ATKB - ECOLI - GREMLIN Contacts

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ATKB - Potassium-transporting ATPase B chain

UniProt:	P03960	Sequences: MSRKQLALFEPTLVVQALKEAVKKLNPQAQWRNPVMFIVWIGSLLTTCISIAMASGAMPGNALFSAAISGWLWITVLFANFAEALAEGRSKAQANSLKGVKKTAFARKLREPKYGAAADKVPADQLRKGDIVLVEAGDIIPCDGEVIEGGASVDESAITGESAPVIRESGGDFASVTGGTRILSDWLVIECSVNPGETFLDRMIAMVEGAQRRKTPNEIALTILLIALTIVFLLATATLWPFSAWGGNAVSVTVLVALLVCLIPTTIGGLLSAIGVAGMSRMLGANVIATSGRAVEAAGDVDVLLLDKTGTITLGNRQASEFIPAQGVDEKTLADAAQLASLADETPEGRSIVILAKQRFNLRERDVQSLHATFVPFTAQSRMSGINIDNRMIRKGSVDAIRRHVEANGGHFPTDVDQKVDQVARQGATPLVVVEGSRVLGVIALKDIVKGGIKERFAQLRKMGIKTVMITGDNRLTAAAIAAEAGVDDFLAEATPEAKLALIRQYQAEGRLVAMTGDGTNDAPALAQADVAVAMNSGTQAAKEAGNMVDLDSNPTKLIEVVHIGKQMLMTRGSLTTFSIANDVAKYFAIIPAAFAATYPQLNALNIMCLHSPDSAILSAVIFNALIIVFLIPLALKGVSYKPLTASAMLRRNLWIYGLGGLLVPFIGIKVIDLLLTVCGLV	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10514
Length:	682 (561)
Sequences:	23066 (13631)
Seq/√Len:	575.5

ECOLI - ATKB ATMA COPA ATZN
BACSU - ATCL COPA ZOSA CADA
HALSA - ATKB Q9HRH2 Q9HSN5 Q9HN90
SULSO - Q97VH4 Q97UU7

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
144_G	189_I	4.270	1.00
302_D	511_R	4.238	1.00
475_R	479_A	4.108	1.00
145_E	190_E	3.390	1.00
452_G	554_N	3.343	1.00
151_A	187_L	3.298	1.00
105_F	120_K	3.290	1.00
504_R	528_Q	3.270	1.00
301_V	514_A	3.213	1.00
148_E	188_V	3.049	1.00
507_Q	528_Q	3.037	1.00
502_L	505_Q	2.987	1.00
109_L	188_V	2.788	1.00
435_E	440_L	2.729	1.00
471_T	478_A	2.694	1.00
110_R	119_D	2.661	1.00
498_A	501_A	2.653	1.00
475_R	493_E	2.639	1.00
314_L	451_G	2.621	1.00
376_P	384_S	2.605	1.00
107_R	120_K	2.592	1.00
482_A	490_F	2.582	1.00
419_K	422_Q	2.563	1.00
340_A	385_G	2.555	1.00
321_E	428_A	2.554	1.00
319_A	355_L	2.522	1.00
314_L	448_I	2.490	1.00
176_V	189_I	2.464	1.00
454_K	458_A	2.461	1.00
355_L	359_R	2.455	1.00
479_A	483_A	2.428	1.00
285_A	560_E	2.420	1.00
131_I	147_I	2.416	1.00
142_C	191_C	2.398	1.00
131_I	188_V	2.360	1.00
330_E	359_R	2.358	1.00
458_A	462_K	2.356	1.00
491_L	502_L	2.336	1.00
151_A	182_I	2.305	1.00
118_A	133_L	2.285	1.00
514_A	533_V	2.259	1.00
110_R	117_A	2.258	1.00
333_L	441_G	2.235	1.00
112_P	117_A	2.229	1.00
108_K	119_D	2.134	1.00
459_Q	563_H	2.130	1.00
131_I	190_E	2.123	1.00
370_L	389_D	2.120	1.00
466_K	489_D	2.088	1.00
423_V	444_A	2.084	1.00
109_L	118_A	2.083	1.00
507_Q	530_D	2.037	1.00
147_I	190_E	2.034	1.00
240_W	255_L	2.032	1.00
339_L	370_L	2.010	1.00
312_I	485_A	2.003	1.00
107_R	138_D	2.001	1.00
381_S	403_R	1.995	1.00
132_V	144_G	1.991	1.00
133_L	188_V	1.975	1.00
107_R	118_A	1.961	1.00
391_R	436_G	1.960	1.00
144_G	176_V	1.921	1.00
425_R	476_L	1.882	1.00
