BTUB - ECOLI - GREMLIN Contacts

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BTUB - Vitamin B12 transporter BtuB

UniProt:	P06129	Sequences: MIKKASLLTACSVTAFSAWAQDTSPDTLVVTANRFEQPRSTVLAPTTVVTRQDIDRWQSTSVNDVLRRLPGVDITQNGGSGQLSSIFIRGTNASHVLVLIDGVRLNLAGVSGSADLSQFPIALVQRVEYIRGPRSAVYGSDAIGGVVNIITTRDEPGTEISAGWGSNSYQNYDVSTQQQLGDKTRVTLLGDYAHTHGYDVVAYGNTGTQAQTDNDGFLSKTLYGALEHNFTDAWSGFVRGYGYDNRTNYDAYYSPGSPLLDTRKLYSQSWDAGLRYNGELIKSQLITSYSHSKDYNYDPHYGRYDSSATLDEMKQYTVQWANNVIVGHGSIGAGVDWQKQTTTPGTGYVEDGYDQRNTGIYLTGLQQVGDFTFEGAARSDDNSQFGRHGTWQTSAGWEFIEGYRFIASYGTSYKAPNLGQLYGFYGNPNLDPEKSKQWEGAFEGLTAGVNWRISGYRNDVSDLIDYDDHTLKYYNEGKARIKGVEATANFDTGPLTHTVSYDYVDARNAITDTPLLRRAKQQVKYQLDWQLYDFDWGITYQYLGTRYDKDYSSYPYQTVKMGGVSLWDLAVAYPVTSHLTVRGKIANLFDKDYETVYGYQTAGREYTLSGSYTF	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10126
Length:	614 (554)
Sequences:	52351 (42898)
Seq/√Len:	1822.5

ECOLI - BTUB CIRA YNCD FECA FHUE YDDB FHUA FEPA FIU

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
501_Y	521_Q	3.912	1.00
540_Y	565_S	3.816	1.00
184_T	228_H	3.725	1.00
457_R	482_K	3.419	1.00
377_A	389_G	3.413	1.00
403_Y	442_F	3.389	1.00
409_Y	436_K	3.336	1.00
582_R	609_S	3.311	1.00
411_T	436_K	3.189	1.00
535_D	572_A	3.162	1.00
234_W	278_G	3.159	1.00
192_Y	220_K	3.064	1.00
379_S	389_G	3.062	1.00
329_G	364_G	2.968	1.00
162_A	172_Y	2.771	1.00
498_T	526_Q	2.700	1.00
190_G	220_K	2.644	1.00
403_Y	444_G	2.637	1.00
237_F	275_R	2.583	1.00
457_R	480_R	2.471	1.00
371_F	397_W	2.425	1.00
51_R	55_D	2.381	1.00
449_V	490_F	2.365	1.00
126_R	150_I	2.344	1.00
567_W	589_F	2.333	1.00
444_G	451_W	2.289	1.00
334_G	361_Y	2.280	1.00
184_T	226_L	2.267	1.00
503_Y	521_Q	2.258	1.00
178_Q	186_V	2.256	1.00
585_I	588_L	2.250	1.00
235_S	277_N	2.233	1.00
584_K	607_T	2.219	1.00
234_W	276_Y	2.215	1.00
540_Y	567_W	2.175	1.00
124_V	149_I	2.173	1.00
542_Y	565_S	2.165	1.00
233_A	278_G	2.156	1.00
495_L	527_L	2.086	1.00
185_R	227_E	2.079	1.00
379_S	387_R	2.072	1.00
450_N	489_N	2.065	1.00
231_T	234_W	2.061	1.00
50_T	53_D	2.050	1.00
242_G	270_W	2.027	1.00
194_H	218_L	2.017	1.00
537_G	570_A	2.013	1.00
538_I	567_W	2.007	1.00
572_A	580_T	2.003	1.00
399_F	405_F	1.994	1.00
452_R	487_T	1.971	1.00
580_T	611_S	1.961	1.00
396_G	404_R	1.931	1.00
240_G	270_W	1.926	1.00
411_T	434_K	1.918	1.00
339_K	356_R	1.893	1.00
545_T	560_K	1.881	1.00
335_V	358_T	1.845	1.00
409_Y	438_W	1.831	1.00
579_L	612_Y	1.831	1.00
158_T	176_T	1.802	1.00
574_P	580_T	1.797	1.00
371_F	395_A	1.785	1.00
399_F	403_Y	1.784	1.00
244_D	268_Q	1.776	1.00
188_L	224_G	1.773	1.00
372_T	398_E	1.771	1.00
61_S	64_D	1.761	1.00
