GREMLIN Database
BTUB - Vitamin B12 transporter BtuB
UniProt: P06129 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG10126
Length: 614 (554)
Sequences: 52351 (42898)
Seq/√Len: 1822.5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
501_Y521_Q3.9121.00
540_Y565_S3.8161.00
184_T228_H3.7251.00
457_R482_K3.4191.00
377_A389_G3.4131.00
403_Y442_F3.3891.00
409_Y436_K3.3361.00
582_R609_S3.3111.00
411_T436_K3.1891.00
535_D572_A3.1621.00
234_W278_G3.1591.00
192_Y220_K3.0641.00
379_S389_G3.0621.00
329_G364_G2.9681.00
162_A172_Y2.7711.00
498_T526_Q2.7001.00
190_G220_K2.6441.00
403_Y444_G2.6371.00
237_F275_R2.5831.00
457_R480_R2.4711.00
371_F397_W2.4251.00
51_R55_D2.3811.00
449_V490_F2.3651.00
126_R150_I2.3441.00
567_W589_F2.3331.00
444_G451_W2.2891.00
334_G361_Y2.2801.00
184_T226_L2.2671.00
503_Y521_Q2.2581.00
178_Q186_V2.2561.00
585_I588_L2.2501.00
235_S277_N2.2331.00
584_K607_T2.2191.00
234_W276_Y2.2151.00
540_Y567_W2.1751.00
124_V149_I2.1731.00
542_Y565_S2.1651.00
233_A278_G2.1561.00
495_L527_L2.0861.00
185_R227_E2.0791.00
379_S387_R2.0721.00
450_N489_N2.0651.00
231_T234_W2.0611.00
50_T53_D2.0501.00
242_G270_W2.0271.00
194_H218_L2.0171.00
537_G570_A2.0131.00
538_I567_W2.0071.00
572_A580_T2.0031.00
399_F405_F1.9941.00
452_R487_T1.9711.00
580_T611_S1.9611.00
396_G404_R1.9311.00
240_G270_W1.9261.00
411_T434_K1.9181.00
339_K356_R1.8931.00
545_T560_K1.8811.00
335_V358_T1.8451.00
409_Y438_W1.8311.00
579_L612_Y1.8311.00
158_T176_T1.8021.00
574_P580_T1.7971.00
371_F395_A1.7851.00
399_F403_Y1.7841.00
244_D268_Q1.7761.00
188_L224_G1.7731.00
372_T398_E1.7711.00
61_S64_D1.7611.00
329_G366_Q1.7321.00
227_E235_S1.7211.00
100_I105_L1.7191.00
463_L479_A1.7181.00
496_T528_D1.7151.00
534_F573_Y1.7081.00
523_V542_Y1.7011.00
455_G482_K1.6851.00
466_Y473_Y1.6831.00
191_D221_T1.6731.00
539_T568_D1.6611.00
495_L529_W1.6441.00
437_Q458_N1.6431.00
451_W488_A1.6431.00
391_W411_T1.6311.00
579_L610_G1.6231.00
337_W358_T1.6211.00
436_K461_S1.6061.00
328_H369_G1.6051.00
459_D478_K1.6041.00
69_L129_Y1.5941.00
48_V128_E1.5941.00
459_D480_R1.5891.00
101_D225_A1.5831.00
227_E237_F1.5831.00
406_I441_A1.5821.00
236_G276_Y1.5731.00
494_P529_W1.5681.00
186_V226_L1.5671.00
583_G606_Y1.5621.00
125_Q152_T1.5601.00
186_V190_G1.5581.00
161_S611_S1.5521.00
281_I291_H1.5461.00
159_E613_T1.5441.00
456_Y504_V1.5431.00
497_H527_L1.5421.00
593_Y601_T1.5401.00
443_E452_R1.5271.00
240_G272_A1.5271.00
400_I403_Y1.5261.00
183_K228_H1.5251.00
330_S367_Q1.5201.00
