DPO3X - ECOLI - GREMLIN Contacts

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DPO3X - DNA polymerase III subunit tau

UniProt:	P06710	Sequences: MSYQVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNCETGITATPCGVCDNCREIEQGRFVDLIEIDAASRTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQKLPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLTDQAIASGDGQVSTQAVSAMLGTLDDDQALSLVEAMVEANGERVMALINEAAARGIEWEALLVEMLGLLHRIAMVQLSPAALGNDMAAIELRMRELARTIPPTDIQLYYQTLLIGRKELPYAPDRRMGVEMTLLRALAFHPRMPLPEPEVPRQSFAPVAPTAVMTPTQVPPQPQSAPQQAPTVPLPETTSQVLAARQQLQRVQGATKAKKSEPAAATRARPVNNAALERLASVTDRVQARPVPSALEKAPAKKEAYRWKATTPVMQQKEVVATPKALKKALEHEKTPELAAKLAAEAIERDPWAAQVSQLSLPKLVEQVALNAWKEESDNAVCLHLRSSQRHLNNRGAQQKLAEALSMLKGSTVELTIVEDDNPAVRTPLEWRQAIYEEKLAQARESIIADNNIQTLRRFFDAELDEESIRPI	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10245
Length:	643 (588)
Sequences:	1726 (1490)
Seq/√Len:	61.4

ECOLI - DPO3X
BACSU - DPO3X

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
33_S	70_A	9.674	1.00
178_L	214_L	5.863	1.00
189_H	193_E	5.426	1.00
81_E	117_R	4.967	1.00
99_T	132_S	4.870	1.00
66_T	75_V	4.464	1.00
75_V	80_R	4.392	1.00
18_V	25_L	4.117	1.00
99_T	134_H	3.676	1.00
188_E	200_P	3.437	1.00
183_I	214_L	3.336	1.00
260_N	263_R	3.132	1.00
268_I	353_L	3.113	1.00
264_V	353_L	3.055	1.00
251_S	270_E	3.045	1.00
371_P	376_A	2.948	1.00
371_P	375_F	2.917	1.00
197_A	231_Q	2.887	1.00
332_L	356_A	2.882	1.00
460_R	468_K	2.836	1.00
289_L	332_L	2.734	1.00
538_Q	541_L	2.719	1.00
187_L	217_A	2.636	1.00
109_D	113_Y	2.590	1.00
335_G	352_T	2.568	1.00
372_R	376_A	2.486	1.00
551_A	587_T	2.485	1.00
474_E	478_W	2.470	1.00
101_V	134_H	2.461	1.00
577_S	583_T	2.386	1.00
234_T	238_S	2.375	1.00
100_K	103_D	2.353	1.00
199_E	233_S	2.347	1.00
252_L	264_V	2.292	1.00
448_E	452_S	2.276	1.00
450_L	453_V	2.264	1.00
515_A	518_I	2.259	1.00
98_R	135_S	2.258	1.00
74_G	83_E	2.256	1.00
346_R	350_E	2.231	1.00
104_T	135_S	2.231	1.00
433_P	439_A	2.193	1.00
451_A	454_T	2.192	1.00
188_E	192_N	2.175	1.00
65_E	77_D	2.150	1.00
301_A	305_D	2.141	1.00
191_L	198_H	2.133	1.00
449_R	456_R	2.116	1.00
256_M	356_A	2.116	1.00
99_T	125_I	2.102	1.00
296_Q	322_P	2.095	1.00
64_C	76_C	2.093	1.00
426_T	429_K	2.089	1.00
73_C	76_C	2.087	1.00
101_V	132_S	2.086	1.00
450_L	456_R	2.055	1.00
60_K	83_E	1.997	1.00
99_T	103_D	1.961	1.00
33_S	71_T	1.925	1.00
99_T	112_Q	1.920	1.00
100_K	111_V	1.919	1.00
114_A	149_H	1.912	1.00
381_T	384_M	1.900	1.00
64_C	73_C	1.891	1.00
546_E	555_H	1.875	1.00
98_R	104_T	1.871	1.00
102_E	166_I	1.870	1.00
553_C	589_V	1.856	1.00
404_P	410_S	1.833	1.00
258_E	319_T	1.790	1.00
411_Q	415_A	1.787	1.00
311_L	315_E	1.761	0.99
80_R	84_Q	1.749	0.99
22_E	182_Q	1.739	0.99
412_V	416_R	1.731	0.99
484_V	490_V	1.728	0.99
