GREMLIN Database
PNP - Polyribonucleotide nucleotidyltransferase
UniProt: P05055 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG10743
Length: 711 (688)
Sequences: 2515 (1144)
Seq/√Len: 43.6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
253_R276_E5.1411.00
183_E220_N4.7001.00
560_I568_V4.6911.00
354_A449_A4.6331.00
536_V539_Q4.5921.00
320_E323_M4.3561.00
654_I666_L4.0691.00
22_M330_R3.9831.00
459_A500_D3.8131.00
628_K671_E3.6181.00
322_D528_G3.5711.00
350_A431_I3.4421.00
42_V115_A3.2111.00
626_T673_P3.1851.00
626_T671_E3.1551.00
247_A303_N3.1131.00
156_Y174_K3.1011.00
161_Y203_G3.0871.00
332_G452_D2.9021.00
479_S529_A2.8851.00
42_V133_G2.8671.00
327_L536_V2.8401.00
311_A474_N2.7801.00
499_R538_E2.7481.00
211_Q214_V2.7021.00
597_I609_I2.7001.00
166_T169_E2.6681.00
8_K15_T2.6401.00
464_I479_S2.6371.00
499_R535_G2.6271.00
571_K574_S2.5921.00
244_A248_A2.5571.00
157_I162_V2.5121.00
250_A277_T2.4981.00
649_V654_I2.4921.00
254_L270_V2.4651.00
158_N172_E2.4551.00
324_I479_S2.3901.00
156_Y200_Q2.3681.00
556_H605_A2.3641.00
415_M425_V2.3601.00
630_T646_E2.3461.00
543_A546_G2.3281.00
262_D265_E2.3221.00
374_D408_K2.3191.00
139_S223_V2.3011.00
411_V446_A2.2841.00
610_R614_E2.2531.00
7_R225_E2.2361.00
352_V445_G2.2351.00
620_E623_R2.2221.00
578_A582_E2.2051.00
114_I393_V2.2011.00
417_D420_K2.1881.00
689_I693_T2.1351.00
667_Q670_Q2.1301.00
16_V35_M2.1211.00
602_G606_K2.1070.99
630_T640_A2.0950.99
25_R433_E2.0950.99
524_N528_G2.0930.99
245_R284_E2.0920.99
559_K594_T2.0900.99
516_K520_Q2.0630.99
36_D121_N2.0470.99
123_Q168_D2.0470.99
76_S79_R2.0420.99
140_L226_A2.0320.99
217_Q221_E2.0000.99
154_V163_L1.9830.99
609_I613_E1.9770.99
676_V685_I1.9770.99
179_V208_G1.9710.99
558_I609_I1.9680.99
678_E686_R1.9580.99
329_V540_A1.9430.99
527_K531_L1.9340.99
18_L33_V1.9330.99
33_V133_G1.9100.99
582_E611_R1.9020.99
654_I659_V1.9010.99
336_R551_F1.9010.99
447_S460_A1.8980.99
606_K609_I1.8960.99
39_A335_P1.8930.99
18_L132_I1.8830.99
447_S538_E1.8800.99
28_T142_G1.8740.99
475_Y521_V1.8660.99
160_Q169_E1.8510.99
183_E217_Q1.8500.99
116_T385_Y1.8460.99
252_A256_D1.8390.99
619_I676_V1.8390.99
607_H610_R1.8340.99
275_S279_A1.8310.98
310_L474_N1.8280.98
639_V649_V1.8270.98
653_Q691_E1.8180.98
452_D545_R1.8180.98
186_V205_V1.8060.98
584_G604_K1.8050.98
155_G173_S1.8010.98
146_N512_E1.8000.98
249_L280_T1.7700.98
358_T598_A1.7660.98
269_Q272_V1.7630.98
460_A538_E1.7610.98
321_K476_V1.7530.98
414_V457_I1.7500.98
8_K17_T1.7390.98
23_M432_T1.7380.98
197_S200_Q1.7360.98
410_G504_A1.7270.98
7_R221_E1.7160.98
661_K664_D1.7110.98
649_V666_L1.6860.97
307_S311_A1.6810.97
567_D615_I1.6760.97
352_V427_V1.6700.97
10_Q15_T1.6610.97
