CARB - ECOLI - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

CARB - Carbamoyl-phosphate synthase large chain

UniProt:	P00968	Sequences: MPKRTDIKSILILGAGPIVIGQACEFDYSGAQACKALREEGYRVILVNSNPATIMTDPEMADATYIEPIHWEVVRKIIEKERPDAVLPTMGGQTALNCALELERQGVLEEFGVTMIGATADAIDKAEDRRRFDVAMKKIGLETARSGIAHTMEEALAVAADVGFPCIIRPSFTMGGSGGGIAYNREEFEEICARGLDLSPTKELLIDESLIGWKEYEMEVVRDKNDNCIIVCSIENFDAMGIHTGDSITVAPAQTLTDKEYQIMRNASMAVLREIGVETGGSNVQFAVNPKNGRLIVIEMNPRVSRSSALASKATGFPIAKVAAKLAVGYTLDELMNDITGGRTPASFEPSIDYVVTKIPRFNFEKFAGANDRLTTQMKSVGEVMAIGRTQQESLQKALRGLEVGATGFDPKVSLDDPEALTKIRRELKDAGADRIWYIADAFRAGLSVDGVFNLTNIDRWFLVQIEELVRLEEKVAEVGITGLNADFLRQLKRKGFADARLAKLAGVREAEIRKLRDQYDLHPVYKRVDTCAAEFATDTAYMYSTYEEECEANPSTDREKIMVLGGGPNRIGQGIEFDYCCVHASLALREDGYETIMVNCNPETVSTDYDTSDRLYFEPVTLEDVLEIVRIEKPKGVIVQYGGQTPLKLARALEAAGVPVIGTSPDAIDRAEDRERFQHAVERLKLKQPANATVTAIEMAVEKAKEIGYPLVVRPSYVLGGRAMEIVYDEADLRRYFQTAVSVSNDAPVLLDHFLDDAVEVDVDAICDGEMVLIGGIMEHIEQAGVHSGDSACSLPAYTLSQEIQDVMRQQVQKLAFELQVRGLMNVQFAVKNNEVYLIEVNPRAARTVPFVSKATGVPLAKVAARVMAGKSLAEQGVTKEVIPPYYSVKEVVLPFNKFPGVDPLLGPEMRSTGEVMGVGRTFAEAFAKAQLGSNSTMKKHGRALLSVREGDKERVVDLAAKLLKQGFELDATHGTAIVLGEAGINPRLVNKVHEGRPHIQDRIKNGEYTYIINTTSGRRAIEDSRVIRRSALQYKVHYDTTLNGGFATAMALNADATEKVISVQEMHAQIK	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10135
Length:	1073 (1050)
Sequences:	2884 (1182)
Seq/√Len:	36.5

ECOLI - CARB
BACSU - CARB CARY
HALSA - CARB
SULSO - CARB

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
357_T	394_S	6.939	1.00
467_E	471_R	5.566	1.00
226_D	273_R	4.733	1.00
9_S	43_R	4.585	1.00
9_S	45_I	4.529	1.00
706_K	731_E	4.432	1.00
563_M	599_V	4.361	1.00
289_N	292_N	4.336	1.00
684_R	819_E	4.302	1.00
82_R	111_F	4.296	1.00
104_R	124_D	4.268	1.00
69_I	98_C	4.262	1.00
867_R	872_K	4.174	1.00
667_D	677_R	4.114	1.00
947_L	961_A	3.761	1.00
155_A	192_C	3.632	1.00
560_E	636_K	3.584	1.00
623_L	627_L	3.571	1.00
441_D	445_A	3.555	1.00
192_C	204_L	3.538	1.00
138_K	274_E	3.406	1.00
289_N	294_R	3.403	1.00
400_R	625_D	3.403	1.00
218_M	233_S	3.386	1.00
921_G	926_E	3.284	1.00
10_I	42_Y	3.278	1.00
811_Q	815_K	3.253	1.00
799_Y	888_Y	3.243	1.00
944_R	970_E	3.218	1.00
771_E	873_S	3.142	1.00
237_F	466_I	3.102	1.00
75_R	110_E	3.091	1.00
264_M	295_L	3.078	1.00
439_I	452_V	3.059	1.00
79_E	111_F	3.057	1.00
963_K	1055_N	3.054	1.00
233_S	253_A	3.044	1.00
78_I	111_F	2.998	1.00
873_S	876_E	2.989	1.00
599_V	629_I	2.988	1.00
443_F	463_L	2.980	1.00
712_L	752_L	2.955	1.00
145_R	208_E	2.939	1.00
472_L	495_K	2.920	1.00
75_R	79_E	2.901	1.00
518_D	631_R	2.898	1.00
42_Y	328_V	2.898	1.00
156_L	189_E	2.870	1.00
160_A	185_R	2.834	1.00
872_K	876_E	2.814	1.00
75_R	111_F	2.768	1.00
803_Q	807_D	2.730	1.00
702_V	735_R	2.720	1.00
551_C	632_I	2.715	1.00
450_D	460_R	2.714	1.00
766_A	813_V	2.705	1.00
43_R	63_A	2.702	1.00
767_I	868_V	2.678	1.00
980_V	984_A	2.675	1.00
4_R	114_T	2.615	1.00
130_R	134_V	2.587	1.00
425_R	451_G	2.565	1.00
710_Y	731_E	2.562	1.00
563_M	630_V	2.562	1.00
443_F	449_V	2.558	1.00
486_A	490_R	2.555	1.00
395_L	436_I	2.550	1.00
10_I	328_V	2.539	1.00
965_L	987_N	2.529	1.00
693_A	707_E	2.528	1.00
185_R	189_E	2.523	1.00
149_A	158_V	2.519	1.00
392_Q	465_Q	2.484	1.00
892_E	931_A	2.455	1.00
74_V	98_C	2.439	1.00
559_R	595_E	2.435	1.00
159_A	164_F	2.381	1.00
151_T	154_E	2.377	1.00
388_G	393_E	2.377	1.00
490_R	494_R	2.375	1.00
978_A	988_P	2.362	1.00
873_S	877_Q	2.360	1.00
630_V	659_V	2.358	1.00
951_E	954_K	2.345	1.00
688_K	812_Q	2.330	1.00
71_W	101_E	2.321	0.99
591_E	863_K	2.311	0.99
964_L	1051_A	2.285	0.99
75_R	105_Q	2.273	0.99
693_A	704_K	2.269	0.99
730_D	733_D	2.267	0.99
958_V	980_V	2.259	0.99
814_Q	818_F	2.247	0.99
150_H	203_E	2.243	0.99
47_V	77_I	2.243	0.99
668_A	821_Q	2.228	0.99
475_K	491_Q	2.225	0.99
141_L	270_A	2.215	0.99
208_E	294_R	2.210	0.99
864_V	877_Q	2.205	0.99
218_M	253_A	2.197	0.99
272_L	284_V	2.195	0.99
39_E	325_K	2.175	0.99
741_A	745_S	2.162	0.99
447_L	451_G	2.154	0.99
563_M	629_I	2.153	0.99
509_R	512_E	2.149	0.99
970_E	989_R	2.143	0.99
164_F	185_R	2.139	0.99
1014_I	1047_G	2.123	0.99
514_R	627_L	2.121	0.99
808_V	811_Q	2.115	0.99
958_V	984_A	2.114	0.99
142_E	294_R	2.109	0.99
420_A	423_K	2.106	0.99
944_R	972_D	2.105	0.99
772_M	875_A	2.093	0.99
488_F	492_L	2.093	0.99
655_E	667_D	2.087	0.99
396_Q	497_F	2.084	0.99
443_F	452_V	2.083	0.99
776_G	861_L	2.080	0.99
76_K	79_E	2.070	0.99
687_L	812_Q	2.060	0.99
147_G	161_D	2.059	0.99
100_L	120_A	2.040	0.99
271_V	297_V	2.030	0.99
392_Q	468_E	2.024	0.99
372_D	433_A	2.017	0.99
71_W	105_Q	2.011	0.99
762_V	801_L	2.005	0.98
511_A	656_A	2.005	0.98
242_I	431_A	2.005	0.98
288_V	295_L	2.004	0.98
377_Q	899_K	2.002	0.98
702_V	731_E	1.999	0.98
449_V	463_L	1.997	0.98
141_L	267_A	1.990	0.98
731_E	735_R	1.988	0.98
518_D	523_H	1.974	0.98
479_V	485_N	1.969	0.98
978_A	990_L	1.968	0.98
164_F	184_N	1.967	0.98
652_R	656_A	1.961	0.98
439_I	458_I	1.959	0.98