329_G	366_Q	1.732	1.00
227_E	235_S	1.721	1.00
100_I	105_L	1.719	1.00
463_L	479_A	1.718	1.00
496_T	528_D	1.715	1.00
534_F	573_Y	1.708	1.00
523_V	542_Y	1.701	1.00
455_G	482_K	1.685	1.00
466_Y	473_Y	1.683	1.00
191_D	221_T	1.673	1.00
539_T	568_D	1.661	1.00
495_L	529_W	1.644	1.00
437_Q	458_N	1.643	1.00
451_W	488_A	1.643	1.00
391_W	411_T	1.631	1.00
579_L	610_G	1.623	1.00
337_W	358_T	1.621	1.00
436_K	461_S	1.606	1.00
328_H	369_G	1.605	1.00
459_D	478_K	1.604	1.00
69_L	129_Y	1.594	1.00
48_V	128_E	1.594	1.00
459_D	480_R	1.589	1.00
101_D	225_A	1.583	1.00
227_E	237_F	1.583	1.00
406_I	441_A	1.582	1.00
236_G	276_Y	1.573	1.00
494_P	529_W	1.568	1.00
186_V	226_L	1.567	1.00
583_G	606_Y	1.562	1.00
125_Q	152_T	1.560	1.00
186_V	190_G	1.558	1.00
161_S	611_S	1.552	1.00
281_I	291_H	1.546	1.00
159_E	613_T	1.544	1.00
456_Y	504_V	1.543	1.00
497_H	527_L	1.542	1.00
593_Y	601_T	1.540	1.00
443_E	452_R	1.527	1.00
240_G	272_A	1.527	1.00
400_I	403_Y	1.526	1.00
183_K	228_H	1.525	1.00
330_S	367_Q	1.520	1.00
453_I	486_A	1.515	1.00
367_Q	372_T	1.513	1.00
448_G	490_F	1.512	1.00
575_V	581_V	1.508	1.00
229_N	235_S	1.504	1.00
339_K	354_D	1.500	1.00
542_Y	563_G	1.499	1.00
585_I	606_Y	1.486	1.00
406_I	443_E	1.479	1.00
52_Q	56_R	1.471	1.00
431_D	462_D	1.468	1.00
128_E	148_N	1.457	1.00
100_I	151_T	1.452	1.00
89_R	485_E	1.443	1.00
281_I	285_L	1.436	1.00
569_L	588_L	1.429	1.00
359_G	378_R	1.427	1.00
489_N	498_T	1.424	1.00
405_F	442_F	1.420	1.00
482_K	505_D	1.419	1.00
526_Q	539_T	1.417	1.00
391_W	395_A	1.409	1.00
51_R	152_T	1.409	1.00
497_H	525_Y	1.397	1.00
456_Y	483_G	1.392	1.00
281_I	289_Y	1.392	1.00
372_T	396_G	1.392	1.00
125_Q	153_R	1.391	1.00
465_D	476_E	1.387	1.00
88_I	145_G	1.386	1.00
281_I	288_S	1.383	1.00
449_V	488_A	1.382	1.00
585_I	604_R	1.374	1.00
394_S	408_S	1.370	1.00
535_D	574_P	1.370	1.00
185_R	229_N	1.370	1.00
528_D	537_G	1.368	1.00
434_K	462_D	1.365	1.00
579_L	583_G	1.356	1.00
439_E	454_S	1.345	1.00
407_A	438_W	1.339	1.00
192_Y	218_L	1.337	1.00
53_D	56_R	1.336	1.00
277_N	284_Q	1.333	1.00
414_K	433_E	1.330	1.00
71_G	502_D	1.330	1.00
359_G	380_D	1.329	1.00
57_W	68_R	1.325	1.00
453_I	484_V	1.324	1.00
188_L	222_L	1.322	1.00
101_D	151_T	1.321	1.00
330_S	365_L	1.311	1.00
285_L	318_V	1.306	1.00
363_T	374_E	1.301	1.00
581_V	610_G	1.298	1.00
541_Q	568_D	1.288	1.00
120_P	123_L	1.285	1.00
156_P	185_R	1.282	1.00
570_A	582_R	1.281	1.00
161_S	173_D	1.281	1.00
52_Q	55_D	1.280	1.00
534_F	571_V	1.278	1.00
323_N	330_S	1.276	1.00
375_G	393_T	1.275	1.00
238_V	272_A	1.265	1.00
536_W	571_V	1.263	1.00
153_R	227_E	1.261	1.00
336_D	359_G	1.258	1.00
287_T	318_V	1.255	1.00