99_I138_L1.6570.97
154_V207_F1.6550.97
459_A499_R1.6530.97
31_V136_A1.6510.97
156_Y161_Y1.6490.97
354_A427_V1.6450.97
391_G394_G1.6450.97
672_V689_I1.6420.97
206_V516_K1.6380.97
324_I532_H1.6300.97
268_A272_V1.6270.97
132_I215_V1.6050.97
39_A334_L1.5980.96
353_T430_E1.5980.96
554_R599_A1.5920.96
634_D663_T1.5880.96
651_I662_V1.5790.96
272_V276_E1.5760.96
329_V536_V1.5760.96
185_A513_G1.5730.96
18_L136_A1.5630.96
240_E244_A1.5480.96
215_V219_I1.5470.96
153_R176_D1.5470.96
7_R222_L1.5460.96
174_K194_Q1.5440.96
247_A251_E1.5410.96
655_A689_I1.5370.96
556_H609_I1.5330.95
34_S37_D1.5240.95
168_D171_K1.5230.95
127_D153_R1.5110.95
558_I597_I1.5080.95
384_P393_V1.4990.95
590_E594_T1.4980.95
617_A623_R1.4940.95
51_K54_Q1.4880.95
354_A453_A1.4880.95
647_G687_L1.4870.95
46_G143_I1.4850.95
606_K610_R1.4840.95
597_I612_I1.4810.95
656_D692_A1.4780.94
181_G212_Q1.4770.94
470_K511_I1.4740.94
163_L207_F1.4720.94
257_A273_I1.4560.94
599_A605_A1.4450.94
538_E542_N1.4410.94
191_S505_L1.4400.94
9_F16_V1.4360.94
607_H611_R1.4330.93
245_R249_L1.4270.93
328_D342_L1.4230.93
631_R684_R1.4220.93
322_D525_Q1.4180.93
46_G107_F1.4170.93
440_M443_V1.4140.93
242_L296_I1.4140.93
10_Q13_Q1.4100.93
680_D684_R1.4020.93
414_V461_V1.4020.93
324_I464_I1.3980.93
253_R256_D1.3980.93
688_S691_E1.3980.93
6_V17_T1.3970.93
532_H536_V1.3900.92
46_G231_W1.3800.92
131_M149_I1.3760.92
571_K575_V1.3730.92
640_A646_E1.3720.92
136_A222_L1.3710.92
632_I662_V1.3710.92
142_G231_W1.3550.91
641_I685_I1.3480.91
378_F446_A1.3470.91
33_V129_V1.3440.91
575_V615_I1.3430.91
624_V692_A1.3420.91
599_A604_K1.3390.91
107_F111_V1.3370.91
378_F442_S1.3370.91
14_H35_M1.3280.91
115_A130_A1.3140.90
583_T611_R1.3140.90
595_V612_I1.3140.90
139_S219_I1.3130.90
583_T607_H1.3130.90
175_L196_L1.3130.90
107_F231_W1.3100.90
105_E302_K1.2930.89
199_D520_Q1.2890.89
161_Y200_Q1.2870.89
351_L432_T1.2840.89
278_I294_G1.2650.88
536_V540_A1.2590.88
619_I641_I1.2590.88
362_A373_T1.2550.88
197_S502_I1.2520.88
337_T353_T1.2450.87
35_M129_V1.2450.87
316_I484_D1.2390.87
68_Y428_V1.2380.87
32_M118_V1.2370.87
18_L31_V1.2290.87
131_M151_A1.2280.87
239_N292_E1.2250.87
601_D604_K1.2220.86
61_V95_I1.2130.86
376_F446_A1.2040.86
350_A441_A1.2020.86
649_V692_A1.2010.85
120_V126_P1.2010.85
535_G539_Q1.1980.85
631_R668_M1.1970.85
99_I134_A1.1960.85
451_M457_I1.1930.85
17_T34_S1.1930.85
603_E607_H1.1910.85
168_D172_E1.1910.85
28_T45_V1.1880.85
43_T384_P1.1880.85
313_E474_N1.1850.85
568_V595_V1.1830.85
274_K294_G1.1800.84
659_V664_D1.1790.84
350_A445_G1.1750.84
223_V227_G1.1660.84
106_G233_W1.1660.84
229_P232_D1.1620.84
64_Q88_E1.1570.83
267_Y271_D1.1530.83
243_N247_A1.1530.83
580_T585_T1.1510.83
