GREMLIN Database
ILVD - Dihydroxy-acid dehydratase
UniProt: P05791 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG10496
Length: 616 (540)
Sequences: 1810 (708)
Seq/√Len: 30.5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
449_T548_A5.6591.00
41_N73_E4.4821.00
40_V107_M4.1431.00
130_L288_A4.0421.00
115_A239_I3.8791.00
220_S323_M3.6891.00
53_L121_N3.6771.00
263_A346_N3.4421.00
273_I304_L3.4371.00
548_A559_Q3.4351.00
40_V116_M3.3401.00
141_I352_V3.2331.00
177_S180_Q3.1781.00
455_Y464_A3.1691.00
208_T214_S3.0201.00
141_I239_I2.9981.00
104_V132_A2.9601.00
260_A265_F2.9531.00
452_A541_I2.8781.00
234_N237_K2.8541.00
64_I69_G2.7981.00
550_D553_N2.7971.00
436_V549_I2.7781.00
170_Q175_K2.7221.00
302_D306_R2.6971.00
457_S460_D2.6531.00
149_E191_T2.6521.00
449_T559_Q2.6341.00
87_H111_H2.6251.00
347_R358_P2.6201.00
54_R58_K2.5981.00
141_I238_R2.5911.00
210_A271_L2.5861.00
454_V541_I2.5140.99
54_R61_A2.4880.99
269_M296_F2.4610.99
453_K474_D2.4230.99
266_E346_N2.4140.99
118_C140_V2.3910.99
496_T516_F2.3370.99
271_L332_V2.3260.99
64_I236_G2.3160.99
238_R241_E2.3140.99
270_T308_V2.3130.99
152_K184_V2.3050.99
349_V357_L2.2980.99
561_S564_E2.2900.99
446_L552_P2.2850.99
452_A547_I2.2740.99
484_K534_S2.2640.99
453_K543_D2.2570.99
548_A557_Q2.2170.99
69_G240_V2.2080.99
542_E571_A2.1210.98
454_V543_D2.1160.98
63_Q66_A2.0930.98
37_I64_I2.0860.98
117_V143_V2.0820.98
340_D347_R2.0780.98
472_A506_K2.0740.98
262_K294_I2.0520.98
558_L565_L2.0400.98
263_A348_D2.0380.98
445_I448_F2.0350.97
37_I239_I2.0340.97
541_I547_I2.0330.97
176_V180_Q2.0290.97
283_L286_L2.0290.97
468_G502_M2.0160.97
37_I115_A2.0120.97
461_A476_V2.0100.97
259_I264_A2.0050.97
475_V547_I1.9810.97
341_R358_P1.9790.97
143_V235_A1.9720.97
436_V551_I1.9720.97
321_Y408_C1.9680.97
349_V356_T1.9450.97
511_I528_V1.9320.97
471_V506_K1.9280.96
434_C556_I1.9250.96
170_Q173_D1.8670.96
356_T359_Q1.8540.96
560_V564_E1.8460.95
475_V549_I1.8260.95
429_F541_I1.8250.95
210_A332_V1.8120.95
449_T546_L1.8090.95
214_S218_N1.8040.95
59_L233_L1.7990.95
282_V435_I1.7870.95
229_K233_L1.7750.94
538_I541_I1.7670.94
365_D379_R1.7420.94
453_K464_A1.7390.94
447_K550_D1.7130.93
51_V192_C1.7100.93
587_R591_F1.7080.93
342_A412_L1.7040.93
210_A345_L1.7020.93
266_E303_K1.7010.93
564_E567_A1.6850.93
456_E460_D1.6820.93
453_K472_A1.6730.92
537_S558_L1.6690.92
39_V64_I1.6640.92
355_L359_Q1.6540.92
546_L559_Q1.6400.92
66_A237_K1.6180.91
