ILVA - ECOLI - GREMLIN Contacts

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ILVA - L-threonine dehydratase biosynthetic IlvA

UniProt:	P04968	Sequences: MADSQPLSGAPEGAEYLRAVLRAPVYEAAQVTPLQKMEKLSSRLDNVILVKREDRQPVHSFKLRGAYAMMAGLTEEQKAHGVITASAGNHAQGVAFSSARLGVKALIVMPTATADIKVDAVRGFGGEVLLHGANFDEAKAKAIELSQQQGFTWVPPFDHPMVIAGQGTLALELLQQDAHLDRVFVPVGGGGLAAGVAVLIKQLMPQIKVIAVEAEDSACLKAALDAGHPVDLPRVGLFAEGVAVKRIGDETFRLCQEYLDDIITVDSDAICAAMKDLFEDVRAVAEPSGALALAGMKKYIALHNIRGERLAHILSGANVNFHGLRYVSERCELGEQREALLAVTIPEEKGSFLKFCQLLGGRSVTEFNYRFADAKNACIFVGVRLSRGLEERKEILQMLNDGGYSVVDLSDDEMAKLHVRYMVGGRPSHPLQERLYSFEFPESPGALLRFLNTLGTYWNISLFHYRSHGTDYGRVLAAFELGDHEPDFETRLNELGYDCHDETNNPAFRFFLAG	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10493
Length:	514 (399)
Sequences:	1362 (719)
Seq/√Len:	36.0

ECOLI - ILVA
BACSU - ILVA
HALSA - Q9HNH6
SULSO - Q980P1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
183_V	200_I	6.577	1.00
141_K	144_E	5.347	1.00
193_A	259_L	5.184	1.00
74_T	77_Q	4.180	1.00
250_E	253_R	4.102	1.00
69_M	159_H	4.029	1.00
221_K	225_D	3.820	1.00
173_L	311_A	3.572	1.00
106_L	127_E	3.294	1.00
98_S	105_A	3.223	1.00
214_A	242_V	3.172	1.00
218_A	222_A	2.806	1.00
144_E	148_Q	2.781	1.00
47_V	309_R	2.754	1.00
186_P	315_S	2.743	1.00
104_K	127_E	2.727	1.00
218_A	264_T	2.723	1.00
341_L	396_L	2.682	1.00
187_V	220_L	2.671	1.00
170_A	196_V	2.661	1.00
204_M	207_I	2.657	1.00
220_L	247_I	2.637	1.00
72_G	161_M	2.609	1.00
215_E	266_D	2.608	1.00
185_V	196_V	2.546	1.00
48_I	300_I	2.489	1.00
219_C	223_A	2.484	1.00
180_L	311_A	2.474	1.00
231_D	246_R	2.431	1.00
193_A	255_C	2.361	1.00
269_A	298_K	2.335	0.99
197_A	258_Y	2.332	0.99
75_E	78_K	2.315	0.99
220_L	262_I	2.295	0.99
196_V	313_I	2.174	0.99
242_V	288_S	2.164	0.99
141_K	145_L	2.157	0.99
285_A	314_L	2.146	0.99
254_L	258_Y	2.142	0.99
180_L	207_I	2.104	0.99
49_L	309_R	2.101	0.99
266_D	269_A	2.098	0.99
31_V	175_Q	2.012	0.98
104_K	151_F	2.011	0.98
143_I	146_S	1.999	0.98
33_P	55_R	1.995	0.98
75_E	79_A	1.986	0.98
48_I	296_M	1.982	0.98
187_V	262_I	1.977	0.98
358_L	402_G	1.963	0.98
293_L	296_M	1.958	0.98
99_A	105_A	1.937	0.98
224_L	262_I	1.919	0.98
158_D	249_D	1.893	0.98
221_K	262_I	1.869	0.97
274_M	288_S	1.861	0.97
50_V	312_H	1.856	0.97
216_D	236_G	1.852	0.97
221_K	264_T	1.841	0.97
19_A	161_M	1.826	0.97
397_Q	401_D	1.792	0.97
181_D	308_E	1.787	0.97
173_L	180_L	1.761	0.96
201_K	260_D	1.759	0.96
239_A	270_I	1.750	0.96
210_I	261_D	1.731	0.96
229_P	249_D	1.725	0.96
242_V	291_L	1.706	0.96
77_Q	152_T	1.701	0.96
36_K	47_V	1.699	0.96