461_V498_S1.1490.83
524_N527_K1.1440.83
250_A273_I1.1420.82
142_G230_R1.1400.82
189_V507_M1.1390.82
106_G235_P1.1360.82
260_I269_Q1.1340.82
151_A180_A1.1300.82
194_Q413_A1.1270.82
640_A643_G1.1270.82
632_I668_M1.1230.81
466_M477_V1.1210.81
46_G111_V1.1200.81
306_R490_D1.1200.81
246_V277_T1.1190.81
651_I661_K1.1150.81
38_T126_P1.1080.80
220_N224_K1.1070.80
385_Y432_T1.1060.80
277_T297_L1.1060.80
174_K200_Q1.1050.80
532_H535_G1.1040.80
142_G228_K1.1020.80
529_A532_H1.1020.80
382_F386_S1.0970.80
18_L222_L1.0920.79
443_V496_A1.0920.79
16_V132_I1.0910.79
603_E606_K1.0900.79
470_K475_Y1.0880.79
199_D524_N1.0870.79
72_R79_R1.0860.79
568_V571_K1.0840.79
273_I276_E1.0820.79
57_F111_V1.0820.79
161_Y207_F1.0810.79
654_I665_Y1.0790.79
429_S445_G1.0710.78
611_R614_E1.0700.78
465_A477_V1.0690.78
87_G91_I1.0650.78
568_V575_V1.0650.78
251_E255_S1.0640.78
249_L281_L1.0630.78
427_V449_A1.0630.78
5_I225_E1.0620.78
201_M502_I1.0620.78
159_D174_K1.0570.77
641_I676_V1.0570.77
199_D203_G1.0560.77
28_T46_G1.0540.77
637_A666_L1.0540.77
255_S259_R1.0520.77
619_I642_G1.0520.77
23_M342_L1.0480.77
457_I460_A1.0460.76
162_V169_E1.0460.76
447_S451_M1.0440.76
195_L459_A1.0410.76
305_V309_V1.0410.76
610_R613_E1.0390.76
375_T418_M1.0390.76
118_V351_L1.0380.76
642_G645_K1.0360.76
20_T136_A1.0330.76
414_V459_A1.0320.75
479_S532_H1.0300.75
19_E34_S1.0280.75
254_L297_L1.0270.75
411_V450_L1.0260.75
30_A43_T1.0240.75
352_V378_F1.0220.75
579_L611_R1.0220.75
357_G361_D1.0190.75
119_S337_T1.0150.74
249_L277_T1.0130.74
254_L304_V1.0110.74
336_R549_S1.0080.74
653_Q690_K0.9990.73
331_T452_D0.9960.73
213_Q217_Q0.9960.73
568_V612_I0.9940.73
448_L452_D0.9880.72
617_A642_G0.9830.72
564_K618_E0.9830.72
310_L476_V0.9820.72
175_L204_A0.9820.72
98_P180_A0.9820.72
54_Q108_V0.9810.72
659_V666_L0.9800.72
304_V307_S0.9800.72
381_N428_V0.9790.72
11_Y16_V0.9750.71
246_V250_A0.9750.71
397_K400_E0.9730.71
18_L218_N0.9710.71
327_L529_A0.9700.71
313_E476_V0.9700.71
547_D602_G0.9680.71
37_D336_R0.9660.71
24_A41_F0.9640.70
40_V115_A0.9640.70
364_V373_T0.9630.70
433_E438_S0.9630.70
333_V342_L0.9610.70
39_A337_T0.9610.70
341_A431_I0.9600.70
654_I662_V0.9600.70
208_G211_Q0.9580.70
32_M39_A0.9580.70
448_L541_I0.9560.70
362_A424_T0.9550.70
359_A362_A0.9540.70
253_R273_I0.9540.70
245_R248_A0.9530.69
259_R308_R0.9530.69
627_G639_V0.9510.69
585_T604_K0.9500.69
555_I598_A0.9500.69
115_A133_G0.9500.69
218_N222_L0.9490.69
632_I666_L0.9460.69
258_Y304_V0.9450.69
289_D292_E0.9440.69
46_G142_G0.9440.69
655_A659_V0.9410.68
110_E392_M0.9410.68
568_V615_I0.9400.68
334_L353_T0.9390.68
54_Q57_F0.9340.68
62_N89_T0.9320.68
115_A134_A0.9320.68
673_P692_A0.9300.68
421_F456_P0.9300.68