453_I486_A1.5151.00
367_Q372_T1.5131.00
448_G490_F1.5121.00
575_V581_V1.5081.00
229_N235_S1.5041.00
339_K354_D1.5001.00
542_Y563_G1.4991.00
585_I606_Y1.4861.00
406_I443_E1.4791.00
52_Q56_R1.4711.00
431_D462_D1.4681.00
128_E148_N1.4571.00
100_I151_T1.4521.00
89_R485_E1.4431.00
281_I285_L1.4361.00
569_L588_L1.4291.00
359_G378_R1.4271.00
489_N498_T1.4241.00
405_F442_F1.4201.00
482_K505_D1.4191.00
526_Q539_T1.4171.00
391_W395_A1.4091.00
51_R152_T1.4091.00
497_H525_Y1.3971.00
456_Y483_G1.3921.00
281_I289_Y1.3921.00
372_T396_G1.3921.00
125_Q153_R1.3911.00
465_D476_E1.3871.00
88_I145_G1.3861.00
281_I288_S1.3831.00
449_V488_A1.3821.00
585_I604_R1.3741.00
394_S408_S1.3701.00
535_D574_P1.3701.00
185_R229_N1.3701.00
528_D537_G1.3681.00
434_K462_D1.3651.00
579_L583_G1.3561.00
439_E454_S1.3451.00
407_A438_W1.3391.00
192_Y218_L1.3371.00
53_D56_R1.3361.00
277_N284_Q1.3331.00
414_K433_E1.3301.00
71_G502_D1.3301.00
359_G380_D1.3291.00
57_W68_R1.3251.00
453_I484_V1.3241.00
188_L222_L1.3221.00
101_D151_T1.3211.00
330_S365_L1.3111.00
285_L318_V1.3061.00
363_T374_E1.3011.00
581_V610_G1.2981.00
541_Q568_D1.2881.00
120_P123_L1.2851.00
156_P185_R1.2821.00
570_A582_R1.2811.00
161_S173_D1.2811.00
52_Q55_D1.2801.00
534_F571_V1.2781.00
323_N330_S1.2761.00
375_G393_T1.2751.00
238_V272_A1.2651.00
536_W571_V1.2631.00
153_R227_E1.2611.00
336_D359_G1.2581.00
287_T318_V1.2551.00
586_A605_E1.2511.00
175_S187_T1.2511.00
496_T530_Q1.2501.00
190_G222_L1.2491.00
373_F395_A1.2481.00
153_R225_A1.2461.00
500_S524_K1.2421.00
491_D496_T1.2421.00
406_I454_S1.2401.00
186_V224_G1.2361.00
535_D580_T1.2321.00
101_D239_R1.2311.00
380_D390_T1.2221.00
499_V525_Y1.2201.00
568_D586_A1.2151.00
329_G334_G1.2131.00
608_L612_Y1.2121.00
403_Y407_A1.2081.00
242_G268_Q1.2041.00
521_Q544_G1.2001.00
230_F236_G1.1961.00
455_G484_V1.1941.00
163_G609_S1.1931.00
235_S279_E1.1881.00
64_D67_R1.1871.00
236_G274_L1.1861.00
89_R439_E1.1861.00
440_G455_G1.1861.00
580_T613_T1.1851.00
38_P41_T1.1841.00
365_L374_E1.1831.00
158_T162_A1.1821.00
281_I290_S1.1771.00
317_T336_D1.1741.00
187_T225_A1.1711.00
572_A582_R1.1711.00
575_V579_L1.1681.00
438_W459_D1.1651.00
291_H314_K1.1561.00
47_T131_R1.1541.00
163_G171_N1.1541.00
222_L242_G1.1491.00
502_D522_Q1.1381.00
164_W172_Y1.1351.00
270_W274_L1.1341.00
451_W486_A1.1311.00
15_A18_A1.1301.00
233_A279_E1.1301.00
543_L546_R1.1261.00
189_L223_Y1.1231.00
239_R273_G1.1221.00
438_W457_R1.1211.00
288_S317_T1.1201.00
337_W356_R1.1181.00
70_P487_T1.1161.00