541_I558_L1.6150.91
447_K548_A1.6120.91
121_N145_G1.6040.91
442_D445_I1.5940.90
88_G588_Q1.5910.90
460_D463_E1.5720.90
562_D565_L1.5620.89
131_M291_E1.5600.89
290_Q605_K1.5500.89
166_D170_Q1.5370.89
602_S605_K1.5320.89
480_Y571_A1.5210.88
565_L568_R1.5210.88
429_F537_S1.5100.88
39_V61_A1.5060.88
149_E222_L1.5000.87
38_A41_N1.4960.87
59_L229_K1.4920.87
63_Q67_A1.4920.87
117_V239_I1.4800.87
595_A599_L1.4740.87
417_S446_L1.4730.86
471_V504_L1.4700.86
463_E467_G1.4670.86
465_I501_S1.4630.86
69_G236_G1.4610.86
431_E604_D1.4550.86
464_A470_V1.4540.86
539_G570_E1.4530.86
453_K469_K1.4480.86
523_L604_D1.4450.85
406_N414_H1.4280.85
35_P69_G1.4230.85
580_W583_K1.4080.84
265_F288_A1.4020.84
64_I71_A1.3820.83
173_D504_L1.3820.83
410_R414_H1.3780.83
208_T288_A1.3740.82
338_E341_R1.3740.82
243_T249_Q1.3590.82
39_V116_M1.3580.82
183_Q187_S1.3570.82
170_Q180_Q1.3510.81
60_V117_V1.3420.81
244_K249_Q1.3400.81
572_Q579_A1.3390.81
453_K471_V1.3380.81
540_L569_R1.3340.80
528_V538_I1.3330.80
478_I520_T1.3300.80
333_I381_G1.3250.80
541_I560_V1.3210.80
134_L292_A1.3100.79
532_A538_I1.3040.79
269_M301_I1.3020.79
408_C416_Y1.2930.78
87_H188_A1.2870.78
310_Q317_S1.2870.78
95_P600_A1.2870.78
359_Q362_E1.2840.78
542_E564_E1.2790.77
564_E568_R1.2690.77
511_I556_I1.2670.77
537_S541_I1.2670.77
411_S414_H1.2660.77
321_Y416_Y1.2570.76
56_L224_T1.2560.76
529_S602_S1.2550.76
242_L252_E1.2520.76
178_D363_Q1.2510.76
356_T360_T1.2410.75
56_L59_L1.2310.75
474_D543_D1.2240.74
306_R423_A1.2230.74
456_E479_R1.2170.74
367_M379_R1.2160.74
579_A582_P1.2130.74
63_Q237_K1.2060.73
452_A475_V1.1950.72
334_G409_I1.1900.72
365_D377_M1.1870.72
431_E537_S1.1800.71
55_D229_K1.1800.71
61_A236_G1.1760.71
350_K355_L1.1760.71
53_L73_E1.1720.71
263_A266_E1.1680.71
432_N604_D1.1670.71
271_L336_L1.1620.70
41_N53_L1.1590.70
290_Q295_D1.1570.70
230_Q233_L1.1540.70
560_V565_L1.1490.69
511_I547_I1.1460.69
242_L259_I1.1350.68
282_V298_M1.1310.68
258_N350_K1.1290.68
299_S431_E1.1280.68
210_A336_L1.1260.68
259_I350_K1.1100.67
560_V568_R1.1040.66
579_A583_K1.0950.66
150_A153_T1.0930.65
347_R356_T1.0920.65
268_A335_I1.0900.65
325_D408_C1.0900.65
118_C142_F1.0890.65
498_F501_S1.0880.65
562_D566_A1.0880.65
444_S507_A1.0870.65
238_R242_L1.0830.65
273_I308_V1.0730.64
134_L260_A1.0710.64
38_A73_E1.0690.64
443_D446_L1.0680.64
453_K470_V1.0680.64
353_L356_T1.0650.63
337_G361_L1.0620.63
462_V498_F1.0590.63
111_H588_Q1.0580.63
341_R413_E1.0570.63