586_A	605_E	1.251	1.00
175_S	187_T	1.251	1.00
496_T	530_Q	1.250	1.00
190_G	222_L	1.249	1.00
373_F	395_A	1.248	1.00
153_R	225_A	1.246	1.00
500_S	524_K	1.242	1.00
491_D	496_T	1.242	1.00
406_I	454_S	1.240	1.00
186_V	224_G	1.236	1.00
535_D	580_T	1.232	1.00
101_D	239_R	1.231	1.00
380_D	390_T	1.222	1.00
499_V	525_Y	1.220	1.00
568_D	586_A	1.215	1.00
329_G	334_G	1.213	1.00
608_L	612_Y	1.212	1.00
403_Y	407_A	1.208	1.00
242_G	268_Q	1.204	1.00
521_Q	544_G	1.200	1.00
230_F	236_G	1.196	1.00
455_G	484_V	1.194	1.00
163_G	609_S	1.193	1.00
235_S	279_E	1.188	1.00
64_D	67_R	1.187	1.00
236_G	274_L	1.186	1.00
89_R	439_E	1.186	1.00
440_G	455_G	1.186	1.00
580_T	613_T	1.185	1.00
38_P	41_T	1.184	1.00
365_L	374_E	1.183	1.00
158_T	162_A	1.182	1.00
281_I	290_S	1.177	1.00
317_T	336_D	1.174	1.00
187_T	225_A	1.171	1.00
572_A	582_R	1.171	1.00
575_V	579_L	1.168	1.00
438_W	459_D	1.165	1.00
291_H	314_K	1.156	1.00
47_T	131_R	1.154	1.00
163_G	171_N	1.154	1.00
222_L	242_G	1.149	1.00
502_D	522_Q	1.138	1.00
164_W	172_Y	1.135	1.00
270_W	274_L	1.134	1.00
451_W	486_A	1.131	1.00
15_A	18_A	1.130	1.00
233_A	279_E	1.130	1.00
543_L	546_R	1.126	1.00
189_L	223_Y	1.123	1.00
239_R	273_G	1.122	1.00
438_W	457_R	1.121	1.00
288_S	317_T	1.120	1.00
337_W	356_R	1.118	1.00
70_P	487_T	1.116	1.00
367_Q	370_D	1.105	1.00
567_W	591_K	1.103	1.00
131_R	485_E	1.101	1.00
72_V	88_I	1.098	1.00
285_L	289_Y	1.095	1.00
412_S	435_S	1.091	1.00
538_I	569_L	1.090	1.00
583_G	608_L	1.080	1.00
395_A	399_F	1.074	1.00
484_V	503_Y	1.070	1.00
358_T	381_D	1.067	1.00
489_N	496_T	1.067	1.00
407_A	440_G	1.065	1.00
164_W	170_Q	1.064	1.00
73_D	522_Q	1.063	1.00
461_S	478_K	1.063	1.00
237_F	277_N	1.061	1.00
143_I	435_S	1.059	1.00
289_Y	314_K	1.056	1.00
41_T	398_E	1.055	1.00
284_Q	321_A	1.053	1.00
24_S	27_T	1.051	1.00
335_V	360_I	1.051	1.00
481_I	506_A	1.050	1.00
497_H	504_V	1.049	1.00
567_W	588_L	1.048	1.00
365_L	372_T	1.042	1.00
435_S	458_N	1.037	1.00
374_E	394_S	1.037	1.00
99_L	104_R	1.036	1.00
360_I	379_S	1.036	1.00
125_Q	150_I	1.036	1.00
51_R	125_Q	1.027	1.00
528_D	535_D	1.025	1.00
97_L	104_R	1.023	1.00
281_I	286_I	1.021	1.00
530_Q	535_D	1.016	1.00
331_I	364_G	1.015	1.00
398_E	401_E	1.015	1.00
414_K	420_Q	1.014	1.00
508_N	511_T	1.012	1.00
128_E	150_I	1.008	1.00
441_A	454_S	1.007	1.00
570_A	584_K	1.006	1.00
541_Q	566_L	1.005	1.00
405_F	440_G	1.004	1.00
566_L	593_Y	1.003	1.00
523_V	544_G	1.003	1.00
514_P	520_K	1.001	1.00
373_F	393_T	0.998	1.00
398_E	404_R	0.997	1.00
168_S	196_H	0.996	1.00
236_G	240_G	0.993	1.00
582_R	611_S	0.993	1.00
25_P	28_L	0.990	1.00
69_L	72_V	0.990	1.00
490_F	497_H	0.989	1.00