421_L	445_A	1.937	0.98
75_R	107_V	1.936	0.98
991_V	1004_R	1.928	0.98
184_N	187_E	1.918	0.98
171_S	203_E	1.914	0.98
741_A	750_V	1.902	0.98
516_L	520_Y	1.898	0.98
670_D	677_R	1.896	0.98
697_A	700_M	1.891	0.98
670_D	718_Y	1.889	0.98
66_I	918_M	1.887	0.98
151_T	202_K	1.876	0.98
159_A	166_C	1.875	0.98
182_A	191_I	1.874	0.98
804_E	835_N	1.873	0.98
150_H	154_E	1.872	0.98
592_D	867_R	1.862	0.98
691_A	707_E	1.856	0.97
591_E	867_R	1.855	0.97
703_E	707_E	1.854	0.97
474_E	477_A	1.850	0.97
47_V	74_V	1.845	0.97
78_I	113_V	1.842	0.97
999_P	1003_D	1.841	0.97
103_E	120_A	1.840	0.97
764_V	813_V	1.840	0.97
40_E	325_K	1.839	0.97
79_E	110_E	1.829	0.97
253_A	261_Y	1.793	0.97
448_S	451_G	1.787	0.97
688_K	836_E	1.784	0.97
499_D	517_R	1.773	0.97
9_S	63_A	1.763	0.97
147_G	158_V	1.762	0.97
443_F	466_I	1.755	0.96
523_H	631_R	1.755	0.96
617_Y	633_E	1.745	0.96
768_C	818_F	1.744	0.96
196_L	202_K	1.741	0.96
736_R	740_T	1.740	0.96
428_L	442_A	1.728	0.96
390_T	548_E	1.725	0.96
762_V	832_V	1.723	0.96
562_I	662_I	1.718	0.96
135_A	274_E	1.710	0.96
168_I	204_L	1.710	0.96
453_F	463_L	1.708	0.96
1013_I	1033_A	1.706	0.96
695_V	704_K	1.704	0.96
742_V	750_V	1.694	0.96
681_A	816_L	1.689	0.96
124_D	131_R	1.684	0.96
440_A	444_R	1.667	0.95
623_L	653_A	1.656	0.95
762_V	809_M	1.653	0.95
808_V	812_Q	1.652	0.95
384_V	401_G	1.646	0.95
802_S	805_I	1.645	0.95
515_K	519_Q	1.644	0.95
103_E	109_E	1.636	0.95
440_A	466_I	1.627	0.95
953_D	1016_T	1.625	0.95
168_I	206_I	1.622	0.94
183_Y	187_E	1.618	0.94
560_E	594_Y	1.616	0.94
972_D	1010_Y	1.610	0.94
802_S	835_N	1.601	0.94
538_T	541_A	1.599	0.94
691_A	754_H	1.593	0.94
766_A	826_M	1.592	0.94
468_E	495_K	1.592	0.94
86_V	113_V	1.588	0.94
832_V	837_V	1.588	0.94
133_D	137_K	1.587	0.94
407_T	504_K	1.586	0.94
260_E	293_G	1.580	0.94
164_F	188_F	1.574	0.94
592_D	870_A	1.574	0.94
73_V	77_I	1.571	0.93
724_A	741_A	1.571	0.93
125_K	274_E	1.571	0.93
275_I	300_M	1.570	0.93
71_W	74_V	1.569	0.93
1031_R	1035_Q	1.555	0.93
168_I	188_F	1.554	0.93
218_M	268_S	1.548	0.93
469_L	497_F	1.547	0.93
623_L	657_A	1.537	0.93
688_K	808_V	1.537	0.93
681_A	819_E	1.534	0.93
798_A	806_Q	1.531	0.93
808_V	837_V	1.530	0.93
485_N	488_F	1.530	0.93
224_K	331_T	1.528	0.92
489_L	516_L	1.523	0.92
679_Q	689_Q	1.520	0.92
993_K	1025_D	1.516	0.92
71_W	98_C	1.513	0.92
149_A	154_E	1.507	0.92
513_I	516_L	1.506	0.92
516_L	519_Q	1.503	0.92
589_L	596_T	1.502	0.92
391_Q	461_W	1.500	0.92
502_L	506_A	1.498	0.92
762_V	837_V	1.495	0.92
589_L	870_A	1.493	0.92
807_D	810_R	1.486	0.91
472_L	492_L	1.483	0.91
528_R	543_M	1.482	0.91
741_A	744_V	1.477	0.91
107_V	111_F	1.475	0.91
805_I	837_V	1.474	0.91
805_I	832_V	1.468	0.91
510_E	514_R	1.468	0.91
923_T	926_E	1.466	0.91
476_V	492_L	1.456	0.91
447_L	452_V	1.453	0.90
805_I	835_N	1.451	0.90
225_N	331_T	1.447	0.90
1005_I	1038_V	1.447	0.90
793_A	892_E	1.446	0.90
395_L	409_F	1.442	0.90
237_F	248_I	1.441	0.90
421_L	451_G	1.440	0.90
767_I	861_L	1.437	0.90
134_V	138_K	1.432	0.90
682_V	839_L	1.426	0.90
982_G	990_L	1.422	0.89
636_K	660_P	1.415	0.89
639_I	866_A	1.415	0.89
774_L	879_V	1.412	0.89
425_R	447_L	1.408	0.89
425_R	455_L	1.408	0.89
668_A	671_R	1.408	0.89
562_I	870_A	1.405	0.89
969_F	1054_L	1.397	0.89
101_E	104_R	1.397	0.89
677_R	718_Y	1.397	0.89
399_L	436_I	1.396	0.89
237_F	439_I	1.395	0.89
518_D	628_E	1.392	0.88
149_A	155_A	1.391	0.88
453_F	457_N	1.390	0.88
973_A	988_P	1.390	0.88
500_A	510_E	1.382	0.88
812_Q	837_V	1.375	0.88
872_K	877_Q	1.370	0.88
152_M	188_F	1.367	0.87
322_V	338_D	1.365	0.87
88_P	99_A	1.365	0.87
486_A	520_Y	1.365	0.87
144_A	296_I	1.364	0.87
555_P	615_R	1.357	0.87
866_A	870_A	1.355	0.87
671_R	819_E	1.353	0.87
443_F	467_E	1.352	0.87
705_A	710_Y	1.351	0.87
562_I	589_L	1.345	0.87
813_V	830_F	1.342	0.87
954_K	976_G	1.338	0.86
157_A	160_A	1.337	0.86
424_I	452_V	1.334	0.86
949_V	957_V	1.330	0.86
69_I	74_V	1.327	0.86
638_V	659_V	1.325	0.86
979_I	983_E	1.324	0.86
469_L	495_K	1.320	0.86
768_C	773_V	1.310	0.85
484_L	489_L	1.309	0.85
808_V	836_E	1.309	0.85
70_H	73_V	1.300	0.85
975_H	990_L	1.293	0.84
125_K	138_K	1.290	0.84
523_H	628_E	1.289	0.84
992_N	1000_H	1.284	0.84
756_L	833_K	1.283	0.84
11_L	86_V	1.273	0.83
159_A	188_F	1.273	0.83
561_K	595_E	1.269	0.83
982_G	988_P	1.269	0.83
687_L	837_V	1.268	0.83
343_R	539_D	1.265	0.83
1052_M	1055_N	1.263	0.83
479_V	488_F	1.262	0.83
407_T	500_A	1.261	0.83
816_L	828_V	1.260	0.83
257_T	260_E	1.259	0.83
263_I	288_V	1.256	0.83
6_D	114_T	1.255	0.83
680_H	684_R	1.250	0.82
627_L	659_V	1.247	0.82
508_V	513_I	1.242	0.82
444_R	473_E	1.241	0.82
40_E	330_Y	1.240	0.82
237_F	250_V	1.240	0.82
152_M	156_L	1.236	0.82
508_V	512_E	1.236	0.82
962_A	966_K	1.234	0.81
484_L	506_A	1.232	0.81
679_Q	692_N	1.230	0.81
465_Q	468_E	1.228	0.81
596_T	870_A	1.227	0.81
806_Q	810_R	1.220	0.81
639_I	869_M	1.219	0.81
472_L	488_F	1.214	0.80
146_S	207_D	1.204	0.80
476_V	505_L	1.204	0.80
