FHUA - ECOLI - GREMLIN Contacts

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FHUA - Ferrichrome-iron receptor

UniProt:	P06971	Sequences: MARSKTAQPKHSLRKIAVVVATAVSGMSVYAQAAVEPKEDTITVTAAPAPQESAWGPAATIAARQSATGTKTDTPIQKVPQSISVVTAEEMALHQPKSVKEALSYTPGVSVGTRGASNTYDHLIIRGFAAEGQSQNNYLNGLKLQGNFYNDAVIDPYMLERAEIMRGPVSVLYGKSSPGGLLNMVSKRPTTEPLKEVQFKAGTDSLFQTGFDFSDSLDDDGVYSYRLTGLARSANAQQKGSEEQRYAIAPAFTWRPDDKTNFTFLSYFQNEPETGYYGWLPKEGTVEPLPNGKRLPTDFNEGAKNNTYSRNEKMVGYSFDHEFNDTFTVRQNLRFAENKTSQNSVYGYGVCSDPANAYSKQCAALAPADKGHYLARKYVVDDEKLQNFSVDTQLQSKFATGDIDHTLLTGVDFMRMRNDINAWFGYDDSVPLLNLYNPVNTDFDFNAKDPANSGPYRILNKQKQTGVYVQDQAQWDKVLVTLGGRYDWADQESLNRVAGTTDKRDDKQFTWRGGVNYLFDNGVTPYFSYSESFEPSSQVGKDGNIFAPSKGKQYEVGVKYVPEDRPIVVTGAVYNLTKTNNLMADPEGSFFSVEGGEIRARGVEIEAKAALSASVNVVGSYTYTDAEYTTDTTYKGNTPAQVPKHMASLWADYTFFDGPLSGLTLGTGGRYTGSSYGDPANSFKVGSYTVVDALVRYDLARVGMAGSNVALHVNNLFDREYVASCFNTYGCFWGAERQVVATATFRF	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10302
Length:	747 (620)
Sequences:	53366 (44350)
Seq/√Len:	1781.1

ECOLI - FHUA FHUE FIU FECA FEPA CIRA YNCD YDDB BTUB

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
669_G	689_T	3.749	1.00
621_Y	645_H	3.661	1.00
223_Y	254_W	3.628	1.00
486_Y	507_K	3.479	1.00
484_G	509_F	3.418	1.00
523_V	558_V	3.389	1.00
575_N	601_R	3.367	1.00
529_Y	552_K	3.355	1.00
260_T	321_H	3.316	1.00
531_E	552_K	3.159	1.00
710_A	742_T	3.145	1.00
664_T	696_R	3.046	1.00
231_A	246_Y	3.007	1.00
486_Y	509_F	2.922	1.00
263_T	318_S	2.804	1.00
405_H	471_D	2.801	1.00
523_V	560_Y	2.678	1.00
618_V	650_W	2.666	1.00
229_G	246_Y	2.574	1.00
260_T	319_F	2.520	1.00
575_N	599_R	2.510	1.00
478_V	517_Y	2.445	1.00
410_G	468_Y	2.426	1.00
268_F	313_K	2.410	1.00
199_F	209_T	2.378	1.00
477_K	517_Y	2.364	1.00
88_A	92_A	2.343	1.00
691_V	717_F	2.328	1.00
567_I	609_A	2.325	1.00
261_N	320_D	2.315	1.00
599_R	629_T	2.276	1.00
161_R	185_V	2.269	1.00
259_K	321_H	2.260	1.00
266_S	313_K	2.224	1.00
713_V	716_L	2.215	1.00
623_Y	645_H	2.186	1.00
568_V	608_K	2.176	1.00
669_G	691_V	2.174	1.00
560_Y	569_V	2.172	1.00
671_Y	689_T	2.162	1.00
712_H	740_V	2.143	1.00
696_R	708_N	2.094	1.00
223_Y	252_F	2.070	1.00
331_Q	392_T	2.065	1.00
708_N	744_T	2.062	1.00
666_G	694_L	2.061	1.00
159_L	184_M	2.057	1.00
570_T	606_E	2.042	1.00
224_S	253_T	2.040	1.00
667_T	691_V	2.030	1.00
519_F	525_P	2.029	1.00
215_D	225_Y	2.022	1.00
87_T	90_E	1.992	1.00
411_V	465_T	1.987	1.00
326_T	396_S	1.986	1.00
615_V	651_A	1.969	1.00
329_V	392_T	1.958	1.00
415_R	463_K	1.948	1.00
257_D	260_T	1.927	1.00
516_N	524_T	1.911	1.00
333_L	388_F	1.909	1.00
331_Q	390_V	1.907	1.00
698_D	708_N	1.900	1.00
531_E	550_K	1.874	1.00
335_F	388_F	1.869	1.00
674_S	684_K	1.863	1.00
270_N	311_N	1.859	1.00
413_F	465_T	1.840	1.00
233_S	244_Q	1.836	1.00
391_D	412_D	1.835	1.00
707_S	745_F	1.834	1.00
529_Y	554_Y	1.815	1.00
478_V	515_V	1.815	1.00
479_L	518_L	1.803	1.00
266_S	315_V	1.785	1.00
262_F	319_F	1.783	1.00