527_L	538_I	0.988	1.00
285_L	320_W	0.987	1.00
281_I	287_T	0.985	1.00
285_L	288_S	0.985	1.00
328_H	366_Q	0.981	1.00
165_G	169_Y	0.981	1.00
451_W	455_G	0.976	1.00
317_T	338_Q	0.976	1.00
287_T	291_H	0.976	1.00
402_G	444_G	0.974	1.00
503_Y	520_K	0.974	1.00
170_Q	194_H	0.973	1.00
531_L	536_W	0.973	1.00
48_V	126_R	0.970	1.00
399_F	442_F	0.970	1.00
129_Y	147_V	0.968	1.00
282_K	285_L	0.968	1.00
543_L	564_V	0.966	1.00
43_L	394_S	0.960	1.00
216_G	248_N	0.958	1.00
275_R	286_I	0.957	1.00
494_P	530_Q	0.957	1.00
238_V	274_L	0.957	1.00
325_I	330_S	0.956	1.00
99_L	148_N	0.955	1.00
238_V	242_G	0.952	1.00
229_N	232_D	0.949	1.00
172_Y	192_Y	0.946	1.00
442_F	453_I	0.942	1.00
576_T	579_L	0.942	1.00
120_P	191_D	0.942	1.00
581_V	608_L	0.942	1.00
162_A	170_Q	0.942	1.00
123_L	189_L	0.942	1.00
287_T	316_Y	0.937	1.00
547_Y	560_K	0.935	1.00
574_P	613_T	0.935	1.00
230_F	234_W	0.932	1.00
438_W	442_F	0.930	1.00
571_V	585_I	0.929	1.00
435_S	460_V	0.928	1.00
276_Y	280_L	0.928	1.00
453_I	457_R	0.928	1.00
533_D	573_Y	0.926	1.00
390_T	413_Y	0.926	1.00
160_I	164_W	0.926	1.00
366_Q	375_G	0.925	1.00
578_H	612_Y	0.924	1.00
376_A	392_Q	0.924	1.00
225_A	237_F	0.920	1.00
420_Q	473_Y	0.919	1.00
448_G	491_D	0.916	1.00
17_S	20_A	0.915	1.00
404_R	443_E	0.915	1.00
155_E	185_R	0.912	1.00
456_Y	485_E	0.912	1.00
244_D	266_Y	0.911	1.00
123_L	223_Y	0.909	1.00
123_L	187_T	0.908	1.00
283_S	322_N	0.903	1.00
581_V	585_I	0.902	1.00
324_V	331_I	0.902	1.00
183_K	230_F	0.899	1.00
391_W	409_Y	0.898	1.00
159_E	611_S	0.898	1.00
25_P	29_V	0.898	1.00
336_D	361_Y	0.897	1.00
368_V	373_F	0.896	1.00
56_R	528_D	0.896	1.00
171_N	191_D	0.894	1.00
588_L	604_R	0.893	1.00
53_D	68_R	0.892	1.00
333_A	337_W	0.891	1.00
377_A	391_W	0.890	1.00
560_K	595_T	0.887	1.00
241_Y	271_D	0.885	1.00
586_A	607_T	0.885	1.00
479_A	515_L	0.883	1.00
181_G	184_T	0.883	1.00
86_I	147_V	0.882	1.00
136_A	376_A	0.881	1.00
164_W	168_S	0.880	1.00
169_Y	195_T	0.879	1.00
183_K	229_N	0.877	1.00
122_A	173_D	0.877	1.00
43_L	396_G	0.876	1.00
171_N	193_A	0.875	1.00
14_T	18_A	0.874	1.00
153_R	237_F	0.873	1.00
328_H	367_Q	0.873	1.00
433_E	460_V	0.872	1.00
98_V	147_V	0.871	1.00
138_Y	146_V	0.869	1.00
514_P	547_Y	0.865	1.00
590_D	603_G	0.865	1.00
159_E	175_S	0.865	1.00
360_I	364_G	0.863	1.00
417_N	420_Q	0.862	1.00
333_A	362_L	0.860	1.00
360_I	381_D	0.860	1.00
47_T	487_T	0.858	1.00
546_R	561_M	0.857	1.00
566_L	601_T	0.853	1.00
325_I	328_H	0.852	1.00
501_Y	523_V	0.851	1.00
14_T	17_S	0.850	1.00
173_D	191_D	0.850	1.00
70_P	500_S	0.849	1.00
466_Y	471_L	0.849	1.00
544_G	563_G	0.847	1.00
18_A	21_Q	0.847	1.00
104_R	141_D	0.847	1.00
