SYE - ECOLI - GREMLIN Contacts

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SYE - Glutamate--tRNA ligase

UniProt:	P04805	Sequences: MKIKTRFAPSPTGYLHVGGARTALYSWLFARNHGGEFVLRIEDTDLERSTPEAIEAIMDGMNWLSLEWDEGPYYQTKRFDRYNAVIDQMLEEGTAYKCYCSKERLEALREEQMAKGEKPRYDGRCRHSHEHHADDEPCVVRFANPQEGSVVFDDQIRGPIEFSNQELDDLIIRRTDGSPTYNFCVVVDDWDMEITHVIRGEDHINNTPRQINILKALKAPVPVYAHVSMINGDDGKKLSKRHGAVSVMQYRDDGYLPEALLNYLVRLGWSHGDQEIFTREEMIKYFTLNAVSKSASAFNTDKLLWLNHHYINALPPEYVATHLQWHIEQENIDTRNGPQLADLVKLLGERCKTLKEMAQSCRYFYEDFAEFDADAAKKHLRPVARQPLEVVRDKLAAITDWTAENVHHAIQATADELEVGMGKVGMPLRVAVTGAGQSPALDVTVHAIGKTRSIERINKALDFIAERENQQ	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10407
Length:	471 (412)
Sequences:	6599 (3693)
Seq/√Len:	181.9

ECOLI - SYE GLUQ SYQ
BACSU - SYE
HALSA - SYE
SULSO - SYE

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
88_Q	92_E	5.004	1.00
153_D	159_P	4.671	1.00
87_D	91_E	4.619	1.00
51_P	55_E	4.141	1.00
99_Y	138_C	3.204	1.00
100_C	125_C	3.177	1.00
316_P	348_G	3.162	1.00
55_E	59_D	2.934	1.00
215_K	221_V	2.842	1.00
214_L	224_Y	2.724	1.00
121_Y	125_C	2.705	1.00
111_E	115_K	2.701	1.00
190_W	219_A	2.571	1.00
101_S	104_R	2.452	1.00
129_H	132_H	2.435	1.00
402_T	405_N	2.423	1.00
127_H	131_H	2.415	1.00
150_V	164_N	2.391	1.00
317_E	341_A	2.339	1.00
85_V	191_D	2.307	1.00
62_N	67_E	2.290	1.00
80_D	84_A	2.282	1.00
107_A	111_E	2.275	1.00
280_E	284_K	2.254	1.00
86_I	140_V	2.231	1.00
54_I	74_Y	2.208	1.00
151_V	161_E	2.204	1.00
87_D	130_E	2.194	1.00
157_R	201_E	2.187	1.00
151_V	159_P	2.181	1.00
255_Y	304_L	2.180	1.00
81_R	191_D	2.172	1.00
394_K	416_E	2.171	1.00
94_T	216_A	2.136	1.00
110_E	113_M	2.122	1.00
74_Y	77_K	2.098	1.00
62_N	68_W	2.060	1.00
29_F	33_H	2.057	1.00
149_S	161_E	2.011	1.00
383_V	386_Q	2.009	1.00
100_C	108_L	2.008	1.00
211_I	221_V	2.005	1.00
160_I	204_I	1.997	1.00
407_H	411_Q	1.995	1.00
308_H	312_N	1.989	1.00
390_V	417_L	1.976	1.00
134_D	137_P	1.970	1.00
4_K	194_I	1.963	1.00
81_R	85_V	1.920	1.00
155_Q	223_V	1.895	1.00
314_L	318_Y	1.888	1.00
149_S	163_S	1.888	1.00
82_Y	188_D	1.842	1.00
108_L	122_D	1.821	1.00
38_V	194_I	1.818	1.00
148_G	215_K	1.815	1.00
7_F	19_G	1.807	1.00
84_A	88_Q	1.787	1.00
4_K	36_E	1.773	1.00
39_L	58_M	1.770	1.00
