DNAA - ECOLI - GREMLIN Contacts

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DNAA - Chromosomal replication initiator protein DnaA

UniProt:	P03004	Sequences: MSLSLWQQCLARLQDELPATEFSMWIRPLQAELSDNTLALYAPNRFVLDWVRDKYLNNINGLLTSFCGADAPQLRFEVGTKPVTQTPQAAVTSNVAAPAQVAQTQPQRAAPSTRSGWDNVPAPAEPTYRSNVNVKHTFDNFVEGKSNQLARAAARQVADNPGGAYNPLFLYGGTGLGKTHLLHAVGNGIMARKPNAKVVYMHSERFVQDMVKALQNNAIEEFKRYYRSVDALLIDDIQFFANKERSQEEFFHTFNALLEGNQQIILTSDRYPKEINGVEDRLKSRFGWGLTVAIEPPELETRVAILMKKADENDIRLPGEVAFFIAKRLRSNVRELEGALNRVIANANFTGRAITIDFVREALRDLLALQEKLVTIDNIQKTVAEYYKIKVADLLSKRRSRSVARPRQMAMALAKELTNHSLPEIGDAFGGRDHTTVLHACRKIEQLREESHDIKEDFSNLIRTLSS	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10235
Length:	467 (439)
Sequences:	2986 (1854)
Seq/√Len:	88.5

ECOLI - DNAA
BACSU - DNAA

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
411_M	437_V	4.031	1.00
188_G	191_A	3.587	1.00
185_V	265_I	3.490	1.00
153_A	290_L	3.234	1.00
307_M	319_G	3.202	1.00
189_I	231_A	3.199	1.00
376_I	380_Q	3.117	1.00
448_R	458_F	3.005	1.00
227_R	253_T	2.857	1.00
193_K	196_A	2.855	1.00
321_V	359_V	2.837	1.00
387_Y	457_D	2.825	1.00
426_G	431_G	2.715	1.00
416_E	462_I	2.662	1.00
448_R	455_K	2.656	1.00
48_L	52_R	2.606	1.00
455_K	459_S	2.563	1.00
441_C	445_E	2.544	1.00
258_L	288_W	2.527	1.00
218_A	221_E	2.525	1.00
435_T	438_L	2.433	1.00
376_I	414_A	2.411	1.00
157_V	168_L	2.408	1.00
410_A	429_F	2.365	1.00
50_W	54_K	2.363	1.00
380_Q	395_L	2.358	1.00
23_S	27_R	2.355	1.00
145_K	148_Q	2.343	1.00
209_D	226_Y	2.310	1.00
426_G	430_G	2.250	1.00
199_V	229_V	2.248	1.00
273_K	287_G	2.236	1.00
62_L	66_F	2.190	1.00
29_L	40_L	2.189	1.00
209_D	225_Y	2.147	1.00
12_R	65_S	2.133	1.00
151_R	155_R	2.131	1.00
16_E	58_N	2.128	1.00
250_F	266_L	2.127	1.00
426_G	432_R	2.120	1.00
204_E	227_R	2.110	1.00
143_E	151_R	2.109	1.00
444_I	454_I	2.094	1.00
387_Y	409_M	2.079	1.00
380_Q	429_F	2.074	1.00
309_K	337_E	2.059	1.00
448_R	454_I	2.053	1.00
19_A	23_S	2.051	1.00
284_S	332_N	2.047	1.00
324_F	367_L	2.046	1.00
207_V	246_S	2.033	1.00
390_K	393_D	2.014	1.00
210_M	245_R	1.974	1.00
299_L	303_V	1.971	1.00
384_A	391_V	1.959	1.00
416_E	445_E	1.959	1.00
38_L	63_L	1.958	1.00
447_L	451_S	1.952	1.00
306_L	340_L	1.950	1.00
188_G	192_R	1.922	1.00
32_E	39_A	1.917	1.00
376_I	428_A	1.913	1.00
210_M	222_F	1.889	1.00
341_N	348_N	1.856	1.00
386_Y	457_D	1.853	1.00