488_W	507_K	1.776	1.00
614_S	653_Y	1.738	1.00
584_A	592_S	1.735	1.00
198_Q	210_G	1.730	1.00
195_K	213_F	1.729	1.00
253_T	261_N	1.720	1.00
327_F	396_S	1.715	1.00
663_L	697_Y	1.710	1.00
227_L	250_P	1.707	1.00
519_F	523_V	1.698	1.00
573_V	601_R	1.695	1.00
585_D	593_V	1.690	1.00
330_R	393_Q	1.681	1.00
98_S	101_E	1.678	1.00
616_N	652_D	1.673	1.00
415_R	461_K	1.670	1.00
581_N	598_I	1.669	1.00
707_S	743_A	1.669	1.00
320_D	328_T	1.652	1.00
397_K	406_T	1.651	1.00
230_L	247_A	1.647	1.00
647_A	671_Y	1.640	1.00
668_G	692_D	1.637	1.00
191_T	224_S	1.630	1.00
405_H	473_A	1.629	1.00
320_D	330_R	1.623	1.00
577_T	597_E	1.616	1.00
552_K	579_T	1.613	1.00
195_K	199_F	1.609	1.00
615_V	653_Y	1.603	1.00
160_E	187_K	1.594	1.00
225_Y	229_G	1.587	1.00
474_Q	479_L	1.585	1.00
253_T	263_T	1.584	1.00
139_L	144_L	1.584	1.00
255_R	261_N	1.582	1.00
577_T	599_R	1.572	1.00
569_V	607_A	1.571	1.00
559_K	570_T	1.571	1.00
571_G	605_I	1.569	1.00
566_P	609_A	1.559	1.00
85_V	163_E	1.558	1.00
198_Q	744_T	1.551	1.00
225_Y	252_F	1.548	1.00
553_Q	576_L	1.548	1.00
520_D	523_V	1.546	1.00
511_W	531_E	1.540	1.00
711_L	739_V	1.536	1.00
106_T	164_I	1.534	1.00
713_V	739_V	1.533	1.00
399_A	404_D	1.528	1.00
671_Y	687_S	1.507	1.00
329_V	394_L	1.504	1.00
508_Q	550_K	1.502	1.00
526_Y	557_G	1.502	1.00
333_L	390_V	1.502	1.00
140_N	251_A	1.500	1.00
264_F	315_V	1.496	1.00
617_V	651_A	1.491	1.00
327_F	394_L	1.470	1.00
334_R	389_S	1.467	1.00
75_P	78_K	1.463	1.00
403_I	473_A	1.462	1.00
406_T	472_Q	1.457	1.00
326_T	398_F	1.452	1.00
196_E	746_R	1.451	1.00
89_E	93_L	1.447	1.00
163_E	183_N	1.441	1.00
700_A	706_G	1.439	1.00
664_T	698_D	1.437	1.00
635_K	639_P	1.437	1.00
699_L	709_V	1.434	1.00
561_V	568_V	1.432	1.00
511_W	515_V	1.431	1.00
662_G	697_Y	1.431	1.00
608_K	618_V	1.422	1.00
567_I	607_A	1.413	1.00
547_A	580_N	1.412	1.00
693_A	716_L	1.408	1.00
479_L	516_N	1.407	1.00
88_A	187_K	1.407	1.00
721_Y	734_G	1.406	1.00
322_E	328_T	1.405	1.00
139_L	186_S	1.404	1.00
574_Y	624_T	1.389	1.00
707_S	711_L	1.389	1.00
713_V	737_R	1.388	1.00
125_I	180_G	1.388	1.00
525_P	558_V	1.387	1.00
650_W	668_G	1.386	1.00
561_V	565_R	1.385	1.00
197_V	209_T	1.384	1.00
652_D	666_G	1.376	1.00
527_F	554_Y	1.375	1.00
583_M	595_G	1.374	1.00
526_Y	559_K	1.374	1.00
550_K	580_N	1.373	1.00
231_A	244_Q	1.368	1.00
655_F	661_S	1.358	1.00
466_G	485_R	1.357	1.00
482_L	513_G	1.343	1.00
466_G	487_D	1.341	1.00
328_T	395_Q	1.341	1.00
265_L	316_G	1.337	1.00
90_E	93_L	1.335	1.00
188_R	253_T	1.334	1.00
601_R	625_D	1.330	1.00
262_F	317_Y	1.328	1.00
212_D	226_R	1.324	1.00
155_D	158_M	1.322	1.00
200_K	208_Q	1.322	1.00
224_S	255_R	1.319	1.00
26_G	30_Y	1.319	1.00
480_V	515_V	1.318	1.00
741_A	745_F	1.313	1.00
709_V	743_A	1.307	1.00
694_L	710_A	1.306	1.00
406_T	474_Q	1.304	1.00
160_E	188_R	1.303	1.00
94_H	105_Y	1.298	1.00
574_Y	602_G	1.298	1.00
268_F	311_N	1.297	1.00
514_G	528_S	1.294	1.00
616_N	654_T	1.292	1.00
