PABB - ECOLI - GREMLIN Contacts

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PABB - Aminodeoxychorismate synthase component 1

UniProt:	P05041	Sequences: MKTLSPAVITLLWRQDAAEFYFSRLSHLPWAMLLHSGYADHPYSRFDIVVAEPICTLTTFGKETVVSESEKRTTTTDDPLQVLQQVLDRADIRPTHNEDLPFQGGALGLFGYDLGRRFESLPEIAEQDIVLPDMAVGIYDWALIVDHQRHTVSLLSHNDVNARRAWLESQQFSPQEDFTLTSDWQSNMTREQYGEKFRQVQEYLHSGDCYQVNLAQRFHATYSGDEWQAFLQLNQANRAPFSAFLRLEQGAILSLSPERFILCDNSEIQTRPIKGTLPRLPDPQEDSKQAVKLANSAKDRAENLMIVDLMRNDIGRVAVAGSVKVPELFVVEPFPAVHHLVSTITAQLPEQLHASDLLRAAFPGGSITGAPKVRAMEIIDELEPQRRNAWCGSIGYLSFCGNMDTSITIRTLTAINGQIFCSAGGGIVADSQEEAEYQETFDKVNRILKQLEK	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10683
Length:	453 (433)
Sequences:	5652 (3862)
Seq/√Len:	185.6

ECOLI - PABB TRPE MENF ENTC
BACSU - TRPE PABB MENF DHBC
HALSA - TRPE1 TRPE2 Q9HQN2
SULSO - TRPE

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
318_A	346_A	4.669	1.00
319_V	347_Q	4.238	1.00
84_Q	353_H	4.233	1.00
367_I	391_C	4.042	1.00
190_R	194_G	3.498	1.00
277_L	292_K	3.447	1.00
319_V	350_E	3.361	1.00
326_P	345_T	3.189	1.00
267_E	345_T	3.170	1.00
203_Y	208_D	3.104	1.00
276_T	337_V	2.936	1.00
432_Q	435_A	2.905	1.00
203_Y	381_E	2.864	1.00
219_H	418_Q	2.808	1.00
327_E	330_V	2.793	1.00
194_G	434_E	2.613	1.00
374_R	377_E	2.609	1.00
32_M	50_V	2.608	1.00
193_Y	425_G	2.598	1.00
190_R	434_E	2.524	1.00
395_G	405_T	2.520	1.00
189_T	192_Q	2.508	1.00
78_D	81_Q	2.506	1.00
202_E	206_S	2.404	1.00
324_K	345_T	2.395	1.00
78_D	359_R	2.382	1.00
209_C	212_V	2.376	1.00
287_S	291_V	2.365	1.00
349_P	352_L	2.325	1.00
291_V	295_N	2.309	1.00
290_A	333_P	2.305	1.00
279_R	286_D	2.302	1.00
364_G	407_I	2.279	1.00
219_H	420_F	2.263	1.00
188_M	196_K	2.256	1.00
352_L	356_D	2.228	1.00
221_T	418_Q	2.200	1.00
226_E	251_A	2.195	1.00
112_Y	376_M	2.169	1.00
266_S	347_Q	2.127	1.00
287_S	290_A	2.118	1.00
333_P	338_H	2.101	1.00
200_V	212_V	2.092	1.00
252_I	389_A	2.088	1.00
195_E	198_R	2.073	1.00
243_A	394_I	2.037	1.00
267_E	347_Q	1.958	1.00
314_I	318_A	1.958	1.00
280_L	285_E	1.946	1.00
45_R	146_D	1.940	1.00
259_R	404_D	1.934	1.00
378_I	382_L	1.930	1.00
317_V	360_A	1.926	1.00
331_V	340_L	1.899	1.00
270_T	310_M	1.882	1.00
198_R	201_Q	1.876	1.00
285_E	288_K	1.866	1.00
32_M	107_L	1.837	1.00
211_Q	426_G	1.836	1.00
294_A	340_L	1.826	1.00
243_A	254_S	1.826	1.00
296_S	299_D	1.825	1.00
