GSHR - ECOLI - GREMLIN Contacts

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GSHR - Glutathione reductase

UniProt:	P06715	Sequences: MTKHYDYIAIGGGSGGIASINRAAMYGQKCALIEAKELGGTCVNVGCVPKKVMWHAAQIREAIHMYGPDYGFDTTINKFNWETLIASRTAYIDRIHTSYENVLGKNNVDVIKGFARFVDAKTLEVNGETITADHILIATGGRPSHPDIPGVEYGIDSDGFFALPALPERVAVVGAGYIAVELAGVINGLGAKTHLFVRKHAPLRSFDPMISETLVEVMNAEGPQLHTNAIPKAVVKNTDGSLTLELEDGRSETVDCLIWAIGREPANDNINLEAAGVKTNEKGYIVVDKYQNTNIEGIYAVGDNTGAVELTPVAVAAGRRLSERLFNNKPDEHLDYSNIPTVVFSHPPIGTVGLTEPQAREQYGDDQVKVYKSSFTAMYTAVTTHRQPCRMKLVCVGSEEKIVGIHGIGFGMDEMLQGFAVALKMGATKKDFDNTVAIHPTAAEEFVTMR	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10412
Length:	450 (439)
Sequences:	13607 (8972)
Seq/√Len:	428.2

ECOLI - GSHR STHA DLDH RCLA HCAD NORW DHNA
BACSU - DLDH1 DLDH2 DLDH3 YPDA NASB
HALSA - DLDH Q9HSN0 Q9HP48 Q9HR27
SULSO - Q97VD9 Q97Z19 Q97XZ3 Q97WE3 Q97VQ4 Q97Y24 Q97YT2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
171_A	254_V	4.153	1.00
35_A	114_F	3.939	1.00
288_D	292_N	3.795	1.00
405_I	419_F	2.933	1.00
169_R	192_K	2.925	1.00
278_K	286_V	2.865	1.00
192_K	224_Q	2.689	1.00
194_H	226_H	2.647	1.00
5_Y	109_D	2.613	1.00
119_D	122_T	2.605	1.00
4_H	133_D	2.605	1.00
367_Q	398_S	2.595	1.00
142_R	268_D	2.586	1.00
122_T	129_T	2.581	1.00
271_N	274_A	2.495	1.00
5_Y	31_A	2.492	1.00
215_V	219_N	2.473	1.00
4_H	131_T	2.430	1.00
166_L	191_A	2.411	1.00
418_G	437_A	2.376	1.00
118_V	124_E	2.368	1.00
208_P	357_P	2.356	1.00
396_V	399_E	2.353	1.00
19_S	136_L	2.320	1.00
116_R	124_E	2.316	1.00
132_A	135_I	2.305	1.00
367_Q	397_G	2.303	1.00
142_R	266_A	2.274	1.00
144_S	264_E	2.267	1.00
354_L	362_Q	2.175	1.00
171_A	196_F	2.165	1.00
31_A	111_I	2.161	1.00
169_R	255_D	2.158	1.00
8_I	130_I	2.119	1.00
369_K	397_G	2.115	1.00
400_E	430_K	2.109	1.00
124_E	129_T	2.083	1.00
233_A	245_E	2.069	1.00
7_Y	23_A	2.069	1.00
354_L	359_A	2.065	1.00
280_N	284_Y	2.030	1.00
401_K	426_G	2.020	1.00
243_T	251_S	2.020	1.00
407_G	412_M	2.001	1.00
235_V	245_E	1.995	1.00
321_L	325_L	1.993	1.00
118_V	129_T	1.979	1.00
200_H	228_N	1.954	1.00
156_D	159_G	1.927	1.00
8_I	33_I	1.905	1.00
113_G	125_V	1.904	1.00
122_T	131_T	1.890	1.00
232_K	247_E	1.886	1.00
8_I	123_L	1.885	1.00
180_V	195_L	1.883	1.00
149_P	233_A	1.872	1.00
356_E	360_R	1.835	1.00
243_T	253_T	1.829	1.00
422_A	427_A	1.828	1.00
15_G	301_V	1.821	1.00
73_D	80_N	1.821	1.00
368_V	394_V	1.799	1.00