183_V	196_V	1.686	0.95
77_Q	80_H	1.673	0.95
106_L	151_F	1.669	0.95
223_A	285_A	1.641	0.95
135_F	139_K	1.633	0.94
108_V	145_L	1.629	0.94
274_M	319_V	1.626	0.94
255_C	259_L	1.608	0.94
139_K	143_I	1.601	0.94
170_A	173_L	1.597	0.94
170_A	200_I	1.582	0.93
409_L	412_D	1.579	0.93
226_A	230_V	1.575	0.93
17_L	202_Q	1.575	0.93
246_R	249_D	1.568	0.93
76_E	80_H	1.567	0.93
218_A	221_K	1.565	0.93
348_E	354_K	1.564	0.93
78_K	103_V	1.561	0.93
215_E	264_T	1.555	0.93
24_P	68_A	1.547	0.93
46_N	308_E	1.535	0.92
31_V	176_Q	1.523	0.92
171_L	199_L	1.518	0.92
186_P	242_V	1.496	0.91
145_L	149_Q	1.493	0.91
229_P	246_R	1.469	0.91
277_L	285_A	1.466	0.91
99_A	126_G	1.465	0.90
208_K	261_D	1.452	0.90
214_A	217_S	1.440	0.90
129_L	141_K	1.402	0.88
219_C	247_I	1.398	0.88
83_I	151_F	1.394	0.88
145_L	151_F	1.389	0.88
216_D	267_S	1.382	0.88
99_A	124_F	1.370	0.87
84_T	155_P	1.366	0.87
228_H	249_D	1.352	0.87
174_L	200_I	1.347	0.86
44_L	300_I	1.334	0.86
296_M	300_I	1.325	0.85
74_T	78_K	1.325	0.85
196_V	200_I	1.322	0.85
157_F	246_R	1.315	0.85
185_V	209_V	1.307	0.85
134_N	137_E	1.288	0.84
181_D	309_R	1.287	0.84
85_A	135_F	1.285	0.84
155_P	159_H	1.281	0.83
222_A	230_V	1.265	0.83
183_V	209_V	1.261	0.82
393_K	397_Q	1.253	0.82
274_M	327_V	1.253	0.82
261_D	302_L	1.253	0.82
333_L	410_S	1.245	0.82
193_A	209_V	1.228	0.81
359_L	381_V	1.216	0.80
36_K	49_L	1.214	0.80
220_L	255_C	1.213	0.80
223_A	247_I	1.212	0.80
44_L	48_I	1.211	0.80
70_M	94_V	1.204	0.79
227_G	256_Q	1.199	0.79
25_V	28_A	1.197	0.79
104_K	149_Q	1.196	0.79
181_D	307_G	1.191	0.79
70_M	101_L	1.187	0.78
385_L	388_G	1.172	0.77
70_M	103_V	1.162	0.77
169_L	196_V	1.148	0.76
239_A	288_S	1.148	0.76
131_H	141_K	1.147	0.76
160_P	250_E	1.144	0.76
69_M	155_P	1.141	0.76
113_T	156_P	1.141	0.76
113_T	116_I	1.134	0.75
34_L	177_D	1.131	0.75
142_A	153_W	1.122	0.74
332_E	337_R	1.118	0.74
94_V	103_V	1.116	0.74
119_D	122_R	1.114	0.74
300_I	310_L	1.110	0.73
193_A	211_A	1.110	0.73
135_F	155_P	1.106	0.73
48_I	305_I	1.106	0.73
40_L	50_V	1.097	0.73
400_N	405_S	1.092	0.72
182_R	208_K	1.090	0.72
139_K	153_W	1.090	0.72
46_N	305_I	1.085	0.72
279_E	337_R	1.082	0.72
276_D	297_K	1.080	0.71
239_A	242_V	1.070	0.71
222_A	226_A	1.070	0.71
219_C	222_A	1.068	0.71
349_K	412_D	1.056	0.70
134_N	245_K	1.050	0.69
42_S	123_G	1.050	0.69
209_V	254_L	1.029	0.68
112_A	364_V	1.020	0.67
68_A	72_G	1.019	0.67
25_V	60_S	1.016	0.67
84_T	153_W	1.016	0.67
108_V	138_A	1.016	0.67
184_F	299_Y	1.015	0.67
139_K	155_P	1.009	0.66
47_V	307_G	1.003	0.66
106_L	149_Q	0.994	0.65
319_V	327_V	0.994	0.65
115_D	119_D	0.985	0.64