160_V	163_R	1.824	1.00
22_F	31_A	1.804	1.00
253_L	414_A	1.785	1.00
48_I	144_I	1.782	1.00
283_P	287_S	1.781	1.00
225_D	228_Q	1.777	1.00
414_A	419_I	1.746	1.00
273_I	341_V	1.713	1.00
163_R	166_W	1.711	1.00
332_E	341_V	1.708	1.00
280_L	289_Q	1.697	1.00
434_E	438_Q	1.694	1.00
202_E	205_H	1.686	1.00
271_R	332_E	1.678	1.00
190_R	437_Y	1.653	1.00
21_Y	145_V	1.650	1.00
200_V	214_L	1.634	1.00
106_A	138_I	1.629	1.00
246_R	251_A	1.625	1.00
187_N	385_Q	1.604	1.00
281_P	285_E	1.582	1.00
389_A	408_T	1.571	1.00
209_C	375_A	1.549	1.00
198_R	433_E	1.534	1.00
110_F	114_L	1.533	1.00
216_Q	440_T	1.519	1.00
438_Q	442_D	1.518	1.00
288_K	292_K	1.517	1.00
319_V	349_P	1.517	1.00
358_L	397_L	1.511	1.00
282_D	285_E	1.504	1.00
289_Q	292_K	1.493	1.00
203_Y	374_R	1.492	1.00
197_F	433_E	1.479	1.00
113_D	380_D	1.461	1.00
222_Y	414_A	1.451	1.00
290_A	331_V	1.436	1.00
214_L	425_G	1.436	1.00
437_Y	441_F	1.432	1.00
314_I	346_A	1.399	1.00
199_Q	381_E	1.395	1.00
315_G	321_G	1.394	1.00
203_Y	378_I	1.389	1.00
127_Q	130_V	1.388	1.00
435_A	438_Q	1.384	1.00
254_S	406_S	1.383	1.00
58_T	65_V	1.358	1.00
192_Q	384_P	1.356	1.00
192_Q	195_E	1.351	1.00
304_L	329_F	1.349	1.00
412_L	419_I	1.349	1.00
194_G	198_R	1.345	1.00
264_D	402_N	1.344	1.00
79_P	134_M	1.337	1.00
269_Q	345_T	1.335	1.00
197_F	427_I	1.334	1.00
438_Q	441_F	1.324	1.00
184_W	220_A	1.323	1.00
244_F	251_A	1.309	1.00
199_Q	202_E	1.304	1.00
358_L	405_T	1.302	1.00
23_S	231_L	1.302	1.00
217_R	420_F	1.299	1.00
124_I	380_D	1.294	1.00
271_R	327_E	1.293	1.00
226_E	414_A	1.293	1.00
190_R	438_Q	1.284	1.00
348_L	357_L	1.283	1.00
18_A	145_V	1.280	1.00
243_A	252_I	1.268	1.00
268_I	318_A	1.268	1.00
241_F	259_R	1.266	1.00
220_A	419_I	1.265	1.00
229_A	414_A	1.265	1.00
30_W	56_T	1.263	1.00
194_G	433_E	1.259	1.00
113_D	386_R	1.254	1.00
412_L	447_I	1.251	1.00
185_Q	221_T	1.248	1.00
215_A	422_S	1.246	1.00
396_Y	404_D	1.246	1.00
423_A	444_V	1.240	1.00
398_S	402_N	1.232	1.00
304_L	328_L	1.224	1.00
268_I	314_I	1.213	1.00
374_R	381_E	1.208	1.00
102_F	107_L	1.200	1.00
229_A	412_L	1.194	1.00
425_G	440_T	1.192	1.00
84_Q	88_D	1.179	1.00
35_H	234_N	1.177	1.00
263_C	268_I	1.173	1.00
213_N	424_G	1.172	1.00
284_Q	288_K	1.169	1.00
192_Q	196_K	1.164	1.00
326_P	343_T	1.164	1.00
199_Q	203_Y	1.163	1.00
214_L	427_I	1.156	1.00
269_Q	343_T	1.156	1.00
191_E	195_E	1.154	1.00
212_V	379_I	1.150	1.00