321_E	426_Q	1.848	1.00
432_V	439_V	1.827	1.00
449_V	485_A	1.807	1.00
455_E	459_Q	1.803	1.00
305_L	470_I	1.800	1.00
140_I	153_V	1.793	1.00
374_F	387_N	1.790	1.00
463_M	563_H	1.768	1.00
394_R	404_H	1.768	1.00
466_K	511_R	1.752	1.00
355_L	358_Q	1.750	1.00
319_A	443_I	1.734	1.00
332_T	335_D	1.727	1.00
146_V	187_L	1.724	1.00
304_L	514_A	1.718	1.00
505_Q	509_E	1.705	1.00
336_A	393_I	1.702	1.00
110_R	130_D	1.697	1.00
504_R	508_A	1.692	1.00
430_P	442_V	1.687	1.00
305_L	506_Y	1.687	1.00
129_G	190_E	1.683	1.00
175_S	192_S	1.672	1.00
145_E	192_S	1.670	1.00
152_S	166_I	1.667	1.00
155_E	167_R	1.666	1.00
470_I	502_L	1.665	1.00
282_M	564_I	1.658	1.00
417_D	421_D	1.651	1.00
384_S	392_M	1.626	1.00
420_V	432_V	1.624	1.00
461_R	488_D	1.621	1.00
132_V	189_I	1.618	1.00
422_Q	426_Q	1.614	1.00
205_A	209_G	1.590	1.00
470_I	494_A	1.580	1.00
350_R	354_I	1.554	1.00
107_R	135_E	1.552	1.00
126_L	132_V	1.549	1.00
500_L	528_Q	1.548	1.00
303_V	468_V	1.545	1.00
126_L	142_C	1.542	1.00
454_K	484_E	1.536	1.00
126_L	191_C	1.534	1.00
153_V	182_I	1.531	1.00
354_I	358_Q	1.530	1.00
421_D	425_R	1.529	1.00
461_R	467_T	1.528	1.00
537_S	553_S	1.524	1.00
401_I	434_V	1.521	1.00
223_I	227_A	1.513	1.00
469_M	478_A	1.511	1.00
320_S	446_K	1.510	1.00
303_V	511_R	1.497	1.00
305_L	503_I	1.487	1.00
128_K	194_N	1.483	1.00
501_A	504_R	1.482	1.00
455_E	556_T	1.478	1.00
337_A	433_V	1.470	1.00
338_Q	356_A	1.469	1.00
121_V	125_Q	1.466	1.00
428_A	444_A	1.459	1.00
352_I	443_I	1.458	1.00
394_R	437_S	1.445	1.00
302_D	512_L	1.438	1.00
318_Q	354_I	1.437	1.00
456_R	559_I	1.436	1.00
323_I	419_K	1.434	1.00
168_E	171_G	1.434	1.00
479_A	490_F	1.432	1.00
111_E	117_A	1.427	1.00
446_K	484_E	1.416	1.00
105_F	122_P	1.414	1.00
378_T	400_A	1.406	1.00
158_I	177_T	1.405	1.00
395_K	433_V	1.402	1.00
314_L	318_Q	1.399	1.00
431_L	445_L	1.397	1.00
122_P	125_Q	1.388	1.00
49_I	52_A	1.384	1.00
377_F	380_Q	1.382	1.00
452_G	556_T	1.379	1.00
459_Q	462_K	1.378	1.00
552_D	557_K	1.368	1.00
452_G	455_E	1.366	1.00
145_E	175_S	1.364	1.00
289_A	548_M	1.364	1.00
175_S	193_V	1.361	1.00
380_Q	383_M	1.358	1.00
501_A	505_Q	1.357	1.00
144_G	192_S	1.356	1.00
391_R	435_E	1.353	1.00
397_S	400_A	1.353	1.00
154_D	183_L	1.352	1.00
234_L	238_T	1.351	1.00
281_R	285_A	1.349	1.00
243_S	251_S	1.342	1.00
132_V	191_C	1.339	1.00
46_T	49_I	1.329	1.00
601_Q	604_A	1.327	1.00
455_E	458_A	1.326	1.00
278_G	568_M	1.313	1.00
320_S	428_A	1.312	1.00
214_K	222_T	1.306	1.00
394_R	434_V	1.302	1.00
577_T	581_A	1.290	1.00
331_K	359_R	1.289	1.00
418_Q	422_Q	1.287	1.00
47_T	51_I	1.286	1.00
328_V	440_L	1.285	1.00
393_I	435_E	1.285	1.00
534_A	546_G	1.280	1.00
607_I	614_D	1.278	1.00
418_Q	421_D	1.276	1.00