171_L	175_Q	0.982	0.64
83_I	152_T	0.980	0.64
240_E	293_L	0.978	0.64
240_E	312_H	0.977	0.64
292_A	312_H	0.975	0.63
396_L	406_V	0.974	0.63
182_R	308_E	0.973	0.63
412_D	415_A	0.969	0.63
363_S	384_R	0.966	0.63
84_T	259_L	0.962	0.62
279_E	314_L	0.960	0.62
222_A	225_D	0.948	0.61
222_A	264_T	0.946	0.61
351_S	354_K	0.946	0.61
198_V	254_L	0.944	0.61
211_A	220_L	0.939	0.60
305_I	308_E	0.938	0.60
40_L	293_L	0.930	0.60
224_L	255_C	0.929	0.60
105_A	162_V	0.926	0.59
173_L	183_V	0.922	0.59
209_V	259_L	0.922	0.59
219_C	285_A	0.921	0.59
157_F	414_M	0.919	0.59
109_M	130_L	0.918	0.59
253_R	256_Q	0.917	0.59
278_F	284_V	0.917	0.59
111_T	133_A	0.915	0.58
341_L	399_L	0.909	0.58
273_A	297_K	0.909	0.58
136_D	217_S	0.908	0.58
249_D	361_G	0.907	0.58
180_L	309_R	0.902	0.57
295_G	315_S	0.901	0.57
362_R	391_E	0.900	0.57
344_T	405_S	0.899	0.57
21_L	31_V	0.898	0.57
174_L	204_M	0.896	0.57
34_L	311_A	0.892	0.56
186_P	262_I	0.888	0.56
355_F	381_V	0.876	0.55
213_E	217_S	0.875	0.55
49_L	177_D	0.873	0.55
349_K	371_F	0.871	0.55
73_L	77_Q	0.871	0.55
179_H	206_Q	0.868	0.54
17_L	21_L	0.867	0.54
133_A	214_A	0.866	0.54
32_T	97_S	0.865	0.54
105_A	126_G	0.864	0.54
116_I	371_F	0.855	0.53
174_L	183_V	0.852	0.53
25_V	67_Y	0.850	0.53
393_K	400_N	0.850	0.53
28_A	67_Y	0.849	0.53
219_C	264_T	0.849	0.53
215_E	218_A	0.844	0.52
103_V	319_V	0.843	0.52
25_V	29_A	0.843	0.52
78_K	104_K	0.842	0.52
125_G	315_S	0.841	0.52
261_D	303_H	0.840	0.52
113_T	240_E	0.830	0.51
385_L	391_E	0.830	0.51
214_A	270_I	0.829	0.51
40_L	44_L	0.829	0.51
198_V	258_Y	0.828	0.51
157_F	314_L	0.827	0.51
127_E	149_Q	0.824	0.51
223_A	246_R	0.821	0.50
396_L	400_N	0.820	0.50
83_I	146_S	0.819	0.50
183_V	311_A	0.819	0.50
118_V	136_D	0.818	0.50
187_V	193_A	0.815	0.50
214_A	239_A	0.815	0.50
187_V	255_C	0.814	0.50
211_A	259_L	0.813	0.50
46_N	181_D	0.812	0.50
213_E	223_A	0.809	0.49
155_P	251_T	0.808	0.49
336_Q	411_D	0.807	0.49
362_R	398_M	0.807	0.49
61_F	120_A	0.807	0.49
352_F	367_F	0.804	0.49
251_T	254_L	0.801	0.49
261_D	401_D	0.800	0.48
400_N	406_V	0.798	0.48
146_S	153_W	0.797	0.48
185_V	292_A	0.796	0.48
277_L	314_L	0.795	0.48
126_G	143_I	0.794	0.48
255_C	262_I	0.793	0.48
344_T	376_N	0.793	0.48
296_M	312_H	0.792	0.48
208_K	308_E	0.792	0.48
48_I	301_A	0.792	0.48
345_I	351_S	0.789	0.48
120_A	404_Y	0.789	0.48
29_A	35_Q	0.787	0.47
136_D	213_E	0.787	0.47
157_F	251_T	0.785	0.47
163_I	254_L	0.781	0.47
25_V	71_A	0.777	0.46
274_M	283_A	0.775	0.46
186_P	288_S	0.773	0.46
108_V	141_K	0.771	0.46
186_P	197_A	0.770	0.46
354_K	402_G	0.769	0.46