394_I	408_T	1.144	1.00
229_A	253_L	1.138	1.00
221_T	417_G	1.136	1.00
47_D	147_H	1.132	1.00
136_V	405_T	1.130	1.00
263_C	357_L	1.125	1.00
198_R	202_E	1.119	1.00
216_Q	441_F	1.118	1.00
127_Q	386_R	1.117	1.00
263_C	348_L	1.117	1.00
166_W	169_S	1.114	1.00
79_P	117_R	1.112	1.00
208_D	374_R	1.111	1.00
266_S	350_E	1.110	1.00
144_I	155_L	1.109	1.00
226_E	244_F	1.105	1.00
186_S	216_Q	1.102	1.00
131_L	413_T	1.102	1.00
227_W	244_F	1.100	1.00
82_V	85_Q	1.099	1.00
119_E	373_V	1.098	1.00
216_Q	437_Y	1.094	1.00
205_H	429_A	1.093	1.00
237_N	255_L	1.089	1.00
277_L	289_Q	1.087	1.00
145_V	152_V	1.083	1.00
300_R	329_F	1.082	1.00
195_E	199_Q	1.081	1.00
84_Q	356_D	1.077	1.00
290_A	338_H	1.069	1.00
138_I	399_F	1.063	1.00
81_Q	85_Q	1.060	1.00
389_A	413_T	1.060	1.00
201_Q	429_A	1.059	1.00
393_S	405_T	1.058	1.00
81_Q	84_Q	1.057	1.00
355_S	397_L	1.056	1.00
285_E	289_Q	1.054	1.00
307_V	328_L	1.053	1.00
277_L	299_D	1.051	1.00
288_K	291_V	1.047	1.00
274_K	366_S	1.047	1.00
421_C	444_V	1.041	1.00
102_F	105_G	1.030	1.00
294_A	331_V	1.028	1.00
143_L	152_V	1.021	1.00
271_R	343_T	1.006	0.99
222_Y	419_I	1.005	0.99
254_S	394_I	1.003	0.99
54_I	140_D	1.003	0.99
200_V	209_C	1.000	0.99
212_V	378_I	0.999	0.99
291_V	294_A	0.999	0.99
88_D	353_H	0.998	0.99
222_Y	229_A	0.994	0.99
209_C	378_I	0.994	0.99
201_Q	205_H	0.993	0.99
230_F	234_N	0.991	0.99
380_D	386_R	0.987	0.99
160_V	167_L	0.985	0.99
200_V	427_I	0.985	0.99
260_F	361_A	0.984	0.99
159_D	163_R	0.984	0.99
239_A	242_S	0.984	0.99
28_L	52_E	0.984	0.99
142_A	155_L	0.982	0.99
274_K	303_N	0.981	0.99
165_A	169_S	0.977	0.99
164_R	167_L	0.975	0.99
421_C	448_L	0.972	0.99
135_A	247_L	0.970	0.99
116_R	380_D	0.969	0.99
188_M	384_P	0.964	0.99
296_S	435_A	0.964	0.99
78_D	117_R	0.963	0.99
243_A	406_S	0.958	0.99
237_N	336_A	0.957	0.99
141_W	156_S	0.956	0.99
319_V	322_S	0.954	0.99
306_I	366_S	0.952	0.99
260_F	270_T	0.952	0.99
268_I	357_L	0.951	0.99
263_C	354_A	0.950	0.99
21_Y	25_L	0.947	0.99
68_E	71_K	0.946	0.99
84_Q	359_R	0.946	0.99
437_Y	440_T	0.942	0.99
213_N	368_T	0.940	0.99
277_L	442_D	0.938	0.99
53_P	139_Y	0.934	0.99
314_I	361_A	0.933	0.99
118_F	362_F	0.929	0.99
274_K	306_I	0.927	0.99
185_Q	219_H	0.926	0.99
294_A	300_R	0.924	0.99
278_P	442_D	0.922	0.99
110_F	397_L	0.918	0.99
110_F	358_L	0.914	0.99
114_L	134_M	0.913	0.99
259_R	269_Q	0.911	0.99
251_A	414_A	0.910	0.99