214_L	219_I	1.808	1.00
204_E	239_F	1.804	1.00
447_L	454_I	1.801	1.00
357_D	360_R	1.797	1.00
153_A	168_L	1.783	1.00
33_L	38_L	1.760	1.00
446_Q	450_E	1.752	1.00
310_A	322_A	1.742	1.00
380_Q	391_V	1.717	1.00
37_T	75_R	1.708	1.00
233_L	267_T	1.701	1.00
429_F	440_A	1.701	1.00
303_V	323_F	1.700	1.00
381_K	385_E	1.697	1.00
233_L	265_I	1.692	1.00
56_L	76_F	1.681	1.00
223_K	249_E	1.678	1.00
303_V	322_A	1.676	1.00
408_Q	439_H	1.674	1.00
408_Q	411_M	1.663	1.00
67_C	71_A	1.663	1.00
29_L	42_A	1.655	1.00
204_E	253_T	1.653	1.00
51_V	76_F	1.643	1.00
237_I	266_L	1.630	1.00
411_M	440_A	1.627	1.00
422_L	441_C	1.622	1.00
158_A	188_G	1.599	1.00
318_P	321_V	1.596	1.00
227_R	249_E	1.578	1.00
132_V	186_G	1.575	1.00
376_I	420_H	1.573	1.00
31_A	41_Y	1.561	1.00
201_M	226_Y	1.546	1.00
36_N	69_A	1.540	1.00
413_L	462_I	1.525	1.00
377_D	428_A	1.523	1.00
462_I	466_S	1.515	1.00
443_K	447_L	1.515	1.00
356_I	360_R	1.512	1.00
142_V	308_K	1.509	1.00
325_I	343_V	1.509	1.00
41_Y	79_G	1.507	1.00
174_T	284_S	1.501	1.00
255_N	259_E	1.499	1.00
332_N	335_E	1.499	1.00
321_V	356_I	1.498	1.00
249_E	253_T	1.495	1.00
150_A	181_L	1.482	1.00
300_E	304_A	1.470	0.99
391_V	395_L	1.464	0.99
412_A	458_F	1.459	0.99
251_F	281_R	1.459	0.99
60_N	70_D	1.458	0.99
386_Y	460_N	1.453	0.99
424_E	427_D	1.448	0.99
306_L	336_L	1.444	0.99
60_N	73_Q	1.439	0.99
307_M	322_A	1.428	0.99
9_C	63_L	1.428	0.99
14_Q	19_A	1.423	0.99
443_K	446_Q	1.421	0.99
11_A	14_Q	1.412	0.99
290_L	345_A	1.411	0.99
58_N	62_L	1.410	0.99
149_L	345_A	1.407	0.99
22_F	26_I	1.404	0.99
393_D	398_R	1.372	0.99
385_E	464_T	1.369	0.99
138_F	184_A	1.366	0.99
189_I	196_A	1.364	0.99
324_F	356_I	1.345	0.99
14_Q	27_R	1.342	0.99
227_R	252_H	1.340	0.99
64_T	70_D	1.332	0.99
13_L	26_I	1.312	0.99
10_L	26_I	1.303	0.99
14_Q	22_F	1.289	0.99
275_I	278_V	1.287	0.99
282_L	286_F	1.278	0.99
306_L	322_A	1.277	0.99
317_L	322_A	1.267	0.98
26_I	51_V	1.265	0.98
190_M	198_V	1.260	0.98
154_A	185_V	1.253	0.98
210_M	214_L	1.251	0.98
152_A	304_A	1.249	0.98
354_I	358_F	1.240	0.98
199_V	225_Y	1.237	0.98
414_A	429_F	1.230	0.98
405_R	447_L	1.228	0.98
234_I	237_I	1.222	0.98
167_P	263_Q	1.213	0.98
42_A	76_F	1.205	0.98
161_P	263_Q	1.205	0.98
445_E	449_E	1.201	0.98
44_N	47_V	1.200	0.98
347_A	358_F	1.199	0.98
437_V	440_A	1.197	0.98
37_T	73_Q	1.194	0.98
342_R	365_D	1.192	0.98
10_L	22_F	1.187	0.98
8_Q	66_F	1.168	0.97