533_V	558_L	1.274	1.00
394_R	401_I	1.273	1.00
108_K	130_D	1.272	1.00
240_W	244_A	1.268	1.00
291_S	547_N	1.266	1.00
526_L	542_A	1.264	1.00
504_R	507_Q	1.262	1.00
471_T	492_A	1.260	1.00
150_G	166_I	1.253	1.00
193_V	197_E	1.246	1.00
478_A	492_A	1.240	1.00
45_L	49_I	1.239	1.00
153_V	187_L	1.237	1.00
610_L	614_D	1.233	1.00
421_D	476_L	1.231	1.00
468_V	489_D	1.227	1.00
416_V	439_V	1.225	1.00
354_I	357_K	1.223	1.00
300_D	512_L	1.219	1.00
318_Q	448_I	1.210	1.00
621_V	624_N	1.208	1.00
52_A	56_G	1.200	1.00
491_L	505_Q	1.197	1.00
505_Q	508_A	1.196	1.00
398_V	402_R	1.195	1.00
133_L	186_W	1.194	1.00
233_L	237_A	1.190	1.00
241_P	245_W	1.190	1.00
608_M	615_S	1.189	1.00
414_T	418_Q	1.186	1.00
387_N	392_M	1.185	1.00
150_G	168_E	1.182	1.00
153_V	176_V	1.182	1.00
238_T	242_F	1.179	1.00
108_K	121_V	1.173	1.00
614_D	617_I	1.171	1.00
378_T	384_S	1.167	1.00
134_V	140_I	1.166	1.00
274_I	571_T	1.163	1.00
81_F	85_L	1.161	1.00
336_A	440_L	1.157	1.00
48_C	52_A	1.152	1.00
465_I	562_V	1.151	1.00
46_T	50_S	1.144	1.00
378_T	381_S	1.140	1.00
607_I	610_L	1.138	1.00
132_V	141_P	1.136	1.00
306_L	467_T	1.132	1.00
337_A	443_I	1.120	1.00
433_V	441_G	1.120	1.00
53_M	56_G	1.119	1.00
412_F	415_D	1.118	1.00
333_L	337_A	1.117	1.00
109_L	133_L	1.113	1.00
339_L	369_S	1.113	1.00
299_G	569_L	1.111	1.00
423_V	428_A	1.108	1.00
315_G	447_D	1.108	1.00
615_S	619_S	1.108	1.00
323_I	423_V	1.105	1.00
319_A	445_L	1.105	1.00
569_L	573_G	1.103	1.00
413_P	417_D	1.102	1.00
401_I	405_V	1.101	1.00
512_L	530_D	1.099	1.00
335_D	339_L	1.099	1.00
475_R	492_A	1.098	1.00
384_S	394_R	1.096	1.00
281_R	284_G	1.095	1.00
246_G	249_A	1.093	1.00
401_I	406_E	1.092	1.00
324_P	330_E	1.090	1.00
491_L	494_A	1.089	1.00
606_N	614_D	1.080	1.00
194_N	197_E	1.080	1.00
375_V	383_M	1.079	1.00
334_A	355_L	1.078	1.00
414_T	417_D	1.077	1.00
152_S	184_S	1.070	1.00
239_L	254_V	1.069	1.00
202_R	497_E	1.068	1.00
383_M	404_H	1.066	1.00
127_R	130_D	1.062	1.00
297_A	512_L	1.061	1.00
306_L	312_I	1.059	1.00
316_N	354_I	1.058	1.00
92_A	95_N	1.055	1.00
497_E	501_A	1.054	1.00
419_K	423_V	1.054	1.00
373_T	387_N	1.054	1.00
85_L	89_R	1.053	1.00
348_E	445_L	1.052	1.00
110_R	121_V	1.051	1.00
398_V	432_V	1.051	1.00
480_A	484_E	1.050	1.00
329_D	332_T	1.049	1.00
312_I	449_V	1.048	1.00
527_A	545_A	1.045	1.00
325_A	328_V	1.044	1.00
385_G	392_M	1.042	1.00
324_P	333_L	1.042	1.00
468_V	506_Y	1.041	1.00
134_V	189_I	1.039	1.00
370_L	388_I	1.037	1.00
611_H	615_S	1.035	1.00
135_E	138_D	1.031	1.00
621_V	625_A	1.031	1.00
335_D	370_L	1.029	1.00
47_T	50_S	1.028	1.00
341_S	349_G	1.027	1.00
503_I	515_M	1.026	1.00
324_P	441_G	1.025	1.00
202_R	205_A	1.023	1.00
463_M	566_K	1.022	1.00
590_I	595_F	1.021	1.00