215_Q219_G1.0560.63
299_S303_K1.0560.63
265_F268_A1.0520.62
563_A567_A1.0520.62
539_G580_W1.0500.62
456_E538_I1.0500.62
318_T408_C1.0490.62
268_A349_V1.0450.62
358_P361_L1.0440.62
238_R252_E1.0400.62
302_D423_A1.0380.61
474_D506_K1.0360.61
116_M140_V1.0360.61
261_S294_I1.0360.61
242_L254_A1.0360.61
62_E66_A1.0340.61
149_E225_H1.0320.61
132_A256_P1.0310.61
64_I240_V1.0230.60
299_S426_Y1.0200.60
130_L265_F1.0180.60
594_R598_S1.0060.59
75_N107_M1.0040.59
254_A350_K1.0040.59
442_D506_K1.0030.59
328_R363_Q1.0030.59
353_L360_T1.0030.59
465_I504_L1.0010.59
99_L106_Y0.9980.58
58_K62_E0.9970.58
174_P502_M0.9950.58
88_G586_E0.9930.58
207_L268_A0.9900.58
349_V359_Q0.9880.58
406_N411_S0.9880.58
345_L357_L0.9860.57
207_L422_L0.9840.57
318_T321_Y0.9830.57
550_D555_G0.9810.57
565_L569_R0.9790.57
457_S463_E0.9790.57
31_D69_G0.9740.56
448_F507_A0.9730.56
130_L256_P0.9730.56
59_L62_E0.9720.56
108_V113_A0.9720.56
461_A474_D0.9710.56
537_S540_L0.9700.56
207_L323_M0.9690.56
265_F296_F0.9690.56
471_V474_D0.9670.56
62_E65_E0.9650.56
452_A546_L0.9630.56
455_Y478_I0.9620.55
463_E469_K0.9620.55
98_E239_I0.9570.55
311_L335_I0.9570.55
453_K468_G0.9570.55
88_G111_H0.9530.55
55_D224_T0.9520.55
353_L359_Q0.9520.55
285_L296_F0.9480.54
188_A282_V0.9410.54
206_C275_M0.9410.54
130_L208_T0.9390.54
63_Q233_L0.9360.53
263_A349_V0.9360.53
429_F558_L0.9350.53
436_V441_V0.9310.53
36_I70_V0.9310.53
561_S565_L0.9300.53
98_E600_A0.9250.53
156_S166_D0.9240.52
462_V494_Y0.9210.52
62_E233_L0.9200.52
337_G341_R0.9170.52
472_A507_A0.9160.52
354_G357_L0.9080.51
243_T255_L0.9080.51
298_M604_D0.9060.51
537_S565_L0.9060.51
338_E412_L0.9040.51
338_E413_E0.8990.50
432_N538_I0.8990.50
302_D419_D0.8990.50
451_P546_L0.8990.50
453_K467_G0.8970.50
150_A325_D0.8940.50
53_L236_G0.8900.50
242_L251_D0.8890.50
153_T156_S0.8880.50
87_H132_A0.8870.50
112_C188_A0.8870.50
358_P362_E0.8840.49
459_D463_E0.8800.49
563_A566_A0.8750.49
169_I503_G0.8660.48
104_V118_C0.8640.48
464_A543_D0.8630.48
297_T604_D0.8620.48
117_V236_G0.8610.47
460_D464_A0.8600.47
367_M370_Q0.8600.47
153_T184_V0.8600.47
540_L565_L0.8590.47
557_Q562_D0.8560.47
351_N356_T0.8540.47
234_N241_E0.8480.46
254_A349_V0.8460.46
219_G222_L0.8460.46
65_E71_A0.8450.46
314_V326_V0.8440.46
460_D469_K0.8440.46
356_T361_L0.8390.46
99_L153_T0.8360.45
600_A604_D0.8320.45
53_L332_V0.8310.45
501_S504_L0.8300.45
243_T253_S0.8300.45
460_D543_D0.8290.45
301_I604_D0.8270.45