579_L585_T0.9290.67
29_A44_V0.9270.67
237_P240_E0.9240.67
195_L500_D0.9230.67
621_V678_E0.9220.67
9_F218_N0.9220.67
541_I545_R0.9210.67
299_A302_K0.9200.67
331_T541_I0.9150.66
633_V638_F0.9120.66
20_T226_A0.9110.66
63_Y130_A0.9100.66
558_I612_I0.9090.66
578_A611_R0.9090.66
192_E409_R0.9080.66
462_A531_L0.9070.66
374_D405_R0.9060.66
156_Y175_L0.9050.65
210_E213_Q0.9040.65
577_R581_E0.9000.65
558_I595_V0.8990.65
66_R430_E0.8960.65
68_Y430_E0.8960.65
649_V689_I0.8940.64
112_Q390_T0.8930.64
313_E321_K0.8920.64
242_L246_V0.8920.64
95_I115_A0.8860.64
567_D575_V0.8860.64
407_A443_V0.8830.64
92_A616_T0.8810.63
23_M39_A0.8800.63
561_N618_E0.8800.63
63_Y88_E0.8780.63
198_E527_K0.8780.63
189_V465_A0.8770.63
27_A45_V0.8760.63
46_G109_N0.8760.63
274_K297_L0.8760.63
195_L414_V0.8740.63
657_K660_E0.8730.63
227_G230_R0.8720.63
238_V243_N0.8670.62
331_T540_A0.8660.62
88_E378_F0.8640.62
44_V133_G0.8630.62
280_T284_E0.8630.62
145_F148_P0.8620.62
240_E243_N0.8600.61
157_I172_E0.8580.61
329_V448_L0.8580.61
517_E521_V0.8560.61
213_Q216_I0.8500.61
245_R281_L0.8500.61
688_S692_A0.8500.61
462_A538_E0.8500.61
386_S438_S0.8500.61
447_S537_M0.8480.60
40_V95_I0.8480.60
627_G687_L0.8470.60
220_N223_V0.8460.60
279_A282_L0.8460.60
127_D178_V0.8450.60
255_S312_G0.8450.60
214_V217_Q0.8410.60
579_L608_A0.8410.60
185_A189_V0.8390.60
427_V446_A0.8380.59
150_G514_I0.8370.59
639_V654_I0.8360.59
387_V391_G0.8350.59
627_G647_G0.8350.59
557_T594_T0.8350.59
141_S230_R0.8350.59
91_I125_N0.8340.59
44_V137_A0.8340.59
247_A300_I0.8320.59
57_F109_N0.8320.59
278_I282_L0.8310.59
83_R89_T0.8270.58
554_R604_K0.8270.58
243_N296_I0.8260.58
666_L672_V0.8240.58
659_V662_V0.8230.58
262_D347_E0.8230.58
640_A644_G0.8220.58
656_D693_T0.8220.58
192_E405_R0.8220.58
272_V275_S0.8220.58
217_Q220_N0.8210.58
327_L532_H0.8200.58
629_V666_L0.8180.58
529_A536_V0.8180.58
37_D550_E0.8170.57
568_V616_T0.8160.57
560_I587_I0.8150.57
452_D541_I0.8150.57
559_K592_D0.8150.57
331_T545_R0.8080.57
676_V679_V0.8050.56
105_E653_Q0.8040.56
161_Y204_A0.8030.56
256_D269_Q0.8020.56
675_K690_K0.8010.56
121_N124_V0.8010.56
298_H301_E0.8010.56
633_V668_M0.8000.56
259_R312_G0.7990.56
352_V431_I0.7990.56
260_I265_E0.7970.56
515_T518_I0.7960.55
14_H169_E0.7960.55
209_H213_Q0.7950.55
384_P395_S0.7940.55
628_K640_A0.7940.55
548_I554_R0.7930.55
261_T265_E0.7930.55
265_E268_A0.7910.55
631_R686_R0.7910.55
73_I377_L0.7910.55
354_A445_G0.7900.55
344_T433_E0.7900.55
364_V371_E0.7900.55
83_R395_S0.7900.55
688_S693_T0.7890.55
200_Q203_G0.7880.55
11_Y215_V0.7880.55
20_T31_V0.7880.55
637_A662_V0.7870.55
377_L415_M0.7840.54
420_K458_K0.7840.54
42_V134_A0.7830.54
206_V520_Q0.7820.54
128_I132_I0.7810.54