15_L	19_G	1.768	1.00
315_P	318_Y	1.745	1.00
278_T	281_E	1.744	1.00
235_G	297_A	1.738	1.00
97_K	138_C	1.727	1.00
80_D	170_L	1.725	1.00
393_D	396_A	1.722	1.00
153_D	223_V	1.697	1.00
79_F	178_S	1.689	1.00
90_L	97_K	1.683	1.00
196_H	223_V	1.677	1.00
392_R	396_A	1.649	1.00
123_G	126_R	1.644	1.00
59_D	248_M	1.620	1.00
390_V	394_K	1.614	1.00
256_L	286_F	1.591	1.00
182_N	210_Q	1.590	1.00
112_Q	117_E	1.586	1.00
81_R	84_A	1.576	1.00
104_R	108_L	1.562	1.00
142_F	216_A	1.557	1.00
408_H	412_A	1.550	1.00
106_E	110_E	1.549	1.00
85_V	217_L	1.521	1.00
50_T	53_A	1.519	1.00
135_D	162_F	1.515	1.00
20_A	64_L	1.512	1.00
36_E	69_D	1.506	1.00
198_I	225_A	1.506	1.00
413_T	417_L	1.505	1.00
98_C	125_C	1.504	1.00
59_D	62_N	1.498	1.00
89_M	94_T	1.495	1.00
4_K	38_V	1.491	1.00
142_F	212_N	1.490	1.00
390_V	393_D	1.475	1.00
401_W	406_V	1.467	1.00
144_N	212_N	1.467	1.00
232_G	242_H	1.463	1.00
258_E	318_Y	1.461	1.00
225_A	288_L	1.459	1.00
276_I	306_L	1.447	1.00
88_Q	91_E	1.446	1.00
309_H	313_A	1.432	1.00
301_D	304_L	1.429	1.00
128_S	132_H	1.425	1.00
362_R	366_E	1.408	1.00
63_W	251_R	1.398	1.00
190_W	220_P	1.397	1.00
4_K	193_E	1.394	1.00
86_I	90_L	1.392	1.00
5_T	26_S	1.389	1.00
83_N	87_D	1.384	1.00
372_D	375_A	1.382	1.00
265_V	282_M	1.380	1.00
262_N	266_R	1.376	1.00
318_Y	322_H	1.372	1.00
352_K	356_E	1.369	1.00
58_M	72_P	1.362	1.00
309_H	312_N	1.359	1.00
68_W	71_G	1.357	1.00
70_E	73_Y	1.354	1.00
58_M	62_N	1.342	1.00
394_K	412_A	1.340	1.00
286_F	290_A	1.336	1.00
97_K	140_V	1.327	1.00
102_K	106_E	1.316	1.00
376_A	380_L	1.314	1.00
38_V	71_G	1.313	1.00
249_Q	252_D	1.301	1.00
412_A	415_D	1.296	1.00
147_E	165_Q	1.293	1.00
274_Q	281_E	1.285	1.00
85_V	187_V	1.280	1.00
412_A	416_E	1.277	1.00
104_R	122_D	1.276	1.00
388_L	391_V	1.260	1.00
333_D	336_N	1.260	1.00
90_L	140_V	1.257	1.00
24_L	66_L	1.254	1.00
22_T	200_G	1.254	1.00
95_A	140_V	1.252	1.00
398_I	406_V	1.245	1.00
104_R	124_R	1.245	1.00
104_R	107_A	1.244	1.00
92_E	218_K	1.238	1.00
186_V	213_I	1.238	1.00
114_A	119_P	1.234	1.00
317_E	331_N	1.232	1.00
348_G	351_C	1.226	1.00
55_E	58_M	1.225	1.00
321_T	337_G	1.220	1.00
125_C	128_S	1.218	1.00
155_Q	288_L	1.208	1.00
400_D	405_N	1.203	1.00
52_E	55_E	1.200	1.00
88_Q	218_K	1.198	1.00
