AGAL - ECOLI - GREMLIN Contacts

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AGAL - Alpha-galactosidase

UniProt:	P06720	Sequences: MMSAPKITFIGAGSTIFVKNILGDVFHREALKTAHIALMDIDPTRLEESHIVVRKLMDSAGASGKITCHTQQKEALEDADFVVVAFQIGGYEPCTVTDFEVCKRHGLEQTIADTLGPGGIMRALRTIPHLWQICEDMTEVCPDATMLNYVNPMAMNTWAMYARYPHIKQVGLCHSVQGTAEELARDLNIDPATLRYRCAGINHMAFYLELERKTADGSYVNLYPELLAAYEAGQAPKPNIHGNTRCQNIVRYEMFKKLGYFVTESSEHFAEYTPWFIKPGREDLIERYKVPLDEYPKRCVEQLANWHKELEEYKKASRIDIKPSREYASTIMNAIWTGEPSVIYGNVRNDGLIDNLPQGCCVEVACLVDANGIQPTKVGTLPSHLAALMQTNINVQTLLTEAILTENRDRVYHAAMMDPHTAAVLGIDEIYALVDDLIAAHGDWLPGWLHR	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10577
Length:	451 (414)
Sequences:	1740 (1020)
Seq/√Len:	50.1

ECOLI - AGAL CHBF GLVG
BACSU - AGAL LICH GLVA LPLD

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
73_K	139_E	5.796	1.00
193_T	213_K	4.687	1.00
81_F	336_W	4.172	1.00
76_L	141_C	3.979	1.00
72_Q	136_D	3.965	1.00
104_R	436_D	3.498	1.00
137_M	146_M	3.393	1.00
50_H	68_C	3.318	1.00
369_D	374_Q	3.230	1.00
412_Y	434_V	3.224	1.00
408_R	435_D	3.216	1.00
71_Q	74_E	3.143	1.00
334_A	341_S	3.139	1.00
137_M	167_I	3.104	1.00
73_K	136_D	3.078	1.00
35_H	65_K	2.967	1.00
107_L	433_L	2.907	1.00
345_G	368_V	2.879	1.00
35_H	67_T	2.823	1.00
190_D	193_T	2.680	1.00
354_D	380_T	2.664	1.00
50_H	54_R	2.628	1.00
6_K	37_A	2.602	1.00
292_L	300_V	2.554	1.00
209_E	216_D	2.550	1.00
352_L	362_V	2.490	1.00
381_L	389_M	2.490	1.00
138_T	165_P	2.454	1.00
170_V	373_I	2.406	1.00
405_T	410_R	2.392	1.00
411_V	434_V	2.379	1.00
47_E	51_I	2.359	1.00
37_A	67_T	2.342	1.00
88_I	129_H	2.317	1.00
120_I	399_L	2.292	1.00
132_Q	135_E	2.236	1.00
135_E	138_T	2.212	1.00
105_H	432_A	2.196	1.00
137_M	141_C	2.195	1.00
345_G	366_C	2.193	1.00
134_C	160_M	2.168	1.00
350_D	358_Q	2.155	1.00
212_R	222_L	2.123	1.00
107_L	117_P	2.096	1.00
355_N	386_A	2.069	1.00
138_T	166_H	2.064	1.00
302_Q	318_R	2.061	1.00
356_L	389_M	2.054	1.00
222_L	225_E	2.020	1.00
30_A	333_N	1.993	1.00
253_E	276_F	1.986	1.00
105_H	436_D	1.961	0.99
47_E	50_H	1.954	0.99
73_K	140_V	1.946	0.99
57_M	66_I	1.926	0.99
127_I	159_A	1.923	0.99
108_E	285_I	1.910	0.99
74_E	77_E	1.908	0.99
161_Y	348_R	1.881	0.99
145_T	168_K	1.869	0.99
225_E	229_A	1.864	0.99