252_I	394_I	0.909	0.99
109_L	389_A	0.905	0.99
412_L	421_C	0.901	0.99
445_N	449_K	0.901	0.99
67_S	70_E	0.897	0.99
249_Q	415_I	0.897	0.99
213_N	391_C	0.896	0.99
266_S	319_V	0.895	0.99
129_I	420_F	0.894	0.99
200_V	382_L	0.889	0.99
239_A	336_A	0.888	0.99
303_N	306_I	0.888	0.99
60_F	63_E	0.884	0.99
215_A	440_T	0.883	0.99
54_I	138_I	0.882	0.99
58_T	135_A	0.867	0.98
265_N	402_N	0.862	0.98
278_P	289_Q	0.860	0.98
50_V	107_L	0.858	0.98
121_L	377_E	0.858	0.98
242_S	255_L	0.856	0.98
56_T	135_A	0.855	0.98
374_R	378_I	0.855	0.98
353_H	356_D	0.854	0.98
59_T	64_T	0.853	0.98
17_A	20_F	0.853	0.98
115_G	376_M	0.852	0.98
213_N	367_I	0.852	0.98
110_F	134_M	0.849	0.98
164_R	168_E	0.848	0.98
55_C	86_V	0.847	0.98
364_G	406_S	0.847	0.98
184_W	448_L	0.844	0.98
182_S	221_T	0.843	0.98
160_V	164_R	0.840	0.98
32_M	139_Y	0.838	0.98
83_L	136_V	0.837	0.98
122_P	377_E	0.836	0.98
159_D	162_A	0.836	0.98
218_F	448_L	0.834	0.98
367_I	409_I	0.830	0.98
20_F	24_R	0.830	0.98
114_L	117_R	0.830	0.98
128_D	385_Q	0.829	0.98
327_E	343_T	0.828	0.98
110_F	136_V	0.823	0.98
197_F	201_Q	0.822	0.98
191_E	194_G	0.822	0.98
196_K	384_P	0.822	0.98
204_L	429_A	0.820	0.98
299_D	435_A	0.819	0.98
212_V	375_A	0.817	0.98
163_R	167_L	0.817	0.98
218_F	441_F	0.816	0.98
80_L	114_L	0.816	0.98
165_A	168_E	0.815	0.98
52_E	141_W	0.803	0.97
48_I	142_A	0.794	0.97
198_R	205_H	0.793	0.97
194_G	432_Q	0.790	0.97
217_R	422_S	0.789	0.97
194_G	197_F	0.789	0.97
335_P	446_R	0.787	0.97
113_D	116_R	0.783	0.97
230_F	253_L	0.783	0.97
86_V	89_R	0.783	0.97
96_H	100_L	0.782	0.97
334_F	341_V	0.779	0.97
315_G	320_A	0.779	0.97
22_F	25_L	0.774	0.97
260_F	274_K	0.772	0.97
55_C	66_V	0.771	0.97
270_T	361_A	0.771	0.97
123_E	380_D	0.771	0.97
310_M	364_G	0.770	0.97
324_K	347_Q	0.769	0.97
196_K	214_L	0.768	0.97
300_R	328_L	0.765	0.97
125_A	380_D	0.765	0.97
303_N	391_C	0.763	0.97
397_L	403_M	0.762	0.96
218_F	423_A	0.761	0.96
278_P	435_A	0.756	0.96
263_C	266_S	0.752	0.96
330_V	343_T	0.752	0.96
26_S	246_R	0.748	0.96
74_T	77_D	0.747	0.96
35_H	230_F	0.747	0.96
196_K	200_V	0.745	0.96
131_L	250_G	0.744	0.96
262_L	269_Q	0.744	0.96
186_S	440_T	0.742	0.96
292_K	295_N	0.742	0.96
245_L	394_I	0.741	0.96
57_L	82_V	0.740	0.96
45_R	148_Q	0.737	0.96
116_R	123_E	0.735	0.96
18_A	21_Y	0.735	0.96
308_D	311_R	0.735	0.96
278_P	281_P	0.734	0.96
97_N	100_L	0.734	0.96
46_F	144_I	0.731	0.96
