UVRD - ECOLI - GREMLIN Contacts

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UVRD - DNA helicase II

UniProt:	P03018	Sequences: MDVSYLLDSLNDKQREAVAAPRSNLLVLAGAGSGKTRVLVHRIAWLMSVENCSPYSIMAVTFTNKAAAEMRHRIGQLMGTSQGGMWVGTFHGLAHRLLRAHHMDANLPQDFQILDSEDQLRLLKRLIKAMNLDEKQWPPRQAMWYINSQKDEGLRPHHIQSYGNPVEQTWQKVYQAYQEACDRAGLVDFAELLLRAHELWLNKPHILQHYRERFTNILVDEFQDTNNIQYAWIRLLAGDTGKVMIVGDDDQSIYGWRGAQVENIQRFLNDFPGAETIRLEQNYRSTSNILSAANALIENNNGRLGKKLWTDGADGEPISLYCAFNELDEARFVVNRIKTWQDNGGALAECAILYRSNAQSRVLEEALLQASMPYRIYGGMRFFERQEIKDALSYLRLIANRNDDAAFERVVNTPTRGIGDRTLDVVRQTSRDRQLTLWQACRELLQEKALAGRAASALQRFMELIDALAQETADMPLHVQTDRVIKDSGLRTMYEQEKGEKGQTRIENLEELVTATRQFSYNEEDEDLMPLQAFLSHAALEAGEGQADTWQDAVQLMTLHSAKGLEFPQVFIVGMEEGMFPSQMSLDEGGRLEEERRLAYVGVTRAMQKLTLTYAETRRLYGKEVYHRPSRFIGELPEECVEEVRLRATVSRPVSHQRMGTPMVENDSGYKLGQRVRHAKFGEGTIVNMEGSGEHSRLQVAFQGQGIKWLVAAYARLESV	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG11064
Length:	720 (620)
Sequences:	10727 (7871)
Seq/√Len:	316.1

ECOLI - UVRD REP RECB
BACSU - PCRA YJCD ADDA ADDB
HALSA - Q9HMB4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
56_S	215_T	4.962	1.00
559_L	602_G	4.274	1.00
372_M	554_V	3.926	1.00
15_R	19_A	3.890	1.00
336_R	339_T	3.864	1.00
201_L	231_A	3.766	1.00
333_V	573_V	3.623	1.00
568_P	608_Q	3.481	1.00
575_M	612_L	3.438	1.00
336_R	571_F	3.374	1.00
16_E	275_E	3.311	1.00
11_N	283_Y	3.290	1.00
341_Q	347_L	3.282	1.00
10_L	18_V	3.239	1.00
568_P	607_M	3.206	1.00
569_Q	609_K	3.175	1.00
349_E	568_P	3.067	1.00
577_E	631_R	2.878	1.00
176_A	179_E	2.839	1.00
348_A	552_D	2.795	1.00
346_A	552_D	2.716	1.00
572_I	602_G	2.693	1.00
287_S	291_S	2.678	1.00
195_R	198_E	2.672	1.00
230_Y	270_D	2.625	1.00
557_M	567_F	2.611	1.00
338_K	370_A	2.600	1.00
467_A	487_D	2.583	1.00
355_R	595_E	2.582	1.00
198_E	202_N	2.576	1.00
13_K	16_E	2.487	1.00
86_W	214_F	2.412	1.00
20_A	25_L	2.412	1.00
180_A	183_R	2.390	1.00
337_I	350_C	2.347	1.00
354_Y	556_L	2.297	1.00
571_F	611_T	2.275	1.00
347_L	373_P	2.270	1.00
403_D	406_A	2.259	1.00
336_R	611_T	2.250	1.00
234_R	270_D	2.244	1.00
94_A	196_A	2.199	1.00
569_Q	611_T	2.197	1.00
53_S	56_S	2.171	1.00
334_V	370_A	2.147	1.00
483_R	487_D	2.080	1.00
126_L	180_A	2.054	1.00
345_G	569_Q	2.042	1.00
129_A	176_A	2.041	1.00
387_E	508_N	2.038	1.00
193_L	228_I	2.028	1.00
180_A	184_A	2.017	1.00
481_T	516_T	2.017	1.00
69_E	73_R	2.016	1.00
176_A	180_A	2.011	1.00
396_R	536_S	1.996	1.00
335_N	370_A	1.988	1.00
41_H	77_L	1.962	1.00
37_R	41_H	1.960	1.00
489_G	492_T	1.932	1.00
603_V	610_L	1.923	1.00
407_F	411_V	1.923	1.00
262_E	266_R	1.923	1.00
566_E	607_M	1.915	1.00
201_L	235_L	1.915	1.00
331_R	366_A	1.905	1.00
179_E	183_R	1.898	1.00
354_Y	360_S	1.898	1.00
207_L	211_R	1.888	1.00
204_P	207_L	1.886	1.00
340_W	569_Q	1.850	1.00
88_G	93_L	1.849	1.00
341_Q	350_C	1.849	1.00
25_L	277_I	1.847	1.00
329_E	613_T	1.846	1.00
227_N	260_Q	1.844	1.00
147_N	190_A	1.840	1.00