402_R	417_D	1.021	1.00
380_Q	384_S	1.019	1.00
199_F	202_R	1.018	1.00
380_Q	385_G	1.017	1.00
596_A	600_P	1.016	1.00
321_E	444_A	1.007	1.00
145_E	170_G	1.007	1.00
303_V	506_Y	1.001	1.00
49_I	53_M	0.996	1.00
219_I	223_I	0.995	1.00
460_L	559_I	0.989	1.00
140_I	176_V	0.984	1.00
452_G	456_R	0.982	1.00
478_A	490_F	0.980	1.00
606_N	615_S	0.980	1.00
299_G	565_G	0.978	1.00
287_V	557_K	0.977	1.00
325_A	416_V	0.977	1.00
406_E	436_G	0.974	1.00
420_V	424_A	0.972	1.00
393_I	440_L	0.972	1.00
317_R	348_E	0.972	1.00
608_M	614_D	0.970	1.00
318_Q	358_Q	0.969	1.00
459_Q	463_M	0.967	1.00
146_V	153_V	0.966	1.00
434_V	437_S	0.966	1.00
297_A	530_D	0.963	1.00
394_R	400_A	0.962	1.00
590_I	593_A	0.959	1.00
186_W	343_A	0.959	1.00
571_T	574_S	0.955	1.00
179_G	200_L	0.954	1.00
109_L	131_I	0.953	1.00
612_S	615_S	0.943	1.00
562_V	566_K	0.942	1.00
400_A	404_H	0.941	1.00
458_A	461_R	0.940	1.00
494_A	498_A	0.939	1.00
335_D	389_D	0.936	1.00
424_A	476_L	0.935	1.00
191_C	194_N	0.934	1.00
398_V	420_V	0.933	1.00
453_I	457_F	0.931	1.00
110_R	127_R	0.928	1.00
146_V	189_I	0.925	1.00
148_E	169_S	0.918	1.00
535_M	538_G	0.914	1.00
146_V	176_V	0.913	1.00
457_F	461_R	0.912	1.00
608_M	611_H	0.912	1.00
393_I	433_V	0.912	1.00
52_A	55_S	0.911	1.00
303_V	466_K	0.910	1.00
449_V	481_I	0.910	1.00
500_L	504_R	0.910	1.00
331_K	335_D	0.907	1.00
475_R	490_F	0.907	1.00
608_M	612_S	0.906	1.00
399_D	493_E	0.901	1.00
342_L	371_H	0.898	1.00
146_V	149_G	0.898	1.00
321_E	330_E	0.898	1.00
607_I	615_S	0.898	1.00
96_S	99_G	0.897	1.00
288_I	551_L	0.896	1.00
120_K	138_D	0.896	1.00
432_V	442_V	0.896	1.00
375_V	385_G	0.895	1.00
463_M	559_I	0.895	1.00
244_A	249_A	0.892	1.00
596_A	599_Y	0.891	1.00
328_V	333_L	0.889	1.00
567_Q	570_M	0.888	1.00
597_A	601_Q	0.887	1.00
433_V	443_I	0.886	1.00
48_C	51_I	0.885	1.00
589_A	592_P	0.883	1.00
345_E	377_F	0.881	1.00
333_L	433_V	0.880	1.00
342_L	357_K	0.876	1.00
134_V	182_I	0.876	1.00
127_R	194_N	0.874	1.00
298_A	561_V	0.873	1.00
385_G	394_R	0.868	1.00
301_V	512_L	0.866	1.00
50_S	53_M	0.865	1.00
610_L	615_S	0.865	1.00
247_G	250_V	0.862	1.00
426_Q	484_E	0.859	1.00
396_G	400_A	0.855	1.00
377_F	381_S	0.852	1.00
285_A	563_H	0.851	1.00
322_F	355_L	0.851	1.00
332_T	336_A	0.850	1.00
326_Q	438_R	0.847	1.00
340_A	395_K	0.843	1.00
118_A	188_V	0.842	1.00
615_S	620_A	0.842	1.00
230_I	234_L	0.841	1.00
322_F	443_I	0.840	1.00
422_Q	425_R	0.839	1.00
321_E	423_V	0.837	1.00
221_L	271_L	0.836	1.00
54_A	58_M	0.835	1.00
449_V	454_K	0.835	1.00
108_K	126_L	0.832	1.00
334_A	337_A	0.830	1.00
241_P	244_A	0.828	1.00
298_A	531_V	0.827	1.00
106_A	126_L	0.826	1.00
176_V	187_L	0.824	1.00
49_I	56_G	0.823	1.00
482_A	487_V	0.817	1.00