100_L	131_R	1.204	0.80
452_V	466_I	1.202	0.80
86_V	108_L	1.199	0.80
963_K	1051_A	1.199	0.80
396_Q	469_L	1.197	0.79
447_L	455_L	1.193	0.79
738_F	742_V	1.192	0.79
440_A	470_V	1.191	0.79
461_W	465_Q	1.184	0.79
553_A	632_I	1.184	0.79
221_V	322_V	1.184	0.79
194_R	198_L	1.183	0.79
131_R	134_V	1.182	0.79
406_A	437_W	1.181	0.78
742_V	745_S	1.173	0.78
961_A	971_L	1.171	0.78
421_L	425_R	1.163	0.77
476_V	502_L	1.163	0.77
556_S	595_E	1.161	0.77
592_D	872_K	1.159	0.77
738_F	741_A	1.154	0.77
125_K	135_A	1.153	0.77
395_L	466_I	1.153	0.77
392_Q	495_K	1.147	0.76
778_I	806_Q	1.147	0.76
126_A	284_V	1.145	0.76
453_F	460_R	1.145	0.76
137_K	143_T	1.140	0.76
47_V	102_L	1.138	0.76
71_W	107_V	1.137	0.76
100_L	124_D	1.136	0.76
250_V	357_T	1.135	0.76
587_L	612_T	1.132	0.75
170_P	179_G	1.131	0.75
524_P	547_Y	1.130	0.75
267_A	295_L	1.129	0.75
778_I	810_R	1.128	0.75
71_W	75_R	1.128	0.75
142_E	208_E	1.123	0.75
795_S	924_F	1.122	0.75
475_K	488_F	1.122	0.75
527_K	550_E	1.118	0.75
390_T	394_S	1.114	0.74
625_D	628_E	1.113	0.74
428_L	456_T	1.112	0.74
101_E	105_Q	1.112	0.74
330_Y	335_L	1.107	0.74
972_D	989_R	1.107	0.74
1027_R	1031_R	1.104	0.74
258_D	262_Q	1.104	0.74
868_V	877_Q	1.100	0.73
124_D	172_F	1.100	0.73
341_G	539_D	1.096	0.73
19_V	177_S	1.096	0.73
773_V	818_F	1.094	0.73
812_Q	830_F	1.093	0.73
427_E	432_G	1.090	0.73
565_L	626_V	1.090	0.73
155_A	206_I	1.087	0.72
121_D	131_R	1.086	0.72
13_L	69_I	1.086	0.72
34_C	60_M	1.085	0.72
228_C	269_M	1.085	0.72
188_F	206_I	1.077	0.72
396_Q	408_G	1.077	0.72
208_E	296_I	1.075	0.72
133_D	207_D	1.074	0.71
262_Q	265_R	1.073	0.71
475_K	479_V	1.073	0.71
940_K	943_G	1.072	0.71
384_V	398_A	1.070	0.71
322_V	335_L	1.064	0.71
427_E	438_Y	1.064	0.71
155_A	168_I	1.063	0.71
852_F	918_M	1.063	0.71
218_M	228_C	1.061	0.71
99_A	115_M	1.061	0.71
1014_I	1044_L	1.060	0.70
441_D	444_R	1.060	0.70
13_L	74_V	1.057	0.70
449_V	467_E	1.057	0.70
621_V	650_L	1.054	0.70
586_S	613_S	1.051	0.70
489_L	522_L	1.047	0.70
220_V	230_I	1.046	0.69
628_E	631_R	1.045	0.69
266_N	270_A	1.044	0.69
184_N	998_R	1.043	0.69
126_A	724_A	1.043	0.69
259_K	293_G	1.042	0.69
390_T	495_K	1.041	0.69
192_C	206_I	1.040	0.69
13_L	95_A	1.039	0.69
227_N	331_T	1.039	0.69
627_L	657_A	1.036	0.69
687_L	808_V	1.035	0.69
813_V	828_V	1.035	0.69
250_V	391_Q	1.035	0.69
221_V	272_L	1.034	0.69
724_A	742_V	1.034	0.69
38_R	60_M	1.034	0.69
424_I	445_A	1.033	0.68
867_R	877_Q	1.029	0.68
189_E	193_A	1.029	0.68
207_D	210_L	1.027	0.68
214_K	459_D	1.023	0.68
992_N	999_P	1.022	0.68
718_Y	748_A	1.019	0.67
971_L	988_P	1.017	0.67
816_L	839_L	1.016	0.67
514_R	657_A	1.015	0.67
503_A	509_R	1.015	0.67
406_A	412_K	1.014	0.67
818_F	821_Q	1.012	0.67
735_R	739_Q	1.010	0.67
615_R	633_E	1.009	0.67
389_R	548_E	1.009	0.67
225_N	333_D	1.008	0.67
556_S	561_K	1.007	0.66
503_A	513_I	1.006	0.66
227_N	347_S	1.006	0.66
696_T	700_M	1.004	0.66
228_C	273_R	1.002	0.66
141_L	297_V	1.000	0.66
1017_T	1026_S	1.000	0.66
823_R	868_V	0.999	0.66
228_C	272_L	0.998	0.66
798_A	801_L	0.997	0.66
889_S	920_V	0.997	0.66
998_R	1003_D	0.996	0.66
337_N	340_T	0.996	0.66
586_S	596_T	0.995	0.66
452_V	463_L	0.995	0.66
728_V	750_V	0.993	0.65
996_E	1000_H	0.993	0.65
428_L	438_Y	0.992	0.65
994_V	1002_Q	0.989	0.65
449_V	464_V	0.987	0.65
793_A	893_V	0.986	0.65
464_V	467_E	0.981	0.64
466_I	470_V	0.980	0.64
164_F	189_E	0.980	0.64
442_A	447_L	0.980	0.64
947_L	981_L	0.980	0.64
291_K	457_N	0.979	0.64
8_K	43_R	0.979	0.64
410_D	504_K	0.978	0.64
527_K	548_E	0.978	0.64
279_T	326_L	0.975	0.64
1012_Y	1041_D	0.972	0.64
480_G	484_L	0.971	0.64
85_A	88_P	0.970	0.64
191_I	195_G	0.968	0.63
389_R	527_K	0.968	0.63
168_I	192_C	0.967	0.63
234_I	249_T	0.967	0.63
925_A	1052_M	0.965	0.63
945_A	961_A	0.963	0.63
887_Y	920_V	0.961	0.63
344_T	348_F	0.961	0.63
271_V	635_P	0.960	0.63
253_A	352_I	0.959	0.63
159_A	192_C	0.959	0.63
36_A	335_L	0.959	0.63
472_L	491_Q	0.958	0.63
338_D	610_Y	0.958	0.63
141_L	284_V	0.953	0.62
45_I	77_I	0.952	0.62
856_A	889_S	0.952	0.62
512_E	515_K	0.950	0.62
121_D	125_K	0.946	0.62
486_A	522_L	0.945	0.61
4_R	42_Y	0.945	0.61
472_L	475_K	0.945	0.61
957_V	981_L	0.944	0.61
1_M	7_I	0.944	0.61
945_A	1014_I	0.942	0.61
218_M	261_Y	0.941	0.61
468_E	472_L	0.941	0.61
355_V	394_S	0.941	0.61
954_K	977_T	0.940	0.61
262_Q	536_F	0.940	0.61
107_V	110_E	0.938	0.61
359_I	362_F	0.938	0.61
1005_I	1032_S	0.937	0.61
780_E	800_T	0.935	0.61
784_Q	1045_N	0.934	0.61
701_A	738_F	0.934	0.61
796_L	853_V	0.933	0.60
262_Q	535_E	0.932	0.60
595_E	615_R	0.932	0.60
35_K	611_D	0.931	0.60
524_P	628_E	0.928	0.60
1018_S	1024_E	0.928	0.60
154_E	157_A	0.927	0.60
742_V	748_A	0.927	0.60
421_L	447_L	0.927	0.60
24_C	570_N	0.925	0.60
480_G	506_A	0.923	0.60
268_S	286_F	0.919	0.59
144_A	210_L	0.918	0.59
221_V	229_I	0.915	0.59
642_Y	865_A	0.912	0.59
972_D	1004_R	0.910	0.59
995_H	1000_H	0.909	0.58
993_K	1029_I	0.909	0.58
248_I	436_I	0.909	0.58