43_I	59_A	1.818	1.00
101_H	209_H	1.816	1.00
331_R	370_A	1.814	1.00
114_L	186_L	1.810	1.00
363_L	573_V	1.807	1.00
471_E	483_R	1.782	1.00
282_N	285_S	1.778	1.00
129_A	180_A	1.777	1.00
332_F	613_T	1.773	1.00
537_H	540_L	1.752	1.00
346_A	349_E	1.736	1.00
366_A	369_Q	1.731	1.00
340_W	350_C	1.719	1.00
181_C	191_E	1.706	1.00
323_A	332_F	1.706	1.00
340_W	571_F	1.697	1.00
46_L	216_N	1.695	1.00
187_V	195_R	1.690	1.00
104_D	206_I	1.688	1.00
108_P	185_G	1.686	1.00
408_E	427_R	1.668	1.00
366_A	370_A	1.661	1.00
312_G	608_Q	1.652	1.00
27_V	244_M	1.638	1.00
72_H	76_Q	1.630	1.00
559_L	580_F	1.629	1.00
320_L	614_Y	1.624	1.00
155_R	158_H	1.622	1.00
442_R	466_D	1.621	1.00
97_L	196_A	1.614	1.00
200_W	207_L	1.612	1.00
322_C	614_Y	1.610	1.00
231_A	234_R	1.609	1.00
91_H	192_L	1.600	1.00
491_R	506_I	1.576	1.00
197_H	231_A	1.568	1.00
476_P	479_V	1.567	1.00
339_T	343_N	1.566	1.00
19_A	45_W	1.565	1.00
160_Q	175_Q	1.554	1.00
45_W	49_V	1.548	1.00
126_L	130_M	1.546	1.00
208_Q	211_R	1.542	1.00
102_H	187_V	1.541	1.00
250_D	303_R	1.537	1.00
492_T	495_E	1.532	1.00
490_L	494_Y	1.527	1.00
58_M	217_I	1.518	1.00
13_K	281_Q	1.517	1.00
345_G	608_Q	1.508	1.00
44_A	77_L	1.507	1.00
292_A	318_I	1.495	1.00
575_M	599_A	1.491	1.00
101_H	210_Y	1.491	1.00
208_Q	212_E	1.489	1.00
219_V	233_I	1.488	1.00
266_R	270_D	1.485	1.00
352_I	367_L	1.484	1.00
266_R	269_N	1.479	1.00
491_R	510_E	1.473	1.00
281_Q	309_W	1.469	1.00
333_V	571_F	1.465	1.00
25_L	244_M	1.463	1.00
341_Q	346_A	1.462	1.00
178_Q	181_C	1.453	1.00
296_L	603_V	1.442	1.00
217_I	237_A	1.441	1.00
222_F	230_Y	1.438	1.00
596_R	635_E	1.437	1.00
241_G	273_G	1.435	1.00
340_W	611_T	1.434	1.00
200_W	235_L	1.433	1.00
572_I	612_L	1.432	1.00
23_S	275_E	1.431	1.00
424_D	428_Q	1.425	1.00
367_L	556_L	1.425	1.00
40_V	74_I	1.420	1.00
387_E	505_R	1.419	1.00
397_L	410_V	1.418	1.00
47_M	78_M	1.410	1.00
175_Q	179_E	1.409	1.00
527_D	530_P	1.409	1.00
316_E	609_K	1.408	1.00
351_A	567_F	1.407	1.00
419_G	422_T	1.396	1.00
482_D	513_V	1.389	1.00
333_V	363_L	1.388	1.00
359_Q	574_G	1.385	1.00
338_K	342_D	1.382	1.00
178_Q	182_D	1.379	1.00
336_R	340_W	1.378	1.00
531_L	534_F	1.369	1.00
478_H	520_S	1.369	1.00
187_V	192_L	1.369	1.00
319_S	609_K	1.366	1.00
43_I	74_I	1.364	1.00
177_Y	188_D	1.361	1.00
197_H	232_W	1.361	1.00
122_L	180_A	1.355	1.00
12_D	15_R	1.350	1.00
360_S	556_L	1.347	1.00
340_W	609_K	1.345	1.00
267_F	274_A	1.341	1.00
199_L	206_I	1.336	1.00
125_R	180_A	1.335	1.00
268_L	276_T	1.335	1.00
471_E	475_M	1.331	1.00
475_M	479_V	1.329	1.00
123_L	173_V	1.328	1.00
519_F	530_P	1.327	1.00
295_A	637_P	1.326	1.00
97_L	200_W	1.325	1.00
107_L	195_R	1.321	1.00
93_L	97_L	1.317	1.00
287_S	313_A	1.312	1.00
319_S	336_R	1.308	1.00
204_P	208_Q	1.306	1.00
58_M	214_F	1.305	1.00
354_Y	573_V	1.303	1.00
340_W	345_G	1.302	1.00
299_N	635_E	1.302	1.00
337_I	554_V	1.299	1.00
97_L	210_Y	1.299	1.00
355_R	598_L	1.296	1.00
337_I	571_F	1.285	1.00