252_H	255_N	1.167	0.97
454_I	457_D	1.163	0.97
224_R	228_S	1.157	0.97
461_L	465_L	1.140	0.97
302_R	329_L	1.137	0.97
157_V	263_Q	1.136	0.97
203_S	240_F	1.128	0.97
460_N	464_T	1.127	0.97
319_G	323_F	1.120	0.97
313_N	341_N	1.116	0.97
49_D	53_D	1.103	0.96
423_P	435_T	1.100	0.96
438_L	442_R	1.095	0.96
48_L	76_F	1.094	0.96
30_Q	41_Y	1.089	0.96
381_K	391_V	1.086	0.96
155_R	188_G	1.086	0.96
50_W	55_Y	1.084	0.96
173_G	176_L	1.079	0.96
352_R	355_T	1.079	0.96
254_F	264_I	1.077	0.96
207_V	211_V	1.077	0.96
420_H	424_E	1.068	0.96
12_R	16_E	1.067	0.95
248_E	252_H	1.065	0.95
459_S	462_I	1.063	0.95
176_L	301_T	1.062	0.95
309_K	340_L	1.058	0.95
182_L	233_L	1.052	0.95
26_I	29_L	1.049	0.95
343_V	359_V	1.048	0.95
7_Q	11_A	1.048	0.95
452_H	455_K	1.047	0.95
204_E	208_Q	1.045	0.95
329_L	339_A	1.041	0.95
280_D	283_K	1.040	0.95
415_K	442_R	1.035	0.95
56_L	60_N	1.033	0.95
380_Q	394_L	1.033	0.95
278_V	282_L	1.029	0.95
269_D	281_R	1.027	0.94
397_K	432_R	1.021	0.94
172_G	294_I	1.014	0.94
30_Q	79_G	1.010	0.94
382_T	465_L	1.010	0.94
162_G	263_Q	1.008	0.94
12_R	66_F	1.006	0.94
12_R	15_D	1.003	0.94
33_L	71_A	1.003	0.94
187_N	291_T	1.002	0.94
449_E	455_K	1.001	0.94
49_D	52_R	0.997	0.94
132_V	187_N	0.996	0.94
45_R	49_D	0.994	0.93
234_I	250_F	0.992	0.93
239_F	252_H	0.988	0.93
244_E	277_G	0.987	0.93
299_L	323_F	0.987	0.93
256_A	260_G	0.983	0.93
158_A	189_I	0.982	0.93
21_E	55_Y	0.969	0.93
386_Y	464_T	0.967	0.92
210_M	219_I	0.967	0.92
201_M	331_S	0.966	0.92
213_A	219_I	0.966	0.92
387_Y	406_P	0.963	0.92
240_F	275_I	0.961	0.92
358_F	362_A	0.958	0.92
270_R	280_D	0.949	0.92
377_D	380_Q	0.945	0.92
251_F	254_F	0.945	0.92
394_L	410_A	0.941	0.91
379_I	418_T	0.939	0.91
132_V	182_L	0.938	0.91
234_I	266_L	0.935	0.91
13_L	58_N	0.932	0.91
166_N	254_F	0.931	0.91
42_A	78_V	0.924	0.91
408_Q	436_T	0.922	0.91
189_I	192_R	0.921	0.91
389_I	394_L	0.918	0.90
264_I	278_V	0.918	0.90
20_T	24_M	0.913	0.90
342_R	346_N	0.913	0.90
22_F	55_Y	0.912	0.90
43_P	47_V	0.908	0.90
378_N	465_L	0.907	0.90
287_G	291_T	0.900	0.89
169_F	291_T	0.897	0.89
382_T	464_T	0.896	0.89
257_L	262_Q	0.894	0.89
56_L	74_L	0.894	0.89
46_F	50_W	0.890	0.89
16_E	61_G	0.889	0.89
118_D	122_A	0.887	0.89
347_A	354_I	0.883	0.89
5_L	63_L	0.880	0.88
256_A	259_E	0.878	0.88
135_K	261_N	0.878	0.88
28_P	47_V	0.876	0.88
414_A	418_T	0.874	0.88
415_K	422_L	0.872	0.88
217_N	245_R	0.868	0.88