401_E	405_T	1.857	0.99
351_G	358_Q	1.854	0.99
131_W	159_A	1.782	0.99
333_N	337_T	1.776	0.99
97_T	440_A	1.769	0.99
21_I	36_I	1.761	0.99
284_L	288_Y	1.759	0.99
401_E	410_R	1.733	0.99
37_A	69_H	1.732	0.99
407_N	410_R	1.708	0.99
127_I	155_M	1.700	0.98
367_L	376_T	1.693	0.98
81_F	335_I	1.689	0.98
6_K	35_H	1.685	0.98
215_A	225_E	1.666	0.98
92_E	96_V	1.661	0.98
340_P	369_D	1.647	0.98
410_R	413_H	1.645	0.98
126_T	129_H	1.640	0.98
335_I	338_G	1.635	0.98
197_R	209_E	1.598	0.98
51_I	54_R	1.581	0.98
143_D	168_K	1.577	0.97
31_L	332_M	1.570	0.97
117_P	421_T	1.542	0.97
120_I	395_V	1.533	0.97
160_M	169_Q	1.530	0.97
80_D	143_D	1.520	0.97
369_D	372_G	1.519	0.97
130_L	160_M	1.502	0.97
355_N	379_G	1.501	0.97
13_G	40_D	1.474	0.96
67_T	74_E	1.470	0.96
354_D	379_G	1.456	0.96
8_T	79_A	1.452	0.96
96_V	296_P	1.438	0.96
314_K	317_S	1.436	0.96
342_V	367_L	1.436	0.96
115_L	392_N	1.434	0.96
317_S	320_D	1.433	0.96
43_P	47_E	1.432	0.96
386_A	390_Q	1.424	0.95
57_M	64_G	1.401	0.95
271_E	275_W	1.393	0.95
134_C	137_M	1.385	0.95
402_A	411_V	1.369	0.94
369_D	373_I	1.358	0.94
433_L	437_L	1.357	0.94
127_I	403_I	1.356	0.94
206_F	277_I	1.353	0.94
78_D	143_D	1.349	0.94
403_I	406_E	1.343	0.94
105_H	433_L	1.343	0.94
354_D	358_Q	1.340	0.94
69_H	75_A	1.334	0.93
131_W	404_L	1.328	0.93
82_V	137_M	1.321	0.93
415_A	437_L	1.311	0.93
101_V	440_A	1.296	0.92
8_T	37_A	1.293	0.92
42_D	90_G	1.285	0.92
301_E	305_N	1.274	0.92
107_L	429_E	1.273	0.92
439_A	442_G	1.271	0.92
8_T	76_L	1.266	0.92
343_I	368_V	1.265	0.92
295_Y	299_C	1.262	0.91
187_L	226_L	1.253	0.91
193_T	212_R	1.250	0.91
371_N	374_Q	1.246	0.91
77_E	140_V	1.245	0.91
84_V	130_L	1.243	0.91
272_Y	275_W	1.242	0.91
7_I	31_L	1.235	0.91
231_E	256_K	1.232	0.90
195_R	211_E	1.231	0.90
212_R	215_A	1.229	0.90
96_V	100_E	1.229	0.90
97_T	441_H	1.227	0.90
199_A	381_L	1.199	0.89
34_A	65_K	1.186	0.89
47_E	68_C	1.179	0.88
355_N	390_Q	1.178	0.88
128_P	403_I	1.174	0.88
199_A	208_L	1.170	0.88
82_V	144_A	1.170	0.88
164_Y	167_I	1.165	0.88
383_S	394_N	1.164	0.88
30_A	339_E	1.159	0.87
415_A	430_I	1.154	0.87
54_R	58_D	1.153	0.87
296_P	299_C	1.150	0.87
273_T	277_I	1.133	0.86
98_D	125_R	1.128	0.86
39_M	75_A	1.127	0.86
384_H	413_H	1.123	0.86
204_M	392_N	1.116	0.85
408_R	434_V	1.109	0.85