421_R	425_V	1.277	1.00
126_L	176_A	1.277	1.00
439_Q	443_E	1.273	1.00
12_D	16_E	1.272	1.00
468_L	487_D	1.265	1.00
105_A	199_L	1.265	1.00
281_Q	311_D	1.262	1.00
323_A	613_T	1.260	1.00
393_S	409_R	1.259	1.00
289_I	293_A	1.253	1.00
130_M	176_A	1.250	1.00
391_A	509_L	1.247	1.00
31_A	294_N	1.247	1.00
459_Q	463_E	1.247	1.00
347_L	350_C	1.246	1.00
203_K	206_I	1.246	1.00
334_V	366_A	1.244	1.00
252_S	255_G	1.239	1.00
375_R	553_A	1.239	1.00
451_A	454_A	1.238	1.00
42_R	244_M	1.236	1.00
352_I	363_L	1.233	1.00
197_H	235_L	1.232	1.00
207_L	235_L	1.232	1.00
86_W	96_R	1.230	1.00
534_F	537_H	1.229	1.00
292_A	603_V	1.224	1.00
339_T	342_D	1.217	1.00
345_G	350_C	1.216	1.00
391_A	481_T	1.214	1.00
599_A	603_V	1.212	1.00
94_A	232_W	1.210	1.00
13_K	280_E	1.210	1.00
390_D	409_R	1.208	1.00
74_I	87_V	1.203	1.00
491_R	495_E	1.202	1.00
82_Q	85_M	1.190	1.00
227_N	231_A	1.190	1.00
453_R	457_A	1.185	1.00
569_Q	608_Q	1.183	1.00
216_N	242_K	1.181	1.00
46_L	52_C	1.180	1.00
629_P	633_I	1.180	1.00
119_Q	177_Y	1.176	1.00
28_L	249_D	1.174	1.00
367_L	374_Y	1.172	1.00
528_L	531_L	1.162	1.00
95_H	99_R	1.157	1.00
23_S	242_K	1.147	1.00
88_G	92_G	1.147	1.00
395_L	481_T	1.146	1.00
350_C	569_Q	1.143	1.00
96_R	100_A	1.142	1.00
338_K	347_L	1.141	1.00
126_L	173_V	1.138	1.00
98_L	196_A	1.137	1.00
329_E	574_G	1.135	1.00
16_E	19_A	1.134	1.00
394_Y	484_V	1.132	1.00
197_H	201_L	1.132	1.00
102_H	105_A	1.130	1.00
407_F	441_C	1.127	1.00
45_W	50_E	1.126	1.00
39_L	218_L	1.125	1.00
211_R	239_D	1.120	1.00
26_L	245_I	1.115	1.00
337_I	347_L	1.115	1.00
394_Y	410_V	1.114	1.00
345_G	568_P	1.111	1.00
497_E	502_G	1.110	1.00
252_S	259_A	1.107	1.00
400_N	403_D	1.104	1.00
157_H	175_Q	1.103	1.00
452_G	455_A	1.098	1.00
588_E	591_R	1.097	1.00
429_T	433_R	1.093	1.00
557_M	562_A	1.092	1.00
534_F	540_L	1.089	1.00
254_Y	257_R	1.088	1.00
123_L	143_M	1.087	1.00
153_G	228_I	1.086	1.00
158_H	161_S	1.085	1.00
169_T	172_K	1.082	1.00
68_A	72_H	1.081	1.00
347_L	372_M	1.067	1.00
20_A	275_E	1.067	1.00
462_M	466_D	1.065	1.00
464_L	468_L	1.065	1.00
402_N	436_T	1.064	1.00
322_C	616_E	1.059	1.00
104_D	203_K	1.058	1.00
210_Y	214_F	1.056	1.00
571_F	613_T	1.054	1.00
401_R	469_A	1.051	1.00
107_L	187_V	1.048	1.00
196_A	232_W	1.043	1.00
340_W	343_N	1.042	1.00
91_H	193_L	1.040	1.00
21_P	46_L	1.039	1.00
475_M	483_R	1.038	1.00
396_R	406_A	1.036	1.00
43_I	57_I	1.036	1.00
293_A	604_T	1.036	1.00
172_K	175_Q	1.033	1.00
361_R	365_E	1.031	1.00
20_A	23_S	1.027	1.00
356_S	359_Q	1.026	1.00
26_L	276_T	1.025	1.00
375_R	555_Q	1.019	1.00
332_F	336_R	1.015	1.00
104_D	205_H	1.012	1.00
324_F	616_E	1.011	1.00
350_C	571_F	1.006	1.00
288_N	291_S	1.006	1.00
412_N	416_R	1.005	1.00
330_A	334_V	1.005	1.00
478_H	517_R	1.003	1.00
100_A	213_R	1.002	1.00
166_V	170_W	1.001	1.00
397_L	407_F	0.998	1.00
21_P	50_E	0.996	1.00
125_R	129_A	0.996	1.00
55_Y	84_G	0.992	1.00
516_T	531_L	0.991	1.00
297_I	300_N	0.990	1.00