177_L196_L0.7790.54
376_F412_L0.7790.54
309_V469_V0.7780.54
31_V222_L0.7760.54
45_V112_Q0.7730.53
150_G207_F0.7720.53
44_V143_I0.7690.53
352_V376_F0.7680.53
250_A281_L0.7670.53
649_V672_V0.7670.53
62_N92_A0.7640.52
14_H124_V0.7640.52
561_N567_D0.7640.52
221_E225_E0.7610.52
22_M32_M0.7600.52
327_L535_G0.7550.52
579_L583_T0.7540.51
105_E298_H0.7540.51
279_A283_A0.7540.51
635_F648_L0.7530.51
111_V231_W0.7490.51
421_F455_V0.7480.51
341_A448_L0.7470.51
250_A253_R0.7470.51
405_R408_K0.7440.51
248_A252_A0.7440.51
267_Y387_V0.7420.50
135_S148_P0.7420.50
276_E280_T0.7420.50
33_V40_V0.7420.50
26_Q433_E0.7410.50
160_Q232_D0.7390.50
64_Q114_I0.7390.50
57_F108_V0.7390.50
359_A424_T0.7380.50
255_S304_V0.7370.50
635_F646_E0.7360.50
415_M450_L0.7360.50
25_R344_T0.7330.49
457_I682_Q0.7310.49
239_N289_D0.7300.49
206_V210_E0.7280.49
30_A41_F0.7280.49
565_I589_I0.7280.49
521_V525_Q0.7260.49
23_M351_L0.7260.49
184_A512_E0.7260.49
427_V457_I0.7260.49
153_R440_M0.7260.49
407_A440_M0.7250.49
285_D293_L0.7240.49
448_L584_G0.7230.49
12_G16_V0.7220.48
678_E681_R0.7210.48
47_Q54_Q0.7210.48
276_E279_A0.7210.48
571_K595_V0.7190.48
118_V430_E0.7190.48
257_A270_V0.7180.48
205_V519_M0.7180.48
350_A378_F0.7180.48
564_K567_D0.7170.48
452_D583_T0.7170.48
475_Y517_E0.7160.48
265_E269_Q0.7160.48
50_A109_N0.7150.48
87_G125_N0.7140.48
210_E516_K0.7140.48
466_M507_M0.7130.48
77_F364_V0.7130.48
635_F638_F0.7120.47
653_Q677_L0.7110.47
587_I612_I0.7110.47
558_I616_T0.7090.47
295_E298_H0.7090.47
585_T599_A0.7070.47
50_A54_Q0.7060.47
33_V132_I0.7060.47
43_T114_I0.7050.47
244_A247_A0.7050.47
189_V505_L0.7040.47
451_M541_I0.7030.47
198_E530_R0.7030.47
92_A397_K0.7020.47
35_M124_V0.7010.46
20_T222_L0.7010.46
556_H597_I0.7010.46
152_A215_V0.7010.46
36_D124_V0.7010.46
298_H487_H0.6990.46
447_S457_I0.6990.46
77_F366_D0.6970.46
78_F86_E0.6960.46
627_G646_E0.6960.46
662_V665_Y0.6960.46
212_Q216_I0.6950.46
64_Q396_P0.6950.46
79_R85_S0.6930.46
274_K298_H0.6930.46
324_I536_V0.6930.46
10_Q14_H0.6930.46
450_L455_V0.6900.45
475_Y518_I0.6900.45
465_A488_L0.6890.45
466_M526_A0.6880.45
308_R312_G0.6870.45
654_I672_V0.6870.45
243_N299_A0.6870.45
152_A163_L0.6860.45
283_A286_E0.6860.45
427_V450_L0.6850.45
91_I127_D0.6820.45
153_R178_V0.6820.45
292_E296_I0.6820.45
362_A418_M0.6810.45
140_L143_I0.6800.44
202_L523_L0.6790.44
195_L498_S0.6780.44
583_T587_I0.6770.44
309_V316_I0.6760.44
112_Q393_V0.6750.44
556_H606_K0.6750.44
255_S308_R0.6740.44
114_I384_P0.6740.44
149_I273_I0.6730.44
136_A219_I0.6730.44
614_E617_A0.6730.44
677_L686_R0.6710.44
375_T424_T0.6710.44
580_T595_V0.6700.43
44_V134_A0.6690.43
627_G651_I0.6690.43
495_V522_A0.6690.43
132_I136_A0.6690.43
