PTRA - ECOLI - GREMLIN Contacts

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PTRA - Protease 3

UniProt:	P05458	Sequences: MPRSTWFKALLLLVALWAPLSQAETGWQPIQETIRKSDKDNRQYQAIRLDNGMVVLLVSDPQAVKSLSALVVPVGSLEDPEAYQGLAHYLEHMSLMGSKKYPQADSLAEYLKMHGGSHNASTAPYRTAFYLEVENDALPGAVDRLADAIAEPLLDKKYAERERNAVNAELTMARTRDGMRMAQVSAETINPAHPGSKFSGGNLETLSDKPGNPVQQALKDFHEKYYSANLMKAVIYSNKPLPELAKMAADTFGRVPNKESKKPEITVPVVTDAQKGIIIHYVPALPRKVLRVEFRIDNNSAKFRSKTDELITYLIGNRSPGTLSDWLQKQGLVEGISANSDPIVNGNSGVLAISASLTDKGLANRDQVVAAIFSYLNLLREKGIDKQYFDELANVLDIDFRYPSITRDMDYVEWLADTMIRVPVEHTLDAVNIADRYDAKAVKERLAMMTPQNARIWYISPKEPHNKTAYFVDAPYQVDKISAQTFADWQKKAADIALSLPELNPYIPDDFSLIKSEKKYDHPELIVDESNLRVVYAPSRYFASEPKADVSLILRNPKAMDSARNQVMFALNDYLAGLALDQLSNQASVGGISFSTNANNGLMVNANGYTQRLPQLFQALLEGYFSYTATEDQLEQAKSWYNQMMDSAEKGKAFEQAIMPAQMLSQVPYFSRDERRKILPSITLKEVLAYRDALKSGARPEFMVIGNMTEAQATTLARDVQKQLGADGSEWCRNKDVVVDKKQSVIFEKAGNSTDSALAAVFVPTGYDEYTSSAYSSLLGQIVQPWFYNQLRTEEQLGYAVFAFPMSVGRQWGMGFLLQSNDKQPSFLWERYKAFFPTAEAKLRAMKPDEFAQIQQAVITQMLQAPQTLGEEASKLSKDFDRGNMRFDSRDKIVAQIKLLTPQKLADFFHQAVVEPQGMAILSQISGSQNGKAEYVHPEGWKVWENVSALQQTMPLMSEKNE	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10786
Length:	962 (861)
Sequences:	3732 (3051)
Seq/√Len:	104.0

ECOLI - PTRA PQQL

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
386_K	390_D	5.777	1.00
364_N	367_Q	5.289	1.00
378_L	382_K	4.755	1.00
216_Q	220_D	4.573	1.00
82_A	217_A	4.283	1.00
848_P	852_A	4.248	1.00
580_L	585_N	4.104	1.00
580_L	583_L	4.066	1.00
45_Q	242_P	3.982	1.00
790_Q	794_E	3.981	1.00
375_Y	378_L	3.877	1.00
100_K	143_D	3.779	1.00
99_K	151_E	3.702	1.00
377_N	381_E	3.628	1.00
847_K	850_E	3.493	1.00
245_A	249_A	3.409	1.00
824_Q	827_F	3.305	1.00
90_L	154_L	3.271	1.00
240_P	243_E	3.246	1.00
504_N	508_P	3.234	1.00
494_A	498_L	3.171	1.00
631_E	635_E	3.086	1.00
589_V	592_I	3.044	1.00
904_K	907_D	3.039	1.00
217_A	220_D	2.990	1.00
562_S	565_N	2.971	1.00
579_A	582_Q	2.889	1.00
564_R	686_E	2.879	1.00
903_Q	907_D	2.840	1.00
235_I	248_A	2.838	1.00
370_A	374_S	2.832	1.00
215_Q	219_K	2.809	1.00
220_D	224_K	2.779	1.00
587_A	590_G	2.774	1.00
761_V	833_K	2.743	1.00
587_A	592_I	2.708	1.00
642_N	680_P	2.676	1.00
582_Q	585_N	2.632	1.00
423_P	426_H	2.600	1.00
87_A	221_F	2.557	1.00
355_A	372_I	2.528	1.00
606_A	616_L	2.496	1.00
397_D	401_R	2.491	1.00
447_A	451_P	2.488	1.00
440_K	444_E	2.487	1.00
333_V	336_I	2.481	1.00
840_E	910_H	2.456	1.00
565_N	693_A	2.431	1.00
848_P	902_P	2.417	1.00
76_S	199_S	2.392	1.00
901_T	904_K	2.379	1.00
468_T	472_V	2.375	1.00
472_V	476_Y	2.373	1.00
72_V	231_M	2.342	1.00
778_L	900_L	2.329	1.00
902_P	906_A	2.290	1.00
827_F	830_E	2.285	1.00
579_A	583_L	2.264	1.00
380_R	447_A	2.246	1.00
54_V	232_K	2.245	1.00
505_P	508_P	2.244	1.00
503_L	506_Y	2.209	1.00
101_Y	143_D	2.199	1.00
868_T	872_E	2.199	1.00
121_S	128_A	2.193	1.00
863_L	894_V	2.163	1.00
891_D	895_A	2.162	1.00
220_D	223_E	2.155	1.00
869_L	872_E	2.135	1.00
903_Q	906_A	2.106	1.00
100_K	147_D	2.104	1.00
424_V	427_T	2.091	1.00
495_D	508_P	2.075	1.00
747_F	750_A	2.066	1.00
830_E	834_A	2.061	1.00
139_P	247_M	2.040	1.00
88_H	91_E	2.026	1.00
57_L	241_L	2.024	1.00
892_K	895_A	2.008	1.00
495_D	499_S	2.005	1.00
424_V	428_L	2.003	1.00
533_R	701_E	2.002	1.00
482_S	485_T	1.999	1.00
859_I	898_K	1.998	1.00
837_P	841_A	1.985	1.00
229_N	257_N	1.984	1.00
48_R	54_V	1.975	1.00
907_D	911_Q	1.944	1.00
45_Q	241_L	1.919	1.00
622_E	626_S	1.909	1.00
475_P	479_D	1.905	1.00
834_A	837_P	1.895	1.00
88_H	92_H	1.876	1.00
498_L	504_N	1.873	1.00
89_Y	159_A	1.867	1.00
508_P	511_F	1.867	1.00
377_N	380_R	1.866	1.00
205_T	208_D	1.863	1.00
110_Y	140_G	1.858	1.00
550_V	704_V	1.856	1.00
498_L	507_I	1.851	1.00
583_L	586_Q	1.848	1.00
495_D	498_L	1.844	1.00
779_L	909_F	1.844	1.00
423_P	428_L	1.842	1.00
580_L	584_S	1.837	1.00
159_A	215_Q	1.831	1.00
675_R	678_I	1.821	1.00
174_R	198_F	1.820	1.00
246_K	249_A	1.797	1.00
775_Y	900_L	1.796	1.00
94_S	152_P	1.791	1.00
45_Q	245_A	1.784	1.00
276_G	280_H	1.776	1.00
426_H	429_D	1.745	1.00