523_V	527_F	1.290	1.00
664_T	708_N	1.289	1.00
227_L	248_I	1.287	1.00
261_N	322_E	1.285	1.00
404_D	474_Q	1.280	1.00
645_H	673_G	1.280	1.00
318_S	330_R	1.280	1.00
663_L	695_V	1.280	1.00
337_E	386_Q	1.275	1.00
571_G	603_V	1.270	1.00
619_G	649_L	1.270	1.00
89_E	92_A	1.265	1.00
323_F	329_V	1.258	1.00
126_R	604_E	1.258	1.00
665_L	695_V	1.254	1.00
534_E	549_S	1.254	1.00
108_G	622_T	1.253	1.00
555_E	572_A	1.253	1.00
708_N	746_R	1.253	1.00
101_E	104_S	1.253	1.00
617_V	649_L	1.249	1.00
27_M	30_Y	1.246	1.00
696_R	710_A	1.242	1.00
188_R	251_A	1.239	1.00
412_D	466_G	1.237	1.00
701_R	706_G	1.236	1.00
699_L	707_S	1.236	1.00
140_N	186_S	1.235	1.00
470_Q	481_T	1.230	1.00
620_S	648_S	1.226	1.00
670_R	692_D	1.222	1.00
610_A	616_N	1.220	1.00
197_V	201_A	1.210	1.00
677_G	682_S	1.208	1.00
630_T	633_T	1.207	1.00
411_V	467_V	1.206	1.00
472_Q	481_T	1.206	1.00
554_Y	577_T	1.204	1.00
324_N	327_F	1.203	1.00
193_P	197_V	1.194	1.00
714_N	738_Q	1.190	1.00
259_K	322_E	1.188	1.00
263_T	320_D	1.185	1.00
554_Y	575_N	1.184	1.00
200_K	742_T	1.184	1.00
225_Y	250_P	1.179	1.00
201_A	207_F	1.179	1.00
692_D	714_N	1.178	1.00
611_L	617_V	1.175	1.00
672_T	675_S	1.171	1.00
556_V	573_V	1.169	1.00
667_T	693_A	1.157	1.00
256_P	262_F	1.156	1.00
196_E	744_T	1.155	1.00
526_Y	572_A	1.155	1.00
140_N	265_L	1.155	1.00
487_D	510_T	1.151	1.00
337_E	384_K	1.149	1.00
229_G	248_I	1.148	1.00
109_V	125_I	1.147	1.00
142_L	334_R	1.146	1.00
413_F	463_K	1.144	1.00
569_V	605_I	1.141	1.00
17_A	20_V	1.140	1.00
518_L	521_N	1.138	1.00
515_V	519_F	1.137	1.00
332_N	391_D	1.137	1.00
323_F	394_L	1.135	1.00
654_T	664_T	1.135	1.00
335_F	386_Q	1.132	1.00
393_Q	468_Y	1.131	1.00
608_K	616_N	1.131	1.00
557_G	572_A	1.130	1.00
573_V	603_V	1.127	1.00
84_S	166_R	1.125	1.00
711_L	741_A	1.124	1.00
248_I	268_F	1.122	1.00
226_R	251_A	1.120	1.00
488_W	505_D	1.113	1.00
138_Y	143_K	1.111	1.00
126_R	555_E	1.109	1.00
218_D	223_Y	1.105	1.00
330_R	395_Q	1.104	1.00
199_F	207_F	1.100	1.00
264_F	317_Y	1.096	1.00
228_T	249_A	1.091	1.00
569_V	573_V	1.091	1.00
61_I	64_R	1.090	1.00
318_S	332_N	1.089	1.00
160_E	185_V	1.089	1.00
651_A	667_T	1.089	1.00
107_P	606_E	1.088	1.00
16_I	19_V	1.082	1.00
110_S	646_M	1.081	1.00
88_A	160_E	1.081	1.00
622_T	646_M	1.079	1.00
518_L	524_T	1.079	1.00
652_D	664_T	1.079	1.00
262_F	266_S	1.079	1.00
196_E	212_D	1.075	1.00
407_L	471_D	1.070	1.00
270_N	309_S	1.069	1.00
525_P	556_V	1.068	1.00
477_K	519_F	1.067	1.00
481_T	514_G	1.067	1.00
465_T	488_W	1.066	1.00
647_A	673_G	1.058	1.00
551_G	576_L	1.056	1.00
691_V	716_L	1.055	1.00
472_Q	479_L	1.048	1.00
603_V	623_Y	1.045	1.00
700_A	707_S	1.045	1.00
328_T	397_K	1.040	1.00
193_P	215_D	1.035	1.00
612_S	615_V	1.034	1.00
193_P	213_F	1.031	1.00
624_T	628_Y	1.027	1.00
691_V	719_R	1.027	1.00
532_S	551_G	1.026	1.00
329_V	333_L	1.025	1.00
404_D	473_A	1.022	1.00
636_G	639_P	1.022	1.00
579_T	597_E	1.021	1.00
166_R	604_E	1.020	1.00
676_Y	684_K	1.019	1.00
