00
604_E622_T0.5791.00
473_A480_V0.5771.00
517_Y522_G0.5771.00
640_A676_Y0.5761.00
112_G122_H0.5751.00
406_T409_T0.5741.00
99_V159_L0.5741.00
243_E271_E0.5721.00
157_Y228_T0.5721.00
562_P566_P0.5721.00
403_I408_L0.5711.00
96_P101_E0.5711.00
695_V699_L0.5711.00
626_A642_V0.5701.00
128_F132_G0.5681.00
405_H408_L0.5681.00
128_F578_K0.5681.00
646_M670_R0.5671.00
626_A639_P0.5661.00
185_V188_R0.5661.00
206_L232_R0.5661.00
82_S166_R0.5661.00
77_Q518_L0.5621.00
189_P226_R0.5611.00
213_F216_S0.5601.00
265_L318_S0.5591.00
57_P60_T0.5591.00
649_L669_G0.5581.00
146_G151_D0.5581.00
519_F522_G0.5581.00
701_R707_S0.5571.00
385_L418_N0.5561.00
322_E326_T0.5561.00
394_L398_F0.5561.00
547_A550_K0.5561.00
102_A106_T0.5561.00
203_T206_L0.5561.00
23_A27_M0.5561.00
651_A669_G0.5561.00
167_G555_E0.5551.00
398_F403_I0.5551.00
236_A241_S0.5531.00
533_F550_K0.5531.00
157_Y196_E0.5521.00
171_V470_Q0.5521.00
128_F600_A0.5511.00
250_P253_T0.5501.00
422_A456_Y0.5501.00
691_V695_V0.5501.00
158_M247_A0.5491.00
331_Q388_F0.5491.00
513_G516_N0.5491.00
321_H329_V0.5481.00
32_Q35_V0.5481.00
447_A450_P0.5481.00
474_Q518_L0.5471.00
193_P201_A0.5461.00
610_A614_S0.5461.00
58_A62_A0.5461.00
648_S668_G0.5441.00
554_Y573_V0.5441.00
614_S628_Y0.5441.00
465_T490_D0.5431.00
178_P532_S0.5421.00
107_P166_R0.5411.00
18_V25_S0.5411.00
619_G623_Y0.5401.00
237_Q736_E0.5401.00
517_Y520_D0.5401.00
643_P672_T0.5401.00
640_A644_K0.5401.00
648_S670_R0.5391.00
662_G699_L0.5391.00
643_P675_S0.5381.00
662_G700_A0.5381.00
635_K638_T0.5381.00
190_T224_S0.5371.00
512_R530_S0.5361.00
617_V623_Y0.5361.00
611_L614_S0.5351.00
76_I83_I0.5351.00
155_D208_Q0.5351.00
541_K591_F0.5341.00
90_E618_V0.5341.00
77_Q524_T0.5341.00
667_T716_L0.5331.00
56_G59_A0.5321.00
256_P259_K0.5311.00
138_Y173_Y0.5301.00
81_Q512_R0.5301.00
405_H412_D0.5291.00
245_R271_E0.5281.00
213_F225_Y0.5281.00
693_A711_L0.5281.00
329_V390_V0.5271.00
107_P110_S0.5271.00
698_D701_R0.5261.00
462_Q489_A0.5261.00
250_P266_S0.5261.00
490_D505_D0.5261.00
532_S553_Q0.5261.00
110_S672_T0.5251.00
34_A37_P0.5251.00
615_V628_Y0.5241.00
16_I24_V0.5231.00
327_F331_Q0.5231.00
192_E216_S0.5221.00
80_P83_I0.5211.00
306_N342_Q0.5211.00
105_Y650_W0.5201.00
249_A265_L0.5201.00
311_N339_K0.5201.00
16_I22_T0.5191.00
408_L412_D0.5181.00
611_L615_V0.5171.00
36_E55_W0.5171.00
125_I135_Q0.5171.00
172_L468_Y0.5151.00
695_V711_L0.5151.00
78_K474_Q0.5151.00
115_G118_N0.5151.00
468_Y485_R0.5151.00
336_A387_N0.5141.00
581_N596_G0.5141.00
605_I621_Y0.5141.00
259_K324_N0.5131.00
405_H474_Q0.5121.00
581_N600_A0.5121.00
694_L708_N0.5091.00
178_P534_E0.5081.00
389_S412_D0.5081.00
566_P612_S0.5081.00
504_R547_A0.5071.00
625_D638_T0.5071.00
557_G570_T0.5071.00
252_F264_F0.5061.00
207_F231_A0.5051.00
578_K600_A0.5051.00
103_L109_V0.5051.00
523_V562_P0.5041.00
195_K747_F0.5041.00
699_L743_A0.5041.00
270_N313_K0.5041.00
382_D421_N0.5041.00
104_S692_D0.5031.00
651_A665_L0.5021.00
317_Y333_L0.5021.00
384_K419_D0.5021.00
533_F548_P0.5011.00
513_G527_F0.5011.00
618_V666_G0.5011.00
104_S111_V0.5011.00
465_T469_V0.5011.00
144_L336_A0.5011.00
549_S580_N0.5001.00
28_S31_A0.5001.00
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3qlbA 1 0.8929 100 0.249 Contact Map
4cu4A 1 0.925 100 0.255 Contact Map
3efmA 1 0.7497 100 0.262 Contact Map
1kmoA 1 0.83 100 0.267 Contact Map
1xkwA 1 0.8608 100 0.272 Contact Map
2w16A 1 0.9317 100 0.273 Contact Map
2gufA 1 0.7202 100 0.318 Contact Map
3v8xA 1 0.8594 100 0.318 Contact Map
2hdiA 1 0.7242 100 0.324 Contact Map
3cslA 1 0.8046 100 0.332 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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