142_R	264_E	1.794	1.00
73_D	78_K	1.770	1.00
230_I	247_E	1.754	1.00
8_I	132_A	1.720	1.00
117_F	135_I	1.718	1.00
121_K	297_G	1.708	1.00
134_H	297_G	1.707	1.00
357_P	361_E	1.694	1.00
226_H	250_R	1.693	1.00
235_V	243_T	1.687	1.00
187_N	192_K	1.662	1.00
8_I	31_A	1.654	1.00
356_E	392_K	1.654	1.00
289_K	333_H	1.653	1.00
180_V	345_S	1.653	1.00
6_D	133_D	1.645	1.00
137_I	304_N	1.644	1.00
170_V	191_A	1.644	1.00
201_A	211_S	1.633	1.00
292_N	296_E	1.631	1.00
170_V	186_I	1.629	1.00
348_P	413_D	1.628	1.00
245_E	251_S	1.618	1.00
80_N	83_T	1.614	1.00
393_L	405_I	1.608	1.00
10_I	115_A	1.560	1.00
155_I	163_L	1.543	1.00
209_M	372_K	1.526	1.00
198_R	230_I	1.517	1.00
111_I	130_I	1.517	1.00
364_G	403_V	1.509	1.00
136_L	325_L	1.502	1.00
241_S	253_T	1.500	1.00
237_N	243_T	1.493	1.00
226_H	229_A	1.489	1.00
428_T	431_D	1.481	1.00
83_T	86_A	1.479	1.00
155_I	159_G	1.471	1.00
213_T	408_I	1.464	1.00
168_E	255_D	1.455	1.00
358_Q	361_E	1.449	1.00
100_E	112_K	1.446	1.00
59_I	62_A	1.441	1.00
187_N	223_P	1.440	1.00
171_A	244_L	1.432	1.00
299_Y	324_R	1.432	1.00
168_E	192_K	1.430	1.00
134_H	325_L	1.420	1.00
232_K	245_E	1.419	1.00
290_Y	324_R	1.417	1.00
7_Y	28_Q	1.407	1.00
38_L	110_V	1.397	1.00
359_A	394_V	1.387	1.00
207_D	392_K	1.387	1.00
359_A	368_V	1.387	1.00
139_T	304_N	1.367	1.00
6_D	29_K	1.363	1.00
159_G	162_A	1.362	1.00
194_H	224_Q	1.361	1.00
155_I	256_C	1.352	1.00
160_F	186_I	1.346	1.00
22_R	323_E	1.345	1.00
280_N	286_V	1.328	1.00
188_G	221_E	1.327	1.00
33_I	130_I	1.325	1.00
364_G	368_V	1.319	1.00
291_Q	305_T	1.315	1.00
73_D	83_T	1.308	1.00
89_T	93_D	1.297	1.00
7_Y	136_L	1.281	1.00
278_K	294_N	1.273	1.00
367_Q	396_V	1.259	1.00
396_V	401_K	1.258	1.00
31_A	130_I	1.255	1.00
5_Y	111_I	1.247	1.00
209_M	392_K	1.247	1.00
153_Y	236_K	1.233	1.00
116_R	271_N	1.229	1.00
292_N	297_G	1.226	1.00
208_P	212_E	1.225	1.00
217_V	220_A	1.222	1.00
210_I	390_R	1.219	1.00
136_L	301_V	1.218	1.00
275_A	295_I	1.217	1.00
201_A	208_P	1.206	1.00
155_I	160_F	1.204	1.00
196_F	252_E	1.199	1.00
210_I	408_I	1.192	1.00
216_E	219_N	1.186	1.00
425_M	431_D	1.179	1.00
32_L	103_L	1.178	1.00
117_F	137_I	1.176	1.00
45_V	158_D	1.174	1.00
85_I	89_T	1.169	1.00
86_A	90_A	1.167	1.00
206_F	351_T	1.166	1.00
117_F	123_L	1.162	1.00
393_L	419_F	1.162	1.00
229_A	248_D	1.160	1.00
214_L	408_I	1.150	1.00
358_Q	362_Q	1.146	1.00
295_I	298_I	1.139	1.00
349_I	408_I	1.133	1.00