565_N	686_E	1.742	1.00
750_A	753_S	1.740	1.00
71_V	128_A	1.736	1.00
868_T	871_E	1.730	1.00
851_F	902_P	1.724	1.00
286_P	359_D	1.718	1.00
921_I	924_Q	1.718	1.00
772_S	911_Q	1.714	1.00
81_E	197_K	1.707	1.00
303_F	436_R	1.695	1.00
70_L	233_A	1.681	1.00
581_D	585_N	1.672	1.00
834_A	838_T	1.663	1.00
786_W	850_E	1.652	1.00
746_I	749_K	1.648	1.00
511_F	515_K	1.646	1.00
381_E	447_A	1.639	1.00
170_L	200_G	1.633	1.00
455_R	461_P	1.632	1.00
672_R	678_I	1.625	1.00
470_Y	473_D	1.625	1.00
219_K	223_E	1.625	1.00
276_G	281_Y	1.620	1.00
332_L	336_I	1.615	1.00
587_A	591_G	1.613	1.00
775_Y	908_F	1.612	1.00
47_I	55_V	1.602	1.00
276_G	282_V	1.596	1.00
685_K	689_A	1.586	1.00
835_F	838_T	1.586	1.00
98_S	152_P	1.585	1.00
498_L	502_E	1.580	1.00
771_T	904_K	1.579	1.00
232_K	419_M	1.572	1.00
294_F	373_F	1.570	1.00
579_A	584_S	1.568	1.00
397_D	404_S	1.551	1.00
892_K	896_Q	1.545	1.00
494_A	497_A	1.545	1.00
68_S	73_P	1.538	1.00
57_L	239_K	1.535	1.00
779_L	905_L	1.533	1.00
711_A	714_T	1.529	1.00
233_A	252_F	1.526	1.00
608_G	616_L	1.521	1.00
243_E	246_K	1.520	1.00
590_G	598_A	1.505	1.00
487_A	490_Q	1.504	1.00
852_A	856_Q	1.502	1.00
483_A	487_A	1.492	1.00
121_S	126_R	1.490	1.00
322_T	326_W	1.476	1.00
503_L	508_P	1.474	1.00
487_A	491_K	1.473	1.00
614_P	618_Q	1.472	1.00
580_L	586_Q	1.471	1.00
192_A	267_V	1.468	1.00
895_A	899_L	1.464	1.00
535_V	701_E	1.463	1.00
94_S	98_S	1.461	1.00
568_M	686_E	1.458	1.00
634_L	684_L	1.458	1.00
301_A	304_R	1.457	1.00
499_S	508_P	1.447	1.00
125_Y	195_G	1.441	1.00
709_T	712_Q	1.440	1.00
683_T	686_E	1.437	1.00
424_V	429_D	1.436	1.00
511_F	514_I	1.436	1.00
271_T	274_Q	1.428	1.00
236_Y	412_V	1.424	1.00
139_P	251_T	1.414	1.00
579_A	585_N	1.411	1.00
314_L	384_I	1.411	1.00
572_N	576_A	1.407	1.00
612_R	615_Q	1.406	1.00
353_I	372_I	1.401	1.00
151_E	255_V	1.400	1.00
672_R	675_R	1.400	1.00
203_L	207_S	1.393	1.00
536_Y	708_M	1.393	1.00
684_L	688_L	1.390	1.00
827_F	831_R	1.388	1.00
426_H	431_V	1.383	1.00
138_L	244_L	1.380	1.00
615_Q	618_Q	1.378	1.00
183_Q	187_E	1.376	1.00
554_L	700_P	1.369	1.00
481_I	489_W	1.368	1.00
93_M	218_L	1.367	1.00
782_I	905_L	1.367	1.00
581_D	584_S	1.361	1.00
367_Q	370_A	1.359	0.99
239_K	244_L	1.359	0.99
293_E	352_A	1.358	0.99
888_D	892_K	1.357	0.99
762_F	813_G	1.357	0.99
749_K	752_N	1.357	0.99
705_I	873_A	1.352	0.99
91_E	169_E	1.351	0.99
119_N	122_T	1.348	0.99
745_V	748_E	1.347	0.99
504_N	507_I	1.345	0.99
69_A	416_A	1.343	0.99
188_T	456_I	1.343	0.99
771_T	896_Q	1.340	0.99
297_D	448_M	1.339	0.99
322_T	325_D	1.337	0.99
774_A	896_Q	1.332	0.99
379_L	384_I	1.332	0.99
532_L	721_Q	1.331	0.99
333_V	355_A	1.328	0.99
862_M	897_I	1.323	0.99
159_A	218_L	1.323	0.99
184_V	187_E	1.322	0.99
52_G	257_N	1.320	0.99
366_D	370_A	1.318	0.99
312_T	351_L	1.309	0.99
131_L	141_A	1.307	0.99
837_P	840_E	1.306	0.99
712_Q	715_T	1.305	0.99
92_H	122_T	1.304	0.99
374_S	378_L	1.304	0.99
332_L	364_N	1.297	0.99
88_H	122_T	1.297	0.99
494_A	508_P	1.296	0.99
274_Q	280_H	1.294	0.99
223_E	258_K	1.294	0.99
488_D	491_K	1.294	0.99
718_R	722_K	1.290	0.99
752_N	755_D	1.289	0.99
423_P	427_T	1.288	0.99
246_K	250_D	1.287	0.99
654_F	802_F	1.284	0.99
621_L	723_Q	1.284	0.99
441_A	444_E	1.278	0.99
154_L	215_Q	1.277	0.99
325_D	329_K	1.273	0.99
876_L	880_F	1.273	0.99
83_Y	205_T	1.269	0.99
85_G	201_G	1.267	0.99
390_D	393_A	1.266	0.99
852_A	855_Q	1.266	0.99
494_A	499_S	1.265	0.99
685_K	688_L	1.261	0.99
635_E	638_K	1.260	0.99
715_T	718_R	1.255	0.99
789_N	794_E	1.254	0.99
322_T	327_L	1.252	0.99
858_V	897_I	1.250	0.99
247_M	250_D	1.247	0.99
91_E	122_T	1.245	0.99
525_L	533_R	1.244	0.99
277_I	281_Y	1.243	0.99
288_K	359_D	1.233	0.99
68_S	75_G	1.232	0.99
561_D	565_N	1.232	0.99
869_L	873_A	1.226	0.99
745_V	749_K	1.223	0.99
147_D	151_E	1.220	0.99
439_A	443_K	1.219	0.99
494_A	507_I	1.219	0.99
91_E	119_N	1.209	0.99
528_D	533_R	1.209	0.99
202_N	205_T	1.206	0.99
173_A	200_G	1.205	0.99
484_Q	488_D	1.200	0.99
828_L	835_F	1.198	0.99
122_T	162_E	1.196	0.99
859_I	894_V	1.194	0.99
498_L	508_P	1.191	0.99