76_L	140_V	1.107	0.85
224_P	228_A	1.104	0.85
92_E	97_T	1.104	0.85
354_D	377_K	1.103	0.85
225_E	228_A	1.101	0.85
273_T	276_F	1.101	0.85
5_P	336_W	1.095	0.84
352_L	364_V	1.094	0.84
204_M	388_L	1.092	0.84
342_V	376_T	1.083	0.84
416_M	427_I	1.074	0.83
87_Q	95_T	1.074	0.83
96_V	293_D	1.069	0.83
46_L	68_C	1.067	0.83
271_E	276_F	1.059	0.82
216_D	223_Y	1.055	0.82
107_L	422_A	1.052	0.82
338_G	370_A	1.048	0.82
212_R	216_D	1.045	0.81
412_Y	430_I	1.043	0.81
395_V	415_A	1.042	0.81
154_A	396_Q	1.041	0.81
10_I	146_M	1.040	0.81
121_M	438_I	1.034	0.81
86_F	153_M	1.034	0.81
195_R	342_V	1.032	0.81
95_T	99_F	1.031	0.80
189_I	212_R	1.031	0.80
130_L	156_N	1.030	0.80
158_W	397_T	1.027	0.80
119_G	125_R	1.022	0.80
305_N	308_K	1.019	0.80
114_T	119_G	1.017	0.80
308_K	312_E	1.015	0.79
8_T	39_M	1.014	0.79
53_V	66_I	1.009	0.79
178_G	182_E	1.007	0.79
86_F	133_I	1.004	0.79
408_R	438_I	1.004	0.79
254_M	258_L	1.002	0.79
367_L	374_Q	0.999	0.78
306_W	318_R	0.995	0.78
411_V	438_I	0.995	0.78
421_T	430_I	0.993	0.78
102_C	437_L	0.992	0.78
347_V	366_C	0.992	0.78
198_C	207_Y	0.989	0.78
271_E	277_I	0.987	0.77
408_R	431_Y	0.985	0.77
180_A	196_Y	0.983	0.77
102_C	105_H	0.981	0.77
412_Y	431_Y	0.978	0.77
138_T	163_R	0.978	0.77
342_V	365_A	0.976	0.77
10_I	133_I	0.976	0.77
406_E	447_G	0.975	0.77
109_Q	118_G	0.973	0.76
136_D	140_V	0.968	0.76
274_P	277_I	0.966	0.76
5_P	34_A	0.956	0.75
422_A	429_E	0.944	0.74
135_E	164_Y	0.942	0.74
121_M	441_H	0.942	0.74
43_P	70_T	0.941	0.74
347_V	368_V	0.938	0.74
173_C	203_H	0.931	0.73
330_T	341_S	0.931	0.73
353_I	362_V	0.931	0.73
416_M	430_I	0.929	0.73
134_C	166_H	0.929	0.73
138_T	167_I	0.927	0.73
333_N	339_E	0.921	0.72
282_E	286_E	0.913	0.72
360_C	393_I	0.908	0.71
292_L	296_P	0.905	0.71
156_N	159_A	0.897	0.70
271_E	274_P	0.896	0.70
392_N	418_D	0.895	0.70
198_C	205_A	0.894	0.70
120_I	415_A	0.891	0.70
272_Y	276_F	0.891	0.70
132_Q	136_D	0.887	0.70
250_V	254_M	0.879	0.69
115_L	418_D	0.874	0.68
271_E	279_P	0.871	0.68
81_F	332_M	0.870	0.68
415_A	433_L	0.870	0.68
366_C	375_P	0.870	0.68
123_A	127_I	0.867	0.68
355_N	362_V	0.866	0.68
135_E	139_E	0.865	0.68
294_E	298_R	0.858	0.67
298_R	302_Q	0.853	0.67
360_C	397_T	0.847	0.66
145_T	335_I	0.846	0.66
296_P	300_V	0.845	0.66