620_E625_Y0.6670.43
250_A254_L0.6670.43
63_Y126_P0.6670.43
241_A244_A0.6670.43
575_V578_A0.6660.43
499_R531_L0.6650.43
151_A205_V0.6630.43
624_V675_K0.6630.43
112_Q392_M0.6630.43
658_R664_D0.6620.43
72_R77_F0.6610.43
451_M545_R0.6600.43
149_I180_A0.6580.42
106_G292_E0.6580.42
560_I565_I0.6570.42
466_M525_Q0.6560.42
16_V218_N0.6560.42
555_I596_K0.6560.42
273_I297_L0.6540.42
377_L424_T0.6540.42
84_P395_S0.6540.42
358_T554_R0.6530.42
566_K571_K0.6530.42
62_N407_A0.6530.42
615_I619_I0.6520.42
637_A664_D0.6510.42
604_K607_H0.6510.42
9_F214_V0.6500.42
585_T611_R0.6490.42
477_V521_V0.6480.41
204_A208_G0.6480.41
64_Q378_F0.6480.41
268_A271_D0.6480.41
49_K294_G0.6470.41
333_V351_L0.6460.41
95_I130_A0.6450.41
31_V137_A0.6440.41
390_T394_G0.6430.41
382_F387_V0.6420.41
624_V673_P0.6420.41
384_P390_T0.6410.41
352_V447_S0.6410.41
637_A665_Y0.6410.41
16_V124_V0.6410.41
256_D259_R0.6400.41
82_G396_P0.6400.41
29_A228_K0.6400.41
601_D606_K0.6390.41
440_M496_A0.6390.41
28_T231_W0.6390.41
142_G227_G0.6380.41
509_I518_I0.6380.41
160_Q203_G0.6380.41
313_E322_D0.6370.40
673_P689_I0.6370.40
296_I300_I0.6350.40
196_L200_Q0.6350.40
617_A625_Y0.6340.40
604_K608_A0.6330.40
205_V208_G0.6320.40
105_E487_H0.6310.40
7_R218_N0.6310.40
583_T608_A0.6300.40
62_N397_K0.6290.40
412_L415_M0.6280.40
128_I178_V0.6280.40
55_D487_H0.6280.40
352_V446_A0.6280.40
157_I173_S0.6270.39
132_I150_G0.6260.39
623_R645_K0.6260.39
599_A602_G0.6250.39
156_Y196_L0.6250.39
170_L176_D0.6250.39
631_R634_D0.6240.39
145_F219_I0.6240.39
152_A181_G0.6240.39
32_M41_F0.6230.39
158_N171_K0.6230.39
520_Q524_N0.6220.39
637_A658_R0.6210.39
515_T519_M0.6200.39
78_F367_E0.6200.39
535_G538_E0.6190.39
175_L200_Q0.6180.39
189_V488_L0.6170.39
62_N392_M0.6170.39
73_I76_S0.6170.39
316_I482_L0.6170.39
212_Q215_V0.6170.39
189_V466_M0.6170.39
259_R314_P0.6160.38
111_V143_I0.6160.38
64_Q116_T0.6160.38
495_V526_A0.6140.38
72_R76_S0.6130.38
29_A137_A0.6120.38
655_A665_Y0.6120.38
384_P391_G0.6090.38
614_E642_G0.6080.38
666_L692_A0.6080.38
87_G92_A0.6080.38
264_Q267_Y0.6070.38
600_T605_A0.6060.38
357_G424_T0.6060.38
675_K688_S0.6060.38
563_D566_K0.6060.38
183_E213_Q0.6050.38
632_I651_I0.6050.38
45_V114_I0.6050.38
271_D275_S0.6040.37
29_A140_L0.6040.37
395_S671_E0.6040.37
78_F686_R0.6040.37
40_V128_I0.6030.37
22_M333_V0.6020.37
580_T588_E0.6010.37
675_K691_E0.6000.37
281_L285_D0.6000.37
549_S552_A0.5990.37
114_I385_Y0.5990.37
109_N231_W0.5990.37
689_I692_A0.5990.37
631_R676_V0.5980.37
136_A140_L0.5980.37
219_I225_E0.5970.37
62_N395_S0.5960.37
117_V387_V0.5940.37
646_E676_V0.5940.37
598_A605_A0.5930.36
392_M682_Q0.5920.36
203_G516_K0.5920.36
378_F431_I0.5910.36
410_G503_S0.5910.36