367_Q370_D1.1051.00
567_W591_K1.1031.00
131_R485_E1.1011.00
72_V88_I1.0981.00
285_L289_Y1.0951.00
412_S435_S1.0911.00
538_I569_L1.0901.00
583_G608_L1.0801.00
395_A399_F1.0741.00
484_V503_Y1.0701.00
358_T381_D1.0671.00
489_N496_T1.0671.00
407_A440_G1.0651.00
164_W170_Q1.0641.00
73_D522_Q1.0631.00
461_S478_K1.0631.00
237_F277_N1.0611.00
143_I435_S1.0591.00
289_Y314_K1.0561.00
41_T398_E1.0551.00
284_Q321_A1.0531.00
24_S27_T1.0511.00
335_V360_I1.0511.00
481_I506_A1.0501.00
497_H504_V1.0491.00
567_W588_L1.0481.00
365_L372_T1.0421.00
435_S458_N1.0371.00
374_E394_S1.0371.00
99_L104_R1.0361.00
360_I379_S1.0361.00
125_Q150_I1.0361.00
51_R125_Q1.0271.00
528_D535_D1.0251.00
97_L104_R1.0231.00
281_I286_I1.0211.00
530_Q535_D1.0161.00
331_I364_G1.0151.00
398_E401_E1.0151.00
414_K420_Q1.0141.00
508_N511_T1.0121.00
128_E150_I1.0081.00
441_A454_S1.0071.00
570_A584_K1.0061.00
541_Q566_L1.0051.00
405_F440_G1.0041.00
566_L593_Y1.0031.00
523_V544_G1.0031.00
514_P520_K1.0011.00
373_F393_T0.9981.00
398_E404_R0.9971.00
168_S196_H0.9961.00
236_G240_G0.9931.00
582_R611_S0.9931.00
25_P28_L0.9901.00
69_L72_V0.9901.00
490_F497_H0.9891.00
527_L538_I0.9881.00
285_L320_W0.9871.00
281_I287_T0.9851.00
285_L288_S0.9851.00
328_H366_Q0.9811.00
165_G169_Y0.9811.00
451_W455_G0.9761.00
317_T338_Q0.9761.00
287_T291_H0.9761.00
402_G444_G0.9741.00
503_Y520_K0.9741.00
170_Q194_H0.9731.00
531_L536_W0.9731.00
48_V126_R0.9701.00
399_F442_F0.9701.00
129_Y147_V0.9681.00
282_K285_L0.9681.00
543_L564_V0.9661.00
43_L394_S0.9601.00
216_G248_N0.9581.00
275_R286_I0.9571.00
494_P530_Q0.9571.00
238_V274_L0.9571.00
325_I330_S0.9561.00
99_L148_N0.9551.00
238_V242_G0.9521.00
229_N232_D0.9491.00
172_Y192_Y0.9461.00
442_F453_I0.9421.00
576_T579_L0.9421.00
120_P191_D0.9421.00
581_V608_L0.9421.00
162_A170_Q0.9421.00
123_L189_L0.9421.00
287_T316_Y0.9371.00
547_Y560_K0.9351.00
574_P613_T0.9351.00
230_F234_W0.9321.00
438_W442_F0.9301.00
571_V585_I0.9291.00
435_S460_V0.9281.00
276_Y280_L0.9281.00
453_I457_R0.9281.00
533_D573_Y0.9261.00
390_T413_Y0.9261.00
160_I164_W0.9261.00
366_Q375_G0.9251.00
578_H612_Y0.9241.00
376_A392_Q0.9241.00
225_A237_F0.9201.00
420_Q473_Y0.9191.00
448_G491_D0.9161.00
17_S20_A0.9151.00
404_R443_E0.9151.00
155_E185_R0.9121.00
456_Y485_E0.9121.00
244_D266_Y0.9111.00
123_L223_Y0.9091.00
123_L187_T0.9081.00
283_S322_N0.9031.00
581_V585_I0.9021.00
324_V331_I0.9021.00
183_K230_F0.8991.00
391_W409_Y0.8981.00
159_E611_S0.8981.00
25_P29_V0.8981.00
336_D361_Y0.8971.00