102_C	433_L	0.845	0.66
432_A	435_D	0.844	0.66
88_I	126_T	0.842	0.66
149_Y	328_A	0.842	0.66
255_F	258_L	0.841	0.65
79_A	141_C	0.841	0.65
170_V	335_I	0.840	0.65
186_D	226_L	0.838	0.65
228_A	232_A	0.838	0.65
92_E	297_K	0.833	0.65
294_E	303_L	0.833	0.65
180_A	207_Y	0.832	0.65
355_N	380_T	0.831	0.64
368_V	373_I	0.826	0.64
117_P	415_A	0.826	0.64
283_D	287_R	0.826	0.64
163_R	167_I	0.822	0.64
181_E	191_P	0.818	0.63
190_D	212_R	0.816	0.63
87_Q	99_F	0.815	0.63
192_A	213_K	0.809	0.62
129_H	132_Q	0.809	0.62
153_M	176_V	0.809	0.62
300_V	304_A	0.809	0.62
54_R	74_E	0.807	0.62
164_Y	404_L	0.806	0.62
408_R	412_Y	0.805	0.62
216_D	232_A	0.805	0.62
229_A	233_G	0.802	0.62
437_L	440_A	0.801	0.62
189_I	193_T	0.801	0.62
12_A	430_I	0.798	0.61
123_A	361_C	0.793	0.61
54_R	65_K	0.793	0.61
76_L	82_V	0.791	0.61
282_E	429_E	0.789	0.60
252_Y	256_K	0.788	0.60
197_R	378_V	0.783	0.60
9_F	83_V	0.783	0.60
121_M	437_L	0.782	0.60
406_E	446_P	0.781	0.60
438_I	442_G	0.779	0.59
134_C	163_R	0.779	0.59
205_A	263_T	0.779	0.59
98_D	119_G	0.778	0.59
6_K	79_A	0.776	0.59
398_L	413_H	0.774	0.59
44_T	358_Q	0.771	0.59
344_Y	365_A	0.771	0.59
215_A	222_L	0.769	0.58
43_P	228_A	0.766	0.58
102_C	118_G	0.766	0.58
293_D	296_P	0.762	0.58
357_P	360_C	0.755	0.57
158_W	393_I	0.751	0.57
394_N	397_T	0.751	0.57
412_Y	415_A	0.751	0.57
72_Q	132_Q	0.750	0.57
177_Q	331_I	0.749	0.56
147_L	332_M	0.749	0.56
72_Q	76_L	0.748	0.56
275_W	284_L	0.748	0.56
353_I	379_G	0.746	0.56
316_A	319_I	0.744	0.56
184_A	189_I	0.743	0.56
16_I	85_A	0.735	0.55
49_S	53_V	0.734	0.55
387_A	394_N	0.733	0.55
146_M	160_M	0.727	0.54
209_E	223_Y	0.726	0.54
101_V	436_D	0.726	0.54
204_M	418_D	0.725	0.54
432_A	436_D	0.725	0.54
391_T	417_M	0.725	0.54
36_I	435_D	0.718	0.53
275_W	278_K	0.717	0.53
79_A	82_V	0.717	0.53
7_I	24_D	0.717	0.53
109_Q	112_A	0.714	0.53
109_Q	396_Q	0.714	0.53
59_S	313_Y	0.714	0.53
179_T	205_A	0.713	0.53
38_L	53_V	0.711	0.53
47_E	374_Q	0.709	0.52
106_G	290_V	0.709	0.52
114_T	155_M	0.708	0.52
324_S	396_Q	0.704	0.52
139_E	228_A	0.704	0.52
97_T	101_V	0.704	0.52
175_S	263_T	0.703	0.52
186_D	252_Y	0.702	0.52
296_P	303_L	0.702	0.52
56_L	144_A	0.701	0.52
149_Y	154_A	0.701	0.52
334_A	343_I	0.701	0.52
292_L	303_L	0.699	0.51
120_I	411_V	0.698	0.51