485_T	488_D	1.190	0.99
96_M	793_T	1.189	0.99
711_A	715_T	1.186	0.99
88_H	119_N	1.180	0.99
371_A	375_Y	1.180	0.99
500_L	503_L	1.178	0.99
67_L	412_V	1.176	0.99
769_E	772_S	1.175	0.99
552_L	702_F	1.173	0.98
119_N	792_R	1.172	0.98
582_Q	586_Q	1.170	0.98
745_V	750_A	1.170	0.98
243_E	247_M	1.169	0.98
746_I	750_A	1.169	0.98
634_L	638_K	1.168	0.98
688_L	692_D	1.167	0.98
829_W	833_K	1.167	0.98
276_G	279_I	1.165	0.98
831_R	834_A	1.164	0.98
277_I	282_V	1.163	0.98
686_E	689_A	1.161	0.98
590_G	594_F	1.159	0.98
277_I	280_H	1.158	0.98
507_I	510_D	1.155	0.98
142_V	247_M	1.152	0.98
73_P	76_S	1.146	0.98
778_L	905_L	1.143	0.98
98_S	154_L	1.141	0.98
327_L	333_V	1.140	0.98
53_M	233_A	1.140	0.98
468_T	475_P	1.137	0.98
369_V	456_I	1.135	0.98
92_H	119_N	1.132	0.98
438_D	441_A	1.132	0.98
88_H	169_E	1.131	0.98
432_N	435_D	1.128	0.98
422_V	426_H	1.126	0.98
642_N	646_D	1.123	0.98
120_A	169_E	1.122	0.98
319_S	322_T	1.120	0.98
652_K	655_E	1.119	0.98
122_T	792_R	1.119	0.98
156_K	160_E	1.119	0.98
92_H	120_A	1.119	0.98
182_A	186_A	1.118	0.98
91_E	120_A	1.117	0.98
748_E	752_N	1.115	0.98
744_S	747_F	1.111	0.98
70_L	231_M	1.110	0.98
154_L	219_K	1.107	0.98
428_L	431_V	1.105	0.98
597_N	603_M	1.105	0.98
119_N	201_G	1.105	0.98
311_I	442_V	1.104	0.98
493_A	497_A	1.103	0.98
590_G	593_S	1.103	0.98
156_K	215_Q	1.103	0.98
99_K	255_V	1.097	0.98
122_T	169_E	1.096	0.98
771_T	775_Y	1.094	0.98
325_D	582_Q	1.094	0.98
653_A	656_Q	1.094	0.98
108_A	118_H	1.092	0.98
292_V	369_V	1.092	0.98
502_E	505_P	1.090	0.98
88_H	120_A	1.090	0.98
89_Y	218_L	1.088	0.98
828_L	832_Y	1.087	0.98
562_S	693_A	1.086	0.98
631_E	684_L	1.084	0.97
455_R	462_K	1.083	0.97
484_Q	487_A	1.083	0.97
227_S	230_L	1.078	0.97
907_D	910_H	1.077	0.97
427_T	430_A	1.077	0.97
498_L	505_P	1.077	0.97
74_V	221_F	1.076	0.97
397_D	406_T	1.074	0.97
880_F	883_G	1.074	0.97
780_G	803_A	1.073	0.97
792_R	799_Y	1.071	0.97
373_F	377_N	1.071	0.97
119_N	799_Y	1.069	0.97
359_D	363_A	1.067	0.97
499_S	503_L	1.067	0.97
568_M	687_V	1.066	0.97
579_A	586_Q	1.064	0.97
528_D	531_N	1.063	0.97
91_E	799_Y	1.063	0.97
279_I	282_V	1.063	0.97
84_Q	202_N	1.063	0.97
146_A	150_A	1.062	0.97
838_T	844_R	1.061	0.97
88_H	799_Y	1.060	0.97
802_F	815_G	1.060	0.97
435_D	439_A	1.060	0.97
120_A	162_E	1.057	0.97
355_A	368_V	1.056	0.97
661_A	762_F	1.055	0.97
56_L	415_L	1.055	0.97
483_A	486_F	1.054	0.97
788_Y	793_T	1.054	0.97
920_A	924_Q	1.054	0.97
323_L	372_I	1.053	0.97
179_M	186_A	1.052	0.97
100_K	151_E	1.051	0.97
145_L	148_A	1.050	0.97
249_A	253_G	1.049	0.97
688_L	691_R	1.047	0.97
831_R	835_F	1.046	0.97
778_L	897_I	1.045	0.97
185_S	293_E	1.045	0.97
672_R	682_I	1.045	0.97
167_N	203_L	1.044	0.97
462_K	465_H	1.043	0.97
879_D	883_G	1.040	0.97
581_D	586_Q	1.040	0.97
689_A	693_A	1.039	0.97
748_E	751_G	1.039	0.97
747_F	751_G	1.039	0.97
397_D	403_P	1.038	0.97
70_L	73_P	1.038	0.97
841_A	845_A	1.036	0.97
756_S	759_A	1.033	0.97
791_L	798_G	1.032	0.97
94_S	222_H	1.027	0.97
90_L	218_L	1.026	0.96
92_H	799_Y	1.026	0.96
120_A	792_R	1.025	0.96
92_H	169_E	1.022	0.96
538_P	710_E	1.022	0.96
756_S	765_T	1.022	0.96
501_P	505_P	1.022	0.96
275_K	280_H	1.021	0.96
121_S	130_Y	1.020	0.96
497_A	507_I	1.019	0.96
493_A	496_I	1.019	0.96
84_Q	217_A	1.017	0.96
326_W	375_Y	1.017	0.96
139_P	250_D	1.016	0.96
167_N	207_S	1.015	0.96
588_S	612_R	1.015	0.96
614_P	719_D	1.014	0.96
235_I	239_K	1.013	0.96
444_E	447_A	1.009	0.96
851_F	905_L	1.008	0.96
191_P	196_S	1.007	0.96
156_K	216_Q	1.003	0.96
495_D	504_N	1.002	0.96
738_V	742_K	1.002	0.96
275_K	279_I	1.001	0.96
88_H	162_E	0.999	0.96
825_P	828_L	0.998	0.96
98_S	148_A	0.998	0.96
510_D	513_L	0.997	0.96
422_V	428_L	0.996	0.96
139_P	244_L	0.996	0.96
825_P	835_F	0.996	0.96
119_N	162_E	0.996	0.96
514_I	712_Q	0.996	0.96
368_V	372_I	0.995	0.96
360_K	363_A	0.995	0.96
565_N	568_M	0.994	0.96
124_P	199_S	0.992	0.96
247_M	251_T	0.991	0.96
158_Y	161_R	0.991	0.96
896_Q	899_L	0.990	0.96
64_V	867_Q	0.990	0.96
638_K	679_L	0.990	0.96
588_S	591_G	0.987	0.96
173_A	179_M	0.986	0.96
868_T	873_A	0.986	0.96