163_R	170_Q	0.730	0.96
259_R	271_R	0.729	0.95
303_N	366_S	0.727	0.95
107_L	245_L	0.724	0.95
309_L	365_G	0.722	0.95
303_N	310_M	0.719	0.95
284_Q	287_S	0.719	0.95
111_G	133_D	0.718	0.95
250_G	415_I	0.717	0.95
22_F	227_W	0.716	0.95
115_G	118_F	0.714	0.95
367_I	407_I	0.713	0.95
105_G	399_F	0.709	0.95
425_G	435_A	0.708	0.95
160_V	166_W	0.705	0.95
364_G	391_C	0.705	0.95
312_N	316_R	0.704	0.95
378_I	381_E	0.704	0.95
63_E	74_T	0.702	0.94
282_D	288_K	0.700	0.94
69_S	72_R	0.699	0.94
268_I	346_A	0.699	0.94
260_F	303_N	0.699	0.94
301_A	430_D	0.699	0.94
188_M	216_Q	0.699	0.94
59_T	134_M	0.699	0.94
116_R	122_P	0.699	0.94
354_A	403_M	0.698	0.94
130_V	415_I	0.697	0.94
28_L	246_R	0.696	0.94
60_F	133_D	0.696	0.94
261_I	361_A	0.694	0.94
135_A	250_G	0.693	0.94
60_F	65_V	0.692	0.94
37_G	40_D	0.690	0.94
200_V	379_I	0.688	0.94
58_T	67_S	0.687	0.94
278_P	438_Q	0.687	0.94
293_L	331_V	0.687	0.94
263_C	403_M	0.687	0.94
336_A	446_R	0.686	0.94
278_P	285_E	0.685	0.94
290_A	294_A	0.685	0.94
358_L	403_M	0.685	0.94
414_A	417_G	0.685	0.94
77_D	81_Q	0.685	0.94
187_N	219_H	0.684	0.94
217_R	385_Q	0.681	0.94
115_G	380_D	0.679	0.93
54_I	106_A	0.678	0.93
116_R	133_D	0.677	0.93
51_A	141_W	0.677	0.93
188_M	192_Q	0.677	0.93
295_N	300_R	0.676	0.93
110_F	405_T	0.675	0.93
325_V	328_L	0.675	0.93
20_F	23_S	0.674	0.93
118_F	359_R	0.674	0.93
252_I	411_T	0.674	0.93
373_V	377_E	0.672	0.93
21_Y	143_L	0.671	0.93
356_D	360_A	0.671	0.93
260_F	310_M	0.670	0.93
303_N	338_H	0.668	0.93
260_F	306_I	0.668	0.93
327_E	332_E	0.668	0.93
215_A	424_G	0.667	0.93
117_R	133_D	0.665	0.93
373_V	376_M	0.658	0.92
203_Y	377_E	0.657	0.92
300_R	304_L	0.657	0.92
311_R	370_A	0.656	0.92
261_I	403_M	0.652	0.92
123_E	386_R	0.651	0.92
162_A	166_W	0.651	0.92
237_N	446_R	0.650	0.92
110_F	395_G	0.650	0.92
292_K	296_S	0.649	0.92
229_A	419_I	0.648	0.92
159_D	167_L	0.647	0.92
59_T	79_P	0.642	0.91
65_V	72_R	0.642	0.91
391_C	406_S	0.642	0.91
48_I	107_L	0.641	0.91
26_S	225_D	0.639	0.91
266_S	348_L	0.638	0.91
119_E	316_R	0.638	0.91
28_L	51_A	0.638	0.91
364_G	367_I	0.637	0.91
18_A	22_F	0.637	0.91
329_F	340_L	0.636	0.91
385_Q	422_S	0.636	0.91
102_F	404_D	0.634	0.91
187_N	216_Q	0.632	0.91
270_T	314_I	0.632	0.91
268_I	348_L	0.628	0.91
213_N	406_S	0.628	0.91
331_V	338_H	0.625	0.90
127_Q	217_R	0.625	0.90
236_A	449_K	0.624	0.90
347_Q	350_E	0.624	0.90