351_N360_T0.8250.45
180_Q496_T0.8220.44
64_I239_I0.8200.44
423_A552_P0.8200.44
150_A326_V0.8150.44
282_V442_D0.8150.44
169_I500_K0.8140.44
149_E224_T0.8120.44
601_T604_D0.8080.43
449_T557_Q0.8060.43
176_V332_V0.8040.43
88_G584_N0.8040.43
262_K266_E0.8040.43
214_S219_G0.8040.43
263_A347_R0.8030.43
314_V436_V0.8020.43
332_V461_A0.8000.43
270_T304_L0.7990.43
429_F479_R0.7960.42
91_L487_P0.7960.42
88_G595_A0.7960.42
419_D423_A0.7940.42
442_D446_L0.7940.42
103_S107_M0.7930.42
31_D34_K0.7910.42
297_T431_E0.7900.42
480_Y539_G0.7890.42
334_G411_S0.7880.42
429_F538_I0.7820.41
454_V558_L0.7780.41
153_T166_D0.7780.41
333_I361_L0.7750.41
441_V446_L0.7670.40
239_I242_L0.7670.40
152_K167_A0.7670.40
349_V358_P0.7660.40
529_S604_D0.7650.40
535_G539_G0.7640.40
61_A71_A0.7620.40
290_Q604_D0.7620.40
69_G208_T0.7610.40
362_E537_S0.7590.39
572_Q580_W0.7560.39
34_K70_V0.7550.39
260_A296_F0.7500.39
170_Q176_V0.7490.39
132_A138_I0.7490.39
443_D552_P0.7490.39
441_V551_I0.7480.39
111_H236_G0.7470.39
600_A607_A0.7440.38
167_A184_V0.7440.38
261_S484_K0.7430.38
411_S567_A0.7410.38
494_Y498_F0.7400.38
207_L210_A0.7400.38
211_L268_A0.7390.38
424_V435_I0.7340.38
455_Y460_D0.7340.38
460_D538_I0.7330.37
166_D188_A0.7330.37
581_T584_N0.7320.37
38_A107_M0.7310.37
297_T300_D0.7280.37
564_E569_R0.7270.37
264_A285_L0.7250.37
104_V107_M0.7250.37
528_V556_I0.7230.37
455_Y470_V0.7230.37
283_L297_T0.7220.37
560_V566_A0.7210.37
250_N255_L0.7200.36
134_L256_P0.7200.36
429_F511_I0.7190.36
219_G335_I0.7180.36
306_R419_D0.7170.36
191_T218_N0.7170.36
62_E237_K0.7140.36
173_D494_Y0.7130.36
37_I141_I0.7110.36
532_A539_G0.7090.36
429_F451_P0.7090.36
301_I419_D0.7080.36
140_V256_P0.7080.36
203_S260_A0.7080.36
425_L436_V0.7060.35
561_S567_A0.7040.35
542_E569_R0.7020.35
357_L360_T0.7020.35
178_D328_R0.7020.35
155_L180_Q0.7010.35
230_Q237_K0.6990.35
176_V596_Y0.6980.35
249_Q253_S0.6980.35
299_S320_K0.6960.35
179_S241_E0.6960.35
222_L596_Y0.6950.35
268_A356_T0.6930.35
111_H263_A0.6920.34
236_G308_V0.6910.34
66_A233_L0.6900.34
145_G187_S0.6890.34
141_I203_S0.6860.34
268_A359_Q0.6860.34
135_R268_A0.6850.34
337_G380_A0.6850.34
59_L63_Q0.6840.34
240_V243_T0.6820.34
342_A413_E0.6820.34
332_V335_I0.6820.34
251_D538_I0.6810.34
41_N56_L0.6800.34
222_L225_H0.6740.33
259_I268_A0.6740.33
41_N65_E0.6700.33
251_D283_L0.6670.33
35_P207_L0.6660.33
269_M297_T0.6650.33
87_H459_D0.6630.32
210_A218_N0.6620.32
244_K250_N0.6620.32