46_N	300_I	0.769	0.46
217_S	414_M	0.769	0.46
349_K	399_L	0.768	0.46
345_I	352_F	0.767	0.46
84_T	126_G	0.766	0.46
324_L	341_L	0.763	0.45
116_I	315_S	0.762	0.45
230_V	252_F	0.761	0.45
213_E	221_K	0.760	0.45
216_D	235_V	0.759	0.45
126_G	349_K	0.758	0.45
325_R	328_S	0.757	0.45
148_Q	395_I	0.757	0.45
50_V	240_E	0.755	0.45
296_M	310_L	0.753	0.44
113_T	170_A	0.751	0.44
181_D	207_I	0.749	0.44
179_H	204_M	0.749	0.44
362_R	395_I	0.742	0.43
211_A	262_I	0.739	0.43
348_E	375_K	0.739	0.43
77_Q	226_A	0.735	0.43
129_L	145_L	0.732	0.43
187_V	211_A	0.732	0.43
42_S	208_K	0.731	0.43
267_S	384_R	0.728	0.42
29_A	56_Q	0.725	0.42
20_V	23_A	0.725	0.42
43_R	297_K	0.723	0.42
209_V	306_R	0.721	0.42
45_D	150_G	0.720	0.42
173_L	200_I	0.718	0.41
45_D	306_R	0.718	0.41
20_V	199_L	0.718	0.41
46_N	304_N	0.717	0.41
322_H	328_S	0.717	0.41
389_L	393_K	0.716	0.41
136_D	157_F	0.714	0.41
23_A	96_F	0.713	0.41
38_E	42_S	0.713	0.41
234_R	242_V	0.713	0.41
32_T	327_V	0.713	0.41
220_L	224_L	0.712	0.41
141_K	209_V	0.711	0.41
202_Q	258_Y	0.705	0.40
285_A	319_V	0.704	0.40
332_E	384_R	0.702	0.40
397_Q	400_N	0.700	0.40
284_V	319_V	0.699	0.40
252_F	256_Q	0.697	0.40
18_R	202_Q	0.696	0.40
170_A	405_S	0.695	0.40
277_L	293_L	0.693	0.39
238_F	267_S	0.692	0.39
213_E	242_V	0.691	0.39
143_I	147_Q	0.690	0.39
45_D	76_E	0.690	0.39
348_E	364_V	0.688	0.39
42_S	45_D	0.688	0.39
256_Q	348_E	0.688	0.39
218_A	223_A	0.688	0.39
21_L	175_Q	0.686	0.39
179_H	309_R	0.685	0.39
33_P	324_L	0.684	0.39
84_T	107_I	0.682	0.38
126_G	385_L	0.682	0.38
351_S	404_Y	0.679	0.38
45_D	100_R	0.679	0.38
96_F	100_R	0.678	0.38
63_L	97_S	0.676	0.38
355_F	379_I	0.676	0.38
170_A	298_K	0.673	0.38
126_G	146_S	0.673	0.38
356_C	404_Y	0.673	0.38
180_L	194_A	0.673	0.38
178_A	204_M	0.672	0.38
154_V	307_G	0.670	0.37
73_L	81_G	0.668	0.37
76_E	228_H	0.668	0.37
20_V	167_G	0.668	0.37
76_E	257_E	0.667	0.37
34_L	173_L	0.666	0.37
40_L	101_L	0.666	0.37
63_L	224_L	0.666	0.37
389_L	397_Q	0.665	0.37
209_V	385_L	0.665	0.37
217_S	232_L	0.662	0.37
130_L	138_A	0.662	0.37
19_A	139_K	0.661	0.37
146_S	337_R	0.661	0.37
345_I	367_F	0.659	0.37
256_Q	401_D	0.658	0.36
358_L	398_M	0.658	0.36
354_K	397_Q	0.658	0.36
178_A	206_Q	0.656	0.36
336_Q	389_L	0.656	0.36
253_R	257_E	0.655	0.36
147_Q	228_H	0.654	0.36
136_D	240_E	0.654	0.36
333_L	351_S	0.653	0.36
332_E	382_G	0.652	0.36
122_R	401_D	0.651	0.36
169_L	192_L	0.650	0.36
210_I	263_I	0.646	0.36
275_K	321_F	0.645	0.35
32_T	383_V	0.642	0.35
368_N	380_F	0.640	0.35
209_V	401_D	0.638	0.35
336_Q	392_R	0.636	0.35
147_Q	306_R	0.634	0.35
142_A	154_V	0.634	0.35