391_M	445_E	1.131	1.00
246_L	252_E	1.131	1.00
124_E	127_G	1.130	1.00
375_F	409_G	1.127	1.00
419_F	446_F	1.125	1.00
201_A	215_V	1.123	1.00
175_A	202_P	1.122	1.00
370_V	394_V	1.118	1.00
173_V	257_L	1.115	1.00
145_H	156_D	1.115	1.00
206_F	341_T	1.113	1.00
33_I	115_A	1.112	1.00
114_F	269_N	1.111	1.00
341_T	351_T	1.110	1.00
36_K	45_V	1.106	1.00
65_M	69_D	1.105	1.00
215_V	227_T	1.104	1.00
100_E	104_G	1.103	1.00
318_G	322_S	1.102	1.00
118_V	122_T	1.101	1.00
197_V	227_T	1.092	1.00
237_N	253_T	1.091	1.00
21_N	106_N	1.089	1.00
215_V	225_L	1.087	1.00
350_G	416_L	1.086	1.00
338_N	423_L	1.085	1.00
148_I	151_V	1.078	1.00
417_Q	438_I	1.075	1.00
411_G	414_E	1.074	1.00
342_V	438_I	1.073	1.00
29_K	109_D	1.071	1.00
60_R	64_H	1.064	1.00
234_V	257_L	1.062	1.00
170_V	256_C	1.059	1.00
125_V	130_I	1.059	1.00
195_L	225_L	1.054	1.00
169_R	241_S	1.049	1.00
285_I	304_N	1.048	1.00
272_L	277_V	1.045	1.00
301_V	321_L	1.044	1.00
267_N	279_T	1.044	1.00
169_R	194_H	1.041	1.00
359_A	364_G	1.036	1.00
356_E	370_V	1.028	1.00
116_R	274_A	1.026	1.00
216_E	220_A	1.024	1.00
364_G	367_Q	1.022	1.00
82_E	164_P	1.020	1.00
63_I	67_G	1.020	1.00
235_V	251_S	1.019	1.00
109_D	128_E	1.019	1.00
427_A	431_D	1.018	1.00
196_F	246_L	1.018	1.00
90_A	94_R	1.016	1.00
417_Q	443_A	1.015	1.00
360_R	368_V	1.014	1.00
202_P	227_T	1.011	1.00
218_M	223_P	1.008	1.00
111_I	128_E	1.007	1.00
10_I	137_I	1.007	1.00
12_G	38_L	1.006	1.00
147_D	151_V	1.004	1.00
81_W	85_I	1.003	1.00
342_V	413_D	1.001	1.00
355_T	358_Q	1.000	1.00
15_G	314_A	0.999	1.00
369_K	400_E	0.998	1.00
12_G	32_L	0.998	1.00
400_E	429_K	0.998	1.00
372_K	390_R	0.996	1.00
320_R	334_L	0.995	1.00
169_R	191_A	0.992	1.00
220_A	388_P	0.987	1.00
28_Q	134_H	0.980	1.00
61_E	64_H	0.979	1.00
291_Q	321_L	0.975	1.00
117_F	132_A	0.974	1.00
165_A	256_C	0.972	1.00
364_G	396_V	0.970	1.00
85_I	88_R	0.970	1.00
28_Q	326_F	0.967	1.00
214_L	349_I	0.966	1.00
169_R	253_T	0.966	1.00
213_T	216_E	0.966	1.00
350_G	412_M	0.961	1.00
74_T	77_N	0.959	1.00
28_Q	133_D	0.959	1.00
93_D	97_T	0.957	1.00
210_I	406_H	0.957	1.00
229_A	246_L	0.955	1.00
33_I	125_V	0.954	1.00
55_H	59_I	0.952	1.00
26_Y	326_F	0.945	1.00
277_V	285_I	0.945	1.00
286_V	294_N	0.943	1.00
275_A	298_I	0.943	1.00
279_T	286_V	0.941	1.00
352_V	423_L	0.936	1.00
237_N	241_S	0.933	1.00
22_R	26_Y	0.929	1.00
154_G	234_V	0.927	1.00
202_P	215_V	0.926	1.00
63_I	74_T	0.925	1.00