326_V	331_I	0.846	1.00
62_V	149_I	0.845	1.00
231_T	278_G	0.844	1.00
33_N	37_Q	0.843	1.00
288_S	292_S	0.843	1.00
499_V	523_V	0.842	1.00
277_N	286_I	0.841	1.00
158_T	164_W	0.839	1.00
318_V	322_N	0.837	1.00
99_L	146_V	0.833	1.00
322_N	325_I	0.832	1.00
179_Q	185_R	0.832	1.00
174_V	178_Q	0.832	1.00
545_T	563_G	0.831	1.00
486_A	490_F	0.830	1.00
54_I	65_V	0.828	1.00
157_G	177_Q	0.825	1.00
222_L	226_L	0.824	1.00
86_I	98_V	0.823	1.00
395_A	407_A	0.823	1.00
59_S	65_V	0.821	1.00
68_R	539_T	0.820	1.00
282_K	322_N	0.820	1.00
71_G	131_R	0.816	1.00
250_D	261_D	0.814	1.00
287_T	290_S	0.813	1.00
220_K	224_G	0.811	1.00
332_G	336_D	0.810	1.00
530_Q	574_P	0.809	1.00
42_V	46_T	0.809	1.00
224_G	228_H	0.808	1.00
51_R	54_I	0.808	1.00
49_V	69_L	0.807	1.00
494_P	497_H	0.806	1.00
332_G	365_L	0.803	1.00
436_K	459_D	0.802	1.00
523_V	565_S	0.801	1.00
355_Q	384_Q	0.801	1.00
194_H	216_G	0.801	1.00
223_Y	241_Y	0.801	1.00
74_I	86_I	0.799	1.00
434_K	461_S	0.798	1.00
504_V	518_R	0.798	1.00
357_N	415_A	0.797	1.00
445_L	449_V	0.796	1.00
47_T	69_L	0.794	1.00
374_E	396_G	0.794	1.00
16_F	19_W	0.793	1.00
484_V	488_A	0.793	1.00
382_N	386_G	0.791	1.00
193_A	219_S	0.790	1.00
127_V	149_I	0.790	1.00
433_E	463_L	0.789	1.00
456_Y	502_D	0.788	1.00
23_T	26_D	0.786	1.00
45_P	439_E	0.784	1.00
319_Q	336_D	0.783	1.00
343_T	352_G	0.783	1.00
188_L	192_Y	0.783	1.00
89_R	483_G	0.782	1.00
521_Q	542_Y	0.781	1.00
286_I	290_S	0.779	1.00
393_T	409_Y	0.779	1.00
523_V	527_L	0.778	1.00
565_S	591_K	0.777	1.00
460_V	463_L	0.776	1.00
445_L	448_G	0.775	1.00
102_G	148_N	0.773	1.00
46_T	128_E	0.772	1.00
158_T	186_V	0.771	1.00
526_Q	537_G	0.770	1.00
172_Y	176_T	0.767	1.00
88_I	129_Y	0.767	1.00
21_Q	24_S	0.767	1.00
449_V	453_I	0.765	1.00
332_G	363_T	0.764	1.00
281_I	324_V	0.764	1.00
60_T	64_D	0.763	1.00
536_W	569_L	0.762	1.00
569_L	585_I	0.761	1.00
154_D	227_E	0.761	1.00
562_G	591_K	0.760	1.00
184_T	188_L	0.760	1.00
546_R	562_G	0.759	1.00
363_T	392_Q	0.759	1.00
175_S	189_L	0.758	1.00
498_T	528_D	0.757	1.00
319_Q	361_Y	0.757	1.00
220_K	244_D	0.754	1.00
282_K	286_I	0.754	1.00
578_H	613_T	0.753	1.00
282_K	288_S	0.753	1.00
89_R	456_Y	0.752	1.00
450_N	491_D	0.751	1.00
334_G	338_Q	0.751	1.00
324_V	333_A	0.750	1.00
97_L	146_V	0.747	1.00
121_I	124_V	0.745	1.00
283_S	320_W	0.744	1.00
497_H	502_D	0.743	1.00
274_L	278_G	0.743	1.00
56_R	535_D	0.743	1.00
23_T	28_L	0.742	1.00
246_R	266_Y	0.740	1.00
529_W	536_W	0.740	1.00
505_D	520_K	0.740	1.00
590_D	604_R	0.740	1.00
329_G	333_A	0.740	1.00
388_H	434_K	0.739	1.00
381_D	385_F	0.738	1.00
323_N	332_G	0.737	1.00
281_I	322_N	0.736	1.00
362_L	377_A	0.735	1.00