328_S	340_L	0.634	0.35
324_L	364_V	0.634	0.35
157_F	215_E	0.632	0.34
392_R	406_V	0.631	0.34
180_L	204_M	0.630	0.34
170_A	209_V	0.627	0.34
175_Q	319_V	0.627	0.34
116_I	284_V	0.626	0.34
198_V	203_L	0.625	0.34
293_L	314_L	0.624	0.34
216_D	271_C	0.623	0.34
80_H	150_G	0.622	0.34
140_A	211_A	0.621	0.34
353_L	357_Q	0.620	0.33
131_H	397_Q	0.618	0.33
181_D	310_L	0.617	0.33
124_F	149_Q	0.616	0.33
70_M	216_D	0.616	0.33
358_L	395_I	0.615	0.33
47_V	390_E	0.614	0.33
22_R	175_Q	0.613	0.33
254_L	257_E	0.613	0.33
279_E	388_G	0.610	0.33
69_M	77_Q	0.608	0.33
379_I	384_R	0.606	0.32
213_E	239_A	0.606	0.32
186_P	291_L	0.606	0.32
29_A	120_A	0.603	0.32
310_L	314_L	0.603	0.32
111_T	349_K	0.602	0.32
112_A	240_E	0.600	0.32
101_L	194_A	0.600	0.32
131_H	136_D	0.599	0.32
70_M	314_L	0.599	0.32
259_L	293_L	0.598	0.32
217_S	235_V	0.598	0.32
394_E	401_D	0.597	0.32
157_F	265_V	0.595	0.32
25_V	61_F	0.594	0.31
217_S	242_V	0.592	0.31
131_H	138_A	0.591	0.31
71_A	402_G	0.591	0.31
208_K	375_K	0.591	0.31
43_R	276_D	0.590	0.31
255_C	379_I	0.590	0.31
213_E	295_G	0.588	0.31
18_R	293_L	0.588	0.31
59_H	267_S	0.587	0.31
169_L	210_I	0.587	0.31
368_N	382_G	0.586	0.31
202_Q	406_V	0.586	0.31
163_I	250_E	0.586	0.31
103_V	298_K	0.586	0.31
128_V	340_L	0.585	0.31
242_V	270_I	0.585	0.31
69_M	72_G	0.585	0.31
131_H	313_I	0.584	0.31
75_E	99_A	0.583	0.31
197_A	201_K	0.583	0.31
293_L	312_H	0.582	0.31
114_A	162_V	0.582	0.31
187_V	213_E	0.581	0.31
186_P	313_I	0.580	0.30
136_D	140_A	0.579	0.30
17_L	22_R	0.577	0.30
80_H	152_T	0.576	0.30
39_K	280_D	0.575	0.30
300_I	305_I	0.574	0.30
58_V	270_I	0.573	0.30
73_L	78_K	0.572	0.30
59_H	323_G	0.572	0.30
301_A	336_Q	0.570	0.30
59_H	182_R	0.570	0.30
196_V	398_M	0.570	0.30
150_G	222_A	0.570	0.30
76_E	79_A	0.569	0.30
160_P	164_A	0.568	0.30
18_R	177_D	0.564	0.29
213_E	224_L	0.564	0.29
78_K	101_L	0.564	0.29
44_L	390_E	0.564	0.29
67_Y	281_V	0.564	0.29
386_S	395_I	0.564	0.29
268_D	334_G	0.563	0.29
37_M	288_S	0.562	0.29
103_V	108_V	0.561	0.29
338_E	370_R	0.561	0.29
272_A	334_G	0.560	0.29
52_R	321_F	0.560	0.29
284_V	364_V	0.560	0.29
365_T	370_R	0.559	0.29
270_I	291_L	0.559	0.29
68_A	168_T	0.558	0.29
84_T	175_Q	0.557	0.29
158_D	229_P	0.555	0.29
255_C	258_Y	0.553	0.28
194_A	256_Q	0.552	0.28
197_A	257_E	0.552	0.28
151_F	307_G	0.552	0.28
225_D	264_T	0.551	0.28
399_L	404_Y	0.550	0.28
176_Q	395_I	0.550	0.28
148_Q	225_D	0.549	0.28
133_A	138_A	0.549	0.28
67_Y	377_A	0.548	0.28
183_V	207_I	0.548	0.28
83_I	141_K	0.548	0.28
399_L	414_M	0.547	0.28
113_T	130_L	0.545	0.28
271_C	287_P	0.544	0.28