682_V	686_K	0.908	0.58
1005_I	1036_Y	0.908	0.58
153_E	157_A	0.906	0.58
1005_I	1029_I	0.905	0.58
744_V	750_V	0.903	0.58
773_V	814_Q	0.903	0.58
180_G	191_I	0.902	0.58
738_F	745_S	0.901	0.58
156_L	185_R	0.899	0.58
698_I	735_R	0.896	0.57
941_K	1054_L	0.895	0.57
381_V	570_N	0.893	0.57
978_A	982_G	0.892	0.57
878_G	883_V	0.887	0.57
522_L	547_Y	0.886	0.56
974_T	977_T	0.886	0.56
11_L	78_I	0.883	0.56
810_R	883_V	0.882	0.56
453_F	458_I	0.882	0.56
166_C	188_F	0.881	0.56
944_R	1011_T	0.881	0.56
982_G	987_N	0.880	0.56
809_M	813_V	0.879	0.56
975_H	996_E	0.879	0.56
164_F	635_P	0.878	0.56
213_W	296_I	0.877	0.56
359_I	398_A	0.875	0.56
207_D	621_V	0.875	0.56
258_D	536_F	0.875	0.56
133_D	148_I	0.874	0.55
157_A	161_D	0.874	0.55
759_A	831_A	0.874	0.55
745_S	750_V	0.873	0.55
210_L	240_M	0.872	0.55
287_A	296_I	0.872	0.55
184_N	1007_N	0.872	0.55
585_A	639_I	0.871	0.55
944_R	989_R	0.871	0.55
265_R	349_E	0.870	0.55
396_Q	461_W	0.870	0.55
226_D	230_I	0.868	0.55
1050_T	1054_L	0.868	0.55
262_Q	348_F	0.868	0.55
552_E	555_P	0.865	0.55
954_K	993_K	0.864	0.55
738_F	750_V	0.861	0.54
404_V	437_W	0.861	0.54
949_V	961_A	0.859	0.54
267_A	271_V	0.859	0.54
168_I	191_I	0.859	0.54
152_M	155_A	0.859	0.54
167_I	181_I	0.859	0.54
348_F	535_E	0.858	0.54
145_R	161_D	0.858	0.54
451_G	454_N	0.857	0.54
128_D	203_E	0.856	0.54
145_R	294_R	0.856	0.54
955_E	959_D	0.856	0.54
1043_T	1046_G	0.854	0.54
583_V	1027_R	0.854	0.54
636_K	662_I	0.853	0.54
809_M	832_V	0.853	0.54
454_N	457_N	0.852	0.54
2_P	334_E	0.851	0.53
218_M	254_Q	0.849	0.53
489_L	513_I	0.849	0.53
282_S	300_M	0.848	0.53
373_R	430_D	0.848	0.53
1041_D	1050_T	0.847	0.53
764_V	809_M	0.844	0.53
699_E	703_E	0.843	0.53
348_F	540_T	0.842	0.53
690_P	720_L	0.841	0.53
356_V	387_I	0.840	0.52
768_C	826_M	0.840	0.52
947_L	957_V	0.834	0.52
337_N	530_D	0.834	0.52
525_V	548_E	0.834	0.52
587_L	591_E	0.832	0.52
393_E	496_G	0.831	0.52
489_L	517_R	0.830	0.52
47_V	69_I	0.830	0.52
381_V	601_C	0.829	0.52
149_A	840_I	0.829	0.52
652_R	655_E	0.829	0.52
974_T	1029_I	0.828	0.51
833_K	836_E	0.828	0.51
476_V	480_G	0.828	0.51
321_K	338_D	0.827	0.51
971_L	986_I	0.827	0.51
405_G	408_G	0.827	0.51
265_R	348_F	0.826	0.51
242_I	430_D	0.826	0.51
156_L	164_F	0.826	0.51
424_I	442_A	0.826	0.51
583_V	587_L	0.826	0.51
4_R	10_I	0.825	0.51
74_V	77_I	0.824	0.51
562_I	594_Y	0.824	0.51
1013_I	1029_I	0.822	0.51
385_M	618_F	0.822	0.51
543_M	553_A	0.819	0.51
58_P	858_G	0.819	0.51
489_L	520_Y	0.819	0.51
720_L	852_F	0.819	0.51
396_Q	501_R	0.818	0.51
1025_D	1029_I	0.818	0.51
774_L	859_V	0.818	0.51
654_L	659_V	0.817	0.50
156_L	168_I	0.816	0.50
177_S	899_K	0.815	0.50
570_N	601_C	0.815	0.50
234_I	300_M	0.813	0.50
218_M	272_L	0.809	0.50
532_C	536_F	0.809	0.50
501_R	505_L	0.807	0.50
679_Q	713_V	0.807	0.50
371_N	433_A	0.806	0.50
166_C	206_I	0.806	0.50
689_Q	724_A	0.806	0.50
119_T	224_K	0.805	0.49
810_R	882_E	0.805	0.49
133_D	205_L	0.803	0.49
450_D	454_N	0.802	0.49
565_L	621_V	0.802	0.49
732_A	735_R	0.802	0.49
349_E	530_D	0.802	0.49
141_L	295_L	0.801	0.49
234_I	295_L	0.799	0.49
671_R	681_A	0.798	0.49
348_F	536_F	0.798	0.49
950_R	953_D	0.797	0.49
246_D	374_L	0.794	0.48
724_A	744_V	0.794	0.48
832_V	835_N	0.793	0.48
782_I	795_S	0.793	0.48
815_K	819_E	0.792	0.48
5_T	42_Y	0.792	0.48
511_A	657_A	0.792	0.48
993_K	996_E	0.790	0.48
156_L	159_A	0.789	0.48
168_I	195_G	0.789	0.48
967_Q	1055_N	0.787	0.48
425_R	452_V	0.787	0.48
816_L	826_M	0.786	0.48
262_Q	532_C	0.785	0.48
60_M	64_T	0.785	0.48
337_N	349_E	0.784	0.48
806_Q	813_V	0.784	0.48
234_I	381_V	0.783	0.47
149_A	204_L	0.783	0.47
206_I	264_M	0.783	0.47
763_D	776_G	0.782	0.47
184_N	1006_K	0.781	0.47
741_A	746_N	0.780	0.47
857_T	879_V	0.780	0.47
596_T	866_A	0.779	0.47
213_W	611_D	0.779	0.47
681_A	820_L	0.778	0.47
177_S	377_Q	0.776	0.47
183_Y	211_I	0.776	0.47
85_A	116_I	0.775	0.47
94_T	174_M	0.774	0.47
944_R	1004_R	0.773	0.47
854_S	861_L	0.773	0.47
265_R	530_D	0.772	0.47
410_D	440_A	0.772	0.47
19_V	242_I	0.769	0.46
703_E	706_K	0.769	0.46
337_N	540_T	0.768	0.46
291_K	460_R	0.767	0.46
258_D	265_R	0.767	0.46
623_L	650_L	0.766	0.46
31_A	60_M	0.766	0.46
229_I	601_C	0.766	0.46
348_F	530_D	0.765	0.46
737_Y	742_V	0.764	0.46
676_E	696_T	0.764	0.46
809_M	837_V	0.763	0.46
774_L	880_T	0.763	0.46
1015_N	1029_I	0.762	0.46
343_R	538_T	0.762	0.46
676_E	694_T	0.761	0.46
973_A	977_T	0.761	0.46
124_D	401_G	0.758	0.45
230_I	339_I	0.757	0.45
406_A	413_V	0.757	0.45
1001_I	1029_I	0.757	0.45
1018_S	1026_S	0.755	0.45
359_I	436_I	0.755	0.45
233_S	261_Y	0.755	0.45
393_E	546_T	0.754	0.45
31_A	55_M	0.753	0.45
221_V	324_A	0.752	0.45
102_L	108_L	0.751	0.45
793_A	932_Q	0.751	0.45
166_C	192_C	0.750	0.45
401_G	620_P	0.750	0.45
976_G	993_K	0.749	0.45
723_R	742_V	0.748	0.44
249_T	300_M	0.748	0.44
1002_Q	1032_S	0.748	0.44
762_V	895_L	0.747	0.44
537_A	541_A	0.747	0.44
553_A	556_S	0.746	0.44
989_R	1009_E	0.746	0.44
10_I	862_A	0.745	0.44