286_I	321_A	0.734	1.00
291_H	312_E	0.734	1.00
390_T	411_T	0.732	1.00
286_I	319_Q	0.731	1.00
187_T	223_Y	0.730	1.00
161_S	609_S	0.730	1.00
62_V	65_V	0.729	1.00
480_R	507_R	0.727	1.00
177_Q	187_T	0.726	1.00
154_D	185_R	0.726	1.00
577_S	612_Y	0.726	1.00
141_D	357_N	0.725	1.00
418_L	421_L	0.725	1.00
488_A	499_V	0.724	1.00
103_V	288_S	0.723	1.00
284_Q	287_T	0.723	1.00
31_T	34_R	0.722	1.00
547_Y	561_M	0.722	1.00
39_R	48_V	0.722	1.00
497_H	500_S	0.721	1.00
283_S	287_T	0.719	1.00
97_L	142_A	0.718	1.00
47_T	70_P	0.718	1.00
341_T	352_G	0.717	1.00
198_Y	603_G	0.715	1.00
277_N	282_K	0.715	1.00
67_R	541_Q	0.714	1.00
341_T	354_D	0.712	1.00
156_P	182_D	0.711	1.00
179_Q	182_D	0.710	1.00
458_N	481_I	0.708	1.00
160_I	174_V	0.705	1.00
155_E	177_Q	0.704	1.00
331_I	362_L	0.703	1.00
161_S	164_W	0.703	1.00
574_P	578_H	0.702	1.00
284_Q	323_N	0.700	1.00
589_F	592_D	0.700	1.00
95_H	433_E	0.700	1.00
73_D	519_A	0.699	1.00
584_K	609_S	0.699	1.00
513_T	547_Y	0.699	1.00
382_N	385_F	0.698	1.00
447_A	451_W	0.698	1.00
122_A	161_S	0.698	1.00
316_Y	320_W	0.697	1.00
520_K	544_G	0.697	1.00
230_F	276_Y	0.696	1.00
45_P	454_S	0.694	1.00
392_Q	408_S	0.694	1.00
446_T	449_V	0.694	1.00
279_E	284_Q	0.692	1.00
130_I	146_V	0.692	1.00
281_I	292_S	0.689	1.00
228_H	231_T	0.688	1.00
417_N	430_L	0.688	1.00
324_V	327_G	0.686	1.00
87_F	92_N	0.686	1.00
185_R	235_S	0.684	1.00
285_L	290_S	0.684	1.00
91_T	144_G	0.683	1.00
292_S	296_N	0.682	1.00
282_K	324_V	0.682	1.00
487_T	498_T	0.681	1.00
494_P	531_L	0.681	1.00
55_D	611_S	0.679	1.00
492_T	495_L	0.676	1.00
391_W	394_S	0.676	1.00
326_V	329_G	0.673	1.00
440_G	444_G	0.670	1.00
580_T	583_G	0.670	1.00
535_D	538_I	0.669	1.00
246_R	264_K	0.667	1.00
602_A	605_E	0.667	1.00
156_P	229_N	0.666	1.00
283_S	288_S	0.665	1.00
430_L	464_I	0.664	1.00
329_G	336_D	0.662	1.00
496_T	499_V	0.659	1.00
219_S	245_N	0.658	1.00
567_W	585_I	0.658	1.00
381_D	387_R	0.658	1.00
225_A	239_R	0.657	1.00
98_V	149_I	0.656	1.00
152_T	175_S	0.655	1.00
23_T	27_T	0.655	1.00
130_I	138_Y	0.655	1.00
373_F	377_A	0.654	1.00
184_T	230_F	0.654	1.00
364_G	375_G	0.653	1.00
355_Q	415_A	0.652	1.00
368_V	395_A	0.649	1.00
400_I	444_G	0.646	1.00
525_Y	565_S	0.645	1.00
280_L	320_W	0.644	1.00
527_L	531_L	0.643	1.00
282_K	290_S	0.643	1.00
91_T	460_V	0.643	1.00
417_N	421_L	0.642	1.00
464_I	473_Y	0.642	1.00
153_R	239_R	0.639	1.00
372_T	375_G	0.638	1.00
218_L	246_R	0.638	1.00
318_V	337_W	0.637	1.00
361_Y	378_R	0.637	1.00
72_V	86_I	0.636	1.00
132_G	439_E	0.636	1.00
158_T	174_V	0.634	1.00
133_P	410_G	0.633	1.00
131_R	487_T	0.633	1.00
313_M	340_Q	0.633	1.00
174_V	190_G	0.629	1.00