89_R	92_A	0.816	1.00
92_A	96_S	0.812	1.00
119_D	125_Q	0.811	1.00
123_A	126_L	0.810	1.00
374_F	377_F	0.809	1.00
617_I	620_A	0.809	1.00
286_N	552_D	0.809	1.00
614_D	619_S	0.808	1.00
606_N	610_L	0.807	1.00
425_R	479_A	0.805	1.00
298_A	548_M	0.804	1.00
459_Q	559_I	0.804	1.00
378_T	382_R	0.804	1.00
457_F	487_V	0.803	1.00
489_D	509_E	0.801	1.00
459_Q	556_T	0.797	1.00
298_A	562_V	0.794	1.00
167_R	171_G	0.793	1.00
407_A	414_T	0.793	1.00
355_L	443_I	0.790	1.00
325_A	439_V	0.789	1.00
474_N	493_E	0.788	1.00
195_P	198_T	0.788	1.00
387_N	390_N	0.788	1.00
392_M	437_S	0.786	1.00
47_T	52_A	0.785	1.00
507_Q	513_V	0.782	1.00
157_A	180_T	0.781	1.00
424_A	430_P	0.781	1.00
302_D	510_G	0.780	1.00
466_K	488_D	0.779	1.00
616_A	619_S	0.779	1.00
470_I	491_L	0.778	1.00
140_I	182_I	0.777	1.00
189_I	192_S	0.777	1.00
607_I	611_H	0.776	1.00
415_D	419_K	0.775	1.00
457_F	467_T	0.773	1.00
199_F	497_E	0.772	1.00
615_S	618_L	0.769	1.00
340_A	393_I	0.768	1.00
340_A	383_M	0.767	1.00
153_V	167_R	0.767	1.00
459_Q	560_E	0.765	1.00
463_M	562_V	0.764	1.00
369_S	372_A	0.764	1.00
557_K	560_E	0.762	1.00
469_M	487_V	0.761	1.00
589_A	593_A	0.760	1.00
226_I	230_I	0.759	1.00
88_G	92_A	0.757	1.00
297_A	300_D	0.757	1.00
246_G	250_V	0.756	1.00
570_M	574_S	0.752	1.00
193_V	202_R	0.751	1.00
147_I	188_V	0.747	1.00
228_L	232_F	0.747	1.00
608_M	616_A	0.746	1.00
618_L	621_V	0.745	1.00
437_S	440_L	0.745	1.00
446_K	449_V	0.745	1.00
516_T	558_L	0.744	1.00
610_L	617_I	0.744	1.00
227_A	231_V	0.743	1.00
141_P	189_I	0.742	1.00
323_I	442_V	0.742	1.00
139_I	181_R	0.740	1.00
607_I	617_I	0.740	1.00
291_S	294_A	0.738	1.00
606_N	617_I	0.737	1.00
456_R	556_T	0.736	1.00
401_I	404_H	0.735	1.00
244_A	251_S	0.734	1.00
495_T	498_A	0.733	1.00
338_Q	353_V	0.732	1.00
474_N	477_T	0.732	1.00
526_L	532_A	0.731	1.00
95_N	99_G	0.730	1.00
304_L	516_T	0.727	1.00
106_A	109_L	0.726	1.00
469_M	482_A	0.726	1.00
423_V	426_Q	0.726	1.00
453_I	485_A	0.725	1.00
420_V	442_V	0.724	1.00
603_N	606_N	0.724	1.00
130_D	191_C	0.723	1.00
312_I	457_F	0.723	1.00
400_A	403_R	0.722	1.00
104_A	139_I	0.722	1.00
177_T	180_T	0.721	1.00
155_E	165_V	0.721	1.00
599_Y	602_L	0.720	1.00
477_T	481_I	0.719	1.00
467_T	487_V	0.717	1.00
312_I	453_I	0.716	1.00
592_P	596_A	0.715	1.00
134_V	141_P	0.714	1.00
132_V	142_C	0.713	1.00
109_L	112_P	0.713	1.00
398_V	424_A	0.713	1.00
593_A	596_A	0.712	1.00
158_I	199_F	0.712	1.00
588_F	592_P	0.712	1.00
136_A	182_I	0.710	1.00
304_L	465_I	0.709	1.00
53_M	57_A	0.708	1.00
420_V	430_P	0.708	1.00
600_P	603_N	0.706	1.00
377_F	384_S	0.705	1.00
604_A	611_H	0.704	1.00
45_L	48_C	0.703	1.00
322_F	334_A	0.703	1.00
96_S	541_A	0.701	1.00
476_L	479_A	0.701	1.00