26_Y	323_E	0.921	1.00
356_E	394_V	0.918	1.00
175_A	197_V	0.918	1.00
58_Q	62_A	0.918	1.00
170_V	258_I	0.917	1.00
217_V	221_E	0.917	1.00
354_L	358_Q	0.914	1.00
75_T	78_K	0.914	1.00
117_F	274_A	0.912	1.00
226_H	252_E	0.912	1.00
277_V	294_N	0.907	1.00
173_V	259_W	0.907	1.00
56_A	84_L	0.907	1.00
265_P	284_Y	0.907	1.00
61_E	221_E	0.907	1.00
391_M	407_G	0.905	1.00
68_P	83_T	0.905	1.00
173_V	261_I	0.904	1.00
269_N	272_L	0.902	1.00
219_N	224_Q	0.901	1.00
335_D	424_K	0.899	1.00
321_L	324_R	0.899	1.00
117_F	275_A	0.897	1.00
180_V	218_M	0.896	1.00
10_I	123_L	0.895	1.00
202_P	225_L	0.895	1.00
5_Y	29_K	0.891	1.00
287_V	305_T	0.891	1.00
135_I	298_I	0.889	1.00
151_V	154_G	0.886	1.00
356_E	368_V	0.883	1.00
300_A	304_N	0.883	1.00
277_V	295_I	0.881	1.00
171_A	252_E	0.878	1.00
213_T	217_V	0.877	1.00
292_N	299_Y	0.877	1.00
116_R	269_N	0.873	1.00
348_P	411_G	0.873	1.00
33_I	113_G	0.871	1.00
287_V	300_A	0.869	1.00
422_A	432_F	0.862	1.00
320_R	324_R	0.861	1.00
117_F	271_N	0.861	1.00
94_R	382_V	0.860	1.00
57_A	188_G	0.860	1.00
402_I	419_F	0.858	1.00
212_E	215_V	0.856	1.00
308_V	339_I	0.853	1.00
352_V	420_A	0.852	1.00
217_V	388_P	0.850	1.00
42_C	47_C	0.849	1.00
6_D	28_Q	0.847	1.00
210_I	349_I	0.847	1.00
134_H	299_Y	0.846	1.00
169_R	254_V	0.846	1.00
322_S	326_F	0.846	1.00
364_G	394_V	0.844	1.00
99_Y	103_L	0.842	1.00
292_N	324_R	0.840	1.00
103_L	110_V	0.840	1.00
396_V	403_V	0.839	1.00
144_S	261_I	0.836	1.00
53_M	85_I	0.835	1.00
18_A	315_V	0.834	1.00
61_E	65_M	0.831	1.00
56_A	87_S	0.827	1.00
196_F	226_H	0.827	1.00
120_A	297_G	0.826	1.00
101_N	105_K	0.825	1.00
229_A	250_R	0.823	1.00
177_Y	343_V	0.822	1.00
217_V	408_I	0.822	1.00
201_A	212_E	0.822	1.00
236_K	242_L	0.821	1.00
22_R	322_S	0.821	1.00
172_V	258_I	0.819	1.00
212_E	216_E	0.817	1.00
121_K	131_T	0.817	1.00
103_L	108_V	0.811	1.00
179_A	197_V	0.811	1.00
10_I	270_I	0.804	1.00
28_Q	325_L	0.799	1.00
201_A	357_P	0.799	1.00
97_T	100_E	0.797	1.00
194_H	254_V	0.793	1.00
54_W	185_V	0.792	1.00
424_K	434_N	0.789	1.00
276_G	295_I	0.789	1.00
86_A	164_P	0.789	1.00
136_L	321_L	0.788	1.00
284_Y	309_E	0.788	1.00
22_R	25_M	0.788	1.00
418_G	421_V	0.783	1.00
44_N	96_H	0.782	1.00
243_T	246_L	0.782	1.00
113_G	126_N	0.781	1.00
427_A	432_F	0.780	1.00
271_N	275_A	0.779	1.00
187_N	221_E	0.778	1.00
92_I	95_I	0.776	1.00
19_S	318_G	0.775	1.00
355_T	406_H	0.775	1.00
144_S	147_D	0.774	1.00