93_I	121_K	1.725	0.99
261_G	357_L	1.712	0.99
90_L	124_L	1.707	0.99
91_I	123_Y	1.700	0.99
442_V	446_A	1.699	0.99
16_A	29_A	1.676	0.99
427_K	433_P	1.665	0.99
448_E	451_A	1.662	0.99
459_A	467_E	1.658	0.99
190_I	218_L	1.653	0.99
186_Q	214_L	1.636	0.99
124_L	153_L	1.624	0.99
408_T	465_A	1.623	0.99
18_V	57_L	1.608	0.99
271_A	281_L	1.603	0.99
405_L	417_Q	1.603	0.99
550_N	585_E	1.600	0.99
77_D	80_R	1.596	0.99
403_V	417_Q	1.582	0.99
522_P	525_A	1.571	0.99
233_S	236_A	1.565	0.99
462_V	466_L	1.548	0.99
473_K	479_K	1.543	0.99
368_P	375_F	1.530	0.98
7_A	49_V	1.528	0.98
315_E	319_T	1.526	0.98
100_K	104_T	1.525	0.98
569_Q	586_L	1.521	0.98
401_P	411_Q	1.517	0.98
326_Q	330_Q	1.516	0.98
434_A	441_P	1.505	0.98
177_A	211_E	1.497	0.98
394_Q	399_Q	1.489	0.98
56_R	186_Q	1.488	0.98
548_S	551_A	1.479	0.98
18_V	44_S	1.470	0.98
477_R	481_T	1.461	0.98
452_S	455_D	1.454	0.98
93_I	110_N	1.448	0.98
480_A	486_Q	1.435	0.98
495_K	499_K	1.435	0.98
476_Y	479_K	1.434	0.98
425_A	429_K	1.428	0.98
450_L	454_T	1.425	0.98
436_A	442_V	1.423	0.98
286_L	332_L	1.416	0.97
196_I	225_I	1.409	0.97
551_A	585_E	1.404	0.97
9_K	13_Q	1.403	0.97
327_L	359_F	1.396	0.97
426_T	431_S	1.391	0.97
328_Y	356_A	1.386	0.97
16_A	71_T	1.384	0.97
101_V	104_T	1.380	0.97
373_Q	376_A	1.367	0.97
103_D	132_S	1.365	0.97
44_S	174_H	1.360	0.97
469_A	472_K	1.355	0.97
198_H	203_L	1.355	0.97
62_L	151_K	1.353	0.97
448_E	454_T	1.351	0.97
254_E	258_E	1.341	0.96
214_L	217_A	1.341	0.96
422_V	434_A	1.340	0.96
406_P	414_A	1.339	0.96
451_A	457_V	1.333	0.96
473_K	476_Y	1.331	0.96
13_Q	84_Q	1.331	0.96
433_P	437_T	1.325	0.96
98_R	111_V	1.316	0.96
72_P	76_C	1.313	0.96
395_S	401_P	1.309	0.96
443_N	463_P	1.299	0.96
396_A	402_T	1.299	0.96
19_V	186_Q	1.289	0.96
569_Q	573_A	1.289	0.96
467_E	471_A	1.280	0.95
394_Q	398_Q	1.278	0.95
14_T	17_D	1.276	0.95
400_A	414_A	1.275	0.95
334_I	338_E	1.275	0.95
427_K	436_A	1.273	0.95
13_Q	17_D	1.270	0.95
455_D	460_R	1.264	0.95
183_I	207_A	1.263	0.95
221_T	313_M	1.261	0.95
434_A	439_A	1.261	0.95
495_K	500_A	1.260	0.95
407_E	410_S	1.259	0.95
105_R	350_E	1.258	0.95
9_K	61_G	1.250	0.95
100_K	135_S	1.249	0.95
404_P	409_T	1.237	0.94
106_D	110_N	1.235	0.94
24_V	213_S	1.234	0.94
61_G	84_Q	1.233	0.94
425_A	482_T	1.231	0.94
427_K	434_A	1.229	0.94
433_P	443_N	1.229	0.94
256_M	328_Y	1.224	0.94
386_P	396_A	1.223	0.94
134_H	166_I	1.222	0.94
93_I	150_V	1.220	0.94
254_E	319_T	1.219	0.94
269_N	273_A	1.216	0.94
467_E	472_K	1.211	0.94
453_V	457_V	1.203	0.94
38_H	171_L	1.198	0.93
181_E	185_H	1.198	0.93
421_R	427_K	1.197	0.93
409_T	413_L	1.197	0.93
467_E	493_T	1.193	0.93
476_Y	484_V	1.190	0.93
49_V	56_R	1.189	0.93
389_V	394_Q	1.186	0.93
160_Q	352_T	1.185	0.93
124_L	135_S	1.183	0.93
477_R	508_E	1.180	0.93
139_L	350_E	1.180	0.93