512_L	516_T	0.988	1.00
148_S	152_E	0.987	1.00
435_L	443_E	0.983	1.00
331_R	335_N	0.981	1.00
482_D	486_K	0.971	1.00
154_L	159_I	0.967	1.00
151_D	190_A	0.964	1.00
338_K	341_Q	0.964	1.00
461_F	465_I	0.962	1.00
402_N	439_Q	0.962	1.00
182_D	195_R	0.957	1.00
582_S	585_S	0.950	1.00
398_I	484_V	0.950	1.00
221_E	563_K	0.949	1.00
112_Q	118_D	0.949	1.00
93_L	210_Y	0.949	1.00
149_Q	159_I	0.948	1.00
65_K	69_E	0.946	1.00
123_L	127_I	0.946	1.00
255_G	590_G	0.945	1.00
398_I	480_Q	0.944	1.00
150_K	191_E	0.943	1.00
286_T	608_Q	0.943	1.00
325_N	328_D	0.942	1.00
365_E	369_Q	0.942	1.00
442_R	462_M	0.940	1.00
464_L	467_A	0.936	1.00
91_H	190_A	0.935	1.00
97_L	199_L	0.934	1.00
435_L	440_A	0.932	1.00
603_V	612_L	0.930	1.00
225_T	263_N	0.927	1.00
410_V	461_F	0.925	1.00
42_R	242_K	0.923	1.00
222_F	225_T	0.922	1.00
573_V	613_T	0.918	1.00
127_I	132_L	0.917	1.00
119_Q	143_M	0.913	1.00
196_A	200_W	0.909	1.00
531_L	537_H	0.908	1.00
357_N	360_S	0.907	1.00
222_F	245_I	0.907	1.00
364_E	374_Y	0.905	1.00
172_K	176_A	0.904	1.00
391_A	512_L	0.904	1.00
321_Y	332_F	0.899	1.00
134_E	137_W	0.899	1.00
10_L	37_R	0.899	1.00
116_S	119_Q	0.896	1.00
60_V	233_I	0.894	1.00
123_L	146_I	0.893	1.00
60_V	93_L	0.892	1.00
288_N	318_I	0.892	1.00
333_V	613_T	0.891	1.00
529_M	533_A	0.888	1.00
334_V	338_K	0.887	1.00
438_W	442_R	0.887	1.00
420_D	424_D	0.885	1.00
101_H	104_D	0.882	1.00
330_A	363_L	0.882	1.00
463_E	467_A	0.882	1.00
426_V	437_L	0.881	1.00
454_A	457_A	0.881	1.00
389_K	393_S	0.881	1.00
52_C	56_S	0.880	1.00
324_F	328_D	0.877	1.00
532_Q	537_H	0.876	1.00
261_V	264_I	0.874	1.00
536_S	540_L	0.873	1.00
377_Y	561_S	0.873	1.00
233_I	243_V	0.873	1.00
396_R	403_D	0.870	1.00
264_I	267_F	0.869	1.00
61_T	66_A	0.866	1.00
388_I	512_L	0.866	1.00
47_M	85_M	0.864	1.00
460_R	463_E	0.863	1.00
548_D	551_Q	0.859	1.00
467_A	483_R	0.859	1.00
91_H	98_L	0.858	1.00
21_P	216_N	0.855	1.00
391_A	485_I	0.853	1.00
193_L	197_H	0.853	1.00
576_E	615_A	0.852	1.00
348_A	553_A	0.852	1.00
316_E	319_S	0.851	1.00
455_A	459_Q	0.849	1.00
103_M	109_Q	0.849	1.00
21_P	45_W	0.847	1.00
364_E	368_L	0.846	1.00
334_V	367_L	0.845	1.00
555_Q	567_F	0.843	1.00
290_L	308_L	0.841	1.00
290_L	293_A	0.841	1.00
466_D	469_A	0.841	1.00
335_N	339_T	0.840	1.00
559_L	572_I	0.839	1.00
154_L	158_H	0.837	1.00
163_G	171_Q	0.836	1.00
68_A	71_R	0.836	1.00
148_S	151_D	0.835	1.00
193_L	232_W	0.834	1.00
422_T	425_V	0.834	1.00
296_L	599_A	0.830	1.00
288_N	314_D	0.828	1.00
263_N	267_F	0.828	1.00
17_A	27_V	0.827	1.00
480_Q	484_V	0.826	1.00
492_T	496_Q	0.826	1.00
363_L	556_L	0.826	1.00
336_R	609_K	0.822	1.00
535_L	539_A	0.822	1.00
575_M	580_F	0.819	1.00
398_I	468_L	0.818	1.00
268_L	304_L	0.818	1.00
160_Q	171_Q	0.817	1.00
511_E	514_T	0.815	1.00
467_A	471_E	0.814	1.00
149_Q	170_W	0.812	1.00
250_D	297_I	0.810	1.00
331_R	369_Q	0.810	1.00
390_D	490_L	0.809	1.00
42_R	216_N	0.803	1.00
381_R	384_E	0.803	1.00
433_R	443_E	0.801	1.00