520_K	545_T	0.629	1.00
217_F	245_N	0.629	1.00
160_I	176_T	0.627	1.00
169_Y	193_A	0.627	1.00
363_T	376_A	0.627	1.00
504_V	522_Q	0.627	1.00
375_G	379_S	0.627	1.00
398_E	402_G	0.626	1.00
176_T	179_Q	0.626	1.00
281_I	284_Q	0.624	1.00
285_L	292_S	0.624	1.00
272_A	276_Y	0.623	1.00
245_N	267_S	0.620	1.00
573_Y	576_T	0.620	1.00
497_H	501_Y	0.618	1.00
408_S	439_E	0.618	1.00
533_D	574_P	0.616	1.00
64_D	586_A	0.615	1.00
464_I	475_N	0.615	1.00
166_S	606_Y	0.615	1.00
184_T	224_G	0.614	1.00
317_T	322_N	0.614	1.00
233_A	280_L	0.614	1.00
450_N	453_I	0.614	1.00
485_E	502_D	0.613	1.00
37_Q	41_T	0.613	1.00
289_Y	316_Y	0.611	1.00
152_T	159_E	0.610	1.00
279_E	282_K	0.610	1.00
98_V	116_L	0.609	1.00
491_D	494_P	0.607	1.00
497_H	503_Y	0.607	1.00
154_D	187_T	0.606	1.00
282_K	323_N	0.606	1.00
130_I	134_R	0.605	1.00
163_G	173_D	0.605	1.00
156_P	179_Q	0.605	1.00
26_D	29_V	0.603	1.00
322_N	333_A	0.602	1.00
65_V	121_I	0.602	1.00
330_S	333_A	0.602	1.00
481_I	504_V	0.601	1.00
317_T	321_A	0.599	1.00
413_Y	432_P	0.598	1.00
506_A	518_R	0.598	1.00
406_I	452_R	0.598	1.00
234_W	238_V	0.598	1.00
194_H	220_K	0.598	1.00
544_G	565_S	0.597	1.00
338_Q	357_N	0.597	1.00
87_F	95_H	0.597	1.00
153_R	235_S	0.596	1.00
393_T	397_W	0.596	1.00
522_Q	543_L	0.595	1.00
183_K	231_T	0.594	1.00
495_L	503_Y	0.594	1.00
332_G	335_V	0.594	1.00
540_Y	589_F	0.593	1.00
53_D	57_W	0.593	1.00
133_P	412_S	0.591	1.00
40_S	398_E	0.591	1.00
227_E	230_F	0.590	1.00
137_V	332_G	0.590	1.00
322_N	326_V	0.590	1.00
154_D	186_V	0.588	1.00
460_V	479_A	0.588	1.00
538_I	588_L	0.588	1.00
367_Q	398_E	0.587	1.00
339_K	358_T	0.587	1.00
125_Q	155_E	0.586	1.00
536_W	540_Y	0.586	1.00
70_P	131_R	0.586	1.00
288_S	291_H	0.585	1.00
506_A	515_L	0.585	1.00
275_R	288_S	0.584	1.00
565_S	589_F	0.584	1.00
486_A	501_Y	0.584	1.00
290_S	294_D	0.583	1.00
91_T	95_H	0.582	1.00
331_I	334_G	0.581	1.00
419_G	422_Y	0.581	1.00
331_I	335_V	0.581	1.00
269_S	292_S	0.581	1.00
176_T	186_V	0.579	1.00
88_I	96_V	0.576	1.00
370_D	401_E	0.575	1.00
608_L	611_S	0.575	1.00
281_I	293_K	0.574	1.00
319_Q	334_G	0.574	1.00
442_F	451_W	0.573	1.00
531_L	534_F	0.573	1.00
509_A	512_D	0.572	1.00
315_Q	338_Q	0.571	1.00
75_T	85_S	0.571	1.00
62_V	124_V	0.570	1.00
91_T	481_I	0.570	1.00
397_W	400_I	0.569	1.00
575_V	578_H	0.569	1.00
158_T	161_S	0.568	1.00
508_N	512_D	0.567	1.00
59_S	64_D	0.567	1.00
495_L	499_V	0.567	1.00
123_L	221_T	0.567	1.00
122_A	189_L	0.566	1.00
399_F	402_G	0.565	1.00
463_L	481_I	0.561	1.00
45_P	131_R	0.561	1.00
534_F	538_I	0.560	1.00
160_I	163_G	0.560	1.00
282_K	291_H	0.560	1.00
150_I	153_R	0.560	1.00
571_V	575_V	0.560	1.00