368_V373_F0.8961.00
56_R528_D0.8961.00
171_N191_D0.8941.00
588_L604_R0.8931.00
53_D68_R0.8921.00
333_A337_W0.8911.00
377_A391_W0.8901.00
560_K595_T0.8871.00
241_Y271_D0.8851.00
586_A607_T0.8851.00
479_A515_L0.8831.00
181_G184_T0.8831.00
86_I147_V0.8821.00
136_A376_A0.8811.00
164_W168_S0.8801.00
169_Y195_T0.8791.00
183_K229_N0.8771.00
122_A173_D0.8771.00
43_L396_G0.8761.00
171_N193_A0.8751.00
14_T18_A0.8741.00
153_R237_F0.8731.00
328_H367_Q0.8731.00
433_E460_V0.8721.00
98_V147_V0.8711.00
138_Y146_V0.8691.00
514_P547_Y0.8651.00
590_D603_G0.8651.00
159_E175_S0.8651.00
360_I364_G0.8631.00
417_N420_Q0.8621.00
333_A362_L0.8601.00
360_I381_D0.8601.00
47_T487_T0.8581.00
546_R561_M0.8571.00
566_L601_T0.8531.00
325_I328_H0.8521.00
501_Y523_V0.8511.00
14_T17_S0.8501.00
173_D191_D0.8501.00
70_P500_S0.8491.00
466_Y471_L0.8491.00
544_G563_G0.8471.00
18_A21_Q0.8471.00
104_R141_D0.8471.00
326_V331_I0.8461.00
62_V149_I0.8451.00
231_T278_G0.8441.00
33_N37_Q0.8431.00
288_S292_S0.8431.00
499_V523_V0.8421.00
277_N286_I0.8411.00
158_T164_W0.8391.00
318_V322_N0.8371.00
99_L146_V0.8331.00
322_N325_I0.8321.00
179_Q185_R0.8321.00
174_V178_Q0.8321.00
545_T563_G0.8311.00
486_A490_F0.8301.00
54_I65_V0.8281.00
157_G177_Q0.8251.00
222_L226_L0.8241.00
86_I98_V0.8231.00
395_A407_A0.8231.00
59_S65_V0.8211.00
68_R539_T0.8201.00
282_K322_N0.8201.00
71_G131_R0.8161.00
250_D261_D0.8141.00
287_T290_S0.8131.00
220_K224_G0.8111.00
332_G336_D0.8101.00
530_Q574_P0.8091.00
42_V46_T0.8091.00
224_G228_H0.8081.00
51_R54_I0.8081.00
49_V69_L0.8071.00
494_P497_H0.8061.00
332_G365_L0.8031.00
436_K459_D0.8021.00
523_V565_S0.8011.00
355_Q384_Q0.8011.00
194_H216_G0.8011.00
223_Y241_Y0.8011.00
74_I86_I0.7991.00
434_K461_S0.7981.00
504_V518_R0.7981.00
357_N415_A0.7971.00
445_L449_V0.7961.00
47_T69_L0.7941.00
374_E396_G0.7941.00
16_F19_W0.7931.00
484_V488_A0.7931.00
382_N386_G0.7911.00
193_A219_S0.7901.00
127_V149_I0.7901.00
433_E463_L0.7891.00
456_Y502_D0.7881.00
23_T26_D0.7861.00
45_P439_E0.7841.00
319_Q336_D0.7831.00
343_T352_G0.7831.00
188_L192_Y0.7831.00
89_R483_G0.7821.00
521_Q542_Y0.7811.00
286_I290_S0.7791.00
393_T409_Y0.7791.00
523_V527_L0.7781.00
565_S591_K0.7771.00
460_V463_L0.7761.00
445_L448_G0.7751.00
102_G148_N0.7731.00
46_T128_E0.7721.00
158_T186_V0.7711.00
526_Q537_G0.7701.00
172_Y176_T0.7671.00
88_I129_Y0.7671.00
21_Q24_S0.7671.00
449_V453_I0.7651.00
332_G363_T0.7641.00
281_I324_V0.7641.00
60_T64_D0.7631.00
536_W569_L0.7621.00
569_L585_I0.7611.00