8_I	135_I	0.772	1.00
323_E	332_E	0.770	1.00
7_Y	322_S	0.770	1.00
291_Q	324_R	0.769	1.00
234_V	242_L	0.769	1.00
172_V	179_A	0.768	1.00
67_G	74_T	0.766	1.00
61_E	188_G	0.765	1.00
82_E	86_A	0.765	1.00
275_A	294_N	0.764	1.00
372_K	392_K	0.763	1.00
68_P	73_D	0.763	1.00
173_V	231_P	0.763	1.00
395_C	429_K	0.761	1.00
23_A	322_S	0.761	1.00
23_A	28_Q	0.759	1.00
359_A	403_V	0.759	1.00
196_F	229_A	0.756	1.00
150_G	156_D	0.754	1.00
313_V	339_I	0.754	1.00
290_Y	333_H	0.753	1.00
139_T	270_I	0.752	1.00
224_Q	250_R	0.752	1.00
50_K	54_W	0.750	1.00
188_G	346_H	0.746	1.00
9_A	16_G	0.743	1.00
121_K	295_I	0.740	1.00
153_Y	256_C	0.739	1.00
203_L	214_L	0.739	1.00
293_T	300_A	0.739	1.00
88_R	92_I	0.734	1.00
19_S	322_S	0.732	1.00
34_E	37_E	0.729	1.00
374_S	377_A	0.727	1.00
394_V	397_G	0.725	1.00
272_L	275_A	0.723	1.00
120_A	276_G	0.723	1.00
363_Y	367_Q	0.722	1.00
375_F	445_E	0.721	1.00
135_I	297_G	0.720	1.00
5_Y	8_I	0.719	1.00
50_K	182_L	0.719	1.00
218_M	225_L	0.719	1.00
213_T	390_R	0.717	1.00
405_I	423_L	0.717	1.00
183_A	195_L	0.716	1.00
214_L	345_S	0.716	1.00
323_E	328_N	0.715	1.00
421_V	427_A	0.715	1.00
88_R	162_A	0.714	1.00
421_V	432_F	0.713	1.00
199_K	204_R	0.712	1.00
268_D	273_E	0.710	1.00
290_Y	329_K	0.709	1.00
275_A	279_T	0.709	1.00
163_L	256_C	0.708	1.00
200_H	208_P	0.706	1.00
337_S	362_Q	0.706	1.00
267_N	304_N	0.704	1.00
206_F	349_I	0.703	1.00
79_F	84_L	0.703	1.00
371_Y	395_C	0.699	1.00
285_I	300_A	0.699	1.00
90_A	93_D	0.698	1.00
401_K	428_T	0.696	1.00
63_I	77_N	0.696	1.00
185_V	189_L	0.696	1.00
37_E	45_V	0.691	1.00
419_F	423_L	0.691	1.00
97_T	101_N	0.690	1.00
145_H	259_W	0.689	1.00
149_P	152_E	0.689	1.00
402_I	423_L	0.688	1.00
421_V	435_T	0.685	1.00
414_E	443_A	0.685	1.00
291_Q	320_R	0.684	1.00
369_K	395_C	0.684	1.00
407_G	415_M	0.682	1.00
56_A	70_Y	0.682	1.00
226_H	246_L	0.680	1.00
206_F	343_V	0.675	1.00
55_H	58_Q	0.674	1.00
73_D	77_N	0.673	1.00
141_G	263_R	0.670	1.00
163_L	186_I	0.666	1.00
207_D	406_H	0.665	1.00
421_V	425_M	0.664	1.00
101_N	104_G	0.662	1.00
19_S	321_L	0.662	1.00
316_A	319_R	0.662	1.00
371_Y	393_L	0.659	0.99
85_I	164_P	0.658	0.99
73_D	76_I	0.658	0.99
395_C	400_E	0.654	0.99
64_H	76_I	0.654	0.99
431_D	434_N	0.652	0.99
429_K	433_D	0.650	0.99
277_V	298_I	0.650	0.99
236_K	241_S	0.649	0.99
184_G	188_G	0.648	0.99
150_G	154_G	0.648	0.99
180_V	202_P	0.648	0.99
67_G	70_Y	0.647	0.99