468_T	471_F	0.984	0.96
176_R	179_M	0.983	0.96
461_P	464_P	0.980	0.95
826_S	830_E	0.979	0.95
162_E	169_E	0.979	0.95
423_P	431_V	0.979	0.95
855_Q	897_I	0.977	0.95
83_Y	197_K	0.974	0.95
503_L	507_I	0.971	0.95
96_M	158_Y	0.971	0.95
303_F	440_K	0.971	0.95
840_E	913_V	0.970	0.95
495_D	506_Y	0.970	0.95
170_L	173_A	0.967	0.95
318_R	322_T	0.967	0.95
140_G	144_R	0.967	0.95
333_V	340_S	0.962	0.95
638_K	642_N	0.962	0.95
824_Q	840_E	0.961	0.95
312_T	338_A	0.961	0.95
275_K	281_Y	0.961	0.95
499_S	504_N	0.957	0.95
836_F	840_E	0.957	0.95
677_K	681_S	0.956	0.95
893_I	897_I	0.956	0.95
895_A	898_K	0.955	0.95
307_T	441_A	0.955	0.95
749_K	753_S	0.954	0.95
708_M	713_A	0.950	0.95
398_I	402_Y	0.949	0.95
617_F	716_L	0.945	0.94
91_E	792_R	0.944	0.94
274_Q	277_I	0.938	0.94
422_V	425_E	0.938	0.94
146_A	251_T	0.937	0.94
508_P	514_I	0.936	0.94
167_N	171_T	0.934	0.94
818_L	828_L	0.934	0.94
653_A	665_S	0.934	0.94
568_M	572_N	0.933	0.94
673_D	676_R	0.933	0.94
72_V	149_I	0.932	0.94
424_V	431_V	0.930	0.94
190_N	350_V	0.929	0.94
66_S	135_N	0.926	0.94
463_E	466_N	0.926	0.94
99_K	254_R	0.926	0.94
820_S	828_L	0.926	0.94
625_F	725_G	0.925	0.94
169_E	792_R	0.925	0.94
501_P	507_I	0.925	0.94
152_P	222_H	0.923	0.94
425_E	431_V	0.923	0.94
59_S	241_L	0.922	0.94
714_T	718_R	0.921	0.94
92_H	162_E	0.918	0.94
104_A	161_R	0.917	0.94
494_A	504_N	0.917	0.94
830_E	833_K	0.917	0.94
591_G	594_F	0.916	0.93
590_G	596_T	0.916	0.93
426_H	430_A	0.914	0.93
498_L	503_L	0.913	0.93
73_P	232_K	0.913	0.93
143_D	147_D	0.913	0.93
592_I	598_A	0.913	0.93
652_K	656_Q	0.913	0.93
172_M	200_G	0.912	0.93
101_Y	147_D	0.912	0.93
385_D	388_Y	0.912	0.93
462_K	466_N	0.912	0.93
614_P	716_L	0.907	0.93
68_S	141_A	0.907	0.93
682_I	686_E	0.906	0.93
216_Q	223_E	0.905	0.93
180_R	183_Q	0.904	0.93
57_L	244_L	0.903	0.93
94_S	148_A	0.903	0.93
93_M	115_G	0.903	0.93
88_H	792_R	0.900	0.93
704_V	713_A	0.900	0.93
848_P	903_Q	0.898	0.93
775_Y	905_L	0.897	0.93
673_D	678_I	0.895	0.93
92_H	792_R	0.894	0.93
326_W	330_Q	0.893	0.93
757_A	825_P	0.893	0.93
322_T	388_Y	0.892	0.93
336_I	340_S	0.891	0.93
93_M	96_M	0.890	0.92
568_M	690_Y	0.890	0.92
133_V	141_A	0.889	0.92
471_F	475_P	0.889	0.92
629_A	688_L	0.888	0.92
502_E	507_I	0.888	0.92
738_V	744_S	0.887	0.92
455_R	459_I	0.886	0.92
744_S	748_E	0.886	0.92
150_A	255_V	0.884	0.92
290_L	355_A	0.883	0.92
501_P	508_P	0.882	0.92
401_R	404_S	0.881	0.92
113_M	116_G	0.879	0.92
782_I	854_I	0.879	0.92
816_F	832_Y	0.878	0.92
151_E	254_R	0.878	0.92
83_Y	217_A	0.877	0.92
511_F	516_S	0.877	0.92
592_I	596_T	0.875	0.92
477_Q	481_I	0.874	0.92
502_E	508_P	0.869	0.92
150_A	254_R	0.869	0.92
57_L	245_A	0.868	0.92
377_N	447_A	0.866	0.91
423_P	429_D	0.866	0.91
572_N	691_R	0.866	0.91
502_E	506_Y	0.865	0.91
748_E	753_S	0.865	0.91
659_M	662_Q	0.864	0.91
539_S	542_F	0.863	0.91
70_L	74_V	0.862	0.91
909_F	913_V	0.862	0.91
68_S	235_I	0.861	0.91
782_I	846_M	0.861	0.91
338_A	351_L	0.859	0.91
910_H	914_V	0.859	0.91
94_S	149_I	0.858	0.91
69_A	128_A	0.856	0.91
587_A	598_A	0.855	0.91
571_L	637_A	0.855	0.91
109_E	112_K	0.854	0.91
673_D	677_K	0.854	0.91
566_Q	569_F	0.853	0.91
453_N	461_P	0.852	0.91
663_M	666_Q	0.851	0.91
101_Y	144_R	0.851	0.91
689_A	692_D	0.851	0.91
89_Y	166_V	0.850	0.91
841_A	844_R	0.849	0.91
83_Y	224_K	0.849	0.91
233_A	248_A	0.849	0.91
497_A	508_P	0.848	0.91
783_V	839_A	0.848	0.91
203_L	206_L	0.847	0.90
146_A	248_A	0.844	0.90
851_F	855_Q	0.844	0.90
486_F	490_Q	0.844	0.90
292_V	372_I	0.843	0.90
832_Y	835_F	0.841	0.90
119_N	166_V	0.840	0.90
379_L	446_L	0.840	0.90
179_M	183_Q	0.840	0.90
776_S	908_F	0.837	0.90
119_N	169_E	0.837	0.90
497_A	504_N	0.836	0.90
143_D	251_T	0.835	0.90
155_D	158_Y	0.835	0.90
71_V	416_A	0.834	0.90
571_L	682_I	0.833	0.90
453_N	463_E	0.831	0.90
376_L	380_R	0.831	0.90
775_Y	904_K	0.829	0.90
326_W	371_A	0.829	0.90
501_P	506_Y	0.829	0.90
71_V	126_R	0.829	0.90
729_S	732_C	0.829	0.90
643_Q	647_S	0.828	0.89
96_M	788_Y	0.828	0.89
746_I	751_G	0.828	0.89
872_E	876_L	0.828	0.89
416_A	419_M	0.827	0.89