154_D227_E0.7611.00
562_G591_K0.7601.00
184_T188_L0.7601.00
546_R562_G0.7591.00
363_T392_Q0.7591.00
175_S189_L0.7581.00
498_T528_D0.7571.00
319_Q361_Y0.7571.00
220_K244_D0.7541.00
282_K286_I0.7541.00
578_H613_T0.7531.00
282_K288_S0.7531.00
89_R456_Y0.7521.00
450_N491_D0.7511.00
334_G338_Q0.7511.00
324_V333_A0.7501.00
97_L146_V0.7471.00
121_I124_V0.7451.00
283_S320_W0.7441.00
497_H502_D0.7431.00
274_L278_G0.7431.00
56_R535_D0.7431.00
23_T28_L0.7421.00
246_R266_Y0.7401.00
529_W536_W0.7401.00
505_D520_K0.7401.00
590_D604_R0.7401.00
329_G333_A0.7401.00
388_H434_K0.7391.00
381_D385_F0.7381.00
323_N332_G0.7371.00
281_I322_N0.7361.00
362_L377_A0.7351.00
286_I321_A0.7341.00
291_H312_E0.7341.00
390_T411_T0.7321.00
286_I319_Q0.7311.00
187_T223_Y0.7301.00
161_S609_S0.7301.00
62_V65_V0.7291.00
480_R507_R0.7271.00
177_Q187_T0.7261.00
154_D185_R0.7261.00
577_S612_Y0.7261.00
141_D357_N0.7251.00
418_L421_L0.7251.00
488_A499_V0.7241.00
103_V288_S0.7231.00
284_Q287_T0.7231.00
31_T34_R0.7221.00
547_Y561_M0.7221.00
39_R48_V0.7221.00
497_H500_S0.7211.00
283_S287_T0.7191.00
97_L142_A0.7181.00
47_T70_P0.7181.00
341_T352_G0.7171.00
198_Y603_G0.7151.00
277_N282_K0.7151.00
67_R541_Q0.7141.00
341_T354_D0.7121.00
156_P182_D0.7111.00
179_Q182_D0.7101.00
458_N481_I0.7081.00
160_I174_V0.7051.00
155_E177_Q0.7041.00
331_I362_L0.7031.00
161_S164_W0.7031.00
574_P578_H0.7021.00
284_Q323_N0.7001.00
589_F592_D0.7001.00
95_H433_E0.7001.00
73_D519_A0.6991.00
584_K609_S0.6991.00
513_T547_Y0.6991.00
382_N385_F0.6981.00
447_A451_W0.6981.00
122_A161_S0.6981.00
316_Y320_W0.6971.00
520_K544_G0.6971.00
230_F276_Y0.6961.00
45_P454_S0.6941.00
392_Q408_S0.6941.00
446_T449_V0.6941.00
279_E284_Q0.6921.00
130_I146_V0.6921.00
281_I292_S0.6891.00
228_H231_T0.6881.00
417_N430_L0.6881.00
324_V327_G0.6861.00
87_F92_N0.6861.00
185_R235_S0.6841.00
285_L290_S0.6841.00
91_T144_G0.6831.00
292_S296_N0.6821.00
282_K324_V0.6821.00
487_T498_T0.6811.00
494_P531_L0.6811.00
55_D611_S0.6791.00
492_T495_L0.6761.00
391_W394_S0.6761.00
326_V329_G0.6731.00
440_G444_G0.6701.00
580_T583_G0.6701.00
535_D538_I0.6691.00
246_R264_K0.6671.00
602_A605_E0.6671.00
156_P229_N0.6661.00
283_S288_S0.6651.00
430_L464_I0.6641.00
329_G336_D0.6621.00
496_T499_V0.6591.00
219_S245_N0.6581.00
567_W585_I0.6581.00
381_D387_R0.6581.00
225_A239_R0.6571.00
98_V149_I0.6561.00
152_T175_S0.6551.00
23_T27_T0.6551.00
130_I138_Y0.6551.00
373_F377_A0.6541.00
184_T230_F0.6541.00
364_G375_G0.6531.00
355_Q415_A0.6521.00
368_V395_A0.6491.00