106_T	109_V	1.019	1.00
155_D	230_L	1.018	1.00
19_V	22_T	1.017	1.00
85_V	161_R	1.017	1.00
467_V	486_Y	1.012	1.00
267_Y	314_M	1.005	1.00
178_P	551_G	1.004	1.00
202_G	206_L	1.001	1.00
527_F	556_V	0.998	1.00
78_K	518_L	0.998	1.00
207_F	233_S	0.995	1.00
554_Y	558_V	0.992	1.00
480_V	513_G	0.991	1.00
264_F	268_F	0.990	1.00
694_L	712_H	0.988	1.00
522_G	560_Y	0.983	1.00
695_V	713_V	0.982	1.00
25_S	28_S	0.976	1.00
462_Q	491_Q	0.974	1.00
710_A	744_T	0.974	1.00
194_L	214_S	0.974	1.00
617_V	628_Y	0.971	1.00
201_A	205_S	0.970	1.00
672_T	688_Y	0.967	1.00
256_P	260_T	0.966	1.00
163_E	185_V	0.966	1.00
489_A	535_P	0.965	1.00
690_V	721_Y	0.964	1.00
571_G	575_N	0.961	1.00
670_R	690_V	0.958	1.00
58_A	61_I	0.947	1.00
18_V	21_A	0.945	1.00
62_A	65_Q	0.944	1.00
257_D	321_H	0.943	1.00
209_T	231_A	0.939	1.00
158_M	228_T	0.938	1.00
475_W	480_V	0.938	1.00
600_A	626_A	0.936	1.00
251_A	263_T	0.936	1.00
417_R	459_L	0.936	1.00
136_N	143_K	0.936	1.00
709_V	741_A	0.934	1.00
638_T	644_K	0.934	1.00
188_R	263_T	0.931	1.00
558_V	571_G	0.931	1.00
698_D	746_R	0.930	1.00
510_T	533_F	0.929	1.00
398_F	407_L	0.925	1.00
655_F	665_L	0.925	1.00
158_M	249_A	0.923	1.00
242_E	274_T	0.922	1.00
208_Q	232_R	0.921	1.00
483_G	512_R	0.919	1.00
551_G	578_K	0.919	1.00
623_Y	644_K	0.917	1.00
524_T	559_K	0.917	1.00
313_K	317_Y	0.914	1.00
255_R	258_D	0.913	1.00
519_F	558_V	0.913	1.00
158_M	226_R	0.910	1.00
164_I	182_L	0.910	1.00
80_P	514_G	0.907	1.00
566_P	610_A	0.906	1.00
714_N	740_V	0.903	1.00
508_Q	533_F	0.900	1.00
709_V	713_V	0.899	1.00
80_P	516_N	0.898	1.00
138_Y	181_L	0.896	1.00
515_V	527_F	0.896	1.00
706_G	746_R	0.895	1.00
208_Q	230_L	0.893	1.00
157_Y	210_G	0.893	1.00
562_P	569_V	0.892	1.00
610_A	613_A	0.891	1.00
396_S	407_L	0.891	1.00
190_T	194_L	0.888	1.00
605_I	609_A	0.887	1.00
621_Y	647_A	0.885	1.00
138_Y	183_N	0.885	1.00
597_E	629_T	0.884	1.00
99_V	184_M	0.882	1.00
511_W	529_Y	0.881	1.00
716_L	737_R	0.880	1.00
392_T	396_S	0.876	1.00
467_V	471_D	0.872	1.00
105_Y	668_G	0.872	1.00
661_S	697_Y	0.870	1.00
198_Q	742_T	0.870	1.00
467_V	488_W	0.868	1.00
91_M	102_A	0.868	1.00
409_T	469_V	0.867	1.00
211_F	215_D	0.866	1.00
16_I	20_V	0.866	1.00
25_S	29_V	0.865	1.00
93_L	652_D	0.864	1.00
473_A	482_L	0.862	1.00
90_E	105_Y	0.861	1.00
484_G	511_W	0.861	1.00
142_L	332_N	0.861	1.00
405_H	410_G	0.860	1.00
137_N	182_L	0.860	1.00
209_T	213_F	0.858	1.00
609_A	617_V	0.857	1.00
196_E	199_F	0.857	1.00
614_S	654_T	0.856	1.00
84_S	106_T	0.854	1.00
603_V	607_A	0.854	1.00
227_L	231_A	0.854	1.00
191_T	218_D	0.853	1.00
647_A	651_A	0.852	1.00
690_V	734_G	0.851	1.00
673_G	687_S	0.850	1.00
312_E	336_A	0.849	1.00
562_P	567_I	0.849	1.00
674_S	687_S	0.847	1.00
250_P	254_W	0.845	1.00
549_S	578_K	0.845	1.00
248_I	252_F	0.844	1.00
210_G	230_L	0.843	1.00
574_Y	604_E	0.842	1.00
86_V	106_T	0.841	1.00
205_S	235_N	0.841	1.00
55_W	58_A	0.834	1.00
96_P	102_A	0.834	1.00
675_S	685_V	0.834	1.00