388_G	496_G	0.744	0.44
859_V	864_V	0.744	0.44
585_A	866_A	0.744	0.44
780_E	799_Y	0.744	0.44
581_C	862_A	0.743	0.44
347_S	585_A	0.743	0.44
218_M	229_I	0.742	0.44
166_C	182_A	0.742	0.44
665_S	821_Q	0.741	0.44
1031_R	1034_L	0.741	0.44
658_G	770_G	0.740	0.44
774_L	884_I	0.739	0.44
970_E	987_N	0.739	0.44
688_K	837_V	0.738	0.44
588_A	863_K	0.738	0.44
558_D	561_K	0.737	0.44
893_V	931_A	0.736	0.43
162_V	167_I	0.735	0.43
336_M	345_P	0.735	0.43
155_A	205_L	0.734	0.43
134_V	137_K	0.733	0.43
7_I	1049_A	0.733	0.43
47_V	107_V	0.732	0.43
90_M	210_L	0.732	0.43
892_E	932_Q	0.729	0.43
728_V	741_A	0.729	0.43
177_S	921_G	0.729	0.43
249_T	295_L	0.729	0.43
822_V	826_M	0.729	0.43
626_V	650_L	0.728	0.43
501_R	504_K	0.728	0.43
201_T	538_T	0.726	0.43
680_H	686_K	0.726	0.43
233_S	254_Q	0.725	0.42
804_E	808_V	0.725	0.42
424_I	438_Y	0.724	0.42
774_L	864_V	0.723	0.42
698_I	739_Q	0.723	0.42
699_E	735_R	0.721	0.42
130_R	148_I	0.721	0.42
340_T	530_D	0.721	0.42
57_D	580_Y	0.720	0.42
234_I	570_N	0.720	0.42
506_A	513_I	0.720	0.42
363_N	381_V	0.718	0.42
141_L	300_M	0.717	0.42
231_V	253_A	0.717	0.42
974_T	1025_D	0.717	0.42
771_E	818_F	0.716	0.42
428_L	931_A	0.716	0.42
1004_R	1009_E	0.715	0.42
760_V	805_I	0.715	0.42
148_I	171_S	0.714	0.42
170_P	173_T	0.714	0.42
153_E	186_E	0.714	0.42
221_V	231_V	0.712	0.41
762_V	778_I	0.711	0.41
8_K	84_D	0.711	0.41
369_G	912_R	0.711	0.41
406_A	410_D	0.710	0.41
12_I	44_V	0.710	0.41
443_F	447_L	0.710	0.41
271_V	284_V	0.708	0.41
104_R	523_H	0.708	0.41
5_T	10_I	0.708	0.41
701_A	741_A	0.707	0.41
774_L	857_T	0.706	0.41
879_V	883_V	0.706	0.41
79_E	82_R	0.705	0.41
714_V	813_V	0.705	0.41
950_R	1026_S	0.705	0.41
152_M	159_A	0.704	0.41
242_I	373_R	0.704	0.41
258_D	349_E	0.704	0.41
55_M	246_D	0.703	0.41
503_A	508_V	0.703	0.41
730_D	752_L	0.703	0.41
391_Q	465_Q	0.703	0.41
95_A	521_D	0.702	0.41
941_K	969_F	0.702	0.41
362_F	404_V	0.702	0.41
683_E	689_Q	0.702	0.41
493_K	624_E	0.701	0.40
160_A	164_F	0.700	0.40
763_D	896_P	0.700	0.40
760_V	800_T	0.700	0.40
340_T	540_T	0.700	0.40
949_V	953_D	0.698	0.40
816_L	820_L	0.695	0.40
826_M	842_V	0.695	0.40
980_V	983_E	0.695	0.40
172_F	816_L	0.695	0.40
704_K	741_A	0.694	0.40
484_L	513_I	0.694	0.40
180_G	195_G	0.694	0.40
234_I	326_L	0.694	0.40
66_I	576_I	0.694	0.40
73_V	933_L	0.694	0.40
250_V	822_V	0.694	0.40
86_V	986_I	0.693	0.40
526_Y	545_S	0.693	0.40
945_A	964_L	0.693	0.40
729_Y	952_G	0.692	0.40
300_M	381_V	0.691	0.40
893_V	896_P	0.691	0.40
594_Y	636_K	0.691	0.40
323_A	386_A	0.690	0.40
565_L	640_V	0.690	0.40
261_Y	348_F	0.690	0.40
162_V	969_F	0.690	0.40
514_R	628_E	0.690	0.40
782_I	957_V	0.689	0.39
640_V	661_V	0.688	0.39
561_K	636_K	0.688	0.39
981_L	988_P	0.687	0.39
958_V	981_L	0.687	0.39
258_D	337_N	0.686	0.39
551_C	555_P	0.686	0.39
186_E	475_K	0.685	0.39
428_L	455_L	0.684	0.39
756_L	817_A	0.684	0.39
78_I	107_V	0.683	0.39
665_S	668_A	0.683	0.39
806_Q	837_V	0.682	0.39
419_E	424_I	0.682	0.39
785_A	831_A	0.681	0.39
152_M	193_A	0.681	0.39
767_I	879_V	0.681	0.39
992_N	997_G	0.681	0.39
564_V	596_T	0.681	0.39
499_D	514_R	0.681	0.39
289_N	296_I	0.680	0.39
239_A	457_N	0.680	0.39
955_E	980_V	0.680	0.39
78_I	102_L	0.680	0.39
728_V	734_L	0.680	0.39
1032_S	1038_V	0.679	0.39
831_A	896_P	0.679	0.39
960_L	1051_A	0.678	0.39
771_E	875_A	0.678	0.39
131_R	172_F	0.677	0.38
338_D	611_D	0.676	0.38
840_I	1027_R	0.676	0.38
563_M	659_V	0.676	0.38
1048_F	1052_M	0.676	0.38
265_R	535_E	0.674	0.38
279_T	323_A	0.673	0.38
152_M	192_C	0.672	0.38
24_C	381_V	0.672	0.38
409_F	470_V	0.672	0.38
564_V	920_V	0.672	0.38
451_G	455_L	0.671	0.38
249_T	282_S	0.671	0.38
242_I	436_I	0.671	0.38
1000_H	1003_D	0.671	0.38
249_T	381_V	0.670	0.38
570_N	900_F	0.669	0.38
993_K	1000_H	0.669	0.38
42_Y	85_A	0.668	0.38
213_W	294_R	0.668	0.38
249_T	570_N	0.667	0.38
868_V	873_S	0.667	0.38
86_V	107_V	0.666	0.38
177_S	198_L	0.666	0.38
7_I	11_L	0.666	0.38
772_M	814_Q	0.665	0.37
597_I	617_Y	0.664	0.37
993_K	1003_D	0.662	0.37
231_V	593_G	0.662	0.37
324_A	622_T	0.662	0.37
218_M	249_T	0.661	0.37
258_D	340_T	0.661	0.37
419_E	427_E	0.660	0.37
77_I	326_L	0.660	0.37
248_I	466_I	0.660	0.37
135_A	138_K	0.659	0.37
525_V	550_E	0.659	0.37
655_E	666_P	0.658	0.37
173_T	199_S	0.658	0.37
925_A	1056_A	0.658	0.37
599_V	630_V	0.657	0.37
724_A	745_S	0.656	0.37
152_M	168_I	0.656	0.37
143_T	210_L	0.656	0.37
351_S	534_A	0.656	0.37
698_I	738_F	0.656	0.37
825_L	862_A	0.655	0.37
387_I	529_V	0.655	0.37
173_T	179_G	0.655	0.37
535_E	540_T	0.654	0.37
521_D	876_E	0.653	0.36
756_L	832_V	0.653	0.36
714_V	734_L	0.653	0.36
993_K	997_G	0.652	0.36
98_C	107_V	0.651	0.36
810_R	814_Q	0.651	0.36
514_R	631_R	0.650	0.36
6_D	42_Y	0.650	0.36
277_V	565_L	0.650	0.36
344_T	349_E	0.650	0.36
965_L	971_L	0.648	0.36
1036_Y	1039_H	0.648	0.36
339_I	349_E	0.647	0.36
696_T	742_V	0.647	0.36
514_R	518_D	0.647	0.36
771_E	876_E	0.647	0.36
317_F	900_F	0.647	0.36