157_T	171_G	0.698	0.51
54_R	67_T	0.697	0.51
134_C	165_P	0.694	0.51
174_H	324_S	0.692	0.51
36_I	64_G	0.690	0.50
159_A	403_I	0.689	0.50
69_H	74_E	0.688	0.50
199_A	378_V	0.688	0.50
113_D	122_R	0.685	0.50
254_M	262_V	0.685	0.50
149_Y	327_Y	0.685	0.50
53_V	57_M	0.684	0.50
99_F	113_D	0.681	0.50
161_Y	169_Q	0.681	0.50
304_A	307_H	0.678	0.49
99_F	109_Q	0.677	0.49
275_W	279_P	0.676	0.49
49_S	68_C	0.676	0.49
173_C	202_N	0.675	0.49
23_G	157_T	0.675	0.49
383_S	390_Q	0.675	0.49
146_M	169_Q	0.674	0.49
411_V	446_P	0.671	0.48
135_E	165_P	0.671	0.48
102_C	121_M	0.670	0.48
44_T	47_E	0.668	0.48
206_F	413_H	0.666	0.48
222_L	227_L	0.665	0.48
428_D	432_A	0.664	0.48
251_R	254_M	0.663	0.48
183_L	210_L	0.662	0.48
365_A	382_P	0.660	0.47
58_D	194_L	0.657	0.47
151_N	202_N	0.656	0.47
223_Y	226_L	0.655	0.47
76_L	136_D	0.654	0.47
190_D	213_K	0.652	0.47
364_V	378_V	0.652	0.47
115_L	204_M	0.652	0.47
134_C	164_Y	0.652	0.47
223_Y	227_L	0.650	0.46
198_C	344_Y	0.650	0.46
443_D	446_P	0.650	0.46
44_T	351_G	0.649	0.46
393_I	396_Q	0.648	0.46
126_T	403_I	0.647	0.46
123_A	159_A	0.646	0.46
92_E	443_D	0.644	0.46
57_M	63_S	0.639	0.45
117_P	433_L	0.637	0.45
283_D	350_D	0.637	0.45
355_N	381_L	0.637	0.45
109_Q	113_D	0.637	0.45
12_A	50_H	0.637	0.45
154_A	204_M	0.636	0.45
195_R	209_E	0.635	0.45
389_M	413_H	0.635	0.45
62_A	66_I	0.634	0.45
288_Y	291_P	0.634	0.45
115_L	395_V	0.632	0.44
28_R	334_A	0.631	0.44
25_V	334_A	0.630	0.44
169_Q	361_C	0.629	0.44
67_T	139_E	0.628	0.44
340_P	370_A	0.627	0.44
399_L	415_A	0.625	0.44
17_F	85_A	0.622	0.43
294_E	297_K	0.621	0.43
258_L	272_Y	0.620	0.43
146_M	167_I	0.619	0.43
27_H	329_S	0.617	0.43
114_T	125_R	0.617	0.43
147_L	170_V	0.617	0.43
194_L	212_R	0.615	0.43
26_F	326_E	0.615	0.43
28_R	63_S	0.613	0.43
154_A	392_N	0.612	0.42
292_L	298_R	0.612	0.42
338_G	369_D	0.611	0.42
390_Q	394_N	0.611	0.42
276_F	279_P	0.610	0.42
297_K	301_E	0.610	0.42
46_L	70_T	0.610	0.42
87_Q	396_Q	0.609	0.42
384_H	389_M	0.609	0.42
309_E	316_A	0.609	0.42
51_I	68_C	0.608	0.42
24_D	174_H	0.608	0.42
145_T	170_V	0.608	0.42
149_Y	324_S	0.606	0.42
20_N	324_S	0.606	0.42
358_Q	380_T	0.605	0.42
77_E	135_E	0.604	0.42
15_T	304_A	0.602	0.41
99_F	112_A	0.600	0.41
434_V	438_I	0.600	0.41
14_S	19_K	0.599	0.41