151_V	234_V	0.646	0.99
89_T	162_A	0.643	0.99
87_S	91_Y	0.643	0.99
120_A	275_A	0.643	0.99
98_S	102_V	0.642	0.99
23_A	30_C	0.641	0.99
399_E	426_G	0.640	0.99
279_T	285_I	0.640	0.99
287_V	291_Q	0.636	0.99
323_E	327_N	0.635	0.99
60_R	63_I	0.635	0.99
183_A	223_P	0.633	0.99
284_Y	306_G	0.632	0.99
198_R	204_R	0.631	0.99
363_Y	368_V	0.630	0.99
24_A	108_V	0.630	0.99
299_Y	325_L	0.629	0.99
354_L	404_G	0.625	0.99
143_P	146_P	0.622	0.99
386_R	410_F	0.622	0.99
317_A	336_Y	0.622	0.99
351_T	406_H	0.622	0.99
179_A	198_R	0.621	0.99
148_I	234_V	0.620	0.99
158_D	161_F	0.618	0.99
292_N	295_I	0.616	0.99
151_V	259_W	0.615	0.99
154_G	259_W	0.615	0.99
122_T	125_V	0.614	0.99
338_N	424_K	0.612	0.99
439_H	444_E	0.612	0.99
63_I	72_F	0.610	0.99
82_E	85_I	0.610	0.99
107_N	110_V	0.609	0.99
160_F	163_L	0.607	0.99
177_Y	341_T	0.607	0.99
368_V	403_V	0.606	0.99
409_G	412_M	0.606	0.99
148_I	231_P	0.605	0.99
83_T	87_S	0.603	0.99
56_A	59_I	0.603	0.99
242_L	257_L	0.603	0.99
242_L	245_E	0.602	0.99
26_Y	328_N	0.600	0.99
184_G	221_E	0.600	0.99
55_H	62_A	0.598	0.99
169_R	187_N	0.597	0.99
405_I	446_F	0.597	0.99
186_I	191_A	0.597	0.99
95_I	382_V	0.597	0.99
155_I	158_D	0.597	0.99
184_G	218_M	0.594	0.99
86_A	89_T	0.594	0.99
197_V	204_R	0.593	0.99
146_P	259_W	0.592	0.99
145_H	151_V	0.591	0.99
237_N	240_G	0.591	0.99
100_E	110_V	0.591	0.99
272_L	279_T	0.590	0.99
253_T	256_C	0.590	0.99
65_M	385_H	0.589	0.99
6_D	31_A	0.588	0.99
84_L	189_L	0.588	0.99
381_A	442_A	0.587	0.99
241_S	255_D	0.586	0.99
35_A	266_A	0.586	0.99
281_E	286_V	0.585	0.99
62_A	65_M	0.584	0.99
424_K	435_T	0.583	0.99
99_Y	102_V	0.583	0.99
196_F	254_V	0.582	0.99
34_E	110_V	0.582	0.99
301_V	318_G	0.580	0.99
210_I	213_T	0.578	0.99
146_P	151_V	0.578	0.99
37_E	96_H	0.575	0.99
380_T	383_T	0.571	0.99
167_P	191_A	0.571	0.99
21_N	25_M	0.569	0.99
420_A	424_K	0.569	0.99
179_A	260_A	0.569	0.99
221_E	346_H	0.569	0.99
323_E	329_K	0.568	0.98
280_N	306_G	0.567	0.98
98_S	101_N	0.565	0.98
118_V	274_A	0.565	0.98
87_S	385_H	0.563	0.98
48_V	379_Y	0.563	0.98
236_K	239_D	0.563	0.98
111_I	125_V	0.563	0.98
246_L	250_R	0.562	0.98
234_V	259_W	0.561	0.98
87_S	90_A	0.561	0.98
313_V	317_A	0.560	0.98
57_A	60_R	0.559	0.98
418_G	443_A	0.558	0.98
430_K	434_N	0.556	0.98
155_I	162_A	0.556	0.98
354_L	364_G	0.554	0.98
241_S	246_L	0.554	0.98
157_S	263_R	0.553	0.98
415_M	442_A	0.553	0.98
69_D	385_H	0.552	0.98
194_H	252_E	0.551	0.98