396_S	409_T	0.832	1.00
397_K	404_D	0.832	1.00
399_A	403_I	0.831	1.00
123_L	137_N	0.830	1.00
689_T	719_R	0.828	1.00
214_S	226_R	0.828	1.00
190_T	214_S	0.827	1.00
84_S	606_E	0.827	1.00
74_T	79_V	0.827	1.00
272_P	309_S	0.826	1.00
395_Q	406_T	0.825	1.00
26_G	29_V	0.824	1.00
171_V	483_G	0.822	1.00
481_T	516_N	0.821	1.00
256_P	319_F	0.821	1.00
88_A	91_M	0.821	1.00
189_P	224_S	0.819	1.00
513_G	529_Y	0.818	1.00
567_I	571_G	0.817	1.00
665_L	693_A	0.816	1.00
108_G	166_R	0.815	1.00
21_A	24_V	0.815	1.00
246_Y	250_P	0.815	1.00
390_V	394_L	0.814	1.00
93_L	664_T	0.814	1.00
574_Y	622_T	0.814	1.00
79_V	83_I	0.812	1.00
22_T	25_S	0.812	1.00
83_I	163_E	0.811	1.00
20_V	23_A	0.811	1.00
718_D	736_E	0.810	1.00
464_Q	535_P	0.810	1.00
107_P	620_S	0.809	1.00
409_T	413_F	0.808	1.00
193_P	216_S	0.806	1.00
654_T	698_D	0.805	1.00
123_L	182_L	0.803	1.00
390_V	413_F	0.803	1.00
223_Y	227_L	0.798	1.00
74_T	78_K	0.797	1.00
552_K	577_T	0.794	1.00
662_G	698_D	0.794	1.00
143_K	176_S	0.793	1.00
315_V	335_F	0.792	1.00
578_K	581_N	0.792	1.00
611_L	651_A	0.791	1.00
654_T	662_G	0.791	1.00
61_I	67_A	0.791	1.00
645_H	671_Y	0.790	1.00
111_V	123_L	0.789	1.00
173_Y	181_L	0.786	1.00
17_A	21_A	0.786	1.00
407_L	411_V	0.786	1.00
393_Q	408_L	0.785	1.00
650_W	666_G	0.783	1.00
162_A	184_M	0.781	1.00
647_A	689_T	0.779	1.00
246_Y	270_N	0.779	1.00
684_K	723_A	0.779	1.00
675_S	686_G	0.778	1.00
706_G	745_F	0.778	1.00
469_V	484_G	0.775	1.00
60_T	65_Q	0.774	1.00
617_V	624_T	0.773	1.00
556_V	560_Y	0.773	1.00
212_D	228_T	0.772	1.00
392_T	411_V	0.771	1.00
233_S	242_E	0.769	1.00
625_D	644_K	0.769	1.00
550_K	579_T	0.767	1.00
232_R	245_R	0.766	1.00
598_I	639_P	0.765	1.00
698_D	706_G	0.765	1.00
634_Y	637_N	0.764	1.00
617_V	621_Y	0.764	1.00
343_N	380_V	0.764	1.00
624_T	642_V	0.764	1.00
618_V	652_D	0.761	1.00
60_T	63_A	0.760	1.00
619_G	647_A	0.757	1.00
326_T	397_K	0.756	1.00
97_K	101_E	0.756	1.00
419_D	459_L	0.754	1.00
104_S	670_R	0.753	1.00
644_K	673_G	0.753	1.00
417_R	461_K	0.753	1.00
664_T	667_T	0.752	1.00
141_G	183_N	0.751	1.00
693_A	713_V	0.751	1.00
387_N	416_M	0.751	1.00
62_A	67_A	0.751	1.00
388_F	392_T	0.750	1.00
22_T	26_G	0.749	1.00
614_S	655_F	0.749	1.00
216_S	224_S	0.748	1.00
74_T	472_Q	0.747	1.00
510_T	531_E	0.747	1.00
718_D	737_R	0.746	1.00
323_F	327_F	0.745	1.00
614_S	617_V	0.743	1.00
193_P	199_F	0.741	1.00
408_L	470_Q	0.739	1.00
124_I	129_A	0.737	1.00
313_K	337_E	0.736	1.00
24_V	27_M	0.736	1.00
407_L	469_V	0.735	1.00
147_N	151_D	0.734	1.00
19_V	23_A	0.734	1.00
61_I	65_Q	0.734	1.00
480_V	484_G	0.734	1.00
62_A	66_S	0.733	1.00
325_D	398_F	0.730	1.00
676_Y	685_V	0.729	1.00
99_V	102_A	0.729	1.00
197_V	211_F	0.728	1.00
24_V	28_S	0.728	1.00
125_I	164_I	0.728	1.00
224_S	261_N	0.726	1.00
30_Y	33_A	0.726	1.00
272_P	307_T	0.725	1.00
82_S	555_E	0.725	1.00
191_T	255_R	0.724	1.00
249_A	267_Y	0.724	1.00
147_N	152_A	0.724	1.00
549_S	581_N	0.722	1.00
387_N	414_M	0.721	1.00