228_G	231_Q	1.179	0.93
452_S	458_Q	1.176	0.93
423_Q	431_S	1.171	0.93
27_A	38_H	1.170	0.93
408_T	414_A	1.166	0.92
573_A	585_E	1.165	0.92
440_R	443_N	1.165	0.92
521_D	525_A	1.164	0.92
400_A	444_N	1.160	0.92
25_L	54_I	1.160	0.92
573_A	583_T	1.155	0.92
536_V	561_R	1.153	0.92
429_K	438_R	1.147	0.92
454_T	459_A	1.145	0.92
482_T	485_M	1.140	0.92
468_K	471_A	1.140	0.92
276_I	346_R	1.136	0.91
76_C	79_C	1.131	0.91
487_Q	499_K	1.129	0.91
245_D	276_I	1.128	0.91
475_A	478_W	1.128	0.91
490_V	496_A	1.123	0.91
451_A	455_D	1.122	0.91
90_L	110_N	1.118	0.91
121_K	151_K	1.114	0.91
477_R	480_A	1.113	0.91
500_A	503_H	1.113	0.91
385_T	393_P	1.110	0.90
405_L	419_L	1.109	0.90
111_V	135_S	1.107	0.90
403_V	435_A	1.107	0.90
292_I	325_I	1.106	0.90
192_N	198_H	1.106	0.90
372_R	375_F	1.102	0.90
175_L	290_H	1.099	0.90
429_K	432_E	1.099	0.90
455_D	458_Q	1.098	0.90
517_A	520_R	1.091	0.90
120_F	151_K	1.086	0.89
574_E	578_M	1.083	0.89
99_T	106_D	1.082	0.89
121_K	203_L	1.082	0.89
392_Q	404_P	1.082	0.89
460_R	472_K	1.080	0.89
196_I	228_G	1.079	0.89
430_K	436_A	1.076	0.89
477_R	482_T	1.074	0.89
253_V	289_L	1.074	0.89
369_E	373_Q	1.070	0.89
277_E	350_E	1.069	0.89
416_R	421_R	1.067	0.89
485_M	492_A	1.065	0.89
458_Q	461_P	1.064	0.88
430_K	439_A	1.062	0.88
26_T	236_A	1.061	0.88
93_I	153_L	1.060	0.88
368_P	371_P	1.058	0.88
474_E	477_R	1.054	0.88
410_S	416_R	1.053	0.88
232_V	356_A	1.051	0.88
433_P	497_L	1.044	0.88
124_L	162_L	1.044	0.88
417_Q	421_R	1.041	0.87
500_A	505_K	1.040	0.87
490_V	494_P	1.037	0.87
420_Q	496_A	1.034	0.87
408_T	412_V	1.030	0.87
455_D	459_A	1.029	0.87
472_K	476_Y	1.029	0.87
405_L	408_T	1.028	0.87
386_P	496_A	1.028	0.87
90_L	105_R	1.027	0.87
534_K	565_N	1.027	0.87
405_L	432_E	1.023	0.86
55_A	124_L	1.023	0.86
486_Q	492_A	1.021	0.86
128_V	160_Q	1.020	0.86
142_T	202_A	1.015	0.86
97_S	130_M	1.008	0.86
405_L	413_L	1.008	0.86
388_Q	467_E	1.002	0.85
68_I	120_F	0.999	0.85
384_M	388_Q	0.997	0.85
385_T	388_Q	0.992	0.85
467_E	470_P	0.992	0.85
99_T	105_R	0.992	0.85
471_A	475_A	0.989	0.85
406_P	412_V	0.988	0.84
7_A	56_R	0.988	0.84
435_A	439_A	0.985	0.84
512_K	516_E	0.983	0.84
8_R	15_F	0.981	0.84
437_T	443_N	0.980	0.84
426_T	430_K	0.978	0.84
57_L	356_A	0.977	0.84
143_L	154_L	0.976	0.84
416_R	423_Q	0.970	0.83
426_T	436_A	0.970	0.83
64_C	79_C	0.966	0.83
135_S	162_L	0.965	0.83
5_V	8_R	0.964	0.83
456_R	461_P	0.962	0.83
429_K	477_R	0.961	0.83
407_E	413_L	0.960	0.83
199_E	202_A	0.958	0.83
424_G	438_R	0.958	0.83
11_R	15_F	0.956	0.82
87_F	118_G	0.955	0.82
414_A	422_V	0.954	0.82
428_A	440_R	0.951	0.82
104_T	162_L	0.950	0.82
536_V	568_A	0.948	0.82
458_Q	470_P	0.948	0.82
302_L	305_D	0.948	0.82
570_Q	574_E	0.947	0.82
77_D	117_R	0.945	0.82
432_E	435_A	0.945	0.82
224_A	240_M	0.943	0.82