706_K	710_Y	0.646	0.36
29_S	95_A	0.645	0.36
562_I	637_G	0.645	0.36
493_K	547_Y	0.645	0.36
410_D	413_V	0.645	0.36
265_R	337_N	0.645	0.36
662_I	869_M	0.644	0.36
12_I	34_C	0.644	0.36
119_T	276_G	0.643	0.36
564_V	589_L	0.643	0.36
704_K	752_L	0.643	0.36
268_S	336_M	0.642	0.36
128_D	131_R	0.642	0.36
131_R	264_M	0.642	0.36
456_T	617_Y	0.642	0.36
297_V	953_D	0.642	0.36
975_H	979_I	0.641	0.35
47_V	71_W	0.641	0.35
734_L	741_A	0.640	0.35
943_G	969_F	0.639	0.35
954_K	1015_N	0.638	0.35
917_V	934_G	0.638	0.35
701_A	705_A	0.637	0.35
905_P	1031_R	0.637	0.35
981_L	986_I	0.637	0.35
143_T	146_S	0.636	0.35
452_V	456_T	0.636	0.35
390_T	546_T	0.636	0.35
704_K	707_E	0.636	0.35
100_L	104_R	0.635	0.35
229_I	322_V	0.635	0.35
999_P	1025_D	0.635	0.35
694_T	738_F	0.635	0.35
597_I	615_R	0.635	0.35
929_A	1057_D	0.635	0.35
965_L	986_I	0.634	0.35
812_Q	815_K	0.634	0.35
872_K	875_A	0.633	0.35
207_D	830_F	0.633	0.35
948_S	974_T	0.633	0.35
118_A	279_T	0.633	0.35
451_G	534_A	0.633	0.35
782_I	840_I	0.633	0.35
47_V	78_I	0.632	0.35
813_V	826_M	0.632	0.35
563_M	596_T	0.632	0.35
118_A	249_T	0.632	0.35
34_C	38_R	0.631	0.35
794_C	1043_T	0.631	0.35
249_T	900_F	0.631	0.35
133_D	146_S	0.631	0.35
698_I	702_V	0.630	0.35
8_K	467_E	0.630	0.35
258_D	339_I	0.630	0.35
414_S	438_Y	0.630	0.35
580_Y	584_H	0.630	0.35
469_L	659_V	0.629	0.35
738_F	744_V	0.629	0.35
979_I	982_G	0.628	0.34
339_I	610_Y	0.628	0.34
262_Q	266_N	0.628	0.34
351_S	533_A	0.627	0.34
349_E	535_E	0.627	0.34
973_A	978_A	0.627	0.34
114_T	119_T	0.627	0.34
723_R	741_A	0.624	0.34
707_E	815_K	0.624	0.34
85_A	388_G	0.624	0.34
159_A	168_I	0.624	0.34
7_I	615_R	0.623	0.34
230_I	273_R	0.623	0.34
779_M	796_L	0.623	0.34
15_A	69_I	0.622	0.34
960_L	1044_L	0.621	0.34
363_N	912_R	0.621	0.34
426_R	430_D	0.620	0.34
164_F	168_I	0.620	0.34
543_M	601_C	0.620	0.34
131_R	135_A	0.620	0.34
801_L	806_Q	0.620	0.34
128_D	264_M	0.620	0.34
341_G	469_L	0.619	0.34
963_K	1052_M	0.619	0.34
641_Q	840_I	0.618	0.34
237_F	391_Q	0.618	0.34
956_R	1048_F	0.618	0.34
218_M	234_I	0.618	0.34
171_S	755_F	0.618	0.34
649_K	723_R	0.617	0.34
432_G	438_Y	0.617	0.34
403_E	571_R	0.617	0.34
809_M	870_A	0.616	0.34
993_K	999_P	0.616	0.34
582_C	862_A	0.616	0.34
234_I	275_I	0.616	0.34
265_R	340_T	0.616	0.34
811_Q	814_Q	0.616	0.34
363_N	570_N	0.615	0.33
276_G	279_T	0.615	0.33
862_A	866_A	0.614	0.33
337_N	348_F	0.614	0.33
82_R	107_V	0.614	0.33
24_C	249_T	0.614	0.33
650_L	778_I	0.614	0.33
475_K	923_T	0.613	0.33
49_S	66_I	0.613	0.33
203_E	284_V	0.613	0.33
262_Q	349_E	0.612	0.33
267_A	270_A	0.612	0.33
192_C	196_L	0.612	0.33
796_L	928_F	0.611	0.33
261_Y	534_A	0.611	0.33
450_D	464_V	0.611	0.33
947_L	971_L	0.609	0.33
960_L	1047_G	0.608	0.33
676_E	680_H	0.608	0.33
75_R	116_I	0.608	0.33
443_F	468_E	0.608	0.33
380_S	759_A	0.608	0.33
423_K	427_E	0.607	0.33
265_R	536_F	0.607	0.33
400_R	498_A	0.607	0.33
149_A	192_C	0.607	0.33
586_S	691_A	0.607	0.33
403_E	569_P	0.606	0.33
530_D	534_A	0.606	0.33
724_A	1017_T	0.606	0.33
194_R	714_V	0.605	0.33
300_M	570_N	0.604	0.33
171_S	180_G	0.604	0.33
261_Y	265_R	0.604	0.33
167_I	182_A	0.603	0.33
432_G	662_I	0.603	0.33
142_E	145_R	0.602	0.32
527_K	546_T	0.602	0.32
569_P	601_C	0.602	0.32
156_L	160_A	0.601	0.32
629_I	632_I	0.600	0.32
94_T	388_G	0.600	0.32
421_L	441_D	0.600	0.32
817_A	826_M	0.600	0.32
216_Y	288_V	0.600	0.32
348_F	532_C	0.599	0.32
340_T	349_E	0.599	0.32
561_K	633_E	0.599	0.32
487_D	490_R	0.599	0.32
513_I	521_D	0.599	0.32
503_A	510_E	0.599	0.32
130_R	207_D	0.599	0.32
777_G	853_V	0.597	0.32
727_I	738_F	0.597	0.32
139_I	752_L	0.597	0.32
973_A	981_L	0.597	0.32
425_R	563_M	0.596	0.32
86_V	99_A	0.596	0.32
517_R	522_L	0.596	0.32
256_L	323_A	0.595	0.32
947_L	1014_I	0.595	0.32
492_L	522_L	0.595	0.32
234_I	900_F	0.595	0.32
162_V	166_C	0.595	0.32
530_D	533_A	0.594	0.32
963_K	1048_F	0.592	0.32
355_V	390_T	0.592	0.32
451_G	971_L	0.592	0.32
7_I	945_A	0.592	0.32
428_L	452_V	0.590	0.32
409_F	434_D	0.590	0.32
592_D	866_A	0.590	0.32
227_N	265_R	0.590	0.32
45_I	63_A	0.588	0.31
72_E	101_E	0.587	0.31
193_A	873_S	0.587	0.31
779_M	794_C	0.587	0.31
249_T	279_T	0.587	0.31
488_F	522_L	0.586	0.31
513_I	1001_I	0.586	0.31
1015_N	1025_D	0.586	0.31
703_E	732_A	0.586	0.31
513_I	520_Y	0.586	0.31
291_K	453_F	0.586	0.31
517_R	547_Y	0.586	0.31
201_T	324_A	0.585	0.31
440_A	601_C	0.585	0.31
381_V	647_P	0.585	0.31
423_K	426_R	0.585	0.31
3_K	42_Y	0.585	0.31
153_E	478_E	0.584	0.31
787_V	982_G	0.584	0.31
755_F	925_A	0.584	0.31
262_Q	530_D	0.584	0.31
898_N	1037_K	0.584	0.31
1031_R	1047_G	0.583	0.31
1018_S	1022_A	0.583	0.31
1002_Q	1005_I	0.583	0.31
261_Y	459_D	0.583	0.31
589_L	639_I	0.583	0.31
337_N	535_E	0.583	0.31
262_Q	540_T	0.582	0.31
764_V	837_V	0.582	0.31
896_P	900_F	0.581	0.31
112_G	160_A	0.581	0.31
112_G	521_D	0.581	0.31
381_V	900_F	0.581	0.31
194_R	377_Q	0.581	0.31
652_R	666_P	0.580	0.31
337_N	534_A	0.580	0.31