568_V	610_A	0.720	1.00
189_P	253_T	0.720	1.00
187_K	212_D	0.719	1.00
617_V	620_S	0.719	1.00
565_R	569_V	0.718	1.00
271_E	310_R	0.717	1.00
192_E	195_K	0.712	1.00
156_P	159_L	0.711	1.00
412_D	468_Y	0.709	1.00
617_V	622_T	0.709	1.00
708_N	711_L	0.709	1.00
489_A	506_D	0.708	1.00
470_Q	512_R	0.707	1.00
607_A	619_G	0.707	1.00
201_A	209_T	0.706	1.00
578_K	598_I	0.706	1.00
84_S	107_P	0.705	1.00
622_T	628_Y	0.704	1.00
172_L	408_L	0.703	1.00
17_A	24_V	0.703	1.00
686_G	719_R	0.703	1.00
126_R	574_Y	0.702	1.00
520_D	560_Y	0.699	1.00
609_A	612_S	0.698	1.00
653_Y	665_L	0.698	1.00
735_A	738_Q	0.697	1.00
405_H	409_T	0.697	1.00
717_F	720_E	0.696	1.00
206_L	234_A	0.695	1.00
655_F	662_G	0.695	1.00
577_T	629_T	0.694	1.00
508_Q	531_E	0.694	1.00
147_N	150_N	0.694	1.00
389_S	414_M	0.693	1.00
475_W	515_V	0.692	1.00
157_Y	198_Q	0.692	1.00
20_V	24_V	0.692	1.00
226_R	249_A	0.692	1.00
32_Q	36_E	0.690	1.00
403_I	410_G	0.689	1.00
251_A	265_L	0.688	1.00
506_D	548_P	0.688	1.00
576_L	600_A	0.687	1.00
479_L	482_L	0.687	1.00
697_Y	700_A	0.687	1.00
254_W	257_D	0.685	1.00
142_L	316_G	0.684	1.00
165_M	173_Y	0.684	1.00
260_T	264_F	0.683	1.00
471_D	482_L	0.683	1.00
712_H	742_T	0.682	1.00
537_S	546_F	0.682	1.00
82_S	572_A	0.679	1.00
327_F	409_T	0.678	1.00
176_S	464_Q	0.677	1.00
342_Q	381_D	0.677	1.00
319_F	331_Q	0.677	1.00
482_L	486_Y	0.676	1.00
616_N	619_G	0.676	1.00
339_K	384_K	0.676	1.00
512_R	528_S	0.675	1.00
126_R	602_G	0.673	1.00
18_V	22_T	0.672	1.00
624_T	646_M	0.671	1.00
607_A	611_L	0.670	1.00
463_K	490_D	0.670	1.00
316_G	334_R	0.669	1.00
92_A	744_T	0.669	1.00
416_M	462_Q	0.669	1.00
193_P	225_Y	0.668	1.00
76_I	85_V	0.668	1.00
634_Y	639_P	0.667	1.00
513_G	517_Y	0.666	1.00
165_M	181_L	0.666	1.00
21_A	25_S	0.665	1.00
462_Q	535_P	0.664	1.00
741_A	744_T	0.662	1.00
223_Y	256_P	0.662	1.00
194_L	746_R	0.661	1.00
332_N	393_Q	0.660	1.00
202_G	205_S	0.660	1.00
408_L	472_Q	0.659	1.00
188_R	265_L	0.659	1.00
739_V	743_A	0.658	1.00
322_E	325_D	0.658	1.00
200_K	740_V	0.658	1.00
582_L	592_S	0.657	1.00
638_T	676_Y	0.655	1.00
110_S	643_P	0.655	1.00
651_A	655_F	0.654	1.00
166_R	606_E	0.653	1.00
665_L	669_G	0.653	1.00
327_F	407_L	0.650	1.00
536_S	539_V	0.650	1.00
109_V	123_L	0.649	1.00
606_E	618_V	0.649	1.00
606_E	620_S	0.646	1.00
646_M	672_T	0.646	1.00
203_T	739_V	0.646	1.00
217_L	225_Y	0.645	1.00
137_N	184_M	0.645	1.00
68_T	71_K	0.644	1.00
197_V	745_F	0.643	1.00
195_K	211_F	0.643	1.00
599_R	627_E	0.643	1.00
168_P	530_S	0.642	1.00
475_W	478_V	0.642	1.00
77_Q	561_V	0.641	1.00
136_N	177_S	0.641	1.00
30_Y	34_A	0.640	1.00
233_S	246_Y	0.639	1.00
546_F	582_L	0.638	1.00
464_Q	489_A	0.636	1.00
33_A	36_E	0.635	1.00
321_H	324_N	0.633	1.00
217_L	223_Y	0.633	1.00
90_E	94_H	0.633	1.00
237_Q	240_G	0.631	1.00
562_P	565_R	0.630	1.00
197_V	200_K	0.630	1.00
259_K	323_F	0.630	1.00
568_V	571_G	0.630	1.00
263_T	330_R	0.627	1.00
191_T	216_S	0.627	1.00
388_F	415_R	0.626	1.00
63_A	66_S	0.625	1.00