387_T	402_T	0.943	0.82
402_T	468_K	0.940	0.81
416_R	437_T	0.936	0.81
409_T	415_A	0.935	0.81
438_R	444_N	0.933	0.81
30_N	123_Y	0.932	0.81
391_P	394_Q	0.930	0.81
570_Q	573_A	0.930	0.81
292_I	313_M	0.928	0.81
456_R	459_A	0.928	0.81
409_T	479_K	0.928	0.81
93_I	104_T	0.927	0.80
38_H	191_L	0.927	0.80
27_A	172_Q	0.926	0.80
397_P	459_A	0.925	0.80
438_R	450_L	0.925	0.80
10_W	278_W	0.925	0.80
413_L	418_Q	0.923	0.80
476_Y	480_A	0.923	0.80
6_L	15_F	0.922	0.80
428_A	434_A	0.921	0.80
418_Q	429_K	0.917	0.80
103_D	241_L	0.915	0.80
406_P	409_T	0.914	0.80
424_G	427_K	0.914	0.80
383_V	428_A	0.912	0.79
412_V	419_L	0.912	0.79
13_Q	19_V	0.912	0.79
44_S	116_A	0.909	0.79
416_R	419_L	0.906	0.79
536_V	567_G	0.906	0.79
411_Q	417_Q	0.905	0.79
425_A	428_A	0.903	0.79
93_I	123_Y	0.901	0.79
383_V	391_P	0.898	0.78
121_K	142_T	0.896	0.78
478_W	490_V	0.896	0.78
536_V	539_V	0.895	0.78
459_A	491_V	0.895	0.78
394_Q	421_R	0.893	0.78
416_R	428_A	0.892	0.78
458_Q	463_P	0.892	0.78
573_A	586_L	0.891	0.78
433_P	438_R	0.889	0.78
523_W	530_L	0.889	0.78
466_L	469_A	0.889	0.78
90_L	93_I	0.888	0.78
466_L	478_W	0.887	0.77
500_A	506_T	0.885	0.77
442_V	457_V	0.884	0.77
57_L	61_G	0.884	0.77
49_V	213_S	0.884	0.77
414_A	426_T	0.882	0.77
471_A	479_K	0.879	0.77
257_V	320_I	0.877	0.77
456_R	470_P	0.877	0.77
185_H	188_E	0.876	0.77
460_R	466_L	0.874	0.76
30_N	132_S	0.873	0.76
44_S	172_Q	0.873	0.76
435_A	465_A	0.872	0.76
186_Q	282_L	0.870	0.76
474_E	479_K	0.869	0.76
417_Q	424_G	0.869	0.76
414_A	479_K	0.868	0.76
392_Q	399_Q	0.867	0.76
400_A	409_T	0.865	0.76
446_A	449_R	0.865	0.76
552_V	586_L	0.863	0.75
151_K	164_V	0.863	0.75
572_L	588_I	0.863	0.75
502_E	506_T	0.861	0.75
442_V	445_A	0.861	0.75
25_L	346_R	0.860	0.75
466_L	474_E	0.859	0.75
435_A	444_N	0.857	0.75
440_R	445_A	0.856	0.75
576_L	584_V	0.856	0.75
454_T	457_V	0.855	0.75
469_A	499_K	0.854	0.75
448_E	453_V	0.853	0.75
171_L	329_Y	0.851	0.74
525_A	579_L	0.849	0.74
436_A	455_D	0.849	0.74
430_K	433_P	0.849	0.74
69_T	119_R	0.847	0.74
394_Q	446_A	0.847	0.74
518_I	522_P	0.845	0.74
402_T	461_P	0.842	0.74
444_N	471_A	0.842	0.74
228_G	232_V	0.842	0.74
442_V	448_E	0.842	0.74
491_V	502_E	0.841	0.74
249_A	281_L	0.841	0.74
406_P	453_V	0.838	0.73
175_L	351_M	0.837	0.73
427_K	452_S	0.837	0.73
290_H	350_E	0.836	0.73
98_R	124_L	0.835	0.73
449_R	455_D	0.835	0.73
428_A	436_A	0.834	0.73
425_A	437_T	0.832	0.73
90_L	99_T	0.832	0.73
407_E	440_R	0.829	0.73
438_R	446_A	0.829	0.73
49_V	172_Q	0.827	0.72
267_L	270_E	0.826	0.72
441_P	452_S	0.825	0.72
537_E	541_L	0.824	0.72
427_K	432_E	0.824	0.72
440_R	446_A	0.823	0.72
469_A	475_A	0.821	0.72
407_E	480_A	0.820	0.72
464_S	470_P	0.820	0.72
516_E	519_E	0.819	0.72
436_A	439_A	0.818	0.72
472_K	479_K	0.817	0.71
225_I	232_V	0.815	0.71
67_G	119_R	0.814	0.71