188_N	256_K	0.599	0.41
415_A	421_T	0.599	0.41
134_C	167_I	0.599	0.41
208_L	380_T	0.598	0.41
11_G	14_S	0.597	0.41
82_V	141_C	0.597	0.41
181_E	185_R	0.595	0.41
39_M	76_L	0.594	0.41
256_K	259_G	0.593	0.41
253_E	257_K	0.593	0.41
65_K	213_K	0.593	0.41
273_T	279_P	0.591	0.40
208_L	382_P	0.591	0.40
54_R	143_D	0.591	0.40
304_A	308_K	0.589	0.40
260_Y	263_T	0.588	0.40
150_V	444_W	0.588	0.40
83_V	168_K	0.587	0.40
76_L	115_L	0.586	0.40
30_A	332_M	0.585	0.40
133_I	146_M	0.584	0.40
409_D	413_H	0.584	0.40
175_S	179_T	0.583	0.40
196_Y	207_Y	0.583	0.40
10_I	76_L	0.582	0.40
228_A	256_K	0.581	0.39
253_E	259_G	0.580	0.39
6_K	78_D	0.580	0.39
17_F	20_N	0.579	0.39
87_Q	122_R	0.579	0.39
131_W	164_Y	0.577	0.39
315_K	322_K	0.577	0.39
48_E	311_E	0.576	0.39
163_R	401_E	0.576	0.39
126_T	156_N	0.576	0.39
109_Q	153_M	0.574	0.39
87_Q	109_Q	0.574	0.39
333_N	366_C	0.571	0.38
192_A	215_A	0.570	0.38
151_N	203_H	0.570	0.38
16_I	19_K	0.569	0.38
254_M	273_T	0.568	0.38
382_P	385_L	0.568	0.38
208_L	260_Y	0.567	0.38
180_A	365_A	0.566	0.38
7_I	332_M	0.565	0.38
155_M	423_A	0.564	0.38
104_R	432_A	0.564	0.38
175_S	205_A	0.564	0.38
99_F	396_Q	0.563	0.38
120_I	123_A	0.562	0.38
121_M	141_C	0.562	0.38
226_L	230_Y	0.561	0.37
116_G	125_R	0.561	0.37
58_D	225_E	0.560	0.37
16_I	91_Y	0.560	0.37
305_N	311_E	0.559	0.37
115_L	155_M	0.558	0.37
180_A	210_L	0.558	0.37
19_K	324_S	0.558	0.37
273_T	285_I	0.557	0.37
180_A	194_L	0.557	0.37
223_Y	230_Y	0.557	0.37
36_I	74_E	0.557	0.37
279_P	283_D	0.556	0.37
332_M	379_G	0.555	0.37
131_W	135_E	0.555	0.37
10_I	41_I	0.554	0.37
12_A	53_V	0.553	0.37
84_V	150_V	0.553	0.37
77_E	350_D	0.552	0.37
122_R	126_T	0.551	0.37
213_K	405_T	0.551	0.37
184_A	206_F	0.550	0.36
135_E	166_H	0.550	0.36
95_T	114_T	0.549	0.36
114_T	276_F	0.549	0.36
121_M	390_Q	0.548	0.36
95_T	441_H	0.548	0.36
13_G	41_I	0.548	0.36
151_N	173_C	0.547	0.36
65_K	442_G	0.547	0.36
433_L	436_D	0.546	0.36
431_Y	435_D	0.546	0.36
34_A	63_S	0.546	0.36
298_R	301_E	0.546	0.36
54_R	92_E	0.546	0.36
216_D	397_T	0.545	0.36
403_I	445_L	0.545	0.36
199_A	362_V	0.543	0.36
309_E	314_K	0.543	0.36
309_E	312_E	0.542	0.36
84_V	146_M	0.542	0.36
24_D	332_M	0.542	0.36
175_S	327_Y	0.541	0.36
124_L	403_I	0.540	0.35
8_T	67_T	0.540	0.35