180_R	184_V	0.826	0.89
84_Q	205_T	0.824	0.89
538_P	708_M	0.823	0.89
165_A	796_Q	0.823	0.89
797_L	818_L	0.822	0.89
497_A	503_L	0.822	0.89
478_V	481_I	0.821	0.89
849_D	853_Q	0.821	0.89
128_A	413_E	0.820	0.89
129_F	226_Y	0.820	0.89
580_L	587_A	0.818	0.89
492_K	496_I	0.817	0.89
422_V	427_T	0.817	0.89
675_R	679_L	0.816	0.89
120_A	799_Y	0.816	0.89
137_A	140_G	0.814	0.89
65_K	132_E	0.813	0.89
575_L	634_L	0.812	0.89
497_A	502_E	0.812	0.89
229_N	260_S	0.812	0.89
568_M	678_I	0.810	0.88
244_L	248_A	0.809	0.88
180_R	187_E	0.809	0.88
548_A	708_M	0.809	0.88
508_P	515_K	0.809	0.88
122_T	799_Y	0.808	0.88
275_K	278_I	0.806	0.88
335_G	356_S	0.806	0.88
180_R	186_A	0.805	0.88
578_L	633_Q	0.804	0.88
95_L	148_A	0.803	0.88
169_E	799_Y	0.803	0.88
234_V	412_V	0.803	0.88
86_L	90_L	0.803	0.88
563_A	670_F	0.802	0.88
588_S	615_Q	0.801	0.88
105_D	108_A	0.801	0.88
76_S	124_P	0.801	0.88
668_P	672_R	0.798	0.88
241_L	245_A	0.795	0.88
120_A	201_G	0.795	0.88
446_L	450_T	0.795	0.88
147_D	150_A	0.795	0.88
678_I	682_I	0.795	0.88
554_L	602_L	0.794	0.87
787_F	801_V	0.794	0.87
507_I	511_F	0.793	0.87
270_V	275_K	0.791	0.87
653_A	661_A	0.791	0.87
454_A	462_K	0.790	0.87
423_P	430_A	0.789	0.87
397_D	400_F	0.788	0.87
494_A	502_E	0.788	0.87
499_S	502_E	0.786	0.87
633_Q	636_Q	0.785	0.87
270_V	273_A	0.785	0.87
76_S	200_G	0.784	0.87
476_Y	480_K	0.784	0.87
135_N	243_E	0.784	0.87
905_L	908_F	0.783	0.87
166_V	206_L	0.782	0.87
788_Y	797_L	0.782	0.87
501_P	504_N	0.781	0.87
771_T	899_L	0.781	0.87
404_S	407_R	0.780	0.87
876_L	879_D	0.780	0.87
108_A	788_Y	0.779	0.86
585_N	590_G	0.779	0.86
104_A	158_Y	0.778	0.86
75_G	128_A	0.778	0.86
498_L	501_P	0.778	0.86
498_L	506_Y	0.778	0.86
656_Q	661_A	0.772	0.86
455_R	463_E	0.770	0.86
585_N	591_G	0.770	0.86
91_E	162_E	0.769	0.86
722_K	725_G	0.769	0.86
127_T	226_Y	0.768	0.86
471_F	474_A	0.768	0.86
114_H	117_S	0.766	0.86
791_L	801_V	0.765	0.85
493_A	498_L	0.765	0.85
67_L	132_E	0.764	0.85
269_V	273_A	0.763	0.85
824_Q	828_L	0.763	0.85
653_A	660_P	0.763	0.85
829_W	920_A	0.762	0.85
114_H	137_A	0.761	0.85
521_D	891_D	0.761	0.85
614_P	712_Q	0.761	0.85
397_D	402_Y	0.761	0.85
863_L	898_K	0.761	0.85
478_V	486_F	0.760	0.85
535_V	703_M	0.760	0.85
469_A	473_D	0.757	0.85
920_A	923_S	0.757	0.85
441_A	445_R	0.755	0.85
610_T	706_G	0.754	0.85
814_M	832_Y	0.752	0.84
635_E	639_S	0.751	0.84
602_L	694_L	0.751	0.84
744_S	749_K	0.750	0.84
787_F	816_F	0.749	0.84
139_P	243_E	0.749	0.84
77_L	98_S	0.749	0.84
657_A	760_A	0.748	0.84
156_K	219_K	0.745	0.84
873_A	876_L	0.744	0.84
877_S	880_F	0.744	0.84
80_P	220_D	0.743	0.84
646_D	680_P	0.742	0.84
779_L	908_F	0.741	0.84
282_V	286_P	0.741	0.84
111_L	118_H	0.741	0.84
427_T	431_V	0.740	0.83
200_G	472_V	0.740	0.83
477_Q	480_K	0.740	0.83
461_P	465_H	0.740	0.83
476_Y	479_D	0.740	0.83
495_D	505_P	0.739	0.83
550_V	613_L	0.737	0.83
706_G	710_E	0.736	0.83
894_V	898_K	0.736	0.83
676_R	680_P	0.736	0.83
58_V	236_Y	0.736	0.83
470_Y	474_A	0.736	0.83
642_N	676_R	0.735	0.83
872_E	875_K	0.733	0.83
68_S	76_S	0.733	0.83
878_K	882_R	0.732	0.83
526_I	717_A	0.729	0.83
504_N	511_F	0.729	0.83
332_L	340_S	0.728	0.82
790_Q	834_A	0.728	0.82
457_W	462_K	0.727	0.82
759_A	829_W	0.726	0.82
374_S	377_N	0.726	0.82
524_E	710_E	0.725	0.82
779_L	913_V	0.724	0.82
170_L	203_L	0.724	0.82
142_V	235_I	0.723	0.82
46_A	54_V	0.723	0.82
828_L	836_F	0.723	0.82
69_A	231_M	0.721	0.82
98_S	147_D	0.720	0.82
438_D	611_Q	0.719	0.82
110_Y	114_H	0.718	0.82
775_Y	779_L	0.718	0.82
425_E	429_D	0.718	0.82
162_E	792_R	0.718	0.82
401_R	406_T	0.717	0.82
187_E	190_N	0.715	0.81
638_K	683_T	0.715	0.81
877_S	881_D	0.714	0.81
802_F	817_L	0.714	0.81
237_S	244_L	0.713	0.81
125_Y	346_G	0.713	0.81
583_L	587_A	0.712	0.81
737_V	741_K	0.712	0.81
416_A	420_I	0.712	0.81
589_V	594_F	0.712	0.81
358_T	364_N	0.712	0.81
434_A	437_Y	0.711	0.81
422_V	431_V	0.710	0.81
621_L	625_F	0.710	0.81
672_R	683_T	0.709	0.81
51_N	229_N	0.709	0.81
832_Y	836_F	0.708	0.81
47_I	57_L	0.706	0.81
138_L	235_I	0.706	0.81
142_V	251_T	0.706	0.81
653_A	657_A	0.705	0.80