89_D	242_G	0.813	0.71
427_K	451_A	0.813	0.71
443_N	450_L	0.812	0.71
105_R	139_L	0.811	0.71
104_T	124_L	0.810	0.71
403_V	505_K	0.809	0.71
483_P	488_K	0.809	0.71
396_A	404_P	0.809	0.71
110_N	123_Y	0.807	0.70
432_E	445_A	0.806	0.70
109_D	294_M	0.806	0.70
433_P	453_V	0.805	0.70
55_A	105_R	0.804	0.70
553_C	587_T	0.804	0.70
402_T	405_L	0.803	0.70
371_P	374_S	0.801	0.70
399_Q	404_P	0.800	0.70
400_A	410_S	0.799	0.70
398_Q	424_G	0.798	0.70
405_L	475_A	0.798	0.70
401_P	461_P	0.798	0.70
199_E	356_A	0.796	0.69
414_A	421_R	0.796	0.69
530_L	571_K	0.796	0.69
540_A	572_L	0.795	0.69
271_A	275_G	0.794	0.69
398_Q	406_P	0.793	0.69
398_Q	442_V	0.793	0.69
424_G	428_A	0.792	0.69
374_S	377_P	0.792	0.69
245_D	313_M	0.792	0.69
118_G	210_A	0.790	0.69
415_A	421_R	0.788	0.69
490_V	508_E	0.784	0.68
88_V	335_G	0.783	0.68
4_Q	88_V	0.782	0.68
104_T	132_S	0.782	0.68
44_S	275_G	0.781	0.68
105_R	124_L	0.779	0.68
395_S	408_T	0.779	0.68
511_A	514_A	0.779	0.68
396_A	468_K	0.778	0.68
446_A	456_R	0.778	0.68
125_I	299_P	0.778	0.68
99_T	104_T	0.777	0.68
459_A	471_A	0.777	0.68
99_T	107_L	0.775	0.67
362_R	367_E	0.775	0.67
421_R	441_P	0.774	0.67
411_Q	425_A	0.773	0.67
37_I	186_Q	0.772	0.67
431_S	437_T	0.771	0.67
505_K	509_L	0.770	0.67
29_A	61_G	0.770	0.67
439_A	465_A	0.769	0.67
434_A	440_R	0.768	0.67
390_P	394_Q	0.768	0.67
414_A	481_T	0.767	0.67
470_P	476_Y	0.764	0.66
423_Q	429_K	0.764	0.66
108_L	134_H	0.763	0.66
64_C	72_P	0.763	0.66
484_V	488_K	0.761	0.66
54_I	177_A	0.759	0.66
396_A	401_P	0.759	0.66
8_R	39_H	0.758	0.66
117_R	186_Q	0.757	0.66
417_Q	426_T	0.757	0.66
430_K	438_R	0.754	0.65
476_Y	498_K	0.753	0.65
438_R	441_P	0.752	0.65
446_A	463_P	0.751	0.65
10_W	194_E	0.751	0.65
449_R	452_S	0.750	0.65
465_A	468_K	0.750	0.65
484_V	487_Q	0.749	0.65
384_M	464_S	0.748	0.65
438_R	464_S	0.748	0.65
379_A	386_P	0.747	0.64
429_K	435_A	0.746	0.64
87_F	351_M	0.745	0.64
426_T	450_L	0.744	0.64
536_V	541_L	0.744	0.64
464_S	472_K	0.737	0.63
527_V	531_S	0.736	0.63
436_A	466_L	0.736	0.63
429_K	433_P	0.734	0.63
35_G	68_I	0.734	0.63
466_L	496_A	0.734	0.63
467_E	485_M	0.733	0.63
84_Q	186_Q	0.733	0.63
479_K	482_T	0.732	0.63
453_V	461_P	0.731	0.63
150_V	182_Q	0.730	0.63
396_A	399_Q	0.727	0.62
399_Q	465_A	0.726	0.62
408_T	413_L	0.726	0.62
418_Q	432_E	0.726	0.62
442_V	481_T	0.725	0.62
413_L	417_Q	0.725	0.62
192_N	195_H	0.725	0.62
9_K	282_L	0.724	0.62
416_R	489_E	0.723	0.62
272_A	356_A	0.723	0.62
402_T	473_K	0.723	0.62
170_C	237_V	0.721	0.62
388_Q	502_E	0.721	0.62
466_L	470_P	0.720	0.62
445_A	457_V	0.720	0.62
504_E	510_A	0.720	0.62
420_Q	424_G	0.718	0.61
461_P	466_L	0.718	0.61
393_P	400_A	0.718	0.61
456_R	460_R	0.718	0.61
12_P	15_F	0.717	0.61
288_L	316_L	0.717	0.61
573_A	582_S	0.716	0.61
527_V	556_L	0.716	0.61