324_Q	337_G	1.190	1.00
36_E	70_E	1.188	1.00
29_F	196_H	1.180	1.00
211_I	215_K	1.176	1.00
375_A	378_K	1.163	1.00
343_L	364_F	1.162	1.00
90_L	95_A	1.158	1.00
152_F	204_I	1.158	1.00
249_Q	253_D	1.157	1.00
38_V	73_Y	1.154	1.00
27_W	31_R	1.151	1.00
85_V	219_A	1.151	1.00
182_N	206_N	1.151	1.00
100_C	121_Y	1.146	1.00
107_A	110_E	1.138	1.00
51_P	54_I	1.136	1.00
37_F	66_L	1.119	1.00
203_H	206_N	1.117	1.00
99_Y	137_P	1.115	1.00
75_Q	184_C	1.112	1.00
318_Y	321_T	1.109	1.00
261_L	279_R	1.107	1.00
315_P	331_N	1.105	1.00
134_D	162_F	1.104	1.00
203_H	210_Q	1.101	1.00
148_G	164_N	1.100	1.00
126_R	143_A	1.099	1.00
95_A	172_I	1.099	1.00
80_D	83_N	1.099	1.00
99_Y	136_E	1.097	1.00
128_S	133_A	1.097	1.00
393_D	397_A	1.096	1.00
324_Q	328_E	1.092	1.00
128_S	131_H	1.089	1.00
104_R	125_C	1.088	1.00
123_G	143_A	1.083	1.00
281_E	285_Y	1.074	1.00
85_V	88_Q	1.070	1.00
320_A	341_A	1.067	1.00
110_E	114_A	1.065	1.00
157_R	213_I	1.064	1.00
4_K	70_E	1.064	1.00
31_R	69_D	1.061	1.00
58_M	68_W	1.049	1.00
27_W	37_F	1.047	1.00
142_F	213_I	1.041	1.00
91_E	94_T	1.040	1.00
324_Q	327_I	1.039	1.00
29_F	198_I	1.033	1.00
3_I	29_F	1.031	1.00
86_I	95_A	1.027	1.00
281_E	284_K	1.024	1.00
112_Q	116_G	1.023	1.00
112_Q	115_K	1.021	0.99
122_D	125_C	1.018	0.99
111_E	114_A	1.017	0.99
22_T	26_S	1.013	0.99
84_A	91_E	1.012	0.99
394_K	397_A	1.009	0.99
75_Q	188_D	1.004	0.99
411_Q	415_D	1.002	0.99
279_R	283_I	1.001	0.99
345_K	348_G	0.995	0.99
347_L	357_M	0.993	0.99
82_Y	184_C	0.993	0.99
90_L	129_H	0.990	0.99
78_R	82_Y	0.982	0.99
98_C	105_L	0.981	0.99
46_L	76_T	0.981	0.99
92_E	216_A	0.980	0.99
354_L	392_R	0.979	0.99
405_N	408_H	0.978	0.99
14_Y	52_E	0.977	0.99
182_N	203_H	0.973	0.99
252_D	329_Q	0.968	0.99
258_E	286_F	0.967	0.99
404_E	408_H	0.962	0.99
46_L	178_S	0.958	0.99
14_Y	56_A	0.955	0.99
339_Q	343_L	0.955	0.99
42_E	185_V	0.955	0.99
304_L	353_T	0.949	0.99
411_Q	414_A	0.948	0.99
113_M	116_G	0.948	0.99
59_D	251_R	0.947	0.99
311_I	350_R	0.947	0.99
7_F	15_L	0.939	0.99
127_H	133_A	0.937	0.99
76_T	178_S	0.935	0.99
304_L	352_K	0.933	0.99
299_N	386_Q	0.933	0.99
346_L	364_F	0.932	0.99
5_T	29_F	0.927	0.99
87_D	90_L	0.926	0.99
310_Y	313_A	0.919	0.99
386_Q	389_E	0.916	0.99
84_A	87_D	0.912	0.99
38_V	70_E	0.900	0.99