50_S	54_A	0.701	1.00
601_Q	608_M	0.698	1.00
399_D	402_R	0.698	1.00
281_R	564_I	0.696	1.00
298_A	301_V	0.696	1.00
599_Y	604_A	0.695	1.00
398_V	417_D	0.694	1.00
454_K	485_A	0.693	1.00
324_P	328_V	0.692	1.00
293_R	297_A	0.691	1.00
560_E	563_H	0.691	1.00
324_P	329_D	0.689	1.00
128_K	197_E	0.688	1.00
604_A	607_I	0.687	1.00
261_C	590_I	0.685	1.00
477_T	480_A	0.684	1.00
305_L	468_V	0.683	1.00
48_C	56_G	0.683	1.00
374_F	380_Q	0.682	1.00
70_G	74_I	0.682	1.00
90_S	280_S	0.682	1.00
359_R	362_L	0.682	1.00
328_V	332_T	0.681	1.00
251_S	255_L	0.680	1.00
372_A	375_V	0.679	1.00
567_Q	571_T	0.678	1.00
306_L	460_L	0.678	1.00
401_I	432_V	0.676	1.00
240_W	251_S	0.675	1.00
286_N	551_L	0.674	1.00
405_V	434_V	0.674	1.00
439_V	442_V	0.674	1.00
374_F	384_S	0.672	1.00
84_A	88_G	0.672	1.00
106_A	141_P	0.671	1.00
336_A	340_A	0.669	1.00
301_V	562_V	0.668	1.00
456_R	555_P	0.668	1.00
105_F	108_K	0.668	1.00
155_E	180_T	0.668	1.00
205_A	208_E	0.667	1.00
136_A	151_A	0.667	1.00
382_R	385_G	0.667	1.00
73_W	77_L	0.667	1.00
426_Q	483_A	0.666	1.00
153_V	180_T	0.666	1.00
331_K	362_L	0.666	1.00
135_E	186_W	0.666	1.00
457_F	485_A	0.665	1.00
304_L	467_T	0.664	1.00
468_V	491_L	0.663	1.00
99_G	104_A	0.663	1.00
518_D	521_N	0.662	1.00
336_A	435_E	0.661	1.00
275_G	296_E	0.661	1.00
182_I	187_L	0.660	1.00
607_I	616_A	0.660	1.00
146_V	171_G	0.659	1.00
46_T	52_A	0.657	1.00
289_A	561_V	0.657	1.00
608_M	617_I	0.657	1.00
162_S	477_T	0.652	1.00
372_A	389_D	0.652	1.00
118_A	135_E	0.652	1.00
340_A	433_V	0.651	1.00
599_Y	603_N	0.651	1.00
306_L	558_L	0.650	1.00
392_M	395_K	0.650	1.00
334_A	356_A	0.649	1.00
343_A	353_V	0.649	1.00
45_L	52_A	0.649	1.00
108_K	132_V	0.647	1.00
242_F	245_W	0.647	1.00
503_I	513_V	0.645	1.00
453_I	456_R	0.643	1.00
377_F	383_M	0.642	1.00
381_S	385_G	0.641	1.00
381_S	399_D	0.640	1.00
600_P	604_A	0.639	1.00
417_D	420_V	0.638	1.00
88_G	91_K	0.638	1.00
606_N	609_C	0.637	1.00
287_V	561_V	0.637	1.00
415_D	418_Q	0.636	1.00
236_T	259_L	0.636	1.00
381_S	495_T	0.635	1.00
604_A	615_S	0.635	1.00
301_V	465_I	0.634	1.00
494_A	502_L	0.634	1.00
224_L	576_T	0.633	1.00
336_A	433_V	0.632	1.00
548_M	561_V	0.631	1.00
107_R	133_L	0.631	1.00
48_C	53_M	0.630	1.00
606_N	619_S	0.630	1.00
413_P	416_V	0.630	1.00
282_M	289_A	0.630	1.00
146_V	151_A	0.627	1.00
382_R	397_S	0.624	1.00
128_K	193_V	0.624	1.00
320_S	484_E	0.624	1.00
206_M	497_E	0.624	1.00
403_R	413_P	0.623	1.00
78_F	82_A	0.623	1.00
337_A	395_K	0.621	1.00
339_L	372_A	0.621	1.00
52_A	57_A	0.620	1.00
610_L	619_S	0.620	1.00
575_L	579_S	0.619	1.00
610_L	620_A	0.618	1.00
237_A	241_P	0.618	1.00
435_E	438_R	0.617	1.00
195_P	201_D	0.617	1.00
198_T	201_D	0.616	1.00
301_V	531_V	0.615	1.00