123_Y	132_S	0.715	0.61
272_A	278_W	0.714	0.61
210_A	217_A	0.713	0.61
416_R	427_K	0.712	0.61
8_R	218_L	0.710	0.61
383_V	431_S	0.709	0.60
268_I	346_R	0.708	0.60
475_A	488_K	0.708	0.60
457_V	463_P	0.707	0.60
142_T	150_V	0.707	0.60
414_A	417_Q	0.705	0.60
388_Q	496_A	0.703	0.60
488_K	494_P	0.702	0.60
9_K	194_E	0.702	0.60
120_F	149_H	0.702	0.60
392_Q	412_V	0.699	0.59
475_A	481_T	0.699	0.59
61_G	67_G	0.698	0.59
573_A	577_S	0.697	0.59
409_T	427_K	0.697	0.59
460_R	463_P	0.696	0.59
420_Q	469_A	0.695	0.59
451_A	472_K	0.693	0.59
453_V	456_R	0.693	0.59
428_A	433_P	0.693	0.59
450_L	455_D	0.692	0.59
370_V	375_F	0.691	0.58
139_L	345_R	0.690	0.58
468_K	472_K	0.689	0.58
291_R	294_M	0.689	0.58
445_A	449_R	0.689	0.58
464_S	467_E	0.688	0.58
430_K	448_E	0.687	0.58
441_P	502_E	0.685	0.58
27_A	171_L	0.684	0.58
449_R	460_R	0.683	0.58
415_A	420_Q	0.683	0.58
260_N	266_A	0.683	0.58
468_K	473_K	0.681	0.57
410_S	442_V	0.681	0.57
198_H	202_A	0.680	0.57
244_L	284_E	0.679	0.57
53_S	57_L	0.679	0.57
479_K	485_M	0.677	0.57
480_A	497_L	0.676	0.57
424_G	429_K	0.675	0.57
67_G	70_A	0.673	0.56
153_L	183_I	0.672	0.56
498_K	507_P	0.671	0.56
514_A	518_I	0.670	0.56
46_T	54_I	0.670	0.56
420_Q	439_A	0.669	0.56
32_L	159_P	0.669	0.56
46_T	49_V	0.668	0.56
434_A	466_L	0.666	0.56
419_L	430_K	0.665	0.56
60_K	352_T	0.665	0.56
566_R	580_K	0.664	0.55
379_A	448_E	0.664	0.55
441_P	493_T	0.663	0.55
396_A	406_P	0.663	0.55
400_A	428_A	0.663	0.55
95_A	209_A	0.662	0.55
324_D	328_Y	0.662	0.55
405_L	418_Q	0.661	0.55
368_P	376_A	0.661	0.55
494_P	500_A	0.660	0.55
446_A	459_A	0.656	0.55
426_T	438_R	0.655	0.54
232_V	300_A	0.654	0.54
435_A	489_E	0.654	0.54
474_E	483_P	0.654	0.54
118_G	190_I	0.653	0.54
153_L	162_L	0.652	0.54
379_A	384_M	0.652	0.54
73_C	79_C	0.652	0.54
114_A	186_Q	0.652	0.54
476_Y	509_L	0.649	0.54
467_E	487_Q	0.648	0.54
444_N	454_T	0.648	0.54
414_A	419_L	0.647	0.54
441_P	445_A	0.646	0.53
419_L	429_K	0.646	0.53
426_T	435_A	0.646	0.53
438_R	442_V	0.645	0.53
109_D	121_K	0.645	0.53
395_S	458_Q	0.644	0.53
53_S	61_G	0.644	0.53
426_T	437_T	0.644	0.53
163_P	333_L	0.644	0.53
437_T	440_R	0.643	0.53
61_G	186_Q	0.643	0.53
472_K	475_A	0.642	0.53
154_L	176_K	0.641	0.53
384_M	434_A	0.641	0.53
381_T	437_T	0.640	0.53
434_A	437_T	0.639	0.53
53_S	186_Q	0.638	0.53
416_R	420_Q	0.638	0.53
457_V	460_R	0.638	0.53
464_S	476_Y	0.637	0.52
55_A	139_L	0.637	0.52
9_K	84_Q	0.636	0.52
451_A	466_L	0.636	0.52
398_Q	493_T	0.636	0.52
483_P	486_Q	0.635	0.52
450_L	457_V	0.633	0.52
13_Q	83_E	0.631	0.52
394_Q	460_R	0.630	0.52
400_A	421_R	0.630	0.52
27_A	329_Y	0.629	0.52
93_I	227_S	0.628	0.51
430_K	453_V	0.627	0.51
406_P	413_L	0.626	0.51
482_T	498_K	0.626	0.51
386_P	392_Q	0.626	0.51
55_A	177_A	0.625	0.51
409_T	421_R	0.624	0.51
410_S	489_E	0.624	0.51