357_T	391_Q	0.580	0.31
564_V	586_S	0.580	0.31
992_N	996_E	0.580	0.31
89_T	258_D	0.580	0.31
750_V	934_G	0.579	0.31
951_E	1013_I	0.579	0.31
661_V	666_P	0.579	0.31
419_E	423_K	0.579	0.31
167_I	267_A	0.578	0.31
492_L	748_A	0.578	0.31
671_R	684_R	0.578	0.31
456_T	594_Y	0.578	0.31
546_T	778_I	0.578	0.31
976_G	1015_N	0.577	0.31
524_P	625_D	0.577	0.31
856_A	861_L	0.577	0.31
24_C	363_N	0.576	0.30
1002_Q	1006_K	0.576	0.30
230_I	269_M	0.576	0.30
141_L	234_I	0.576	0.30
640_V	658_G	0.576	0.30
640_V	669_I	0.576	0.30
295_L	900_F	0.576	0.30
152_M	189_E	0.575	0.30
206_I	1050_T	0.574	0.30
599_V	1011_T	0.574	0.30
514_R	521_D	0.573	0.30
269_M	1037_K	0.573	0.30
532_C	540_T	0.573	0.30
957_V	980_V	0.572	0.30
429_K	455_L	0.572	0.30
425_R	429_K	0.572	0.30
946_L	974_T	0.572	0.30
295_L	300_M	0.571	0.30
322_V	659_V	0.571	0.30
390_T	707_E	0.570	0.30
945_A	1012_Y	0.570	0.30
763_D	830_F	0.570	0.30
655_E	665_S	0.570	0.30
1008_G	1013_I	0.570	0.30
449_V	453_F	0.569	0.30
234_I	282_S	0.569	0.30
297_V	611_D	0.568	0.30
710_Y	947_L	0.568	0.30
359_I	399_L	0.568	0.30
1_M	330_Y	0.568	0.30
141_L	381_V	0.568	0.30
655_E	677_R	0.567	0.30
144_A	671_R	0.567	0.30
173_T	195_G	0.567	0.30
443_F	469_L	0.567	0.30
363_N	905_P	0.566	0.30
67_E	78_I	0.566	0.30
72_E	735_R	0.566	0.30
530_D	540_T	0.566	0.30
976_G	1026_S	0.566	0.30
561_K	597_I	0.565	0.30
756_L	826_M	0.565	0.30
563_M	636_K	0.565	0.30
100_L	840_I	0.564	0.30
511_A	515_K	0.564	0.30
121_D	124_D	0.564	0.30
186_E	454_N	0.564	0.30
7_I	324_A	0.564	0.30
710_Y	775_I	0.563	0.30
284_V	632_I	0.563	0.30
210_L	297_V	0.563	0.30
708_I	712_L	0.563	0.30
924_F	1049_A	0.563	0.30
552_E	556_S	0.563	0.30
408_G	581_C	0.563	0.30
660_P	869_M	0.562	0.29
959_D	1052_M	0.562	0.29
17_P	22_Q	0.562	0.29
371_N	728_V	0.562	0.29
996_E	999_P	0.561	0.29
779_M	792_S	0.561	0.29
240_M	380_S	0.561	0.29
399_L	403_E	0.561	0.29
3_K	7_I	0.561	0.29
701_A	752_L	0.561	0.29
237_F	254_Q	0.560	0.29
766_A	773_V	0.560	0.29
35_K	612_T	0.560	0.29
216_Y	249_T	0.560	0.29
295_L	570_N	0.560	0.29
499_D	547_Y	0.560	0.29
82_R	667_D	0.560	0.29
439_I	443_F	0.560	0.29
1017_T	1041_D	0.560	0.29
807_D	814_Q	0.559	0.29
2_P	7_I	0.559	0.29
221_V	304_V	0.559	0.29
143_T	272_L	0.559	0.29
960_L	980_V	0.559	0.29
959_D	962_A	0.558	0.29
491_Q	495_K	0.558	0.29
381_V	759_A	0.558	0.29
90_M	795_S	0.558	0.29
999_P	1007_N	0.557	0.29
1017_T	1023_I	0.557	0.29
120_A	124_D	0.556	0.29
967_Q	1010_Y	0.556	0.29
427_E	872_K	0.556	0.29
745_S	749_P	0.555	0.29
639_I	767_I	0.555	0.29
630_V	654_L	0.555	0.29
944_R	947_L	0.555	0.29
649_K	826_M	0.555	0.29
702_V	706_K	0.554	0.29
7_I	42_Y	0.553	0.29
9_S	83_P	0.553	0.29
153_E	189_E	0.553	0.29
1006_K	1036_Y	0.553	0.29
110_E	161_D	0.553	0.29
258_D	535_E	0.553	0.29
8_K	477_A	0.552	0.29
213_W	581_C	0.552	0.29
726_E	1020_R	0.552	0.29
403_E	473_E	0.551	0.29
720_L	897_F	0.551	0.29
700_M	703_E	0.551	0.29
955_E	984_A	0.551	0.29
133_D	210_L	0.551	0.29
226_D	389_R	0.550	0.29
1002_Q	1029_I	0.550	0.29
477_A	703_E	0.550	0.29
449_V	460_R	0.550	0.29
363_N	893_V	0.549	0.28
956_R	1044_L	0.549	0.28
997_G	1000_H	0.549	0.28
237_F	436_I	0.549	0.28
136_M	167_I	0.548	0.28
226_D	272_L	0.548	0.28
667_D	670_D	0.548	0.28
248_I	386_A	0.548	0.28
254_Q	355_V	0.547	0.28
448_S	491_Q	0.547	0.28
521_D	684_R	0.547	0.28
59_E	860_P	0.546	0.28
203_E	264_M	0.546	0.28
413_V	710_Y	0.546	0.28
471_R	474_E	0.546	0.28
167_I	787_V	0.545	0.28
588_A	592_D	0.545	0.28
975_H	992_N	0.545	0.28
157_A	558_D	0.545	0.28
493_K	517_R	0.545	0.28
809_M	905_P	0.544	0.28
272_L	300_M	0.544	0.28
880_T	885_P	0.544	0.28
672_A	766_A	0.544	0.28
1006_K	1032_S	0.544	0.28
803_Q	806_Q	0.544	0.28
261_Y	535_E	0.544	0.28
294_R	399_L	0.543	0.28
90_M	492_L	0.543	0.28
563_M	635_P	0.543	0.28
778_I	798_A	0.543	0.28
317_F	345_P	0.542	0.28
1040_Y	1043_T	0.542	0.28
227_N	349_E	0.541	0.28
85_A	266_N	0.541	0.28
863_K	867_R	0.541	0.28
747_D	750_V	0.541	0.28
778_I	809_M	0.541	0.28
229_I	284_V	0.541	0.28
393_E	862_A	0.541	0.28
263_I	295_L	0.540	0.28
112_G	257_T	0.540	0.28
670_D	1031_R	0.540	0.28
759_A	794_C	0.539	0.28
337_N	538_T	0.539	0.28
233_S	282_S	0.539	0.28
948_S	1029_I	0.539	0.28
115_M	120_A	0.539	0.28
728_V	921_G	0.538	0.28
695_V	745_S	0.538	0.28
595_E	767_I	0.537	0.28
485_N	516_L	0.537	0.28
981_L	984_A	0.537	0.28
78_I	110_E	0.537	0.28
668_A	819_E	0.537	0.28
359_I	384_V	0.537	0.28
974_T	993_K	0.537	0.28
344_T	535_E	0.536	0.28
695_V	762_V	0.535	0.28
133_D	780_E	0.535	0.28
149_A	206_I	0.535	0.28
994_V	1000_H	0.535	0.28
514_R	517_R	0.535	0.28
960_L	967_Q	0.535	0.28
139_I	213_W	0.534	0.27
839_L	939_M	0.534	0.27
204_L	550_E	0.534	0.27
227_N	534_A	0.534	0.27
145_R	296_I	0.533	0.27
281_G	304_V	0.533	0.27
771_E	823_R	0.533	0.27
406_A	411_P	0.533	0.27
582_C	611_D	0.532	0.27
958_V	986_I	0.532	0.27
12_I	991_V	0.532	0.27
773_V	811_Q	0.532	0.27
143_T	221_V	0.532	0.27
553_A	615_R	0.531	0.27
325_K	330_Y	0.531	0.27