611_H	618_L	0.614	1.00
152_S	183_L	0.614	1.00
608_M	619_S	0.613	1.00
375_V	380_Q	0.613	1.00
302_D	466_K	0.612	1.00
480_A	483_A	0.611	1.00
46_T	51_I	0.611	1.00
326_Q	415_D	0.611	1.00
159_T	165_V	0.608	1.00
471_T	490_F	0.608	1.00
304_L	460_L	0.607	1.00
134_V	138_D	0.607	1.00
453_I	555_P	0.605	1.00
622_I	625_A	0.605	1.00
604_A	608_M	0.604	1.00
607_I	612_S	0.603	1.00
458_A	486_G	0.603	1.00
69_S	73_W	0.603	1.00
51_I	55_S	0.599	1.00
384_S	404_H	0.598	1.00
142_C	198_T	0.597	1.00
372_A	385_G	0.597	1.00
125_Q	128_K	0.596	1.00
338_Q	369_S	0.596	1.00
280_S	284_G	0.596	1.00
468_V	502_L	0.595	1.00
261_C	586_K	0.595	1.00
472_G	519_G	0.594	1.00
559_I	563_H	0.594	1.00
106_A	123_A	0.593	1.00
278_G	564_I	0.593	1.00
252_V	256_V	0.593	1.00
609_C	614_D	0.593	1.00
379_A	382_R	0.593	1.00
523_A	545_A	0.592	1.00
324_P	327_G	0.592	1.00
543_K	549_V	0.592	1.00
586_K	614_D	0.590	1.00
45_L	50_S	0.590	1.00
299_G	566_K	0.588	1.00
123_A	142_C	0.586	1.00
385_G	388_I	0.585	1.00
335_D	369_S	0.585	1.00
564_I	567_Q	0.585	1.00
55_S	58_M	0.585	1.00
333_L	440_L	0.584	1.00
540_Q	543_K	0.583	1.00
609_C	613_P	0.583	1.00
304_L	562_V	0.583	1.00
305_L	494_A	0.583	1.00
352_I	445_L	0.582	1.00
337_A	352_I	0.582	1.00
54_A	57_A	0.582	1.00
539_T	543_K	0.582	1.00
251_S	254_V	0.582	1.00
57_A	69_S	0.581	1.00
196_G	205_A	0.580	1.00
421_D	424_A	0.580	1.00
565_G	569_L	0.580	1.00
178_G	198_T	0.578	1.00
98_K	543_K	0.578	1.00
609_C	616_A	0.576	1.00
593_A	597_A	0.576	1.00
394_R	406_E	0.576	1.00
392_M	404_H	0.575	1.00
239_L	255_L	0.575	1.00
235_A	595_F	0.573	1.00
450_K	553_S	0.573	1.00
608_M	620_A	0.572	1.00
407_A	412_F	0.572	1.00
339_L	388_I	0.572	1.00
336_A	339_L	0.571	1.00
119_D	130_D	0.571	1.00
183_L	350_R	0.571	1.00
460_L	467_T	0.570	1.00
596_A	601_Q	0.570	1.00
75_T	79_A	0.570	1.00
606_N	612_S	0.570	1.00
609_C	615_S	0.570	1.00
52_A	58_M	0.569	1.00
570_M	573_G	0.569	1.00
388_I	393_I	0.569	1.00
312_I	469_M	0.568	0.99
217_N	569_L	0.567	0.99
605_L	609_C	0.567	0.99
612_S	619_S	0.567	0.99
550_D	557_K	0.567	0.99
214_K	219_I	0.567	0.99
289_A	295_V	0.566	0.99
301_V	304_L	0.566	0.99
254_V	257_A	0.566	0.99
416_V	419_K	0.566	0.99
419_K	442_V	0.565	0.99
534_A	538_G	0.565	0.99
317_R	445_L	0.564	0.99
227_A	230_I	0.564	0.99
149_G	169_S	0.563	0.99
337_A	355_L	0.563	0.99
618_L	622_I	0.563	0.99
223_I	226_I	0.562	0.99
377_F	382_R	0.562	0.99
316_N	350_R	0.562	0.99
134_V	187_L	0.561	0.99
136_A	377_F	0.560	0.99
605_L	615_S	0.560	0.99
147_I	169_S	0.557	0.99
184_S	376_P	0.556	0.99
96_S	284_G	0.556	0.99
460_L	558_L	0.555	0.99
506_Y	509_E	0.554	0.99
325_A	419_K	0.554	0.99
375_V	381_S	0.554	0.99
46_T	53_M	0.553	0.99
302_D	305_L	0.551	0.99