315_V	319_F	0.625	1.00
23_A	26_G	0.624	1.00
398_F	405_H	0.622	1.00
743_A	747_F	0.622	1.00
508_Q	548_P	0.620	1.00
414_M	464_Q	0.620	1.00
253_T	256_P	0.619	1.00
511_W	514_G	0.619	1.00
477_K	521_N	0.618	1.00
188_R	261_N	0.618	1.00
625_D	628_Y	0.617	1.00
699_L	706_G	0.617	1.00
615_V	619_G	0.617	1.00
649_L	689_T	0.615	1.00
60_T	64_R	0.615	1.00
477_K	518_L	0.615	1.00
160_E	190_T	0.615	1.00
143_K	389_S	0.614	1.00
663_L	667_T	0.614	1.00
560_Y	564_D	0.614	1.00
135_Q	179_G	0.612	1.00
70_T	74_T	0.611	1.00
211_F	229_G	0.610	1.00
637_N	676_Y	0.609	1.00
394_L	409_T	0.606	1.00
16_I	23_A	0.606	1.00
244_Q	272_P	0.606	1.00
319_F	323_F	0.605	1.00
644_K	674_S	0.604	1.00
136_N	181_L	0.604	1.00
102_A	156_P	0.603	1.00
585_D	591_F	0.603	1.00
655_F	663_L	0.601	1.00
600_A	624_T	0.600	1.00
627_E	636_G	0.600	1.00
403_I	412_D	0.600	1.00
477_K	522_G	0.599	1.00
128_F	179_G	0.599	1.00
101_E	714_N	0.599	1.00
331_Q	335_F	0.599	1.00
691_V	713_V	0.598	1.00
193_P	196_E	0.598	1.00
168_P	532_S	0.597	1.00
470_Q	483_G	0.595	1.00
341_S	382_D	0.594	1.00
223_Y	250_P	0.594	1.00
80_P	481_T	0.594	1.00
93_L	654_T	0.594	1.00
165_M	169_V	0.594	1.00
689_T	717_F	0.593	1.00
317_Y	321_H	0.593	1.00
566_P	611_L	0.591	1.00
200_K	710_A	0.590	1.00
582_L	594_E	0.590	1.00
528_S	555_E	0.590	1.00
155_D	210_G	0.590	1.00
198_Q	201_A	0.589	1.00
386_Q	417_R	0.589	1.00
669_G	717_F	0.588	1.00
70_T	73_D	0.587	1.00
403_I	407_L	0.586	1.00
518_L	522_G	0.585	1.00
341_S	380_V	0.585	1.00
558_V	569_V	0.585	1.00
144_L	314_M	0.584	1.00
204_D	738_Q	0.583	1.00
673_G	689_T	0.583	1.00
420_I	458_I	0.583	1.00
394_L	397_K	0.582	1.00
316_G	332_N	0.581	1.00
526_Y	570_T	0.580	1.00
564_D	567_I	0.580	1.00
604_E	622_T	0.579	1.00
473_A	480_V	0.577	1.00
517_Y	522_G	0.577	1.00
640_A	676_Y	0.576	1.00
112_G	122_H	0.575	1.00
406_T	409_T	0.574	1.00
99_V	159_L	0.574	1.00
243_E	271_E	0.572	1.00
157_Y	228_T	0.572	1.00
562_P	566_P	0.572	1.00
403_I	408_L	0.571	1.00
96_P	101_E	0.571	1.00
695_V	699_L	0.571	1.00
626_A	642_V	0.570	1.00
128_F	132_G	0.568	1.00
405_H	408_L	0.568	1.00
128_F	578_K	0.568	1.00
646_M	670_R	0.567	1.00
626_A	639_P	0.566	1.00
185_V	188_R	0.566	1.00
206_L	232_R	0.566	1.00
82_S	166_R	0.566	1.00
77_Q	518_L	0.562	1.00
189_P	226_R	0.561	1.00
213_F	216_S	0.560	1.00
265_L	318_S	0.559	1.00
57_P	60_T	0.559	1.00
649_L	669_G	0.558	1.00
146_G	151_D	0.558	1.00
519_F	522_G	0.558	1.00
701_R	707_S	0.557	1.00
385_L	418_N	0.556	1.00
322_E	326_T	0.556	1.00
394_L	398_F	0.556	1.00
547_A	550_K	0.556	1.00
102_A	106_T	0.556	1.00
203_T	206_L	0.556	1.00
23_A	27_M	0.556	1.00
651_A	669_G	0.556	1.00
167_G	555_E	0.555	1.00
398_F	403_I	0.555	1.00
236_A	241_S	0.553	1.00
533_F	550_K	0.553	1.00
157_Y	196_E	0.552	1.00
171_V	470_Q	0.552	1.00
128_F	600_A	0.551	1.00
250_P	253_T	0.550	1.00
422_A	456_Y	0.550	1.00
691_V	695_V	0.550	1.00
158_M	247_A	0.549	1.00
331_Q	388_F	0.549	1.00
513_G	516_N	0.549	1.00
321_H	329_V	0.548	1.00