329_K	632_D	0.705	0.80
589_V	598_A	0.704	0.80
621_L	720_V	0.704	0.80
313_Y	392_L	0.704	0.80
274_Q	279_I	0.704	0.80
142_V	248_A	0.703	0.80
365_R	458_Y	0.703	0.80
739_V	744_S	0.702	0.80
303_F	677_K	0.702	0.80
84_Q	208_D	0.701	0.80
781_Q	861_Q	0.699	0.80
719_D	722_K	0.698	0.80
244_L	247_M	0.698	0.80
495_D	503_L	0.697	0.80
101_Y	247_M	0.697	0.80
56_L	232_K	0.697	0.80
746_I	752_N	0.696	0.80
70_L	75_G	0.694	0.79
332_L	360_K	0.693	0.79
497_A	500_L	0.690	0.79
80_P	83_Y	0.690	0.79
167_N	206_L	0.690	0.79
532_L	700_P	0.688	0.79
80_P	86_L	0.686	0.79
492_K	498_L	0.686	0.79
422_V	430_A	0.686	0.79
797_L	828_L	0.684	0.78
908_F	912_A	0.684	0.78
469_A	472_V	0.684	0.78
518_K	521_D	0.682	0.78
742_K	751_G	0.682	0.78
733_R	737_V	0.680	0.78
672_R	676_R	0.680	0.78
326_W	329_K	0.680	0.78
585_N	589_V	0.680	0.78
121_S	413_E	0.680	0.78
66_S	239_K	0.678	0.78
224_K	260_S	0.678	0.78
646_D	649_E	0.678	0.78
535_V	880_F	0.677	0.78
148_A	168_A	0.677	0.78
108_A	793_T	0.676	0.78
496_I	504_N	0.676	0.78
168_A	171_T	0.676	0.78
732_C	735_K	0.675	0.78
758_L	764_P	0.675	0.78
99_K	153_L	0.675	0.78
60_D	63_A	0.674	0.77
678_I	681_S	0.674	0.77
604_V	620_L	0.674	0.77
373_F	455_R	0.674	0.77
500_L	506_Y	0.674	0.77
323_L	371_A	0.673	0.77
371_A	374_S	0.673	0.77
261_K	264_E	0.673	0.77
121_S	416_A	0.672	0.77
588_S	592_I	0.671	0.77
166_V	201_G	0.671	0.77
380_R	443_K	0.670	0.77
172_M	800_A	0.670	0.77
52_G	55_V	0.669	0.77
57_L	235_I	0.667	0.77
386_K	439_A	0.667	0.77
862_M	893_I	0.666	0.77
162_E	799_Y	0.666	0.77
307_T	445_R	0.666	0.77
68_S	71_V	0.664	0.76
629_A	684_L	0.663	0.76
572_N	575_L	0.662	0.76
513_L	516_S	0.662	0.76
123_A	126_R	0.661	0.76
492_K	495_D	0.661	0.76
290_L	358_T	0.661	0.76
234_V	416_A	0.660	0.76
275_K	282_V	0.659	0.76
514_I	709_T	0.659	0.76
572_N	690_Y	0.658	0.76
227_S	258_K	0.658	0.76
741_K	750_A	0.657	0.76
825_P	829_W	0.656	0.75
89_Y	93_M	0.655	0.75
333_V	368_V	0.654	0.75
201_G	792_R	0.654	0.75
219_K	222_H	0.653	0.75
606_A	620_L	0.652	0.75
56_L	419_M	0.652	0.75
89_Y	206_L	0.651	0.75
277_I	480_K	0.648	0.75
656_Q	665_S	0.648	0.75
596_T	604_V	0.648	0.75
69_A	130_Y	0.648	0.75
499_S	506_Y	0.645	0.74
658_I	815_G	0.644	0.74
508_P	513_L	0.644	0.74
122_T	201_G	0.642	0.74
739_V	742_K	0.642	0.74
744_S	750_A	0.641	0.74
302_K	305_S	0.640	0.74
192_A	196_S	0.640	0.74
340_S	349_G	0.639	0.74
459_I	463_E	0.639	0.74
108_A	112_K	0.638	0.73
266_T	269_V	0.638	0.73
68_S	74_V	0.637	0.73
715_T	719_D	0.637	0.73
800_A	819_Q	0.637	0.73
746_I	753_S	0.637	0.73
564_R	681_S	0.636	0.73
96_M	105_D	0.636	0.73
119_N	127_T	0.635	0.73
242_P	246_K	0.635	0.73
494_A	503_L	0.635	0.73
402_Y	607_N	0.634	0.73
855_Q	859_I	0.634	0.73
268_P	271_T	0.634	0.73
641_Y	645_M	0.634	0.73
105_D	796_Q	0.634	0.73
166_V	792_R	0.633	0.73
113_M	117_S	0.633	0.73
747_F	752_N	0.632	0.73
484_Q	489_W	0.632	0.73
122_T	127_T	0.632	0.73
92_H	95_L	0.632	0.73
583_L	590_G	0.631	0.73
183_Q	198_F	0.631	0.73
268_P	273_A	0.629	0.72
310_L	389_F	0.629	0.72
82_A	477_Q	0.629	0.72
814_M	913_V	0.628	0.72
97_G	120_A	0.628	0.72
492_K	499_S	0.628	0.72
224_K	262_K	0.628	0.72
613_L	617_F	0.628	0.72
337_S	354_S	0.627	0.72
777_S	893_I	0.627	0.72
867_Q	872_E	0.626	0.72
481_I	486_F	0.625	0.72
771_T	900_L	0.625	0.72
319_S	325_D	0.625	0.72
554_L	702_F	0.625	0.72
242_P	245_A	0.622	0.72
618_Q	719_D	0.622	0.72
450_T	453_N	0.620	0.71
583_L	594_F	0.620	0.71
302_K	306_K	0.620	0.71
637_A	641_Y	0.620	0.71
572_N	577_G	0.619	0.71
671_S	674_E	0.619	0.71
327_L	368_V	0.618	0.71
96_M	108_A	0.617	0.71
107_L	131_L	0.617	0.71
711_A	830_E	0.617	0.71
98_S	149_I	0.616	0.71
816_F	819_Q	0.615	0.71
93_M	158_Y	0.615	0.71
479_D	483_A	0.615	0.71
496_I	499_S	0.615	0.71
862_M	894_V	0.615	0.71
267_V	270_V	0.614	0.71
538_P	709_T	0.614	0.71
123_A	128_A	0.613	0.70
448_M	461_P	0.612	0.70
539_S	869_L	0.612	0.70
652_K	657_A	0.612	0.70
500_L	508_P	0.612	0.70
730_E	733_R	0.612	0.70
494_A	510_D	0.611	0.70
879_D	889_S	0.610	0.70
424_V	430_A	0.610	0.70
307_T	310_L	0.609	0.70
192_A	195_G	0.609	0.70