400_I444_G0.6461.00
525_Y565_S0.6451.00
280_L320_W0.6441.00
527_L531_L0.6431.00
282_K290_S0.6431.00
91_T460_V0.6431.00
417_N421_L0.6421.00
464_I473_Y0.6421.00
153_R239_R0.6391.00
372_T375_G0.6381.00
218_L246_R0.6381.00
318_V337_W0.6371.00
361_Y378_R0.6371.00
72_V86_I0.6361.00
132_G439_E0.6361.00
158_T174_V0.6341.00
133_P410_G0.6331.00
131_R487_T0.6331.00
313_M340_Q0.6331.00
174_V190_G0.6291.00
520_K545_T0.6291.00
217_F245_N0.6291.00
160_I176_T0.6271.00
169_Y193_A0.6271.00
363_T376_A0.6271.00
504_V522_Q0.6271.00
375_G379_S0.6271.00
398_E402_G0.6261.00
176_T179_Q0.6261.00
281_I284_Q0.6241.00
285_L292_S0.6241.00
272_A276_Y0.6231.00
245_N267_S0.6201.00
573_Y576_T0.6201.00
497_H501_Y0.6181.00
408_S439_E0.6181.00
533_D574_P0.6161.00
64_D586_A0.6151.00
464_I475_N0.6151.00
166_S606_Y0.6151.00
184_T224_G0.6141.00
317_T322_N0.6141.00
233_A280_L0.6141.00
450_N453_I0.6141.00
485_E502_D0.6131.00
37_Q41_T0.6131.00
289_Y316_Y0.6111.00
152_T159_E0.6101.00
279_E282_K0.6101.00
98_V116_L0.6091.00
491_D494_P0.6071.00
497_H503_Y0.6071.00
154_D187_T0.6061.00
282_K323_N0.6061.00
130_I134_R0.6051.00
163_G173_D0.6051.00
156_P179_Q0.6051.00
26_D29_V0.6031.00
322_N333_A0.6021.00
65_V121_I0.6021.00
330_S333_A0.6021.00
481_I504_V0.6011.00
317_T321_A0.5991.00
413_Y432_P0.5981.00
506_A518_R0.5981.00
406_I452_R0.5981.00
234_W238_V0.5981.00
194_H220_K0.5981.00
544_G565_S0.5971.00
338_Q357_N0.5971.00
87_F95_H0.5971.00
153_R235_S0.5961.00
393_T397_W0.5961.00
522_Q543_L0.5951.00
183_K231_T0.5941.00
495_L503_Y0.5941.00
332_G335_V0.5941.00
540_Y589_F0.5931.00
53_D57_W0.5931.00
133_P412_S0.5911.00
40_S398_E0.5911.00
227_E230_F0.5901.00
137_V332_G0.5901.00
322_N326_V0.5901.00
154_D186_V0.5881.00
460_V479_A0.5881.00
538_I588_L0.5881.00
367_Q398_E0.5871.00
339_K358_T0.5871.00
125_Q155_E0.5861.00
536_W540_Y0.5861.00
70_P131_R0.5861.00
288_S291_H0.5851.00
506_A515_L0.5851.00
275_R288_S0.5841.00
565_S589_F0.5841.00
486_A501_Y0.5841.00
290_S294_D0.5831.00
91_T95_H0.5821.00
331_I334_G0.5811.00
419_G422_Y0.5811.00
331_I335_V0.5811.00
269_S292_S0.5811.00
176_T186_V0.5791.00
88_I96_V0.5761.00
370_D401_E0.5751.00
608_L611_S0.5751.00
281_I293_K0.5741.00
319_Q334_G0.5741.00
442_F451_W0.5731.00
531_L534_F0.5731.00
509_A512_D0.5721.00
315_Q338_Q0.5711.00
75_T85_S0.5711.00
62_V124_V0.5701.00
91_T481_I0.5701.00
397_W400_I0.5691.00
575_V578_H0.5691.00
158_T161_S0.5681.00
508_N512_D0.5671.00
59_S64_D0.5671.00
495_L499_V0.5671.00
123_L221_T0.5671.00
122_A189_L0.5661.00