63_L	74_L	0.862	0.87
34_S	37_T	0.859	0.87
380_Q	428_A	0.854	0.87
254_F	263_Q	0.854	0.87
146_S	301_T	0.851	0.87
201_M	209_D	0.849	0.87
374_V	465_L	0.848	0.87
83_V	90_A	0.848	0.87
238_Q	269_D	0.846	0.86
214_L	223_K	0.844	0.86
10_L	27_R	0.840	0.86
343_V	354_I	0.839	0.86
230_D	262_Q	0.837	0.86
5_L	67_C	0.837	0.86
39_A	75_R	0.835	0.86
409_M	458_F	0.835	0.86
227_R	239_F	0.835	0.86
384_A	389_I	0.834	0.86
204_E	249_E	0.834	0.86
380_Q	410_A	0.828	0.85
241_A	275_I	0.827	0.85
454_I	458_F	0.827	0.85
415_K	438_L	0.825	0.85
453_D	459_S	0.822	0.85
422_L	437_V	0.819	0.85
212_K	216_N	0.819	0.85
179_T	269_D	0.813	0.84
339_A	363_L	0.812	0.84
166_N	263_Q	0.811	0.84
85_Q	119_N	0.809	0.84
188_G	357_D	0.809	0.84
323_F	327_K	0.808	0.84
118_D	121_P	0.807	0.84
22_F	27_R	0.803	0.83
38_L	48_L	0.802	0.83
39_A	77_E	0.800	0.83
247_Q	309_K	0.800	0.83
137_T	140_N	0.799	0.83
25_W	50_W	0.797	0.83
410_A	414_A	0.793	0.83
221_E	224_R	0.793	0.83
52_R	56_L	0.793	0.83
359_V	419_N	0.792	0.83
422_L	438_L	0.791	0.82
383_V	387_Y	0.790	0.82
239_F	243_K	0.787	0.82
9_C	29_L	0.787	0.82
251_F	255_N	0.787	0.82
156_Q	304_A	0.785	0.82
227_R	257_L	0.784	0.82
40_L	76_F	0.782	0.82
352_R	361_E	0.780	0.82
144_G	298_E	0.780	0.82
414_A	417_L	0.778	0.81
238_Q	266_L	0.778	0.81
361_E	364_R	0.778	0.81
202_H	205_R	0.775	0.81
335_E	363_L	0.775	0.81
208_Q	227_R	0.775	0.81
404_A	439_H	0.774	0.81
321_V	354_I	0.773	0.81
438_L	441_C	0.772	0.81
352_R	358_F	0.771	0.81
271_Y	275_I	0.769	0.81
5_L	9_C	0.769	0.81
457_D	461_L	0.768	0.81
308_K	311_D	0.768	0.81
157_V	166_N	0.767	0.80
418_T	421_S	0.764	0.80
169_F	286_F	0.763	0.80
21_E	24_M	0.762	0.80
418_T	423_P	0.759	0.80
12_R	62_L	0.759	0.80
41_Y	77_E	0.757	0.80
391_V	394_L	0.756	0.80
146_S	298_E	0.756	0.80
182_L	265_I	0.755	0.79
207_V	243_K	0.752	0.79
144_G	176_L	0.751	0.79
42_A	51_V	0.748	0.79
346_N	358_F	0.746	0.79
409_M	413_L	0.745	0.79
239_F	248_E	0.745	0.79
264_I	362_A	0.743	0.78
415_K	441_C	0.742	0.78
324_F	404_A	0.741	0.78
167_P	254_F	0.740	0.78
343_V	362_A	0.740	0.78
132_V	183_H	0.738	0.78
283_K	287_G	0.737	0.78
379_I	413_L	0.737	0.78
447_L	450_E	0.736	0.78
399_R	439_H	0.734	0.78
42_A	47_V	0.733	0.77
267_T	277_G	0.733	0.77
176_L	333_V	0.732	0.77
5_L	8_Q	0.731	0.77
133_N	183_H	0.730	0.77
55_Y	58_N	0.729	0.77
417_L	461_L	0.729	0.77
308_K	312_E	0.727	0.77
254_F	258_L	0.727	0.77
212_K	215_Q	0.726	0.77