322_T	329_K	0.609	0.70
250_D	699_R	0.609	0.70
68_S	131_L	0.609	0.70
318_R	325_D	0.608	0.70
535_V	539_S	0.608	0.70
866_P	875_K	0.608	0.70
98_S	168_A	0.608	0.70
268_P	272_D	0.608	0.70
740_D	743_Q	0.607	0.70
278_I	281_Y	0.607	0.70
227_S	257_N	0.606	0.70
118_H	168_A	0.606	0.70
422_V	429_D	0.606	0.70
877_S	882_R	0.606	0.70
495_D	502_E	0.605	0.69
473_D	484_Q	0.604	0.69
831_R	838_T	0.603	0.69
625_F	723_Q	0.603	0.69
471_F	476_Y	0.603	0.69
453_N	458_Y	0.602	0.69
150_A	222_H	0.602	0.69
824_Q	836_F	0.602	0.69
736_D	744_S	0.602	0.69
117_S	121_S	0.600	0.69
221_F	226_Y	0.600	0.69
107_L	111_L	0.600	0.69
177_D	180_R	0.600	0.69
454_A	458_Y	0.600	0.69
384_I	439_A	0.600	0.69
383_G	443_K	0.599	0.69
589_V	596_T	0.598	0.69
677_K	680_P	0.598	0.69
105_D	785_P	0.598	0.69
652_K	665_S	0.597	0.68
730_E	737_V	0.596	0.68
704_V	708_M	0.596	0.68
710_E	714_T	0.595	0.68
170_L	174_R	0.595	0.68
469_A	474_A	0.595	0.68
459_I	462_K	0.594	0.68
695_K	699_R	0.594	0.68
269_V	272_D	0.594	0.68
167_N	170_L	0.594	0.68
529_E	534_V	0.593	0.68
454_A	457_W	0.593	0.68
68_S	138_L	0.593	0.68
172_M	819_Q	0.592	0.68
332_L	341_D	0.592	0.68
779_L	900_L	0.592	0.68
127_T	221_F	0.592	0.68
633_Q	637_A	0.591	0.68
83_Y	187_E	0.591	0.68
828_L	838_T	0.591	0.68
839_A	846_M	0.590	0.68
231_M	255_V	0.590	0.68
103_Q	106_S	0.589	0.67
891_D	894_V	0.589	0.67
97_G	201_G	0.588	0.67
500_L	504_N	0.588	0.67
828_L	831_R	0.588	0.67
778_L	855_Q	0.588	0.67
673_D	682_I	0.587	0.67
527_V	714_T	0.587	0.67
288_K	358_T	0.585	0.67
855_Q	898_K	0.585	0.67
518_K	525_L	0.585	0.67
757_A	764_P	0.585	0.67
791_L	828_L	0.584	0.67
440_K	443_K	0.584	0.67
315_I	319_S	0.583	0.67
308_D	449_M	0.583	0.67
610_T	707_N	0.583	0.67
690_Y	694_L	0.582	0.67
451_P	454_A	0.582	0.67
92_H	166_V	0.582	0.67
54_V	73_P	0.582	0.67
711_A	876_L	0.582	0.67
816_F	828_L	0.581	0.66
390_D	394_N	0.581	0.66
104_A	118_H	0.581	0.66
729_S	733_R	0.580	0.66
85_G	97_G	0.579	0.66
735_K	738_V	0.579	0.66
284_A	464_P	0.578	0.66
845_A	906_A	0.578	0.66
335_G	340_S	0.578	0.66
320_P	325_D	0.577	0.66
747_F	753_S	0.577	0.66
495_D	500_L	0.576	0.66
847_K	902_P	0.576	0.66
142_V	233_A	0.575	0.66
568_M	571_L	0.575	0.66
613_L	716_L	0.575	0.66
647_S	650_K	0.574	0.65
473_D	477_Q	0.574	0.65
471_F	477_Q	0.573	0.65
478_V	482_S	0.572	0.65
875_K	879_D	0.572	0.65
193_H	196_S	0.572	0.65
774_A	858_V	0.571	0.65
662_Q	665_S	0.571	0.65
336_I	339_N	0.570	0.65
517_E	525_L	0.570	0.65
433_I	436_R	0.569	0.65
274_Q	281_Y	0.569	0.65
342_P	802_F	0.569	0.65
121_S	124_P	0.569	0.65
274_Q	282_V	0.568	0.65
763_V	833_K	0.568	0.65
816_F	836_F	0.568	0.65
179_M	190_N	0.567	0.65
655_E	658_I	0.567	0.65
179_M	187_E	0.567	0.65
508_P	512_S	0.567	0.65
783_V	803_A	0.566	0.64
227_S	260_S	0.566	0.64
106_S	144_R	0.566	0.64
587_A	596_T	0.566	0.64
384_I	443_K	0.566	0.64
412_V	417_D	0.565	0.64
434_A	438_D	0.565	0.64
68_S	77_L	0.564	0.64
630_T	633_Q	0.564	0.64
56_L	234_V	0.563	0.64
327_L	330_Q	0.563	0.64
278_I	282_V	0.563	0.64
496_I	501_P	0.563	0.64
51_N	75_G	0.563	0.64
170_L	206_L	0.562	0.64
273_A	277_I	0.562	0.64
746_I	754_T	0.561	0.64
315_I	376_L	0.561	0.64
262_K	265_I	0.560	0.64
467_K	470_Y	0.560	0.64
561_D	690_Y	0.560	0.64
105_D	793_T	0.559	0.63
208_D	473_D	0.559	0.63
246_K	837_P	0.559	0.63
765_T	776_S	0.559	0.63
311_I	325_D	0.558	0.63
419_M	427_T	0.558	0.63
314_L	437_Y	0.558	0.63
162_E	166_V	0.557	0.63
194_P	265_I	0.556	0.63
458_Y	462_K	0.556	0.63
235_I	244_L	0.556	0.63
73_P	77_L	0.556	0.63
824_Q	835_F	0.556	0.63
181_M	281_Y	0.556	0.63
735_K	744_S	0.556	0.63
537_A	540_R	0.555	0.63
506_Y	511_F	0.555	0.63
106_S	140_G	0.555	0.63
478_V	490_Q	0.555	0.63
526_I	534_V	0.554	0.63
651_G	654_F	0.554	0.63
909_F	912_A	0.554	0.63
510_D	514_I	0.553	0.63
776_S	912_A	0.553	0.63
74_V	78_E	0.553	0.63
393_A	397_D	0.552	0.62
679_L	683_T	0.552	0.62
835_F	840_E	0.552	0.62
165_A	788_Y	0.552	0.62
594_F	620_L	0.552	0.62
311_I	446_L	0.552	0.62
96_M	118_H	0.551	0.62
897_I	901_T	0.551	0.62
146_A	254_R	0.550	0.62
757_A	763_V	0.550	0.62
482_S	486_F	0.549	0.62