108_V138_I0.6600.32
580_W584_N0.6600.32
345_L529_S0.6600.32
56_L60_V0.6590.32
155_L166_D0.6580.32
449_T511_I0.6580.32
43_F58_K0.6570.32
103_S106_Y0.6570.32
357_L361_L0.6560.32
419_D446_L0.6530.32
461_A498_F0.6520.32
60_V236_G0.6510.32
282_V301_I0.6510.32
454_V477_V0.6500.31
477_V528_V0.6500.31
221_L335_I0.6490.31
423_A540_L0.6490.31
337_G365_D0.6490.31
528_V557_Q0.6480.31
381_G399_T0.6470.31
243_T250_N0.6460.31
41_N206_C0.6450.31
470_V506_K0.6440.31
314_V335_I0.6430.31
155_L320_K0.6420.31
186_R408_C0.6410.31
565_L572_Q0.6410.31
254_A356_T0.6400.31
540_L570_E0.6400.31
112_C186_R0.6400.31
176_V179_S0.6390.31
153_T188_A0.6380.31
102_D516_F0.6380.31
537_S542_E0.6370.31
155_L158_Q0.6370.31
271_L538_I0.6370.31
222_L332_V0.6360.31
362_E380_A0.6350.30
283_L302_D0.6340.30
37_I117_V0.6320.30
154_K157_D0.6320.30
459_D584_N0.6320.30
566_A570_E0.6310.30
135_R596_Y0.6300.30
54_R59_L0.6300.30
51_V224_T0.6290.30
534_S604_D0.6290.30
130_L260_A0.6260.30
354_G360_T0.6260.30
86_G316_P0.6250.30
47_V78_A0.6250.30
69_G351_N0.6250.30
66_A294_I0.6250.30
58_K61_A0.6240.30
451_P475_V0.6230.30
314_V327_H0.6230.30
210_A335_I0.6230.30
283_L299_S0.6230.30
470_V543_D0.6220.30
58_K467_G0.6220.30
38_A187_S0.6220.30
132_A135_R0.6220.30
496_T523_L0.6210.30
80_D85_M0.6190.29
310_Q417_S0.6180.29
170_Q184_V0.6170.29
596_Y609_R0.6160.29
219_G361_L0.6160.29
462_V478_I0.6160.29
250_N253_S0.6150.29
560_V563_A0.6130.29
130_L134_L0.6130.29
470_V474_D0.6120.29
92_Y136_L0.6120.29
352_V356_T0.6120.29
428_N558_L0.6110.29
53_L218_N0.6100.29
412_L582_P0.6100.29
255_L258_N0.6100.29
470_V476_V0.6090.29
34_K37_I0.6090.29
360_T364_Y0.6090.29
447_K549_I0.6080.29
436_V552_P0.6070.29
130_L294_I0.6070.29
99_L102_D0.6060.29
35_P500_K0.6060.29
325_D363_Q0.6060.29
81_D89_G0.6050.28
118_C207_L0.6050.28
191_T407_G0.6040.28
449_T555_G0.6040.28
173_D500_K0.6040.28
295_D424_V0.6020.28
320_K406_N0.6020.28
269_M285_L0.6020.28
341_R472_A0.6020.28
283_L586_E0.5960.28
341_R361_L0.5940.28
325_D328_R0.5940.28
361_L381_G0.5930.28
302_D554_R0.5930.28
340_D345_L0.5920.28
166_D169_I0.5910.28
542_E572_Q0.5900.27
67_A236_G0.5900.27
349_V353_L0.5900.27
179_S352_V0.5890.27
35_P534_S0.5880.27
262_K303_K0.5880.27
252_E255_L0.5880.27
532_A558_L0.5870.27
242_L594_R0.5870.27
520_T524_S0.5870.27
538_I547_I0.5860.27
562_D570_E0.5860.27
69_G117_V0.5860.27
318_T416_Y0.5860.27
569_R572_Q0.5860.27
273_I282_V0.5860.27
533_A600_A0.5850.27