129_I	386_R	0.622	0.90
158_N	167_L	0.621	0.90
88_D	91_D	0.621	0.90
132_P	250_G	0.620	0.90
310_M	391_C	0.620	0.90
247_L	250_G	0.619	0.90
441_F	445_N	0.617	0.90
85_Q	88_D	0.617	0.90
308_D	313_D	0.615	0.90
143_L	154_L	0.613	0.89
22_F	49_V	0.612	0.89
270_T	344_I	0.611	0.89
303_N	307_V	0.611	0.89
141_W	154_L	0.608	0.89
201_Q	433_E	0.607	0.89
390_W	425_G	0.606	0.89
227_W	231_L	0.603	0.89
157_H	399_F	0.601	0.89
125_A	128_D	0.599	0.88
211_Q	428_V	0.599	0.88
243_A	411_T	0.599	0.88
63_E	76_T	0.597	0.88
254_S	408_T	0.597	0.88
17_A	24_R	0.596	0.88
18_A	25_L	0.596	0.88
112_Y	368_T	0.596	0.88
39_A	44_S	0.595	0.88
93_R	97_N	0.595	0.88
240_P	334_F	0.594	0.88
271_R	330_V	0.593	0.88
64_T	82_V	0.593	0.88
35_H	242_S	0.592	0.88
303_N	342_S	0.591	0.88
444_V	448_L	0.591	0.88
187_N	217_R	0.590	0.88
301_A	311_R	0.590	0.88
210_Y	312_N	0.590	0.88
210_Y	368_T	0.589	0.88
223_S	417_G	0.589	0.88
19_E	231_L	0.588	0.87
159_D	166_W	0.588	0.87
277_L	338_H	0.587	0.87
252_I	408_T	0.586	0.87
213_N	375_A	0.584	0.87
213_N	364_G	0.584	0.87
17_A	231_L	0.584	0.87
297_A	300_R	0.584	0.87
68_E	73_T	0.579	0.87
194_G	437_Y	0.577	0.86
139_Y	142_A	0.576	0.86
197_F	425_G	0.575	0.86
127_Q	415_I	0.575	0.86
213_N	254_S	0.573	0.86
413_T	420_F	0.573	0.86
77_D	85_Q	0.572	0.86
316_R	373_V	0.572	0.86
255_L	447_I	0.572	0.86
364_G	375_A	0.570	0.86
22_F	244_F	0.570	0.86
186_S	218_F	0.568	0.86
254_S	364_G	0.568	0.86
203_Y	209_C	0.566	0.85
233_L	255_L	0.565	0.85
243_A	364_G	0.565	0.85
163_R	168_E	0.564	0.85
238_R	255_L	0.563	0.85
65_V	68_E	0.561	0.85
260_F	366_S	0.561	0.85
238_R	335_P	0.561	0.85
279_R	333_P	0.559	0.85
299_D	366_S	0.559	0.85
267_E	326_P	0.558	0.85
131_L	389_A	0.558	0.85
213_N	243_A	0.557	0.84
415_I	418_Q	0.557	0.84
104_G	142_A	0.556	0.84
129_I	388_N	0.553	0.84
210_Y	311_R	0.553	0.84
442_D	445_N	0.553	0.84
211_Q	306_I	0.553	0.84
29_P	248_E	0.552	0.84
31_A	246_R	0.552	0.84
27_H	246_R	0.551	0.84
224_G	229_A	0.550	0.84
280_L	286_D	0.550	0.84
273_I	409_I	0.549	0.84
254_S	391_C	0.549	0.84
120_S	377_E	0.549	0.84
84_Q	355_S	0.548	0.84
367_I	408_T	0.547	0.83
75_T	79_P	0.547	0.83
305_M	308_D	0.547	0.83
103_Q	398_S	0.546	0.83
90_A	399_F	0.546	0.83
67_S	72_R	0.546	0.83
161_N	165_A	0.545	0.83
200_V	213_N	0.545	0.83
366_S	425_G	0.545	0.83
336_A	449_K	0.544	0.83
85_Q	89_R	0.543	0.83
133_D	386_R	0.543	0.83
261_I	357_L	0.542	0.83