203_S	403_V	0.723	0.76
409_M	450_E	0.720	0.76
251_F	269_D	0.719	0.76
220_E	224_R	0.718	0.76
206_F	253_T	0.717	0.76
417_L	462_I	0.717	0.76
139_D	188_G	0.717	0.76
398_R	403_V	0.714	0.76
405_R	432_R	0.713	0.75
10_L	14_Q	0.712	0.75
143_E	148_Q	0.712	0.75
16_E	62_L	0.711	0.75
29_L	51_V	0.711	0.75
207_V	210_M	0.711	0.75
13_L	62_L	0.710	0.75
401_R	405_R	0.710	0.75
17_L	26_I	0.709	0.75
463_R	466_S	0.709	0.75
418_T	422_L	0.708	0.75
359_V	362_A	0.703	0.74
25_W	28_P	0.700	0.74
223_K	253_T	0.700	0.74
411_M	429_F	0.699	0.74
149_L	290_L	0.698	0.74
296_P	365_D	0.694	0.73
44_N	78_V	0.692	0.73
237_I	286_F	0.690	0.73
149_L	291_T	0.689	0.73
90_A	120_V	0.688	0.73
22_F	76_F	0.684	0.72
186_G	198_V	0.683	0.72
36_N	73_Q	0.683	0.72
203_S	238_Q	0.681	0.72
176_L	326_A	0.680	0.72
33_L	67_C	0.680	0.72
182_L	235_D	0.680	0.72
87_P	121_P	0.679	0.72
25_W	408_Q	0.677	0.72
141_F	181_L	0.676	0.72
209_D	363_L	0.675	0.71
308_K	385_E	0.674	0.71
126_P	197_K	0.673	0.71
4_S	7_Q	0.672	0.71
234_I	291_T	0.672	0.71
372_K	406_P	0.670	0.71
159_D	188_G	0.668	0.71
79_G	82_P	0.668	0.71
145_K	292_V	0.667	0.70
432_R	453_D	0.666	0.70
13_L	17_L	0.665	0.70
182_L	398_R	0.665	0.70
40_L	436_T	0.665	0.70
247_Q	278_V	0.664	0.70
61_G	65_S	0.661	0.70
86_T	90_A	0.661	0.70
162_G	421_S	0.661	0.70
301_T	304_A	0.661	0.70
8_Q	12_R	0.660	0.70
160_N	163_G	0.659	0.70
427_D	431_G	0.657	0.69
174_T	205_R	0.657	0.69
413_L	417_L	0.657	0.69
208_Q	253_T	0.655	0.69
460_N	463_R	0.655	0.69
456_E	460_N	0.654	0.69
8_Q	11_A	0.653	0.69
345_A	349_F	0.649	0.68
117_W	122_A	0.648	0.68
401_R	408_Q	0.647	0.68
324_F	328_R	0.646	0.68
157_V	293_A	0.644	0.68
245_R	248_E	0.644	0.68
302_R	306_L	0.644	0.68
439_H	443_K	0.641	0.67
289_G	434_H	0.640	0.67
235_D	269_D	0.640	0.67
60_N	64_T	0.638	0.67
208_Q	223_K	0.637	0.67
43_P	78_V	0.637	0.67
240_F	292_V	0.634	0.67
210_M	217_N	0.633	0.67
157_V	167_P	0.633	0.67
271_Y	291_T	0.633	0.67
38_L	71_A	0.632	0.66
378_N	381_K	0.632	0.66
155_R	159_D	0.632	0.66
219_I	432_R	0.632	0.66
340_L	363_L	0.631	0.66
176_L	300_E	0.631	0.66
276_N	341_N	0.631	0.66
167_P	255_N	0.630	0.66
457_D	460_N	0.628	0.66
417_L	423_P	0.627	0.66
405_R	457_D	0.626	0.66
393_D	402_S	0.625	0.66
253_T	301_T	0.623	0.65
394_L	404_A	0.623	0.65
423_P	429_F	0.623	0.65
14_Q	55_Y	0.623	0.65
91_V	118_D	0.620	0.65
159_D	192_R	0.619	0.65
252_H	345_A	0.619	0.65