333_L	413_E	0.544	0.28
24_P	159_H	0.543	0.28
106_L	111_T	0.542	0.28
322_H	331_C	0.542	0.28
19_A	228_H	0.541	0.28
139_K	146_S	0.541	0.28
35_Q	120_A	0.540	0.28
121_V	126_G	0.540	0.28
107_I	366_E	0.540	0.28
136_D	245_K	0.539	0.28
103_V	142_A	0.539	0.28
275_K	279_E	0.538	0.27
238_F	365_T	0.538	0.27
84_T	314_L	0.537	0.27
297_K	335_E	0.537	0.27
225_D	306_R	0.536	0.27
134_N	327_V	0.534	0.27
83_I	153_W	0.534	0.27
275_K	282_R	0.533	0.27
115_D	126_G	0.533	0.27
154_V	291_L	0.531	0.27
74_T	152_T	0.529	0.27
147_Q	348_E	0.529	0.27
108_V	131_H	0.528	0.27
158_D	248_G	0.528	0.27
115_D	135_F	0.528	0.27
271_C	330_R	0.527	0.27
335_E	367_F	0.527	0.27
268_D	275_K	0.526	0.27
148_Q	258_Y	0.526	0.27
287_P	367_F	0.525	0.27
249_D	311_A	0.523	0.26
126_G	142_A	0.523	0.26
128_V	199_L	0.522	0.26
390_E	393_K	0.522	0.26
263_I	291_L	0.521	0.26
354_K	357_Q	0.521	0.26
36_K	39_K	0.519	0.26
185_V	214_A	0.519	0.26
200_I	204_M	0.519	0.26
201_K	209_V	0.519	0.26
112_A	214_A	0.518	0.26
171_L	384_R	0.518	0.26
59_H	412_D	0.518	0.26
383_V	392_R	0.516	0.26
394_E	397_Q	0.516	0.26
211_A	247_I	0.516	0.26
157_F	364_V	0.515	0.26
299_Y	305_I	0.515	0.26
169_L	313_I	0.514	0.26
338_E	365_T	0.514	0.26
57_P	96_F	0.514	0.26
228_H	256_Q	0.513	0.26
50_V	285_A	0.513	0.26
106_L	129_L	0.513	0.26
137_E	146_S	0.512	0.26
232_L	235_V	0.512	0.26
22_R	296_M	0.512	0.26
113_T	169_L	0.512	0.26
347_E	371_F	0.511	0.26
214_A	414_M	0.510	0.26
109_M	191_G	0.510	0.26
74_T	390_E	0.509	0.25
83_I	319_V	0.509	0.25
56_Q	399_L	0.508	0.25
193_A	196_V	0.508	0.25
92_Q	166_Q	0.507	0.25
181_D	204_M	0.507	0.25
111_T	157_F	0.506	0.25
140_A	400_N	0.506	0.25
120_A	142_A	0.505	0.25
70_M	305_I	0.505	0.25
272_A	276_D	0.504	0.25
24_P	71_A	0.504	0.25
85_A	122_R	0.504	0.25
187_V	247_I	0.504	0.25
111_T	131_H	0.503	0.25
84_T	240_E	0.503	0.25
287_P	325_R	0.502	0.25
31_V	171_L	0.502	0.25
174_L	207_I	0.501	0.25
80_H	104_K	0.501	0.25
377_A	382_G	0.501	0.25
47_V	147_Q	0.500	0.25
329_E	365_T	0.500	0.25
135_F	219_C	0.500	0.25
113_T	366_E	0.500	0.25

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1tdjA	2	0.9611	100	0.255	Contact Map
3iauA	1	0.6498	100	0.648	Contact Map
2gn0A	2	0.6362	100	0.65	Contact Map
3ss7X	1	0.644	100	0.659	Contact Map
1v71A	2	0.6187	100	0.66	Contact Map
1ve5A	3	0.5895	100	0.673	Contact Map
3l6bA	2	0.6206	100	0.674	Contact Map
2rkbA	2	0.5992	100	0.674	Contact Map
4h27A	1	0.5973	100	0.68	Contact Map
4d9iA	2	0.6381	100	0.686	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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