146_V	167_R	0.551	0.99
350_R	353_V	0.550	0.99
314_L	452_G	0.549	0.99
334_A	359_R	0.549	0.99
376_P	380_Q	0.549	0.99
616_A	620_A	0.548	0.99
48_C	57_A	0.548	0.99
237_A	240_W	0.548	0.99
320_S	444_A	0.547	0.99
423_V	430_P	0.547	0.99
139_I	154_D	0.545	0.99
322_F	330_E	0.545	0.99
271_L	572_R	0.543	0.99
580_I	584_V	0.541	0.99
149_G	187_L	0.541	0.99
193_V	199_F	0.540	0.99
280_S	283_L	0.539	0.99
236_T	240_W	0.539	0.99
139_I	544_E	0.538	0.99
105_F	110_R	0.537	0.99
108_K	127_R	0.537	0.99
46_T	57_A	0.536	0.99
318_Q	446_K	0.536	0.99
402_R	405_V	0.536	0.99
96_S	544_E	0.536	0.99
319_A	352_I	0.535	0.99
213_R	507_Q	0.535	0.99
571_T	625_A	0.534	0.99
49_I	57_A	0.533	0.99
607_I	619_S	0.532	0.99
49_I	55_S	0.532	0.99
318_Q	355_L	0.531	0.99
302_D	513_V	0.531	0.99
491_L	506_Y	0.531	0.99
593_A	600_P	0.531	0.99
140_I	187_L	0.529	0.99
606_N	616_A	0.529	0.99
611_H	614_D	0.529	0.99
617_I	621_V	0.529	0.99
405_V	439_V	0.529	0.99
321_E	422_Q	0.528	0.99
592_P	595_F	0.527	0.99
146_V	168_E	0.527	0.99
232_F	262_L	0.526	0.99
322_F	333_L	0.526	0.99
108_K	112_P	0.526	0.99
335_D	362_L	0.525	0.99
326_Q	329_D	0.525	0.99
142_C	195_P	0.525	0.99
597_A	600_P	0.524	0.99
67_A	70_G	0.523	0.99
423_V	442_V	0.521	0.99
194_N	198_T	0.521	0.99
311_T	521_N	0.521	0.99
348_E	352_I	0.520	0.99
111_E	119_D	0.519	0.99
130_D	142_C	0.519	0.99
325_A	442_V	0.518	0.99
290_T	544_E	0.518	0.99
309_T	519_G	0.518	0.99
612_S	617_I	0.517	0.99
470_I	515_M	0.516	0.99
152_S	163_A	0.515	0.99
610_L	616_A	0.514	0.99
176_V	182_I	0.514	0.99
76_V	80_N	0.513	0.99
328_V	435_E	0.512	0.99
554_N	557_K	0.511	0.99
47_T	54_A	0.510	0.99
104_A	123_A	0.510	0.99
297_A	531_V	0.510	0.99
578_F	582_N	0.509	0.99
607_I	620_A	0.509	0.99
196_G	201_D	0.508	0.99
53_M	73_W	0.507	0.99
65_S	68_I	0.507	0.99
140_I	189_I	0.507	0.99
337_A	356_A	0.507	0.99
615_S	622_I	0.507	0.99
157_A	520_T	0.507	0.99
306_L	457_F	0.505	0.99
207_V	210_A	0.505	0.99
531_V	548_M	0.505	0.99
232_F	235_A	0.503	0.99
105_F	112_P	0.503	0.99
46_T	54_A	0.502	0.99
274_I	572_R	0.502	0.99
589_A	595_F	0.501	0.99
472_G	521_N	0.501	0.99
150_G	374_F	0.500	0.99
304_L	457_F	0.500	0.99
339_L	371_H	0.500	0.99

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2zxeA	1	0.9912	100	0.162	Contact Map
3ar4A	1	0.9912	100	0.164	Contact Map
3ixzA	1	0.9912	100	0.165	Contact Map
1mhsA	2	0.9633	100	0.191	Contact Map
3b8cA	1	0.9619	100	0.202	Contact Map
4bbjA	1	0.8856	100	0.28	Contact Map
3j09A	2	0.8842	100	0.307	Contact Map
4umwA	1	0.8358	100	0.316	Contact Map
3j08A	2	0.8812	100	0.316	Contact Map
3skxA	1	0.3827	100	0.744	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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