31_A	600_Y	0.800	1.00
24_N	241_G	0.799	1.00
468_L	480_Q	0.798	1.00
364_E	556_L	0.798	1.00
443_E	446_Q	0.794	1.00
249_D	306_K	0.794	1.00
509_L	513_V	0.793	1.00
145_Y	149_Q	0.793	1.00
581_P	595_E	0.792	1.00
453_R	456_S	0.791	1.00
422_T	457_A	0.789	1.00
429_T	440_A	0.787	1.00
13_K	309_W	0.786	1.00
486_K	491_R	0.784	1.00
22_R	216_N	0.784	1.00
95_H	192_L	0.783	1.00
70_M	73_R	0.782	1.00
194_L	228_I	0.782	1.00
157_H	161_S	0.782	1.00
75_G	83_G	0.780	1.00
330_A	362_V	0.780	1.00
30_G	33_S	0.780	1.00
116_S	143_M	0.780	1.00
174_Y	178_Q	0.780	1.00
218_L	244_M	0.779	1.00
478_H	482_D	0.778	1.00
495_E	506_I	0.777	1.00
399_A	532_Q	0.777	1.00
197_H	228_I	0.776	1.00
334_V	372_M	0.776	1.00
31_A	250_D	0.775	1.00
374_Y	556_L	0.775	1.00
587_D	591_R	0.774	1.00
295_A	298_E	0.774	1.00
337_I	367_L	0.774	1.00
133_D	176_A	0.772	1.00
306_K	310_T	0.772	1.00
537_H	542_A	0.770	0.99
120_L	140_R	0.769	0.99
362_V	366_A	0.768	0.99
287_S	314_D	0.768	0.99
436_T	439_Q	0.765	0.99
347_L	554_V	0.765	0.99
506_I	510_E	0.765	0.99
234_R	271_F	0.765	0.99
231_A	235_L	0.764	0.99
395_L	399_A	0.764	0.99
475_M	480_Q	0.763	0.99
146_I	174_Y	0.761	0.99
326_E	362_V	0.760	0.99
291_S	295_A	0.760	0.99
572_I	599_A	0.759	0.99
156_P	174_Y	0.758	0.99
255_G	587_D	0.758	0.99
100_A	209_H	0.758	0.99
153_G	194_L	0.757	0.99
267_F	271_F	0.756	0.99
286_T	289_I	0.754	0.99
91_H	226_N	0.754	0.99
24_N	242_K	0.753	0.99
418_I	422_T	0.751	0.99
429_T	443_E	0.749	0.99
293_A	603_V	0.746	0.99
382_F	388_I	0.746	0.99
212_E	239_D	0.745	0.99
456_S	460_R	0.745	0.99
252_S	256_W	0.744	0.99
142_A	170_W	0.743	0.99
562_A	567_F	0.742	0.99
300_N	596_R	0.741	0.99
130_M	172_K	0.741	0.99
481_T	513_V	0.740	0.99
60_V	64_N	0.740	0.99
217_I	236_L	0.739	0.99
601_V	605_R	0.738	0.99
98_L	199_L	0.737	0.99
168_Q	172_K	0.737	0.99
483_R	486_K	0.736	0.99
154_L	162_Y	0.734	0.99
532_Q	536_S	0.731	0.99
45_W	48_S	0.730	0.99
86_W	213_R	0.729	0.99
443_E	447_E	0.727	0.99
592_L	631_R	0.727	0.99
428_Q	432_D	0.725	0.99
224_D	563_K	0.725	0.99
519_F	526_E	0.724	0.99
27_V	277_I	0.723	0.99
347_L	552_D	0.721	0.99
264_I	268_L	0.721	0.99
147_N	151_D	0.718	0.99
531_L	540_L	0.718	0.99
390_D	393_S	0.717	0.99
17_A	244_M	0.716	0.99
44_A	48_S	0.716	0.99
531_L	535_L	0.716	0.99
477_L	480_Q	0.714	0.99
392_L	396_R	0.713	0.99
237_A	243_V	0.712	0.99
455_A	462_M	0.712	0.99
532_Q	540_L	0.711	0.99
328_D	331_R	0.710	0.99
534_F	538_A	0.709	0.99
332_F	611_T	0.709	0.99
221_E	224_D	0.709	0.99
385_R	388_I	0.708	0.99
460_R	464_L	0.706	0.99
262_E	590_G	0.706	0.99
144_W	148_S	0.706	0.99
178_Q	195_R	0.705	0.99
215_T	240_T	0.703	0.99
179_E	182_D	0.703	0.99
59_A	70_M	0.703	0.99
114_L	181_C	0.702	0.99
234_R	238_G	0.702	0.99
247_G	251_Q	0.700	0.99
37_R	40_V	0.700	0.99
518_Q	522_N	0.699	0.99
536_S	542_A	0.698	0.99
478_H	513_V	0.698	0.99
572_I	575_M	0.698	0.99
345_G	349_E	0.697	0.99
527_D	531_L	0.697	0.99
413_T	493_M	0.696	0.99