32_Q	35_V	0.548	1.00
447_A	450_P	0.548	1.00
474_Q	518_L	0.547	1.00
193_P	201_A	0.546	1.00
610_A	614_S	0.546	1.00
58_A	62_A	0.546	1.00
648_S	668_G	0.544	1.00
554_Y	573_V	0.544	1.00
614_S	628_Y	0.544	1.00
465_T	490_D	0.543	1.00
178_P	532_S	0.542	1.00
107_P	166_R	0.541	1.00
18_V	25_S	0.541	1.00
619_G	623_Y	0.540	1.00
237_Q	736_E	0.540	1.00
517_Y	520_D	0.540	1.00
643_P	672_T	0.540	1.00
640_A	644_K	0.540	1.00
648_S	670_R	0.539	1.00
662_G	699_L	0.539	1.00
643_P	675_S	0.538	1.00
662_G	700_A	0.538	1.00
635_K	638_T	0.538	1.00
190_T	224_S	0.537	1.00
512_R	530_S	0.536	1.00
617_V	623_Y	0.536	1.00
611_L	614_S	0.535	1.00
76_I	83_I	0.535	1.00
155_D	208_Q	0.535	1.00
541_K	591_F	0.534	1.00
90_E	618_V	0.534	1.00
77_Q	524_T	0.534	1.00
667_T	716_L	0.533	1.00
56_G	59_A	0.532	1.00
256_P	259_K	0.531	1.00
138_Y	173_Y	0.530	1.00
81_Q	512_R	0.530	1.00
405_H	412_D	0.529	1.00
245_R	271_E	0.528	1.00
213_F	225_Y	0.528	1.00
693_A	711_L	0.528	1.00
329_V	390_V	0.527	1.00
107_P	110_S	0.527	1.00
698_D	701_R	0.526	1.00
462_Q	489_A	0.526	1.00
250_P	266_S	0.526	1.00
490_D	505_D	0.526	1.00
532_S	553_Q	0.526	1.00
110_S	672_T	0.525	1.00
34_A	37_P	0.525	1.00
615_V	628_Y	0.524	1.00
16_I	24_V	0.523	1.00
327_F	331_Q	0.523	1.00
192_E	216_S	0.522	1.00
80_P	83_I	0.521	1.00
306_N	342_Q	0.521	1.00
105_Y	650_W	0.520	1.00
249_A	265_L	0.520	1.00
311_N	339_K	0.520	1.00
16_I	22_T	0.519	1.00
408_L	412_D	0.518	1.00
611_L	615_V	0.517	1.00
36_E	55_W	0.517	1.00
125_I	135_Q	0.517	1.00
172_L	468_Y	0.515	1.00
695_V	711_L	0.515	1.00
78_K	474_Q	0.515	1.00
115_G	118_N	0.515	1.00
468_Y	485_R	0.515	1.00
336_A	387_N	0.514	1.00
581_N	596_G	0.514	1.00
605_I	621_Y	0.514	1.00
259_K	324_N	0.513	1.00
405_H	474_Q	0.512	1.00
581_N	600_A	0.512	1.00
694_L	708_N	0.509	1.00
178_P	534_E	0.508	1.00
389_S	412_D	0.508	1.00
566_P	612_S	0.508	1.00
504_R	547_A	0.507	1.00
625_D	638_T	0.507	1.00
557_G	570_T	0.507	1.00
252_F	264_F	0.506	1.00
207_F	231_A	0.505	1.00
578_K	600_A	0.505	1.00
103_L	109_V	0.505	1.00
523_V	562_P	0.504	1.00
195_K	747_F	0.504	1.00
699_L	743_A	0.504	1.00
270_N	313_K	0.504	1.00
382_D	421_N	0.504	1.00
104_S	692_D	0.503	1.00
651_A	665_L	0.502	1.00
317_Y	333_L	0.502	1.00
384_K	419_D	0.502	1.00
533_F	548_P	0.501	1.00
513_G	527_F	0.501	1.00
618_V	666_G	0.501	1.00
104_S	111_V	0.501	1.00
465_T	469_V	0.501	1.00
144_L	336_A	0.501	1.00
549_S	580_N	0.500	1.00
28_S	31_A	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3qlbA	1	0.8929	100	0.249	Contact Map
4cu4A	1	0.925	100	0.255	Contact Map
3efmA	1	0.7497	100	0.262	Contact Map
1kmoA	1	0.83	100	0.267	Contact Map
1xkwA	1	0.8608	100	0.272	Contact Map
2w16A	1	0.9317	100	0.273	Contact Map
2gufA	1	0.7202	100	0.318	Contact Map
3v8xA	1	0.8594	100	0.318	Contact Map
2hdiA	1	0.7242	100	0.324	Contact Map
3cslA	1	0.8046	100	0.332	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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