225_Y	237_I	0.617	0.65
63_L	67_C	0.616	0.64
393_D	409_M	0.616	0.64
57_N	353_A	0.616	0.64
258_L	266_L	0.615	0.64
87_P	93_S	0.614	0.64
318_P	353_A	0.612	0.64
120_V	123_P	0.611	0.64
278_V	283_K	0.611	0.64
253_T	257_L	0.610	0.64
176_L	332_N	0.610	0.64
247_Q	279_E	0.610	0.64
229_V	310_A	0.609	0.64
382_T	461_L	0.608	0.63
82_P	86_T	0.608	0.63
261_N	266_L	0.607	0.63
84_T	90_A	0.604	0.63
88_Q	93_S	0.604	0.63
238_Q	338_G	0.602	0.63
296_P	332_N	0.602	0.63
52_R	60_N	0.602	0.63
302_R	330_R	0.602	0.63
409_M	444_I	0.601	0.63
206_F	227_R	0.599	0.62
405_R	409_M	0.599	0.62
137_T	187_N	0.598	0.62
399_R	433_D	0.598	0.62
435_T	439_H	0.598	0.62
405_R	444_I	0.597	0.62
146_S	294_I	0.597	0.62
311_D	317_L	0.595	0.62
156_Q	295_E	0.593	0.61
31_A	79_G	0.592	0.61
238_Q	250_F	0.591	0.61
27_R	154_A	0.591	0.61
380_Q	414_A	0.590	0.61
153_A	331_S	0.590	0.61
219_I	253_T	0.590	0.61
156_Q	293_A	0.590	0.61
14_Q	29_L	0.589	0.61
188_G	308_K	0.588	0.61
375_T	378_N	0.588	0.61
382_T	385_E	0.586	0.61
204_E	252_H	0.586	0.61
396_S	438_L	0.586	0.61
214_L	228_S	0.586	0.61
170_L	292_V	0.585	0.60
136_H	201_M	0.584	0.60
174_T	342_R	0.584	0.60
247_Q	293_A	0.584	0.60
290_L	342_R	0.581	0.60
253_T	256_A	0.580	0.60
235_D	338_G	0.580	0.60
245_R	422_L	0.580	0.60
38_L	67_C	0.580	0.60
413_L	461_L	0.578	0.60
237_I	267_T	0.578	0.60
183_H	186_G	0.578	0.60
325_I	363_L	0.577	0.59
83_V	195_N	0.576	0.59
31_A	77_E	0.575	0.59
165_Y	287_G	0.575	0.59
58_N	61_G	0.575	0.59
298_E	301_T	0.574	0.59
458_F	462_I	0.574	0.59
277_G	283_K	0.573	0.59
314_D	391_V	0.571	0.59
401_R	448_R	0.570	0.58
229_V	465_L	0.569	0.58
151_R	187_N	0.568	0.58
203_S	234_I	0.567	0.58
241_A	270_R	0.567	0.58
226_Y	254_F	0.566	0.58
146_S	321_V	0.566	0.58
214_L	253_T	0.565	0.58
88_Q	357_D	0.564	0.58
345_A	418_T	0.563	0.58
83_V	89_A	0.563	0.58
54_K	432_R	0.563	0.58
255_N	285_R	0.561	0.57
159_D	325_I	0.561	0.57
406_P	409_M	0.559	0.57
83_V	91_V	0.559	0.57
84_T	120_V	0.558	0.57
50_W	403_V	0.557	0.57
279_E	283_K	0.557	0.57
381_K	424_E	0.556	0.57
400_S	404_A	0.556	0.57
92_T	117_W	0.555	0.56
74_L	118_D	0.554	0.56
210_M	223_K	0.554	0.56
378_N	382_T	0.554	0.56
422_L	435_T	0.554	0.56
140_N	313_N	0.554	0.56
87_P	91_V	0.553	0.56
40_L	191_A	0.552	0.56
246_S	375_T	0.551	0.56
389_I	404_A	0.551	0.56
258_L	341_N	0.550	0.56
267_T	270_R	0.549	0.56
268_S	286_F	0.549	0.56
420_H	428_A	0.548	0.56
18_P	21_E	0.548	0.56