105_A	203_K	0.696	0.99
47_M	52_C	0.696	0.99
219_V	245_I	0.694	0.99
293_A	296_L	0.693	0.99
466_D	470_Q	0.692	0.99
90_F	225_T	0.692	0.99
88_G	96_R	0.688	0.99
71_R	75_G	0.687	0.99
468_L	484_V	0.686	0.99
113_I	192_L	0.684	0.99
102_H	107_L	0.683	0.99
280_E	307_K	0.683	0.99
600_Y	604_T	0.683	0.99
421_R	424_D	0.683	0.99
91_H	187_V	0.682	0.99
330_A	366_A	0.682	0.99
77_L	80_T	0.681	0.99
285_S	290_L	0.680	0.99
67_A	70_M	0.680	0.99
457_A	460_R	0.680	0.99
382_F	508_N	0.679	0.99
209_H	213_R	0.678	0.99
341_Q	345_G	0.678	0.99
412_N	420_D	0.678	0.99
422_T	458_L	0.676	0.99
287_S	310_T	0.675	0.99
390_D	414_P	0.674	0.99
290_L	294_N	0.673	0.99
535_L	542_A	0.673	0.99
56_S	213_R	0.672	0.99
41_H	44_A	0.671	0.99
464_L	487_D	0.671	0.99
191_E	195_R	0.671	0.99
27_V	38_V	0.669	0.99
157_H	160_Q	0.669	0.99
200_W	210_Y	0.668	0.99
456_S	459_Q	0.665	0.99
41_H	45_W	0.665	0.99
95_H	113_I	0.664	0.98
285_S	289_I	0.664	0.98
334_V	554_V	0.664	0.98
46_L	57_I	0.663	0.98
514_T	518_Q	0.663	0.98
249_D	278_R	0.660	0.98
438_W	466_D	0.660	0.98
251_Q	601_V	0.660	0.98
149_Q	154_L	0.658	0.98
452_G	456_S	0.657	0.98
75_G	82_Q	0.655	0.98
515_A	534_F	0.654	0.98
319_S	611_T	0.654	0.98
288_N	317_P	0.653	0.98
43_I	85_M	0.649	0.98
629_P	634_G	0.648	0.98
572_I	603_V	0.648	0.98
16_E	277_I	0.647	0.98
476_P	520_S	0.647	0.98
438_W	462_M	0.645	0.98
293_A	297_I	0.644	0.98
291_S	314_D	0.644	0.98
64_N	91_H	0.643	0.98
386_Q	390_D	0.642	0.98
142_A	173_V	0.641	0.98
347_L	568_P	0.641	0.98
514_T	517_R	0.640	0.98
125_R	184_A	0.638	0.98
22_R	50_E	0.638	0.98
159_I	163_G	0.638	0.98
225_T	229_Q	0.637	0.98
485_I	491_R	0.635	0.98
166_V	169_T	0.635	0.98
260_Q	263_N	0.634	0.98
208_Q	239_D	0.632	0.98
441_C	462_M	0.631	0.98
447_E	450_L	0.630	0.98
576_E	618_R	0.630	0.98
227_N	266_R	0.630	0.98
79_G	82_Q	0.630	0.98
235_L	238_G	0.629	0.98
20_A	24_N	0.629	0.98
601_V	604_T	0.629	0.98
503_Q	507_E	0.628	0.98
212_E	240_T	0.628	0.98
528_L	537_H	0.628	0.98
222_F	264_I	0.627	0.98
133_D	136_Q	0.627	0.98
341_Q	552_D	0.626	0.98
450_L	454_A	0.626	0.98
91_H	560_H	0.626	0.98
26_L	264_I	0.626	0.98
593_E	596_R	0.626	0.98
538_A	542_A	0.626	0.98
386_Q	413_T	0.625	0.98
578_G	581_P	0.624	0.98
281_Q	310_T	0.623	0.98
225_T	259_A	0.623	0.98
259_A	263_N	0.622	0.98
468_L	472_T	0.622	0.98
62_F	221_E	0.622	0.98
439_Q	442_R	0.622	0.98
131_N	134_E	0.621	0.98
292_A	296_L	0.620	0.98
518_Q	521_Y	0.620	0.98
47_M	54_P	0.620	0.98
367_L	554_V	0.620	0.98
269_N	303_R	0.619	0.98
354_Y	363_L	0.618	0.98
364_E	376_I	0.617	0.98
505_R	508_N	0.616	0.98
40_V	70_M	0.616	0.98
214_F	217_I	0.616	0.98
42_R	218_L	0.616	0.98
105_A	195_R	0.616	0.98
174_Y	181_C	0.615	0.98
224_D	601_V	0.615	0.98
42_R	46_L	0.614	0.98
612_L	633_I	0.612	0.97
66_A	69_E	0.612	0.97
302_G	593_E	0.612	0.97
81_S	84_G	0.612	0.97
16_E	20_A	0.611	0.97
497_E	500_E	0.610	0.97
563_K	601_V	0.610	0.97
114_L	118_D	0.610	0.97
351_A	557_M	0.608	0.97
341_Q	349_E	0.607	0.97