525_Y	540_Y	0.559	1.00
340_Q	355_Q	0.558	1.00
103_V	273_G	0.557	1.00
56_R	530_Q	0.557	1.00
293_K	310_L	0.556	1.00
566_L	590_D	0.556	1.00
43_L	374_E	0.555	1.00
397_W	402_G	0.555	1.00
480_R	505_D	0.555	1.00
366_Q	373_F	0.553	1.00
158_T	178_Q	0.552	1.00
530_Q	533_D	0.552	1.00
368_V	371_F	0.551	1.00
290_S	317_T	0.550	1.00
96_V	144_G	0.549	1.00
606_Y	610_G	0.548	1.00
165_G	168_S	0.547	1.00
431_D	434_K	0.547	1.00
490_F	527_L	0.547	1.00
283_S	286_I	0.546	1.00
366_Q	369_G	0.544	1.00
438_W	455_G	0.541	1.00
314_K	317_T	0.539	1.00
487_T	500_S	0.539	1.00
430_L	475_N	0.539	1.00
336_D	339_K	0.538	1.00
53_D	498_T	0.537	1.00
413_Y	434_K	0.537	1.00
183_K	232_D	0.537	1.00
195_T	217_F	0.535	1.00
40_S	404_R	0.535	1.00
439_E	485_E	0.535	1.00
436_K	457_R	0.533	1.00
321_A	332_G	0.532	1.00
425_Y	472_K	0.532	1.00
569_L	583_G	0.531	1.00
433_E	462_D	0.530	1.00
136_A	392_Q	0.530	1.00
516_L	547_Y	0.530	1.00
196_H	216_G	0.529	1.00
570_A	607_T	0.528	1.00
272_A	275_R	0.528	1.00
224_G	240_G	0.527	1.00
167_N	605_E	0.527	1.00
120_P	171_N	0.527	1.00
412_S	437_Q	0.526	1.00
282_K	292_S	0.526	1.00
20_A	23_T	0.526	1.00
43_L	46_T	0.525	1.00
314_K	318_V	0.525	1.00
283_S	290_S	0.524	1.00
519_A	543_L	0.524	1.00
224_G	227_E	0.523	1.00
382_N	415_A	0.523	1.00
115_D	118_Q	0.523	1.00
462_D	475_N	0.521	1.00
275_R	278_G	0.520	1.00
371_F	399_F	0.518	1.00
160_I	612_Y	0.517	1.00
16_F	20_A	0.517	1.00
392_Q	410_G	0.517	1.00
91_T	458_N	0.517	1.00
524_K	539_T	0.516	1.00
293_K	312_E	0.516	1.00
39_R	46_T	0.514	1.00
151_T	225_A	0.514	1.00
41_T	367_Q	0.514	1.00
159_E	162_A	0.514	1.00
393_T	396_G	0.513	1.00
37_Q	42_V	0.513	1.00
248_N	264_K	0.511	1.00
24_S	28_L	0.511	1.00
579_L	608_L	0.510	1.00
41_T	372_T	0.509	1.00
527_L	536_W	0.508	1.00
223_Y	239_R	0.508	1.00
234_W	280_L	0.508	1.00
527_L	540_Y	0.506	1.00
370_D	397_W	0.505	1.00
329_G	367_Q	0.505	1.00
513_T	557_Q	0.505	1.00
130_I	135_S	0.504	1.00
575_V	610_G	0.503	1.00
490_F	499_V	0.503	1.00
226_L	238_V	0.503	1.00
44_A	392_Q	0.502	1.00
463_L	477_G	0.502	1.00
288_S	296_N	0.502	1.00
67_R	568_D	0.501	1.00
286_I	289_Y	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2gufA	1	0.8974	100	0.155	Contact Map
2hdiA	1	0.8664	100	0.217	Contact Map
1kmoA	1	0.9365	100	0.226	Contact Map
1xkwA	1	0.9088	100	0.232	Contact Map
3v8xA	1	0.9251	100	0.233	Contact Map
3qlbA	1	0.8941	100	0.234	Contact Map
3efmA	1	0.8534	100	0.237	Contact Map
3fhhA	1	0.9104	100	0.238	Contact Map
4b7oA	1	0.9169	100	0.252	Contact Map
4cu4A	1	0.9316	100	0.252	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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