285_I	288_Y	0.539	0.35
103_K	285_I	0.538	0.35
20_N	99_F	0.537	0.35
85_A	296_P	0.537	0.35
335_I	339_E	0.535	0.35
364_V	375_P	0.534	0.35
392_N	396_Q	0.534	0.35
48_E	406_E	0.534	0.35
52_V	59_S	0.534	0.35
155_M	400_T	0.534	0.35
155_M	403_I	0.533	0.35
352_L	376_T	0.533	0.35
176_V	344_Y	0.532	0.35
155_M	338_G	0.532	0.35
95_T	109_Q	0.531	0.35
286_E	435_D	0.530	0.35
395_V	418_D	0.529	0.34
16_I	87_Q	0.529	0.34
395_V	399_L	0.529	0.34
256_K	358_Q	0.529	0.34
7_I	36_I	0.528	0.34
86_F	347_V	0.527	0.34
197_R	208_L	0.527	0.34
319_I	388_L	0.526	0.34
10_I	72_Q	0.526	0.34
8_T	77_E	0.525	0.34
74_E	439_A	0.525	0.34
114_T	122_R	0.524	0.34
96_V	297_K	0.524	0.34
330_T	343_I	0.524	0.34
231_E	439_A	0.524	0.34
350_D	375_P	0.523	0.34
118_G	125_R	0.523	0.34
38_L	66_I	0.522	0.34
98_D	116_G	0.522	0.34
99_F	114_T	0.521	0.34
65_K	190_D	0.520	0.34
140_V	193_T	0.520	0.34
112_A	396_Q	0.519	0.34
187_L	225_E	0.518	0.33
359_G	435_D	0.518	0.33
53_V	85_A	0.517	0.33
357_P	397_T	0.517	0.33
10_I	39_M	0.517	0.33
342_V	374_Q	0.516	0.33
275_W	285_I	0.515	0.33
63_S	413_H	0.514	0.33
19_K	325_R	0.512	0.33
29_E	51_I	0.511	0.33
52_V	197_R	0.511	0.33
386_A	397_T	0.510	0.33
406_E	436_D	0.510	0.33
54_R	187_L	0.509	0.33
189_I	194_L	0.509	0.33
230_Y	247_Q	0.509	0.33
125_R	414_A	0.508	0.33
180_A	191_P	0.508	0.33
28_R	333_N	0.508	0.33
398_L	414_A	0.507	0.32
56_L	60_A	0.507	0.32
171_G	419_P	0.506	0.32
398_L	417_M	0.506	0.32
84_V	169_Q	0.506	0.32
407_N	447_G	0.505	0.32
28_R	64_G	0.505	0.32
105_H	117_P	0.505	0.32
87_Q	103_K	0.505	0.32
163_R	166_H	0.505	0.32
224_P	364_V	0.503	0.32
95_T	112_A	0.503	0.32
254_M	257_K	0.503	0.32
19_K	23_G	0.502	0.32
352_L	359_G	0.502	0.32
158_W	400_T	0.501	0.32
43_P	139_E	0.500	0.32

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1obbA	2	0.949	100	0.368	Contact Map
1s6yA	1	0.8914	100	0.37	Contact Map
1u8xX	1	0.9357	100	0.376	Contact Map
1up7A	3	0.9047	100	0.389	Contact Map
3fefA	3	0.929	100	0.403	Contact Map
3u95A	2	0.9446	100	0.428	Contact Map
1pzgA	4	0.7007	100	0.72	Contact Map
4rorA	4	0.6962	100	0.728	Contact Map
3p7mA	4	0.6763	100	0.729	Contact Map
2hjrA	4	0.6696	100	0.731	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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