424_G	433_P	0.624	0.51
178_L	217_A	0.623	0.51
463_P	471_A	0.623	0.51
249_A	288_L	0.623	0.51
439_A	445_A	0.622	0.51
388_Q	393_P	0.622	0.51
463_P	486_Q	0.622	0.51
184_R	204_Q	0.622	0.51
268_I	281_L	0.622	0.51
391_P	461_P	0.620	0.50
111_V	123_Y	0.619	0.50
418_Q	422_V	0.619	0.50
393_P	487_Q	0.618	0.50
430_K	434_A	0.617	0.50
423_Q	427_K	0.617	0.50
401_P	409_T	0.617	0.50
398_Q	404_P	0.616	0.50
27_A	46_T	0.615	0.50
409_T	443_N	0.614	0.50
282_L	348_G	0.614	0.50
383_V	461_P	0.614	0.50
452_S	456_R	0.612	0.50
419_L	443_N	0.612	0.50
389_V	411_Q	0.612	0.50
425_A	431_S	0.612	0.50
469_A	492_A	0.610	0.49
422_V	428_A	0.610	0.49
142_T	207_A	0.610	0.49
388_Q	457_V	0.610	0.49
55_A	90_L	0.610	0.49
433_P	510_A	0.609	0.49
9_K	178_L	0.608	0.49
388_Q	443_N	0.607	0.49
382_A	460_R	0.606	0.49
53_S	190_I	0.605	0.49
209_A	213_S	0.605	0.49
207_A	294_M	0.604	0.49
166_I	350_E	0.604	0.49
475_A	491_V	0.603	0.49
371_P	377_P	0.602	0.48
431_S	439_A	0.602	0.48
389_V	392_Q	0.602	0.48
392_Q	496_A	0.598	0.48
418_Q	424_G	0.598	0.48
117_R	123_Y	0.598	0.48
471_A	481_T	0.598	0.48
398_Q	488_K	0.593	0.47
390_P	407_E	0.589	0.47
433_P	444_N	0.589	0.47
13_Q	256_M	0.589	0.47
467_E	488_K	0.588	0.47
395_S	422_V	0.588	0.47
423_Q	475_A	0.587	0.47
417_Q	440_R	0.587	0.47
453_V	503_H	0.587	0.47
380_P	495_K	0.587	0.47
473_K	478_W	0.586	0.47
23_H	358_A	0.586	0.47
412_V	445_A	0.584	0.46
441_P	444_N	0.584	0.46
494_P	498_K	0.584	0.46
46_T	175_L	0.583	0.46
77_D	81_E	0.583	0.46
61_G	91_I	0.583	0.46
406_P	441_P	0.583	0.46
439_A	443_N	0.582	0.46
331_T	334_I	0.580	0.46
470_P	474_E	0.580	0.46
473_K	483_P	0.579	0.46
410_S	413_L	0.579	0.46
422_V	427_K	0.579	0.46
435_A	445_A	0.577	0.46
397_P	472_K	0.577	0.46
459_A	487_Q	0.576	0.46
395_S	398_Q	0.575	0.45
587_T	590_E	0.574	0.45
205_L	320_I	0.574	0.45
208_R	248_Q	0.571	0.45
557_R	591_D	0.571	0.45
481_T	487_Q	0.571	0.45
245_D	348_G	0.569	0.45
438_R	449_R	0.569	0.45
190_I	330_Q	0.569	0.45
98_R	162_L	0.569	0.45
423_Q	481_T	0.569	0.45
508_E	512_K	0.568	0.45
472_K	477_R	0.568	0.45
417_Q	445_A	0.568	0.45
408_T	433_P	0.567	0.44
546_E	553_C	0.566	0.44
183_I	186_Q	0.566	0.44
63_N	219_S	0.566	0.44
402_T	412_V	0.566	0.44
477_R	483_P	0.564	0.44
38_H	296_Q	0.564	0.44
486_Q	498_K	0.563	0.44
424_G	484_V	0.563	0.44
401_P	407_E	0.563	0.44
55_A	132_S	0.562	0.44
394_Q	420_Q	0.562	0.44
409_T	472_K	0.561	0.44
372_R	377_P	0.561	0.44
234_T	250_L	0.560	0.44
436_A	504_E	0.560	0.44
403_V	459_A	0.560	0.44
445_A	467_E	0.560	0.44
583_T	587_T	0.559	0.44
25_L	292_I	0.558	0.43
452_S	477_R	0.558	0.43
402_T	444_N	0.557	0.43
442_V	452_S	0.557	0.43
451_A	458_Q	0.556	0.43
426_T	434_A	0.556	0.43
416_R	461_P	0.555	0.43
416_R	433_P	0.555	0.43
414_A	420_Q	0.554	0.43
106_D	139_L	0.554	0.43
258_E	318_R	0.553	0.43