421_V	437_A	0.550	0.98
4_H	29_K	0.550	0.98
182_L	185_V	0.549	0.98
319_R	323_E	0.548	0.98
9_A	20_I	0.547	0.98
423_L	427_A	0.545	0.98
191_A	255_D	0.544	0.98
387_Q	410_F	0.543	0.98
378_M	381_A	0.543	0.98
150_G	153_Y	0.543	0.98
393_L	402_I	0.543	0.98
313_V	336_Y	0.542	0.98
136_L	322_S	0.542	0.98
213_T	374_S	0.540	0.98
121_K	135_I	0.540	0.98
198_R	261_I	0.539	0.98
229_A	247_E	0.539	0.98
335_D	338_N	0.538	0.98
209_M	390_R	0.538	0.98
285_I	293_T	0.537	0.98
406_H	419_F	0.537	0.98
157_S	178_I	0.537	0.98
70_Y	87_S	0.536	0.98
405_I	416_L	0.536	0.98
9_A	30_C	0.536	0.98
58_Q	346_H	0.535	0.98
37_E	44_N	0.535	0.98
171_A	257_L	0.535	0.98
59_I	63_I	0.535	0.98
323_E	330_P	0.534	0.98
51_K	54_W	0.533	0.98
420_A	435_T	0.532	0.98
316_A	320_R	0.531	0.98
117_F	297_G	0.531	0.98
36_K	112_K	0.529	0.98
242_L	246_L	0.527	0.98
176_G	262_G	0.527	0.98
338_N	420_A	0.527	0.98
24_A	29_K	0.527	0.98
25_M	106_N	0.526	0.98
100_E	103_L	0.526	0.98
57_A	189_L	0.525	0.97
32_L	108_V	0.525	0.97
379_Y	382_V	0.525	0.97
55_H	384_T	0.524	0.97
354_L	363_Y	0.524	0.97
375_F	442_A	0.524	0.97
82_E	165_A	0.522	0.97
158_D	263_R	0.522	0.97
153_Y	242_L	0.522	0.97
67_G	72_F	0.521	0.97
7_Y	19_S	0.521	0.97
184_G	346_H	0.519	0.97
143_P	157_S	0.518	0.97
346_H	410_F	0.517	0.97
182_L	258_I	0.516	0.97
180_V	225_L	0.516	0.97
416_L	438_I	0.516	0.97
246_L	249_G	0.516	0.97
152_E	236_K	0.514	0.97
373_S	377_A	0.512	0.97
417_Q	420_A	0.512	0.97
38_L	100_E	0.512	0.97
351_T	358_Q	0.512	0.97
141_G	309_E	0.512	0.97
375_F	391_M	0.511	0.97
346_H	386_R	0.510	0.97
59_I	67_G	0.508	0.97
197_V	231_P	0.508	0.97
137_I	285_I	0.508	0.97
382_V	387_Q	0.508	0.97
357_P	360_R	0.507	0.97
132_A	297_G	0.505	0.97
338_N	352_V	0.505	0.97
407_G	416_L	0.504	0.97
363_Y	403_V	0.503	0.97
138_A	301_V	0.503	0.97
170_V	193_T	0.502	0.97
89_T	92_I	0.501	0.97
38_L	103_L	0.500	0.97

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2r9zA	2	0.9867	100	0.171	Contact Map
1gesA	2	0.9978	100	0.176	Contact Map
3o0hA	2	0.9822	100	0.178	Contact Map
3dk9A	2	0.9956	100	0.178	Contact Map
2wpfA	2	0.9911	100	0.179	Contact Map
1ojtA	2	0.9867	100	0.186	Contact Map
3ic9A	2	0.9889	100	0.186	Contact Map
4dnaA	2	0.9844	100	0.187	Contact Map
2hqmA	2	0.9889	100	0.188	Contact Map
1lvlA	2	0.9778	100	0.19	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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