255_Y	260_L	0.894	0.99
32_N	287_T	0.888	0.99
299_N	334_T	0.884	0.99
356_E	359_Q	0.882	0.99
4_K	71_G	0.880	0.98
113_M	119_P	0.880	0.98
343_L	361_C	0.877	0.98
342_D	345_K	0.873	0.98
314_L	322_H	0.870	0.98
256_L	259_A	0.870	0.98
79_F	83_N	0.869	0.98
330_E	358_A	0.868	0.98
100_C	124_R	0.868	0.98
233_D	301_D	0.867	0.98
78_R	81_R	0.862	0.98
81_R	88_Q	0.858	0.98
151_V	206_N	0.858	0.98
31_R	67_E	0.853	0.98
3_I	196_H	0.853	0.98
320_A	324_Q	0.850	0.98
162_F	208_P	0.848	0.98
316_P	345_K	0.847	0.98
347_L	361_C	0.843	0.98
389_E	393_D	0.843	0.98
404_E	407_H	0.842	0.98
91_E	130_E	0.842	0.98
322_H	325_W	0.829	0.98
162_F	172_I	0.828	0.98
280_E	283_I	0.827	0.98
335_R	338_P	0.826	0.98
174_R	184_C	0.826	0.98
14_Y	245_V	0.825	0.98
121_Y	124_R	0.825	0.98
214_L	217_L	0.820	0.98
68_W	72_P	0.817	0.98
83_N	130_E	0.811	0.97
22_T	198_I	0.810	0.97
390_V	416_E	0.808	0.97
19_G	202_D	0.808	0.97
60_G	248_M	0.808	0.97
108_L	124_R	0.806	0.97
152_F	211_I	0.805	0.97
288_L	323_L	0.805	0.97
258_E	322_H	0.804	0.97
403_A	407_H	0.801	0.97
142_F	172_I	0.798	0.97
370_E	373_A	0.793	0.97
100_C	105_L	0.789	0.97
391_V	396_A	0.789	0.97
356_E	360_S	0.784	0.97
111_E	117_E	0.784	0.97
157_R	202_D	0.782	0.97
288_L	291_V	0.780	0.97
22_T	25_Y	0.776	0.97
187_V	217_L	0.775	0.97
112_Q	119_P	0.774	0.97
213_I	217_L	0.773	0.97
244_A	253_D	0.768	0.96
26_S	29_F	0.768	0.96
88_Q	94_T	0.768	0.96
207_T	224_Y	0.767	0.96
300_T	304_L	0.764	0.96
374_D	378_K	0.763	0.96
387_P	413_T	0.762	0.96
258_E	290_A	0.761	0.96
277_F	282_M	0.760	0.96
401_W	405_N	0.759	0.96
337_G	341_A	0.758	0.96
105_L	121_Y	0.758	0.96
163_S	166_E	0.757	0.96
61_M	66_L	0.757	0.96
266_R	282_M	0.755	0.96
306_L	310_Y	0.754	0.96
319_V	323_L	0.750	0.96
32_N	283_I	0.750	0.96
339_Q	342_D	0.749	0.96
287_T	290_A	0.749	0.96
296_S	355_K	0.749	0.96
323_L	357_M	0.749	0.96
334_T	337_G	0.747	0.96
261_L	282_M	0.747	0.96
99_Y	120_R	0.746	0.96
353_T	356_E	0.746	0.96
277_F	281_E	0.745	0.96
103_E	106_E	0.743	0.96
56_A	248_M	0.742	0.96
394_K	409_A	0.740	0.96
336_N	339_Q	0.740	0.96
250_Y	260_L	0.739	0.96
256_L	307_N	0.739	0.96
391_V	394_K	0.737	0.96
235_G	367_D	0.736	0.95
267_L	296_S	0.736	0.95
150_V	212_N	0.736	0.95
387_P	417_L	0.734	0.95
7_F	57_I	0.732	0.95