304_L436_V0.5850.27
572_Q578_K0.5840.27
87_H424_V0.5830.27
114_D550_D0.5820.27
548_A555_G0.5820.27
447_K553_N0.5820.27
262_K346_N0.5800.27
143_V264_A0.5800.27
43_F168_M0.5800.27
547_I566_A0.5780.27
436_V475_V0.5780.27
426_Y431_E0.5780.27
177_S480_Y0.5780.27
461_A478_I0.5770.27
432_N605_K0.5770.27
341_R347_R0.5760.27
562_D571_A0.5750.27
283_L453_K0.5750.27
80_D205_N0.5750.27
61_A115_A0.5740.26
32_F240_V0.5740.26
406_N410_R0.5730.26
142_F208_T0.5690.26
334_G378_F0.5690.26
290_Q424_V0.5680.26
332_V345_L0.5680.26
572_Q581_T0.5680.26
525_I549_I0.5670.26
230_Q234_N0.5670.26
34_K141_I0.5660.26
179_S467_G0.5650.26
215_Q335_I0.5650.26
253_S258_N0.5650.26
61_A73_E0.5650.26
270_T342_A0.5650.26
155_L442_D0.5650.26
121_N236_G0.5650.26
557_Q560_V0.5650.26
455_Y543_D0.5630.26
266_E270_T0.5620.26
462_V466_L0.5620.26
135_R299_S0.5620.26
282_V503_G0.5620.26
341_R401_D0.5610.26
583_K586_E0.5600.26
465_I516_F0.5600.26
235_A260_A0.5590.26
221_L327_H0.5590.26
133_S140_V0.5570.25
103_S539_G0.5570.25
285_L538_I0.5570.25
350_K359_Q0.5570.25
153_T381_G0.5570.25
56_L73_E0.5560.25
582_P585_R0.5560.25
334_G337_G0.5550.25
182_D186_R0.5550.25
35_P240_V0.5550.25
233_L237_K0.5550.25
44_T107_M0.5540.25
333_I378_F0.5540.25
254_A359_Q0.5540.25
563_A568_R0.5540.25
459_D478_I0.5540.25
233_L542_E0.5540.25
259_I425_L0.5530.25
55_D59_L0.5520.25
303_K307_K0.5520.25
67_A70_V0.5510.25
442_D520_T0.5510.25
429_F548_A0.5510.25
552_P555_G0.5510.25
185_E421_G0.5500.25
553_N557_Q0.5500.25
114_D142_F0.5500.25
453_K460_D0.5500.25
273_I305_S0.5500.25
135_R283_L0.5500.25
539_G558_L0.5500.25
167_A187_S0.5490.25
88_G137_N0.5490.25
135_R595_A0.5490.25
347_R357_L0.5490.25
275_M335_I0.5480.25
116_M288_A0.5480.25
82_G89_G0.5480.25
500_K503_G0.5470.25
511_I541_I0.5460.25
93_S110_A0.5450.25
268_A361_L0.5450.25
168_M494_Y0.5450.25
134_L288_A0.5440.25
297_T422_L0.5440.25
58_K65_E0.5430.25
340_D368_L0.5430.25
333_I368_L0.5420.25
447_K552_P0.5420.25
33_G251_D0.5420.25
80_D197_G0.5420.25
451_P477_V0.5410.24
332_V336_L0.5410.24
134_L257_R0.5410.24
221_L378_F0.5410.24
175_K379_R0.5410.24
241_E252_E0.5400.24
368_L434_C0.5400.24
540_L581_T0.5400.24
595_A609_R0.5400.24
150_A184_V0.5390.24
566_A569_R0.5390.24
342_A417_S0.5380.24
443_D528_V0.5380.24
306_R409_I0.5380.24
368_L418_K0.5350.24
361_L368_L0.5350.24
118_C210_A0.5350.24
207_L600_A0.5340.24
149_E456_E0.5340.24
221_L332_V0.5340.24
179_S244_K0.5340.24
436_V525_I0.5340.24