97_G	119_N	0.549	0.62
140_G	143_D	0.548	0.62
787_F	835_F	0.548	0.62
145_L	170_L	0.547	0.62
120_A	127_T	0.547	0.62
164_N	203_L	0.547	0.62
497_A	501_P	0.546	0.62
50_D	256_P	0.546	0.62
671_S	678_I	0.546	0.62
347_N	350_V	0.546	0.62
738_V	741_K	0.546	0.62
139_P	143_D	0.546	0.62
761_V	764_P	0.545	0.61
770_Y	774_A	0.544	0.61
96_M	148_A	0.544	0.61
886_R	892_K	0.544	0.61
412_V	418_T	0.543	0.61
98_S	173_A	0.543	0.61
92_H	201_G	0.543	0.61
790_Q	831_R	0.543	0.61
537_A	872_E	0.543	0.61
107_L	110_Y	0.542	0.61
576_A	623_G	0.542	0.61
721_Q	725_G	0.542	0.61
529_E	718_R	0.541	0.61
536_Y	713_A	0.541	0.61
899_L	903_Q	0.540	0.61
474_A	478_V	0.539	0.61
494_A	501_P	0.539	0.61
560_M	699_R	0.538	0.61
48_R	51_N	0.538	0.61
751_G	755_D	0.537	0.60
326_W	378_L	0.537	0.60
176_R	180_R	0.537	0.60
791_L	831_R	0.537	0.60
100_K	250_D	0.537	0.60
310_L	321_G	0.536	0.60
672_R	680_P	0.536	0.60
322_T	330_Q	0.535	0.60
139_P	239_K	0.535	0.60
229_N	258_K	0.534	0.60
316_G	320_P	0.534	0.60
454_A	461_P	0.534	0.60
541_Y	872_E	0.533	0.60
314_L	322_T	0.533	0.60
742_K	748_E	0.533	0.60
188_T	455_R	0.532	0.60
576_A	629_A	0.531	0.60
206_L	791_L	0.531	0.60
359_D	364_N	0.531	0.60
683_T	704_V	0.531	0.60
315_I	321_G	0.529	0.59
85_G	119_N	0.529	0.59
504_N	510_D	0.529	0.59
89_Y	95_L	0.529	0.59
844_R	851_F	0.528	0.59
165_A	793_T	0.528	0.59
51_N	57_L	0.527	0.59
519_K	522_H	0.527	0.59
520_Y	524_E	0.526	0.59
81_E	204_E	0.526	0.59
109_E	379_L	0.526	0.59
759_A	832_Y	0.525	0.59
530_S	718_R	0.525	0.59
111_L	116_G	0.525	0.59
467_K	471_F	0.525	0.59
65_K	166_V	0.524	0.59
653_A	658_I	0.523	0.58
840_E	909_F	0.523	0.58
48_R	52_G	0.523	0.58
159_A	162_E	0.523	0.58
714_T	717_A	0.523	0.58
763_V	766_G	0.522	0.58
97_G	122_T	0.521	0.58
437_Y	442_V	0.521	0.58
450_T	454_A	0.521	0.58
504_N	608_G	0.521	0.58
485_T	490_Q	0.520	0.58
315_I	318_R	0.520	0.58
602_L	699_R	0.520	0.58
355_A	359_D	0.519	0.58
634_L	682_I	0.519	0.58
552_L	559_A	0.519	0.58
310_L	320_P	0.519	0.58
512_S	515_K	0.518	0.58
123_A	413_E	0.518	0.58
339_N	351_L	0.518	0.58
201_G	799_Y	0.518	0.58
757_A	765_T	0.517	0.58
566_Q	571_L	0.517	0.58
731_W	735_K	0.516	0.57
583_L	623_G	0.516	0.57
778_L	851_F	0.516	0.57
499_S	505_P	0.516	0.57
316_G	339_N	0.515	0.57
494_A	506_Y	0.515	0.57
483_A	488_D	0.515	0.57
170_L	202_N	0.515	0.57
862_M	866_P	0.514	0.57
535_V	540_R	0.514	0.57
661_A	665_S	0.514	0.57
291_R	352_A	0.514	0.57
80_P	194_P	0.513	0.57
565_N	689_A	0.513	0.57
678_I	683_T	0.513	0.57
366_D	484_Q	0.512	0.57
573_D	602_L	0.511	0.57
127_T	166_V	0.511	0.57
341_D	354_S	0.511	0.57
569_F	573_D	0.511	0.57
906_A	910_H	0.510	0.56
840_E	845_A	0.510	0.56
675_R	681_S	0.510	0.56
521_D	527_V	0.510	0.56
798_G	818_L	0.509	0.56
873_A	877_S	0.509	0.56
497_A	506_Y	0.509	0.56
90_L	165_A	0.508	0.56
558_K	569_F	0.508	0.56
915_E	918_G	0.508	0.56
500_L	505_P	0.508	0.56
456_I	461_P	0.508	0.56
88_H	201_G	0.508	0.56
148_A	152_P	0.507	0.56
518_K	522_H	0.506	0.56
737_V	740_D	0.505	0.56
78_E	225_Y	0.505	0.56
553_I	603_M	0.504	0.56
318_R	336_I	0.504	0.56
83_Y	159_A	0.504	0.56
833_K	920_A	0.504	0.56
341_D	350_V	0.503	0.55
572_N	578_L	0.503	0.55
108_A	111_L	0.502	0.55
45_Q	240_P	0.502	0.55
90_L	93_M	0.502	0.55
145_L	818_L	0.502	0.55
580_L	589_V	0.501	0.55
304_R	448_M	0.501	0.55
654_F	815_G	0.501	0.55
674_E	677_K	0.501	0.55
729_S	742_K	0.500	0.55
564_R	678_I	0.500	0.55
397_D	405_I	0.500	0.55
330_Q	371_A	0.500	0.55
235_I	254_R	0.500	0.55
526_I	714_T	0.500	0.55
481_I	485_T	0.500	0.55
522_H	525_L	0.500	0.55

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1q2lA	1	0.973	100	0.235	Contact Map
3cwwA	3	0.9699	100	0.276	Contact Map
2fgeA	1	0.9272	100	0.411	Contact Map
4l3tA	1	0.8794	100	0.422	Contact Map
3s5mA	1	0.9252	100	0.451	Contact Map
3eoqA	2	0.4189	100	0.634	Contact Map
3amiA	2	0.4304	100	0.639	Contact Map
4nnzA	2	0.4044	100	0.646	Contact Map
1hr6B	1	0.4439	100	0.654	Contact Map
4xeaA	2	0.4231	100	0.657	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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