437_L	440_A	0.607	0.97
307_K	310_T	0.606	0.97
395_L	480_Q	0.606	0.97
515_A	518_Q	0.606	0.97
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468_L	471_E	0.606	0.97
458_L	462_M	0.606	0.97
327_L	362_V	0.605	0.97
127_I	142_A	0.603	0.97
58_M	86_W	0.602	0.97
28_L	264_I	0.602	0.97
300_N	303_R	0.602	0.97
481_T	512_L	0.602	0.97
40_V	77_L	0.601	0.97
177_Y	181_C	0.600	0.97
165_P	168_Q	0.600	0.97
261_V	265_Q	0.599	0.97
181_C	186_L	0.598	0.97
280_E	309_W	0.598	0.97
471_E	474_D	0.598	0.97
245_I	267_F	0.597	0.97
367_L	372_M	0.596	0.97
43_I	218_L	0.596	0.97
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485_I	513_V	0.595	0.97
411_V	418_I	0.595	0.97
384_E	389_K	0.594	0.97
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460_R	487_D	0.594	0.97
18_V	38_V	0.594	0.97
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490_L	493_M	0.593	0.97
61_T	70_M	0.592	0.97
516_T	519_F	0.592	0.97
594_E	597_R	0.592	0.97
345_G	609_K	0.591	0.97
393_S	406_A	0.590	0.97
44_A	78_M	0.590	0.97
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469_A	473_A	0.590	0.97
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392_L	512_L	0.584	0.97
255_G	594_E	0.584	0.97
205_H	208_Q	0.583	0.97
470_Q	474_D	0.582	0.97
517_R	521_Y	0.582	0.97
338_K	372_M	0.580	0.96
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57_I	216_N	0.577	0.96
18_V	21_P	0.577	0.96
632_F	635_E	0.577	0.96
248_D	251_Q	0.577	0.96
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528_L	533_A	0.575	0.96
510_E	514_T	0.575	0.96
353_L	559_L	0.574	0.96
596_R	632_F	0.574	0.96
120_L	143_M	0.573	0.96
140_R	144_W	0.573	0.96
93_L	214_F	0.573	0.96
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392_L	535_L	0.572	0.96
533_A	537_H	0.572	0.96
160_Q	172_K	0.572	0.96
66_A	73_R	0.571	0.96
224_D	251_Q	0.571	0.96
37_R	607_M	0.570	0.96
614_Y	629_P	0.569	0.96
332_F	335_N	0.569	0.96
579_M	627_H	0.569	0.96
63_T	66_A	0.568	0.96
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458_L	461_F	0.567	0.96
223_Q	251_Q	0.567	0.96
194_L	198_E	0.567	0.96
350_C	554_V	0.567	0.96
44_A	74_I	0.566	0.96
15_R	45_W	0.565	0.96
356_S	582_S	0.564	0.96
441_C	458_L	0.562	0.96
362_V	365_E	0.558	0.96
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336_R	613_T	0.558	0.96
159_I	171_Q	0.556	0.96
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265_Q	269_N	0.556	0.96
67_A	88_G	0.555	0.96
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126_L	129_A	0.554	0.95
425_V	428_Q	0.554	0.95
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58_M	236_L	0.552	0.95
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397_L	465_I	0.551	0.95
513_V	516_T	0.550	0.95
265_Q	268_L	0.550	0.95
221_E	601_V	0.549	0.95
537_H	541_E	0.549	0.95
507_E	510_E	0.548	0.95
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468_L	488_S	0.546	0.95
117_E	120_L	0.546	0.95
243_V	267_F	0.545	0.95
444_L	448_K	0.545	0.95