203_S265_F0.5330.24
436_V524_S0.5330.24
242_L353_L0.5330.24
452_A474_D0.5330.24
54_R191_T0.5330.24
369_T608_V0.5330.24
477_V558_L0.5330.24
271_L285_L0.5320.24
250_N475_V0.5320.24
377_M380_A0.5320.24
270_T332_V0.5320.24
137_N257_R0.5310.24
445_I502_M0.5310.24
67_A550_D0.5310.24
307_K344_L0.5310.24
336_L596_Y0.5310.24
303_K562_D0.5310.24
170_Q501_S0.5310.24
417_S529_S0.5300.24
308_V409_I0.5300.24
307_K341_R0.5290.24
61_A72_K0.5280.24
70_V208_T0.5280.24
460_D584_N0.5270.24
143_V414_H0.5270.24
180_Q183_Q0.5270.24
363_Q379_R0.5260.24
469_K542_E0.5260.24
314_V332_V0.5260.24
485_G533_A0.5250.24
219_G565_L0.5240.23
144_S205_N0.5240.23
352_V375_K0.5230.23
337_G401_D0.5230.23
55_D58_K0.5230.23
507_A570_E0.5230.23
125_I202_N0.5220.23
340_D361_L0.5220.23
459_D466_L0.5220.23
282_V500_K0.5210.23
111_H474_D0.5210.23
34_K236_G0.5210.23
451_P607_A0.5210.23
258_N294_I0.5200.23
333_I404_R0.5200.23
301_I435_I0.5200.23
436_V556_I0.5200.23
140_V534_S0.5180.23
341_R412_L0.5170.23
61_A70_V0.5170.23
313_K327_H0.5160.23
279_T520_T0.5140.23
130_L210_A0.5140.23
452_A477_V0.5140.23
425_L432_N0.5140.23
135_R256_P0.5140.23
251_D484_K0.5130.23
259_I596_Y0.5130.23
281_T304_L0.5130.23
172_A317_S0.5120.23
180_Q402_D0.5120.23
86_G496_T0.5110.23
501_S538_I0.5110.23
219_G240_V0.5110.23
311_L457_S0.5110.23
317_S528_V0.5100.23
134_L298_M0.5100.23
141_I234_N0.5100.23
192_C224_T0.5090.23
80_D144_S0.5090.23
69_G241_E0.5090.23
69_G320_K0.5080.23
104_V134_L0.5080.23
350_K358_P0.5070.23
322_H520_T0.5070.23
112_C283_L0.5070.23
218_N231_L0.5070.23
72_K351_N0.5060.22
132_A298_M0.5060.22
224_T235_A0.5060.22
283_L487_P0.5050.22
90_M276_G0.5050.22
333_I380_A0.5050.22
264_A539_G0.5050.22
42_S203_S0.5040.22
381_G411_S0.5030.22
336_L361_L0.5030.22
79_V110_A0.5030.22
175_K188_A0.5030.22
81_D94_L0.5020.22
286_L299_S0.5020.22
311_L338_E0.5020.22
479_R539_G0.5010.22
81_D86_G0.5000.22
150_A322_H0.5000.22
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2gp4A 2 0.8084 100 0.166 Contact Map
2b99A 3 0.211 72.5 0.983 Contact Map
1c41A 6 0.2078 59 0.984 Contact Map
3rfqA 5 0.2127 56.8 0.985 Contact Map
1q5xA 3 0.224 51.9 0.985 Contact Map
4xcwA 3 0.25 48.4 0.985 Contact Map
4nwoA 3 0.2256 44.7 0.986 Contact Map
4wzzA 1 0.4627 41.6 0.986 Contact Map
2is8A 3 0.2159 39.8 0.986 Contact Map
4lhbA 4 0.2192 39.2 0.986 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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