399_F402_G0.5651.00
463_L481_I0.5611.00
45_P131_R0.5611.00
534_F538_I0.5601.00
160_I163_G0.5601.00
282_K291_H0.5601.00
150_I153_R0.5601.00
571_V575_V0.5601.00
525_Y540_Y0.5591.00
340_Q355_Q0.5581.00
103_V273_G0.5571.00
56_R530_Q0.5571.00
293_K310_L0.5561.00
566_L590_D0.5561.00
43_L374_E0.5551.00
397_W402_G0.5551.00
480_R505_D0.5551.00
366_Q373_F0.5531.00
158_T178_Q0.5521.00
530_Q533_D0.5521.00
368_V371_F0.5511.00
290_S317_T0.5501.00
96_V144_G0.5491.00
606_Y610_G0.5481.00
165_G168_S0.5471.00
431_D434_K0.5471.00
490_F527_L0.5471.00
283_S286_I0.5461.00
366_Q369_G0.5441.00
438_W455_G0.5411.00
314_K317_T0.5391.00
487_T500_S0.5391.00
430_L475_N0.5391.00
336_D339_K0.5381.00
53_D498_T0.5371.00
413_Y434_K0.5371.00
183_K232_D0.5371.00
195_T217_F0.5351.00
40_S404_R0.5351.00
439_E485_E0.5351.00
436_K457_R0.5331.00
321_A332_G0.5321.00
425_Y472_K0.5321.00
569_L583_G0.5311.00
433_E462_D0.5301.00
136_A392_Q0.5301.00
516_L547_Y0.5301.00
196_H216_G0.5291.00
570_A607_T0.5281.00
272_A275_R0.5281.00
224_G240_G0.5271.00
167_N605_E0.5271.00
120_P171_N0.5271.00
412_S437_Q0.5261.00
282_K292_S0.5261.00
20_A23_T0.5261.00
43_L46_T0.5251.00
314_K318_V0.5251.00
283_S290_S0.5241.00
519_A543_L0.5241.00
224_G227_E0.5231.00
382_N415_A0.5231.00
115_D118_Q0.5231.00
462_D475_N0.5211.00
275_R278_G0.5201.00
371_F399_F0.5181.00
160_I612_Y0.5171.00
16_F20_A0.5171.00
392_Q410_G0.5171.00
91_T458_N0.5171.00
524_K539_T0.5161.00
293_K312_E0.5161.00
39_R46_T0.5141.00
151_T225_A0.5141.00
41_T367_Q0.5141.00
159_E162_A0.5141.00
393_T396_G0.5131.00
37_Q42_V0.5131.00
248_N264_K0.5111.00
24_S28_L0.5111.00
579_L608_L0.5101.00
41_T372_T0.5091.00
527_L536_W0.5081.00
223_Y239_R0.5081.00
234_W280_L0.5081.00
527_L540_Y0.5061.00
370_D397_W0.5051.00
329_G367_Q0.5051.00
513_T557_Q0.5051.00
130_I135_S0.5041.00
575_V610_G0.5031.00
490_F499_V0.5031.00
226_L238_V0.5031.00
44_A392_Q0.5021.00
463_L477_G0.5021.00
288_S296_N0.5021.00
67_R568_D0.5011.00
286_I289_Y0.5001.00
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2gufA 1 0.8974 100 0.155 Contact Map
2hdiA 1 0.8664 100 0.217 Contact Map
1kmoA 1 0.9365 100 0.226 Contact Map
1xkwA 1 0.9088 100 0.232 Contact Map
3v8xA 1 0.9251 100 0.233 Contact Map
3qlbA 1 0.8941 100 0.234 Contact Map
3efmA 1 0.8534 100 0.237 Contact Map
3fhhA 1 0.9104 100 0.238 Contact Map
4b7oA 1 0.9169 100 0.252 Contact Map
4cu4A 1 0.9316 100 0.252 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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