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224_D	564_G	0.543	0.95
98_L	105_A	0.542	0.95
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141_Q	144_W	0.537	0.95
398_I	472_T	0.537	0.95
462_M	465_I	0.536	0.95
192_L	196_A	0.536	0.95
196_A	199_L	0.536	0.95
528_L	534_F	0.536	0.95
530_P	533_A	0.535	0.95
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564_G	601_V	0.534	0.94
244_M	256_W	0.533	0.94
36_T	73_R	0.533	0.94
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578_G	583_Q	0.532	0.94
63_T	70_M	0.532	0.94
526_E	530_P	0.532	0.94
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300_N	635_E	0.531	0.94
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320_L	633_I	0.528	0.94
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295_A	636_L	0.526	0.94
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189_F	193_L	0.525	0.94
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560_H	563_K	0.522	0.94
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153_G	231_A	0.522	0.94
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101_H	206_I	0.520	0.94
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115_D	118_D	0.517	0.94
631_R	635_E	0.517	0.94
341_Q	554_V	0.516	0.93
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122_L	126_L	0.516	0.93
471_E	487_D	0.515	0.93
587_D	590_G	0.515	0.93
155_R	161_S	0.514	0.93
211_R	240_T	0.514	0.93
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493_M	496_Q	0.513	0.93
74_I	85_M	0.513	0.93
564_G	605_R	0.513	0.93
567_F	570_V	0.512	0.93
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114_L	119_Q	0.512	0.93
615_A	618_R	0.512	0.93
247_G	264_I	0.511	0.93
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28_L	276_T	0.509	0.93
394_Y	414_P	0.509	0.93
454_A	468_L	0.509	0.93
383_F	387_E	0.509	0.93
535_L	538_A	0.509	0.93
64_N	95_H	0.508	0.93
122_L	184_A	0.508	0.93
248_D	563_K	0.507	0.93
164_N	168_Q	0.506	0.93
48_S	51_N	0.505	0.93
48_S	81_S	0.505	0.93
181_C	188_D	0.505	0.93
416_R	464_L	0.505	0.93
461_F	469_A	0.505	0.93
205_H	209_H	0.504	0.93
61_T	69_E	0.504	0.93
47_M	57_I	0.503	0.93
580_F	599_A	0.502	0.92
328_D	332_F	0.502	0.92
330_A	333_V	0.502	0.92
526_E	529_M	0.502	0.92
330_A	574_G	0.501	0.92
91_H	188_D	0.501	0.92
364_E	378_G	0.500	0.92
298_E	307_K	0.500	0.92
141_Q	145_Y	0.500	0.92
504_T	507_E	0.500	0.92
11_N	290_L	0.500	0.92

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4c2tA	1	0.8903	100	0.096	Contact Map
1pjrA	1	0.8611	100	0.097	Contact Map
3lfuA	1	0.8792	100	0.225	Contact Map
1uaaA	2	0.875	100	0.231	Contact Map
4c2uA	1	0.8972	100	0.242	Contact Map
3u4qA	1	0.9264	100	0.242	Contact Map
1w36B	1	0.9361	100	0.312	Contact Map
3u4qB	1	0.9028	100	0.391	Contact Map
4pj3A	1	0.6958	100	0.576	Contact Map
2xzlA	1	0.5667	100	0.65	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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