427_D	453_D	0.548	0.56
220_E	398_R	0.547	0.55
148_Q	155_R	0.547	0.55
251_F	286_F	0.546	0.55
145_K	248_E	0.544	0.55
270_R	277_G	0.543	0.55
149_L	292_V	0.542	0.55
17_L	25_W	0.542	0.55
25_W	247_Q	0.541	0.55
411_M	439_H	0.541	0.55
154_A	157_V	0.540	0.54
301_T	349_F	0.539	0.54
377_D	381_K	0.538	0.54
453_D	457_D	0.537	0.54
127_T	197_K	0.537	0.54
26_I	272_P	0.537	0.54
62_L	202_H	0.537	0.54
33_L	397_K	0.536	0.54
262_Q	271_Y	0.536	0.54
25_W	436_T	0.536	0.54
432_R	439_H	0.536	0.54
305_I	333_V	0.536	0.54
261_N	343_V	0.535	0.54
211_V	239_F	0.534	0.54
186_G	340_L	0.533	0.53
389_I	464_T	0.531	0.53
231_A	395_L	0.531	0.53
190_M	194_P	0.530	0.53
129_R	190_M	0.529	0.53
145_K	323_F	0.529	0.53
223_K	261_N	0.528	0.53
238_Q	281_R	0.527	0.53
201_M	373_L	0.527	0.53
455_K	462_I	0.526	0.53
81_K	85_Q	0.525	0.52
223_K	227_R	0.525	0.52
266_L	286_F	0.525	0.52
41_Y	76_F	0.524	0.52
233_L	245_R	0.524	0.52
427_D	432_R	0.523	0.52
277_G	333_V	0.522	0.52
14_Q	59_I	0.521	0.52
320_E	356_I	0.521	0.52
87_P	92_T	0.520	0.52
19_A	465_L	0.520	0.52
386_Y	461_L	0.520	0.52
204_E	248_E	0.520	0.52
168_L	290_L	0.518	0.51
279_E	359_V	0.518	0.51
37_T	185_V	0.517	0.51
200_Y	267_T	0.516	0.51
4_S	53_D	0.515	0.51
380_Q	420_H	0.515	0.51
433_D	443_K	0.513	0.51
451_S	454_I	0.513	0.51
169_F	272_P	0.513	0.51
87_P	123_P	0.513	0.51
400_S	406_P	0.512	0.51
382_T	386_Y	0.512	0.51
421_S	437_V	0.511	0.50
415_K	423_P	0.511	0.50
189_I	195_N	0.511	0.50
369_L	375_T	0.510	0.50
88_Q	91_V	0.509	0.50
275_I	415_K	0.506	0.50
52_R	307_M	0.506	0.50
174_T	183_H	0.506	0.50
32_E	445_E	0.506	0.50
40_L	56_L	0.505	0.50
270_R	282_L	0.505	0.50
186_G	267_T	0.504	0.50
165_Y	252_H	0.504	0.50
235_D	263_Q	0.504	0.50
204_E	243_K	0.503	0.49
167_P	235_D	0.503	0.49
408_Q	443_K	0.502	0.49
208_Q	275_I	0.502	0.49
207_V	223_K	0.501	0.49
65_S	124_A	0.500	0.49

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2z4sA	1	0.5118	100	0.401	Contact Map
1l8qA	1	0.6788	100	0.583	Contact Map
3nbxX	1	0.6724	100	0.661	Contact Map
3bosA	2	0.4925	100	0.763	Contact Map
4w5wA	1	0.5054	100	0.782	Contact Map
1j1vA	1	0.2013	100	0.784	Contact Map
3pvvA	1	0.1991	100	0.79	Contact Map
2qgzA	1	0.3683	100	0.793	Contact Map
2r44A	1	0.5675	100	0.817	Contact Map
3u61B	3	0.6574	100	0.828	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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