575_V616_T0.5910.36
524_N531_L0.5900.36
110_E525_Q0.5900.36
517_E520_Q0.5900.36
134_A149_I0.5890.36
12_G211_Q0.5880.36
487_H514_I0.5870.36
135_S150_G0.5870.36
116_T430_E0.5850.36
77_F118_V0.5840.36
396_P401_I0.5830.36
179_V205_V0.5830.36
228_K624_V0.5830.36
614_E643_G0.5820.35
411_V415_M0.5810.35
252_A255_S0.5810.35
221_E224_K0.5800.35
48_K271_D0.5800.35
140_L229_P0.5800.35
550_E554_R0.5800.35
332_G445_G0.5790.35
136_A218_N0.5790.35
451_M538_E0.5790.35
250_A297_L0.5790.35
431_I438_S0.5780.35
410_G496_A0.5770.35
26_Q438_S0.5760.35
655_A685_I0.5760.35
641_I646_E0.5750.35
201_M204_A0.5750.35
13_Q169_E0.5750.35
488_L511_I0.5750.35
45_V442_S0.5750.35
242_L293_L0.5740.35
191_S484_D0.5740.35
584_G599_A0.5730.35
613_E617_A0.5730.35
641_I687_L0.5730.35
179_V409_R0.5720.35
251_E304_V0.5720.35
270_V559_K0.5710.35
509_I515_T0.5710.35
441_A462_A0.5710.35
414_V498_S0.5700.34
5_I221_E0.5690.34
267_Y347_E0.5690.34
671_E686_R0.5680.34
243_N246_V0.5680.34
258_Y305_V0.5680.34
39_A118_V0.5670.34
70_A122_P0.5660.34
525_Q528_G0.5640.34
296_I299_A0.5640.34
238_V299_A0.5640.34
341_A378_F0.5630.34
68_Y353_T0.5620.34
179_V189_V0.5620.34
245_R285_D0.5620.34
531_L535_G0.5620.34
16_V215_V0.5610.34
254_L273_I0.5610.34
44_V89_T0.5610.34
630_T638_F0.5600.34
41_F116_T0.5570.33
619_I645_K0.5570.33
324_I462_A0.5560.33
222_L225_E0.5560.33
51_K105_E0.5560.33
277_T281_L0.5550.33
347_E435_N0.5550.33
657_K665_Y0.5550.33
410_G640_A0.5550.33
427_V453_A0.5550.33
204_A438_S0.5540.33
632_I635_F0.5530.33
99_I149_I0.5530.33
637_A651_I0.5530.33
142_G258_Y0.5530.33
280_T385_Y0.5520.33
470_K473_D0.5520.33
300_I304_V0.5520.33
11_Y152_A0.5510.33
313_E475_Y0.5510.33
68_Y381_N0.5510.33
646_E684_R0.5500.33
666_L670_Q0.5500.33
170_L173_S0.5500.33
192_E412_L0.5490.33
305_V316_I0.5480.33
11_Y132_I0.5480.33
313_E521_V0.5480.33
623_R641_I0.5460.32
119_S562_P0.5460.32
634_D678_E0.5460.32
585_T612_I0.5450.32
42_V92_A0.5450.32
67_T368_L0.5450.32
40_V684_R0.5440.32
28_T43_T0.5440.32
631_R638_F0.5440.32
579_L607_H0.5440.32
77_F628_K0.5430.32
447_S541_I0.5430.32
327_L441_A0.5430.32
440_M554_R0.5430.32
258_Y316_I0.5430.32
386_S565_I0.5420.32
376_F449_A0.5410.32
358_T584_G0.5410.32
88_E92_A0.5410.32
341_A445_G0.5410.32
74_P368_L0.5400.32
375_T415_M0.5400.32
326_G529_A0.5390.32
625_Y648_L0.5390.32
327_L464_I0.5390.32
465_A525_Q0.5390.32
298_H302_K0.5390.32
207_F211_Q0.5390.32
152_A212_Q0.5390.32
159_D200_Q0.5380.32
568_V587_I0.5380.32
350_A429_S0.5380.32
70_A368_L0.5380.32
185_A488_L0.5380.32
91_I149_I0.5380.32
156_Y203_G0.5370.32
154_V161_Y0.5370.32
282_L286_E0.5370.32
544_P548_I0.5370.32
663_T667_Q0.5360.32
328_D536_V0.5350.31
89_T185_A0.5340.31
558_I613_E0.5340.31