262_N	282_M	0.732	0.95
406_V	409_A	0.731	0.95
255_Y	303_L	0.730	0.95
276_I	310_Y	0.725	0.95
328_E	333_D	0.725	0.95
206_N	210_Q	0.722	0.95
155_Q	196_H	0.720	0.95
77_K	166_E	0.720	0.95
30_A	35_G	0.720	0.95
27_W	67_E	0.718	0.95
120_R	123_G	0.717	0.95
198_I	288_L	0.717	0.95
61_M	229_M	0.716	0.95
46_L	49_S	0.712	0.95
127_H	143_A	0.710	0.95
391_V	410_I	0.705	0.94
232_G	236_K	0.702	0.94
38_V	69_D	0.701	0.94
143_A	146_Q	0.701	0.94
100_C	104_R	0.701	0.94
311_I	314_L	0.701	0.94
170_L	209_R	0.700	0.94
82_Y	187_V	0.699	0.94
371_F	375_A	0.698	0.94
142_F	170_L	0.698	0.94
174_R	178_S	0.695	0.94
382_P	385_R	0.694	0.94
186_V	214_L	0.694	0.94
234_D	242_H	0.693	0.94
21_R	230_I	0.693	0.94
47_E	50_T	0.691	0.94
46_L	176_D	0.690	0.94
178_S	202_D	0.689	0.94
214_L	219_A	0.688	0.94
201_E	229_M	0.688	0.94
86_I	183_F	0.688	0.94
394_K	413_T	0.688	0.94
3_I	33_H	0.687	0.93
83_N	177_G	0.686	0.93
375_A	379_H	0.683	0.93
187_V	219_A	0.681	0.93
272_G	290_A	0.677	0.93
407_H	415_D	0.674	0.93
73_Y	192_M	0.673	0.93
155_Q	225_A	0.672	0.93
328_E	331_N	0.671	0.93
334_T	338_P	0.671	0.93
409_A	413_T	0.670	0.93
103_E	107_A	0.670	0.93
99_Y	121_Y	0.668	0.93
205_N	208_P	0.664	0.92
157_R	204_I	0.664	0.92
152_F	208_P	0.664	0.92
197_V	207_T	0.664	0.92
214_L	222_P	0.663	0.92
190_W	193_E	0.662	0.92
164_N	167_L	0.659	0.92
106_E	113_M	0.659	0.92
385_R	389_E	0.657	0.92
317_E	329_Q	0.656	0.92
61_M	200_G	0.653	0.92
409_A	412_A	0.653	0.92
144_N	167_L	0.651	0.92
187_V	191_D	0.650	0.91
398_I	405_N	0.649	0.91
22_T	238_L	0.649	0.91
388_L	392_R	0.647	0.91
250_Y	259_A	0.646	0.91
111_E	116_G	0.644	0.91
54_I	165_Q	0.641	0.91
215_K	218_K	0.641	0.91
131_H	138_C	0.640	0.91
398_I	409_A	0.640	0.91
258_E	314_L	0.639	0.91
49_S	53_A	0.639	0.91
319_V	344_V	0.638	0.91
406_V	410_I	0.635	0.91
255_Y	279_R	0.634	0.90
320_A	344_V	0.632	0.90
97_K	136_E	0.631	0.90
150_V	211_I	0.630	0.90
212_N	215_K	0.629	0.90
317_E	321_T	0.627	0.90
220_P	223_V	0.627	0.90
405_N	409_A	0.625	0.90
174_R	210_Q	0.618	0.89
294_S	320_A	0.618	0.89
330_E	359_Q	0.616	0.89
85_V	183_F	0.615	0.89
391_V	395_L	0.615	0.89
322_H	354_L	0.615	0.89
305_W	309_H	0.613	0.89
190_W	217_L	0.613	0.89
244_A	249_Q	0.612	0.89
387_P	390_V	0.612	0.89
104_R	136_E	0.611	0.89