380_P	429_K	0.553	0.43
387_T	401_P	0.553	0.43
433_P	440_R	0.552	0.43
396_A	510_A	0.552	0.43
412_V	457_V	0.552	0.43
172_Q	213_S	0.551	0.43
123_Y	207_A	0.551	0.43
393_P	396_A	0.551	0.43
417_Q	432_E	0.551	0.43
104_T	351_M	0.550	0.43
417_Q	423_Q	0.547	0.42
443_N	471_A	0.546	0.42
370_V	374_S	0.546	0.42
415_A	499_K	0.544	0.42
452_S	460_R	0.544	0.42
399_Q	454_T	0.543	0.42
98_R	103_D	0.540	0.41
445_A	455_D	0.540	0.41
422_V	430_K	0.540	0.41
397_P	410_S	0.540	0.41
440_R	454_T	0.539	0.41
488_K	500_A	0.539	0.41
109_D	209_A	0.538	0.41
99_T	124_L	0.538	0.41
179_D	182_Q	0.538	0.41
411_Q	429_K	0.537	0.41
492_A	513_L	0.536	0.41
277_E	345_R	0.535	0.41
8_R	23_H	0.535	0.41
394_Q	440_R	0.535	0.41
473_K	490_V	0.535	0.41
539_V	542_N	0.534	0.41
475_A	498_K	0.533	0.41
412_V	417_Q	0.533	0.41
445_A	461_P	0.532	0.41
431_S	435_A	0.532	0.41
81_E	233_S	0.532	0.41
465_A	476_Y	0.531	0.40
421_R	431_S	0.530	0.40
411_Q	438_R	0.527	0.40
22_E	185_H	0.527	0.40
414_A	485_M	0.527	0.40
428_A	470_P	0.525	0.40
209_A	224_A	0.525	0.40
400_A	446_A	0.525	0.40
438_R	480_A	0.525	0.40
371_P	378_V	0.524	0.40
544_W	555_H	0.524	0.40
277_E	346_R	0.524	0.40
453_V	471_A	0.523	0.40
401_P	472_K	0.523	0.40
422_V	477_R	0.522	0.40
567_G	584_V	0.522	0.40
455_D	484_V	0.522	0.40
178_L	186_Q	0.522	0.40
415_A	427_K	0.522	0.40
498_K	505_K	0.521	0.39
388_Q	392_Q	0.521	0.39
393_P	474_E	0.520	0.39
430_K	476_Y	0.520	0.39
90_L	135_S	0.519	0.39
66_T	69_T	0.518	0.39
389_V	456_R	0.518	0.39
418_Q	468_K	0.517	0.39
413_L	421_R	0.517	0.39
410_S	420_Q	0.517	0.39
460_R	487_Q	0.516	0.39
214_L	243_T	0.515	0.39
105_R	110_N	0.515	0.39
334_I	337_K	0.514	0.39
544_W	547_E	0.514	0.39
435_A	475_A	0.514	0.39
424_G	441_P	0.513	0.39
382_A	404_P	0.513	0.39
462_V	479_K	0.513	0.39
430_K	465_A	0.513	0.39
461_P	467_E	0.512	0.38
385_T	441_P	0.510	0.38
110_N	118_G	0.510	0.38
464_S	474_E	0.509	0.38
468_K	485_M	0.508	0.38
49_V	276_I	0.508	0.38
460_R	480_A	0.507	0.38
416_R	474_E	0.507	0.38
172_Q	210_A	0.506	0.38
178_L	351_M	0.506	0.38
44_S	265_M	0.505	0.38
400_A	452_S	0.503	0.37
81_E	84_Q	0.502	0.37
470_P	473_K	0.502	0.37
30_N	33_S	0.502	0.37
14_T	341_Y	0.502	0.37
410_S	444_N	0.501	0.37
121_K	186_Q	0.500	0.37
442_V	449_R	0.500	0.37

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1jr3A	3	0.5692	100	0.649	Contact Map
1sxjC	1	0.4883	100	0.702	Contact Map
1sxjD	1	0.4837	100	0.71	Contact Map
1iqpA	5	0.4899	100	0.712	Contact Map
2chqA	3	0.4821	100	0.714	Contact Map
1a5tA	2	0.4961	100	0.715	Contact Map
1sxjE	1	0.4759	100	0.717	Contact Map
1jr3D	1	0.4977	100	0.734	Contact Map
3zh9B	1	0.4883	100	0.741	Contact Map
3u61B	3	0.4728	100	0.752	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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