378_F433_E0.5340.31
23_M32_M0.5340.31
440_M577_R0.5330.31
408_K412_L0.5330.31
376_F433_E0.5320.31
532_H539_Q0.5320.31
677_L688_S0.5310.31
246_V249_L0.5310.31
405_R412_L0.5300.31
525_Q529_A0.5300.31
45_V116_T0.5300.31
258_Y270_V0.5290.31
159_D575_V0.5290.31
89_T438_S0.5290.31
574_S578_A0.5290.31
629_V637_A0.5280.31
251_E300_I0.5280.31
107_F145_F0.5270.31
445_G448_L0.5260.31
76_S367_E0.5260.31
125_N281_L0.5260.31
189_V519_M0.5260.31
598_A615_I0.5260.31
247_A250_A0.5250.31
653_Q686_R0.5250.31
322_D521_V0.5250.31
484_D686_R0.5250.31
136_A149_I0.5240.31
654_I692_A0.5240.31
603_E610_R0.5240.31
529_A556_H0.5240.31
182_T514_I0.5240.31
369_M372_R0.5230.30
582_E607_H0.5220.30
562_P580_T0.5220.30
161_Y174_K0.5220.30
651_I658_R0.5210.30
623_R692_A0.5210.30
241_A245_R0.5210.30
359_A418_M0.5200.30
60_T110_E0.5200.30
277_T293_L0.5200.30
62_N583_T0.5200.30
318_G479_S0.5190.30
117_V549_S0.5190.30
555_I609_I0.5190.30
358_T424_T0.5180.30
88_E686_R0.5180.30
198_E531_L0.5170.30
360_R588_E0.5160.30
277_T280_T0.5160.30
324_I537_M0.5160.30
83_R419_D0.5150.30
438_S692_A0.5150.30
514_I519_M0.5150.30
224_K272_V0.5150.30
392_M630_T0.5150.30
471_E474_N0.5140.30
15_T36_D0.5140.30
246_V265_E0.5140.30
378_F438_S0.5140.30
88_E352_V0.5130.30
139_S220_N0.5130.30
653_Q688_S0.5120.30
139_S147_G0.5120.30
30_A118_V0.5110.30
27_A30_A0.5100.29
146_N227_G0.5100.29
411_V427_V0.5100.29
341_A354_A0.5100.29
316_I577_R0.5090.29
360_R586_T0.5090.29
24_A43_T0.5090.29
266_R482_L0.5080.29
185_A466_M0.5080.29
460_A499_R0.5070.29
189_V470_K0.5070.29
579_L599_A0.5070.29
239_N242_L0.5070.29
679_V685_I0.5070.29
185_A209_H0.5060.29
347_E484_D0.5060.29
131_M377_L0.5060.29
20_T23_M0.5060.29
112_Q391_G0.5060.29
321_K469_V0.5060.29
577_R615_I0.5060.29
134_A153_R0.5050.29
632_I670_Q0.5050.29
477_V507_M0.5040.29
327_L465_A0.5040.29
132_I218_N0.5040.29
181_G519_M0.5030.29
242_L245_R0.5030.29
567_D616_T0.5030.29
113_V245_R0.5030.29
106_G234_Q0.5030.29
115_A387_V0.5020.29
88_E370_G0.5020.29
323_M613_E0.5020.29
502_I531_L0.5010.29
466_M488_L0.5010.29
34_S39_A0.5010.29
67_T376_F0.5010.29
254_L554_R0.5000.29
482_L488_L0.5000.29
507_M522_A0.5000.29
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4nbqA 3 0.955 100 0.295 Contact Map
3cdiA 3 0.7257 100 0.295 Contact Map
1e3pA 3 0.8692 100 0.325 Contact Map
4aidA 3 0.7975 100 0.334 Contact Map
3u1kA 3 0.8551 100 0.409 Contact Map
3gmeA 3 0.6779 100 0.434 Contact Map
2nn6A 1 0.3797 100 0.799 Contact Map
2nn6B 1 0.3263 100 0.831 Contact Map
2je6B 2 0.3249 100 0.833 Contact Map
2po1A 1 0.3277 100 0.835 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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