305_M	311_R	0.542	0.83
271_R	334_F	0.542	0.83
136_V	395_G	0.541	0.83
384_P	422_S	0.540	0.83
308_D	312_N	0.539	0.83
274_K	428_V	0.539	0.83
103_Q	400_C	0.539	0.83
296_S	367_I	0.538	0.82
274_K	425_G	0.538	0.82
228_Q	231_L	0.538	0.82
100_L	153_S	0.536	0.82
305_M	313_D	0.536	0.82
186_S	423_A	0.535	0.82
213_N	310_M	0.534	0.82
201_Q	428_V	0.534	0.82
196_K	382_L	0.533	0.82
377_E	381_E	0.533	0.82
83_L	90_A	0.532	0.82
125_A	384_P	0.532	0.82
197_F	214_L	0.531	0.82
214_L	382_L	0.531	0.82
441_F	448_L	0.531	0.82
294_A	297_A	0.530	0.81
367_I	447_I	0.530	0.81
303_N	329_F	0.529	0.81
318_A	323_V	0.529	0.81
395_G	403_M	0.528	0.81
286_D	338_H	0.528	0.81
164_R	170_Q	0.526	0.81
284_Q	350_E	0.526	0.81
310_M	366_S	0.524	0.81
236_A	336_A	0.524	0.81
19_E	227_W	0.524	0.81
317_V	357_L	0.523	0.81
86_V	90_A	0.523	0.81
195_E	202_E	0.522	0.80
259_R	364_G	0.522	0.80
55_C	68_E	0.522	0.80
308_D	370_A	0.521	0.80
280_L	283_P	0.520	0.80
339_H	367_I	0.519	0.80
59_T	117_R	0.519	0.80
57_L	64_T	0.518	0.80
66_V	75_T	0.518	0.80
188_M	214_L	0.517	0.80
64_T	74_T	0.517	0.80
184_W	451_L	0.516	0.80
226_E	253_L	0.516	0.80
162_A	165_A	0.515	0.80
193_Y	440_T	0.515	0.80
299_D	428_V	0.515	0.80
125_A	386_R	0.514	0.79
178_F	224_G	0.513	0.79
54_I	59_T	0.512	0.79
301_A	305_M	0.512	0.79
115_G	366_S	0.511	0.79
54_I	399_F	0.510	0.79
203_Y	382_L	0.510	0.79
119_E	376_M	0.510	0.79
306_I	310_M	0.509	0.79
259_R	396_Y	0.508	0.79
375_A	426_G	0.508	0.79
108_G	136_V	0.507	0.79
218_F	444_V	0.507	0.79
61_G	65_V	0.506	0.78
357_L	361_A	0.505	0.78
56_T	137_G	0.505	0.78
253_L	412_L	0.505	0.78
146_D	151_T	0.505	0.78
17_A	25_L	0.505	0.78
226_E	246_R	0.504	0.78
49_V	143_L	0.503	0.78
203_Y	206_S	0.503	0.78
200_V	378_I	0.503	0.78
25_L	49_V	0.502	0.78
63_E	67_S	0.502	0.78
305_M	312_N	0.502	0.78
362_F	391_C	0.501	0.78
341_V	408_T	0.501	0.78
313_D	370_A	0.500	0.78
239_A	335_P	0.500	0.78

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1k0eA	1	0.9691	100	0.111	Contact Map
1i1qA	2	0.9823	100	0.144	Contact Map
4grhA	1	0.936	100	0.149	Contact Map
1qdlA	1	0.9095	100	0.152	Contact Map
3logA	1	0.9448	100	0.198	Contact Map
3h9mA	1	0.8653	100	0.208	Contact Map
2fn0A	2	0.894	100	0.25	Contact Map
3gseA	1	0.8587	100	0.303	Contact Map
3bzmA	1	0.883	100	0.331	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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