724_A	936_N	0.531	0.27
183_Y	998_R	0.531	0.27
45_I	653_A	0.531	0.27
201_T	362_F	0.531	0.27
242_I	998_R	0.530	0.27
73_V	934_G	0.530	0.27
562_I	866_A	0.530	0.27
87_L	99_A	0.530	0.27
120_A	330_Y	0.530	0.27
714_V	724_A	0.530	0.27
110_E	224_K	0.530	0.27
878_G	882_E	0.529	0.27
532_C	541_A	0.529	0.27
213_W	461_W	0.529	0.27
67_E	930_K	0.529	0.27
472_L	476_V	0.528	0.27
599_V	744_V	0.528	0.27
141_L	275_I	0.528	0.27
923_T	1056_A	0.528	0.27
115_M	133_D	0.527	0.27
548_E	552_E	0.527	0.27
410_D	501_R	0.527	0.27
689_Q	692_N	0.527	0.27
272_L	541_A	0.527	0.27
976_G	1025_D	0.527	0.27
650_L	798_A	0.526	0.27
954_K	974_T	0.526	0.27
545_S	612_T	0.526	0.27
450_D	453_F	0.526	0.27
153_E	156_L	0.526	0.27
38_R	730_D	0.525	0.27
90_M	529_V	0.525	0.27
122_A	639_I	0.525	0.27
480_G	516_L	0.525	0.27
728_V	742_V	0.525	0.27
502_L	954_K	0.525	0.27
698_I	747_D	0.525	0.27
448_S	453_F	0.524	0.27
672_A	690_P	0.524	0.27
443_F	453_F	0.523	0.27
143_T	207_D	0.523	0.27
370_A	903_V	0.523	0.27
295_L	381_V	0.523	0.27
57_D	67_E	0.523	0.27
348_F	538_T	0.523	0.27
340_T	348_F	0.523	0.27
759_A	776_G	0.522	0.27
1019_G	1022_A	0.522	0.27
147_G	157_A	0.522	0.27
935_S	939_M	0.522	0.27
80_K	1050_T	0.522	0.27
559_R	614_D	0.522	0.27
323_A	340_T	0.522	0.27
279_T	282_S	0.522	0.27
227_N	530_D	0.521	0.27
36_A	83_P	0.521	0.27
181_I	211_I	0.521	0.27
231_V	412_K	0.521	0.27
422_T	487_D	0.521	0.27
12_I	206_I	0.521	0.27
254_Q	377_Q	0.520	0.26
157_A	202_K	0.520	0.26
214_K	531_T	0.520	0.26
840_I	925_A	0.519	0.26
149_A	429_K	0.519	0.26
213_W	338_D	0.519	0.26
156_L	986_I	0.519	0.26
1_M	334_E	0.519	0.26
263_I	266_N	0.519	0.26
411_P	440_A	0.519	0.26
834_N	985_G	0.518	0.26
502_L	513_I	0.518	0.26
363_N	583_V	0.518	0.26
1012_Y	1048_F	0.518	0.26
584_H	954_K	0.518	0.26
853_V	861_L	0.518	0.26
612_T	840_I	0.518	0.26
682_V	746_N	0.518	0.26
104_R	259_K	0.518	0.26
54_I	682_V	0.518	0.26
261_Y	357_T	0.517	0.26
759_A	928_F	0.517	0.26
958_V	962_A	0.517	0.26
103_E	121_D	0.516	0.26
191_I	949_V	0.516	0.26
768_C	860_P	0.516	0.26
586_S	590_R	0.516	0.26
204_L	211_I	0.516	0.26
491_Q	958_V	0.516	0.26
630_V	867_R	0.516	0.26
152_M	196_L	0.516	0.26
439_I	457_N	0.516	0.26
90_M	543_M	0.516	0.26
211_I	240_M	0.516	0.26
516_L	522_L	0.516	0.26
261_Y	352_I	0.516	0.26
258_D	540_T	0.515	0.26
477_A	597_I	0.515	0.26
815_K	818_F	0.515	0.26
498_A	522_L	0.514	0.26
2_P	330_Y	0.514	0.26
396_Q	567_G	0.514	0.26
551_C	596_T	0.514	0.26
339_I	540_T	0.514	0.26
15_A	1017_T	0.514	0.26
530_D	538_T	0.514	0.26
116_I	622_T	0.514	0.26
19_V	732_A	0.514	0.26
890_V	927_A	0.514	0.26
229_I	272_L	0.514	0.26
931_A	934_G	0.513	0.26
19_V	898_N	0.513	0.26
143_T	681_A	0.513	0.26
319_I	575_G	0.513	0.26
409_F	895_L	0.513	0.26
339_I	541_A	0.512	0.26
948_S	976_G	0.512	0.26
36_A	324_A	0.512	0.26
741_A	917_V	0.512	0.26
227_N	348_F	0.511	0.26
439_I	463_L	0.511	0.26
297_V	729_Y	0.511	0.26
443_F	980_V	0.511	0.26
5_T	967_Q	0.510	0.26
759_A	896_P	0.510	0.26
234_I	363_N	0.509	0.26
1001_I	1028_V	0.509	0.26
258_D	532_C	0.509	0.26
1004_R	1010_Y	0.509	0.26
224_K	687_L	0.509	0.26
152_M	181_I	0.509	0.26
940_K	1012_Y	0.508	0.26
432_G	920_V	0.508	0.26
630_V	635_P	0.508	0.26
575_G	620_P	0.508	0.26
143_T	931_A	0.508	0.26
206_I	452_V	0.507	0.26
67_E	81_E	0.507	0.26
444_R	470_V	0.507	0.26
530_D	536_F	0.507	0.26
166_C	207_D	0.507	0.26
152_M	206_I	0.507	0.26
556_S	559_R	0.506	0.26
227_N	337_N	0.506	0.26
474_E	500_A	0.506	0.26
490_R	707_E	0.506	0.26
1006_K	1010_Y	0.506	0.26
17_P	49_S	0.506	0.26
767_I	777_G	0.506	0.26
538_T	889_S	0.506	0.26
67_E	108_L	0.505	0.25
254_Q	437_W	0.505	0.25
258_D	348_F	0.505	0.25
168_I	971_L	0.505	0.25
82_R	160_A	0.505	0.25
265_R	344_T	0.505	0.25
140_G	143_T	0.505	0.25
166_C	601_C	0.505	0.25
380_S	776_G	0.505	0.25
4_R	328_V	0.505	0.25
840_I	1046_G	0.505	0.25
588_A	591_E	0.504	0.25
31_A	551_C	0.504	0.25
377_Q	931_A	0.504	0.25
171_S	179_G	0.504	0.25
757_D	833_K	0.504	0.25
221_V	230_I	0.504	0.25
411_P	414_S	0.504	0.25
395_L	476_V	0.503	0.25
24_C	601_C	0.503	0.25
684_R	771_E	0.502	0.25
666_P	853_V	0.502	0.25
384_V	402_L	0.502	0.25
672_A	720_L	0.502	0.25
315_T	785_A	0.502	0.25
738_F	980_V	0.501	0.25
588_A	674_D	0.501	0.25
564_V	727_I	0.501	0.25
963_K	1050_T	0.501	0.25
110_E	478_E	0.501	0.25
595_E	614_D	0.501	0.25
1015_N	1019_G	0.501	0.25
840_I	1020_R	0.501	0.25
256_L	459_D	0.501	0.25
19_V	893_V	0.500	0.25
35_K	213_W	0.500	0.25
82_R	807_D	0.500	0.25
570_N	692_N	0.500	0.25

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3jrxA	1	0.3952	100	0.896	Contact Map
3glkA	1	0.3672	100	0.897	Contact Map
3orqA	2	0.3364	100	0.9	Contact Map
2vpqA	2	0.3868	100	0.901	Contact Map
1ulzA	2	0.3914	100	0.902	Contact Map
3q2oA	2	0.3383	100	0.903	Contact Map
1w96A	1	0.3877	100	0.905	Contact Map
2dzdA	2	0.3868	100	0.905	Contact Map
2dwcA	4	0.3476	100	0.909	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0768 seconds.