377_K	381_R	0.610	0.89
381_R	384_A	0.610	0.89
333_D	337_G	0.609	0.89
17_V	298_F	0.608	0.89
184_C	190_W	0.608	0.89
325_W	328_E	0.607	0.88
338_P	342_D	0.607	0.88
410_I	413_T	0.606	0.88
112_Q	120_R	0.606	0.88
321_T	324_Q	0.605	0.88
232_G	243_G	0.604	0.88
274_Q	285_Y	0.604	0.88
85_V	186_V	0.604	0.88
232_G	244_A	0.601	0.88
41_I	54_I	0.599	0.88
186_V	206_N	0.597	0.88
408_H	411_Q	0.597	0.88
316_P	320_A	0.595	0.87
24_L	261_L	0.593	0.87
311_I	354_L	0.592	0.87
112_Q	150_V	0.592	0.87
78_R	188_D	0.591	0.87
253_D	300_T	0.591	0.87
266_R	278_T	0.590	0.87
396_A	400_D	0.589	0.87
162_F	169_D	0.589	0.87
242_H	245_V	0.589	0.87
236_K	242_H	0.589	0.87
402_T	406_V	0.588	0.87
341_A	345_K	0.588	0.87
386_Q	390_V	0.588	0.87
184_C	188_D	0.587	0.87
88_Q	219_A	0.587	0.87
75_Q	82_Y	0.586	0.87
381_R	385_R	0.585	0.87
15_L	22_T	0.585	0.87
366_E	369_A	0.585	0.87
152_F	207_T	0.584	0.87
264_L	267_L	0.583	0.86
398_I	401_W	0.583	0.86
15_L	20_A	0.583	0.86
407_H	410_I	0.583	0.86
168_D	209_R	0.582	0.86
108_L	112_Q	0.580	0.86
355_K	392_R	0.579	0.86
382_P	386_Q	0.579	0.86
391_V	413_T	0.579	0.86
119_P	122_D	0.579	0.86
28_L	265_V	0.577	0.86
49_S	52_E	0.576	0.86
152_F	162_F	0.576	0.86
314_L	319_V	0.576	0.86
206_N	213_I	0.576	0.86
156_I	225_A	0.576	0.86
84_A	191_D	0.575	0.86
76_T	79_F	0.574	0.86
49_S	203_H	0.573	0.85
105_L	109_R	0.572	0.85
24_L	28_L	0.572	0.85
174_R	203_H	0.572	0.85
123_G	146_Q	0.571	0.85
214_L	221_V	0.571	0.85
248_M	252_D	0.570	0.85
371_F	374_D	0.570	0.85
370_E	374_D	0.568	0.85
394_K	398_I	0.568	0.85
73_Y	77_K	0.566	0.85
190_W	214_L	0.566	0.85
351_C	360_S	0.566	0.85
6_R	9_P	0.566	0.85
5_T	37_F	0.563	0.84
356_E	387_P	0.560	0.84
114_A	146_Q	0.560	0.84
366_E	371_F	0.560	0.84
197_V	224_Y	0.558	0.84
97_K	137_P	0.557	0.84
23_A	66_L	0.557	0.84
338_P	341_A	0.556	0.84
368_F	371_F	0.554	0.84
121_Y	126_R	0.554	0.84
202_D	210_Q	0.552	0.83
6_R	11_P	0.551	0.83
54_I	58_M	0.551	0.83
321_T	328_E	0.550	0.83
390_V	413_T	0.548	0.83
274_Q	277_F	0.548	0.83
162_F	166_E	0.547	0.83
407_H	414_A	0.547	0.83
255_Y	259_A	0.546	0.83
156_I	291_V	0.544	0.82
360_S	363_Y	0.544	0.82
266_R	271_H	0.544	0.82
119_P	123_G	0.542	0.82
127_H	130_E	0.542	0.82
262_N	281_E	0.542	0.82
99_Y	135_D	0.542	0.82
206_N	209_R	0.541	0.82
63_W	257_P	0.540	0.82
207_T	211_I	0.539	0.82
7_F	21_R	0.539	0.82
361_C	365_Y	0.539	0.82
133_A	137_P	0.539	0.82
105_L	139_V	0.539	0.82
87_D	97_K	0.538	0.82
170_L	213_I	0.538	0.82
9_P	13_G	0.537	0.82
15_L	56_A	0.536	0.82
57_I	60_G	0.535	0.81
182_N	209_R	0.535	0.81
253_D	355_K	0.535	0.81
225_A	291_V	0.534	0.81
69_D	73_Y	0.534	0.81
32_N	284_K	0.532	0.81
312_N	349_E	0.532	0.81
94_T	215_K	0.532	0.81
307_N	354_L	0.531	0.81
262_N	286_F	0.531	0.81
258_E	279_R	0.531	0.81
410_I	414_A	0.530	0.81
119_P	126_R	0.530	0.81
47_E	51_P	0.530	0.81
46_L	79_F	0.529	0.81
321_T	327_I	0.528	0.81
233_D	300_T	0.527	0.80
91_E	123_G	0.526	0.80
19_G	227_V	0.526	0.80
174_R	202_D	0.526	0.80
99_Y	134_D	0.525	0.80
326_H	330_E	0.524	0.80
73_Y	82_Y	0.524	0.80
191_D	219_A	0.524	0.80
395_L	398_I	0.524	0.80
164_N	212_N	0.523	0.80
278_T	310_Y	0.523	0.80
19_G	22_T	0.523	0.80
155_Q	289_N	0.521	0.80
374_D	379_H	0.521	0.80
209_R	232_G	0.520	0.80
28_L	282_M	0.520	0.80
79_F	82_Y	0.519	0.79
400_D	408_H	0.519	0.79
5_T	198_I	0.518	0.79
128_S	136_E	0.516	0.79
49_S	210_Q	0.515	0.79
373_A	377_K	0.515	0.79
410_I	417_L	0.515	0.79
345_K	349_E	0.515	0.79
322_H	326_H	0.515	0.79
339_Q	364_F	0.514	0.79
347_L	360_S	0.514	0.79
38_V	72_P	0.513	0.79
66_L	261_L	0.513	0.79
319_V	322_H	0.512	0.79
33_H	287_T	0.512	0.79
377_K	380_L	0.512	0.79
157_R	183_F	0.511	0.78
149_S	164_N	0.510	0.78
109_R	119_P	0.510	0.78
151_V	205_N	0.509	0.78
365_Y	379_H	0.509	0.78
157_R	209_R	0.508	0.78
372_D	379_H	0.507	0.78
151_V	208_P	0.506	0.78
266_R	292_S	0.504	0.77
17_V	260_L	0.504	0.77
187_V	213_I	0.503	0.77
4_K	73_Y	0.503	0.77
120_R	124_R	0.501	0.77
188_D	206_N	0.500	0.77
51_P	74_Y	0.500	0.77
207_T	226_H	0.500	0.77

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2ja2A	1	0.9745	100	0.233	Contact Map
2cfoA	1	0.9979	100	0.237	Contact Map
4griA	1	0.983	100	0.241	Contact Map
1j09A	1	0.9618	100	0.25	Contact Map
4g6zA	1	0.7877	100	0.257	Contact Map
3al0C	1	0.9512	100	0.259	Contact Map
3afhA	1	0.9512	100	0.262	Contact Map
2o5rA	1	0.9575	100	0.285	Contact Map
2hz7A	1	0.879	100	0.466	Contact Map
4h3sA	1	0.9406	100	0.477	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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